Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0149
(677 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 80 8e-15
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 80 8e-15
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 80 8e-15
AB208932-1|BAD92169.1| 471|Homo sapiens hydroxysteroid (17-beta... 80 8e-15
Y11393-1|CAA72203.1| 74|Homo sapiens peroxisomal multifunction... 57 5e-08
AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related ... 31 3.8
X64877-1|CAA46096.1| 270|Homo sapiens serum protein protein. 31 5.0
BC022283-1|AAH22283.1| 270|Homo sapiens complement factor H-rel... 31 5.0
BC016966-1|AAH16966.1| 262|Homo sapiens ANGEL2 protein protein. 31 5.0
AL592449-5|CAH71920.1| 544|Homo sapiens novel protein protein. 31 5.0
AL139418-1|CAI21979.1| 270|Homo sapiens complement factor H-rel... 31 5.0
AK125200-1|BAC86082.1| 146|Homo sapiens protein ( Homo sapiens ... 31 5.0
BX538130-1|CAD98031.1| 986|Homo sapiens hypothetical protein pr... 30 6.6
BC060862-1|AAH60862.1| 985|Homo sapiens ring finger protein 111... 30 6.6
BC010369-1|AAH10369.1| 137|Homo sapiens RNF111 protein protein. 30 6.6
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 79.8 bits (188), Expect = 8e-15
Identities = 36/56 (64%), Positives = 42/56 (75%)
Frame = +1
Query: 508 SLYRMSGDLNPLHIDPNVATASGHKKPILHGLASLGFSARHVLAKFGGNDSSNVKA 675
+LYR+SGD NPLHIDPN A+ +G KPILHGL + GFSAR VL +F ND S KA
Sbjct: 503 ALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKA 558
Score = 73.3 bits (172), Expect = 7e-13
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +3
Query: 3 TYDYNAKDLVIYALGVGASVENPTDLKFLYESHENFSPLPSFFILAGM-CMEAPIVANAM 179
+Y Y + ++YALGVGAS+++P DLKF+YE +FS LP+F ++ G M +A
Sbjct: 336 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI- 394
Query: 180 PPGKFADFTNVLHGEQYIEFVGDFP 254
PG +F VLHGEQY+E P
Sbjct: 395 -PGLSINFAKVLHGEQYLELYKPLP 418
Score = 65.7 bits (153), Expect = 1e-10
Identities = 32/82 (39%), Positives = 44/82 (53%)
Frame = +2
Query: 263 GVFTTRCYVVDILDKGSSAVAIVNSEIFQNKQLVCRTQQHIFVLGQGGFGGPRNSKNAIG 442
G V D+LDKGS V I++ + K+L+C Q +F++G GGFGG R S
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 443 VGNAPKRNPDAVVEQRTAEDQA 508
P R PDAV+ T+ +QA
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQA 502
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 79.8 bits (188), Expect = 8e-15
Identities = 36/56 (64%), Positives = 42/56 (75%)
Frame = +1
Query: 508 SLYRMSGDLNPLHIDPNVATASGHKKPILHGLASLGFSARHVLAKFGGNDSSNVKA 675
+LYR+SGD NPLHIDPN A+ +G KPILHGL + GFSAR VL +F ND S KA
Sbjct: 503 ALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKA 558
Score = 73.3 bits (172), Expect = 7e-13
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +3
Query: 3 TYDYNAKDLVIYALGVGASVENPTDLKFLYESHENFSPLPSFFILAGM-CMEAPIVANAM 179
+Y Y + ++YALGVGAS+++P DLKF+YE +FS LP+F ++ G M +A
Sbjct: 336 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI- 394
Query: 180 PPGKFADFTNVLHGEQYIEFVGDFP 254
PG +F VLHGEQY+E P
Sbjct: 395 -PGLSINFAKVLHGEQYLELYKPLP 418
Score = 65.7 bits (153), Expect = 1e-10
Identities = 32/82 (39%), Positives = 44/82 (53%)
Frame = +2
Query: 263 GVFTTRCYVVDILDKGSSAVAIVNSEIFQNKQLVCRTQQHIFVLGQGGFGGPRNSKNAIG 442
G V D+LDKGS V I++ + K+L+C Q +F++G GGFGG R S
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 443 VGNAPKRNPDAVVEQRTAEDQA 508
P R PDAV+ T+ +QA
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQA 502
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 79.8 bits (188), Expect = 8e-15
Identities = 36/56 (64%), Positives = 42/56 (75%)
Frame = +1
Query: 508 SLYRMSGDLNPLHIDPNVATASGHKKPILHGLASLGFSARHVLAKFGGNDSSNVKA 675
+LYR+SGD NPLHIDPN A+ +G KPILHGL + GFSAR VL +F ND S KA
Sbjct: 503 ALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKA 558
Score = 73.3 bits (172), Expect = 7e-13
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +3
Query: 3 TYDYNAKDLVIYALGVGASVENPTDLKFLYESHENFSPLPSFFILAGM-CMEAPIVANAM 179
+Y Y + ++YALGVGAS+++P DLKF+YE +FS LP+F ++ G M +A
Sbjct: 336 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI- 394
Query: 180 PPGKFADFTNVLHGEQYIEFVGDFP 254
PG +F VLHGEQY+E P
Sbjct: 395 -PGLSINFAKVLHGEQYLELYKPLP 418
Score = 65.7 bits (153), Expect = 1e-10
Identities = 32/82 (39%), Positives = 44/82 (53%)
Frame = +2
Query: 263 GVFTTRCYVVDILDKGSSAVAIVNSEIFQNKQLVCRTQQHIFVLGQGGFGGPRNSKNAIG 442
G V D+LDKGS V I++ + K+L+C Q +F++G GGFGG R S
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 443 VGNAPKRNPDAVVEQRTAEDQA 508
P R PDAV+ T+ +QA
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQA 502
>AB208932-1|BAD92169.1| 471|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 variant protein.
Length = 471
Score = 79.8 bits (188), Expect = 8e-15
Identities = 36/56 (64%), Positives = 42/56 (75%)
Frame = +1
Query: 508 SLYRMSGDLNPLHIDPNVATASGHKKPILHGLASLGFSARHVLAKFGGNDSSNVKA 675
+LYR+SGD NPLHIDPN A+ +G KPILHGL + GFSAR VL +F ND S KA
Sbjct: 258 ALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKA 313
Score = 73.3 bits (172), Expect = 7e-13
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +3
Query: 3 TYDYNAKDLVIYALGVGASVENPTDLKFLYESHENFSPLPSFFILAGM-CMEAPIVANAM 179
+Y Y + ++YALGVGAS+++P DLKF+YE +FS LP+F ++ G M +A
Sbjct: 91 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI- 149
Query: 180 PPGKFADFTNVLHGEQYIEFVGDFP 254
PG +F VLHGEQY+E P
Sbjct: 150 -PGLSINFAKVLHGEQYLELYKPLP 173
Score = 65.7 bits (153), Expect = 1e-10
Identities = 32/82 (39%), Positives = 44/82 (53%)
Frame = +2
Query: 263 GVFTTRCYVVDILDKGSSAVAIVNSEIFQNKQLVCRTQQHIFVLGQGGFGGPRNSKNAIG 442
G V D+LDKGS V I++ + K+L+C Q +F++G GGFGG R S
Sbjct: 176 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 235
Query: 443 VGNAPKRNPDAVVEQRTAEDQA 508
P R PDAV+ T+ +QA
Sbjct: 236 AVAIPNRPPDAVLTDTTSLNQA 257
>Y11393-1|CAA72203.1| 74|Homo sapiens peroxisomal multifunctional
protein 2 protein.
Length = 74
Score = 57.2 bits (132), Expect = 5e-08
Identities = 23/47 (48%), Positives = 35/47 (74%)
Frame = +3
Query: 3 TYDYNAKDLVIYALGVGASVENPTDLKFLYESHENFSPLPSFFILAG 143
+Y Y + ++YALGVGAS+++P DLKF+YE +FS LP+F ++ G
Sbjct: 12 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIG 58
>AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related tumor
marker CA125 protein.
Length = 22152
Score = 31.1 bits (67), Expect = 3.8
Identities = 29/128 (22%), Positives = 50/128 (39%), Gaps = 2/128 (1%)
Frame = +3
Query: 168 ANAMPPGKFADFTNVLHGEQYIEFVGDFPAPRESSQPVVTLSISWTRAPAPWPL*TVKYS 347
A + PG+ + F + + Y + PR+ + +T ++ T P+P P S
Sbjct: 1091 AGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDP-----GS 1145
Query: 348 KISNWYAEPSSTFSC*AKEVSVDPAIARTLSASETHRSEILMPSWN--NAPPKTRLSLQN 521
S W SS+ S +V++ + + + WN N P T L+ N
Sbjct: 1146 ARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSN 1205
Query: 522 VW*PQSSA 545
+ P S A
Sbjct: 1206 I--PTSGA 1211
>X64877-1|CAA46096.1| 270|Homo sapiens serum protein protein.
Length = 270
Score = 30.7 bits (66), Expect = 5.0
Identities = 16/42 (38%), Positives = 21/42 (50%)
Frame = -3
Query: 561 NVGINMQRIEVTRHSVERAWSSAVRCSTTASGFRFGAFPTPI 436
N G +Q E VER WS+ +C +T S + G P PI
Sbjct: 115 NTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGP-PPPI 155
>BC022283-1|AAH22283.1| 270|Homo sapiens complement factor
H-related 2 protein.
Length = 270
Score = 30.7 bits (66), Expect = 5.0
Identities = 16/42 (38%), Positives = 21/42 (50%)
Frame = -3
Query: 561 NVGINMQRIEVTRHSVERAWSSAVRCSTTASGFRFGAFPTPI 436
N G +Q E VER WS+ +C +T S + G P PI
Sbjct: 115 NTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGP-PPPI 155
>BC016966-1|AAH16966.1| 262|Homo sapiens ANGEL2 protein protein.
Length = 262
Score = 30.7 bits (66), Expect = 5.0
Identities = 9/20 (45%), Positives = 14/20 (70%), Gaps = 1/20 (5%)
Frame = -3
Query: 402 PWPSTKMCCWVRH-TNCLFW 346
PW + + CCW RH ++C+ W
Sbjct: 16 PWENLQRCCWNRHISSCMRW 35
>AL592449-5|CAH71920.1| 544|Homo sapiens novel protein protein.
Length = 544
Score = 30.7 bits (66), Expect = 5.0
Identities = 9/20 (45%), Positives = 14/20 (70%), Gaps = 1/20 (5%)
Frame = -3
Query: 402 PWPSTKMCCWVRH-TNCLFW 346
PW + + CCW RH ++C+ W
Sbjct: 38 PWENLQRCCWNRHISSCMRW 57
>AL139418-1|CAI21979.1| 270|Homo sapiens complement factor
H-related 2 protein.
Length = 270
Score = 30.7 bits (66), Expect = 5.0
Identities = 16/42 (38%), Positives = 21/42 (50%)
Frame = -3
Query: 561 NVGINMQRIEVTRHSVERAWSSAVRCSTTASGFRFGAFPTPI 436
N G +Q E VER WS+ +C +T S + G P PI
Sbjct: 115 NTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGP-PPPI 155
>AK125200-1|BAC86082.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ43210 fis, clone FEBRA2020582. ).
Length = 146
Score = 30.7 bits (66), Expect = 5.0
Identities = 28/80 (35%), Positives = 35/80 (43%)
Frame = -1
Query: 605 ASPWRIGFLCPLAVATLGSICRGLRSPDIL*REPGLRRCVVPRRHQDFASVXXXXXXRSC 426
ASP+R G A T RGL +P +L R GLRRC P+R ++ C
Sbjct: 40 ASPYRWG----AAQCTPEGGRRGLGTPPVL-RRRGLRRCCPPQR-----ALGLGLRRSKC 89
Query: 425 YCGVHRNLLGLARKCAAGFG 366
G R A +CAA G
Sbjct: 90 LPGAGRQGGAGAARCAAALG 109
>BX538130-1|CAD98031.1| 986|Homo sapiens hypothetical protein
protein.
Length = 986
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/41 (31%), Positives = 23/41 (56%)
Frame = +1
Query: 214 FTESSTLNSSVTSLHRGSLHNPLLRCRYPGQGLQRRGHCEQ 336
F E L + +++RG+ + RC YP + +R+ HC+Q
Sbjct: 880 FEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQ 920
>BC060862-1|AAH60862.1| 985|Homo sapiens ring finger protein 111
protein.
Length = 985
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/41 (31%), Positives = 23/41 (56%)
Frame = +1
Query: 214 FTESSTLNSSVTSLHRGSLHNPLLRCRYPGQGLQRRGHCEQ 336
F E L + +++RG+ + RC YP + +R+ HC+Q
Sbjct: 879 FEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQ 919
>BC010369-1|AAH10369.1| 137|Homo sapiens RNF111 protein protein.
Length = 137
Score = 30.3 bits (65), Expect = 6.6
Identities = 13/41 (31%), Positives = 23/41 (56%)
Frame = +1
Query: 214 FTESSTLNSSVTSLHRGSLHNPLLRCRYPGQGLQRRGHCEQ 336
F E L + +++RG+ + RC YP + +R+ HC+Q
Sbjct: 31 FEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQ 71
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,173,028
Number of Sequences: 237096
Number of extensions: 2832252
Number of successful extensions: 7799
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 7219
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7790
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7671262118
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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