Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0202
(629 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 128 1e-28
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 123 4e-27
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 122 5e-27
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 122 9e-27
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 116 6e-25
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 111 1e-23
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 111 2e-23
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 106 5e-22
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 99 1e-19
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 97 3e-19
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 97 4e-19
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 97 4e-19
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 93 7e-18
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 92 9e-18
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 92 9e-18
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 91 2e-17
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 87 3e-16
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 84 2e-15
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 78 2e-13
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 73 6e-12
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 73 6e-12
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 70 4e-11
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 70 4e-11
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 70 5e-11
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 69 7e-11
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 68 2e-10
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 68 2e-10
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 68 2e-10
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 67 4e-10
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 66 5e-10
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 66 7e-10
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 66 9e-10
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 65 1e-09
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 64 2e-09
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 64 3e-09
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 61 2e-08
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 61 2e-08
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 61 2e-08
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 60 6e-08
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 59 8e-08
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 59 8e-08
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 58 1e-07
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 58 1e-07
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 58 2e-07
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 58 2e-07
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 57 3e-07
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 57 4e-07
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 57 4e-07
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 57 4e-07
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 56 5e-07
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 56 5e-07
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 56 7e-07
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 56 7e-07
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 56 7e-07
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 56 7e-07
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 56 7e-07
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 56 7e-07
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 56 9e-07
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 56 9e-07
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 56 9e-07
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 55 1e-06
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 55 1e-06
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 54 3e-06
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 54 3e-06
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 54 3e-06
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 54 4e-06
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 54 4e-06
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 54 4e-06
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 53 7e-06
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 53 7e-06
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 52 2e-05
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 52 2e-05
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 51 2e-05
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 51 2e-05
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 51 2e-05
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 51 2e-05
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 51 3e-05
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 50 3e-05
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 50 3e-05
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 50 3e-05
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 50 5e-05
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 50 5e-05
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 50 5e-05
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 49 1e-04
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 48 1e-04
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 48 2e-04
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 48 2e-04
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 47 3e-04
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 47 4e-04
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 47 4e-04
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 47 4e-04
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 47 4e-04
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 46 6e-04
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 46 6e-04
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 46 0.001
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 45 0.001
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 45 0.001
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 45 0.001
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 45 0.002
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 44 0.003
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 43 0.005
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 43 0.005
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 43 0.005
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 43 0.007
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 43 0.007
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 43 0.007
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 43 0.007
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 42 0.012
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 42 0.016
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 42 0.016
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 40 0.037
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 40 0.037
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 40 0.049
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 40 0.065
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 40 0.065
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 39 0.11
UniRef50_A7SAG3 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.15
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 38 0.15
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 38 0.15
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 38 0.20
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 38 0.20
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 38 0.20
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 37 0.35
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 37 0.35
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 37 0.46
UniRef50_UPI00015537B7 Cluster: PREDICTED: hypothetical protein;... 37 0.46
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 37 0.46
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 37 0.46
UniRef50_A7P3R2 Cluster: Chromosome chr1 scaffold_5, whole genom... 36 0.61
UniRef50_A3ZUQ5 Cluster: Two component response regulator; n=1; ... 36 0.80
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.4
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 34 2.4
UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 33 4.3
UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH... 33 4.3
UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein precur... 33 4.3
UniRef50_A5FD47 Cluster: RagB/SusD domain protein precursor; n=1... 33 4.3
UniRef50_Q603D8 Cluster: Putative S-layer protein; n=2; Proteoba... 33 5.7
UniRef50_Q1DER6 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_A4E858 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_Q6ZB96 Cluster: Putative uncharacterized protein OJ1113... 33 5.7
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 33 5.7
UniRef50_A6W5Y8 Cluster: Putative transcriptional regulator, Mer... 33 7.5
UniRef50_A3AIZ4 Cluster: Putative uncharacterized protein; n=3; ... 33 7.5
UniRef50_O26630 Cluster: UDP-N-acetylmuramyl tripeptide syntheta... 33 7.5
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 7.5
UniRef50_A0JM83 Cluster: Uncharacterized protein C1orf174 homolo... 33 7.5
UniRef50_Q0G767 Cluster: Putative uncharacterized protein; n=1; ... 32 9.9
UniRef50_Q01UG3 Cluster: Putative uncharacterized protein precur... 32 9.9
UniRef50_A4X7T9 Cluster: Putative uncharacterized protein; n=1; ... 32 9.9
UniRef50_A3TJH6 Cluster: Putative DNA-binding protein; n=1; Jani... 32 9.9
UniRef50_A2ZQ03 Cluster: Putative uncharacterized protein; n=2; ... 32 9.9
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 128 bits (308), Expect = 1e-28
Identities = 57/86 (66%), Positives = 75/86 (87%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
AADLSH++T AKV+ H+GP++L AA++ VV IPAGVPRKPGMTRDDLFNTNASIV+++
Sbjct: 9 AADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVKNL 68
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPL 512
+ + A++ PKAI+ II+NPVNSTVP+
Sbjct: 69 SEACAKHCPKAIICIISNPVNSTVPI 94
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/26 (84%), Positives = 24/26 (92%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVV 586
IASEV KKAGVYDP R+LGVTTLD+V
Sbjct: 94 IASEVYKKAGVYDPARILGVTTLDIV 119
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 123 bits (296), Expect = 4e-27
Identities = 55/94 (58%), Positives = 73/94 (77%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
AADLSH NTP++V GP EL+ +KD +VVVIPAGVPRKPGMTRDDLFN NA+IV+ +
Sbjct: 123 AADLSHCNTPSQVRDFTGPSELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTL 182
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRRR 536
++A+N P A + II+NPVNSTVP+ + +++
Sbjct: 183 VEAVAENCPNAFIHIISNPVNSTVPIAAEVLKKK 216
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/26 (76%), Positives = 23/26 (88%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVV 586
IA+EVLKK GVYDP ++ GVTTLDVV
Sbjct: 208 IAAEVLKKKGVYDPKKLFGVTTLDVV 233
Score = 38.3 bits (85), Expect = 0.15
Identities = 17/24 (70%), Positives = 21/24 (87%)
Frame = +1
Query: 166 IGQPLALLLKQNPLVTRLALYDIA 237
IGQPL+LL+K +PLV+ L LYDIA
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIA 117
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 122 bits (295), Expect = 5e-27
Identities = 57/89 (64%), Positives = 69/89 (77%)
Frame = +3
Query: 246 PRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 425
P AADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 426 RDIALSIAQNAPKAIVAIITNPVNSTVPL 512
+ + AQ+ P+A+V II NPVNST+P+
Sbjct: 122 ATLTAACAQHCPEAMVCIIANPVNSTIPI 150
Score = 56.0 bits (129), Expect = 7e-07
Identities = 30/62 (48%), Positives = 40/62 (64%)
Frame = +1
Query: 52 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 231
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 232 IA 237
IA
Sbjct: 58 IA 59
Score = 49.2 bits (112), Expect = 8e-05
Identities = 21/40 (52%), Positives = 28/40 (70%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
I +EV KK GVY+PN++ GVTTLD+V A + G+DP
Sbjct: 150 ITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDP 189
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 122 bits (293), Expect = 9e-27
Identities = 55/89 (61%), Positives = 69/89 (77%)
Frame = +3
Query: 246 PRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 425
P AADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 426 RDIALSIAQNAPKAIVAIITNPVNSTVPL 512
+ + AQ+ P+A++ +I NPVNST+P+
Sbjct: 122 ATLTAACAQHCPEAMICVIANPVNSTIPI 150
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/62 (46%), Positives = 40/62 (64%)
Frame = +1
Query: 52 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 231
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 232 IA 237
IA
Sbjct: 58 IA 59
Score = 49.2 bits (112), Expect = 8e-05
Identities = 21/40 (52%), Positives = 28/40 (70%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
I +EV KK GVY+PN++ GVTTLD+V A + G+DP
Sbjct: 150 ITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDP 189
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 116 bits (278), Expect = 6e-25
Identities = 54/90 (60%), Positives = 73/90 (81%), Gaps = 1/90 (1%)
Frame = +3
Query: 246 PRRAADLSHMNTPAKVSGHKG-PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 422
P AAD+SH+NT + V G++ P L A+K +++++IPAGVPRKPGMTRDDLFNTNASI
Sbjct: 61 PGVAADISHINTNSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASI 120
Query: 423 VRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
VRD+A + A+ AP+A + +I+NPVNSTVP+
Sbjct: 121 VRDLAKAAAEAAPEANILVISNPVNSTVPI 150
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/44 (52%), Positives = 30/44 (68%)
Frame = +1
Query: 103 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI 234
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDI 57
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/40 (50%), Positives = 26/40 (65%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
I SEV K GVY+P R+ GVTTLDVV +++ G +P
Sbjct: 150 IVSEVYKSKGVYNPKRLFGVTTLDVVRASRFISQVKGTNP 189
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 111 bits (267), Expect = 1e-23
Identities = 54/89 (60%), Positives = 64/89 (71%)
Frame = +3
Query: 246 PRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 425
P AD+SHMNT A V G G +L A+ D+V+IPAGVPRKPGMTRDDLFN NA IV
Sbjct: 82 PGVTADISHMNTGAVVRGFLGQPQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIV 141
Query: 426 RDIALSIAQNAPKAIVAIITNPVNSTVPL 512
R + IA+ P AIV +I+NPVNSTVP+
Sbjct: 142 RTLCEGIAKCCPNAIVNVISNPVNSTVPI 170
Score = 52.8 bits (121), Expect = 7e-06
Identities = 25/40 (62%), Positives = 29/40 (72%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
IA+EV KKAG YDP R+LGVTTLDVV A + G+DP
Sbjct: 170 IAAEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLDP 209
Score = 39.5 bits (88), Expect = 0.065
Identities = 19/34 (55%), Positives = 22/34 (64%)
Frame = +1
Query: 133 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI 234
FK IGQPLALL+K NPLV+ L LYD+
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDV 78
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 111 bits (266), Expect = 2e-23
Identities = 54/97 (55%), Positives = 69/97 (71%), Gaps = 1/97 (1%)
Frame = +3
Query: 246 PRRAADLSHMNTPAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 422
P AAD+ H+NT + V G+ ++ L A+ ADVV+IPAGVPRKPGMTRDDLF TNASI
Sbjct: 66 PGVAADIGHINTTSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASI 125
Query: 423 VRDIALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRR 533
VRD+A + + P+A ++TNPVNSTVP+ K R
Sbjct: 126 VRDLAFAAGETCPEAKYLVVTNPVNSTVPIFKKALER 162
Score = 46.4 bits (105), Expect = 6e-04
Identities = 23/44 (52%), Positives = 29/44 (65%)
Frame = +1
Query: 103 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI 234
++FSTTS R FK IGQPL++LLK N V+ LAL+DI
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDI 62
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 106 bits (254), Expect = 5e-22
Identities = 53/91 (58%), Positives = 69/91 (75%), Gaps = 5/91 (5%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEE-----LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 419
AADLSH+ +PAKV+G++ + + A+ ++D+VVIPAGVPRKPGMTR DLFN NAS
Sbjct: 42 AADLSHICSPAKVTGYQPSSKEDRDTIQKALVNSDLVVIPAGVPRKPGMTRADLFNINAS 101
Query: 420 IVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
I+RDI SI + P A + II+NPVNSTVP+
Sbjct: 102 IIRDIVGSIGKACPNAAILIISNPVNSTVPI 132
Score = 39.1 bits (87), Expect = 0.086
Identities = 17/26 (65%), Positives = 22/26 (84%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVV 586
IA+EVLKK GV++P ++ GVTTLD V
Sbjct: 132 IAAEVLKKLGVFNPKKLFGVTTLDSV 157
Score = 35.9 bits (79), Expect = 0.80
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +1
Query: 166 IGQPLALLLKQNPLVTRLALYDI 234
IGQPL+LLLK NP V+ L+L+D+
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDV 35
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 98.7 bits (235), Expect = 1e-19
Identities = 46/93 (49%), Positives = 68/93 (73%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DLSH+NT A G+ +++ A+K A VVVIPAGVPR+PG+TRDDLF NA IV+++
Sbjct: 42 ATDLSHINTNADCVGYS-TDDIGQALKGAAVVVIPAGVPRRPGITRDDLFKLNAGIVKNL 100
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRR 533
++A++ P A + II+NPVNS +P+ ++ +R
Sbjct: 101 VSNVAKHCPNARLLIISNPVNSLIPVAVETLKR 133
Score = 36.7 bits (81), Expect = 0.46
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +1
Query: 166 IGQPLALLLKQNPLVTRLALYDI 234
+GQPL+LLLK N +++ LALYDI
Sbjct: 13 VGQPLSLLLKLNTMISELALYDI 35
Score = 33.9 bits (74), Expect = 3.2
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVV 586
+A E LK+ GV+ V+GVTTLD+V
Sbjct: 126 VAVETLKRCGVFQAGNVMGVTTLDLV 151
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 97.1 bits (231), Expect = 3e-19
Identities = 47/87 (54%), Positives = 60/87 (68%), Gaps = 2/87 (2%)
Frame = +3
Query: 258 ADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 437
ADLSH++TP VS H + + +A +VVIPAGVPRKPGMTRDDLFN NA I+ +
Sbjct: 68 ADLSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLG 127
Query: 438 LSIAQ--NAPKAIVAIITNPVNSTVPL 512
SIA+ + K V +I+NPVNS VP+
Sbjct: 128 DSIAECCDLSKVFVLVISNPVNSLVPV 154
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 96.7 bits (230), Expect = 4e-19
Identities = 44/68 (64%), Positives = 52/68 (76%)
Frame = +3
Query: 258 ADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 437
ADL H NTPAKV+G G EEL+ + DVVVIPAGVPRKPGMTRDDLF NA IVR++
Sbjct: 119 ADLGHCNTPAKVAGFTGKEELAGCLAGVDVVVIPAGVPRKPGMTRDDLFGINAGIVRELV 178
Query: 438 LSIAQNAP 461
++A +AP
Sbjct: 179 EAVADHAP 186
Score = 37.9 bits (84), Expect = 0.20
Identities = 17/24 (70%), Positives = 21/24 (87%)
Frame = +1
Query: 166 IGQPLALLLKQNPLVTRLALYDIA 237
IGQPL+LL+K +PLV+ L LYDIA
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIA 112
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 96.7 bits (230), Expect = 4e-19
Identities = 52/96 (54%), Positives = 65/96 (67%), Gaps = 7/96 (7%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGH-----KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 419
AADLSH+NTP +VS H + E L A+ A VVVIPAGVPRKPGMTRDDL N NA
Sbjct: 74 AADLSHVNTPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAG 133
Query: 420 IVRDIALSIAQ--NAPKAIVAIITNPVNSTVPLPLK 521
I++ +A IA + K V +I+NPVNS VP+ ++
Sbjct: 134 IIKTLAKGIAGACDLEKVFVLVISNPVNSLVPVMVR 169
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 92.7 bits (220), Expect = 7e-18
Identities = 49/93 (52%), Positives = 61/93 (65%), Gaps = 7/93 (7%)
Frame = +3
Query: 255 AADLSHM-NTPAKVS------GHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTN 413
AADLSH+ N +V GHK L+ K DV V+ AGVPRKPGMTRDDLF N
Sbjct: 43 AADLSHVDNAGVQVKFAEGKIGHKRDPALAELAKGVDVFVMVAGVPRKPGMTRDDLFKIN 102
Query: 414 ASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
A I+ D+ L+ A ++PKA+ I+TNPVNSTV +
Sbjct: 103 AGIILDLVLTCASSSPKAVFCIVTNPVNSTVAI 135
Score = 37.5 bits (83), Expect = 0.26
Identities = 17/25 (68%), Positives = 20/25 (80%)
Frame = +2
Query: 506 AIASEVLKKAGVYDPNRVLGVTTLD 580
AIA+E LK GVYD NR+LGV+ LD
Sbjct: 134 AIAAEALKSLGVYDRNRLLGVSLLD 158
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 92.3 bits (219), Expect = 9e-18
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = +3
Query: 261 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 440
DLSH+NT A V +G L A+ AD+VVIPAG+PRKPGM R+DL + NAS+ ++A
Sbjct: 70 DLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAF 129
Query: 441 SIAQNAPKAIVAIITNPVNSTVPL 512
+ ++ P A++A ITNP+N VP+
Sbjct: 130 AASEVCPGAMLAFITNPINVIVPI 153
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/40 (55%), Positives = 25/40 (62%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
I + +LK G YDPNR+ GVTTLDVV A I VDP
Sbjct: 153 IVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDP 192
Score = 38.3 bits (85), Expect = 0.15
Identities = 18/36 (50%), Positives = 22/36 (61%)
Frame = +1
Query: 127 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI 234
R K IGQPL+LLLK NP ++ L+LYDI
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDI 61
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 92.3 bits (219), Expect = 9e-18
Identities = 43/93 (46%), Positives = 67/93 (72%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DLSH KV+G+ + + A+ AD+V++ AG+PR+PGMT DDLFNTNA V ++
Sbjct: 49 AVDLSHFPRKVKVTGYP-TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNEL 107
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRR 533
+ ++A+ APK+++AII+NP+NS VP+ + +R
Sbjct: 108 SAAVARYAPKSVLAIISNPLNSMVPVAAETLQR 140
Score = 36.3 bits (80), Expect = 0.61
Identities = 14/40 (35%), Positives = 25/40 (62%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
+A+E L++AGVYDP ++ G+ +L+++ G DP
Sbjct: 133 VAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTGQDP 172
Score = 35.9 bits (79), Expect = 0.80
Identities = 19/34 (55%), Positives = 20/34 (58%)
Frame = +1
Query: 133 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI 234
FK IGQPLAL L QN V+ LALYDI
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI 42
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 91.5 bits (217), Expect = 2e-17
Identities = 41/91 (45%), Positives = 63/91 (69%)
Frame = +3
Query: 261 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 440
DLSH+NT + G+ + + + +A VV+IPAGVPRKPG+TRDDLF NA IV+ +
Sbjct: 44 DLSHINTNSSCVGYD-KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT 102
Query: 441 SIAQNAPKAIVAIITNPVNSTVPLPLKCSRR 533
++ + AP A + +I+NPVNS VP+ ++ ++
Sbjct: 103 AVGKFAPNARILVISNPVNSLVPIAVETLKK 133
Score = 37.1 bits (82), Expect = 0.35
Identities = 16/23 (69%), Positives = 20/23 (86%)
Frame = +1
Query: 166 IGQPLALLLKQNPLVTRLALYDI 234
+GQPL+LLLK +P V+ LALYDI
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDI 35
Score = 33.5 bits (73), Expect = 4.3
Identities = 15/26 (57%), Positives = 18/26 (69%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVV 586
IA E LKK G + P V+GVT LD+V
Sbjct: 126 IAVETLKKMGKFKPGNVMGVTNLDLV 151
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 89.0 bits (211), Expect = 8e-17
Identities = 44/85 (51%), Positives = 60/85 (70%)
Frame = +3
Query: 258 ADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 437
ADLSH+NT K+S H + L ++ D+++V+IPAGVPRKPGMTRDDLFN NA I++ IA
Sbjct: 89 ADLSHVNTNMKLSLH---DNLRDSLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIA 145
Query: 438 LSIAQNAPKAIVAIITNPVNSTVPL 512
+ V +I+NPVNS +P+
Sbjct: 146 QELNTIDSTPFVLLISNPVNSLLPV 170
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 87.0 bits (206), Expect = 3e-16
Identities = 41/85 (48%), Positives = 56/85 (65%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DLSH++ KV G G +EL +A+ ADVVV+ AG+PR PGM RD L N ++ +
Sbjct: 63 ATDLSHISQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKV 122
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVP 509
A +I+ +P+A +A ITNPVN VP
Sbjct: 123 ATAISNASPRAHLAFITNPVNMIVP 147
Score = 32.7 bits (71), Expect = 7.5
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +2
Query: 512 ASEVLKKAGVYDPNRVLGVTTLDVV 586
A+EVL G +D R+ G+TTLDVV
Sbjct: 149 AAEVLMAHGTFDSRRLFGITTLDVV 173
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 85.4 bits (202), Expect = 1e-15
Identities = 38/90 (42%), Positives = 62/90 (68%), Gaps = 1/90 (1%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DLSH+NT + G+ E+ ++ +++V++ AG+PRKPGMTRDDLF NA I++++
Sbjct: 43 AKDLSHINTNSDSEGYNKDEDFKNLLEGSELVIVTAGIPRKPGMTRDDLFKINAKIIQNL 102
Query: 435 ALSIAQNAP-KAIVAIITNPVNSTVPLPLK 521
+ A+ AP + II+NPVNS +P+ ++
Sbjct: 103 TVKYAKFAPVHCKLLIISNPVNSLIPVVIE 132
Score = 39.1 bits (87), Expect = 0.086
Identities = 18/24 (75%), Positives = 21/24 (87%)
Frame = +1
Query: 166 IGQPLALLLKQNPLVTRLALYDIA 237
IGQPL+LLLK NP V+ LALYDI+
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDIS 36
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/91 (46%), Positives = 59/91 (64%), Gaps = 5/91 (5%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEE---LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 425
AADLSH++TP + H + + + +A VV+IPAGVPRKPGM+RDDL NA I+
Sbjct: 98 AADLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKII 157
Query: 426 RDIALSIAQ--NAPKAIVAIITNPVNSTVPL 512
+ + IA+ + K V +I+NP+NS VPL
Sbjct: 158 KSLGEDIAKYCDLNKVHVLVISNPINSLVPL 188
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 78.2 bits (184), Expect = 2e-13
Identities = 40/91 (43%), Positives = 53/91 (58%), Gaps = 6/91 (6%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGH------KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNA 416
A DL H+ A V G+ K + L + +V+IPAG+PRKPG TRDDLF NA
Sbjct: 125 ATDLGHLEKKAAVKGYVMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINA 184
Query: 417 SIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
I + I + A+ P A++ +I NPVNS VP
Sbjct: 185 DIAKGIVEACAKYCPDAMLGMIVNPVNSVVP 215
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 72.9 bits (171), Expect = 6e-12
Identities = 30/48 (62%), Positives = 40/48 (83%)
Frame = +3
Query: 369 PRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
PRKPGMTRDDLFNTNAS+V + AQ+ P+A++ +I+NPVNST+P+
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPI 108
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/37 (54%), Positives = 25/37 (67%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARING 619
IA+EV KK G YDPN++ VTTLD+V A +NG
Sbjct: 108 IATEVFKKHGAYDPNKIFRVTTLDIVRANTFIAELNG 144
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 72.9 bits (171), Expect = 6e-12
Identities = 33/61 (54%), Positives = 45/61 (73%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
I DA +V+I AGVPRKPGM+R DL TNA IVR +A +IA+ AP A+V +++NP++
Sbjct: 85 IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMTA 144
Query: 510 L 512
L
Sbjct: 145 L 145
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 70.1 bits (164), Expect = 4e-11
Identities = 39/95 (41%), Positives = 58/95 (61%)
Frame = +3
Query: 237 ACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNA 416
A D +AA+ + +T K + KGPE++ + DVV+I AG PR PGM+RDDL NA
Sbjct: 46 ALDMSQAANAARQHTIVKAA--KGPEDMEGS----DVVIITAGAPRTPGMSRDDLLFKNA 99
Query: 417 SIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLK 521
IV+ + I + AP AIV +++NP++ + LK
Sbjct: 100 DIVKCYSREIKEYAPDAIVIVVSNPLDVMTYVALK 134
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 70.1 bits (164), Expect = 4e-11
Identities = 31/61 (50%), Positives = 43/61 (70%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
AAI+ ADVV++ AGVPRKPGM+RDDL N ++ + I + AP+A V ITNP+++
Sbjct: 67 AAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAM 126
Query: 504 V 506
V
Sbjct: 127 V 127
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 69.7 bits (163), Expect = 5e-11
Identities = 30/66 (45%), Positives = 48/66 (72%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
A ++DVVVI +G+PRKPGMTR++L NA IV+ +A ++ + +P AI+ +I+NP+++
Sbjct: 67 AQTANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTM 126
Query: 504 VPLPLK 521
L LK
Sbjct: 127 TYLALK 132
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 69.3 bits (162), Expect = 7e-11
Identities = 31/61 (50%), Positives = 42/61 (68%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
+ +KDADV+++ AGVPRKPGM+RDDL NA I+ + +I Q P A V ITNP++
Sbjct: 221 SVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVM 280
Query: 504 V 506
V
Sbjct: 281 V 281
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 68.1 bits (159), Expect = 2e-10
Identities = 40/96 (41%), Positives = 59/96 (61%), Gaps = 4/96 (4%)
Frame = +3
Query: 252 RAADLSHM----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 419
RA DLSH+ N ++SG E L +K++D+VVI AG R+ G +R DL N NA
Sbjct: 42 RALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKTRQAGQSRADLLNDNAK 97
Query: 420 IVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLKCS 527
I+ A ++A+ AP+AI+ +ITNPV++ + K S
Sbjct: 98 IISSCAKNVAKYAPEAIIILITNPVDTLAFVAYKAS 133
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/95 (40%), Positives = 61/95 (64%)
Frame = +3
Query: 213 QAGFIRHSACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 392
Q G + +A D +++A L + A+V+G E I D+D+VVI AG PRKPGM+R
Sbjct: 37 QEGVAQGAALDIQQSAPLFDFD--ARVTGSTNYE----LIADSDLVVITAGKPRKPGMSR 90
Query: 393 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
D+ ++N I+ DI ++ + AP+++V I+TNPV+
Sbjct: 91 SDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD 125
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 67.7 bits (158), Expect = 2e-10
Identities = 31/64 (48%), Positives = 44/64 (68%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLP 515
DADV+V+ AG+PRKPG TR DL NA+I++ +A+ P+AIV ++TNPV+ +
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVA 132
Query: 516 LKCS 527
LK S
Sbjct: 133 LKVS 136
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 66.9 bits (156), Expect = 4e-10
Identities = 30/61 (49%), Positives = 40/61 (65%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
A I ADV ++ AGVPRKPGM+RDDL N +++ + I NAP A V ITNP+++
Sbjct: 67 ADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAM 126
Query: 504 V 506
V
Sbjct: 127 V 127
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 66.5 bits (155), Expect = 5e-10
Identities = 34/85 (40%), Positives = 50/85 (58%)
Frame = +3
Query: 252 RAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 431
+A DL H +T V+ + IKDAD++VI AGV RK GMTR+DL N I++
Sbjct: 41 KALDLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTREDLIGVNGKIMKS 100
Query: 432 IALSIAQNAPKAIVAIITNPVNSTV 506
+A S+ + KA V ++NP++ V
Sbjct: 101 VAESVKLHCSKAFVICVSNPLDIMV 125
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 66.1 bits (154), Expect = 7e-10
Identities = 26/56 (46%), Positives = 44/56 (78%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+K ++++V+ AG+ RKPGMTR DL + NA I++DIA I +NAP++ + ++TNP++
Sbjct: 67 LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMD 122
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 65.7 bits (153), Expect = 9e-10
Identities = 36/80 (45%), Positives = 52/80 (65%), Gaps = 2/80 (2%)
Frame = +3
Query: 264 LSHMNTPAKVSGHK-GPE-ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 437
L+ M+ A+V G+ PE E ++ +D+VVI AG PR+PGM+R+DL N I+ IA
Sbjct: 59 LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118
Query: 438 LSIAQNAPKAIVAIITNPVN 497
I + AP AIV ++TNPV+
Sbjct: 119 DRIKRYAPDAIVIVVTNPVD 138
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 65.3 bits (152), Expect = 1e-09
Identities = 33/68 (48%), Positives = 46/68 (67%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
A I+ +D+VV+ AG PRK G TR+DL NA +V+ A +IA+ AP AIV I+TNP++
Sbjct: 65 ALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVM 124
Query: 504 VPLPLKCS 527
V L+ S
Sbjct: 125 VWTVLRYS 132
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/83 (38%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +3
Query: 255 AADLSHMNTPAKVS-GHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 431
A D++HM++ + + G E I+ +D++++ AG+PRKPGMTR+ L NA IV +
Sbjct: 41 ALDMNHMSSILGLDVEYVGSNEYKD-IEGSDLIIVTAGLPRKPGMTREQLLEANAKIVAE 99
Query: 432 IALSIAQNAPKAIVAIITNPVNS 500
I I + AP +IV + TNP+++
Sbjct: 100 IGREIKKYAPDSIVILTTNPLDA 122
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 64.1 bits (149), Expect = 3e-09
Identities = 27/58 (46%), Positives = 44/58 (75%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
A +K +DVV++ AGVP+KPG TR L NA ++++IA ++++ AP +IV ++TNPV+
Sbjct: 63 ADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD 120
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 61.3 bits (142), Expect = 2e-08
Identities = 22/56 (39%), Positives = 43/56 (76%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
++ +DV+V+ AG+ RKPGM+R+DLF+ N I+ D++ +I + +P +I+ +++NP +
Sbjct: 74 MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPAD 129
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 61.3 bits (142), Expect = 2e-08
Identities = 24/57 (42%), Positives = 46/57 (80%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 500
I +++VV+I AG PR P MTR+DL NASI+++I+ ++A+ AP++++ +++NP+++
Sbjct: 70 IAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDA 126
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +3
Query: 243 DPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 422
D AD++ + P K+ + G E +A DADVVVI AG+PRKPG TR DL N N +I
Sbjct: 48 DAADLADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTI 102
Query: 423 VRDIALSIAQNAPKAIVAIITNPVN 497
++ I I ++ + I +NPV+
Sbjct: 103 LKSIIKPIVKSGFTGVFVISSNPVD 127
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 59.7 bits (138), Expect = 6e-08
Identities = 25/54 (46%), Positives = 40/54 (74%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
D+DVVVI AG+ RKPGM+R++L + NA IV + + Q++P + + I++NPV+
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVD 124
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 59.3 bits (137), Expect = 8e-08
Identities = 29/86 (33%), Positives = 53/86 (61%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DL++++T +V+ G +++ A+ ++++V+ + LF+ NA IV+D+
Sbjct: 69 ANDLNYVDTKCRVTSFFGNKDIQKALTKSNIIVVLSCCHAAEPTNYASLFDRNAPIVKDL 128
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPL 512
A SIA+ +PK+ VAI P+NS VP+
Sbjct: 129 ATSIAKFSPKSTVAIGVEPINSVVPM 154
Score = 38.7 bits (86), Expect = 0.11
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +2
Query: 515 SEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
SE++KK G Y+P + G+TT+DVV A I G++P
Sbjct: 156 SEIMKKYGHYNPYSIFGITTVDVVRTNKFVAEILGLEP 193
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 59.3 bits (137), Expect = 8e-08
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
+KD D+VVI AG RK G +RDDL NA IV + +++ APK+I+ ++TNP++ V
Sbjct: 67 LKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVY 126
Query: 510 LPLK 521
+ K
Sbjct: 127 VAFK 130
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/73 (41%), Positives = 43/73 (58%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
I AD+VVI AG PRKPGM+R DLF NA I+ D+A + + A+ ++ NPV+
Sbjct: 68 ISGADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDMMAS 127
Query: 510 LPLKCSRRRECTT 548
+ +K S +T
Sbjct: 128 VFMKYSGENTIST 140
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 258 ADLSHMN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 431
ADL+H TPA V G G + A D+DVV I AG +KPG TR DL NA+I+R
Sbjct: 53 ADLAHGTQFTPASVMG--GADVHDTA--DSDVVFITAGARQKPGQTRLDLAGVNANILRS 108
Query: 432 IALSIAQNAPKAIVAIITNP 491
+ + + +P A+ ++TNP
Sbjct: 109 LMPQLVEQSPNALFVLVTNP 128
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 57.6 bits (133), Expect = 2e-07
Identities = 24/56 (42%), Positives = 41/56 (73%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
I+ + VVV+ AG RKPGM+R+DL + N I+ ++A I ++AP ++V ++TNP++
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMD 127
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 57.6 bits (133), Expect = 2e-07
Identities = 27/47 (57%), Positives = 35/47 (74%)
Frame = +3
Query: 396 DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRRR 536
DLFNTNA IVRD+ IA+ P A++ IITNPVNSTVP+ + ++R
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEVLKKR 47
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/39 (66%), Positives = 27/39 (69%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVD 625
IASEVLKK GVYDP RV GVTTLDVV A G+D
Sbjct: 39 IASEVLKKRGVYDPKRVFGVTTLDVVRSNTFIAEAKGLD 77
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/92 (32%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGH-KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 431
A D++HM + +G + S ++ +D+VV+ AG RKPGMTR DL NA IV+
Sbjct: 41 AMDINHMLAEQGIDTEVRGSNDYSD-MEGSDIVVVVAGAGRKPGMTRMDLLKINAGIVKG 99
Query: 432 IALSIAQNAPKAIVAIITNPVNSTVPLPLKCS 527
+ + ++A +++ +TNP++ + K S
Sbjct: 100 VVEKVKEHAKDSMIIPVTNPLDPITYIAYKTS 131
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 56.8 bits (131), Expect = 4e-07
Identities = 28/54 (51%), Positives = 34/54 (62%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 491
+ DAD+VVI AG K G TRDDL N+ I DIA I AP AI+ ++TNP
Sbjct: 68 LTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNP 121
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 56.8 bits (131), Expect = 4e-07
Identities = 27/66 (40%), Positives = 43/66 (65%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
++ +D++V+ +GVPRK TR DL NA IV+ A + + AP+AI+ ++TNPV+
Sbjct: 71 LRGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIMTT 130
Query: 510 LPLKCS 527
+ LK S
Sbjct: 131 VALKYS 136
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/81 (44%), Positives = 42/81 (51%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DLSH P S K A KDAD+VVI AG+P+KPG TR DL N I + I
Sbjct: 47 AMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQI 105
Query: 435 ALSIAQNAPKAIVAIITNPVN 497
I + I I TNPV+
Sbjct: 106 VRGIMDSGFDGIFLIATNPVD 126
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 56.4 bits (130), Expect = 5e-07
Identities = 24/63 (38%), Positives = 42/63 (66%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPL 518
+++VVI AG+ RKPGMTR++L N I+ D+ + + +P+A + +++NPV++ L
Sbjct: 70 SEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLAW 129
Query: 519 KCS 527
K S
Sbjct: 130 KLS 132
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 56.4 bits (130), Expect = 5e-07
Identities = 27/83 (32%), Positives = 48/83 (57%)
Frame = +3
Query: 273 MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 452
M+ V G +E +K +D+VVI AG+PR+ GM+R+DL N I++ +I +
Sbjct: 67 MDIDINVKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKE 126
Query: 453 NAPKAIVAIITNPVNSTVPLPLK 521
A +I+ +++NPV++ +K
Sbjct: 127 YAKDSIIIVVSNPVDTLTYATIK 149
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 56.0 bits (129), Expect = 7e-07
Identities = 26/56 (46%), Positives = 35/56 (62%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+++AD +VI AG PRK M+R DL NA I+RDI + P A +ITNPV+
Sbjct: 72 VENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVD 127
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 56.0 bits (129), Expect = 7e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A D++HM + + +K +++VV+ AG RKPGMTR DL NASIV+ +
Sbjct: 41 AMDINHMLSEQGIDVEVKGSNNFEDMKGSNIVVVVAGSGRKPGMTRMDLLKINASIVKSV 100
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPLPLKCS 527
++ + A +++ +TNP++ + K S
Sbjct: 101 VENVKKYADDSMIIPVTNPLDPMAYITYKVS 131
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 56.0 bits (129), Expect = 7e-07
Identities = 29/61 (47%), Positives = 38/61 (62%)
Frame = +3
Query: 345 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLKC 524
+VVI AGVPR M RDDL N IV D A IA+ AP +I+ ++TNPV+ + L+
Sbjct: 75 IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVALRY 134
Query: 525 S 527
S
Sbjct: 135 S 135
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 56.0 bits (129), Expect = 7e-07
Identities = 23/54 (42%), Positives = 38/54 (70%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 500
+DV+V+ AG R+PGM+RDDL TN IV ++ ++P+A V ++TNP+++
Sbjct: 77 SDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDA 130
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 56.0 bits (129), Expect = 7e-07
Identities = 26/65 (40%), Positives = 40/65 (61%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
KD+D+V+I AG KPG TR DL N N I + I + + +PK+I+ +++NPV+ +
Sbjct: 71 KDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVDILTYV 130
Query: 513 PLKCS 527
K S
Sbjct: 131 TYKLS 135
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 56.0 bits (129), Expect = 7e-07
Identities = 26/68 (38%), Positives = 41/68 (60%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
A KD+D+V+I AGV KPG TR D+ N N I + I + + +P +I+ +++NPV+
Sbjct: 69 ADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVDIL 128
Query: 504 VPLPLKCS 527
+ K S
Sbjct: 129 TYITYKLS 136
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 55.6 bits (128), Expect = 9e-07
Identities = 26/55 (47%), Positives = 36/55 (65%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
KDAD++VI AGVPR PG TR D+ + + VRDI ++ + K I+ ITNP +
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD 125
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 55.6 bits (128), Expect = 9e-07
Identities = 26/89 (29%), Positives = 48/89 (53%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A D+ H + K + ++ DVVV AG PR+PGM+RDDL NA ++R +
Sbjct: 40 ALDMGHAASATKTHTIVRVANEPSDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTV 99
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPLPLK 521
+ ++++ +++NP+++ V +K
Sbjct: 100 LSEVKPYIQESVLVMVSNPLDAMVYTAIK 128
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 55.6 bits (128), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+KDAD +VI AG P+KPG TR +L N I+R+IAL + ++ I I+ NPV+
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 55.2 bits (127), Expect = 1e-06
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +3
Query: 384 MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
MTRDDLF N IV+ + +IA N P A++ +I+NPVNSTVP+
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPI 43
Score = 40.3 bits (90), Expect = 0.037
Identities = 18/26 (69%), Positives = 21/26 (80%)
Frame = +2
Query: 509 IASEVLKKAGVYDPNRVLGVTTLDVV 586
IA+EVLK G YDP ++ GVTTLDVV
Sbjct: 43 IAAEVLKAKGKYDPKKLFGVTTLDVV 68
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 288 KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA 467
K+ G E++ A + DV +I AGVPRKPGM R DL N N ++ ++ + K
Sbjct: 71 KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGTYSNKD 130
Query: 468 I-VAIITNPVNSTVPLPLKCS 527
+ V ++ NP N+ + K S
Sbjct: 131 VRVVVVANPANTNAYVICKTS 151
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/86 (34%), Positives = 48/86 (55%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A DL+ ++T K+ + L AI A VV+ G KPG ++ +LF+ N VR++
Sbjct: 70 ACDLNEIDTRTKLKSFSC-KSLKNAIVGAHVVISTGGCQEKPGSSQRELFDKNLDNVRNV 128
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPL 512
A+ +A+ P+AI I PV + VP+
Sbjct: 129 AMFLAEFNPEAIYCIAKPPVEALVPM 154
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 54.0 bits (124), Expect = 3e-06
Identities = 26/64 (40%), Positives = 39/64 (60%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLP 515
D+D+VV+ AG ++ G TR DL NASI+ IA IA++ ++ I++NPV+
Sbjct: 72 DSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVDILTRAA 131
Query: 516 LKCS 527
LK S
Sbjct: 132 LKAS 135
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 54.0 bits (124), Expect = 3e-06
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Frame = +3
Query: 252 RAADLSHMNTPA----KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT-----RDDLF 404
+A D SH N A KVSG ++L+ A DVV++ AG + PG + RDDL
Sbjct: 44 KALDTSHTNVMAYSNCKVSGSNTYDDLAGA----DVVIVTAGFTKAPGKSDKEWNRDDLL 99
Query: 405 NTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
N I+ +I I +N P A + ++TNPV+ V L
Sbjct: 100 PLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQL 135
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/94 (30%), Positives = 58/94 (61%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 431
A DL++++T KVS PE+ L ++ A +V+I V + +++ +NA I+ D
Sbjct: 42 ALDLNYIDTKCKVSTCNHPEKCLEETLQGAKIVMI---VTDRTSNESNEVLKSNAIILSD 98
Query: 432 IALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRR 533
+ +I + +P+A++AI+ NP+NS +PL ++ ++
Sbjct: 99 LLPNIIKFSPQAMLAIVMNPINSLIPLTMEMYKK 132
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 53.6 bits (123), Expect = 4e-06
Identities = 26/69 (37%), Positives = 41/69 (59%)
Frame = +3
Query: 306 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 485
G ++L A+ A+ +VI AG PR+PGM+R DL NA I+ + I +AP + + I++
Sbjct: 183 GSDDL-VALAGAEYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVS 241
Query: 486 NPVNSTVPL 512
NP+ L
Sbjct: 242 NPLEEMTHL 250
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 53.6 bits (123), Expect = 4e-06
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 503
A +DAD+VVI AGVPRKPG +R DL N N I+ I + + I +NPV+
Sbjct: 68 ADARDADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVDIL 127
Query: 504 VPLPLKCS---RRRECTTRTACSASPL 575
+ + S R R T T+ + L
Sbjct: 128 TSMTQRLSGFPRHRVIGTGTSLDTARL 154
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 52.8 bits (121), Expect = 7e-06
Identities = 25/56 (44%), Positives = 38/56 (67%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+KD DVVVI AG P+KPG TR ++ NA I+ +IA +I ++ K + ++ NPV+
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD 126
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 52.8 bits (121), Expect = 7e-06
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = +3
Query: 300 HKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI 479
H G EL+ DA VV++ AG +KPG +R DL NA I R++ I + AP A++ +
Sbjct: 59 HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114
Query: 480 ITNPVN 497
+NPV+
Sbjct: 115 TSNPVD 120
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/56 (44%), Positives = 34/56 (60%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 500
KDAD+VVI AG P KPG +R D +A IV I + ++ I ++TNPV+S
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDS 129
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
+ +D+VVI AG PR PG R DL NA I+ +A +I AP + ++TNPV+
Sbjct: 71 VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVDVMTC 130
Query: 510 LPLKCS 527
+ LK S
Sbjct: 131 VALKYS 136
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/64 (42%), Positives = 39/64 (60%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 509
I DA VV+I AG +KPG TR DL NA+I+R I I + + I+ I++NPV+
Sbjct: 69 IADASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVDILTE 128
Query: 510 LPLK 521
+ L+
Sbjct: 129 VALR 132
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 51.2 bits (117), Expect = 2e-05
Identities = 21/56 (37%), Positives = 35/56 (62%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+KD DV+V+ AG RKPG TR DL N I +++ +I + ++ +++NPV+
Sbjct: 72 VKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVD 127
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/54 (44%), Positives = 33/54 (61%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
DAD+VVI AG P+KPG TR DL N +I + I + ++ K I + NPV+
Sbjct: 76 DADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVD 129
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/95 (37%), Positives = 46/95 (48%)
Frame = +3
Query: 237 ACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNA 416
A D AA LSH T + +K KDA VVI AG +KPG TR DL N
Sbjct: 62 AMDLNHAAPLSH-ETRVYLGDYKD-------CKDATAVVITAGKNQKPGETRMDLLKANI 113
Query: 417 SIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLK 521
SI ++I + + AI+ + TNPV+ LK
Sbjct: 114 SIFKEILREVTKYTKDAILLVATNPVDVLTYATLK 148
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
Frame = +3
Query: 252 RAADLSHMNTPA----KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT-----RDDLF 404
+A D SH N A KV+G ++L K ADVV++ AG + PG + RDDL
Sbjct: 37 KALDTSHSNVMAYSNCKVTGSNSYDDL----KGADVVIVTAGFTKAPGKSDKEWNRDDLL 92
Query: 405 NTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
N I+ +I I P A + ++TNPV+ V L
Sbjct: 93 PLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQL 128
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 50.4 bits (115), Expect = 3e-05
Identities = 25/53 (47%), Positives = 34/53 (64%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+DVVVI AG+PR+PG TR DL NA I+ DI S+ ++ I +NPV+
Sbjct: 72 SDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVD 124
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/65 (36%), Positives = 40/65 (61%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLP 515
+AD+VVI AG+ +KPG TR DL + N+ I +DI ++ + I + +NPV+ +
Sbjct: 73 NADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVDIMTYVT 132
Query: 516 LKCSR 530
+K S+
Sbjct: 133 MKYSK 137
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/55 (43%), Positives = 37/55 (67%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+DAD+VVI AG +KPG +R +L +I++ I ++ + AP AI +ITNPV+
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVD 129
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 50.0 bits (114), Expect = 5e-05
Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGH---KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 425
A D++H P VS G ++LS A DVV++ GV +KPG +R +L + NA +
Sbjct: 33 AEDIAHA-VPFSVSARIVAGGYDDLSGA----DVVILACGVSQKPGESRLELLSRNAEVF 87
Query: 426 RDIALSIAQNAPKAIVAIITNPVN 497
R + + + AP AI+ I +NPV+
Sbjct: 88 RAVVGDVTRAAPDAILLIASNPVD 111
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 50.0 bits (114), Expect = 5e-05
Identities = 27/81 (33%), Positives = 44/81 (54%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A D+S +G K A K AD++++ AG P+K G TR ++ N+ I++DI
Sbjct: 43 AMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMKDI 102
Query: 435 ALSIAQNAPKAIVAIITNPVN 497
AL I ++ +I+NPV+
Sbjct: 103 ALEIKKSGFNGFTIVISNPVD 123
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/55 (43%), Positives = 37/55 (67%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+DAD+VVI AG +KPG +R DL + NA I++ I +I ++ I+ I +NPV+
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVD 126
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Frame = +3
Query: 330 IKDADVVVI-PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 506
+ D+D+++I AGV K G TR D + NA I+R + + AP +IV II+NPV+
Sbjct: 71 LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLT 130
Query: 507 PLPLKCSRRRE 539
+ S R E
Sbjct: 131 RIAQATSTRAE 141
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 1/59 (1%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
AA+ +A ++V+ AG ++ P TR L NA I R+I + + ++AP AI+ + TNPV+
Sbjct: 67 AALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVD 125
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 48.0 bits (109), Expect = 2e-04
Identities = 23/63 (36%), Positives = 37/63 (58%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
K AD++VI AG+ +KPG TR L NA I+++I +I + + + +NPV+ L
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVLAEL 129
Query: 513 PLK 521
L+
Sbjct: 130 VLQ 132
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 47.6 bits (108), Expect = 2e-04
Identities = 22/63 (34%), Positives = 36/63 (57%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPL 518
AD+VVI AG+PRK R L + NA+++ D+ +P I+ ++TNP++ L
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAY 127
Query: 519 KCS 527
+ S
Sbjct: 128 QVS 130
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 47.2 bits (107), Expect = 3e-04
Identities = 23/51 (45%), Positives = 33/51 (64%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 491
AD+VVI AG + G TR D+ NA I +IA I + APKA++ +++NP
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 46.8 bits (106), Expect = 4e-04
Identities = 23/57 (40%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +3
Query: 333 KDADVVVIPAGVP-RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 500
KD+DV++ A VP R P TR ++ N I+RD +A+ +P AIV +++NPV++
Sbjct: 67 KDSDVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDA 123
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 46.8 bits (106), Expect = 4e-04
Identities = 27/99 (27%), Positives = 51/99 (51%)
Frame = +3
Query: 201 SSGDQAGFIRHSACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 380
S+G A + +SA DL+H + G ++++ A +VV+ AG + P
Sbjct: 42 SAGTLALYDTNSAKVRAEVLDLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHP 100
Query: 381 GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
G +R DL N ++ + + + +++P A+V +TNPV+
Sbjct: 101 GQSRLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVD 139
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Frame = +3
Query: 252 RAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG-----MTRDDLFNTNA 416
+A DL H A A+++ ADVV+I AG+ + G +R DL N
Sbjct: 49 KALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSDQEWSRKDLLPVNV 108
Query: 417 SIVRDIALSIAQNAPKAIVAIITNPVNSTV 506
I+R++ +I Q P A V ITNP++ V
Sbjct: 109 KILREVGAAIKQFCPHAFVINITNPLDVMV 138
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 491
KDAD++VI AG P++PG TR +L N+ I++ IA +I + + I +NP
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNP 124
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 46.4 bits (105), Expect = 6e-04
Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +3
Query: 315 ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNP 491
++ A+ DA +V G PRK GMTR+DL NA I + I P V II NP
Sbjct: 67 DIKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNP 126
Query: 492 VNST 503
+ T
Sbjct: 127 ADIT 130
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/53 (41%), Positives = 31/53 (58%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
A +VV+ AG + PG +R DL NA I RDI ++ Q A + + TNPV+
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVD 121
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/54 (40%), Positives = 33/54 (61%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
DAD+VVI A +P G TR D+ A I+ +I +I ++ I+ +ITNPV+
Sbjct: 73 DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVD 126
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/44 (47%), Positives = 30/44 (68%)
Frame = +3
Query: 390 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLK 521
RDDL N+ I+RD+ +I + AP+A V +ITNP++ V L LK
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMVHLMLK 186
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/55 (38%), Positives = 32/55 (58%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
K++D+V+ AG RK G +R++L N SI+ D A I + I+TNPV+
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVD 122
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 45.2 bits (102), Expect = 0.001
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +3
Query: 321 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAIITNPVN 497
+ A KDADV ++ PR PGM R DL N I +I + A P V ++ NP N
Sbjct: 77 AVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136
Query: 498 STVPLPLKCSRR 533
+ + +K + +
Sbjct: 137 TNAYIAMKSAMK 148
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 327 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNST 503
A KDADV + +PRKPGM R DL N I + + A + V ++ NP N+
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNTN 138
Query: 504 -VPLPLKCSR 530
L +C++
Sbjct: 139 CATLAHQCTK 148
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/86 (26%), Positives = 44/86 (51%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 434
A D +H +T +V + + +S ++K AD+VV+ M+ L V +
Sbjct: 62 ALDFNHFDTRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKL 121
Query: 435 ALSIAQNAPKAIVAIITNPVNSTVPL 512
A + A+ APKA++ + P++ T+P+
Sbjct: 122 AETCAKYAPKAVIVVAVTPISVTLPI 147
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Frame = +3
Query: 237 ACDPRRAADLSHM-NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTN 413
A D R A L++M NT K + + I A V+P+ P R L TN
Sbjct: 45 ALDWRHATALTYMPNTSVKAGDYSECADADVIICAAGPSVLPSEKDEMPD--RAGLARTN 102
Query: 414 ASIVRDIALSIAQNAPKAIVAIITNPVNSTV 506
A++VR++ I + +A++ ITNP+++ V
Sbjct: 103 AAVVREVMAGITKYTKEAVIIFITNPLDTIV 133
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
KDA+++VI AG +PG T D L TNA I+ + I + +A++ +ITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD 128
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/55 (40%), Positives = 30/55 (54%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
KDAD+V I AG ++ G TR DL N I ++I + + I I TNPV+
Sbjct: 75 KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIFLIATNPVD 129
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 42.7 bits (96), Expect = 0.007
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
A + A V VI AG ++PG TR L + N +I + I + ++ P ++ I TNPV+
Sbjct: 73 ADCRGAAVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVD 130
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 42.7 bits (96), Expect = 0.007
Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +3
Query: 321 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVA-IITNPVN 497
S +D DV V G PRKPGM R DL N +I + ++ A K + ++ NP N
Sbjct: 115 SILFQDVDVAVFIGGFPRKPGMERKDLLTINGNIFKKQGQALDTVAKKTCKSLVVANPAN 174
Query: 498 S 500
+
Sbjct: 175 T 175
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 42.7 bits (96), Expect = 0.007
Identities = 22/55 (40%), Positives = 30/55 (54%)
Frame = +3
Query: 333 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
K+AD+V I AG +KPG TR DL N I + + + + I I TNPV+
Sbjct: 73 KEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIFLIATNPVD 127
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 42.7 bits (96), Expect = 0.007
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Frame = +3
Query: 255 AADLSHM----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 422
A DLSH NT KV + G E KD D+V+I AG KPG +R D +A I
Sbjct: 47 AMDLSHCINFTNTRTKV--YAGSYE---DCKDMDIVIITAGPAPKPGQSRLDTLGASAKI 101
Query: 423 VRDIALSIAQNAPKAIVAIITNPVNSTVPLPLKCS---RRRECTTRTACSASPLWT 581
+ + + ++ I + +NPV+ K S R R T T+ +S L T
Sbjct: 102 MESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTSLDSSRLRT 157
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 41.9 bits (94), Expect = 0.012
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Frame = +3
Query: 291 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI 470
V+G +++ A KD DV + PRK GM R DL N I +++ A K +
Sbjct: 46 VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105
Query: 471 -VAIITNPVNS 500
V ++ NP N+
Sbjct: 106 KVLVVGNPANT 116
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 41.5 bits (93), Expect = 0.016
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +3
Query: 315 ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNP 491
++ A+ A +V G RK GMTR+DL NA I I Q P V ++ NP
Sbjct: 67 DIKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNP 126
Query: 492 VNST 503
+ T
Sbjct: 127 ADIT 130
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 41.5 bits (93), Expect = 0.016
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK--AIVAIITNPVN 497
I D+DV+ I AG+ RKP +R DL N N + I S+ K AI +++NPV+
Sbjct: 66 IPDSDVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVD 123
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 40.3 bits (90), Expect = 0.037
Identities = 25/57 (43%), Positives = 31/57 (54%)
Frame = -2
Query: 355 MTTTSASLMAADSSSGPLWPLTLAGVFMWERSAARRGSQALCRIKPAWSPEDSASVE 185
M TTS S AA SS+ P +P T A VF E SAA G L + +PA P+ + E
Sbjct: 1 MITTSQSFSAAPSSASPAYPFTCAAVFTCETSAATPGRIHLHQ-QPARLPDPTRGAE 56
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 40.3 bits (90), Expect = 0.037
Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +3
Query: 321 SAAIKDADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+AA++DAD+ V AG PR P + TR DL N + + + + + P +++ +TNP++
Sbjct: 59 TAAMRDADIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMD 116
Query: 498 S 500
+
Sbjct: 117 A 117
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 39.9 bits (89), Expect = 0.049
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +3
Query: 393 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 506
DDL + N S+ + +A ++ Q+AP A V + TNP++S V
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIV 53
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 39.5 bits (88), Expect = 0.065
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Frame = +3
Query: 285 AKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK 464
A + H P A KD D ++ PR PGM R DL NA I ++ A +
Sbjct: 69 AGIEAHSDP---MTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASR 125
Query: 465 AI-VAIITNPVNSTVPLPLK 521
+ V ++ NP N+ + +K
Sbjct: 126 NVKVLVVGNPANTNAYIAMK 145
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 39.5 bits (88), Expect = 0.065
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +3
Query: 243 DPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 422
D A SH NT V ++ +DA +V I AG +KPG TR DL N +I
Sbjct: 59 DLNHAVPWSHHNTRVTVGTYED-------CRDAAMVCICAGAAQKPGETRLDLVAKNTAI 111
Query: 423 VRDIALSIAQNAPKAIVAIITNPVN 497
+ I + + I + +NPV+
Sbjct: 112 FKTIVGDVMSHGFNGIFLVASNPVD 136
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 291 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKA 467
+SG + + A KD D ++ PRK GM R +L + N I + +I ++A P
Sbjct: 66 LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQIQGAAINEHAKPTC 125
Query: 468 IVAIITNPVNS 500
+ +I NP N+
Sbjct: 126 RILVIGNPANT 136
>UniRef50_A7SAG3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 843
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Frame = +3
Query: 195 AESSGDQAG-FIRHSACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 371
A++S Q G F ++ A P+ A+ H P + GH G + S V +P G+P
Sbjct: 729 AQASPSQQGQFFQYQAMPPQMMANPQHPGIPHQPQGHMGAQSPSQVAPPQQFVYLPQGMP 788
Query: 372 RKPGM 386
+ GM
Sbjct: 789 QPGGM 793
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 38.3 bits (85), Expect = 0.15
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKP-GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
+KD D + I AG P+K G TR L N I++ IA I ++ + I +NPV+
Sbjct: 69 LKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVD 125
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 38.3 bits (85), Expect = 0.15
Identities = 17/53 (32%), Positives = 29/53 (54%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
AD+VVI AG ++ G R L N +++ I + P A++ ++ NPV+
Sbjct: 71 ADIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVD 123
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 37.9 bits (84), Expect = 0.20
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +3
Query: 255 AADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVP-RKPGMTRDDLFNTNASIVRD 431
AADLSH++T KV + A ++DA ++++ G RD A +R
Sbjct: 60 AADLSHIDTLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRR 119
Query: 432 IALSIAQNAPKAIVAIITNPVNSTVP 509
+ ++A + VA++++PVN+ P
Sbjct: 120 VMAAVASSDTTGNVAVVSSPVNALTP 145
Score = 34.7 bits (76), Expect = 1.9
Identities = 13/24 (54%), Positives = 20/24 (83%)
Frame = +2
Query: 515 SEVLKKAGVYDPNRVLGVTTLDVV 586
+E+LK +G +DP ++ GVTTLDV+
Sbjct: 148 AELLKASGKFDPRKLFGVTTLDVI 171
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Frame = +3
Query: 306 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAII 482
G +L A +D DV + P+KP D F NASI + +++ A P V +I
Sbjct: 69 GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128
Query: 483 TNPVNS 500
P N+
Sbjct: 129 GMPTNT 134
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/58 (36%), Positives = 30/58 (51%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPL 512
ADVV+I AGV PG T SI++ I + P AI+ ++ NPV++ L
Sbjct: 70 ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTL 127
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 37.1 bits (82), Expect = 0.35
Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +3
Query: 324 AAIKDADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
A +KDAD + AG R P + TR DLF+ N I ++ + + + K IV +TNP++
Sbjct: 59 ADLKDADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESSELLKGFSGKLIV--VTNPMD 115
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 37.1 bits (82), Expect = 0.35
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +3
Query: 336 DADVVVIPAGVPRKPGMTRDDLF--NTNASIVRDIALSIAQNAPKAIVAIITNPVN 497
DA ++VI AG KP D L +TN + I +I + AI+ ++TNPV+
Sbjct: 74 DAQIIVITAGPSLKPDDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD 129
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 36.7 bits (81), Expect = 0.46
Identities = 21/85 (24%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Frame = +3
Query: 261 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDL-FNTNASIVRDIA 437
D+ H++T + H + +++ D+V + G + F +++ V+ +A
Sbjct: 27 DMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMDETDFMMGNKGPFMQFVNSSNYVKSVA 85
Query: 438 LSIAQNAPKAIVAIITNPVNSTVPL 512
+ PKA+VA+ T+PV +T+PL
Sbjct: 86 ECMINVCPKALVAVFTHPVTATLPL 110
>UniRef50_UPI00015537B7 Cluster: PREDICTED: hypothetical protein;
n=1; Mus musculus|Rep: PREDICTED: hypothetical protein -
Mus musculus
Length = 217
Score = 36.7 bits (81), Expect = 0.46
Identities = 32/112 (28%), Positives = 48/112 (42%)
Frame = -2
Query: 382 PGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAARRGSQALCRIKPAWSPE 203
PGLRG G++ +A+ GP + + G R GS+ ++P W+
Sbjct: 63 PGLRGPGTGISRPAAAAEGGGLERGPALVIRVPG-----PGGGRAGSER--EVRPPWN-L 114
Query: 202 DSASVEGPKAGRYHRRHQRPPL*SSSVMWWKSSLHHFVQQGRQVLGRGRTFS 47
D A + G + RR P L + WW S+ G QV GRG++ S
Sbjct: 115 DIARGKPRAGGLWRRRVAGPALVAGPGAWW--SVGGVALGGCQVGGRGKSGS 164
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 36.7 bits (81), Expect = 0.46
Identities = 19/56 (33%), Positives = 31/56 (55%)
Frame = +3
Query: 339 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 506
AD+VVI AG +K G +R L N +I+ I S+ + ++ ++ NPV+ V
Sbjct: 73 ADIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILV 128
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 36.7 bits (81), Expect = 0.46
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Frame = +3
Query: 318 LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI--VRDIALSIAQNAPKAIVAIITNP 491
L+ A D + VPR PGM R DL N I ++ AL+ A A + ++ NP
Sbjct: 76 LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134
Query: 492 VNSTVPLPLKCSRR 533
VN+ + +K + R
Sbjct: 135 VNTNCWIAMKHAPR 148
>UniRef50_A7P3R2 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 253
Score = 36.3 bits (80), Expect = 0.61
Identities = 25/102 (24%), Positives = 36/102 (35%)
Frame = -1
Query: 479 DGHNSFGCILSNGQSNVTDNGSISVE*VITGHSRFTGYSCWDDYNISIFDGC**LLRSLV 300
DG CI+ + S + + V T G D YN+S+ DGC S++
Sbjct: 143 DGSGLGSCIIGDCGSGTIECNGVGVALPATLAEFTLGTGGQDFYNVSLIDGC---NLSMI 199
Query: 299 AADLGWGVHVGKVGCTPGVTGAMSYKASLVTRGFCFSRRAKG 174
GW GCT + K + C S +G
Sbjct: 200 VERSGWSRMCASTGCTVDLNQGCPAKLKVEDGNVCRSEHVRG 241
>UniRef50_A3ZUQ5 Cluster: Two component response regulator; n=1;
Blastopirellula marina DSM 3645|Rep: Two component
response regulator - Blastopirellula marina DSM 3645
Length = 467
Score = 35.9 bits (79), Expect = 0.80
Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = +3
Query: 249 RRAAD-LSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM---TRDDLFNTNA 416
RR A+ L+ A V+G E + A ++ D+VV+ + PR + +R D T A
Sbjct: 19 RRTAEFLNACRLEAYVAGDADQAEWALASREPDIVVVDSAAPRAAAVLQSSRRDRHTTQA 78
Query: 417 SIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLKCSRRRECTTRTACSASPLWT*SRCH 596
+ L ++P+ I I + +P PL R E R +A L SR H
Sbjct: 79 YVY--AILITDSDSPERIFDAIAGGADDVIPRPL---RFTELLVRIRAAARSLEVESRLH 133
Query: 597 LR 602
R
Sbjct: 134 RR 135
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 35.1 bits (77), Expect = 1.4
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Frame = +3
Query: 309 PEELSAAIKDADVVVIPAGVPR-KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 485
P L KDADVVVI A +P K R L NA +++ A + K IV +
Sbjct: 62 PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121
Query: 486 NP 491
NP
Sbjct: 122 NP 123
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 34.3 bits (75), Expect = 2.4
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPG------MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 491
+KDADVV I A +P P R L N I+ +IAL + + K + I TNP
Sbjct: 68 LKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSIIPTNP 127
>UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 492
Score = 33.9 bits (74), Expect = 3.2
Identities = 18/67 (26%), Positives = 32/67 (47%)
Frame = +3
Query: 312 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 491
++LS A+ D D VV G +D+ S ++D+ LSI +N ++ +P
Sbjct: 173 DDLSLAVADCDGVVYVNGPDTSEISNENDIERLFVSSIQDVFLSIKRNGKSVRRVVLISP 232
Query: 492 VNSTVPL 512
+S P+
Sbjct: 233 ASSIFPV 239
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 33.9 bits (74), Expect = 3.2
Identities = 21/62 (33%), Positives = 28/62 (45%)
Frame = +3
Query: 342 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPLPLK 521
D+VVI AG G T D N SIVR I + ++ I+ NPV+ L +
Sbjct: 77 DIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSLAKE 136
Query: 522 CS 527
S
Sbjct: 137 LS 138
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 33.5 bits (73), Expect = 4.3
Identities = 20/64 (31%), Positives = 32/64 (50%)
Frame = +3
Query: 306 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 485
G ++ S A +DA V VI G L N +I +D+ + + AP +I+ I+T
Sbjct: 91 GTKDYSLA-RDATVCVITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVT 149
Query: 486 NPVN 497
PV+
Sbjct: 150 APVD 153
>UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Apis
mellifera|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Apis mellifera
Length = 221
Score = 33.5 bits (73), Expect = 4.3
Identities = 14/38 (36%), Positives = 25/38 (65%)
Frame = +2
Query: 515 SEVLKKAGVYDPNRVLGVTTLDVVALPPSSARINGVDP 628
SE+ K AG +DP+R++G T LD + + +A + ++P
Sbjct: 29 SEIYKLAGWWDPDRIIGSTALDRMRMEALTANLLDLNP 66
>UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein
precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
Putative uncharacterized protein precursor - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 303
Score = 33.5 bits (73), Expect = 4.3
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +3
Query: 351 VIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI-ITNPVNS 500
++P G P KP T D+ +T ++ + L +NA KAI+ + NPVN+
Sbjct: 116 LVPEG-PSKPNPTAQDIVSTLGNLNLNSILVTRENADKAIIEVSFANPVNT 165
>UniRef50_A5FD47 Cluster: RagB/SusD domain protein precursor; n=1;
Flavobacterium johnsoniae UW101|Rep: RagB/SusD domain
protein precursor - Flavobacterium johnsoniae UW101
Length = 507
Score = 33.5 bits (73), Expect = 4.3
Identities = 19/52 (36%), Positives = 31/52 (59%)
Frame = +3
Query: 252 RAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFN 407
R +D+ MN+ A ++G G ++A+ + V AG+P K +TRD+LFN
Sbjct: 376 RYSDILLMNSEAILAG-AGSTTSASALSSFNEVRARAGLPAKTVLTRDELFN 426
>UniRef50_Q603D8 Cluster: Putative S-layer protein; n=2;
Proteobacteria|Rep: Putative S-layer protein -
Methylococcus capsulatus
Length = 353
Score = 33.1 bits (72), Expect = 5.7
Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 9/146 (6%)
Frame = +3
Query: 51 NVLPRPKTCRPCCTKWCKELFHHITEEL*SGGRWCRRWYRPAFGPSTEAESSGDQAGFIR 230
N L +CR T EL H + + +G + FGP +G + GF+R
Sbjct: 52 NELGIDSSCRHAVTM-TGELTDHFEDRM-TGVQTLTATMLRRFGPEGILVFAG-RVGFLR 108
Query: 231 HSACDPRRAADLSHMNTPAKVS--GHKGPEE---LSAAIKDADVVVIPAGVPRKPGMTRD 395
A PR A D++ N A S H+ E + D+VV+ G R G T
Sbjct: 109 ADAVQPRHALDVASANWLASASLIAHRLREPALFVDIGSTTTDLVVLGGGEVRARGYTDY 168
Query: 396 DLFNTN----ASIVRDIALSIAQNAP 461
D + +VR A+++A P
Sbjct: 169 DRLRYDELIYTGVVRTSAMALADELP 194
>UniRef50_Q1DER6 Cluster: Putative uncharacterized protein; n=1;
Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
protein - Myxococcus xanthus (strain DK 1622)
Length = 640
Score = 33.1 bits (72), Expect = 5.7
Identities = 20/53 (37%), Positives = 27/53 (50%)
Frame = +3
Query: 213 QAGFIRHSACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 371
+AG +R +P L+ MNT A+ +G G E SA A V +PAG P
Sbjct: 420 RAGLLREP--EPETGRLLARMNTEARTAGDVGAERASAYALGAVVSRLPAGSP 470
>UniRef50_A4E858 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 357
Score = 33.1 bits (72), Expect = 5.7
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Frame = -2
Query: 439 KAMSRTMEALVLNR-SSRVIPGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWER 263
+A RT+ A+ L + I ++ + +A L AA S G + + L G +MW R
Sbjct: 187 RAQQRTLGAISLPKVRDSYIQTVKDAGLYVDAETADL-AARKSMGHPYMVQLVGYYMW-R 244
Query: 262 SAARRGSQALCR 227
SA RRGSQ + R
Sbjct: 245 SAVRRGSQVIER 256
>UniRef50_Q6ZB96 Cluster: Putative uncharacterized protein
OJ1113_A10.2; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJ1113_A10.2 - Oryza sativa subsp. japonica (Rice)
Length = 106
Score = 33.1 bits (72), Expect = 5.7
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Frame = -2
Query: 304 LWPLTLAG---VFMWERSAARRGSQALCRIKPAWSPEDSASVEGPKAGRYHRRHQRPPL* 134
+W +T G + +R ARR AW+ ED+A + + G + RPP
Sbjct: 1 MWVVTTIGDRAIVEVDRRGARRTQPLAMSSDMAWTVEDAAISDELRRGAWMTERTRPPPL 60
Query: 133 SSSVMW 116
SS V W
Sbjct: 61 SSDVAW 66
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 33.1 bits (72), Expect = 5.7
Identities = 17/62 (27%), Positives = 36/62 (58%), Gaps = 6/62 (9%)
Frame = +3
Query: 330 IKDADVVVIPAGVPRKPGMTRDD------LFNTNASIVRDIALSIAQNAPKAIVAIITNP 491
IKD+ VVV+ V + D+ ++ +N +++++A S+ ++ P+A V + T+P
Sbjct: 72 IKDSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSP 131
Query: 492 VN 497
V+
Sbjct: 132 VD 133
>UniRef50_A6W5Y8 Cluster: Putative transcriptional regulator, MerR
family; n=1; Kineococcus radiotolerans SRS30216|Rep:
Putative transcriptional regulator, MerR family -
Kineococcus radiotolerans SRS30216
Length = 356
Score = 32.7 bits (71), Expect = 7.5
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Frame = -2
Query: 571 GDAEHAVRVVHSRLLEHFRGNGTVELTGFVMMATIALGAF*AMDKAMSRTMEALVLNRSS 392
GDA+ AV + R E RG G V+ +A AM A++RT+ AL +
Sbjct: 174 GDADWAVSSLADRFSEEVRGRGVAPAWDAVLSPALATRDA-AMHAAVARTLAALPVATGE 232
Query: 391 R--VIPGLRGTPAGMTTTSASLMAA 323
R ++ GL AG L AA
Sbjct: 233 RAVLLAGLHDPAAGAPRGPVLLAAA 257
>UniRef50_A3AIZ4 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 547
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/44 (34%), Positives = 18/44 (40%)
Frame = -2
Query: 271 WERSAARRGSQALCRIKPAWSPEDSASVEGPKAGRYHRRHQRPP 140
W A GS+ + WSP S GR RR +RPP
Sbjct: 459 WRERMAAAGSRRRRSARRRWSPPGRCSASTTAGGRCQRRRRRPP 502
>UniRef50_O26630 Cluster: UDP-N-acetylmuramyl tripeptide synthetase
related protein; n=1; Methanothermobacter
thermautotrophicus str. Delta H|Rep: UDP-N-acetylmuramyl
tripeptide synthetase related protein - Methanobacterium
thermoautotrophicum
Length = 682
Score = 32.7 bits (71), Expect = 7.5
Identities = 20/40 (50%), Positives = 24/40 (60%)
Frame = +3
Query: 243 DPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA 362
D R L +NT A SG G E++A +KDAD VVIPA
Sbjct: 574 DLRGKGRLIVVNTVASESGIDGDREIAAILKDAD-VVIPA 612
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 7.5
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -2
Query: 148 RPPL*SSSVMWWKSSLHHFVQQ 83
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
>UniRef50_A0JM83 Cluster: Uncharacterized protein C1orf174 homolog;
n=3; Xenopus|Rep: Uncharacterized protein C1orf174
homolog - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 227
Score = 32.7 bits (71), Expect = 7.5
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +3
Query: 198 ESSGDQAGFIRHSACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVV-IPAGVPR 374
+ SGD GFI + +P + ++ +P P L ++AD++ +P VP
Sbjct: 132 DDSGDGTGFIHKTCSEPSKLREIYLNGSPFVDEDSNQPMPLGLFFENADLMQDLPPAVPS 191
Query: 375 KPGMTRDDLFN 407
M+R +L N
Sbjct: 192 CASMSRRELRN 202
>UniRef50_Q0G767 Cluster: Putative uncharacterized protein; n=1;
Fulvimarina pelagi HTCC2506|Rep: Putative
uncharacterized protein - Fulvimarina pelagi HTCC2506
Length = 284
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/61 (27%), Positives = 29/61 (47%)
Frame = +3
Query: 177 FGPSTEAESSGDQAGFIRHSACDPRRAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVI 356
+G S + SG+ A FI+ + P +A + ++ + G PE + A+ D D V
Sbjct: 138 WGSSLHFDESGE-AVFIKRALTHPEKARYMEALSKGFSIHGSNAPESTTKAVSDEDKAVP 196
Query: 357 P 359
P
Sbjct: 197 P 197
>UniRef50_Q01UG3 Cluster: Putative uncharacterized protein
precursor; n=3; Solibacter usitatus Ellin6076|Rep:
Putative uncharacterized protein precursor - Solibacter
usitatus (strain Ellin6076)
Length = 1185
Score = 32.3 bits (70), Expect = 9.9
Identities = 18/39 (46%), Positives = 23/39 (58%)
Frame = -2
Query: 442 DKAMSRTMEALVLNRSSRVIPGLRGTPAGMTTTSASLMA 326
D A++ M A V N ++P GTPAG TTT A L+A
Sbjct: 887 DTALNTAMSASVANPFFGLVP--TGTPAGATTTVAQLLA 923
>UniRef50_A4X7T9 Cluster: Putative uncharacterized protein; n=1;
Salinispora tropica CNB-440|Rep: Putative
uncharacterized protein - Salinispora tropica CNB-440
Length = 166
Score = 32.3 bits (70), Expect = 9.9
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 10/96 (10%)
Frame = -2
Query: 403 NRSSRVIPGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSA--ARRGSQALC 230
NRS+ P RG+PAG T+ WP TL G W++++ RR +
Sbjct: 17 NRSASASPAARGSPAGARQTTG---PPSPQRAARWPTTLFGT-DWKKNSGPGRRSAATAA 72
Query: 229 R--IKPAWSPEDSASV------EGPKAGRYHRRHQR 146
R + A SP S G A RY RR R
Sbjct: 73 RTYVALASSPVGLTSTIAVRSPSGAGAARYARRRHR 108
>UniRef50_A3TJH6 Cluster: Putative DNA-binding protein; n=1;
Janibacter sp. HTCC2649|Rep: Putative DNA-binding
protein - Janibacter sp. HTCC2649
Length = 258
Score = 32.3 bits (70), Expect = 9.9
Identities = 19/54 (35%), Positives = 22/54 (40%)
Frame = -2
Query: 331 MAADSSSGPLWPLTLAGVFMWERSAARRGSQALCRIKPAWSPEDSASVEGPKAG 170
+A G L P AG E S RG+ L R P+ SP S GP G
Sbjct: 45 LAGRGEGGALGPRAAAGA---EPSGVSRGTSTLSRASPSGSPTTEKSTAGPSPG 95
>UniRef50_A2ZQ03 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 652
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/50 (34%), Positives = 27/50 (54%)
Frame = -2
Query: 289 LAGVFMWERSAARRGSQALCRIKPAWSPEDSASVEGPKAGRYHRRHQRPP 140
L G W+ +A RR + CR++P P + E P++GR+ H+R P
Sbjct: 10 LVGGRKWDWAAQRRNIRGRCRMQPPERPGEQG--ERPRSGRF-TGHERQP 56
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 697,358,645
Number of Sequences: 1657284
Number of extensions: 15502405
Number of successful extensions: 48043
Number of sequences better than 10.0: 155
Number of HSP's better than 10.0 without gapping: 45414
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 48006
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46466611856
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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