Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= cesb0051
(739 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 285 9e-77
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 285 9e-77
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 285 9e-77
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 277 3e-74
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 277 3e-74
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 277 3e-74
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 277 3e-74
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 277 3e-74
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 277 3e-74
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 277 3e-74
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 275 9e-74
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 239 1e-62
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 239 1e-62
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 239 1e-62
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 239 1e-62
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 239 1e-62
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 167 5e-41
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 167 5e-41
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 167 5e-41
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 148 2e-35
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 148 2e-35
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 148 2e-35
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 148 2e-35
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 148 2e-35
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 148 2e-35
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 148 2e-35
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 148 2e-35
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 148 2e-35
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 148 2e-35
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 148 2e-35
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 142 2e-33
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 142 2e-33
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 142 2e-33
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 142 2e-33
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 141 2e-33
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 141 2e-33
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 141 2e-33
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 141 2e-33
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 141 2e-33
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 140 5e-33
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 131 3e-30
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 130 4e-30
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 129 9e-30
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 129 9e-30
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 129 9e-30
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 129 9e-30
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 129 9e-30
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 128 3e-29
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 128 3e-29
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 125 1e-28
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 125 1e-28
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 125 1e-28
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 125 1e-28
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 125 1e-28
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 125 1e-28
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 124 3e-28
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 124 3e-28
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 124 4e-28
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 123 8e-28
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 123 8e-28
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 122 1e-27
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 118 2e-26
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 118 3e-26
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 118 3e-26
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 118 3e-26
AL158217-11|CAI22163.1| 854|Homo sapiens espin protein. 116 7e-26
AL031848-3|CAI19773.1| 854|Homo sapiens espin protein. 116 7e-26
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 116 1e-25
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 116 1e-25
BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS... 116 1e-25
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 116 1e-25
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 116 1e-25
BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 2... 114 3e-25
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 114 3e-25
AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens ... 113 5e-25
AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens ... 113 6e-25
AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containi... 113 6e-25
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 113 8e-25
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 113 8e-25
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 113 8e-25
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 113 8e-25
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 113 8e-25
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 113 8e-25
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 113 8e-25
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 112 1e-24
BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein. 111 3e-24
AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens ... 111 3e-24
AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein. 111 3e-24
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 111 3e-24
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 111 3e-24
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 111 3e-24
AL031177-6|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 111 3e-24
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 111 3e-24
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 111 3e-24
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 111 3e-24
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 110 4e-24
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 110 6e-24
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 110 6e-24
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 109 1e-23
AL080091-1|CAB45706.2| 266|Homo sapiens hypothetical protein pr... 109 1e-23
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 108 2e-23
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 108 2e-23
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 108 2e-23
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 108 2e-23
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 108 2e-23
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 108 2e-23
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 108 2e-23
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 108 2e-23
BC150486-1|AAI50487.1| 627|Homo sapiens ankyrin repeat and KH d... 107 4e-23
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 107 4e-23
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 107 4e-23
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 107 4e-23
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 107 4e-23
BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH d... 107 4e-23
AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens ... 107 4e-23
AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein. 107 4e-23
BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein. 107 5e-23
BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein. 107 5e-23
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 106 7e-23
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 106 7e-23
AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens ... 106 7e-23
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 105 1e-22
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 105 1e-22
BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein. 105 1e-22
AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2 (Dro... 105 1e-22
AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2 (Dro... 105 1e-22
AL691432-2|CAM12830.1| 948|Homo sapiens mindbomb homolog 2 (Dro... 105 1e-22
AL691432-1|CAM12831.1| 999|Homo sapiens mindbomb homolog 2 (Dro... 105 1e-22
AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activatin... 105 1e-22
AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma prot... 105 1e-22
AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein. 105 1e-22
AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha prot... 105 1e-22
AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein. 105 1e-22
BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein. 105 2e-22
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 105 2e-22
AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined b... 105 2e-22
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 104 3e-22
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 104 4e-22
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 104 4e-22
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 104 4e-22
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 104 4e-22
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 104 4e-22
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 104 4e-22
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 104 4e-22
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 104 4e-22
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 103 5e-22
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 103 5e-22
AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein. 103 5e-22
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 103 7e-22
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 102 2e-21
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 102 2e-21
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 101 2e-21
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 101 2e-21
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 101 2e-21
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 101 2e-21
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 101 2e-21
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 101 2e-21
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 101 2e-21
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 101 2e-21
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 101 2e-21
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 101 2e-21
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 101 2e-21
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 101 2e-21
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 101 2e-21
AL671762-16|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 101 2e-21
AL671762-15|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 101 2e-21
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 101 2e-21
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 101 2e-21
AL662834-27|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 101 2e-21
AL662834-26|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 101 2e-21
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 101 2e-21
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 101 2e-21
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 101 2e-21
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 101 2e-21
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 101 2e-21
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 101 2e-21
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 101 2e-21
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 100 5e-21
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 100 5e-21
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 100 5e-21
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 100 1e-20
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 99 2e-20
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 99 2e-20
BC065710-1|AAH65710.1| 329|Homo sapiens ankyrin repeat and SOCS... 99 2e-20
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 99 2e-20
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 99 2e-20
AY057053-1|AAL18248.1| 329|Homo sapiens SOCS box protein ASB-5 ... 99 2e-20
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 99 2e-20
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 99 2e-20
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 99 2e-20
AK098693-1|BAC05382.1| 276|Homo sapiens protein ( Homo sapiens ... 99 2e-20
AK096441-1|BAC04791.1| 329|Homo sapiens protein ( Homo sapiens ... 99 2e-20
BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS... 98 3e-20
AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens ... 98 3e-20
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei... 98 3e-20
AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat domain-c... 98 3e-20
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 97 6e-20
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 96 1e-19
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 96 1e-19
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 96 1e-19
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 96 1e-19
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 96 1e-19
BC051904-1|AAH51904.1| 752|Homo sapiens phospholipase A2, group... 96 1e-19
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 96 1e-19
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 96 1e-19
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 96 1e-19
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 96 1e-19
AF102988-1|AAD41722.1| 752|Homo sapiens Ca2+-independent phosph... 96 1e-19
BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1, ... 96 1e-19
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 96 1e-19
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 96 1e-19
AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1, ... 96 1e-19
AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1, ... 96 1e-19
AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP ... 96 1e-19
AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein. 96 1e-19
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 95 2e-19
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 95 2e-19
BC001244-1|AAH01244.1| 252|Homo sapiens ASB9 protein protein. 95 2e-19
AB033081-1|BAA86569.2| 1232|Homo sapiens KIAA1255 protein protein. 95 2e-19
DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein. 95 3e-19
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 95 3e-19
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 95 3e-19
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 95 3e-19
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 95 3e-19
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 95 3e-19
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 95 3e-19
DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein. 94 4e-19
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 94 5e-19
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 93 7e-19
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 93 7e-19
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 93 7e-19
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 93 7e-19
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 93 7e-19
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 93 7e-19
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 93 7e-19
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 93 7e-19
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 93 7e-19
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 93 7e-19
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 93 7e-19
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 93 7e-19
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 93 7e-19
AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens ... 93 9e-19
AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6... 93 1e-18
AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6... 93 1e-18
AF403033-1|AAL57352.1| 434|Homo sapiens ankyrin repeat domain-c... 93 1e-18
AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein pr... 92 2e-18
AL031177-2|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 91 3e-18
AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein. 91 4e-18
Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein prot... 91 5e-18
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 91 5e-18
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 91 5e-18
BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lys... 90 7e-18
AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic histone-ly... 90 7e-18
AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic histone-ly... 90 7e-18
AB037360-1|BAA90300.1| 1166|Homo sapiens ANKHZN protein. 90 7e-18
EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat ... 90 9e-18
Z47748-1|CAB94757.1| 969|Homo sapiens NFKB1 protein. 88 3e-17
M58603-1|AAA36360.1| 968|Homo sapiens nuclear factor kappa-B DN... 88 3e-17
M55643-1|AAA36361.1| 969|Homo sapiens factor KBF1 protein. 88 3e-17
BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein pr... 88 3e-17
BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS... 88 3e-17
BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS... 88 3e-17
BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS... 88 3e-17
BC051765-1|AAH51765.1| 969|Homo sapiens nuclear factor of kappa... 88 3e-17
BC033210-1|AAH33210.1| 550|Homo sapiens NFKB1 protein protein. 88 3e-17
AY223820-1|AAO30127.1| 968|Homo sapiens nuclear factor of kappa... 88 3e-17
AF425642-1|AAL60519.1| 323|Homo sapiens ankyrin repeat domain-c... 88 3e-17
AF213884-1|AAF35232.1| 968|Homo sapiens nuclear factor of kappa... 88 3e-17
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 88 3e-17
AY337578-1|AAQ17469.1| 233|Homo sapiens ankyrin repeat and SOCS... 88 4e-17
BC004988-1|AAH04988.1| 669|Homo sapiens fem-1 homolog a (C. ele... 86 1e-16
AY356352-1|AAR10439.1| 669|Homo sapiens prostaglandin E recepto... 86 1e-16
AJ311359-1|CAC85342.1| 668|Homo sapiens putative sex determinin... 86 1e-16
CR456543-1|CAG30429.1| 806|Homo sapiens PLA2G6 protein. 86 1e-16
BC045621-1|AAH45621.1| 198|Homo sapiens ANKRD42 protein protein. 86 1e-16
BC036742-1|AAH36742.2| 806|Homo sapiens phospholipase A2, group... 86 1e-16
AY522921-1|AAR92478.1| 806|Homo sapiens phospholipase A2, group... 86 1e-16
AL022322-2|CAA18446.1| 806|Homo sapiens phospholipase A2, group... 86 1e-16
AF117692-1|AAD30424.1| 806|Homo sapiens calcium-independent pho... 86 1e-16
AF116267-1|AAF34728.1| 806|Homo sapiens calcium-independent pho... 86 1e-16
AF102989-1|AAD41723.1| 806|Homo sapiens Ca2+-independent phosph... 86 1e-16
AF064594-1|AAC97486.1| 806|Homo sapiens calcium-independent pho... 86 1e-16
AB075861-1|BAB85567.1| 863|Homo sapiens KIAA1981 protein protein. 85 2e-16
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 85 3e-16
AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein. 85 3e-16
AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein. 85 3e-16
AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein. 85 3e-16
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 85 3e-16
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 85 3e-16
U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma ... 84 4e-16
M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein. 84 4e-16
CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in pr... 84 4e-16
BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein. 84 4e-16
BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3 p... 84 4e-16
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 84 4e-16
AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein. 84 4e-16
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 84 4e-16
AF312028-1|AAG60045.1| 782|Homo sapiens myosin binding subunit ... 84 6e-16
AB209452-1|BAD92689.1| 736|Homo sapiens protein phosphatase 1, ... 84 6e-16
EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin prot... 83 8e-16
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 83 8e-16
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 83 8e-16
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 83 8e-16
AK093479-1|BAC04181.1| 530|Homo sapiens protein ( Homo sapiens ... 83 1e-15
AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein. 83 1e-15
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 83 1e-15
AL031177-3|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 83 1e-15
D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target... 82 2e-15
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 82 2e-15
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 82 2e-15
BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein. 82 2e-15
BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein. 82 2e-15
BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein. 82 2e-15
BC035234-1|AAH35234.1| 343|Homo sapiens ankyrin repeat domain 5... 82 2e-15
BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for IM... 82 2e-15
AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase targ... 82 2e-15
AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase targ... 82 2e-15
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 82 2e-15
DQ152234-1|AAZ77790.1| 707|Homo sapiens Shank2E protein. 82 2e-15
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 82 2e-15
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 82 2e-15
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 82 2e-15
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 82 2e-15
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 82 2e-15
BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS... 81 3e-15
AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS... 81 3e-15
AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS... 81 3e-15
AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens ... 81 3e-15
AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containi... 81 3e-15
CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein. 81 4e-15
BC100877-1|AAI00878.1| 241|Homo sapiens ASB15 protein protein. 81 4e-15
BC100876-1|AAI00877.1| 241|Homo sapiens ASB15 protein protein. 81 4e-15
BC100875-1|AAI00876.1| 241|Homo sapiens ASB15 protein protein. 81 4e-15
BC100874-1|AAI00875.1| 241|Homo sapiens ASB15 protein protein. 81 4e-15
AY462869-1|AAS58863.1| 498|Homo sapiens POTE8A protein. 81 4e-15
AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS... 81 4e-15
AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat domain-c... 81 4e-15
AF163302-1|AAD45121.1| 2161|Homo sapiens somatostatin receptor i... 81 4e-15
DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein. 81 5e-15
AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and ster... 81 5e-15
AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and ster... 81 5e-15
U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory facto... 80 7e-15
U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory facto... 80 7e-15
U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory facto... 80 7e-15
U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory facto... 80 7e-15
D13317-1|BAA02574.1| 383|Homo sapiens transcription factor E4TF... 80 7e-15
D13316-1|BAA02573.1| 347|Homo sapiens transcription factor E4TF... 80 7e-15
BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein tran... 80 7e-15
BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein tran... 80 7e-15
BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein tran... 80 7e-15
BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein tran... 80 7e-15
BC014558-1|AAH14558.1| 627|Homo sapiens fem-1 homolog b (C. ele... 80 7e-15
BC010122-1|AAH10122.1| 627|Homo sapiens fem-1 homolog b (C. ele... 80 7e-15
AF204883-1|AAF69303.1| 627|Homo sapiens FEM1 beta protein. 80 7e-15
AF178632-1|AAF05314.1| 627|Homo sapiens FEM-1-like death recept... 80 7e-15
AB007856-1|BAA23692.2| 627|Homo sapiens KIAA0396 protein. 80 7e-15
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 80 9e-15
BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in pr... 80 9e-15
BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in pr... 80 9e-15
BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein. 80 9e-15
AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein. 80 9e-15
AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein. 80 9e-15
AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein. 80 9e-15
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 80 9e-15
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 80 9e-15
Z97630-4|CAB63057.1| 300|Homo sapiens protein ( Human DNA seque... 79 1e-14
DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein. 79 1e-14
CR456471-1|CAG30357.1| 300|Homo sapiens dJ466N1.4 protein. 79 1e-14
BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding prote... 79 1e-14
BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein. 79 1e-14
BC066909-1|AAH66909.1| 300|Homo sapiens ankyrin repeat domain 5... 79 1e-14
BC017798-1|AAH17798.1| 239|Homo sapiens ankyrin repeat domain 4... 79 1e-14
BC014641-1|AAH14641.1| 300|Homo sapiens ankyrin repeat domain 5... 79 1e-14
AK000196-1|BAA91003.1| 239|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding prote... 79 1e-14
AF025354-1|AAK60412.1| 239|Homo sapiens fetal globin-inducing f... 79 1e-14
AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein. 79 1e-14
BC036020-1|AAH36020.1| 622|Homo sapiens zinc finger, DHHC-type ... 79 2e-14
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 79 2e-14
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 79 2e-14
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 79 2e-14
AK001714-1|BAA91856.1| 481|Homo sapiens protein ( Homo sapiens ... 79 2e-14
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 79 2e-14
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 79 2e-14
AB024495-1|BAC22090.1| 622|Homo sapiens huntingtin interacting ... 79 2e-14
AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein. 79 2e-14
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 78 3e-14
L10381-1|AAA18032.1| 741|Homo sapiens 2-5A-dependent RNase prot... 78 3e-14
BC115697-1|AAI15698.1| 741|Homo sapiens ribonuclease L (2',5'-o... 78 3e-14
BC114433-1|AAI14434.1| 741|Homo sapiens ribonuclease L protein. 78 3e-14
BC090934-1|AAH90934.1| 652|Homo sapiens RNASEL protein protein. 78 3e-14
BC063609-1|AAH63609.1| 423|Homo sapiens NFKBIE protein protein. 78 3e-14
BC027033-1|AAH27033.1| 448|Homo sapiens hypothetical protein MG... 78 3e-14
BC011676-1|AAH11676.2| 423|Homo sapiens NFKBIE protein protein. 78 3e-14
AL691467-2|CAH73760.1| 410|Homo sapiens novel protein protein. 78 3e-14
AL691467-1|CAH73759.1| 448|Homo sapiens novel protein protein. 78 3e-14
AL592424-25|CAI16391.1| 410|Homo sapiens novel protein protein. 78 3e-14
AL592424-24|CAI16392.1| 448|Homo sapiens novel protein protein. 78 3e-14
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 78 3e-14
AL590133-27|CAI13352.1| 410|Homo sapiens novel protein protein. 78 3e-14
AL590133-26|CAI13351.1| 448|Homo sapiens novel protein protein. 78 3e-14
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 78 3e-14
AL139392-10|CAI20103.1| 500|Homo sapiens nuclear factor of kapp... 78 3e-14
AL138776-1|CAH71322.1| 741|Homo sapiens ribonuclease L (2',5'-o... 78 3e-14
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 78 3e-14
AF261937-1|AAM27002.1| 361|Homo sapiens NFKBIE protein protein. 78 3e-14
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 78 3e-14
U91616-1|AAC51216.1| 500|Homo sapiens I kappa B epsilon protein. 78 4e-14
BC056152-1|AAH56152.1| 622|Homo sapiens zinc finger, DHHC-type ... 78 4e-14
AY462872-1|AAS58866.1| 394|Homo sapiens POTE2B protein. 78 4e-14
AB097027-1|BAC77380.1| 622|Homo sapiens putative MAPK activatin... 78 4e-14
AB097014-1|BAC77367.1| 622|Homo sapiens putative NFkB activatin... 78 4e-14
BC110907-1|AAI10908.1| 515|Homo sapiens PPP1R12B protein protein. 77 5e-14
BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2... 77 5e-14
BC034430-1|AAH34430.1| 386|Homo sapiens PPP1R12B protein protein. 77 5e-14
AL589762-3|CAH73375.1| 982|Homo sapiens protein phosphatase 1, ... 77 5e-14
AL589762-2|CAH73374.1| 386|Homo sapiens protein phosphatase 1, ... 77 5e-14
AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2... 77 5e-14
AL356953-9|CAI15935.1| 982|Homo sapiens protein phosphatase 1, ... 77 5e-14
AL356953-8|CAI15934.1| 386|Homo sapiens protein phosphatase 1, ... 77 5e-14
AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2... 77 5e-14
AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein ... 77 5e-14
AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin... 77 5e-14
AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin... 77 5e-14
AF324892-1|AAK00336.1| 982|Homo sapiens myosin phosphatase targ... 77 5e-14
AF324888-1|AAK00337.1| 982|Homo sapiens myosin phosphatase targ... 77 5e-14
AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein ... 77 5e-14
AB003062-1|BAA28376.1| 982|Homo sapiens myosin phosphatase targ... 77 5e-14
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 77 7e-14
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 77 7e-14
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 77 7e-14
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 77 7e-14
AK092230-1|BAC03833.1| 448|Homo sapiens ITOCHONDRIAL PRECURSOR.... 77 7e-14
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 77 9e-14
BX537857-1|CAD97864.1| 306|Homo sapiens hypothetical protein pr... 76 1e-13
BC050324-1|AAH50324.1| 632|Homo sapiens zinc finger, DHHC-type ... 76 1e-13
BC032799-1|AAH32799.1| 201|Homo sapiens ANKRD7 protein protein. 76 1e-13
BC030990-1|AAH30990.1| 276|Homo sapiens ZDHHC17 protein protein. 76 1e-13
AB097035-1|BAC77388.1| 622|Homo sapiens putative MAPK activatin... 76 1e-13
AB097013-1|BAC77366.1| 622|Homo sapiens putative NFkB activatin... 76 1e-13
AB023163-1|BAA76790.1| 667|Homo sapiens KIAA0946 protein protein. 76 1e-13
X61498-1|CAA43715.1| 933|Homo sapiens NF-kB subunit protein. 75 3e-13
S76638-1|AAB21124.1| 900|Homo sapiens p50-NF-kappa B homolog pr... 75 3e-13
BT009769-1|AAP88771.1| 899|Homo sapiens nuclear factor of kappa... 75 3e-13
BC002844-1|AAH02844.1| 899|Homo sapiens nuclear factor of kappa... 75 3e-13
AY865619-1|AAW56071.1| 900|Homo sapiens nuclear factor of kappa... 75 3e-13
AL121928-1|CAC08399.1| 900|Homo sapiens nuclear factor of kappa... 75 3e-13
BC113481-1|AAI13482.1| 349|Homo sapiens ankyrin repeat and SOCS... 75 4e-13
BC113479-1|AAI13480.1| 349|Homo sapiens ankyrin repeat and SOCS... 75 4e-13
BC025024-1|AAH25024.1| 318|Homo sapiens Unknown (protein for IM... 75 4e-13
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 75 4e-13
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 75 4e-13
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 75 4e-13
AK027869-1|BAB55419.1| 773|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 75 4e-13
AF156779-1|AAD41896.1| 426|Homo sapiens ASB-4 protein protein. 75 4e-13
AC003079-1|AAB83943.2| 426|Homo sapiens unknown protein. 75 4e-13
BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1, ... 74 5e-13
BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1, ... 74 5e-13
BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1, ... 74 5e-13
BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1, ... 74 5e-13
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 74 5e-13
AL357148-2|CAI16568.1| 1460|Homo sapiens ankyrin repeat domain 3... 73 8e-13
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 285 bits (700), Expect = 9e-77
Identities = 139/224 (62%), Positives = 168/224 (75%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+RGET +H+AARA +++R LLRNGA V+A+ARE QTPLHIASRLG +I LLLQH A
Sbjct: 462 IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 521
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T + Y PLHI+A++ DVA+ L+E A + TKKGFT LH+AAKYG+L VA L
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKL 581
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL AA D AGKNG+TPLH+AA YD Q VA LLEKGA A AKNG+TPLHIAA+KNQ
Sbjct: 582 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ 641
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M+ A+TLL YGA TN +K G TPLHLA+Q+GHT+M LLL+ G
Sbjct: 642 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKG 685
Score = 187 bits (456), Expect = 3e-47
Identities = 95/221 (42%), Positives = 137/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+A+R T+I+++LL++ A +A TPLHI++R G VD+A +LL+ GA
Sbjct: 498 QTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS 557
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK + DVA L++ A + K G T LH+AA Y N KVA LLL
Sbjct: 558 LATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLE 617
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P KNG TPLHIAA+ +Q +A+TLL GA+ V K G TPLH+A+++ +
Sbjct: 618 KGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDM 677
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA + +K+G T LHLAAQ+ + +L + G
Sbjct: 678 VTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 718
Score = 185 bits (450), Expect = 2e-46
Identities = 94/225 (41%), Positives = 139/225 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ D+ ++LL+ AA ++ + TPLH+A+ N +A+LLL+ G
Sbjct: 560 TKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 619
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ +A+ L+ + A TK+G T LHLA++ G+ +
Sbjct: 620 ASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVT 679
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+G+T LH+AAQ D+ VA L + GAD A K G+TPL +A
Sbjct: 680 LLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYG 739
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+ GA NA++K G+TPLH AAQQGHT + +LL+ G
Sbjct: 740 NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784
Score = 182 bits (444), Expect = 9e-46
Identities = 94/228 (41%), Positives = 140/228 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ +LL+NGA+ + +T LH+A+R G V++ LL++G
Sbjct: 428 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A + PLHIA++ ++ L++H A A T G+T LH++A+ G + VA+
Sbjct: 488 ALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVAS 547
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL GAA A K G TPLH+AA+Y VA LL++ A A + KNG TPLH+AA +
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 607
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ A LLE GA +A +K G+TPLH+AA++ ++ + LL G T
Sbjct: 608 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAET 655
Score = 180 bits (438), Expect = 5e-45
Identities = 93/225 (41%), Positives = 132/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA + ++ +LL GAAV+ AR TPLH+AS+ GN ++ LLL G
Sbjct: 230 TESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 289
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A T D PLH AA+ + V L+E APL A TK G + LH+AA+ +++
Sbjct: 290 GQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVK 349
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL H A D + +T LH+AA V LL+K A+ A A NG TPLHIA +KN
Sbjct: 350 HLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKN 409
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+++ L++YGA A +++G TP+H+AA GH + LLL+ G
Sbjct: 410 RIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNG 454
Score = 175 bits (425), Expect = 2e-43
Identities = 89/225 (39%), Positives = 136/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H++AR D+ +LL GAA ++ TPLH+A++ G++D+A LLLQ
Sbjct: 527 TTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRR 586
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + PLH+AA N VA L+E A AT K G+T LH+AAK +++A+
Sbjct: 587 AAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIAS 646
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + K G+TPLH+A+Q + T LL+KGA+ K+G T LH+AA+++
Sbjct: 647 TLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQED 706
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ A L ++GA +A +K G+TPL +A G+ +M LL+ G
Sbjct: 707 KVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQG 751
Score = 167 bits (405), Expect = 5e-41
Identities = 84/224 (37%), Positives = 132/224 (58%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +L++ GA+++A TP+H+A+ +G+++I +LLLQ+GA
Sbjct: 396 LNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 455
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L+ + A + A ++ T LH+A++ G ++ L
Sbjct: 456 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQL 515
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL H A PD A NG TPLHI+A+ Q VA+ LLE GA K G TPLH+AA+
Sbjct: 516 LLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGS 575
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ A LL+ A ++ K G TPLH+AA + ++ LLLE G
Sbjct: 576 LDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 619
Score = 165 bits (401), Expect = 1e-40
Identities = 83/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A A+A TPLHIA + + + LL+++GA ++A
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQA 426
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT P+H+AA + ++ L+++ A T +G TALH+AA+ G ++V LL +
Sbjct: 427 ITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN 486
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA D + TPLHIA++ + + LL+ A A NG+TPLHI+AR+ Q++ A
Sbjct: 487 GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVA 546
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LLE GA + +K GFTPLH+AA+ G ++ LLL+
Sbjct: 547 SVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ 584
Score = 162 bits (394), Expect = 1e-39
Identities = 83/222 (37%), Positives = 132/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A++ +T+++++LL G ++AK R+ TPLH A+R G+ + LLL+ GA +
Sbjct: 266 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 325
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + +PLH+AA+ + + L++H AP+ T TALH+AA G+ +V LLL
Sbjct: 326 LARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLL 385
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A P+ NG TPLHIA + ++ V L++ GA +A+ ++G TP+H+AA +
Sbjct: 386 DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN 445
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA + + G T LH+AA+ G E+ LL G
Sbjct: 446 IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Score = 161 bits (390), Expect = 3e-39
Identities = 84/231 (36%), Positives = 134/231 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H + ++ LL++ A V+ + T LH+A+ G+ + LLL
Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKR 388
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L+++ A + A T+ G T +H+AA G+L +
Sbjct: 389 ANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL 448
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL +GA+PD G T LH+AA+ Q V LL GA A A+ TPLHIA+R
Sbjct: 449 LLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLG 508
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
+ E LL++ A +A + G+TPLH++A++G ++ ++LLE G A
Sbjct: 509 KTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLA 559
Score = 160 bits (389), Expect = 4e-39
Identities = 83/220 (37%), Positives = 126/220 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AAR+ H ++ +LL GA + A+ + +PLH+A++ +V+ LLQH A V
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 358
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ V L++ A A GFT LH+A K +KV LL+
Sbjct: 359 DDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV 418
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA+ ++G+TP+H+AA + LL+ GA G T LH+AAR Q+E
Sbjct: 419 KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVE 478
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL GAL +A ++ TPLH+A++ G TE+ LLL+
Sbjct: 479 VVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 518
Score = 156 bits (379), Expect = 7e-38
Identities = 80/211 (37%), Positives = 123/211 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ + IA LL +GA+
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAET 655
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+A+++ + D+ L++ A + +TK G T+LHLAA+ + VA++L
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILT 715
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D K G TPL +A Y + LL++GA+ A KNG+TPLH AA++
Sbjct: 716 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 775
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL++GA NA + G T L +A + G+
Sbjct: 776 IINVLLQHGAKPNATTANGNTALAIAKRLGY 806
Score = 154 bits (373), Expect = 4e-37
Identities = 83/233 (35%), Positives = 135/233 (57%), Gaps = 8/233 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L++ GA + A+++ TPL++A++ ++D+ LL++G
Sbjct: 94 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENG 153
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q ++ A L+E++ K ALH+AA+ + K A
Sbjct: 154 ANQSTATEDGFTPLAVALQQGHNQAVAILLEND----TKGKVRLPALHIAARKDDTKSAA 209
Query: 361 LLLAHGAAPDQAGK--------NGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
LLL + D K +G TPLHIAA Y VAT LL +GA A+NG TP
Sbjct: 210 LLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITP 269
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LH+A+++ LL+ G +A+++ G TPLH AA+ GH ++ LLLE G
Sbjct: 270 LHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 322
Score = 139 bits (337), Expect = 8e-33
Identities = 79/230 (34%), Positives = 132/230 (57%), Gaps = 8/230 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLAA+ H +++ LL G++V++ ++ T LHIAS G ++ +L++ GA++
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANI 123
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ DV L+E+ A + T+ GFT L +A + G+ + +LL
Sbjct: 124 NAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--------NGHTPLHI 525
+ D GK + LHIAA+ D A LL+ +A +K +G TPLHI
Sbjct: 184 EN----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHI 239
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
AA + A LL GA + ++ G TPLH+A+++G+T M LLL+ G
Sbjct: 240 AAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 289
Score = 138 bits (334), Expect = 2e-32
Identities = 75/185 (40%), Positives = 100/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N I LL GA ++ TPLH+AS+ G+ D+ LLL GA++
Sbjct: 629 GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANI 688
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T LH+AA++ +VA L +H A A TK G+T L +A YGN+K+ N LL
Sbjct: 689 HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLL 748
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + KNG TPLH AAQ + LL+ GA A NG+T L IA R +
Sbjct: 749 KQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYIS 808
Query: 550 TAATL 564
TL
Sbjct: 809 VVDTL 813
Score = 138 bits (333), Expect = 3e-32
Identities = 84/230 (36%), Positives = 123/230 (53%), Gaps = 8/230 (3%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRN--GAAVEAKARERQT------PLHIASRLGNVDIAVLLLQH 177
+H+AAR + T +LL+N A V++K +T PLHIA+ GNV++A LLL
Sbjct: 196 LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
GA V + PLH+A+K+ N ++ L++ + A T+ G T LH AA+ G+ +V
Sbjct: 256 GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVV 315
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LLL GA KNG++PLH+AAQ D LL+ A V + T LH+AA
Sbjct: 316 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 375
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA + GFTPLH+A ++ ++ LL++ G Q
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Score = 114 bits (275), Expect = 3e-25
Identities = 76/228 (33%), Positives = 116/228 (50%), Gaps = 8/228 (3%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA + D + L+ G + + LH+A++ G+V + LL G+ V + T
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L++ A + A ++ GFT L++AA+ ++ V LL +GA
Sbjct: 98 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 157
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL- 567
A ++G TPL +A Q LLE D K K LHIAARK+ ++AA LL
Sbjct: 158 TATEDGFTPLAVALQQGHNQAVAILLEN--DTK--GKVRLPALHIAARKDDTKSAALLLQ 213
Query: 568 -EYGA------LTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
++ A + N +++GFTPLH+AA G+ + LLL G F
Sbjct: 214 NDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 261
Score = 114 bits (274), Expect = 4e-25
Identities = 60/155 (38%), Positives = 89/155 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+HLA++ HTD++ +LL GA + + T LH+A++ V++A +L +HG
Sbjct: 659 TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 718
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A T Y PL +A N + L++ A + A TK G+T LH AA+ G+ + N
Sbjct: 719 ADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIIN 778
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
+LL HGA P+ NG T L IA + +V TL
Sbjct: 779 VLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 50/100 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + ++ LL+ GA V AK + TPLH A++ G+ I +LLQHG
Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
A A TA+ L IA + V L +T TT
Sbjct: 785 AKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTT 824
Score = 31.9 bits (69), Expect = 2.5
Identities = 18/56 (32%), Positives = 26/56 (46%)
Frame = +1
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
AAR ++ L+ G N ++ G LHLAA++GH + LL G A
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 93
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 285 bits (700), Expect = 9e-77
Identities = 139/224 (62%), Positives = 168/224 (75%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+RGET +H+AARA +++R LLRNGA V+A+ARE QTPLHIASRLG +I LLLQH A
Sbjct: 462 IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 521
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T + Y PLHI+A++ DVA+ L+E A + TKKGFT LH+AAKYG+L VA L
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKL 581
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL AA D AGKNG+TPLH+AA YD Q VA LLEKGA A AKNG+TPLHIAA+KNQ
Sbjct: 582 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ 641
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M+ A+TLL YGA TN +K G TPLHLA+Q+GHT+M LLL+ G
Sbjct: 642 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKG 685
Score = 187 bits (456), Expect = 3e-47
Identities = 95/221 (42%), Positives = 137/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+A+R T+I+++LL++ A +A TPLHI++R G VD+A +LL+ GA
Sbjct: 498 QTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS 557
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK + DVA L++ A + K G T LH+AA Y N KVA LLL
Sbjct: 558 LATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLE 617
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P KNG TPLHIAA+ +Q +A+TLL GA+ V K G TPLH+A+++ +
Sbjct: 618 KGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDM 677
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA + +K+G T LHLAAQ+ + +L + G
Sbjct: 678 VTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 718
Score = 185 bits (450), Expect = 2e-46
Identities = 94/225 (41%), Positives = 139/225 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ D+ ++LL+ AA ++ + TPLH+A+ N +A+LLL+ G
Sbjct: 560 TKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 619
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ +A+ L+ + A TK+G T LHLA++ G+ +
Sbjct: 620 ASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVT 679
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+G+T LH+AAQ D+ VA L + GAD A K G+TPL +A
Sbjct: 680 LLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYG 739
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+ GA NA++K G+TPLH AAQQGHT + +LL+ G
Sbjct: 740 NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784
Score = 182 bits (444), Expect = 9e-46
Identities = 94/228 (41%), Positives = 140/228 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ +LL+NGA+ + +T LH+A+R G V++ LL++G
Sbjct: 428 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A + PLHIA++ ++ L++H A A T G+T LH++A+ G + VA+
Sbjct: 488 ALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVAS 547
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL GAA A K G TPLH+AA+Y VA LL++ A A + KNG TPLH+AA +
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 607
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ A LLE GA +A +K G+TPLH+AA++ ++ + LL G T
Sbjct: 608 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAET 655
Score = 180 bits (438), Expect = 5e-45
Identities = 93/225 (41%), Positives = 132/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA + ++ +LL GAAV+ AR TPLH+AS+ GN ++ LLL G
Sbjct: 230 TESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 289
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A T D PLH AA+ + V L+E APL A TK G + LH+AA+ +++
Sbjct: 290 GQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVK 349
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL H A D + +T LH+AA V LL+K A+ A A NG TPLHIA +KN
Sbjct: 350 HLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKN 409
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+++ L++YGA A +++G TP+H+AA GH + LLL+ G
Sbjct: 410 RIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNG 454
Score = 175 bits (425), Expect = 2e-43
Identities = 89/225 (39%), Positives = 136/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H++AR D+ +LL GAA ++ TPLH+A++ G++D+A LLLQ
Sbjct: 527 TTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRR 586
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + PLH+AA N VA L+E A AT K G+T LH+AAK +++A+
Sbjct: 587 AAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIAS 646
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + K G+TPLH+A+Q + T LL+KGA+ K+G T LH+AA+++
Sbjct: 647 TLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQED 706
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ A L ++GA +A +K G+TPL +A G+ +M LL+ G
Sbjct: 707 KVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQG 751
Score = 167 bits (405), Expect = 5e-41
Identities = 84/224 (37%), Positives = 132/224 (58%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +L++ GA+++A TP+H+A+ +G+++I +LLLQ+GA
Sbjct: 396 LNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 455
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L+ + A + A ++ T LH+A++ G ++ L
Sbjct: 456 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQL 515
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL H A PD A NG TPLHI+A+ Q VA+ LLE GA K G TPLH+AA+
Sbjct: 516 LLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGS 575
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ A LL+ A ++ K G TPLH+AA + ++ LLLE G
Sbjct: 576 LDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 619
Score = 165 bits (401), Expect = 1e-40
Identities = 83/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A A+A TPLHIA + + + LL+++GA ++A
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQA 426
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT P+H+AA + ++ L+++ A T +G TALH+AA+ G ++V LL +
Sbjct: 427 ITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN 486
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA D + TPLHIA++ + + LL+ A A NG+TPLHI+AR+ Q++ A
Sbjct: 487 GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVA 546
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LLE GA + +K GFTPLH+AA+ G ++ LLL+
Sbjct: 547 SVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ 584
Score = 162 bits (394), Expect = 1e-39
Identities = 83/222 (37%), Positives = 132/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A++ +T+++++LL G ++AK R+ TPLH A+R G+ + LLL+ GA +
Sbjct: 266 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 325
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + +PLH+AA+ + + L++H AP+ T TALH+AA G+ +V LLL
Sbjct: 326 LARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLL 385
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A P+ NG TPLHIA + ++ V L++ GA +A+ ++G TP+H+AA +
Sbjct: 386 DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN 445
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA + + G T LH+AA+ G E+ LL G
Sbjct: 446 IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Score = 161 bits (390), Expect = 3e-39
Identities = 84/231 (36%), Positives = 134/231 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H + ++ LL++ A V+ + T LH+A+ G+ + LLL
Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKR 388
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L+++ A + A T+ G T +H+AA G+L +
Sbjct: 389 ANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL 448
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL +GA+PD G T LH+AA+ Q V LL GA A A+ TPLHIA+R
Sbjct: 449 LLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLG 508
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
+ E LL++ A +A + G+TPLH++A++G ++ ++LLE G A
Sbjct: 509 KTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLA 559
Score = 160 bits (389), Expect = 4e-39
Identities = 83/220 (37%), Positives = 126/220 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AAR+ H ++ +LL GA + A+ + +PLH+A++ +V+ LLQH A V
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 358
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ V L++ A A GFT LH+A K +KV LL+
Sbjct: 359 DDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV 418
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA+ ++G+TP+H+AA + LL+ GA G T LH+AAR Q+E
Sbjct: 419 KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVE 478
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL GAL +A ++ TPLH+A++ G TE+ LLL+
Sbjct: 479 VVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 518
Score = 156 bits (379), Expect = 7e-38
Identities = 80/211 (37%), Positives = 123/211 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ + IA LL +GA+
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAET 655
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+A+++ + D+ L++ A + +TK G T+LHLAA+ + VA++L
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILT 715
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D K G TPL +A Y + LL++GA+ A KNG+TPLH AA++
Sbjct: 716 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 775
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL++GA NA + G T L +A + G+
Sbjct: 776 IINVLLQHGAKPNATTANGNTALAIAKRLGY 806
Score = 154 bits (373), Expect = 4e-37
Identities = 83/233 (35%), Positives = 135/233 (57%), Gaps = 8/233 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L++ GA + A+++ TPL++A++ ++D+ LL++G
Sbjct: 94 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENG 153
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q ++ A L+E++ K ALH+AA+ + K A
Sbjct: 154 ANQSTATEDGFTPLAVALQQGHNQAVAILLEND----TKGKVRLPALHIAARKDDTKSAA 209
Query: 361 LLLAHGAAPDQAGK--------NGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
LLL + D K +G TPLHIAA Y VAT LL +GA A+NG TP
Sbjct: 210 LLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITP 269
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LH+A+++ LL+ G +A+++ G TPLH AA+ GH ++ LLLE G
Sbjct: 270 LHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 322
Score = 139 bits (337), Expect = 8e-33
Identities = 79/230 (34%), Positives = 132/230 (57%), Gaps = 8/230 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLAA+ H +++ LL G++V++ ++ T LHIAS G ++ +L++ GA++
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANI 123
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ DV L+E+ A + T+ GFT L +A + G+ + +LL
Sbjct: 124 NAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--------NGHTPLHI 525
+ D GK + LHIAA+ D A LL+ +A +K +G TPLHI
Sbjct: 184 EN----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHI 239
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
AA + A LL GA + ++ G TPLH+A+++G+T M LLL+ G
Sbjct: 240 AAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 289
Score = 138 bits (334), Expect = 2e-32
Identities = 75/185 (40%), Positives = 100/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N I LL GA ++ TPLH+AS+ G+ D+ LLL GA++
Sbjct: 629 GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANI 688
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T LH+AA++ +VA L +H A A TK G+T L +A YGN+K+ N LL
Sbjct: 689 HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLL 748
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + KNG TPLH AAQ + LL+ GA A NG+T L IA R +
Sbjct: 749 KQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYIS 808
Query: 550 TAATL 564
TL
Sbjct: 809 VVDTL 813
Score = 138 bits (333), Expect = 3e-32
Identities = 84/230 (36%), Positives = 123/230 (53%), Gaps = 8/230 (3%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRN--GAAVEAKARERQT------PLHIASRLGNVDIAVLLLQH 177
+H+AAR + T +LL+N A V++K +T PLHIA+ GNV++A LLL
Sbjct: 196 LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
GA V + PLH+A+K+ N ++ L++ + A T+ G T LH AA+ G+ +V
Sbjct: 256 GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVV 315
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LLL GA KNG++PLH+AAQ D LL+ A V + T LH+AA
Sbjct: 316 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 375
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA + GFTPLH+A ++ ++ LL++ G Q
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Score = 114 bits (275), Expect = 3e-25
Identities = 76/228 (33%), Positives = 116/228 (50%), Gaps = 8/228 (3%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA + D + L+ G + + LH+A++ G+V + LL G+ V + T
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L++ A + A ++ GFT L++AA+ ++ V LL +GA
Sbjct: 98 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 157
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL- 567
A ++G TPL +A Q LLE D K K LHIAARK+ ++AA LL
Sbjct: 158 TATEDGFTPLAVALQQGHNQAVAILLEN--DTK--GKVRLPALHIAARKDDTKSAALLLQ 213
Query: 568 -EYGA------LTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
++ A + N +++GFTPLH+AA G+ + LLL G F
Sbjct: 214 NDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 261
Score = 114 bits (274), Expect = 4e-25
Identities = 60/155 (38%), Positives = 89/155 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+HLA++ HTD++ +LL GA + + T LH+A++ V++A +L +HG
Sbjct: 659 TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 718
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A T Y PL +A N + L++ A + A TK G+T LH AA+ G+ + N
Sbjct: 719 ADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIIN 778
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
+LL HGA P+ NG T L IA + +V TL
Sbjct: 779 VLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 50/100 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + ++ LL+ GA V AK + TPLH A++ G+ I +LLQHG
Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
A A TA+ L IA + V L +T TT
Sbjct: 785 AKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTT 824
Score = 31.9 bits (69), Expect = 2.5
Identities = 18/56 (32%), Positives = 26/56 (46%)
Frame = +1
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
AAR ++ L+ G N ++ G LHLAA++GH + LL G A
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 93
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 285 bits (700), Expect = 9e-77
Identities = 139/224 (62%), Positives = 168/224 (75%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+RGET +H+AARA +++R LLRNGA V+A+ARE QTPLHIASRLG +I LLLQH A
Sbjct: 441 IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 500
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T + Y PLHI+A++ DVA+ L+E A + TKKGFT LH+AAKYG+L VA L
Sbjct: 501 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKL 560
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL AA D AGKNG+TPLH+AA YD Q VA LLEKGA A AKNG+TPLHIAA+KNQ
Sbjct: 561 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ 620
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M+ A+TLL YGA TN +K G TPLHLA+Q+GHT+M LLL+ G
Sbjct: 621 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKG 664
Score = 187 bits (456), Expect = 3e-47
Identities = 95/221 (42%), Positives = 137/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+A+R T+I+++LL++ A +A TPLHI++R G VD+A +LL+ GA
Sbjct: 477 QTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS 536
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK + DVA L++ A + K G T LH+AA Y N KVA LLL
Sbjct: 537 LATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLE 596
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P KNG TPLHIAA+ +Q +A+TLL GA+ V K G TPLH+A+++ +
Sbjct: 597 KGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDM 656
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA + +K+G T LHLAAQ+ + +L + G
Sbjct: 657 VTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 697
Score = 185 bits (450), Expect = 2e-46
Identities = 94/225 (41%), Positives = 139/225 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ D+ ++LL+ AA ++ + TPLH+A+ N +A+LLL+ G
Sbjct: 539 TKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 598
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ +A+ L+ + A TK+G T LHLA++ G+ +
Sbjct: 599 ASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVT 658
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+G+T LH+AAQ D+ VA L + GAD A K G+TPL +A
Sbjct: 659 LLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYG 718
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+ GA NA++K G+TPLH AAQQGHT + +LL+ G
Sbjct: 719 NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 763
Score = 182 bits (444), Expect = 9e-46
Identities = 94/228 (41%), Positives = 140/228 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ +LL+NGA+ + +T LH+A+R G V++ LL++G
Sbjct: 407 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 466
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A + PLHIA++ ++ L++H A A T G+T LH++A+ G + VA+
Sbjct: 467 ALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVAS 526
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL GAA A K G TPLH+AA+Y VA LL++ A A + KNG TPLH+AA +
Sbjct: 527 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 586
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ A LLE GA +A +K G+TPLH+AA++ ++ + LL G T
Sbjct: 587 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAET 634
Score = 180 bits (438), Expect = 5e-45
Identities = 93/225 (41%), Positives = 132/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA + ++ +LL GAAV+ AR TPLH+AS+ GN ++ LLL G
Sbjct: 209 TESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 268
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A T D PLH AA+ + V L+E APL A TK G + LH+AA+ +++
Sbjct: 269 GQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVK 328
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL H A D + +T LH+AA V LL+K A+ A A NG TPLHIA +KN
Sbjct: 329 HLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKN 388
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+++ L++YGA A +++G TP+H+AA GH + LLL+ G
Sbjct: 389 RIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNG 433
Score = 175 bits (425), Expect = 2e-43
Identities = 89/225 (39%), Positives = 136/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H++AR D+ +LL GAA ++ TPLH+A++ G++D+A LLLQ
Sbjct: 506 TTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRR 565
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + PLH+AA N VA L+E A AT K G+T LH+AAK +++A+
Sbjct: 566 AAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIAS 625
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + K G+TPLH+A+Q + T LL+KGA+ K+G T LH+AA+++
Sbjct: 626 TLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQED 685
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ A L ++GA +A +K G+TPL +A G+ +M LL+ G
Sbjct: 686 KVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQG 730
Score = 167 bits (405), Expect = 5e-41
Identities = 84/224 (37%), Positives = 132/224 (58%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +L++ GA+++A TP+H+A+ +G+++I +LLLQ+GA
Sbjct: 375 LNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 434
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L+ + A + A ++ T LH+A++ G ++ L
Sbjct: 435 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQL 494
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL H A PD A NG TPLHI+A+ Q VA+ LLE GA K G TPLH+AA+
Sbjct: 495 LLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGS 554
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ A LL+ A ++ K G TPLH+AA + ++ LLLE G
Sbjct: 555 LDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 598
Score = 165 bits (401), Expect = 1e-40
Identities = 83/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A A+A TPLHIA + + + LL+++GA ++A
Sbjct: 346 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQA 405
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT P+H+AA + ++ L+++ A T +G TALH+AA+ G ++V LL +
Sbjct: 406 ITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN 465
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA D + TPLHIA++ + + LL+ A A NG+TPLHI+AR+ Q++ A
Sbjct: 466 GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVA 525
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LLE GA + +K GFTPLH+AA+ G ++ LLL+
Sbjct: 526 SVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ 563
Score = 162 bits (394), Expect = 1e-39
Identities = 83/222 (37%), Positives = 132/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A++ +T+++++LL G ++AK R+ TPLH A+R G+ + LLL+ GA +
Sbjct: 245 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 304
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + +PLH+AA+ + + L++H AP+ T TALH+AA G+ +V LLL
Sbjct: 305 LARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLL 364
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A P+ NG TPLHIA + ++ V L++ GA +A+ ++G TP+H+AA +
Sbjct: 365 DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN 424
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA + + G T LH+AA+ G E+ LL G
Sbjct: 425 IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 466
Score = 161 bits (390), Expect = 3e-39
Identities = 84/231 (36%), Positives = 134/231 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H + ++ LL++ A V+ + T LH+A+ G+ + LLL
Sbjct: 308 TKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKR 367
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L+++ A + A T+ G T +H+AA G+L +
Sbjct: 368 ANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL 427
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL +GA+PD G T LH+AA+ Q V LL GA A A+ TPLHIA+R
Sbjct: 428 LLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLG 487
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
+ E LL++ A +A + G+TPLH++A++G ++ ++LLE G A
Sbjct: 488 KTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLA 538
Score = 160 bits (389), Expect = 4e-39
Identities = 83/220 (37%), Positives = 126/220 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AAR+ H ++ +LL GA + A+ + +PLH+A++ +V+ LLQH A V
Sbjct: 278 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 337
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ V L++ A A GFT LH+A K +KV LL+
Sbjct: 338 DDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV 397
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA+ ++G+TP+H+AA + LL+ GA G T LH+AAR Q+E
Sbjct: 398 KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVE 457
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL GAL +A ++ TPLH+A++ G TE+ LLL+
Sbjct: 458 VVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 497
Score = 156 bits (379), Expect = 7e-38
Identities = 80/211 (37%), Positives = 123/211 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ + IA LL +GA+
Sbjct: 575 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAET 634
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+A+++ + D+ L++ A + +TK G T+LHLAA+ + VA++L
Sbjct: 635 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILT 694
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D K G TPL +A Y + LL++GA+ A KNG+TPLH AA++
Sbjct: 695 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 754
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL++GA NA + G T L +A + G+
Sbjct: 755 IINVLLQHGAKPNATTANGNTALAIAKRLGY 785
Score = 153 bits (372), Expect = 5e-37
Identities = 83/233 (35%), Positives = 135/233 (57%), Gaps = 8/233 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L++ GA + A+++ TPL++A++ ++D+ LL++G
Sbjct: 73 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENG 132
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q ++ A L+E++ K ALH+AA+ + K A
Sbjct: 133 ANQSTATEDGFTPLAVALQQGHNQAVAILLEND----TKGKVRLPALHIAARKDDTKSAA 188
Query: 361 LLLAHGAAPDQAGK--------NGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
LLL + D K +G TPLHIAA Y VAT LL +GA A+NG TP
Sbjct: 189 LLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITP 248
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LH+A+++ LL+ G +A+++ G TPLH AA+ GH ++ LLLE G
Sbjct: 249 LHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 301
Score = 139 bits (336), Expect = 1e-32
Identities = 79/230 (34%), Positives = 132/230 (57%), Gaps = 8/230 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLAA+ H +++ LL G++V++ ++ T LHIAS G ++ +L++ GA++
Sbjct: 43 GLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANI 102
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ DV L+E+ A + T+ GFT L +A + G+ + +LL
Sbjct: 103 NAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 162
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--------NGHTPLHI 525
+ D GK + LHIAA+ D A LL+ +A +K +G TPLHI
Sbjct: 163 EN----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHI 218
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
AA + A LL GA + ++ G TPLH+A+++G+T M LLL+ G
Sbjct: 219 AAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 268
Score = 138 bits (334), Expect = 2e-32
Identities = 75/185 (40%), Positives = 100/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N I LL GA ++ TPLH+AS+ G+ D+ LLL GA++
Sbjct: 608 GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANI 667
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T LH+AA++ +VA L +H A A TK G+T L +A YGN+K+ N LL
Sbjct: 668 HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLL 727
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + KNG TPLH AAQ + LL+ GA A NG+T L IA R +
Sbjct: 728 KQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYIS 787
Query: 550 TAATL 564
TL
Sbjct: 788 VVDTL 792
Score = 137 bits (332), Expect = 3e-32
Identities = 83/230 (36%), Positives = 123/230 (53%), Gaps = 8/230 (3%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRN--GAAVEAKARERQT------PLHIASRLGNVDIAVLLLQH 177
+H+AAR + T +LL+N A +++K +T PLHIA+ GNV++A LLL
Sbjct: 175 LHIAARKDDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 234
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
GA V + PLH+A+K+ N ++ L++ + A T+ G T LH AA+ G+ +V
Sbjct: 235 GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVV 294
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LLL GA KNG++PLH+AAQ D LL+ A V + T LH+AA
Sbjct: 295 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 354
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA + GFTPLH+A ++ ++ LL++ G Q
Sbjct: 355 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 404
Score = 114 bits (275), Expect = 3e-25
Identities = 76/228 (33%), Positives = 116/228 (50%), Gaps = 8/228 (3%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA + D + L+ G + + LH+A++ G+V + LL G+ V + T
Sbjct: 17 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 76
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L++ A + A ++ GFT L++AA+ ++ V LL +GA
Sbjct: 77 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 136
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL- 567
A ++G TPL +A Q LLE D K K LHIAARK+ ++AA LL
Sbjct: 137 TATEDGFTPLAVALQQGHNQAVAILLEN--DTK--GKVRLPALHIAARKDDTKSAALLLQ 192
Query: 568 -EYGA------LTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
++ A + N +++GFTPLH+AA G+ + LLL G F
Sbjct: 193 NDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 240
Score = 114 bits (274), Expect = 4e-25
Identities = 60/155 (38%), Positives = 89/155 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+HLA++ HTD++ +LL GA + + T LH+A++ V++A +L +HG
Sbjct: 638 TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 697
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A T Y PL +A N + L++ A + A TK G+T LH AA+ G+ + N
Sbjct: 698 ADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIIN 757
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
+LL HGA P+ NG T L IA + +V TL
Sbjct: 758 VLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 792
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 50/100 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + ++ LL+ GA V AK + TPLH A++ G+ I +LLQHG
Sbjct: 704 TKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 763
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
A A TA+ L IA + V L +T TT
Sbjct: 764 AKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTT 803
Score = 31.9 bits (69), Expect = 2.5
Identities = 18/56 (32%), Positives = 26/56 (46%)
Frame = +1
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
AAR ++ L+ G N ++ G LHLAA++GH + LL G A
Sbjct: 17 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 72
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 85 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 144
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 145 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 204
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 205 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 264
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 265 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 305
Score = 197 bits (480), Expect = 4e-50
Identities = 99/221 (44%), Positives = 138/221 (62%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 121 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 180
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 181 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 240
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 241 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 300
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A N +K+G TPLHLAAQ+ + +L+ G
Sbjct: 301 VSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 341
Score = 191 bits (466), Expect = 2e-48
Identities = 91/223 (40%), Positives = 141/223 (63%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 183 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 242
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 243 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 302
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A + + K+G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 303 LLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 362
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 363 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 405
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 51 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 110
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 111 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 170
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 171 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 230
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 231 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 275
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 19 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 78
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 79 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 138
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 139 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 198
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 199 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 242
Score = 164 bits (398), Expect = 3e-40
Identities = 81/223 (36%), Positives = 129/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 150 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 209
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 210 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 269
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ K+G TPLH+AA+++
Sbjct: 270 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQED 329
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 330 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 372
Score = 158 bits (383), Expect = 2e-38
Identities = 79/201 (39%), Positives = 120/201 (59%)
Frame = +1
Query: 67 LLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHN 246
LL A AKA TPLHIA + + + LLL+HGA ++A+T P+H+AA +
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 66
Query: 247 HDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHI 426
++ + L+ H A T +G TALH+AA+ G +V L+ GA + K+ TPLHI
Sbjct: 67 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 126
Query: 427 AAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAG 606
+A+ + + LL++GA A +G+TPLH++AR+ + AA LL++GA + +K G
Sbjct: 127 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG 186
Query: 607 FTPLHLAAQQGHTEMCALLLE 669
FTPLH+AA+ G E+ LLL+
Sbjct: 187 FTPLHVAAKYGKLEVANLLLQ 207
Score = 147 bits (356), Expect = 4e-35
Identities = 78/211 (36%), Positives = 117/211 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 219 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 278
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA + + K G T LHLAA+ + VA +L+
Sbjct: 279 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLV 338
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 339 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 398
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 399 IINVLLQNNASPNELTVNGNTALGIARRLGY 429
Score = 137 bits (332), Expect = 3e-32
Identities = 67/170 (39%), Positives = 104/170 (61%)
Frame = +1
Query: 166 LLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
LL A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G+
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 66
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+ + + L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI
Sbjct: 67 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 126
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+AR + + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 127 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 176
Score = 137 bits (331), Expect = 4e-32
Identities = 72/185 (38%), Positives = 99/185 (53%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 252 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 311
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 312 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 371
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 372 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 431
Query: 550 TAATL 564
TL
Sbjct: 432 VVDTL 436
Score = 110 bits (265), Expect = 4e-24
Identities = 69/211 (32%), Positives = 107/211 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G VHLAA+ H D++ +LL A V + TPLH+A++ V++A +L+ G
Sbjct: 282 TRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 341
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A T Y PLH+ N + L++H+A + A TK G+T LH AA+ G+ + N
Sbjct: 342 AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN 401
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL + A+P++ NG T L IA + +V TL K + + T H + N
Sbjct: 402 VLLQNNASPNELTVNGNTALGIARRLGYISVVDTL--KIVTEETMTTTTVTEKH---KMN 456
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
ET +L+ ++ G T +L Q
Sbjct: 457 VPETMNEVLDMSDDEGEDAMTGDTDKYLGPQ 487
Score = 35.9 bits (79), Expect = 0.15
Identities = 18/48 (37%), Positives = 27/48 (56%)
Frame = +1
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
M LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 1 MNLRCDLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 48
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 643
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Score = 197 bits (480), Expect = 4e-50
Identities = 99/221 (44%), Positives = 138/221 (62%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 560 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 619
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 620 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 679
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A N +K+G TPLHLAAQ+ + +L+ G
Sbjct: 680 VSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 720
Score = 191 bits (466), Expect = 2e-48
Identities = 91/223 (40%), Positives = 141/223 (63%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 562 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 622 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 681
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A + + K+G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 682 LLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 741
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 742 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 784
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 490 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 549
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 654
Score = 173 bits (420), Expect = 7e-43
Identities = 87/222 (39%), Positives = 128/222 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ +LL AAV+ AR TPLH+AS+ GN ++ LLL GA +
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T D PLH A+ + V L++ AP+ + TK G + LH+A + +L LLL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H D + +T LH+AA VA LL+K A+ A A NG TPLHIA +KN+++
Sbjct: 355 QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIK 414
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL++GA A +++G TP+H+AA GH + + L+ G
Sbjct: 415 VMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHG 456
Score = 172 bits (419), Expect = 1e-42
Identities = 82/225 (36%), Positives = 137/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+A + +H + +++LL++ V+ + T LH+A+ G+ +A +LL
Sbjct: 331 TKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G++ + +
Sbjct: 391 ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVS 450
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI+AR
Sbjct: 451 QLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLG 510
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 511 KADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 555
Score = 171 bits (417), Expect = 2e-42
Identities = 84/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A AKA TPLHIA + + + LLL+HGA ++A
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQA 428
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T P+H+AA + ++ + L+ H A T +G TALH+AA+ G +V L+
Sbjct: 429 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 488
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K+ TPLHI+A+ + + LL++GA A +G+TPLH++AR+ + A
Sbjct: 489 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVA 548
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL++GA + +K GFTPLH+AA+ G E+ LLL+
Sbjct: 549 AFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 586
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 398 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 458 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 517
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 518 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 577
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 578 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Score = 164 bits (398), Expect = 3e-40
Identities = 81/223 (36%), Positives = 129/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 588
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 589 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 648
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ K+G TPLH+AA+++
Sbjct: 649 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQED 708
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 709 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 751
Score = 161 bits (392), Expect = 2e-39
Identities = 81/226 (35%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +1
Query: 1 TVRGE-TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH 177
T R + TP+H+A++ + +++++LL GA ++AK R+ TPLH +R G+ + +LL
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDR 323
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A + + T + +PLH+A + + + L++HN P+ T TALH+AA G+ KVA
Sbjct: 324 AAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVA 383
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL A P+ NG TPLHIA + ++ V LL+ GA +AV ++G TP+H+AA
Sbjct: 384 KVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM 443
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ +GA N + G T LH+AA+ G E+ L++ G
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Score = 155 bits (376), Expect = 2e-37
Identities = 79/222 (35%), Positives = 123/222 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AR+ H ++ +LL A + +K + +PLH+A++ +++ LLLQH V
Sbjct: 301 GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 360
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ VA L++ A A GFT LH+A K +KV LLL
Sbjct: 361 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL 420
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA+ ++G+TP+H+AA + + L+ GA G T LH+AAR Q E
Sbjct: 421 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE 480
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L++ GA A++K TPLH++A+ G ++ LL+ G
Sbjct: 481 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG 522
Score = 153 bits (371), Expect = 6e-37
Identities = 79/223 (35%), Positives = 130/223 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L+ NGA V A+++ TPL++A++ ++++ LL +G
Sbjct: 104 TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNG 163
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A T D + PL +A +Q + V + L+E++ K ALH+AA+ + K A
Sbjct: 164 ASQSLATEDGFTPLAVALQQGHDQVVSLLLEND----TKGKVRLPALHIAARKDDTKAAA 219
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL + D K+G TPLHIAA Y VAT LL + A A+N TPLH+A+++
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA +A+++ G TPLH A+ GH ++ +LL+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Score = 147 bits (356), Expect = 4e-35
Identities = 78/211 (36%), Positives = 117/211 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 598 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 657
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA + + K G T LHLAA+ + VA +L+
Sbjct: 658 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLV 717
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 718 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 777
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 778 IINVLLQNNASPNELTVNGNTALGIARRLGY 808
Score = 143 bits (347), Expect = 5e-34
Identities = 77/222 (34%), Positives = 120/222 (54%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + +++ TPLHIA+ GN+++A LLL A V
Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLH+A+K+ N ++ L++ A + A T+ G T LH A+ G+ +V +LL A
Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++PLH+A Q D LL+ V + T LH+AA + A
Sbjct: 326 PILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Score = 142 bits (344), Expect = 1e-33
Identities = 77/222 (34%), Positives = 130/222 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H +++ LL+ A V+A ++ T LHIAS G ++ +L+ +GA+V
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ +V L+++ A + T+ GFT L +A + G+ +V +LLL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D GK + LHIAA+ D A LL+ +A +K+G TPLHIAA +
Sbjct: 194 EN----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNIN 249
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A + ++ TPLH+A+++G+ M LLL+ G
Sbjct: 250 VATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Score = 137 bits (331), Expect = 4e-32
Identities = 72/185 (38%), Positives = 99/185 (53%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 691 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 750
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 751 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 810
Query: 550 TAATL 564
TL
Sbjct: 811 VVDTL 815
Score = 132 bits (320), Expect = 1e-30
Identities = 81/220 (36%), Positives = 118/220 (53%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA H + ++NG + + LH+AS+ G+V++ LLQ A+V A T
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L+ + A + A ++ GFT L++AA+ +L+V LL +GA+
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q V + LLE D K K LHIAARK+ + AA LL+
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLLLEN--DTK--GKVRLPALHIAARKDDTKAAALLLQ 223
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ ESK+GFTPLH+AA G+ + LLL F
Sbjct: 224 NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Score = 131 bits (316), Expect = 3e-30
Identities = 74/223 (33%), Positives = 117/223 (52%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H ++ +LL N + K + R LHIA+R + A LLLQ+
Sbjct: 170 TEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQND 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + + PLHIAA N +VA L+ A + T + T LH+A+K GN +
Sbjct: 226 NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVK 285
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D ++G+TPLH A+ + V LL++ A + KNG +PLH+A + +
Sbjct: 286 LLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGD 345
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL++ + + T LH+AA GH ++ +LL+
Sbjct: 346 HLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Score = 110 bits (264), Expect = 6e-24
Identities = 58/155 (37%), Positives = 88/155 (56%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G VHLAA+ H D++ +LL A V + TPLH+A++ V++A +L+ G
Sbjct: 661 TRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 720
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A T Y PLH+ N + L++H+A + A TK G+T LH AA+ G+ + N
Sbjct: 721 AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN 780
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
+LL + A+P++ NG T L IA + +V TL
Sbjct: 781 VLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/122 (36%), Positives = 70/122 (57%)
Frame = +1
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
AA+ G+L+ A + +G + +NG+ LH+A++ V + LL++ A+ A K G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 508 HTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+T LHIA+ Q E L+ GA NA+S+ GFTPL++AAQ+ H E+ LL+ G
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 688 FA 693
A
Sbjct: 168 LA 169
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 643
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Score = 186 bits (452), Expect = 1e-46
Identities = 97/221 (43%), Positives = 136/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 560 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 619
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 620 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 679
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A + +G TPLHLAAQ+ + +L+ G
Sbjct: 680 VSLLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQG 715
Score = 182 bits (444), Expect = 9e-46
Identities = 90/223 (40%), Positives = 138/223 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 562 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 622 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 681
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A +G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 682 LLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 736
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 737 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 779
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 490 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 549
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 654
Score = 173 bits (420), Expect = 7e-43
Identities = 87/222 (39%), Positives = 128/222 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ +LL AAV+ AR TPLH+AS+ GN ++ LLL GA +
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T D PLH A+ + V L++ AP+ + TK G + LH+A + +L LLL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H D + +T LH+AA VA LL+K A+ A A NG TPLHIA +KN+++
Sbjct: 355 QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIK 414
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL++GA A +++G TP+H+AA GH + + L+ G
Sbjct: 415 VMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHG 456
Score = 172 bits (419), Expect = 1e-42
Identities = 82/225 (36%), Positives = 137/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+A + +H + +++LL++ V+ + T LH+A+ G+ +A +LL
Sbjct: 331 TKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G++ + +
Sbjct: 391 ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVS 450
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI+AR
Sbjct: 451 QLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLG 510
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 511 KADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 555
Score = 171 bits (417), Expect = 2e-42
Identities = 84/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A AKA TPLHIA + + + LLL+HGA ++A
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQA 428
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T P+H+AA + ++ + L+ H A T +G TALH+AA+ G +V L+
Sbjct: 429 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 488
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K+ TPLHI+A+ + + LL++GA A +G+TPLH++AR+ + A
Sbjct: 489 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVA 548
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL++GA + +K GFTPLH+AA+ G E+ LLL+
Sbjct: 549 AFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 586
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 398 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 458 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 517
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 518 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 577
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 578 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Score = 161 bits (392), Expect = 2e-39
Identities = 81/226 (35%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +1
Query: 1 TVRGE-TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH 177
T R + TP+H+A++ + +++++LL GA ++AK R+ TPLH +R G+ + +LL
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDR 323
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A + + T + +PLH+A + + + L++HN P+ T TALH+AA G+ KVA
Sbjct: 324 AAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVA 383
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL A P+ NG TPLHIA + ++ V LL+ GA +AV ++G TP+H+AA
Sbjct: 384 KVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM 443
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ +GA N + G T LH+AA+ G E+ L++ G
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Score = 156 bits (379), Expect = 7e-38
Identities = 80/223 (35%), Positives = 128/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 588
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 589 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 648
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ +G TPLH+AA+++
Sbjct: 649 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQED 703
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 704 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 746
Score = 155 bits (376), Expect = 2e-37
Identities = 79/222 (35%), Positives = 123/222 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AR+ H ++ +LL A + +K + +PLH+A++ +++ LLLQH V
Sbjct: 301 GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 360
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ VA L++ A A GFT LH+A K +KV LLL
Sbjct: 361 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL 420
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA+ ++G+TP+H+AA + + L+ GA G T LH+AAR Q E
Sbjct: 421 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE 480
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L++ GA A++K TPLH++A+ G ++ LL+ G
Sbjct: 481 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG 522
Score = 153 bits (371), Expect = 6e-37
Identities = 79/223 (35%), Positives = 130/223 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L+ NGA V A+++ TPL++A++ ++++ LL +G
Sbjct: 104 TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNG 163
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A T D + PL +A +Q + V + L+E++ K ALH+AA+ + K A
Sbjct: 164 ASQSLATEDGFTPLAVALQQGHDQVVSLLLEND----TKGKVRLPALHIAARKDDTKAAA 219
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL + D K+G TPLHIAA Y VAT LL + A A+N TPLH+A+++
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA +A+++ G TPLH A+ GH ++ +LL+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Score = 143 bits (347), Expect = 5e-34
Identities = 77/222 (34%), Positives = 120/222 (54%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + +++ TPLHIA+ GN+++A LLL A V
Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLH+A+K+ N ++ L++ A + A T+ G T LH A+ G+ +V +LL A
Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++PLH+A Q D LL+ V + T LH+AA + A
Sbjct: 326 PILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Score = 142 bits (344), Expect = 1e-33
Identities = 77/222 (34%), Positives = 130/222 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H +++ LL+ A V+A ++ T LHIAS G ++ +L+ +GA+V
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ +V L+++ A + T+ GFT L +A + G+ +V +LLL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D GK + LHIAA+ D A LL+ +A +K+G TPLHIAA +
Sbjct: 194 EN----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNIN 249
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A + ++ TPLH+A+++G+ M LLL+ G
Sbjct: 250 VATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Score = 138 bits (333), Expect = 3e-32
Identities = 77/211 (36%), Positives = 116/211 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 598 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 657
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA ++ G T LHLAA+ + VA +L+
Sbjct: 658 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLV 712
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 713 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 772
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 773 IINVLLQNNASPNELTVNGNTALGIARRLGY 803
Score = 134 bits (325), Expect = 2e-31
Identities = 73/185 (39%), Positives = 101/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 691 SGLT-----PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 745
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 746 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 805
Query: 550 TAATL 564
TL
Sbjct: 806 VVDTL 810
Score = 132 bits (320), Expect = 1e-30
Identities = 81/220 (36%), Positives = 118/220 (53%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA H + ++NG + + LH+AS+ G+V++ LLQ A+V A T
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L+ + A + A ++ GFT L++AA+ +L+V LL +GA+
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q V + LLE D K K LHIAARK+ + AA LL+
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLLLEN--DTK--GKVRLPALHIAARKDDTKAAALLLQ 223
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ ESK+GFTPLH+AA G+ + LLL F
Sbjct: 224 NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Score = 131 bits (316), Expect = 3e-30
Identities = 74/223 (33%), Positives = 117/223 (52%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H ++ +LL N + K + R LHIA+R + A LLLQ+
Sbjct: 170 TEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQND 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + + PLHIAA N +VA L+ A + T + T LH+A+K GN +
Sbjct: 226 NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVK 285
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D ++G+TPLH A+ + V LL++ A + KNG +PLH+A + +
Sbjct: 286 LLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGD 345
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL++ + + T LH+AA GH ++ +LL+
Sbjct: 346 HLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Score = 93.5 bits (222), Expect = 7e-19
Identities = 47/121 (38%), Positives = 70/121 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G TP+HLAA+ + ++ +L+ GA V+A+ + TPLH+ GN+ I LLQH A
Sbjct: 690 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 749
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A T + Y PLH AA+Q + + L+++NA T G TAL +A + G + V +
Sbjct: 750 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 809
Query: 364 L 366
L
Sbjct: 810 L 810
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/122 (36%), Positives = 70/122 (57%)
Frame = +1
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
AA+ G+L+ A + +G + +NG+ LH+A++ V + LL++ A+ A K G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 508 HTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+T LHIA+ Q E L+ GA NA+S+ GFTPL++AAQ+ H E+ LL+ G
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 688 FA 693
A
Sbjct: 168 LA 169
Score = 52.0 bits (119), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+ + I+ LL++ A V AK + TPLH A++ G+ I +LLQ+
Sbjct: 722 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 781
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAAL-IEHNAPLTATT 300
A +T + L IA + V L I +T TT
Sbjct: 782 ASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTT 822
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 79 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 138
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 139 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 198
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 199 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 258
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 259 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 299
Score = 186 bits (452), Expect = 1e-46
Identities = 97/221 (43%), Positives = 136/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 115 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 174
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 175 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 234
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 235 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 294
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A + +G TPLHLAAQ+ + +L+ G
Sbjct: 295 VSLLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQG 330
Score = 182 bits (444), Expect = 9e-46
Identities = 90/223 (40%), Positives = 138/223 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 177 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 236
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 237 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 296
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A +G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 297 LLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 351
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 352 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 394
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 45 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 104
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 105 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 164
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 165 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 224
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 225 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 269
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 13 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 72
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 73 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 192
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 193 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 236
Score = 158 bits (383), Expect = 2e-38
Identities = 79/201 (39%), Positives = 120/201 (59%)
Frame = +1
Query: 67 LLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHN 246
LL A AKA TPLHIA + + + LLL+HGA ++A+T P+H+AA +
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 247 HDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHI 426
++ + L+ H A T +G TALH+AA+ G +V L+ GA + K+ TPLHI
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 120
Query: 427 AAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAG 606
+A+ + + LL++GA A +G+TPLH++AR+ + AA LL++GA + +K G
Sbjct: 121 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG 180
Query: 607 FTPLHLAAQQGHTEMCALLLE 669
FTPLH+AA+ G E+ LLL+
Sbjct: 181 FTPLHVAAKYGKLEVANLLLQ 201
Score = 156 bits (379), Expect = 7e-38
Identities = 80/223 (35%), Positives = 128/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 144 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 203
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 204 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 263
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ +G TPLH+AA+++
Sbjct: 264 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQED 318
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 319 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 361
Score = 138 bits (333), Expect = 3e-32
Identities = 77/211 (36%), Positives = 116/211 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 213 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 272
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA ++ G T LHLAA+ + VA +L+
Sbjct: 273 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLV 327
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 328 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 387
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 388 IINVLLQNNASPNELTVNGNTALGIARRLGY 418
Score = 137 bits (332), Expect = 3e-32
Identities = 67/170 (39%), Positives = 104/170 (61%)
Frame = +1
Query: 166 LLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
LL A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G+
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+ + + L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 120
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+AR + + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 121 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 170
Score = 134 bits (325), Expect = 2e-31
Identities = 73/185 (39%), Positives = 101/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 246 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 305
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 306 SGLT-----PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 360
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 361 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 420
Query: 550 TAATL 564
TL
Sbjct: 421 VVDTL 425
Score = 93.5 bits (222), Expect = 7e-19
Identities = 47/121 (38%), Positives = 70/121 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G TP+HLAA+ + ++ +L+ GA V+A+ + TPLH+ GN+ I LLQH A
Sbjct: 305 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 364
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A T + Y PLH AA+Q + + L+++NA T G TAL +A + G + V +
Sbjct: 365 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 424
Query: 364 L 366
L
Sbjct: 425 L 425
Score = 52.0 bits (119), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+ + I+ LL++ A V AK + TPLH A++ G+ I +LLQ+
Sbjct: 337 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 396
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAAL-IEHNAPLTATT 300
A +T + L IA + V L I +T TT
Sbjct: 397 ASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTT 437
Score = 35.1 bits (77), Expect = 0.27
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = +1
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 42
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 643
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Score = 186 bits (452), Expect = 1e-46
Identities = 97/221 (43%), Positives = 136/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 560 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 619
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 620 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 679
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A + +G TPLHLAAQ+ + +L+ G
Sbjct: 680 VSLLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQG 715
Score = 182 bits (444), Expect = 9e-46
Identities = 90/223 (40%), Positives = 138/223 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 562 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 622 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 681
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A +G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 682 LLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 736
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 737 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 779
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 490 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 549
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 654
Score = 173 bits (420), Expect = 7e-43
Identities = 87/222 (39%), Positives = 128/222 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ +LL AAV+ AR TPLH+AS+ GN ++ LLL GA +
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T D PLH A+ + V L++ AP+ + TK G + LH+A + +L LLL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H D + +T LH+AA VA LL+K A+ A A NG TPLHIA +KN+++
Sbjct: 355 QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIK 414
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL++GA A +++G TP+H+AA GH + + L+ G
Sbjct: 415 VMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHG 456
Score = 172 bits (419), Expect = 1e-42
Identities = 82/225 (36%), Positives = 137/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+A + +H + +++LL++ V+ + T LH+A+ G+ +A +LL
Sbjct: 331 TKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G++ + +
Sbjct: 391 ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVS 450
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI+AR
Sbjct: 451 QLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLG 510
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 511 KADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 555
Score = 171 bits (417), Expect = 2e-42
Identities = 84/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A AKA TPLHIA + + + LLL+HGA ++A
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQA 428
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T P+H+AA + ++ + L+ H A T +G TALH+AA+ G +V L+
Sbjct: 429 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 488
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K+ TPLHI+A+ + + LL++GA A +G+TPLH++AR+ + A
Sbjct: 489 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVA 548
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL++GA + +K GFTPLH+AA+ G E+ LLL+
Sbjct: 549 AFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 586
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 398 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 458 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 517
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 518 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 577
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 578 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Score = 161 bits (392), Expect = 2e-39
Identities = 81/226 (35%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +1
Query: 1 TVRGE-TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH 177
T R + TP+H+A++ + +++++LL GA ++AK R+ TPLH +R G+ + +LL
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDR 323
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A + + T + +PLH+A + + + L++HN P+ T TALH+AA G+ KVA
Sbjct: 324 AAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVA 383
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL A P+ NG TPLHIA + ++ V LL+ GA +AV ++G TP+H+AA
Sbjct: 384 KVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM 443
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ +GA N + G T LH+AA+ G E+ L++ G
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Score = 156 bits (379), Expect = 7e-38
Identities = 80/223 (35%), Positives = 128/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 588
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 589 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 648
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ +G TPLH+AA+++
Sbjct: 649 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQED 703
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 704 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 746
Score = 155 bits (376), Expect = 2e-37
Identities = 79/222 (35%), Positives = 123/222 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AR+ H ++ +LL A + +K + +PLH+A++ +++ LLLQH V
Sbjct: 301 GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 360
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ VA L++ A A GFT LH+A K +KV LLL
Sbjct: 361 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL 420
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA+ ++G+TP+H+AA + + L+ GA G T LH+AAR Q E
Sbjct: 421 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE 480
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L++ GA A++K TPLH++A+ G ++ LL+ G
Sbjct: 481 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG 522
Score = 153 bits (371), Expect = 6e-37
Identities = 79/223 (35%), Positives = 130/223 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L+ NGA V A+++ TPL++A++ ++++ LL +G
Sbjct: 104 TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNG 163
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A T D + PL +A +Q + V + L+E++ K ALH+AA+ + K A
Sbjct: 164 ASQSLATEDGFTPLAVALQQGHDQVVSLLLEND----TKGKVRLPALHIAARKDDTKAAA 219
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL + D K+G TPLHIAA Y VAT LL + A A+N TPLH+A+++
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA +A+++ G TPLH A+ GH ++ +LL+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Score = 143 bits (347), Expect = 5e-34
Identities = 77/222 (34%), Positives = 120/222 (54%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + +++ TPLHIA+ GN+++A LLL A V
Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLH+A+K+ N ++ L++ A + A T+ G T LH A+ G+ +V +LL A
Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++PLH+A Q D LL+ V + T LH+AA + A
Sbjct: 326 PILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Score = 142 bits (344), Expect = 1e-33
Identities = 77/222 (34%), Positives = 130/222 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H +++ LL+ A V+A ++ T LHIAS G ++ +L+ +GA+V
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ +V L+++ A + T+ GFT L +A + G+ +V +LLL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D GK + LHIAA+ D A LL+ +A +K+G TPLHIAA +
Sbjct: 194 EN----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNIN 249
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A + ++ TPLH+A+++G+ M LLL+ G
Sbjct: 250 VATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Score = 138 bits (333), Expect = 3e-32
Identities = 77/211 (36%), Positives = 116/211 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 598 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 657
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA ++ G T LHLAA+ + VA +L+
Sbjct: 658 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLV 712
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 713 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 772
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 773 IINVLLQNNASPNELTVNGNTALGIARRLGY 803
Score = 134 bits (325), Expect = 2e-31
Identities = 73/185 (39%), Positives = 101/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 691 SGLT-----PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 745
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 746 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 805
Query: 550 TAATL 564
TL
Sbjct: 806 VVDTL 810
Score = 132 bits (320), Expect = 1e-30
Identities = 81/220 (36%), Positives = 118/220 (53%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA H + ++NG + + LH+AS+ G+V++ LLQ A+V A T
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L+ + A + A ++ GFT L++AA+ +L+V LL +GA+
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q V + LLE D K K LHIAARK+ + AA LL+
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLLLEN--DTK--GKVRLPALHIAARKDDTKAAALLLQ 223
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ ESK+GFTPLH+AA G+ + LLL F
Sbjct: 224 NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Score = 131 bits (316), Expect = 3e-30
Identities = 74/223 (33%), Positives = 117/223 (52%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H ++ +LL N + K + R LHIA+R + A LLLQ+
Sbjct: 170 TEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQND 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + + PLHIAA N +VA L+ A + T + T LH+A+K GN +
Sbjct: 226 NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVK 285
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D ++G+TPLH A+ + V LL++ A + KNG +PLH+A + +
Sbjct: 286 LLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGD 345
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL++ + + T LH+AA GH ++ +LL+
Sbjct: 346 HLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Score = 93.5 bits (222), Expect = 7e-19
Identities = 47/121 (38%), Positives = 70/121 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G TP+HLAA+ + ++ +L+ GA V+A+ + TPLH+ GN+ I LLQH A
Sbjct: 690 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 749
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A T + Y PLH AA+Q + + L+++NA T G TAL +A + G + V +
Sbjct: 750 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 809
Query: 364 L 366
L
Sbjct: 810 L 810
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/122 (36%), Positives = 70/122 (57%)
Frame = +1
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
AA+ G+L+ A + +G + +NG+ LH+A++ V + LL++ A+ A K G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 508 HTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+T LHIA+ Q E L+ GA NA+S+ GFTPL++AAQ+ H E+ LL+ G
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 688 FA 693
A
Sbjct: 168 LA 169
Score = 52.0 bits (119), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+ + I+ LL++ A V AK + TPLH A++ G+ I +LLQ+
Sbjct: 722 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 781
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAAL-IEHNAPLTATT 300
A +T + L IA + V L I +T TT
Sbjct: 782 ASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTT 822
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 79 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 138
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 139 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 198
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 199 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 258
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 259 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 299
Score = 186 bits (452), Expect = 1e-46
Identities = 97/221 (43%), Positives = 136/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 115 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 174
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 175 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 234
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 235 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 294
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A + +G TPLHLAAQ+ + +L+ G
Sbjct: 295 VSLLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQG 330
Score = 182 bits (444), Expect = 9e-46
Identities = 90/223 (40%), Positives = 138/223 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 177 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 236
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 237 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 296
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A +G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 297 LLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 351
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 352 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 394
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 45 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 104
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 105 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 164
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 165 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 224
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 225 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 269
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 13 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 72
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 73 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 192
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 193 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 236
Score = 158 bits (383), Expect = 2e-38
Identities = 79/201 (39%), Positives = 120/201 (59%)
Frame = +1
Query: 67 LLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHN 246
LL A AKA TPLHIA + + + LLL+HGA ++A+T P+H+AA +
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 247 HDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHI 426
++ + L+ H A T +G TALH+AA+ G +V L+ GA + K+ TPLHI
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 120
Query: 427 AAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAG 606
+A+ + + LL++GA A +G+TPLH++AR+ + AA LL++GA + +K G
Sbjct: 121 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG 180
Query: 607 FTPLHLAAQQGHTEMCALLLE 669
FTPLH+AA+ G E+ LLL+
Sbjct: 181 FTPLHVAAKYGKLEVANLLLQ 201
Score = 156 bits (379), Expect = 7e-38
Identities = 80/223 (35%), Positives = 128/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 144 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 203
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 204 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 263
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ +G TPLH+AA+++
Sbjct: 264 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQED 318
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 319 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 361
Score = 138 bits (333), Expect = 3e-32
Identities = 77/211 (36%), Positives = 116/211 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 213 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 272
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA ++ G T LHLAA+ + VA +L+
Sbjct: 273 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLV 327
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 328 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 387
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 388 IINVLLQNNASPNELTVNGNTALGIARRLGY 418
Score = 137 bits (332), Expect = 3e-32
Identities = 67/170 (39%), Positives = 104/170 (61%)
Frame = +1
Query: 166 LLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
LL A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G+
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+ + + L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 120
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+AR + + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 121 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 170
Score = 134 bits (325), Expect = 2e-31
Identities = 73/185 (39%), Positives = 101/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 246 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 305
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 306 SGLT-----PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 360
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 361 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 420
Query: 550 TAATL 564
TL
Sbjct: 421 VVDTL 425
Score = 93.5 bits (222), Expect = 7e-19
Identities = 47/121 (38%), Positives = 70/121 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G TP+HLAA+ + ++ +L+ GA V+A+ + TPLH+ GN+ I LLQH A
Sbjct: 305 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 364
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A T + Y PLH AA+Q + + L+++NA T G TAL +A + G + V +
Sbjct: 365 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 424
Query: 364 L 366
L
Sbjct: 425 L 425
Score = 52.0 bits (119), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+ + I+ LL++ A V AK + TPLH A++ G+ I +LLQ+
Sbjct: 337 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 396
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAAL-IEHNAPLTATT 300
A +T + L IA + V L I +T TT
Sbjct: 397 ASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTT 437
Score = 35.1 bits (77), Expect = 0.27
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = +1
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 42
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 277 bits (679), Expect = 3e-74
Identities = 130/221 (58%), Positives = 168/221 (76%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
VRGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANL
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQ
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 643
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
M+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Score = 186 bits (452), Expect = 1e-46
Identities = 97/221 (43%), Positives = 136/221 (61%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 560 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 619
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 620 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 679
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A + +G TPLHLAAQ+ + +L+ G
Sbjct: 680 VSLLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQG 715
Score = 182 bits (444), Expect = 9e-46
Identities = 90/223 (40%), Positives = 138/223 (61%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 562 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 622 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 681
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A +G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 682 LLLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 736
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 737 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 779
Score = 177 bits (432), Expect = 3e-44
Identities = 91/225 (40%), Positives = 131/225 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AA H +I+ L+ +GA+ +T LH+A+R G ++ L+Q G
Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLHI+A+ D+ L++ A A T G+T LHL+A+ G+ VA
Sbjct: 490 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 549
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL HGA+ K G TPLH+AA+Y + VA LL+K A A K+G TPLH+AA +
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LL+ GA +A +K G+TPLH+AA++ ++ LLE G
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYG 654
Score = 173 bits (420), Expect = 7e-43
Identities = 87/222 (39%), Positives = 128/222 (57%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ +LL AAV+ AR TPLH+AS+ GN ++ LLL GA +
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T D PLH A+ + V L++ AP+ + TK G + LH+A + +L LLL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H D + +T LH+AA VA LL+K A+ A A NG TPLHIA +KN+++
Sbjct: 355 QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIK 414
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL++GA A +++G TP+H+AA GH + + L+ G
Sbjct: 415 VMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHG 456
Score = 172 bits (419), Expect = 1e-42
Identities = 82/225 (36%), Positives = 137/225 (60%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+A + +H + +++LL++ V+ + T LH+A+ G+ +A +LL
Sbjct: 331 TKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ A + + PLHIA K++ V L++H A + A T+ G T +H+AA G++ + +
Sbjct: 391 ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVS 450
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ HGA+P+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI+AR
Sbjct: 451 QLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLG 510
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + LL+ GA NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 511 KADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 555
Score = 171 bits (417), Expect = 2e-42
Identities = 84/218 (38%), Positives = 130/218 (59%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H+AA H + ++LL A AKA TPLHIA + + + LLL+HGA ++A
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQA 428
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T P+H+AA + ++ + L+ H A T +G TALH+AA+ G +V L+
Sbjct: 429 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 488
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K+ TPLHI+A+ + + LL++GA A +G+TPLH++AR+ + A
Sbjct: 489 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVA 548
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL++GA + +K GFTPLH+AA+ G E+ LLL+
Sbjct: 549 AFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 586
Score = 165 bits (400), Expect = 2e-40
Identities = 80/224 (35%), Positives = 129/224 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + N ++ +LL++GA+++A TP+H+A+ +G+V+I L+ HGA
Sbjct: 398 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
LH+AA+ +V L++ A + A K T LH++A+ G +
Sbjct: 458 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 517
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL GA+P+ A +G TPLH++A+ + VA LL+ GA K G TPLH+AA+ +
Sbjct: 518 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 577
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ A +A K+G TPLH+AA + ++ LLL+ G
Sbjct: 578 LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Score = 161 bits (392), Expect = 2e-39
Identities = 81/226 (35%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +1
Query: 1 TVRGE-TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH 177
T R + TP+H+A++ + +++++LL GA ++AK R+ TPLH +R G+ + +LL
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDR 323
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A + + T + +PLH+A + + + L++HN P+ T TALH+AA G+ KVA
Sbjct: 324 AAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVA 383
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL A P+ NG TPLHIA + ++ V LL+ GA +AV ++G TP+H+AA
Sbjct: 384 KVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM 443
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ +GA N + G T LH+AA+ G E+ L++ G
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Score = 156 bits (379), Expect = 7e-38
Identities = 80/223 (35%), Positives = 128/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 588
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 589 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 648
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ +G TPLH+AA+++
Sbjct: 649 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQED 703
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 704 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 746
Score = 155 bits (376), Expect = 2e-37
Identities = 79/222 (35%), Positives = 123/222 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AR+ H ++ +LL A + +K + +PLH+A++ +++ LLLQH V
Sbjct: 301 GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 360
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T D+ LH+AA ++ VA L++ A A GFT LH+A K +KV LLL
Sbjct: 361 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL 420
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA+ ++G+TP+H+AA + + L+ GA G T LH+AAR Q E
Sbjct: 421 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE 480
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L++ GA A++K TPLH++A+ G ++ LL+ G
Sbjct: 481 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG 522
Score = 153 bits (371), Expect = 6e-37
Identities = 79/223 (35%), Positives = 130/223 (58%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+A+ A +++++L+ NGA V A+++ TPL++A++ ++++ LL +G
Sbjct: 104 TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNG 163
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A T D + PL +A +Q + V + L+E++ K ALH+AA+ + K A
Sbjct: 164 ASQSLATEDGFTPLAVALQQGHDQVVSLLLEND----TKGKVRLPALHIAARKDDTKAAA 219
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL + D K+G TPLHIAA Y VAT LL + A A+N TPLH+A+++
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA +A+++ G TPLH A+ GH ++ +LL+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Score = 143 bits (347), Expect = 5e-34
Identities = 77/222 (34%), Positives = 120/222 (54%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + +++ TPLHIA+ GN+++A LLL A V
Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLH+A+K+ N ++ L++ A + A T+ G T LH A+ G+ +V +LL A
Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++PLH+A Q D LL+ V + T LH+AA + A
Sbjct: 326 PILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A NA++ GFTPLH+A ++ ++ LLL+ G Q
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Score = 142 bits (344), Expect = 1e-33
Identities = 77/222 (34%), Positives = 130/222 (58%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H +++ LL+ A V+A ++ T LHIAS G ++ +L+ +GA+V
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + + PL++AA++++ +V L+++ A + T+ GFT L +A + G+ +V +LLL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D GK + LHIAA+ D A LL+ +A +K+G TPLHIAA +
Sbjct: 194 EN----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNIN 249
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A + ++ TPLH+A+++G+ M LLL+ G
Sbjct: 250 VATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Score = 138 bits (333), Expect = 3e-32
Identities = 77/211 (36%), Positives = 116/211 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 598 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 657
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA ++ G T LHLAA+ + VA +L+
Sbjct: 658 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLV 712
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 713 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 772
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 773 IINVLLQNNASPNELTVNGNTALGIARRLGY 803
Score = 134 bits (325), Expect = 2e-31
Identities = 73/185 (39%), Positives = 101/185 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+T PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 691 SGLT-----PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 745
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 746 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 805
Query: 550 TAATL 564
TL
Sbjct: 806 VVDTL 810
Score = 132 bits (320), Expect = 1e-30
Identities = 81/220 (36%), Positives = 118/220 (53%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AARA H + ++NG + + LH+AS+ G+V++ LLQ A+V A T
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIA+ +V L+ + A + A ++ GFT L++AA+ +L+V LL +GA+
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q V + LLE D K K LHIAARK+ + AA LL+
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLLLEN--DTK--GKVRLPALHIAARKDDTKAAALLLQ 223
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ ESK+GFTPLH+AA G+ + LLL F
Sbjct: 224 NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Score = 131 bits (316), Expect = 3e-30
Identities = 74/223 (33%), Positives = 117/223 (52%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H ++ +LL N + K + R LHIA+R + A LLLQ+
Sbjct: 170 TEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQND 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + + PLHIAA N +VA L+ A + T + T LH+A+K GN +
Sbjct: 226 NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVK 285
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D ++G+TPLH A+ + V LL++ A + KNG +PLH+A + +
Sbjct: 286 LLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGD 345
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL++ + + T LH+AA GH ++ +LL+
Sbjct: 346 HLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 388
Score = 93.5 bits (222), Expect = 7e-19
Identities = 47/121 (38%), Positives = 70/121 (57%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G TP+HLAA+ + ++ +L+ GA V+A+ + TPLH+ GN+ I LLQH A
Sbjct: 690 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 749
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A T + Y PLH AA+Q + + L+++NA T G TAL +A + G + V +
Sbjct: 750 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 809
Query: 364 L 366
L
Sbjct: 810 L 810
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/122 (36%), Positives = 70/122 (57%)
Frame = +1
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
AA+ G+L+ A + +G + +NG+ LH+A++ V + LL++ A+ A K G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 508 HTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+T LHIA+ Q E L+ GA NA+S+ GFTPL++AAQ+ H E+ LL+ G
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 688 FA 693
A
Sbjct: 168 LA 169
Score = 52.0 bits (119), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+ + I+ LL++ A V AK + TPLH A++ G+ I +LLQ+
Sbjct: 722 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 781
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAAL-IEHNAPLTATT 300
A +T + L IA + V L I +T TT
Sbjct: 782 ASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTT 822
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 275 bits (675), Expect = 9e-74
Identities = 129/220 (58%), Positives = 167/220 (75%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RGET +H+AAR+ +++R L+++GA VEAKA++ QTPLHI++RLG DI LLQ GA
Sbjct: 9 RGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGAS 68
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A T Y PLH++A++ + DVAA L++H A L+ TTKKGFT LH+AAKYG L+VANLL
Sbjct: 69 PNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 128
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L A+PD AGK+G+TPLH+AA YD Q VA LL++GA A AKNG+TPLHIAA+KNQM
Sbjct: 129 LQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQM 188
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ A TLLEYGA NA ++ G +HLAAQ+GH +M +LLL
Sbjct: 189 DIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 228
Score = 197 bits (480), Expect = 4e-50
Identities = 99/221 (44%), Positives = 138/221 (62%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H++AR DI++ LL+ GA+ A TPLH+++R G+ D+A LL HGA +
Sbjct: 44 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 103
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + PLH+AAK +VA L++ +A A K G T LH+AA Y N KVA LLL
Sbjct: 104 ITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 163
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA+P A KNG TPLHIAA+ +Q +ATTLLE GADA AV + G +H+AA++ ++
Sbjct: 164 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 223
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL A N +K+G TPLHLAAQ+ + +L+ G
Sbjct: 224 VSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 264
Score = 191 bits (466), Expect = 2e-48
Identities = 91/223 (40%), Positives = 141/223 (63%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ ++ +LL+ A+ +A + TPLH+A+ N +A+LLL G
Sbjct: 106 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 165
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + Y PLHIAAK++ D+A L+E+ A A T++G ++HLAA+ G++ + +
Sbjct: 166 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 225
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL A + + K+G+TPLH+AAQ D+ VA L+ +GA A K G+TPLH+
Sbjct: 226 LLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 285
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ LL++ A NA++K G+TPLH AAQQGHT + +LL+
Sbjct: 286 NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 328
Score = 164 bits (398), Expect = 3e-40
Identities = 81/223 (36%), Positives = 129/223 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HL+AR H D+ LL +GA++ ++ TPLH+A++ G +++A LLLQ
Sbjct: 73 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 132
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A PLH+AA N VA L++ A A K G+T LH+AAK + +A
Sbjct: 133 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 192
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +GA + + G+ +H+AAQ + + LL + A+ K+G TPLH+AA+++
Sbjct: 193 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQED 252
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ A L+ GA +A++K G+TPLH+ G+ ++ LL+
Sbjct: 253 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 295
Score = 156 bits (379), Expect = 7e-38
Identities = 79/188 (42%), Positives = 112/188 (59%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
+T LH+A+R G ++ L+Q GA V A D PLHI+A+ D+ L++ A
Sbjct: 11 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN 70
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A T G+T LHL+A+ G+ VA LL HGA+ K G TPLH+AA+Y + VA LL+
Sbjct: 71 AATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 130
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
K A A K+G TPLH+AA + + A LL+ GA +A +K G+TPLH+AA++ ++
Sbjct: 131 KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDI 190
Query: 652 CALLLEGG 675
LLE G
Sbjct: 191 ATTLLEYG 198
Score = 147 bits (356), Expect = 4e-35
Identities = 78/211 (36%), Positives = 117/211 (55%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA ++ + +LL GA+ A A+ TPLHIA++ +DIA LL++GAD
Sbjct: 142 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 201
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+T +H+AA++ + D+ + L+ NA + + K G T LHLAA+ + VA +L+
Sbjct: 202 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLV 261
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D K G TPLH+ Y + LL+ A A KNG+TPLH AA++
Sbjct: 262 NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTH 321
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ A N + G T L +A + G+
Sbjct: 322 IINVLLQNNASPNELTVNGNTALGIARRLGY 352
Score = 137 bits (331), Expect = 4e-32
Identities = 72/185 (38%), Positives = 99/185 (53%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA+ N DI LL GA A R+ +H+A++ G+VD+ LLL A+V
Sbjct: 175 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 234
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA++ +VA L+ A + A TK G+T LH+ YGN+K+ N LL
Sbjct: 235 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 294
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
H A + KNG TPLH AAQ + LL+ A + NG+T L IA R +
Sbjct: 295 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYIS 354
Query: 550 TAATL 564
TL
Sbjct: 355 VVDTL 359
Score = 110 bits (265), Expect = 4e-24
Identities = 69/211 (32%), Positives = 107/211 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G VHLAA+ H D++ +LL A V + TPLH+A++ V++A +L+ G
Sbjct: 205 TRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 264
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A T Y PLH+ N + L++H+A + A TK G+T LH AA+ G+ + N
Sbjct: 265 AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN 324
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL + A+P++ NG T L IA + +V TL K + + T H + N
Sbjct: 325 VLLQNNASPNELTVNGNTALGIARRLGYISVVDTL--KIVTEETMTTTTVTEKH---KMN 379
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
ET +L+ ++ G T +L Q
Sbjct: 380 VPETMNEVLDMSDDEGEDAMTGDTDKYLGPQ 410
Score = 107 bits (258), Expect = 3e-23
Identities = 52/128 (40%), Positives = 80/128 (62%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
L ++G TALH+AA+ G +V L+ GA + K+ TPLHI+A+ + + L
Sbjct: 3 LAHVPQRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQL 62
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L++GA A +G+TPLH++AR+ + AA LL++GA + +K GFTPLH+AA+ G
Sbjct: 63 LQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 122
Query: 646 EMCALLLE 669
E+ LLL+
Sbjct: 123 EVANLLLQ 130
Score = 84.6 bits (200), Expect = 3e-16
Identities = 40/92 (43%), Positives = 60/92 (65%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
+ G T LH+AA+ Q V L++ GA +A AK+ TPLHI+AR + + LL+ GA
Sbjct: 8 QRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 67
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
NA + +G+TPLHL+A++GH ++ A LL+ G
Sbjct: 68 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHG 99
Score = 48.8 bits (111), Expect = 2e-05
Identities = 24/61 (39%), Positives = 36/61 (59%)
Frame = +1
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
V + G T LH+AAR Q E L++ GA A++K TPLH++A+ G ++ LL+
Sbjct: 6 VPQRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQ 65
Query: 673 G 675
G
Sbjct: 66 G 66
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 239 bits (584), Expect = 1e-62
Identities = 114/221 (51%), Positives = 155/221 (70%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ ETP+H+AARA HT++ + LL+N A V AKA++ QTPLH A+R+G+ ++ LLL++ A
Sbjct: 435 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNA 494
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ T + PLHIAA++ + + AL+E A TKKGFT LH+AAKYG ++VA L
Sbjct: 495 NPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAEL 554
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A P+ AGKNG+TPLH+A ++ + LL +G + A NG+TPLHIAA++NQ
Sbjct: 555 LLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 614
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+E A +LL+YG NAES G TPLHLAAQ+GH EM ALLL
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Score = 180 bits (439), Expect = 4e-45
Identities = 93/221 (42%), Positives = 129/221 (58%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H AAR HT+++++LL N A TPLHIA+R G+V+ + LL+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+T + PLH+AAK VA L+E +A A K G T LH+A + NL + LLL
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 590
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G +P NG TPLHIAA+ +Q VA +LL+ G A A + G TPLH+AA++ E
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEM 650
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A N +K+G TPLHL AQ+GH + +L++ G
Sbjct: 651 VALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Score = 176 bits (429), Expect = 6e-44
Identities = 91/222 (40%), Positives = 131/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ ++LL GA+V + TPLHIASR GNV + LLL GA +
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T D PLH AA+ + ++ L++H AP+ A TK G + +H+AA+ +L LLL
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ A D + +TPLH+AA VA LL+KGA + A NG TPLHIA +KN +
Sbjct: 326 QYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVR 385
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA +A +++G TPLH+A+ GH + LL+ G
Sbjct: 386 VMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG 427
Score = 175 bits (425), Expect = 2e-43
Identities = 92/226 (40%), Positives = 130/226 (57%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AAR H I ILL +GA ++AK + +P+H+A++ ++D LLLQ+ A++
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD 333
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT DH PLH+AA +H VA L++ A + GFT LH+A K +++V LLL
Sbjct: 334 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 393
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA+ D ++G+TPLH+A+ + LL++GA TPLH+AAR E A
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA 453
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
LL+ A NA++K TPLH AA+ GHT M LLLE A
Sbjct: 454 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Score = 173 bits (422), Expect = 4e-43
Identities = 88/220 (40%), Positives = 134/220 (60%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A+R + ++R+LL GA +E K ++ TPLH A+R G+V I+ +LL HGA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+A T + +P+H+AA+ + D L++++A + T T LH+AA G+ +VA +LL
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 358
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA P+ NG TPLHIA + + V LL+ GA AV ++G TPLH+A+ +
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLP 418
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA N + TPLH+AA+ GHTE+ LL+
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 458
Score = 173 bits (420), Expect = 7e-43
Identities = 88/225 (39%), Positives = 133/225 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ + +LL A A + TPLH+A N+DI LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + Y PLHIAAKQ+ +VA +L+++ A + +G T LHLAA+ G+ ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 652
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL+ A + K+G+TPLH+ AQ VA L++ G A + G+TPLH+A+
Sbjct: 653 LLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 712
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL++ A NA++K G++PLH AAQQGHT++ LLL+ G
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 757
Score = 165 bits (401), Expect = 1e-40
Identities = 87/224 (38%), Positives = 125/224 (55%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + NH ++ +LL+ GA+++A TPLH+AS +G++ I LLQ GA
Sbjct: 369 LNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
PLH+AA+ + +VA L+++ A + A K T LH AA+ G+ + L
Sbjct: 429 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKL 488
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL + A P+ A G TPLHIAA+ LLEK A + K G TPLH+AA+ +
Sbjct: 489 LLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK 548
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LLE A NA K G TPLH+A + ++ LLL G
Sbjct: 549 VRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Score = 164 bits (398), Expect = 3e-40
Identities = 87/225 (38%), Positives = 129/225 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+A+ H I++ LL+ GA+ + +TPLH+A+R G+ ++A LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLH AA+ + ++ L+E+NA T G T LH+AA+ G+++
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVL 520
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL A+ K G TPLH+AA+Y + VA LLE+ A A KNG TPLH+A N
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL G ++ + G+TPLH+AA+Q E+ LL+ G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYG 625
Score = 162 bits (394), Expect = 1e-39
Identities = 86/223 (38%), Positives = 127/223 (56%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H D +R+LL+ A ++ + TPLH+A+ G+ +A +LL G
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + + PLHIA K+++ V L++ A + A T+ G T LH+A+ G+L +
Sbjct: 362 AKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVK 421
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL GA+P+ + TPLH+AA+ VA LL+ A A AK+ TPLH AAR
Sbjct: 422 NLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG 481
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A N + AG TPLH+AA++GH E LLE
Sbjct: 482 HTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 524
Score = 157 bits (381), Expect = 4e-38
Identities = 84/229 (36%), Positives = 131/229 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+AA A +++R L+ GA V A++++ TPL++A++ ++++ LL++G
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 134
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q + +V A LI + K ALH+AA+ + + A
Sbjct: 135 ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK----GKVRLPALHIAARNDDTRTAA 190
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL + PD K G TPLHIAA Y+ VA LL +GA +NG TPLHIA+R+
Sbjct: 191 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 250
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+ LL+ GA ++K TPLH AA+ GH + +LL+ G Q
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQ 299
Score = 157 bits (380), Expect = 5e-38
Identities = 76/223 (34%), Positives = 124/223 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AAR H + + LL A+ ++ TPLH+A++ G V +A LLL+
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + PLH+A +N D+ L+ + G+T LH+AAK ++VA
Sbjct: 560 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 619
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +G + + G+TPLH+AAQ + LL K A+ K+G TPLH+ A++
Sbjct: 620 SLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ A L+++G + +A ++ G+TPLH+A+ G+ ++ LL+
Sbjct: 680 HVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Score = 155 bits (377), Expect = 1e-37
Identities = 84/218 (38%), Positives = 120/218 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H + ++LL GA ++A TPLHIA + +V + LLL+ GA + A
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T PLH+A+ + + L++ A + K T LH+AA+ G+ +VA LL +
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 459
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + K+ TPLH AA+ + LLE A+ GHTPLHIAAR+ +ET
Sbjct: 460 KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A +K GFTPLH+AA+ G + LLLE
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 153 bits (371), Expect = 6e-37
Identities = 82/229 (35%), Positives = 125/229 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A N+ DI+++LL G + + A TPLHIA++ V++A LLQ+G
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+AA++ + ++ A L+ A K G T LHL A+ G++ VA++L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HG D + G TPLH+A+ Y + LL+ AD A K G++PLH AA++ +
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LL+ GA N S G TPL +A + G+ + +L T F L
Sbjct: 749 IVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVL 797
Score = 151 bits (367), Expect = 2e-36
Identities = 79/218 (36%), Positives = 123/218 (56%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + ++ TPLHIA+ N+++A LLL GA V
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 236
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLHIA+++ N + L++ A + TK T LH AA+ G+++++ +LL HGA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++P+H+AAQ D LL+ A+ + + TPLH+AA A
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKV 356
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA N+ + GFTPLH+A ++ H + LLL+ G
Sbjct: 357 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTG 394
Score = 136 bits (330), Expect = 6e-32
Identities = 77/225 (34%), Positives = 124/225 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H +++ L+ G K + R LHIA+R + A +LLQ+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLLQND 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ ++ + PLHIAA N +VA L+ A + T + G T LH+A++ GN+ +
Sbjct: 197 PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+ +TPLH AA+ ++ LL+ GA +A KNG +P+H+AA+ +
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGD 316
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+Y A + + TPLH+AA GH + +LL+ G
Sbjct: 317 HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 132 bits (318), Expect = 2e-30
Identities = 75/222 (33%), Positives = 120/222 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H ++ LL +E ++ T LHIA+ G ++ L+ +GA+V
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 104
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + PL++AA++++ +V L+E+ A T+ GFT L +A + G+ V L+
Sbjct: 105 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 164
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+G GK + LHIAA+ D A LL+ + ++K G TPLHIAA +
Sbjct: 165 NYGT----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLN 220
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL GA N + G TPLH+A+++G+ M LLL+ G
Sbjct: 221 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Score = 121 bits (292), Expect = 2e-27
Identities = 77/220 (35%), Positives = 110/220 (50%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AAR+ + D LRNG + + LH+AS+ G+V + V LL + T
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIAA +V L+ + A + A ++KGFT L++AA+ +L+V LL +GA +
Sbjct: 79 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 138
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q + V L+ G K LHIAAR + TAA LL+
Sbjct: 139 VATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQ 194
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ SK GFTPLH+AA + + LLL G F
Sbjct: 195 NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF 234
Score = 115 bits (276), Expect = 2e-25
Identities = 57/155 (36%), Positives = 92/155 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
+V+G TP+HLAA+ H +++ +LL A + TPLH+ ++ G+V +A +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T Y PLH+A+ N + L++H A + A TK G++ LH AA+ G+ +
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
LLL +GA+P++ +G TPL IA + +V L
Sbjct: 752 LLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 88.6 bits (210), Expect = 2e-17
Identities = 49/127 (38%), Positives = 68/127 (53%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T+ AA+ GNL A L +G + +NG+ LH+A++ + LL K +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILET 73
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
K G+T LHIAA Q E L+ YGA NA+S+ GFTPL++AAQ+ H E+ LLE
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 673 GPGTQFA 693
G A
Sbjct: 134 GANQNVA 140
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 239 bits (584), Expect = 1e-62
Identities = 114/221 (51%), Positives = 155/221 (70%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ ETP+H+AARA HT++ + LL+N A V AKA++ QTPLH A+R+G+ ++ LLL++ A
Sbjct: 435 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNA 494
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ T + PLHIAA++ + + AL+E A TKKGFT LH+AAKYG ++VA L
Sbjct: 495 NPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAEL 554
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A P+ AGKNG+TPLH+A ++ + LL +G + A NG+TPLHIAA++NQ
Sbjct: 555 LLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 614
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+E A +LL+YG NAES G TPLHLAAQ+GH EM ALLL
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Score = 180 bits (439), Expect = 4e-45
Identities = 93/221 (42%), Positives = 129/221 (58%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H AAR HT+++++LL N A TPLHIA+R G+V+ + LL+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+T + PLH+AAK VA L+E +A A K G T LH+A + NL + LLL
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 590
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G +P NG TPLHIAA+ +Q VA +LL+ G A A + G TPLH+AA++ E
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEM 650
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A N +K+G TPLHL AQ+GH + +L++ G
Sbjct: 651 VALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Score = 176 bits (429), Expect = 6e-44
Identities = 91/222 (40%), Positives = 131/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ ++LL GA+V + TPLHIASR GNV + LLL GA +
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T D PLH AA+ + ++ L++H AP+ A TK G + +H+AA+ +L LLL
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ A D + +TPLH+AA VA LL+KGA + A NG TPLHIA +KN +
Sbjct: 326 QYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVR 385
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA +A +++G TPLH+A+ GH + LL+ G
Sbjct: 386 VMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG 427
Score = 175 bits (425), Expect = 2e-43
Identities = 92/226 (40%), Positives = 130/226 (57%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AAR H I ILL +GA ++AK + +P+H+A++ ++D LLLQ+ A++
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD 333
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT DH PLH+AA +H VA L++ A + GFT LH+A K +++V LLL
Sbjct: 334 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 393
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA+ D ++G+TPLH+A+ + LL++GA TPLH+AAR E A
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA 453
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
LL+ A NA++K TPLH AA+ GHT M LLLE A
Sbjct: 454 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Score = 173 bits (422), Expect = 4e-43
Identities = 88/220 (40%), Positives = 134/220 (60%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A+R + ++R+LL GA +E K ++ TPLH A+R G+V I+ +LL HGA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+A T + +P+H+AA+ + D L++++A + T T LH+AA G+ +VA +LL
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 358
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA P+ NG TPLHIA + + V LL+ GA AV ++G TPLH+A+ +
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLP 418
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA N + TPLH+AA+ GHTE+ LL+
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 458
Score = 173 bits (420), Expect = 7e-43
Identities = 88/225 (39%), Positives = 133/225 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ + +LL A A + TPLH+A N+DI LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + Y PLHIAAKQ+ +VA +L+++ A + +G T LHLAA+ G+ ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 652
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL+ A + K+G+TPLH+ AQ VA L++ G A + G+TPLH+A+
Sbjct: 653 LLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 712
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL++ A NA++K G++PLH AAQQGHT++ LLL+ G
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 757
Score = 165 bits (401), Expect = 1e-40
Identities = 87/224 (38%), Positives = 125/224 (55%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + NH ++ +LL+ GA+++A TPLH+AS +G++ I LLQ GA
Sbjct: 369 LNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
PLH+AA+ + +VA L+++ A + A K T LH AA+ G+ + L
Sbjct: 429 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKL 488
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL + A P+ A G TPLHIAA+ LLEK A + K G TPLH+AA+ +
Sbjct: 489 LLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK 548
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LLE A NA K G TPLH+A + ++ LLL G
Sbjct: 549 VRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Score = 164 bits (398), Expect = 3e-40
Identities = 87/225 (38%), Positives = 129/225 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+A+ H I++ LL+ GA+ + +TPLH+A+R G+ ++A LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLH AA+ + ++ L+E+NA T G T LH+AA+ G+++
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVL 520
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL A+ K G TPLH+AA+Y + VA LLE+ A A KNG TPLH+A N
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL G ++ + G+TPLH+AA+Q E+ LL+ G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYG 625
Score = 162 bits (394), Expect = 1e-39
Identities = 86/223 (38%), Positives = 127/223 (56%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H D +R+LL+ A ++ + TPLH+A+ G+ +A +LL G
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + + PLHIA K+++ V L++ A + A T+ G T LH+A+ G+L +
Sbjct: 362 AKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVK 421
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL GA+P+ + TPLH+AA+ VA LL+ A A AK+ TPLH AAR
Sbjct: 422 NLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG 481
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A N + AG TPLH+AA++GH E LLE
Sbjct: 482 HTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 524
Score = 157 bits (381), Expect = 4e-38
Identities = 84/229 (36%), Positives = 131/229 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+AA A +++R L+ GA V A++++ TPL++A++ ++++ LL++G
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 134
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q + +V A LI + K ALH+AA+ + + A
Sbjct: 135 ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK----GKVRLPALHIAARNDDTRTAA 190
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL + PD K G TPLHIAA Y+ VA LL +GA +NG TPLHIA+R+
Sbjct: 191 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 250
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+ LL+ GA ++K TPLH AA+ GH + +LL+ G Q
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQ 299
Score = 157 bits (380), Expect = 5e-38
Identities = 76/223 (34%), Positives = 124/223 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AAR H + + LL A+ ++ TPLH+A++ G V +A LLL+
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + PLH+A +N D+ L+ + G+T LH+AAK ++VA
Sbjct: 560 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 619
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +G + + G+TPLH+AAQ + LL K A+ K+G TPLH+ A++
Sbjct: 620 SLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ A L+++G + +A ++ G+TPLH+A+ G+ ++ LL+
Sbjct: 680 HVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Score = 155 bits (377), Expect = 1e-37
Identities = 84/218 (38%), Positives = 120/218 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H + ++LL GA ++A TPLHIA + +V + LLL+ GA + A
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T PLH+A+ + + L++ A + K T LH+AA+ G+ +VA LL +
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 459
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + K+ TPLH AA+ + LLE A+ GHTPLHIAAR+ +ET
Sbjct: 460 KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A +K GFTPLH+AA+ G + LLLE
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 153 bits (371), Expect = 6e-37
Identities = 82/229 (35%), Positives = 125/229 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A N+ DI+++LL G + + A TPLHIA++ V++A LLQ+G
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+AA++ + ++ A L+ A K G T LHL A+ G++ VA++L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HG D + G TPLH+A+ Y + LL+ AD A K G++PLH AA++ +
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LL+ GA N S G TPL +A + G+ + +L T F L
Sbjct: 749 IVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVL 797
Score = 151 bits (367), Expect = 2e-36
Identities = 79/218 (36%), Positives = 123/218 (56%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + ++ TPLHIA+ N+++A LLL GA V
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 236
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLHIA+++ N + L++ A + TK T LH AA+ G+++++ +LL HGA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++P+H+AAQ D LL+ A+ + + TPLH+AA A
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKV 356
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA N+ + GFTPLH+A ++ H + LLL+ G
Sbjct: 357 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTG 394
Score = 136 bits (330), Expect = 6e-32
Identities = 77/225 (34%), Positives = 124/225 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H +++ L+ G K + R LHIA+R + A +LLQ+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLLQND 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ ++ + PLHIAA N +VA L+ A + T + G T LH+A++ GN+ +
Sbjct: 197 PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+ +TPLH AA+ ++ LL+ GA +A KNG +P+H+AA+ +
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGD 316
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+Y A + + TPLH+AA GH + +LL+ G
Sbjct: 317 HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 132 bits (318), Expect = 2e-30
Identities = 75/222 (33%), Positives = 120/222 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H ++ LL +E ++ T LHIA+ G ++ L+ +GA+V
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 104
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + PL++AA++++ +V L+E+ A T+ GFT L +A + G+ V L+
Sbjct: 105 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 164
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+G GK + LHIAA+ D A LL+ + ++K G TPLHIAA +
Sbjct: 165 NYGT----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLN 220
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL GA N + G TPLH+A+++G+ M LLL+ G
Sbjct: 221 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Score = 121 bits (292), Expect = 2e-27
Identities = 77/220 (35%), Positives = 110/220 (50%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AAR+ + D LRNG + + LH+AS+ G+V + V LL + T
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIAA +V L+ + A + A ++KGFT L++AA+ +L+V LL +GA +
Sbjct: 79 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 138
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q + V L+ G K LHIAAR + TAA LL+
Sbjct: 139 VATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQ 194
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ SK GFTPLH+AA + + LLL G F
Sbjct: 195 NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF 234
Score = 115 bits (276), Expect = 2e-25
Identities = 57/155 (36%), Positives = 92/155 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
+V+G TP+HLAA+ H +++ +LL A + TPLH+ ++ G+V +A +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T Y PLH+A+ N + L++H A + A TK G++ LH AA+ G+ +
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
LLL +GA+P++ +G TPL IA + +V L
Sbjct: 752 LLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 88.6 bits (210), Expect = 2e-17
Identities = 49/127 (38%), Positives = 68/127 (53%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T+ AA+ GNL A L +G + +NG+ LH+A++ + LL K +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILET 73
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
K G+T LHIAA Q E L+ YGA NA+S+ GFTPL++AAQ+ H E+ LLE
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 673 GPGTQFA 693
G A
Sbjct: 134 GANQNVA 140
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 239 bits (584), Expect = 1e-62
Identities = 114/221 (51%), Positives = 155/221 (70%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ ETP+H+AARA HT++ + LL+N A V AKA++ QTPLH A+R+G+ ++ LLL++ A
Sbjct: 402 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNA 461
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ T + PLHIAA++ + + AL+E A TKKGFT LH+AAKYG ++VA L
Sbjct: 462 NPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAEL 521
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A P+ AGKNG+TPLH+A ++ + LL +G + A NG+TPLHIAA++NQ
Sbjct: 522 LLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 581
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+E A +LL+YG NAES G TPLHLAAQ+GH EM ALLL
Sbjct: 582 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 622
Score = 180 bits (439), Expect = 4e-45
Identities = 93/221 (42%), Positives = 129/221 (58%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H AAR HT+++++LL N A TPLHIA+R G+V+ + LL+ A
Sbjct: 438 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 497
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+T + PLH+AAK VA L+E +A A K G T LH+A + NL + LLL
Sbjct: 498 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 557
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G +P NG TPLHIAA+ +Q VA +LL+ G A A + G TPLH+AA++ E
Sbjct: 558 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEM 617
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A N +K+G TPLHL AQ+GH + +L++ G
Sbjct: 618 VALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 658
Score = 176 bits (429), Expect = 6e-44
Identities = 91/222 (40%), Positives = 131/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ ++LL GA+V + TPLHIASR GNV + LLL GA +
Sbjct: 173 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 232
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T D PLH AA+ + ++ L++H AP+ A TK G + +H+AA+ +L LLL
Sbjct: 233 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 292
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ A D + +TPLH+AA VA LL+KGA + A NG TPLHIA +KN +
Sbjct: 293 QYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVR 352
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA +A +++G TPLH+A+ GH + LL+ G
Sbjct: 353 VMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG 394
Score = 175 bits (425), Expect = 2e-43
Identities = 92/226 (40%), Positives = 130/226 (57%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AAR H I ILL +GA ++AK + +P+H+A++ ++D LLLQ+ A++
Sbjct: 241 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD 300
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT DH PLH+AA +H VA L++ A + GFT LH+A K +++V LLL
Sbjct: 301 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 360
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA+ D ++G+TPLH+A+ + LL++GA TPLH+AAR E A
Sbjct: 361 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA 420
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
LL+ A NA++K TPLH AA+ GHT M LLLE A
Sbjct: 421 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 466
Score = 173 bits (422), Expect = 4e-43
Identities = 88/220 (40%), Positives = 134/220 (60%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A+R + ++R+LL GA +E K ++ TPLH A+R G+V I+ +LL HGA +
Sbjct: 206 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 265
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+A T + +P+H+AA+ + D L++++A + T T LH+AA G+ +VA +LL
Sbjct: 266 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 325
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA P+ NG TPLHIA + + V LL+ GA AV ++G TPLH+A+ +
Sbjct: 326 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLP 385
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA N + TPLH+AA+ GHTE+ LL+
Sbjct: 386 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 425
Score = 173 bits (420), Expect = 7e-43
Identities = 88/225 (39%), Positives = 133/225 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ + +LL A A + TPLH+A N+DI LLL G
Sbjct: 500 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 559
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + Y PLHIAAKQ+ +VA +L+++ A + +G T LHLAA+ G+ ++
Sbjct: 560 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 619
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL+ A + K+G+TPLH+ AQ VA L++ G A + G+TPLH+A+
Sbjct: 620 LLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 679
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL++ A NA++K G++PLH AAQQGHT++ LLL+ G
Sbjct: 680 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 724
Score = 165 bits (401), Expect = 1e-40
Identities = 87/224 (38%), Positives = 125/224 (55%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + NH ++ +LL+ GA+++A TPLH+AS +G++ I LLQ GA
Sbjct: 336 LNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 395
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
PLH+AA+ + +VA L+++ A + A K T LH AA+ G+ + L
Sbjct: 396 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKL 455
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL + A P+ A G TPLHIAA+ LLEK A + K G TPLH+AA+ +
Sbjct: 456 LLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK 515
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LLE A NA K G TPLH+A + ++ LLL G
Sbjct: 516 VRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 559
Score = 164 bits (398), Expect = 3e-40
Identities = 87/225 (38%), Positives = 129/225 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+A+ H I++ LL+ GA+ + +TPLH+A+R G+ ++A LLQ+
Sbjct: 368 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 427
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLH AA+ + ++ L+E+NA T G T LH+AA+ G+++
Sbjct: 428 AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVL 487
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL A+ K G TPLH+AA+Y + VA LLE+ A A KNG TPLH+A N
Sbjct: 488 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 547
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL G ++ + G+TPLH+AA+Q E+ LL+ G
Sbjct: 548 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYG 592
Score = 162 bits (394), Expect = 1e-39
Identities = 86/223 (38%), Positives = 127/223 (56%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H D +R+LL+ A ++ + TPLH+A+ G+ +A +LL G
Sbjct: 269 TKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 328
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + + PLHIA K+++ V L++ A + A T+ G T LH+A+ G+L +
Sbjct: 329 AKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVK 388
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL GA+P+ + TPLH+AA+ VA LL+ A A AK+ TPLH AAR
Sbjct: 389 NLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG 448
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A N + AG TPLH+AA++GH E LLE
Sbjct: 449 HTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 491
Score = 157 bits (380), Expect = 5e-38
Identities = 76/223 (34%), Positives = 124/223 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AAR H + + LL A+ ++ TPLH+A++ G V +A LLL+
Sbjct: 467 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 526
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + PLH+A +N D+ L+ + G+T LH+AAK ++VA
Sbjct: 527 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 586
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +G + + G+TPLH+AAQ + LL K A+ K+G TPLH+ A++
Sbjct: 587 SLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 646
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ A L+++G + +A ++ G+TPLH+A+ G+ ++ LL+
Sbjct: 647 HVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 689
Score = 156 bits (378), Expect = 9e-38
Identities = 83/227 (36%), Positives = 130/227 (57%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G T +H+AA A +++R L+ GA V A++++ TPL++A++ ++++ LL++GA+
Sbjct: 44 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 103
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T D + PL +A +Q + +V A LI + K ALH+AA+ + + A +L
Sbjct: 104 QNVATEDGFTPLAVALQQGHENVVAHLINYGTK----GKVRLPALHIAARNDDTRTAAVL 159
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + PD K G TPLHIAA Y+ VA LL +GA +NG TPLHIA+R+ +
Sbjct: 160 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNV 219
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ GA ++K TPLH AA+ GH + +LL+ G Q
Sbjct: 220 IMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQ 266
Score = 155 bits (377), Expect = 1e-37
Identities = 84/218 (38%), Positives = 120/218 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H + ++LL GA ++A TPLHIA + +V + LLL+ GA + A
Sbjct: 307 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 366
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T PLH+A+ + + L++ A + K T LH+AA+ G+ +VA LL +
Sbjct: 367 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 426
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + K+ TPLH AA+ + LLE A+ GHTPLHIAAR+ +ET
Sbjct: 427 KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETV 486
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A +K GFTPLH+AA+ G + LLLE
Sbjct: 487 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 524
Score = 153 bits (371), Expect = 6e-37
Identities = 82/229 (35%), Positives = 125/229 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A N+ DI+++LL G + + A TPLHIA++ V++A LLQ+G
Sbjct: 536 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 595
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+AA++ + ++ A L+ A K G T LHL A+ G++ VA++L+
Sbjct: 596 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 655
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HG D + G TPLH+A+ Y + LL+ AD A K G++PLH AA++ +
Sbjct: 656 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 715
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LL+ GA N S G TPL +A + G+ + +L T F L
Sbjct: 716 IVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVL 764
Score = 151 bits (367), Expect = 2e-36
Identities = 79/218 (36%), Positives = 123/218 (56%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + ++ TPLHIA+ N+++A LLL GA V
Sbjct: 144 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 203
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLHIA+++ N + L++ A + TK T LH AA+ G+++++ +LL HGA
Sbjct: 204 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 263
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++P+H+AAQ D LL+ A+ + + TPLH+AA A
Sbjct: 264 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKV 323
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA N+ + GFTPLH+A ++ H + LLL+ G
Sbjct: 324 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTG 361
Score = 136 bits (330), Expect = 6e-32
Identities = 77/225 (34%), Positives = 124/225 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H +++ L+ G K + R LHIA+R + A +LLQ+
Sbjct: 108 TEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLLQND 163
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ ++ + PLHIAA N +VA L+ A + T + G T LH+A++ GN+ +
Sbjct: 164 PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVR 223
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+ +TPLH AA+ ++ LL+ GA +A KNG +P+H+AA+ +
Sbjct: 224 LLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGD 283
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+Y A + + TPLH+AA GH + +LL+ G
Sbjct: 284 HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 328
Score = 128 bits (308), Expect = 3e-29
Identities = 75/215 (34%), Positives = 117/215 (54%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AAR+ + D LRNG + ++ T LHIA+ G ++ L+ +GA+V A +
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 78
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
+ PL++AA++++ +V L+E+ A T+ GFT L +A + G+ V L+ +G
Sbjct: 79 FTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGT--- 135
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
GK + LHIAA+ D A LL+ + ++K G TPLHIAA + A LL
Sbjct: 136 -KGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 194
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA N + G TPLH+A+++G+ M LLL+ G
Sbjct: 195 RGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 229
Score = 115 bits (276), Expect = 2e-25
Identities = 57/155 (36%), Positives = 92/155 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
+V+G TP+HLAA+ H +++ +LL A + TPLH+ ++ G+V +A +L++HG
Sbjct: 599 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 658
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T Y PLH+A+ N + L++H A + A TK G++ LH AA+ G+ +
Sbjct: 659 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 718
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
LLL +GA+P++ +G TPL IA + +V L
Sbjct: 719 LLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 753
Score = 114 bits (275), Expect = 3e-25
Identities = 68/187 (36%), Positives = 98/187 (52%)
Frame = +1
Query: 130 ASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG 309
A+R GN+D A+ L++G D+ LHIAA +V L+ + A + A ++KG
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 78
Query: 310 FTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAK 489
FT L++AA+ +L+V LL +GA + A ++G TPL +A Q + V L+ G K
Sbjct: 79 FTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGK 138
Query: 490 AVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LHIAAR + TAA LL+ + SK GFTPLH+AA + + LLL
Sbjct: 139 VRL----PALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 194
Query: 670 GGPGTQF 690
G F
Sbjct: 195 RGASVNF 201
Score = 85.4 bits (202), Expect = 2e-16
Identities = 49/121 (40%), Positives = 68/121 (56%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T+ AA+ GNL A L +G + + G T LHIAA Q V L+ GA+ A
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNA 73
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
++ G TPL++AA++N +E LLE GA N ++ GFTPL +A QQGH + A L+
Sbjct: 74 QSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 133
Query: 673 G 675
G
Sbjct: 134 G 134
Score = 69.7 bits (163), Expect = 1e-11
Identities = 34/76 (44%), Positives = 43/76 (56%)
Frame = +1
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L G D + G+T LHIAA Q E L+ YGA NA+S+ GFTPL++AAQ+ H
Sbjct: 32 LRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHL 91
Query: 646 EMCALLLEGGPGTQFA 693
E+ LLE G A
Sbjct: 92 EVVKFLLENGANQNVA 107
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 239 bits (584), Expect = 1e-62
Identities = 114/221 (51%), Positives = 155/221 (70%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ ETP+H+AARA HT++ + LL+N A V AKA++ QTPLH A+R+G+ ++ LLL++ A
Sbjct: 435 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNA 494
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ T + PLHIAA++ + + AL+E A TKKGFT LH+AAKYG ++VA L
Sbjct: 495 NPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAEL 554
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A P+ AGKNG+TPLH+A ++ + LL +G + A NG+TPLHIAA++NQ
Sbjct: 555 LLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 614
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+E A +LL+YG NAES G TPLHLAAQ+GH EM ALLL
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Score = 180 bits (439), Expect = 4e-45
Identities = 93/221 (42%), Positives = 129/221 (58%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H AAR HT+++++LL N A TPLHIA+R G+V+ + LL+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+T + PLH+AAK VA L+E +A A K G T LH+A + NL + LLL
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 590
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G +P NG TPLHIAA+ +Q VA +LL+ G A A + G TPLH+AA++ E
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEM 650
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A N +K+G TPLHL AQ+GH + +L++ G
Sbjct: 651 VALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Score = 175 bits (426), Expect = 1e-43
Identities = 90/222 (40%), Positives = 131/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ ++LL G++V + TPLHIASR GNV + LLL GA +
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T D PLH AA+ + ++ L++H AP+ A TK G + +H+AA+ +L LLL
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ A D + +TPLH+AA VA LL+KGA + A NG TPLHIA +KN +
Sbjct: 326 QYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVR 385
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA +A +++G TPLH+A+ GH + LL+ G
Sbjct: 386 VMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG 427
Score = 175 bits (425), Expect = 2e-43
Identities = 92/226 (40%), Positives = 130/226 (57%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AAR H I ILL +GA ++AK + +P+H+A++ ++D LLLQ+ A++
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD 333
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT DH PLH+AA +H VA L++ A + GFT LH+A K +++V LLL
Sbjct: 334 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 393
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA+ D ++G+TPLH+A+ + LL++GA TPLH+AAR E A
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA 453
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
LL+ A NA++K TPLH AA+ GHT M LLLE A
Sbjct: 454 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Score = 173 bits (422), Expect = 4e-43
Identities = 88/220 (40%), Positives = 134/220 (60%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A+R + ++R+LL GA +E K ++ TPLH A+R G+V I+ +LL HGA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+A T + +P+H+AA+ + D L++++A + T T LH+AA G+ +VA +LL
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 358
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA P+ NG TPLHIA + + V LL+ GA AV ++G TPLH+A+ +
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLP 418
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA N + TPLH+AA+ GHTE+ LL+
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 458
Score = 173 bits (420), Expect = 7e-43
Identities = 88/225 (39%), Positives = 133/225 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ + +LL A A + TPLH+A N+DI LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + Y PLHIAAKQ+ +VA +L+++ A + +G T LHLAA+ G+ ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 652
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL+ A + K+G+TPLH+ AQ VA L++ G A + G+TPLH+A+
Sbjct: 653 LLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 712
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL++ A NA++K G++PLH AAQQGHT++ LLL+ G
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 757
Score = 165 bits (401), Expect = 1e-40
Identities = 87/224 (38%), Positives = 125/224 (55%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + NH ++ +LL+ GA+++A TPLH+AS +G++ I LLQ GA
Sbjct: 369 LNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 428
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
PLH+AA+ + +VA L+++ A + A K T LH AA+ G+ + L
Sbjct: 429 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKL 488
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL + A P+ A G TPLHIAA+ LLEK A + K G TPLH+AA+ +
Sbjct: 489 LLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK 548
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LLE A NA K G TPLH+A + ++ LLL G
Sbjct: 549 VRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Score = 164 bits (398), Expect = 3e-40
Identities = 87/225 (38%), Positives = 129/225 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+A+ H I++ LL+ GA+ + +TPLH+A+R G+ ++A LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLH AA+ + ++ L+E+NA T G T LH+AA+ G+++
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVL 520
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL A+ K G TPLH+AA+Y + VA LLE+ A A KNG TPLH+A N
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL G ++ + G+TPLH+AA+Q E+ LL+ G
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYG 625
Score = 162 bits (394), Expect = 1e-39
Identities = 86/223 (38%), Positives = 127/223 (56%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H D +R+LL+ A ++ + TPLH+A+ G+ +A +LL G
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + + PLHIA K+++ V L++ A + A T+ G T LH+A+ G+L +
Sbjct: 362 AKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVK 421
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL GA+P+ + TPLH+AA+ VA LL+ A A AK+ TPLH AAR
Sbjct: 422 NLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG 481
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A N + AG TPLH+AA++GH E LLE
Sbjct: 482 HTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 524
Score = 157 bits (380), Expect = 5e-38
Identities = 76/223 (34%), Positives = 124/223 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AAR H + + LL A+ ++ TPLH+A++ G V +A LLL+
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + PLH+A +N D+ L+ + G+T LH+AAK ++VA
Sbjct: 560 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 619
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +G + + G+TPLH+AAQ + LL K A+ K+G TPLH+ A++
Sbjct: 620 SLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 679
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ A L+++G + +A ++ G+TPLH+A+ G+ ++ LL+
Sbjct: 680 HVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Score = 156 bits (378), Expect = 9e-38
Identities = 83/229 (36%), Positives = 131/229 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+AA A +++R L+ GA V A++++ TPL++A++ ++++ LL++G
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 134
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q + +V A LI + K ALH+AA+ + + A
Sbjct: 135 ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK----GKVRLPALHIAARNDDTRTAA 190
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL + PD K G TPLHIAA Y+ VA LL +G+ +NG TPLHIA+R+
Sbjct: 191 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRG 250
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+ LL+ GA ++K TPLH AA+ GH + +LL+ G Q
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQ 299
Score = 155 bits (377), Expect = 1e-37
Identities = 84/218 (38%), Positives = 120/218 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H + ++LL GA ++A TPLHIA + +V + LLL+ GA + A
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T PLH+A+ + + L++ A + K T LH+AA+ G+ +VA LL +
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 459
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + K+ TPLH AA+ + LLE A+ GHTPLHIAAR+ +ET
Sbjct: 460 KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A +K GFTPLH+AA+ G + LLLE
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 153 bits (371), Expect = 6e-37
Identities = 82/229 (35%), Positives = 125/229 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A N+ DI+++LL G + + A TPLHIA++ V++A LLQ+G
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+AA++ + ++ A L+ A K G T LHL A+ G++ VA++L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HG D + G TPLH+A+ Y + LL+ AD A K G++PLH AA++ +
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LL+ GA N S G TPL +A + G+ + +L T F L
Sbjct: 749 IVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVL 797
Score = 150 bits (364), Expect = 4e-36
Identities = 78/218 (35%), Positives = 123/218 (56%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + ++ TPLHIA+ N+++A LLL G+ V
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTP 236
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLHIA+++ N + L++ A + TK T LH AA+ G+++++ +LL HGA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++P+H+AAQ D LL+ A+ + + TPLH+AA A
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKV 356
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA N+ + GFTPLH+A ++ H + LLL+ G
Sbjct: 357 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTG 394
Score = 135 bits (327), Expect = 1e-31
Identities = 76/225 (33%), Positives = 124/225 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H +++ L+ G K + R LHIA+R + A +LLQ+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLLQND 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ ++ + PLHIAA N +VA L+ + + T + G T LH+A++ GN+ +
Sbjct: 197 PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+ +TPLH AA+ ++ LL+ GA +A KNG +P+H+AA+ +
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGD 316
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+Y A + + TPLH+AA GH + +LL+ G
Sbjct: 317 HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 130 bits (315), Expect = 4e-30
Identities = 74/222 (33%), Positives = 120/222 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H ++ LL +E ++ T LHIA+ G ++ L+ +GA+V
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 104
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + PL++AA++++ +V L+E+ A T+ GFT L +A + G+ V L+
Sbjct: 105 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 164
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+G GK + LHIAA+ D A LL+ + ++K G TPLHIAA +
Sbjct: 165 NYGT----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLN 220
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL G+ N + G TPLH+A+++G+ M LLL+ G
Sbjct: 221 VAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Score = 121 bits (292), Expect = 2e-27
Identities = 77/220 (35%), Positives = 110/220 (50%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AAR+ + D LRNG + + LH+AS+ G+V + V LL + T
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIAA +V L+ + A + A ++KGFT L++AA+ +L+V LL +GA +
Sbjct: 79 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 138
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q + V L+ G K LHIAAR + TAA LL+
Sbjct: 139 VATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQ 194
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ SK GFTPLH+AA + + LLL G F
Sbjct: 195 NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNF 234
Score = 115 bits (276), Expect = 2e-25
Identities = 57/155 (36%), Positives = 92/155 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
+V+G TP+HLAA+ H +++ +LL A + TPLH+ ++ G+V +A +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T Y PLH+A+ N + L++H A + A TK G++ LH AA+ G+ +
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
LLL +GA+P++ +G TPL IA + +V L
Sbjct: 752 LLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 88.6 bits (210), Expect = 2e-17
Identities = 49/127 (38%), Positives = 68/127 (53%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T+ AA+ GNL A L +G + +NG+ LH+A++ + LL K +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILET 73
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
K G+T LHIAA Q E L+ YGA NA+S+ GFTPL++AAQ+ H E+ LLE
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 673 GPGTQFA 693
G A
Sbjct: 134 GANQNVA 140
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 variant
protein.
Length = 1899
Score = 239 bits (584), Expect = 1e-62
Identities = 114/221 (51%), Positives = 155/221 (70%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ ETP+H+AARA HT++ + LL+N A V AKA++ QTPLH A+R+G+ ++ LLL++ A
Sbjct: 470 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNA 529
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ T + PLHIAA++ + + AL+E A TKKGFT LH+AAKYG ++VA L
Sbjct: 530 NPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAEL 589
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL A P+ AGKNG+TPLH+A ++ + LL +G + A NG+TPLHIAA++NQ
Sbjct: 590 LLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 649
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+E A +LL+YG NAES G TPLHLAAQ+GH EM ALLL
Sbjct: 650 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 690
Score = 180 bits (439), Expect = 4e-45
Identities = 93/221 (42%), Positives = 129/221 (58%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H AAR HT+++++LL N A TPLHIA+R G+V+ + LL+ A
Sbjct: 506 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 565
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+T + PLH+AAK VA L+E +A A K G T LH+A + NL + LLL
Sbjct: 566 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 625
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G +P NG TPLHIAA+ +Q VA +LL+ G A A + G TPLH+AA++ E
Sbjct: 626 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEM 685
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL A N +K+G TPLHL AQ+GH + +L++ G
Sbjct: 686 VALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 726
Score = 176 bits (429), Expect = 6e-44
Identities = 91/222 (40%), Positives = 131/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA + ++ ++LL GA+V + TPLHIASR GNV + LLL GA +
Sbjct: 241 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 300
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
T D PLH AA+ + ++ L++H AP+ A TK G + +H+AA+ +L LLL
Sbjct: 301 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 360
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ A D + +TPLH+AA VA LL+KGA + A NG TPLHIA +KN +
Sbjct: 361 QYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVR 420
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA +A +++G TPLH+A+ GH + LL+ G
Sbjct: 421 VMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG 462
Score = 175 bits (425), Expect = 2e-43
Identities = 92/226 (40%), Positives = 130/226 (57%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AAR H I ILL +GA ++AK + +P+H+A++ ++D LLLQ+ A++
Sbjct: 309 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD 368
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT DH PLH+AA +H VA L++ A + GFT LH+A K +++V LLL
Sbjct: 369 ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 428
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA+ D ++G+TPLH+A+ + LL++GA TPLH+AAR E A
Sbjct: 429 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA 488
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
LL+ A NA++K TPLH AA+ GHT M LLLE A
Sbjct: 489 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 534
Score = 173 bits (422), Expect = 4e-43
Identities = 88/220 (40%), Positives = 134/220 (60%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A+R + ++R+LL GA +E K ++ TPLH A+R G+V I+ +LL HGA +
Sbjct: 274 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 333
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+A T + +P+H+AA+ + D L++++A + T T LH+AA G+ +VA +LL
Sbjct: 334 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 393
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA P+ NG TPLHIA + + V LL+ GA AV ++G TPLH+A+ +
Sbjct: 394 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLP 453
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LL+ GA N + TPLH+AA+ GHTE+ LL+
Sbjct: 454 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQ 493
Score = 173 bits (420), Expect = 7e-43
Identities = 88/225 (39%), Positives = 133/225 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+H+AA+ + +LL A A + TPLH+A N+DI LLL G
Sbjct: 568 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 627
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + Y PLHIAAKQ+ +VA +L+++ A + +G T LHLAA+ G+ ++
Sbjct: 628 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 687
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL+ A + K+G+TPLH+ AQ VA L++ G A + G+TPLH+A+
Sbjct: 688 LLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 747
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL++ A NA++K G++PLH AAQQGHT++ LLL+ G
Sbjct: 748 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 792
Score = 165 bits (401), Expect = 1e-40
Identities = 87/224 (38%), Positives = 125/224 (55%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+H+A + NH ++ +LL+ GA+++A TPLH+AS +G++ I LLQ GA
Sbjct: 404 LNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 463
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
PLH+AA+ + +VA L+++ A + A K T LH AA+ G+ + L
Sbjct: 464 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKL 523
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL + A P+ A G TPLHIAA+ LLEK A + K G TPLH+AA+ +
Sbjct: 524 LLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK 583
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A LLE A NA K G TPLH+A + ++ LLL G
Sbjct: 584 VRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 627
Score = 164 bits (398), Expect = 3e-40
Identities = 87/225 (38%), Positives = 129/225 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+A+ H I++ LL+ GA+ + +TPLH+A+R G+ ++A LLQ+
Sbjct: 436 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 495
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A D PLH AA+ + ++ L+E+NA T G T LH+AA+ G+++
Sbjct: 496 AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVL 555
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL A+ K G TPLH+AA+Y + VA LLE+ A A KNG TPLH+A N
Sbjct: 556 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 615
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL G ++ + G+TPLH+AA+Q E+ LL+ G
Sbjct: 616 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYG 660
Score = 162 bits (394), Expect = 1e-39
Identities = 86/223 (38%), Positives = 127/223 (56%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +P+H+AA+ +H D +R+LL+ A ++ + TPLH+A+ G+ +A +LL G
Sbjct: 337 TKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 396
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A + + + PLHIA K+++ V L++ A + A T+ G T LH+A+ G+L +
Sbjct: 397 AKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVK 456
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL GA+P+ + TPLH+AA+ VA LL+ A A AK+ TPLH AAR
Sbjct: 457 NLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG 516
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A N + AG TPLH+AA++GH E LLE
Sbjct: 517 HTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLE 559
Score = 157 bits (381), Expect = 4e-38
Identities = 84/229 (36%), Positives = 131/229 (57%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G T +H+AA A +++R L+ GA V A++++ TPL++A++ ++++ LL++G
Sbjct: 110 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 169
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+ T D + PL +A +Q + +V A LI + K ALH+AA+ + + A
Sbjct: 170 ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK----GKVRLPALHIAARNDDTRTAA 225
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL + PD K G TPLHIAA Y+ VA LL +GA +NG TPLHIA+R+
Sbjct: 226 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 285
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
+ LL+ GA ++K TPLH AA+ GH + +LL+ G Q
Sbjct: 286 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQ 334
Score = 157 bits (380), Expect = 5e-38
Identities = 76/223 (34%), Positives = 124/223 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+H+AAR H + + LL A+ ++ TPLH+A++ G V +A LLL+
Sbjct: 535 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 594
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A + PLH+A +N D+ L+ + G+T LH+AAK ++VA
Sbjct: 595 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 654
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL +G + + G+TPLH+AAQ + LL K A+ K+G TPLH+ A++
Sbjct: 655 SLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEG 714
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ A L+++G + +A ++ G+TPLH+A+ G+ ++ LL+
Sbjct: 715 HVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 757
Score = 155 bits (377), Expect = 1e-37
Identities = 84/218 (38%), Positives = 120/218 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H + ++LL GA ++A TPLHIA + +V + LLL+ GA + A
Sbjct: 375 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 434
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+T PLH+A+ + + L++ A + K T LH+AA+ G+ +VA LL +
Sbjct: 435 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 494
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + K+ TPLH AA+ + LLE A+ GHTPLHIAAR+ +ET
Sbjct: 495 KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETV 554
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
LLE A +K GFTPLH+AA+ G + LLLE
Sbjct: 555 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 592
Score = 153 bits (371), Expect = 6e-37
Identities = 82/229 (35%), Positives = 125/229 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+A N+ DI+++LL G + + A TPLHIA++ V++A LLQ+G
Sbjct: 604 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 663
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+AA++ + ++ A L+ A K G T LHL A+ G++ VA++L+
Sbjct: 664 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 723
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HG D + G TPLH+A+ Y + LL+ AD A K G++PLH AA++ +
Sbjct: 724 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 783
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LL+ GA N S G TPL +A + G+ + +L T F L
Sbjct: 784 IVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVL 832
Score = 151 bits (367), Expect = 2e-36
Identities = 79/218 (36%), Positives = 123/218 (56%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR + T +LL+N + ++ TPLHIA+ N+++A LLL GA V
Sbjct: 212 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 271
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PLHIA+++ N + L++ A + TK T LH AA+ G+++++ +LL HGA
Sbjct: 272 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 331
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
KNG++P+H+AAQ D LL+ A+ + + TPLH+AA A
Sbjct: 332 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKV 391
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA N+ + GFTPLH+A ++ H + LLL+ G
Sbjct: 392 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTG 429
Score = 136 bits (330), Expect = 6e-32
Identities = 77/225 (34%), Positives = 124/225 (55%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +A + H +++ L+ G K + R LHIA+R + A +LLQ+
Sbjct: 176 TEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLLQND 231
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ ++ + PLHIAA N +VA L+ A + T + G T LH+A++ GN+ +
Sbjct: 232 PNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVR 291
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA + K+ +TPLH AA+ ++ LL+ GA +A KNG +P+H+AA+ +
Sbjct: 292 LLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGD 351
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ LL+Y A + + TPLH+AA GH + +LL+ G
Sbjct: 352 HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 396
Score = 132 bits (318), Expect = 2e-30
Identities = 75/222 (33%), Positives = 120/222 (54%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +HLA++ H ++ LL +E ++ T LHIA+ G ++ L+ +GA+V
Sbjct: 80 GLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 139
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + + PL++AA++++ +V L+E+ A T+ GFT L +A + G+ V L+
Sbjct: 140 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 199
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+G GK + LHIAA+ D A LL+ + ++K G TPLHIAA +
Sbjct: 200 NYGT----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLN 255
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A LL GA N + G TPLH+A+++G+ M LLL+ G
Sbjct: 256 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 297
Score = 121 bits (292), Expect = 2e-27
Identities = 77/220 (35%), Positives = 110/220 (50%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
AAR+ + D LRNG + + LH+AS+ G+V + V LL + T
Sbjct: 54 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 113
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
LHIAA +V L+ + A + A ++KGFT L++AA+ +L+V LL +GA +
Sbjct: 114 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 173
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
A ++G TPL +A Q + V L+ G K LHIAAR + TAA LL+
Sbjct: 174 VATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQ 229
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
+ SK GFTPLH+AA + + LLL G F
Sbjct: 230 NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF 269
Score = 115 bits (276), Expect = 2e-25
Identities = 68/202 (33%), Positives = 104/202 (51%)
Frame = +1
Query: 73 RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHD 252
RN + K + T A+R GN+D A+ L++G D+ + N LH+A+K+ +
Sbjct: 35 RNRSRDRKKKADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVK 94
Query: 253 VAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
+ L+ L TTKKG TALH+AA G +V L+ +GA + + G TPL++AA
Sbjct: 95 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAA 154
Query: 433 QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
Q + V LLE GA+ ++G TPL +A ++ A L+ YG + K
Sbjct: 155 QENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKVRLP 210
Query: 613 PLHLAAQQGHTEMCALLLEGGP 678
LH+AA+ T A+LL+ P
Sbjct: 211 ALHIAARNDDTRTAAVLLQNDP 232
Score = 115 bits (276), Expect = 2e-25
Identities = 57/155 (36%), Positives = 92/155 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
+V+G TP+HLAA+ H +++ +LL A + TPLH+ ++ G+V +A +L++HG
Sbjct: 667 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 726
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T Y PLH+A+ N + L++H A + A TK G++ LH AA+ G+ +
Sbjct: 727 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 786
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
LLL +GA+P++ +G TPL IA + +V L
Sbjct: 787 LLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 821
Score = 88.6 bits (210), Expect = 2e-17
Identities = 49/127 (38%), Positives = 68/127 (53%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T+ AA+ GNL A L +G + +NG+ LH+A++ + LL K +
Sbjct: 49 TSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILET 108
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
K G+T LHIAA Q E L+ YGA NA+S+ GFTPL++AAQ+ H E+ LLE
Sbjct: 109 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 168
Query: 673 GPGTQFA 693
G A
Sbjct: 169 GANQNVA 175
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 167 bits (405), Expect = 5e-41
Identities = 85/222 (38%), Positives = 133/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+AA H ++++L GA ++A+ R +TPLH+A G V LL+ GA
Sbjct: 494 GKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVP 553
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ Y PLH AA + + + L+ + A L T +G+T LHLAA G+L++ +LL
Sbjct: 554 DALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLA 613
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G TPLH+AA++ ++AV + LL+ GAD A ++G TPLH+A +++
Sbjct: 614 ESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFL 673
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LLE+ A +A +K G+TP HLAA +G+T + +L+E G
Sbjct: 674 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715
Score = 147 bits (355), Expect = 5e-35
Identities = 77/220 (35%), Positives = 121/220 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H + +R+LL + V+ + TPL IA++ D+ LLL HGAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D + PLH AA+ + A L++H A + A ++G+T LHLAA+ VA LL++
Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSR 483
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A P+ G TPLH+AA + ++ L +GA+ A +N TPLH+A + ++
Sbjct: 484 QADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAI 543
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA+ +A ++G+ PLH AA +G +C +LL G
Sbjct: 544 QHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYG 583
Score = 145 bits (352), Expect = 1e-34
Identities = 82/223 (36%), Positives = 121/223 (54%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +AA+ D+ +LL +GA + PLH A++ G+ A LLL HG
Sbjct: 392 TASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHG 451
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A + + PLH+AA+ + +VA L+ A +G T LH+AA +G++ +
Sbjct: 452 ACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVK 511
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL + GA D +N TPLH+A + + LL+ GA A+ ++G+ PLH AA +
Sbjct: 512 LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARG 571
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL YGA + G+TPLHLAA +GH E+ LL E
Sbjct: 572 KYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAE 614
Score = 134 bits (323), Expect = 4e-31
Identities = 80/222 (36%), Positives = 112/222 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA+ R+LL +GA V+A+ RE TPLH+A++ ++A LL+ AD
Sbjct: 428 GWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADP 487
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ PLH+AA + + L A L A + T LHLA + G ++ LL
Sbjct: 488 NLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLL 547
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA PD ++G PLH AA + + LL GA + G TPLH+AA K +E
Sbjct: 548 KSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLE 607
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L E A A +TPLHLAA+ G + + LL+ G
Sbjct: 608 IIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649
Score = 131 bits (316), Expect = 3e-30
Identities = 73/209 (34%), Positives = 111/209 (53%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+HLAA+ N ++ R+L+ A E +TPLH+A+ G+V + LL GA++
Sbjct: 461 GWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAEL 520
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+A ++ L++ A A + G+ LH AA G + +LL
Sbjct: 521 DAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLL 580
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA+ + G TPLH+AA + L E A+ A+ TPLH+AAR +
Sbjct: 581 RYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEA 640
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
+ LL+ GA NA ++G+TPLHLA Q+
Sbjct: 641 VVSALLQCGADPNAAEQSGWTPLHLAVQR 669
Score = 124 bits (298), Expect = 4e-28
Identities = 74/204 (36%), Positives = 106/204 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+HLA I+ LL++GA +A + PLH A+ G I +LL++GA +
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+AA + + ++ L E +A + A +T LHLAA++G V + LL
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQC 648
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA P+ A ++G TPLH+A Q LLE A+ A K G TP H+AA K
Sbjct: 649 GADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAIL 708
Query: 556 ATLLEYGALTNAESKAGFTPLHLA 627
L+E GA + + TPL LA
Sbjct: 709 KVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 102 bits (244), Expect = 2e-21
Identities = 64/179 (35%), Positives = 94/179 (52%), Gaps = 1/179 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA I ++LLR GA++E + TPLH+A+ G+++I LL + A++
Sbjct: 560 GYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANM 619
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN-LKVANLL 366
A+ A ++ PLH+AA+ V +AL++ A A + G+T LHLA + L V NLL
Sbjct: 620 GALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLL 679
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
H A K G TP H+AA A+ L+E GA TPL +A R +
Sbjct: 680 -EHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRK 737
Score = 97.9 bits (233), Expect = 3e-20
Identities = 59/172 (34%), Positives = 86/172 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+HLAA H +II +L + A + A TPLH+A+R G + LLQ G
Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A + PLH+A ++ L+EH+A + A K G+T HLAA GN +
Sbjct: 650 ADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILK 709
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
+L+ GA D TPL +A + +Q + + L +G + G P
Sbjct: 710 VLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL--EGKEPSVATLGGSKP 759
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/92 (36%), Positives = 44/92 (47%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
+N +TPLH LL D +G+TPL IAA+ Q + A LL +GA
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA 419
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N + G+ PLH AAQ G LLL+ G
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHG 451
Score = 45.2 bits (102), Expect = 2e-04
Identities = 21/61 (34%), Positives = 34/61 (55%)
Frame = +1
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+ +N TPLH + +E LL + + ++ +G+TPL +AAQ ++CALLL
Sbjct: 358 IYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAH 417
Query: 673 G 675
G
Sbjct: 418 G 418
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 167 bits (405), Expect = 5e-41
Identities = 85/222 (38%), Positives = 133/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+AA H ++++L GA ++A+ R +TPLH+A G V LL+ GA
Sbjct: 494 GKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVP 553
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ Y PLH AA + + + L+ + A L T +G+T LHLAA G+L++ +LL
Sbjct: 554 DALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLA 613
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G TPLH+AA++ ++AV + LL+ GAD A ++G TPLH+A +++
Sbjct: 614 ESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFL 673
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LLE+ A +A +K G+TP HLAA +G+T + +L+E G
Sbjct: 674 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715
Score = 147 bits (355), Expect = 5e-35
Identities = 77/220 (35%), Positives = 121/220 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H + +R+LL + V+ + TPL IA++ D+ LLL HGAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D + PLH AA+ + A L++H A + A ++G+T LHLAA+ VA LL++
Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSR 483
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A P+ G TPLH+AA + ++ L +GA+ A +N TPLH+A + ++
Sbjct: 484 QADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAI 543
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA+ +A ++G+ PLH AA +G +C +LL G
Sbjct: 544 QHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYG 583
Score = 145 bits (352), Expect = 1e-34
Identities = 82/223 (36%), Positives = 121/223 (54%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +AA+ D+ +LL +GA + PLH A++ G+ A LLL HG
Sbjct: 392 TASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHG 451
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A + + PLH+AA+ + +VA L+ A +G T LH+AA +G++ +
Sbjct: 452 ACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVK 511
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL + GA D +N TPLH+A + + LL+ GA A+ ++G+ PLH AA +
Sbjct: 512 LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARG 571
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL YGA + G+TPLHLAA +GH E+ LL E
Sbjct: 572 KYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAE 614
Score = 134 bits (323), Expect = 4e-31
Identities = 80/222 (36%), Positives = 112/222 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA+ R+LL +GA V+A+ RE TPLH+A++ ++A LL+ AD
Sbjct: 428 GWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADP 487
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ PLH+AA + + L A L A + T LHLA + G ++ LL
Sbjct: 488 NLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLL 547
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA PD ++G PLH AA + + LL GA + G TPLH+AA K +E
Sbjct: 548 KSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLE 607
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L E A A +TPLHLAA+ G + + LL+ G
Sbjct: 608 IIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649
Score = 131 bits (316), Expect = 3e-30
Identities = 73/209 (34%), Positives = 111/209 (53%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+HLAA+ N ++ R+L+ A E +TPLH+A+ G+V + LL GA++
Sbjct: 461 GWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAEL 520
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+A ++ L++ A A + G+ LH AA G + +LL
Sbjct: 521 DAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLL 580
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA+ + G TPLH+AA + L E A+ A+ TPLH+AAR +
Sbjct: 581 RYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEA 640
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
+ LL+ GA NA ++G+TPLHLA Q+
Sbjct: 641 VVSALLQCGADPNAAEQSGWTPLHLAVQR 669
Score = 124 bits (298), Expect = 4e-28
Identities = 74/204 (36%), Positives = 106/204 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+HLA I+ LL++GA +A + PLH A+ G I +LL++GA +
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+AA + + ++ L E +A + A +T LHLAA++G V + LL
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQC 648
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA P+ A ++G TPLH+A Q LLE A+ A K G TP H+AA K
Sbjct: 649 GADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAIL 708
Query: 556 ATLLEYGALTNAESKAGFTPLHLA 627
L+E GA + + TPL LA
Sbjct: 709 KVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 102 bits (244), Expect = 2e-21
Identities = 64/179 (35%), Positives = 94/179 (52%), Gaps = 1/179 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA I ++LLR GA++E + TPLH+A+ G+++I LL + A++
Sbjct: 560 GYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANM 619
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN-LKVANLL 366
A+ A ++ PLH+AA+ V +AL++ A A + G+T LHLA + L V NLL
Sbjct: 620 GALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLL 679
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
H A K G TP H+AA A+ L+E GA TPL +A R +
Sbjct: 680 -EHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRK 737
Score = 97.9 bits (233), Expect = 3e-20
Identities = 59/172 (34%), Positives = 86/172 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+HLAA H +II +L + A + A TPLH+A+R G + LLQ G
Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A + PLH+A ++ L+EH+A + A K G+T HLAA GN +
Sbjct: 650 ADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILK 709
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
+L+ GA D TPL +A + +Q + + L +G + G P
Sbjct: 710 VLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL--EGKEPSVATLGGSKP 759
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/92 (36%), Positives = 44/92 (47%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
+N +TPLH LL D +G+TPL IAA+ Q + A LL +GA
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA 419
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N + G+ PLH AAQ G LLL+ G
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHG 451
Score = 45.2 bits (102), Expect = 2e-04
Identities = 21/61 (34%), Positives = 34/61 (55%)
Frame = +1
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+ +N TPLH + +E LL + + ++ +G+TPL +AAQ ++CALLL
Sbjct: 358 IYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAH 417
Query: 673 G 675
G
Sbjct: 418 G 418
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 protein.
Length = 765
Score = 167 bits (405), Expect = 5e-41
Identities = 85/222 (38%), Positives = 133/222 (59%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+AA H ++++L GA ++A+ R +TPLH+A G V LL+ GA
Sbjct: 494 GKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVP 553
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ Y PLH AA + + + L+ + A L T +G+T LHLAA G+L++ +LL
Sbjct: 554 DALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLA 613
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G TPLH+AA++ ++AV + LL+ GAD A ++G TPLH+A +++
Sbjct: 614 ESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFL 673
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LLE+ A +A +K G+TP HLAA +G+T + +L+E G
Sbjct: 674 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAG 715
Score = 147 bits (355), Expect = 5e-35
Identities = 77/220 (35%), Positives = 121/220 (55%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H + +R+LL + V+ + TPL IA++ D+ LLL HGAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D + PLH AA+ + A L++H A + A ++G+T LHLAA+ VA LL++
Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSR 483
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A P+ G TPLH+AA + ++ L +GA+ A +N TPLH+A + ++
Sbjct: 484 QADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAI 543
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ GA+ +A ++G+ PLH AA +G +C +LL G
Sbjct: 544 QHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYG 583
Score = 145 bits (352), Expect = 1e-34
Identities = 82/223 (36%), Positives = 121/223 (54%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ +AA+ D+ +LL +GA + PLH A++ G+ A LLL HG
Sbjct: 392 TASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHG 451
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A V A + + PLH+AA+ + +VA L+ A +G T LH+AA +G++ +
Sbjct: 452 ACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVK 511
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL + GA D +N TPLH+A + + LL+ GA A+ ++G+ PLH AA +
Sbjct: 512 LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARG 571
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL YGA + G+TPLHLAA +GH E+ LL E
Sbjct: 572 KYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAE 614
Score = 134 bits (323), Expect = 4e-31
Identities = 80/222 (36%), Positives = 112/222 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA+ R+LL +GA V+A+ RE TPLH+A++ ++A LL+ AD
Sbjct: 428 GWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADP 487
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ PLH+AA + + L A L A + T LHLA + G ++ LL
Sbjct: 488 NLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLL 547
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA PD ++G PLH AA + + LL GA + G TPLH+AA K +E
Sbjct: 548 KSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLE 607
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L E A A +TPLHLAA+ G + + LL+ G
Sbjct: 608 IIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649
Score = 131 bits (316), Expect = 3e-30
Identities = 73/209 (34%), Positives = 111/209 (53%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+HLAA+ N ++ R+L+ A E +TPLH+A+ G+V + LL GA++
Sbjct: 461 GWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAEL 520
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PLH+A ++ L++ A A + G+ LH AA G + +LL
Sbjct: 521 DAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLL 580
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA+ + G TPLH+AA + L E A+ A+ TPLH+AAR +
Sbjct: 581 RYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEA 640
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
+ LL+ GA NA ++G+TPLHLA Q+
Sbjct: 641 VVSALLQCGADPNAAEQSGWTPLHLAVQR 669
Score = 124 bits (298), Expect = 4e-28
Identities = 74/204 (36%), Positives = 106/204 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+HLA I+ LL++GA +A + PLH A+ G I +LL++GA +
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+AA + + ++ L E +A + A +T LHLAA++G V + LL
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQC 648
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA P+ A ++G TPLH+A Q LLE A+ A K G TP H+AA K
Sbjct: 649 GADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAIL 708
Query: 556 ATLLEYGALTNAESKAGFTPLHLA 627
L+E GA + + TPL LA
Sbjct: 709 KVLVEAGAQLDVQDGVSCTPLQLA 732
Score = 102 bits (244), Expect = 2e-21
Identities = 64/179 (35%), Positives = 94/179 (52%), Gaps = 1/179 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA I ++LLR GA++E + TPLH+A+ G+++I LL + A++
Sbjct: 560 GYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANM 619
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN-LKVANLL 366
A+ A ++ PLH+AA+ V +AL++ A A + G+T LHLA + L V NLL
Sbjct: 620 GALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLL 679
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
H A K G TP H+AA A+ L+E GA TPL +A R +
Sbjct: 680 -EHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRK 737
Score = 97.9 bits (233), Expect = 3e-20
Identities = 59/172 (34%), Positives = 86/172 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T +G TP+HLAA H +II +L + A + A TPLH+A+R G + LLQ G
Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG 649
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A + PLH+A ++ L+EH+A + A K G+T HLAA GN +
Sbjct: 650 ADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILK 709
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
+L+ GA D TPL +A + +Q + + L +G + G P
Sbjct: 710 VLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL--EGKEPSVATLGGSKP 759
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/92 (36%), Positives = 44/92 (47%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
+N +TPLH LL D +G+TPL IAA+ Q + A LL +GA
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA 419
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N + G+ PLH AAQ G LLL+ G
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHG 451
Score = 45.2 bits (102), Expect = 2e-04
Identities = 21/61 (34%), Positives = 34/61 (55%)
Frame = +1
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+ +N TPLH + +E LL + + ++ +G+TPL +AAQ ++CALLL
Sbjct: 358 IYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAH 417
Query: 673 G 675
G
Sbjct: 418 G 418
>BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1327
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 124/245 (50%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL +GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 683 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQDLL 801
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LLE GA
Sbjct: 802 RGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGA 861
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y NA K FTPLH AAQ+G T++CAL
Sbjct: 862 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 921
Query: 661 LLEGG 675
LL G
Sbjct: 922 LLAHG 926
Score = 118 bits (283), Expect = 3e-26
Identities = 87/244 (35%), Positives = 115/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +P+H AA D++ LL+ GA V A+ PLH A G+ ++ LLL GAD
Sbjct: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA---AKY---GNL 348
A +Y PLH AA + DV L++H A G +AL LA AK G
Sbjct: 275 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY 334
Query: 349 KVANLLLAHGAAPDQA-------------GKNGM--TPLHIAAQYDQQAVATTLLEKGAD 483
K LL A + ++ +G TPLH+AA Y++ + LL+ GAD
Sbjct: 335 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 394
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K G PLH A E LL++GA NA FTPLH AA + E+C+LL
Sbjct: 395 VHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 454
Query: 664 LEGG 675
L G
Sbjct: 455 LSHG 458
Score = 116 bits (279), Expect = 9e-26
Identities = 85/246 (34%), Positives = 119/246 (48%), Gaps = 23/246 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+R+GA+V + TPLH A+ G +I LLL+HGAD
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K+ + D+ L+ +A L KKG
Sbjct: 777 TKKNRDGNTPLDLV-KEGDTDIQD-LLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQ 834
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y +A L++
Sbjct: 835 GRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNT 894
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
A K TPLH AA+K + + A LL +GA +++ G TPL LA ++ AL
Sbjct: 895 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD---DIRAL 951
Query: 661 LLEGGP 678
L++ P
Sbjct: 952 LIDAMP 957
Score = 113 bits (272), Expect = 6e-25
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H D++ +L ++GA + A QT LH A+ G++ LLL +G+D
Sbjct: 560 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 619
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA- 372
I+ + A Q ++ ++ + P+ T+ + L A+K G+L+ L +
Sbjct: 620 ISLQGFT-----AAQMGNEAVQQILSESTPIR-TSDVDYRLLE-ASKAGDLETVKQLCSS 672
Query: 373 -HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D G++ TPLH AA Y++ +V LL GAD A K G PLH A E
Sbjct: 673 QNVNCRDLEGRHS-TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYE 731
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A L+ +GA N FTPLH AA +G E+C LLL+ G
Sbjct: 732 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG 773
Score = 109 bits (263), Expect = 8e-24
Identities = 81/247 (32%), Positives = 117/247 (47%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LLL+HGA
Sbjct: 368 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 427
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL------------- 327
V A+ + PLH AA ++ +V + L+ H A T G +A+ +
Sbjct: 428 VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYE 487
Query: 328 --------AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA---QYDQQAVATTLLEK 474
AA+ +L LA + ++ T LH A ++ V LL K
Sbjct: 488 FKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRK 547
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K+ TPLH+AA + + L ++GA NA G T LH AA GH + C
Sbjct: 548 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 607
Query: 655 ALLLEGG 675
LLL G
Sbjct: 608 RLLLSYG 614
Score = 109 bits (262), Expect = 1e-23
Identities = 76/222 (34%), Positives = 106/222 (47%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LL GA A+ TPLH A+ G +D+ ++LLQHGAD
Sbjct: 249 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 308
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L AA+ N + AL+ N A+ +
Sbjct: 309 NIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 368
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +++ LLL HGA K G+ PLH A Y V LL+ GA
Sbjct: 369 KSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV 428
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL +GA L N K+
Sbjct: 429 NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKS 470
Score = 93.9 bits (223), Expect = 5e-19
Identities = 81/233 (34%), Positives = 112/233 (48%), Gaps = 25/233 (10%)
Frame = +1
Query: 52 DIIRIL-LRNGAAVEAK--ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPL 222
D+ R+ L + A V AK A + +PLH A+ G D+ LLQ GA+V A PL
Sbjct: 194 DVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPL 253
Query: 223 HIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGK 402
H A + +V + L+ A A +T LH AA G + V +LL HGA P+
Sbjct: 254 HNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNT 313
Query: 403 NGMTPLHIAAQYDQQAVAT------TLLE---KGADAKAVA------KNGH-------TP 516
+G + L + A +AV T LLE G + K +A N H TP
Sbjct: 314 DGKSALDL-ADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTP 372
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LH+AA N++ LL++GA +A+ K G PLH A GH E+ LLL+ G
Sbjct: 373 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425
Score = 91.5 bits (217), Expect = 3e-18
Identities = 67/207 (32%), Positives = 96/207 (46%), Gaps = 27/207 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+ LLL+ GA+V D PLH+AA++ ++DV L +H A + A G TALH AA
Sbjct: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAA 599
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT-----------LLE--K 474
G+L+ LLL++G+ P G T + + QQ ++ + LLE K
Sbjct: 600 LAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASK 659
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V + TPLH AA N++ LL +GA +A+ K G
Sbjct: 660 AGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLV 719
Query: 613 PLHLAAQQGHTEMCALLLEGGPGTQFA 693
PLH A GH E+ LL+ G A
Sbjct: 720 PLHNACSYGHYEVAELLVRHGASVNVA 746
Score = 89.8 bits (213), Expect = 9e-18
Identities = 73/240 (30%), Positives = 113/240 (47%), Gaps = 25/240 (10%)
Frame = +1
Query: 31 AARA-NHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR+ N ++ +L A + TPLH+A+ V I LLLQHGADV A
Sbjct: 342 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 401
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
PLH A +++V L++H A + A FT LH AA ++V +LLL+HGA P
Sbjct: 402 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 461
Query: 388 DQAGKNGMTPLHIAAQYDQQAVAT------TLLEKGADA------KAVA---------KN 504
+G + + +A + + T +LL+ +A K +A ++
Sbjct: 462 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 521
Query: 505 GHTPLHIAA---RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A + + LL GA N ++K TPLH+AA++ H ++ +L + G
Sbjct: 522 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 581
Score = 87.8 bits (208), Expect = 4e-17
Identities = 67/218 (30%), Positives = 94/218 (43%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T +H AA A H R+LL G+ + + T A+++GN + +L +
Sbjct: 591 GQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGN-EAVQQILSESTPI 645
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
R D Y L + V N + T LH AA Y + V LL
Sbjct: 646 RTSDVD-YRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLL 704
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA K G+ PLH A Y VA L+ GA TPLH AA K + E
Sbjct: 705 HHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYE 764
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
LL++GA +++ G TPL L ++G T++ LL
Sbjct: 765 ICKLLLKHGADPTKKNRDGNTPLDL-VKEGDTDIQDLL 801
Score = 87.4 bits (207), Expect = 5e-17
Identities = 76/247 (30%), Positives = 108/247 (43%), Gaps = 24/247 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +LL++GA V A + TPLH A+ V++ LLL HGAD
Sbjct: 402 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 461
Query: 190 RAITADHYNPLHIAAKQH----------NHDVAAALIEHNAPLTATT-----------KK 306
+ + + +A H + A E + T +
Sbjct: 462 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 521
Query: 307 GFTALHLAAKYGNLK---VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
TALH A + K V LLL GA ++ K+ MTPLH+AA+ V L + G
Sbjct: 522 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 581
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A A+ G T LH AA ++T LL YG+ + S GFT AAQ G+ +
Sbjct: 582 AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQ 637
Query: 658 LLLEGGP 678
+L E P
Sbjct: 638 ILSESTP 644
Score = 81.4 bits (192), Expect = 3e-15
Identities = 65/204 (31%), Positives = 93/204 (45%), Gaps = 22/204 (10%)
Frame = +1
Query: 130 ASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK 306
AS+ G+++ + L + R + H PLH AA + V L+ H A + A K
Sbjct: 657 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 716
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
G LH A YG+ +VA LL+ HGA+ + A TPLH AA + + LL+ GAD
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 487 KAVAKNGHTPLHIAAR-----KNQMETAATLLE---YGALT-----------NAESKAG- 606
++G+TPL + ++ + A LL+ G L N G
Sbjct: 777 TKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 836
Query: 607 -FTPLHLAAQQGHTEMCALLLEGG 675
TPLHLAA + E+ LLE G
Sbjct: 837 NSTPLHLAAGYNNLEVAEYLLEHG 860
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/108 (38%), Positives = 61/108 (56%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL +GA V A+ + PLH A+ G+VDIA LL+++
Sbjct: 836 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC 895
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA 330
V A + PLH AA++ + A L+ H A T ++G T L LA
Sbjct: 896 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
>AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interacting
ankyrin-related ADP-ribose polymerase 2 protein.
Length = 1166
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 525 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 584
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 585 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 643
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763
Query: 661 LLEGG 675
LL G
Sbjct: 764 LLAHG 768
Score = 127 bits (307), Expect = 4e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 57 RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 116
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 117 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 176
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 177 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296
Query: 664 LEGG 675
L G
Sbjct: 297 LSYG 300
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 619 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 91 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 210
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 211 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 271 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 312
Score = 101 bits (242), Expect = 3e-21
Identities = 79/247 (31%), Positives = 115/247 (46%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 210 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 269
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-------N 345
V A+ + PLH AA ++ +V + L+ + A T +A+ LA
Sbjct: 270 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 329
Query: 346 LKVANLLLAHGAAPDQAGKNGM--------------TPLHIAAQYD---QQAVATTLLEK 474
K +LL A A K + T LH AA ++ + LL K
Sbjct: 330 FKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRK 389
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449
Query: 655 ALLLEGG 675
LLL G
Sbjct: 450 RLLLSYG 456
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 800
Query: 475 GA 480
A
Sbjct: 801 SA 802
Score = 96.7 bits (230), Expect = 8e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 55 AGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 114
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 115 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 173
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 174 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 233
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 234 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Score = 93.9 bits (223), Expect = 5e-19
Identities = 65/201 (32%), Positives = 98/201 (48%), Gaps = 27/201 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
I LLL+ GA++ T + PLH+A+++ ++DV +++H A + A G T+LH AA
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAA 441
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--K 474
G+L+ LLL++G P+ G T L + + QQ + LLE K
Sbjct: 442 YCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAK 501
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V K TPLH AA N++ LL++GA +A+ K G
Sbjct: 502 AGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLV 561
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A GH E+ LL++ G
Sbjct: 562 PLHNACSYGHYEVAELLVKHG 582
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 477 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 534
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 594
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 595 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Score = 81.0 bits (191), Expect = 4e-15
Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H A H ++ +L+++GA V A + TPLH A+ V++ LLL +GAD +
Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306
Query: 199 TADHYNPLHIA-AKQHNHDVAAALIEHN-------APLTATTKK------GF-------T 315
+ + + +A Q +A H+ A +T K F T
Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHET 366
Query: 316 ALHLAAK--YGNLK-VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
ALH AA Y K + LLL GA ++ K +TPLH+A++ V +++ A
Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A+ G T LH AA ++T LL YG N S GFT A Q G+ + LL
Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFT----ALQMGNENVQQLLQ 482
Query: 667 EG 672
EG
Sbjct: 483 EG 484
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 678 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 737
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 738 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 794
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 795 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 842
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 843 NLSGSFSELSSVVSSSGTEGASSL 866
Score = 68.5 bits (160), Expect = 2e-11
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 245
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 305
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL--HLAAQ 633
+ + + + +A E A + +L A +A T + HL+ +
Sbjct: 306 LNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLE 354
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 54 TAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 113
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 114 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 96 HNACSFGHAEVVNLLLRHG 114
>AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein.
Length = 1166
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 525 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 584
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 585 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 643
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763
Query: 661 LLEGG 675
LL G
Sbjct: 764 LLAHG 768
Score = 127 bits (307), Expect = 4e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 57 RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 116
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 117 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 176
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 177 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296
Query: 664 LEGG 675
L G
Sbjct: 297 LSYG 300
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 619 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 91 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 210
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 211 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 271 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 312
Score = 101 bits (242), Expect = 3e-21
Identities = 79/247 (31%), Positives = 115/247 (46%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 210 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 269
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-------N 345
V A+ + PLH AA ++ +V + L+ + A T +A+ LA
Sbjct: 270 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 329
Query: 346 LKVANLLLAHGAAPDQAGKNGM--------------TPLHIAAQYD---QQAVATTLLEK 474
K +LL A A K + T LH AA ++ + LL K
Sbjct: 330 FKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRK 389
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449
Query: 655 ALLLEGG 675
LLL G
Sbjct: 450 RLLLSYG 456
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 800
Query: 475 GA 480
A
Sbjct: 801 SA 802
Score = 96.7 bits (230), Expect = 8e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 55 AGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 114
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 115 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 173
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 174 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 233
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 234 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Score = 93.9 bits (223), Expect = 5e-19
Identities = 65/201 (32%), Positives = 98/201 (48%), Gaps = 27/201 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
I LLL+ GA++ T + PLH+A+++ ++DV +++H A + A G T+LH AA
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAA 441
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--K 474
G+L+ LLL++G P+ G T L + + QQ + LLE K
Sbjct: 442 YCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAK 501
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V K TPLH AA N++ LL++GA +A+ K G
Sbjct: 502 AGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLV 561
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A GH E+ LL++ G
Sbjct: 562 PLHNACSYGHYEVAELLVKHG 582
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 477 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 534
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 594
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 595 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Score = 81.0 bits (191), Expect = 4e-15
Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H A H ++ +L+++GA V A + TPLH A+ V++ LLL +GAD +
Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306
Query: 199 TADHYNPLHIA-AKQHNHDVAAALIEHN-------APLTATTKK------GF-------T 315
+ + + +A Q +A H+ A +T K F T
Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHET 366
Query: 316 ALHLAAK--YGNLK-VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
ALH AA Y K + LLL GA ++ K +TPLH+A++ V +++ A
Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A+ G T LH AA ++T LL YG N S GFT A Q G+ + LL
Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFT----ALQMGNENVQQLLQ 482
Query: 667 EG 672
EG
Sbjct: 483 EG 484
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 678 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 737
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 738 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 794
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 795 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 842
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 843 NLSGSFSELSSVVSSSGTEGASSL 866
Score = 68.5 bits (160), Expect = 2e-11
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 245
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 305
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL--HLAAQ 633
+ + + + +A E A + +L A +A T + HL+ +
Sbjct: 306 LNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLE 354
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 54 TAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 113
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 114 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 96 HNACSFGHAEVVNLLLRHG 114
>AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 525 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 584
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 585 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 643
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763
Query: 661 LLEGG 675
LL G
Sbjct: 764 LLAHG 768
Score = 127 bits (307), Expect = 4e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 57 RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 116
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 117 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 176
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 177 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296
Query: 664 LEGG 675
L G
Sbjct: 297 LSYG 300
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 619 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 91 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 210
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 211 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 271 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 312
Score = 101 bits (242), Expect = 3e-21
Identities = 79/247 (31%), Positives = 115/247 (46%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 210 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 269
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-------N 345
V A+ + PLH AA ++ +V + L+ + A T +A+ LA
Sbjct: 270 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 329
Query: 346 LKVANLLLAHGAAPDQAGKNGM--------------TPLHIAAQYD---QQAVATTLLEK 474
K +LL A A K + T LH AA ++ + LL K
Sbjct: 330 FKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRK 389
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449
Query: 655 ALLLEGG 675
LLL G
Sbjct: 450 RLLLSYG 456
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 800
Query: 475 GA 480
A
Sbjct: 801 SA 802
Score = 96.7 bits (230), Expect = 8e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 55 AGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 114
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 115 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 173
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 174 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 233
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 234 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Score = 93.9 bits (223), Expect = 5e-19
Identities = 65/201 (32%), Positives = 98/201 (48%), Gaps = 27/201 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
I LLL+ GA++ T + PLH+A+++ ++DV +++H A + A G T+LH AA
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAA 441
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--K 474
G+L+ LLL++G P+ G T L + + QQ + LLE K
Sbjct: 442 YCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAK 501
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V K TPLH AA N++ LL++GA +A+ K G
Sbjct: 502 AGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLV 561
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A GH E+ LL++ G
Sbjct: 562 PLHNACSYGHYEVAELLVKHG 582
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 477 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 534
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 594
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 595 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Score = 81.0 bits (191), Expect = 4e-15
Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H A H ++ +L+++GA V A + TPLH A+ V++ LLL +GAD +
Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306
Query: 199 TADHYNPLHIA-AKQHNHDVAAALIEHN-------APLTATTKK------GF-------T 315
+ + + +A Q +A H+ A +T K F T
Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHET 366
Query: 316 ALHLAAK--YGNLK-VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
ALH AA Y K + LLL GA ++ K +TPLH+A++ V +++ A
Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A+ G T LH AA ++T LL YG N S GFT A Q G+ + LL
Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFT----ALQMGNENVQQLLQ 482
Query: 667 EG 672
EG
Sbjct: 483 EG 484
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 678 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 737
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 738 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 794
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 795 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 842
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 843 NLSGSFSELSSVVSSSGTEGASSL 866
Score = 68.5 bits (160), Expect = 2e-11
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 245
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 305
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL--HLAAQ 633
+ + + + +A E A + +L A +A T + HL+ +
Sbjct: 306 LNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLE 354
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 54 TAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 113
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 114 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 96 HNACSFGHAEVVNLLLRHG 114
>AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 525 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 584
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 585 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 643
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763
Query: 661 LLEGG 675
LL G
Sbjct: 764 LLAHG 768
Score = 127 bits (307), Expect = 4e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 57 RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 116
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 117 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 176
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 177 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296
Query: 664 LEGG 675
L G
Sbjct: 297 LSYG 300
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 619 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 91 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 210
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 211 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 271 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 312
Score = 101 bits (242), Expect = 3e-21
Identities = 79/247 (31%), Positives = 115/247 (46%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 210 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 269
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-------N 345
V A+ + PLH AA ++ +V + L+ + A T +A+ LA
Sbjct: 270 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 329
Query: 346 LKVANLLLAHGAAPDQAGKNGM--------------TPLHIAAQYD---QQAVATTLLEK 474
K +LL A A K + T LH AA ++ + LL K
Sbjct: 330 FKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRK 389
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449
Query: 655 ALLLEGG 675
LLL G
Sbjct: 450 RLLLSYG 456
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 800
Query: 475 GA 480
A
Sbjct: 801 SA 802
Score = 96.7 bits (230), Expect = 8e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 55 AGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 114
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 115 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 173
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 174 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 233
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 234 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Score = 93.9 bits (223), Expect = 5e-19
Identities = 65/201 (32%), Positives = 98/201 (48%), Gaps = 27/201 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
I LLL+ GA++ T + PLH+A+++ ++DV +++H A + A G T+LH AA
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAA 441
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--K 474
G+L+ LLL++G P+ G T L + + QQ + LLE K
Sbjct: 442 YCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAK 501
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V K TPLH AA N++ LL++GA +A+ K G
Sbjct: 502 AGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLV 561
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A GH E+ LL++ G
Sbjct: 562 PLHNACSYGHYEVAELLVKHG 582
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 477 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 534
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 594
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 595 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Score = 81.0 bits (191), Expect = 4e-15
Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H A H ++ +L+++GA V A + TPLH A+ V++ LLL +GAD +
Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306
Query: 199 TADHYNPLHIA-AKQHNHDVAAALIEHN-------APLTATTKK------GF-------T 315
+ + + +A Q +A H+ A +T K F T
Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHET 366
Query: 316 ALHLAAK--YGNLK-VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
ALH AA Y K + LLL GA ++ K +TPLH+A++ V +++ A
Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A+ G T LH AA ++T LL YG N S GFT A Q G+ + LL
Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFT----ALQMGNENVQQLLQ 482
Query: 667 EG 672
EG
Sbjct: 483 EG 484
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 678 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 737
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 738 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 794
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 795 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 842
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 843 NLSGSFSELSSVVSSSGTEGASSL 866
Score = 68.5 bits (160), Expect = 2e-11
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 245
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 305
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL--HLAAQ 633
+ + + + +A E A + +L A +A T + HL+ +
Sbjct: 306 LNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLE 354
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 54 TAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 113
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 114 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 96 HNACSFGHAEVVNLLLRHG 114
>AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein.
Length = 1166
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 525 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 584
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 585 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 643
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763
Query: 661 LLEGG 675
LL G
Sbjct: 764 LLAHG 768
Score = 127 bits (307), Expect = 4e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 57 RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 116
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 117 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 176
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 177 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296
Query: 664 LEGG 675
L G
Sbjct: 297 LSYG 300
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 619 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 91 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 210
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 211 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 271 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 312
Score = 101 bits (242), Expect = 3e-21
Identities = 79/247 (31%), Positives = 115/247 (46%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 210 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 269
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-------N 345
V A+ + PLH AA ++ +V + L+ + A T +A+ LA
Sbjct: 270 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 329
Query: 346 LKVANLLLAHGAAPDQAGKNGM--------------TPLHIAAQYD---QQAVATTLLEK 474
K +LL A A K + T LH AA ++ + LL K
Sbjct: 330 FKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRK 389
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449
Query: 655 ALLLEGG 675
LLL G
Sbjct: 450 RLLLSYG 456
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 800
Query: 475 GA 480
A
Sbjct: 801 SA 802
Score = 96.7 bits (230), Expect = 8e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 55 AGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 114
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 115 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 173
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 174 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 233
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 234 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Score = 93.9 bits (223), Expect = 5e-19
Identities = 65/201 (32%), Positives = 98/201 (48%), Gaps = 27/201 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
I LLL+ GA++ T + PLH+A+++ ++DV +++H A + A G T+LH AA
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAA 441
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--K 474
G+L+ LLL++G P+ G T L + + QQ + LLE K
Sbjct: 442 YCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAK 501
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V K TPLH AA N++ LL++GA +A+ K G
Sbjct: 502 AGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLV 561
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A GH E+ LL++ G
Sbjct: 562 PLHNACSYGHYEVAELLVKHG 582
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 477 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 534
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 594
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 595 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Score = 81.0 bits (191), Expect = 4e-15
Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H A H ++ +L+++GA V A + TPLH A+ V++ LLL +GAD +
Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306
Query: 199 TADHYNPLHIA-AKQHNHDVAAALIEHN-------APLTATTKK------GF-------T 315
+ + + +A Q +A H+ A +T K F T
Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHET 366
Query: 316 ALHLAAK--YGNLK-VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
ALH AA Y K + LLL GA ++ K +TPLH+A++ V +++ A
Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A+ G T LH AA ++T LL YG N S GFT A Q G+ + LL
Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFT----ALQMGNENVQQLLQ 482
Query: 667 EG 672
EG
Sbjct: 483 EG 484
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 678 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 737
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 738 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 794
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 795 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 842
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 843 NLSGSFSELSSVVSSSGTEGASSL 866
Score = 68.5 bits (160), Expect = 2e-11
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 245
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 305
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL--HLAAQ 633
+ + + + +A E A + +L A +A T + HL+ +
Sbjct: 306 LNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLE 354
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 54 TAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 113
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 114 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 96 HNACSFGHAEVVNLLLRHG 114
>AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related protein
protein.
Length = 1265
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 624 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 683
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 684 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 742
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 743 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 802
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 803 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 862
Query: 661 LLEGG 675
LL G
Sbjct: 863 LLAHG 867
Score = 128 bits (308), Expect = 3e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 157 RKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 216
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 217 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 276
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 277 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 336
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 337 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 396
Query: 664 LEGG 675
L G
Sbjct: 397 LSYG 400
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 658 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 717
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 718 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 775
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 776 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 835
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 836 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 885
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 191 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 250
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 251 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 310
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 311 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 370
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 371 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 412
Score = 104 bits (249), Expect = 4e-22
Identities = 78/246 (31%), Positives = 115/246 (46%), Gaps = 23/246 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 310 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 369
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------AKYGNL 348
V A+ + PLH AA ++ +V + L+ + A T +A+ LA +
Sbjct: 370 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 429
Query: 349 KVANLLLAHGAAPD--------------QAGKNGMTPLHIAAQY---DQQAVATTLLEKG 477
L+ A D QA + T LH AA ++ + LL KG
Sbjct: 430 FQRPLVAAXAREADVTRIKKHLSLEMVIQASQTHETALHCAAASPYPKRKQICELLLRKG 489
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 490 ANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCR 549
Query: 658 LLLEGG 675
LLL G
Sbjct: 550 LLLSYG 555
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 780 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 839
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 840 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 899
Query: 475 GA 480
A
Sbjct: 900 SA 901
Score = 99.1 bits (236), Expect = 1e-20
Identities = 76/247 (30%), Positives = 116/247 (46%), Gaps = 31/247 (12%)
Frame = +1
Query: 28 LAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLG---NVDIAVLLLQHGADVRA 195
+AA A D+ RI + +A + +T LH A+ I LLL+ GA++
Sbjct: 435 VAAXAREADVTRIKKHLSLEMVIQASQTHETALHCAAASPYPKRKQICELLLRKGANINE 494
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+A+++ ++DV +++H A + A G T+LH AA G+L+ LLL++
Sbjct: 495 KTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSY 554
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--KGADAKAVAK----- 501
G P+ G T L + + QQ + LLE K D + V K
Sbjct: 555 GCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQ 614
Query: 502 ---------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
TPLH AA N++ LL++GA +A+ K G PLH A GH E+
Sbjct: 615 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 674
Query: 655 ALLLEGG 675
LL++ G
Sbjct: 675 ELLVKHG 681
Score = 97.1 bits (231), Expect = 6e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 155 AGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 214
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 215 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 273
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 274 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 333
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 334 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 367
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 576 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 633
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 634 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 693
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 694 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 730
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 777 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 836
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 837 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 893
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 894 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 941
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 942 NLSGSFSELSSVVSSSGTEGASSL 965
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 154 TAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 213
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 214 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 264
Score = 66.1 bits (154), Expect = 1e-10
Identities = 55/202 (27%), Positives = 86/202 (42%), Gaps = 21/202 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 226 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 285
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 286 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 345
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 346 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 405
Query: 493 VAKNGHTPLHIAARKNQMETAA 558
+ + + + +A E A
Sbjct: 406 LNCHNKSAIDLAPTPQLKERLA 427
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 136 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPL 195
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 196 HNACSFGHAEVVNLLLRHG 214
>AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein
protein.
Length = 1166
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 126/245 (51%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL++GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 525 RQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV 584
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 585 VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLL 643
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LL+ GA
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y A NA K FTPLH AAQ+G T++CAL
Sbjct: 704 DVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCAL 763
Query: 661 LLEGG 675
LL G
Sbjct: 764 LLAHG 768
Score = 127 bits (307), Expect = 4e-29
Identities = 88/244 (36%), Positives = 116/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA D++ LL+NGA V+A+ PLH A G+ ++ LLL+HGAD
Sbjct: 57 RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD 116
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA------------ 330
A +Y PLH AA + DV L++H A T G TAL LA
Sbjct: 117 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY 176
Query: 331 --------AKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A+ GN K+ LL + TPLH+AA Y++ + LL+ GAD
Sbjct: 177 KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD 236
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K PLH A E L+++GA NA FTPLH AA + E+C+LL
Sbjct: 237 VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296
Query: 664 LEGG 675
L G
Sbjct: 297 LSYG 300
Score = 114 bits (275), Expect = 3e-25
Identities = 82/230 (35%), Positives = 110/230 (47%), Gaps = 23/230 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+++GA V + TPLH A+ G +I LLLQHGAD
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K + D+ L+ +A L KKG
Sbjct: 619 TKKNRDGNTPLDLV-KDGDTDIQD-LLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y VA L++ A
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
A K TPLH AA+K + + A LL +GA +++ G TPL L +
Sbjct: 737 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Score = 109 bits (263), Expect = 8e-24
Identities = 75/222 (33%), Positives = 108/222 (48%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LLR+GA A+ TPLH A+ G +D+ ++LLQHGA+
Sbjct: 91 GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L +A+ N + AL+ N A+ +
Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR 210
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +K+ LLL HGA K + PLH A Y V L++ GA
Sbjct: 211 KSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL YGA L N +K+
Sbjct: 271 NAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKS 312
Score = 101 bits (242), Expect = 3e-21
Identities = 79/247 (31%), Positives = 115/247 (46%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LL++HGA
Sbjct: 210 RKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGAC 269
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-------N 345
V A+ + PLH AA ++ +V + L+ + A T +A+ LA
Sbjct: 270 VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYE 329
Query: 346 LKVANLLLAHGAAPDQAGKNGM--------------TPLHIAAQYD---QQAVATTLLEK 474
K +LL A A K + T LH AA ++ + LL K
Sbjct: 330 FKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRK 389
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K TPLH+A+ K + ++++ A NA G T LH AA GH + C
Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449
Query: 655 ALLLEGG 675
LLL G
Sbjct: 450 RLLLSYG 456
Score = 101 bits (242), Expect = 3e-21
Identities = 55/122 (45%), Positives = 72/122 (59%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH+A+ N+++A LLQHGADV A PLH AA + DVAA LI++NA + A
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T K FT LH AA+ G ++ LLLAHGA P + G TPL + + D A+ T +
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPP 800
Query: 475 GA 480
A
Sbjct: 801 SA 802
Score = 96.7 bits (230), Expect = 8e-20
Identities = 75/214 (35%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Frame = +1
Query: 100 ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
A + TPLH A+ G D+ LLQ+GA+V+A PLH A + +V L+ H
Sbjct: 55 AGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHG 114
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT 459
A A +T LH AA G + V +LL HGA P +G T L + A +AV T
Sbjct: 115 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDL-ADPSAKAVLT 173
Query: 460 ------TLLE---KGADAKAVA------KNGH-------TPLHIAARKNQMETAATLLEY 573
LLE G + K +A N H TPLH+AA N+++ LL++
Sbjct: 174 GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH 233
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GA +A+ K PLH A GH E+ LL++ G
Sbjct: 234 GADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Score = 93.9 bits (223), Expect = 5e-19
Identities = 65/201 (32%), Positives = 98/201 (48%), Gaps = 27/201 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
I LLL+ GA++ T + PLH+A+++ ++DV +++H A + A G T+LH AA
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAA 441
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT-----------TLLE--K 474
G+L+ LLL++G P+ G T L + + QQ + LLE K
Sbjct: 442 YCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAK 501
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V K TPLH AA N++ LL++GA +A+ K G
Sbjct: 502 AGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLV 561
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A GH E+ LL++ G
Sbjct: 562 PLHNACSYGHYEVAELLVKHG 582
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAA 234
++ LL+ G ++ +RQ L A++ G+V+ + L + R I PLH AA
Sbjct: 477 VQQLLQEGISLGNSEADRQ--LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAA 534
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
+ V L++H A + A K G LH A YG+ +VA LL+ HGA + A T
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFT 594
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
PLH AA + + LL+ GAD ++G+TPL +
Sbjct: 595 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDL 631
Score = 81.0 bits (191), Expect = 4e-15
Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H A H ++ +L+++GA V A + TPLH A+ V++ LLL +GAD +
Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306
Query: 199 TADHYNPLHIA-AKQHNHDVAAALIEHN-------APLTATTKK------GF-------T 315
+ + + +A Q +A H+ A +T K F T
Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHET 366
Query: 316 ALHLAAK--YGNLK-VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
ALH AA Y K + LLL GA ++ K +TPLH+A++ V +++ A
Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A+ G T LH AA ++T LL YG N S GFT A Q G+ + LL
Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFT----ALQMGNENVQQLLQ 482
Query: 667 EG 672
EG
Sbjct: 483 EG 484
Score = 77.0 bits (181), Expect = 7e-14
Identities = 59/204 (28%), Positives = 98/204 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL++GA V A+ + PLH A+ G+VD+A LL+++ A
Sbjct: 678 RHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC 737
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A + PLH AA++ + A L+ H A T ++G T L L + V+ LL
Sbjct: 738 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD---DVSALL 794
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
A M P + + Y Q V + GA A A++ +P ++A +
Sbjct: 795 TA-----------AMPPSALPSCYKPQ-VLNGVRSPGATADALSSGPSSPSSLSAASSLD 842
Query: 547 ETAATLLEYGALTNAESKAGFTPL 618
+ + E ++ ++ G + L
Sbjct: 843 NLSGSFSELSSVVSSSGTEGASSL 866
Score = 68.5 bits (160), Expect = 2e-11
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIA--------------------S 135
TP+H AA D+ +LL++GA + + +T L +A +
Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185
Query: 136 RLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF 312
R GN + + LL + A PLH+AA + + L++H A + A K
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDL 245
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
LH A YG+ +V LL+ HGA + TPLH AA ++ V + LL GAD
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTL 305
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL--HLAAQ 633
+ + + + +A E A + +L A +A T + HL+ +
Sbjct: 306 LNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLE 354
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/111 (36%), Positives = 52/111 (46%)
Frame = +1
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T + T LH AA +G V LL +GA G+ PLH A + V LL
Sbjct: 54 TAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH 113
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
GAD A +TPLH AA K +++ LL++GA + G T L LA
Sbjct: 114 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/79 (32%), Positives = 36/79 (45%)
Frame = +1
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
D + V + + +++ A TPLH AA + + LL+ GA A G PL
Sbjct: 36 DVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPL 95
Query: 619 HLAAQQGHTEMCALLLEGG 675
H A GH E+ LLL G
Sbjct: 96 HNACSFGHAEVVNLLLRHG 114
>AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1094
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 124/245 (50%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL +GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 450 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 509
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 510 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQDLL 568
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LLE GA
Sbjct: 569 KGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGA 628
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y NA K FTPLH AAQ+G T++CAL
Sbjct: 629 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 688
Query: 661 LLEGG 675
LL G
Sbjct: 689 LLAHG 693
Score = 116 bits (280), Expect = 7e-26
Identities = 85/246 (34%), Positives = 120/246 (48%), Gaps = 23/246 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+R+GA+V + TPLH A+ G +I LLL+HGAD
Sbjct: 484 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 543
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K+ + D+ L++ +A L KKG
Sbjct: 544 TKKNRDGNTPLDLV-KEGDTDIQD-LLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQ 601
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y +A L++
Sbjct: 602 GRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNT 661
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
A K TPLH AA+K + + A LL +GA +++ G TPL LA ++ AL
Sbjct: 662 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD---DIRAL 718
Query: 661 LLEGGP 678
L++ P
Sbjct: 719 LIDAMP 724
Score = 116 bits (278), Expect = 1e-25
Identities = 81/223 (36%), Positives = 108/223 (48%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H +++ +LL GA A+ TPLH A+ G +D+ ++LLQHGAD
Sbjct: 16 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 75
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNL-KVANLL 366
D + L +A D +A A LT KK L AA+ GN K+ LL
Sbjct: 76 NIRNTDGKSALDLA------DPSA-----KAVLTGEYKKD--ELLEAARSGNEEKLMALL 122
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
+ TPLH+AA Y++ + LL+ GAD A K G PLH A
Sbjct: 123 TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY 182
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL++GA NA FTPLH AA + E+C+LLL G
Sbjct: 183 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 225
Score = 113 bits (272), Expect = 6e-25
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H D++ +L ++GA + A QT LH A+ G++ LLL +G+D
Sbjct: 327 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 386
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA- 372
I+ + A Q ++ ++ + P+ T+ + L A+K G+L+ L +
Sbjct: 387 ISLQGFT-----AAQMGNEAVQQILSESTPIR-TSDVDYRLLE-ASKAGDLETVKQLCSS 439
Query: 373 -HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D G++ TPLH AA Y++ +V LL GAD A K G PLH A E
Sbjct: 440 QNVNCRDLEGRHS-TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYE 498
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A L+ +GA N FTPLH AA +G E+C LLL+ G
Sbjct: 499 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG 540
Score = 109 bits (263), Expect = 8e-24
Identities = 81/247 (32%), Positives = 117/247 (47%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LLL+HGA
Sbjct: 135 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 194
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL------------- 327
V A+ + PLH AA ++ +V + L+ H A T G +A+ +
Sbjct: 195 VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYE 254
Query: 328 --------AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA---QYDQQAVATTLLEK 474
AA+ +L LA + ++ T LH A ++ V LL K
Sbjct: 255 FKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRK 314
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K+ TPLH+AA + + L ++GA NA G T LH AA GH + C
Sbjct: 315 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 374
Query: 655 ALLLEGG 675
LLL G
Sbjct: 375 RLLLSYG 381
Score = 91.5 bits (217), Expect = 3e-18
Identities = 67/207 (32%), Positives = 96/207 (46%), Gaps = 27/207 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+ LLL+ GA+V D PLH+AA++ ++DV L +H A + A G TALH AA
Sbjct: 307 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAA 366
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT-----------LLE--K 474
G+L+ LLL++G+ P G T + + QQ ++ + LLE K
Sbjct: 367 LAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASK 426
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V + TPLH AA N++ LL +GA +A+ K G
Sbjct: 427 AGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLV 486
Query: 613 PLHLAAQQGHTEMCALLLEGGPGTQFA 693
PLH A GH E+ LL+ G A
Sbjct: 487 PLHNACSYGHYEVAELLVRHGASVNVA 513
Score = 89.8 bits (213), Expect = 9e-18
Identities = 73/240 (30%), Positives = 113/240 (47%), Gaps = 25/240 (10%)
Frame = +1
Query: 31 AARA-NHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR+ N ++ +L A + TPLH+A+ V I LLLQHGADV A
Sbjct: 109 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 168
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
PLH A +++V L++H A + A FT LH AA ++V +LLL+HGA P
Sbjct: 169 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 228
Query: 388 DQAGKNGMTPLHIAAQYDQQAVAT------TLLEKGADA------KAVA---------KN 504
+G + + +A + + T +LL+ +A K +A ++
Sbjct: 229 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 288
Query: 505 GHTPLHIAA---RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A + + LL GA N ++K TPLH+AA++ H ++ +L + G
Sbjct: 289 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 348
Score = 87.8 bits (208), Expect = 4e-17
Identities = 67/218 (30%), Positives = 94/218 (43%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T +H AA A H R+LL G+ + + T A+++GN + +L +
Sbjct: 358 GQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGN-EAVQQILSESTPI 412
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
R D Y L + V N + T LH AA Y + V LL
Sbjct: 413 RTSDVD-YRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLL 471
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA K G+ PLH A Y VA L+ GA TPLH AA K + E
Sbjct: 472 HHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYE 531
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
LL++GA +++ G TPL L ++G T++ LL
Sbjct: 532 ICKLLLKHGADPTKKNRDGNTPLDL-VKEGDTDIQDLL 568
Score = 87.4 bits (207), Expect = 5e-17
Identities = 76/247 (30%), Positives = 108/247 (43%), Gaps = 24/247 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +LL++GA V A + TPLH A+ V++ LLL HGAD
Sbjct: 169 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 228
Query: 190 RAITADHYNPLHIAAKQH----------NHDVAAALIEHNAPLTATT-----------KK 306
+ + + +A H + A E + T +
Sbjct: 229 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 288
Query: 307 GFTALHLAAKYGNLK---VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
TALH A + K V LLL GA ++ K+ MTPLH+AA+ V L + G
Sbjct: 289 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 348
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A A+ G T LH AA ++T LL YG+ + S GFT AAQ G+ +
Sbjct: 349 AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQ 404
Query: 658 LLLEGGP 678
+L E P
Sbjct: 405 ILSESTP 411
Score = 81.8 bits (193), Expect = 2e-15
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 22/204 (10%)
Frame = +1
Query: 130 ASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK 306
AS+ G+++ + L + R + H PLH AA + V L+ H A + A K
Sbjct: 424 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 483
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
G LH A YG+ +VA LL+ HGA+ + A TPLH AA + + LL+ GAD
Sbjct: 484 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 543
Query: 487 KAVAKNGHTPLHIAAR-----KNQMETAATLLE---YGALT-----------NAESKAG- 606
++G+TPL + ++ ++ A LL+ G L N G
Sbjct: 544 TKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 603
Query: 607 -FTPLHLAAQQGHTEMCALLLEGG 675
TPLHLAA + E+ LLE G
Sbjct: 604 NSTPLHLAAGYNNLEVAEYLLEHG 627
Score = 77.4 bits (182), Expect = 5e-14
Identities = 67/192 (34%), Positives = 91/192 (47%), Gaps = 22/192 (11%)
Frame = +1
Query: 166 LLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
LLQ GA+V A PLH A + +V + L+ A A +T LH AA G
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGK 61
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVAT------TLLE---KGADAKAVA 498
+ V +LL HGA P+ +G + L + A +AV T LLE G + K +A
Sbjct: 62 IDVCIVLLQHGADPNIRNTDGKSALDL-ADPSAKAVLTGEYKKDELLEAARSGNEEKLMA 120
Query: 499 ------KNGH-------TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQG 639
N H TPLH+AA N++ LL++GA +A+ K G PLH A G
Sbjct: 121 LLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYG 180
Query: 640 HTEMCALLLEGG 675
H E+ LLL+ G
Sbjct: 181 HYEVTELLLKHG 192
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/108 (38%), Positives = 61/108 (56%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL +GA V A+ + PLH A+ G+VDIA LL+++
Sbjct: 603 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC 662
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA 330
V A + PLH AA++ + A L+ H A T ++G T L LA
Sbjct: 663 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 710
>AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1327
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 124/245 (50%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL +GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 683 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQDLL 801
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LLE GA
Sbjct: 802 KGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGA 861
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y NA K FTPLH AAQ+G T++CAL
Sbjct: 862 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 921
Query: 661 LLEGG 675
LL G
Sbjct: 922 LLAHG 926
Score = 118 bits (283), Expect = 3e-26
Identities = 87/244 (35%), Positives = 115/244 (47%), Gaps = 21/244 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +P+H AA D++ LL+ GA V A+ PLH A G+ ++ LLL GAD
Sbjct: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA---AKY---GNL 348
A +Y PLH AA + DV L++H A G +AL LA AK G
Sbjct: 275 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY 334
Query: 349 KVANLLLAHGAAPDQA-------------GKNGM--TPLHIAAQYDQQAVATTLLEKGAD 483
K LL A + ++ +G TPLH+AA Y++ + LL+ GAD
Sbjct: 335 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 394
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
A K G PLH A E LL++GA NA FTPLH AA + E+C+LL
Sbjct: 395 VHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 454
Query: 664 LEGG 675
L G
Sbjct: 455 LSHG 458
Score = 116 bits (280), Expect = 7e-26
Identities = 85/246 (34%), Positives = 120/246 (48%), Gaps = 23/246 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+R+GA+V + TPLH A+ G +I LLL+HGAD
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K+ + D+ L++ +A L KKG
Sbjct: 777 TKKNRDGNTPLDLV-KEGDTDIQD-LLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQ 834
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y +A L++
Sbjct: 835 GRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNT 894
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
A K TPLH AA+K + + A LL +GA +++ G TPL LA ++ AL
Sbjct: 895 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD---DIRAL 951
Query: 661 LLEGGP 678
L++ P
Sbjct: 952 LIDAMP 957
Score = 113 bits (272), Expect = 6e-25
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H D++ +L ++GA + A QT LH A+ G++ LLL +G+D
Sbjct: 560 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 619
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA- 372
I+ + A Q ++ ++ + P+ T+ + L A+K G+L+ L +
Sbjct: 620 ISLQGFT-----AAQMGNEAVQQILSESTPIR-TSDVDYRLLE-ASKAGDLETVKQLCSS 672
Query: 373 -HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D G++ TPLH AA Y++ +V LL GAD A K G PLH A E
Sbjct: 673 QNVNCRDLEGRHS-TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYE 731
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A L+ +GA N FTPLH AA +G E+C LLL+ G
Sbjct: 732 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG 773
Score = 109 bits (263), Expect = 8e-24
Identities = 81/247 (32%), Positives = 117/247 (47%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LLL+HGA
Sbjct: 368 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 427
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL------------- 327
V A+ + PLH AA ++ +V + L+ H A T G +A+ +
Sbjct: 428 VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYE 487
Query: 328 --------AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA---QYDQQAVATTLLEK 474
AA+ +L LA + ++ T LH A ++ V LL K
Sbjct: 488 FKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRK 547
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K+ TPLH+AA + + L ++GA NA G T LH AA GH + C
Sbjct: 548 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 607
Query: 655 ALLLEGG 675
LLL G
Sbjct: 608 RLLLSYG 614
Score = 109 bits (262), Expect = 1e-23
Identities = 76/222 (34%), Positives = 106/222 (47%), Gaps = 24/222 (10%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G P+H A H +++ +LL GA A+ TPLH A+ G +D+ ++LLQHGAD
Sbjct: 249 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 308
Query: 187 -----------------VRAITADHY--NPLHIAAKQHNHDVAAALIEH-NAPLTATTKK 306
+A+ Y + L AA+ N + AL+ N A+ +
Sbjct: 309 NIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 368
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
T LHLAA Y +++ LLL HGA K G+ PLH A Y V LL+ GA
Sbjct: 369 KSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV 428
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGA---LTNAESKA 603
A+ TPLH AA KN++E + LL +GA L N K+
Sbjct: 429 NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKS 470
Score = 93.9 bits (223), Expect = 5e-19
Identities = 81/233 (34%), Positives = 112/233 (48%), Gaps = 25/233 (10%)
Frame = +1
Query: 52 DIIRIL-LRNGAAVEAK--ARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPL 222
D+ R+ L + A V AK A + +PLH A+ G D+ LLQ GA+V A PL
Sbjct: 194 DVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPL 253
Query: 223 HIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGK 402
H A + +V + L+ A A +T LH AA G + V +LL HGA P+
Sbjct: 254 HNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNT 313
Query: 403 NGMTPLHIAAQYDQQAVAT------TLLE---KGADAKAVA------KNGH-------TP 516
+G + L + A +AV T LLE G + K +A N H TP
Sbjct: 314 DGKSALDL-ADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTP 372
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LH+AA N++ LL++GA +A+ K G PLH A GH E+ LLL+ G
Sbjct: 373 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425
Score = 91.5 bits (217), Expect = 3e-18
Identities = 67/207 (32%), Positives = 96/207 (46%), Gaps = 27/207 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+ LLL+ GA+V D PLH+AA++ ++DV L +H A + A G TALH AA
Sbjct: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAA 599
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT-----------LLE--K 474
G+L+ LLL++G+ P G T + + QQ ++ + LLE K
Sbjct: 600 LAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASK 659
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V + TPLH AA N++ LL +GA +A+ K G
Sbjct: 660 AGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLV 719
Query: 613 PLHLAAQQGHTEMCALLLEGGPGTQFA 693
PLH A GH E+ LL+ G A
Sbjct: 720 PLHNACSYGHYEVAELLVRHGASVNVA 746
Score = 89.8 bits (213), Expect = 9e-18
Identities = 73/240 (30%), Positives = 113/240 (47%), Gaps = 25/240 (10%)
Frame = +1
Query: 31 AARA-NHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR+ N ++ +L A + TPLH+A+ V I LLLQHGADV A
Sbjct: 342 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 401
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
PLH A +++V L++H A + A FT LH AA ++V +LLL+HGA P
Sbjct: 402 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 461
Query: 388 DQAGKNGMTPLHIAAQYDQQAVAT------TLLEKGADA------KAVA---------KN 504
+G + + +A + + T +LL+ +A K +A ++
Sbjct: 462 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 521
Query: 505 GHTPLHIAA---RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A + + LL GA N ++K TPLH+AA++ H ++ +L + G
Sbjct: 522 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 581
Score = 87.8 bits (208), Expect = 4e-17
Identities = 67/218 (30%), Positives = 94/218 (43%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T +H AA A H R+LL G+ + + T A+++GN + +L +
Sbjct: 591 GQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGN-EAVQQILSESTPI 645
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
R D Y L + V N + T LH AA Y + V LL
Sbjct: 646 RTSDVD-YRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLL 704
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA K G+ PLH A Y VA L+ GA TPLH AA K + E
Sbjct: 705 HHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYE 764
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
LL++GA +++ G TPL L ++G T++ LL
Sbjct: 765 ICKLLLKHGADPTKKNRDGNTPLDL-VKEGDTDIQDLL 801
Score = 87.4 bits (207), Expect = 5e-17
Identities = 76/247 (30%), Positives = 108/247 (43%), Gaps = 24/247 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +LL++GA V A + TPLH A+ V++ LLL HGAD
Sbjct: 402 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 461
Query: 190 RAITADHYNPLHIAAKQH----------NHDVAAALIEHNAPLTATT-----------KK 306
+ + + +A H + A E + T +
Sbjct: 462 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 521
Query: 307 GFTALHLAAKYGNLK---VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
TALH A + K V LLL GA ++ K+ MTPLH+AA+ V L + G
Sbjct: 522 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 581
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A A+ G T LH AA ++T LL YG+ + S GFT AAQ G+ +
Sbjct: 582 AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQ 637
Query: 658 LLLEGGP 678
+L E P
Sbjct: 638 ILSESTP 644
Score = 81.8 bits (193), Expect = 2e-15
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 22/204 (10%)
Frame = +1
Query: 130 ASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK 306
AS+ G+++ + L + R + H PLH AA + V L+ H A + A K
Sbjct: 657 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 716
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
G LH A YG+ +VA LL+ HGA+ + A TPLH AA + + LL+ GAD
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 487 KAVAKNGHTPLHIAAR-----KNQMETAATLLE---YGALT-----------NAESKAG- 606
++G+TPL + ++ ++ A LL+ G L N G
Sbjct: 777 TKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 836
Query: 607 -FTPLHLAAQQGHTEMCALLLEGG 675
TPLHLAA + E+ LLE G
Sbjct: 837 NSTPLHLAAGYNNLEVAEYLLEHG 860
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/108 (38%), Positives = 61/108 (56%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL +GA V A+ + PLH A+ G+VDIA LL+++
Sbjct: 836 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC 895
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA 330
V A + PLH AA++ + A L+ H A T ++G T L LA
Sbjct: 896 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
>AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interacting
ankyrin-related ADP-ribose polymerase variant protein.
Length = 1055
Score = 148 bits (358), Expect = 2e-35
Identities = 93/245 (37%), Positives = 124/245 (50%), Gaps = 22/245 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+H AA N ++ LL +GA V AK + PLH A G+ ++A LL++HGA
Sbjct: 411 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 470
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PLH AA + +++ L++H A T + G T L L K G+ + +LL
Sbjct: 471 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQDLL 529
Query: 367 LAHGAAPDQAGKNGM----------------------TPLHIAAQYDQQAVATTLLEKGA 480
A D A K + TPLH+AA Y+ VA LLE GA
Sbjct: 530 RGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGA 589
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D A K G PLH AA ++ AA L++Y NA K FTPLH AAQ+G T++CAL
Sbjct: 590 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 649
Query: 661 LLEGG 675
LL G
Sbjct: 650 LLAHG 654
Score = 116 bits (279), Expect = 9e-26
Identities = 85/246 (34%), Positives = 119/246 (48%), Gaps = 23/246 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +L+R+GA+V + TPLH A+ G +I LLL+HGAD
Sbjct: 445 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 504
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF------------------- 312
D PL + K+ + D+ L+ +A L KKG
Sbjct: 505 TKKNRDGNTPLDLV-KEGDTDIQD-LLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQ 562
Query: 313 ----TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
T LHLAA Y NL+VA LL HGA + K G+ PLH AA Y +A L++
Sbjct: 563 GRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNT 622
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
A K TPLH AA+K + + A LL +GA +++ G TPL LA ++ AL
Sbjct: 623 CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD---DIRAL 679
Query: 661 LLEGGP 678
L++ P
Sbjct: 680 LIDAMP 685
Score = 113 bits (272), Expect = 6e-25
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA H D++ +L ++GA + A QT LH A+ G++ LLL +G+D
Sbjct: 288 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 347
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA- 372
I+ + A Q ++ ++ + P+ T+ + L A+K G+L+ L +
Sbjct: 348 ISLQGFT-----AAQMGNEAVQQILSESTPIR-TSDVDYRLLE-ASKAGDLETVKQLCSS 400
Query: 373 -HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ D G++ TPLH AA Y++ +V LL GAD A K G PLH A E
Sbjct: 401 QNVNCRDLEGRHS-TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYE 459
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A L+ +GA N FTPLH AA +G E+C LLL+ G
Sbjct: 460 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG 501
Score = 109 bits (263), Expect = 8e-24
Identities = 81/247 (32%), Positives = 117/247 (47%), Gaps = 24/247 (9%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N I+++LL++GA V AK + PLH A G+ ++ LLL+HGA
Sbjct: 96 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 155
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL------------- 327
V A+ + PLH AA ++ +V + L+ H A T G +A+ +
Sbjct: 156 VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYE 215
Query: 328 --------AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA---QYDQQAVATTLLEK 474
AA+ +L LA + ++ T LH A ++ V LL K
Sbjct: 216 FKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRK 275
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
GA+ K+ TPLH+AA + + L ++GA NA G T LH AA GH + C
Sbjct: 276 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 335
Query: 655 ALLLEGG 675
LLL G
Sbjct: 336 RLLLSYG 342
Score = 98.3 bits (234), Expect = 3e-20
Identities = 71/188 (37%), Positives = 92/188 (48%), Gaps = 1/188 (0%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G +D+ ++LLQHGAD D + L +A D +A A LT
Sbjct: 12 TPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA------DPSA-----KAVLTG 60
Query: 295 TTKKGFTALHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
KK L AA+ GN K+ LL + TPLH+AA Y++ + LL+
Sbjct: 61 EYKKD--ELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQ 118
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
GAD A K G PLH A E LL++GA NA FTPLH AA + E+
Sbjct: 119 HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEV 178
Query: 652 CALLLEGG 675
C+LLL G
Sbjct: 179 CSLLLSHG 186
Score = 91.5 bits (217), Expect = 3e-18
Identities = 67/207 (32%), Positives = 96/207 (46%), Gaps = 27/207 (13%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+ LLL+ GA+V D PLH+AA++ ++DV L +H A + A G TALH AA
Sbjct: 268 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAA 327
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT-----------LLE--K 474
G+L+ LLL++G+ P G T + + QQ ++ + LLE K
Sbjct: 328 LAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASK 387
Query: 475 GADAKAVAK--------------NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
D + V + TPLH AA N++ LL +GA +A+ K G
Sbjct: 388 AGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLV 447
Query: 613 PLHLAAQQGHTEMCALLLEGGPGTQFA 693
PLH A GH E+ LL+ G A
Sbjct: 448 PLHNACSYGHYEVAELLVRHGASVNVA 474
Score = 89.8 bits (213), Expect = 9e-18
Identities = 73/240 (30%), Positives = 113/240 (47%), Gaps = 25/240 (10%)
Frame = +1
Query: 31 AARA-NHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR+ N ++ +L A + TPLH+A+ V I LLLQHGADV A
Sbjct: 70 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 129
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
PLH A +++V L++H A + A FT LH AA ++V +LLL+HGA P
Sbjct: 130 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 189
Query: 388 DQAGKNGMTPLHIAAQYDQQAVAT------TLLEKGADA------KAVA---------KN 504
+G + + +A + + T +LL+ +A K +A ++
Sbjct: 190 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 249
Query: 505 GHTPLHIAA---RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A + + LL GA N ++K TPLH+AA++ H ++ +L + G
Sbjct: 250 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 309
Score = 87.8 bits (208), Expect = 4e-17
Identities = 67/218 (30%), Positives = 94/218 (43%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T +H AA A H R+LL G+ + + T A+++GN + +L +
Sbjct: 319 GQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGN-EAVQQILSESTPI 373
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
R D Y L + V N + T LH AA Y + V LL
Sbjct: 374 RTSDVD-YRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLL 432
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA K G+ PLH A Y VA L+ GA TPLH AA K + E
Sbjct: 433 HHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYE 492
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
LL++GA +++ G TPL L ++G T++ LL
Sbjct: 493 ICKLLLKHGADPTKKNRDGNTPLDL-VKEGDTDIQDLL 529
Score = 87.4 bits (207), Expect = 5e-17
Identities = 76/247 (30%), Positives = 108/247 (43%), Gaps = 24/247 (9%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H A H ++ +LL++GA V A + TPLH A+ V++ LLL HGAD
Sbjct: 130 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 189
Query: 190 RAITADHYNPLHIAAKQH----------NHDVAAALIEHNAPLTATT-----------KK 306
+ + + +A H + A E + T +
Sbjct: 190 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 249
Query: 307 GFTALHLAAKYGNLK---VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
TALH A + K V LLL GA ++ K+ MTPLH+AA+ V L + G
Sbjct: 250 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 309
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A A+ G T LH AA ++T LL YG+ + S GFT AAQ G+ +
Sbjct: 310 AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQ 365
Query: 658 LLLEGGP 678
+L E P
Sbjct: 366 ILSESTP 372
Score = 81.4 bits (192), Expect = 3e-15
Identities = 65/204 (31%), Positives = 93/204 (45%), Gaps = 22/204 (10%)
Frame = +1
Query: 130 ASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK 306
AS+ G+++ + L + R + H PLH AA + V L+ H A + A K
Sbjct: 385 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 444
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
G LH A YG+ +VA LL+ HGA+ + A TPLH AA + + LL+ GAD
Sbjct: 445 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 504
Query: 487 KAVAKNGHTPLHIAAR-----KNQMETAATLLE---YGALT-----------NAESKAG- 606
++G+TPL + ++ + A LL+ G L N G
Sbjct: 505 TKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 564
Query: 607 -FTPLHLAAQQGHTEMCALLLEGG 675
TPLHLAA + E+ LLE G
Sbjct: 565 NSTPLHLAAGYNNLEVAEYLLEHG 588
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/108 (38%), Positives = 61/108 (56%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R TP+HLAA N+ ++ LL +GA V A+ + PLH A+ G+VDIA LL+++
Sbjct: 564 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC 623
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA 330
V A + PLH AA++ + A L+ H A T ++G T L LA
Sbjct: 624 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 671
Score = 33.9 bits (74), Expect = 0.61
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +1
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
AD A +TPLH AA K +++ LL++GA N + G + L LA
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 50
Score = 31.1 bits (67), Expect = 4.3
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
NA +TPLH AA +G ++C +LL+ G
Sbjct: 4 NARDNWNYTPLHEAAIKGKIDVCIVLLQHG 33
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 142 bits (343), Expect = 2e-33
Identities = 79/226 (34%), Positives = 116/226 (51%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA H +++ +LL GA + A ++ + LH A+ +G++D+ LL+ HGA+V
Sbjct: 140 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 199
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA +V L+ + G TALH+A G V N L+
Sbjct: 200 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 259
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
+GA +Q NG TPLH AA A+ LL GAD +K+G +PLH+ A +
Sbjct: 260 DYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRF 319
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ TL++ G + K G TPLH+AA+ GH + L+ G T
Sbjct: 320 TRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 365
Score = 130 bits (315), Expect = 4e-30
Identities = 80/222 (36%), Positives = 108/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA +++ ++V R +T LH A+ G+V++ LLL GA++
Sbjct: 108 QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANIN 167
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A LH AA + DV A LI H A +T KKG+T LH AA G + V LL
Sbjct: 168 AFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLN 227
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G D+ G T LHIA Q AV L++ GA+ NG TPLH AA
Sbjct: 228 LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL 287
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G +PLH+ A G L++ G
Sbjct: 288 CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNG 329
Score = 126 bits (305), Expect = 6e-29
Identities = 76/217 (35%), Positives = 107/217 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++L+++ A V A+ + QTPLH+A+ V A +++ + V
Sbjct: 76 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 135
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK ALH AA G+L V LL+ H
Sbjct: 136 SDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINH 195
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K G TPLH AA Q V LL G + + G+T LHIA Q
Sbjct: 196 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 255
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L++YGA N + GFTPLH AA H +C LL
Sbjct: 256 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELL 292
Score = 120 bits (289), Expect = 5e-27
Identities = 75/220 (34%), Positives = 108/220 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA +II +L+ +GA V AK TPLH A + + +L++H ADV A
Sbjct: 43 TPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNA 102
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA A +I + + + + G TALH AA G++++ NLLLA
Sbjct: 103 RDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAK 162
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K LH AA V L+ GA+ K G+TPLH AA Q+
Sbjct: 163 GANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVV 222
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + + G T LH+A G + L++ G
Sbjct: 223 KHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG 262
Score = 116 bits (279), Expect = 9e-26
Identities = 71/221 (32%), Positives = 108/221 (48%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+ P+ A + + IR+L+ V E++TPLH+A+ LG+ +I LL+ GA V
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVN 68
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A PLH A + + LI+H+A + A K T LH+AA +K A +++
Sbjct: 69 AKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIP 128
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
++ + + + G T LH AA + LL KGA+ A K LH AA ++
Sbjct: 129 LLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDV 188
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A L+ +GA + K G+TPLH AA G + LL G
Sbjct: 189 VALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLG 229
Score = 89.8 bits (213), Expect = 9e-18
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 1/160 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G TP+H AA ++++ LL G ++ T LHIA G + L+ +GA+
Sbjct: 205 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 264
Query: 187 VRAITADHYNPLHI-AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V + + PLH AA H L+ + A + +K G + LH+ A +G +
Sbjct: 265 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 324
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
L+ +G D K+G TPLH+AA+Y + + TL+ GAD
Sbjct: 325 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 364
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHG 180
V G T +H+A ++ L+ GA V TPLH A+ + + + LL+ +G
Sbjct: 237 VYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNG 296
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
ADV + D +PLH+ A + LI++ + K G T LH+AA+YG+ + N
Sbjct: 297 ADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLIN 356
Query: 361 LLLAHGA 381
L+ GA
Sbjct: 357 TLITSGA 363
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 142 bits (343), Expect = 2e-33
Identities = 79/226 (34%), Positives = 116/226 (51%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA H +++ +LL GA + A ++ + LH A+ +G++D+ LL+ HGA+V
Sbjct: 79 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 138
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA +V L+ + G TALH+A G V N L+
Sbjct: 139 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 198
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
+GA +Q NG TPLH AA A+ LL GAD +K+G +PLH+ A +
Sbjct: 199 DYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRF 258
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ TL++ G + K G TPLH+AA+ GH + L+ G T
Sbjct: 259 TRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 304
Score = 130 bits (315), Expect = 4e-30
Identities = 80/222 (36%), Positives = 108/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA +++ ++V R +T LH A+ G+V++ LLL GA++
Sbjct: 47 QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANIN 106
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A LH AA + DV A LI H A +T KKG+T LH AA G + V LL
Sbjct: 107 AFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLN 166
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G D+ G T LHIA Q AV L++ GA+ NG TPLH AA
Sbjct: 167 LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL 226
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G +PLH+ A G L++ G
Sbjct: 227 CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNG 268
Score = 126 bits (305), Expect = 6e-29
Identities = 76/217 (35%), Positives = 107/217 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++L+++ A V A+ + QTPLH+A+ V A +++ + V
Sbjct: 15 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 74
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK ALH AA G+L V LL+ H
Sbjct: 75 SDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINH 134
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K G TPLH AA Q V LL G + + G+T LHIA Q
Sbjct: 135 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 194
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L++YGA N + GFTPLH AA H +C LL
Sbjct: 195 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELL 231
Score = 103 bits (248), Expect = 5e-22
Identities = 67/200 (33%), Positives = 95/200 (47%)
Frame = +1
Query: 76 NGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDV 255
+GA V AK TPLH A + + +L++H ADV A + PLH+AA
Sbjct: 2 SGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKC 61
Query: 256 AAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQ 435
A +I + + + + G TALH AA G++++ NLLLA GA + K LH AA
Sbjct: 62 AEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAY 121
Query: 436 YDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTP 615
V L+ GA+ K G+TPLH AA Q+ LL G + + G T
Sbjct: 122 MGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTA 181
Query: 616 LHLAAQQGHTEMCALLLEGG 675
LH+A G + L++ G
Sbjct: 182 LHIACYNGQDAVVNELIDYG 201
Score = 89.8 bits (213), Expect = 9e-18
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 1/160 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G TP+H AA ++++ LL G ++ T LHIA G + L+ +GA+
Sbjct: 144 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 203
Query: 187 VRAITADHYNPLHI-AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V + + PLH AA H L+ + A + +K G + LH+ A +G +
Sbjct: 204 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 263
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
L+ +G D K+G TPLH+AA+Y + + TL+ GAD
Sbjct: 264 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 303
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHG 180
V G T +H+A ++ L+ GA V TPLH A+ + + + LL+ +G
Sbjct: 176 VYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNG 235
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
ADV + D +PLH+ A + LI++ + K G T LH+AA+YG+ + N
Sbjct: 236 ADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLIN 295
Query: 361 LLLAHGA 381
L+ GA
Sbjct: 296 TLITSGA 302
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 142 bits (343), Expect = 2e-33
Identities = 79/226 (34%), Positives = 116/226 (51%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA H +++ +LL GA + A ++ + LH A+ +G++D+ LL+ HGA+V
Sbjct: 140 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 199
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA +V L+ + G TALH+A G V N L+
Sbjct: 200 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 259
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
+GA +Q NG TPLH AA A+ LL GAD +K+G +PLH+ A +
Sbjct: 260 DYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRF 319
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ TL++ G + K G TPLH+AA+ GH + L+ G T
Sbjct: 320 TRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 365
Score = 130 bits (315), Expect = 4e-30
Identities = 80/222 (36%), Positives = 108/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA +++ ++V R +T LH A+ G+V++ LLL GA++
Sbjct: 108 QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANIN 167
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A LH AA + DV A LI H A +T KKG+T LH AA G + V LL
Sbjct: 168 AFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLN 227
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G D+ G T LHIA Q AV L++ GA+ NG TPLH AA
Sbjct: 228 LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL 287
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G +PLH+ A G L++ G
Sbjct: 288 CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNG 329
Score = 126 bits (305), Expect = 6e-29
Identities = 76/217 (35%), Positives = 107/217 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++L+++ A V A+ + QTPLH+A+ V A +++ + V
Sbjct: 76 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 135
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK ALH AA G+L V LL+ H
Sbjct: 136 SDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINH 195
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K G TPLH AA Q V LL G + + G+T LHIA Q
Sbjct: 196 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 255
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L++YGA N + GFTPLH AA H +C LL
Sbjct: 256 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELL 292
Score = 120 bits (289), Expect = 5e-27
Identities = 75/220 (34%), Positives = 108/220 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA +II +L+ +GA V AK TPLH A + + +L++H ADV A
Sbjct: 43 TPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNA 102
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA A +I + + + + G TALH AA G++++ NLLLA
Sbjct: 103 RDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAK 162
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K LH AA V L+ GA+ K G+TPLH AA Q+
Sbjct: 163 GANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVV 222
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + + G T LH+A G + L++ G
Sbjct: 223 KHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG 262
Score = 116 bits (279), Expect = 9e-26
Identities = 71/221 (32%), Positives = 108/221 (48%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+ P+ A + + IR+L+ V E++TPLH+A+ LG+ +I LL+ GA V
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVN 68
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A PLH A + + LI+H+A + A K T LH+AA +K A +++
Sbjct: 69 AKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIP 128
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
++ + + + G T LH AA + LL KGA+ A K LH AA ++
Sbjct: 129 LLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDV 188
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A L+ +GA + K G+TPLH AA G + LL G
Sbjct: 189 VALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLG 229
Score = 116 bits (278), Expect = 1e-25
Identities = 70/224 (31%), Positives = 105/224 (46%), Gaps = 1/224 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G TP+H AA ++++ LL G ++ T LHIA G + L+ +GA+
Sbjct: 205 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 264
Query: 187 VRAITADHYNPLHI-AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V + + PLH AA H L+ + A + +K G + LH+ A +G +
Sbjct: 265 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 324
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
L+ +G D K+G TPLH+AA+Y + + TL+ GAD + PLH+AA
Sbjct: 325 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAH 384
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL G + K G T LH AA G+ E LL G
Sbjct: 385 SDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSG 428
Score = 110 bits (264), Expect = 6e-24
Identities = 72/225 (32%), Positives = 103/225 (45%), Gaps = 1/225 (0%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHG 180
V G T +H+A ++ L+ GA V TPLH A+ + + + LL+ +G
Sbjct: 237 VYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNG 296
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
ADV + D +PLH+ A + LI++ + K G T LH+AA+YG+ + N
Sbjct: 297 ADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLIN 356
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ GA + G + M PLH+AA LL G + K G T LH AA
Sbjct: 357 TLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGG 416
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E L GA + + K G TPLH AA H L+ G
Sbjct: 417 NVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTG 461
Score = 101 bits (242), Expect = 3e-21
Identities = 67/208 (32%), Positives = 94/208 (45%), Gaps = 1/208 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+H AA + H + + +L+ NGA V ++++ ++PLH+ + G + L+Q+G +
Sbjct: 272 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 331
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + D PLH+AA+ + + LI A LHLAA + L
Sbjct: 332 IDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKL 391
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L+ G D K G T LH AA L GAD K G TPLH AA
Sbjct: 392 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHF 451
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAA 630
TL+ GA N G T LH AA
Sbjct: 452 HCIETLVTTGANVNETDDWGRTALHYAA 479
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/186 (31%), Positives = 88/186 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G++P+H+ A + L++NG ++ ++ TPLH+A+R G+ + L+ GAD
Sbjct: 306 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 365
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA + D L+ + K G T LH AA GN++ LL
Sbjct: 366 AKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQ 425
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ GA + K G TPLH AA TL+ GA+ G T LH AA + M+
Sbjct: 426 SSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAA-ASDMD 484
Query: 550 TAATLL 567
T+L
Sbjct: 485 RNKTIL 490
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/119 (24%), Positives = 53/119 (44%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AA H I L+ GA V +T LH A+ ++D +L + D
Sbjct: 438 GRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAA-SDMDRNKTILGNAHD- 495
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
++ ++ L++++A + K+G+ ++H AA YG+ + L+
Sbjct: 496 ---NSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELV 551
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 142 bits (343), Expect = 2e-33
Identities = 79/226 (34%), Positives = 116/226 (51%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA H +++ +LL GA + A ++ + LH A+ +G++D+ LL+ HGA+V
Sbjct: 115 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 174
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA +V L+ + G TALH+A G V N L+
Sbjct: 175 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 234
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
+GA +Q NG TPLH AA A+ LL GAD +K+G +PLH+ A +
Sbjct: 235 DYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRF 294
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ TL++ G + K G TPLH+AA+ GH + L+ G T
Sbjct: 295 TRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 340
Score = 130 bits (315), Expect = 4e-30
Identities = 80/222 (36%), Positives = 108/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA +++ ++V R +T LH A+ G+V++ LLL GA++
Sbjct: 83 QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANIN 142
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A LH AA + DV A LI H A +T KKG+T LH AA G + V LL
Sbjct: 143 AFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLN 202
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G D+ G T LHIA Q AV L++ GA+ NG TPLH AA
Sbjct: 203 LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL 262
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G +PLH+ A G L++ G
Sbjct: 263 CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNG 304
Score = 126 bits (305), Expect = 6e-29
Identities = 76/217 (35%), Positives = 107/217 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++L+++ A V A+ + QTPLH+A+ V A +++ + V
Sbjct: 51 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 110
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK ALH AA G+L V LL+ H
Sbjct: 111 SDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINH 170
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K G TPLH AA Q V LL G + + G+T LHIA Q
Sbjct: 171 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 230
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L++YGA N + GFTPLH AA H +C LL
Sbjct: 231 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELL 267
Score = 120 bits (289), Expect = 5e-27
Identities = 75/220 (34%), Positives = 108/220 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA +II +L+ +GA V AK TPLH A + + +L++H ADV A
Sbjct: 18 TPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNA 77
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA A +I + + + + G TALH AA G++++ NLLLA
Sbjct: 78 RDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAK 137
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K LH AA V L+ GA+ K G+TPLH AA Q+
Sbjct: 138 GANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVV 197
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + + G T LH+A G + L++ G
Sbjct: 198 KHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG 237
Score = 116 bits (278), Expect = 1e-25
Identities = 70/224 (31%), Positives = 105/224 (46%), Gaps = 1/224 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G TP+H AA ++++ LL G ++ T LHIA G + L+ +GA+
Sbjct: 180 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 239
Query: 187 VRAITADHYNPLHI-AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V + + PLH AA H L+ + A + +K G + LH+ A +G +
Sbjct: 240 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 299
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
L+ +G D K+G TPLH+AA+Y + + TL+ GAD + PLH+AA
Sbjct: 300 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAH 359
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL G + K G T LH AA G+ E LL G
Sbjct: 360 SDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSG 403
Score = 111 bits (268), Expect = 2e-24
Identities = 67/204 (32%), Positives = 100/204 (49%)
Frame = +1
Query: 64 ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
+L+ V E++TPLH+A+ LG+ +I LL+ GA V A PLH A
Sbjct: 1 MLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASR 60
Query: 244 NHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLH 423
+ + LI+H+A + A K T LH+AA +K A +++ ++ + + + G T LH
Sbjct: 61 SEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALH 120
Query: 424 IAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKA 603
AA + LL KGA+ A K LH AA ++ A L+ +GA + K
Sbjct: 121 HAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKK 180
Query: 604 GFTPLHLAAQQGHTEMCALLLEGG 675
G+TPLH AA G + LL G
Sbjct: 181 GYTPLHAAASNGQINVVKHLLNLG 204
Score = 110 bits (264), Expect = 6e-24
Identities = 72/225 (32%), Positives = 103/225 (45%), Gaps = 1/225 (0%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHG 180
V G T +H+A ++ L+ GA V TPLH A+ + + + LL+ +G
Sbjct: 212 VYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNG 271
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
ADV + D +PLH+ A + LI++ + K G T LH+AA+YG+ + N
Sbjct: 272 ADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLIN 331
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ GA + G + M PLH+AA LL G + K G T LH AA
Sbjct: 332 TLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGG 391
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E L GA + + K G TPLH AA H L+ G
Sbjct: 392 NVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTG 436
Score = 101 bits (242), Expect = 3e-21
Identities = 67/208 (32%), Positives = 94/208 (45%), Gaps = 1/208 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+H AA + H + + +L+ NGA V ++++ ++PLH+ + G + L+Q+G +
Sbjct: 247 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 306
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + D PLH+AA+ + + LI A LHLAA + L
Sbjct: 307 IDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKL 366
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L+ G D K G T LH AA L GAD K G TPLH AA
Sbjct: 367 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHF 426
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAA 630
TL+ GA N G T LH AA
Sbjct: 427 HCIETLVTTGANVNETDDWGRTALHYAA 454
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/186 (31%), Positives = 88/186 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G++P+H+ A + L++NG ++ ++ TPLH+A+R G+ + L+ GAD
Sbjct: 281 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 340
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA + D L+ + K G T LH AA GN++ LL
Sbjct: 341 AKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQ 400
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ GA + K G TPLH AA TL+ GA+ G T LH AA + M+
Sbjct: 401 SSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAA-ASDMD 459
Query: 550 TAATLL 567
T+L
Sbjct: 460 RNKTIL 465
Score = 35.5 bits (78), Expect = 0.20
Identities = 29/118 (24%), Positives = 52/118 (44%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H AA H I L+ GA V +T LH A+ ++D +L + D
Sbjct: 413 GRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAA-SDMDRNKTILGNAHD- 470
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
++ ++ L++++A + K+G+ ++H AA YG+ + L
Sbjct: 471 ---NSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLEL 525
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 141 bits (342), Expect = 2e-33
Identities = 77/226 (34%), Positives = 119/226 (52%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++++LL GA + A ++ + +H A+ +G++++ LL+ HGA+V
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA V L++ + G T LH+A G V N L+
Sbjct: 233 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 292
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
GA +Q + G TPLH AA A+ LL GAD +K+G TPLH+ A +
Sbjct: 293 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRF 352
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ T+++ GA+ + E K G TPLH+AA+ GH + L+ G T
Sbjct: 353 SRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Score = 130 bits (314), Expect = 5e-30
Identities = 76/219 (34%), Positives = 112/219 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++LL++ A V A+ + QTPLHIA+ V A L+ ++V
Sbjct: 109 TPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 168
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK A+H AA G+++V LL++H
Sbjct: 169 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSH 228
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K TPLH AA +V LL+ G D G+TPLH+A Q
Sbjct: 229 GAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 288
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L++ GA+ N +++ GFTPLH AA H +C LL G
Sbjct: 289 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVG 327
Score = 118 bits (283), Expect = 3e-26
Identities = 75/220 (34%), Positives = 107/220 (48%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA +II +L+ +GA V AK + TPLH A + + +LL+H ADV A
Sbjct: 76 TPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNA 135
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLHIAA A AL+ + + + + G TALH AA G+ ++ LLL+
Sbjct: 136 RDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSR 195
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K +H AA V L+ GA+ K +TPLH AA +
Sbjct: 196 GANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVV 255
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ G N + G TPLH+A G + L++ G
Sbjct: 256 KYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 295
Score = 116 bits (278), Expect = 1e-25
Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA L+ + V R +T LH A+ G+ ++ LLL GA++
Sbjct: 141 QTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 200
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A +H AA + +V L+ H A +T KK +T LH AA G + V LL
Sbjct: 201 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 260
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G ++ G TPLH+A Q V L++ GA + G TPLH AA
Sbjct: 261 LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL 320
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G TPLH+ A G +++ G
Sbjct: 321 CLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSG 362
Score = 114 bits (274), Expect = 4e-25
Identities = 73/221 (33%), Positives = 101/221 (45%), Gaps = 1/221 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + +++ LL G + TPLH+A G + L+ GA V
Sbjct: 241 TPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 300
Query: 196 ITADHYNPLHIAAKQ-HNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ PLH AA H L+ + A + +K G T LH+ A +G + ++
Sbjct: 301 KNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQ 360
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA D KNG TPLHIAA+Y + + TL+ GAD +G PLH+AA +
Sbjct: 361 SGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC 420
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + G T LH AA G+ E LLL G
Sbjct: 421 CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTG 461
Score = 114 bits (274), Expect = 4e-25
Identities = 75/222 (33%), Positives = 106/222 (47%), Gaps = 1/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHGAD 186
G TP+H+A ++ L+ GA V K + TPLH A+ + + + LL+ +GAD
Sbjct: 272 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGAD 331
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + D PLH+ A + +I+ A + K G T LH+AA+YG+ + N L
Sbjct: 332 VNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 391
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
+ GA + G +GM PLH+AA LL G D G T LH AA +
Sbjct: 392 ITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNL 451
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
E LL GA N + K G +PLH AA + + C L G
Sbjct: 452 ECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQ-CLFALVG 492
Score = 106 bits (254), Expect = 9e-23
Identities = 66/208 (31%), Positives = 100/208 (48%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D +R L+ V + E++TPLH A+ LG+ +I LL+ GA V A + PLH A
Sbjct: 55 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRA 114
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
+ + L++H+A + A K T LH+AA +K A L+ + + + + G
Sbjct: 115 VASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR 174
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T LH AA + LL +GA+ A K +H AA +E L+ +GA
Sbjct: 175 TALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTC 234
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ K +TPLH AA G + LL+ G
Sbjct: 235 KDKKSYTPLHAAASSGMISVVKYLLDLG 262
Score = 105 bits (253), Expect = 1e-22
Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+ A + ++++GA ++ + + TPLHIA+R G+ + L+ GAD
Sbjct: 339 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA D L+ + G T LH AA GNL+ NLLL
Sbjct: 399 AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 458
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN-QM 546
GA ++ K G +PLH AA L+ GA + + G TPLH AA +
Sbjct: 459 NTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG 518
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ LL A K G+ +H +A GH +C L+
Sbjct: 519 KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH-RLCLQLI 557
Score = 103 bits (247), Expect = 7e-22
Identities = 71/217 (32%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+H AA + H + + +L+ NGA V K+++ +TPLH+ + G + ++Q GA
Sbjct: 304 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 363
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLHIAA+ + + LI A G LHLAA G
Sbjct: 364 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 423
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL+ G D G T LH AA LL GAD K G +PLH AA
Sbjct: 424 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN 483
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
+ L+ GA N + G TPLH AA C
Sbjct: 484 YQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKC 520
Score = 91.9 bits (218), Expect = 2e-18
Identities = 74/237 (31%), Positives = 110/237 (46%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G P+HLAA + +D R LL +G ++ +T LH A+ GN++ LLL GA
Sbjct: 403 IHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 462
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-NLKVAN 360
D +PLH AA N+ AL+ A + ++G T LH AA + K
Sbjct: 463 DFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLE 522
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQ----QAVAT-----TLLE-KGADAKAVAKNGH 510
LL + A P K G +H +A Y Q +A+ L+E G D + + N
Sbjct: 523 YLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRA 582
Query: 511 T--PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T PLH+AA + L++ + + +G TPL LAA +GH E +L+ G
Sbjct: 583 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 639
Score = 77.4 bits (182), Expect = 5e-14
Identities = 57/178 (32%), Positives = 75/178 (42%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G+ D L+ DV + PLH AA + ++ LI A + A K T L
Sbjct: 52 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 111
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
H A + + +LL H A + KN TPLHIAA A L+ ++ +
Sbjct: 112 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 171
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA E LL GA NA K +H AA GH E+ LL+ G
Sbjct: 172 AGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 229
Score = 77.0 bits (181), Expect = 7e-14
Identities = 70/243 (28%), Positives = 108/243 (44%), Gaps = 20/243 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTD--IIRILLRNGAAVEAKARERQTPLHIASRLGN----------V 150
RG TP+H AA ++ TD + LLRN A + ++ +H ++ G+
Sbjct: 503 RGCTPLHYAATSD-TDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 151 DIAVLLLQHGADVRAITADH--YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALH 324
+ VL+ G D+ + + + +PLH+AA +H L++ L G T L
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 621
Query: 325 LAAKYGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
LAA G+++ ++L+ GA+ D K TP+H AA L+ AV
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDYILKR--TPIHAAATNGHSECLRLLIGNAEPQNAV 679
Query: 496 A---KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
NG TPL ++ + +LL GA +A+ K G T LH A GH E LL
Sbjct: 680 DIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 739
Query: 667 EGG 675
+ G
Sbjct: 740 QHG 742
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/226 (27%), Positives = 98/226 (43%), Gaps = 4/226 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ ETP+ + + TD++ ++ R +PLH+A+ G+ +L+Q
Sbjct: 557 IASETPLDVLMETSGTDMLS---------DSDNRATISPLHLAAYHGHHQALEVLVQSLL 607
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTK-KGFTALHLAAKYGNLKVAN 360
D+ + PL +AA + + + LI A + T +H AA G+ +
Sbjct: 608 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 667
Query: 361 LLLAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
LL+ + A D NG TPL ++ +LL KGA+ A K G T LH A
Sbjct: 668 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 727
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
E LL++GA G TP+HL+A GH + LL+
Sbjct: 728 VTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 773
Score = 73.3 bits (172), Expect = 8e-13
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 4/165 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ LAA H + + +L+ GA++ K ++TP+H A+ G+ + LL+ +
Sbjct: 616 GRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEP 675
Query: 187 VRAITADHYN---PLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+ N PL ++ + D +L+ A + A K G TALH A G+ +
Sbjct: 676 QNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECV 735
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
+ LL HGA G TP+H++A V LL+ A A
Sbjct: 736 DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDA 780
Score = 72.5 bits (170), Expect = 1e-12
Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 6/198 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+HLAA H + +L+++ ++ + +TPL +A+ G+V+ +L+ GA +
Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-- 642
Query: 196 ITADHY---NPLHIAAKQHNHDVAAALIEHNAPLTATTKK---GFTALHLAAKYGNLKVA 357
+ D+ P+H AA + + LI + P A + G T L L+ G+
Sbjct: 643 LVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 702
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LL GA D K G T LH A + LL+ GA G TP+H++A
Sbjct: 703 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 762
Query: 538 NQMETAATLLEYGALTNA 591
+ LL+ A +A
Sbjct: 763 GHIGVLGALLQSAASMDA 780
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/30 (40%), Positives = 21/30 (70%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEA 96
RG TP+HL+A H ++ LL++ A+++A
Sbjct: 751 RGRTPIHLSAACGHIGVLGALLQSAASMDA 780
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 141 bits (342), Expect = 2e-33
Identities = 77/226 (34%), Positives = 119/226 (52%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++++LL GA + A ++ + +H A+ +G++++ LL+ HGA+V
Sbjct: 170 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 229
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA V L++ + G T LH+A G V N L+
Sbjct: 230 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 289
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
GA +Q + G TPLH AA A+ LL GAD +K+G TPLH+ A +
Sbjct: 290 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRF 349
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ T+++ GA+ + E K G TPLH+AA+ GH + L+ G T
Sbjct: 350 SRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 395
Score = 130 bits (314), Expect = 5e-30
Identities = 76/219 (34%), Positives = 112/219 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++LL++ A V A+ + QTPLHIA+ V A L+ ++V
Sbjct: 106 TPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 165
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK A+H AA G+++V LL++H
Sbjct: 166 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSH 225
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K TPLH AA +V LL+ G D G+TPLH+A Q
Sbjct: 226 GAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 285
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L++ GA+ N +++ GFTPLH AA H +C LL G
Sbjct: 286 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVG 324
Score = 118 bits (283), Expect = 3e-26
Identities = 75/220 (34%), Positives = 107/220 (48%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA +II +L+ +GA V AK + TPLH A + + +LL+H ADV A
Sbjct: 73 TPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNA 132
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLHIAA A AL+ + + + + G TALH AA G+ ++ LLL+
Sbjct: 133 RDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSR 192
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K +H AA V L+ GA+ K +TPLH AA +
Sbjct: 193 GANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVV 252
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ G N + G TPLH+A G + L++ G
Sbjct: 253 KYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 292
Score = 116 bits (278), Expect = 1e-25
Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA L+ + V R +T LH A+ G+ ++ LLL GA++
Sbjct: 138 QTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 197
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A +H AA + +V L+ H A +T KK +T LH AA G + V LL
Sbjct: 198 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 257
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G ++ G TPLH+A Q V L++ GA + G TPLH AA
Sbjct: 258 LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL 317
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G TPLH+ A G +++ G
Sbjct: 318 CLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSG 359
Score = 114 bits (274), Expect = 4e-25
Identities = 73/221 (33%), Positives = 101/221 (45%), Gaps = 1/221 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + +++ LL G + TPLH+A G + L+ GA V
Sbjct: 238 TPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 297
Query: 196 ITADHYNPLHIAAKQ-HNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ PLH AA H L+ + A + +K G T LH+ A +G + ++
Sbjct: 298 KNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQ 357
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA D KNG TPLHIAA+Y + + TL+ GAD +G PLH+AA +
Sbjct: 358 SGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC 417
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + G T LH AA G+ E LLL G
Sbjct: 418 CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTG 458
Score = 114 bits (274), Expect = 4e-25
Identities = 75/222 (33%), Positives = 106/222 (47%), Gaps = 1/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHGAD 186
G TP+H+A ++ L+ GA V K + TPLH A+ + + + LL+ +GAD
Sbjct: 269 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGAD 328
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + D PLH+ A + +I+ A + K G T LH+AA+YG+ + N L
Sbjct: 329 VNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 388
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
+ GA + G +GM PLH+AA LL G D G T LH AA +
Sbjct: 389 ITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNL 448
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
E LL GA N + K G +PLH AA + + C L G
Sbjct: 449 ECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQ-CLFALVG 489
Score = 106 bits (254), Expect = 9e-23
Identities = 66/208 (31%), Positives = 100/208 (48%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D +R L+ V + E++TPLH A+ LG+ +I LL+ GA V A + PLH A
Sbjct: 52 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRA 111
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
+ + L++H+A + A K T LH+AA +K A L+ + + + + G
Sbjct: 112 VASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR 171
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T LH AA + LL +GA+ A K +H AA +E L+ +GA
Sbjct: 172 TALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTC 231
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ K +TPLH AA G + LL+ G
Sbjct: 232 KDKKSYTPLHAAASSGMISVVKYLLDLG 259
Score = 105 bits (253), Expect = 1e-22
Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+ A + ++++GA ++ + + TPLHIA+R G+ + L+ GAD
Sbjct: 336 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 395
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA D L+ + G T LH AA GNL+ NLLL
Sbjct: 396 AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 455
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN-QM 546
GA ++ K G +PLH AA L+ GA + + G TPLH AA +
Sbjct: 456 NTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG 515
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ LL A K G+ +H +A GH +C L+
Sbjct: 516 KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH-RLCLQLI 554
Score = 103 bits (247), Expect = 7e-22
Identities = 71/217 (32%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+H AA + H + + +L+ NGA V K+++ +TPLH+ + G + ++Q GA
Sbjct: 301 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 360
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLHIAA+ + + LI A G LHLAA G
Sbjct: 361 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 420
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL+ G D G T LH AA LL GAD K G +PLH AA
Sbjct: 421 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN 480
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
+ L+ GA N + G TPLH AA C
Sbjct: 481 YQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKC 517
Score = 91.9 bits (218), Expect = 2e-18
Identities = 74/237 (31%), Positives = 110/237 (46%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G P+HLAA + +D R LL +G ++ +T LH A+ GN++ LLL GA
Sbjct: 400 IHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 459
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-NLKVAN 360
D +PLH AA N+ AL+ A + ++G T LH AA + K
Sbjct: 460 DFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLE 519
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQ----QAVAT-----TLLE-KGADAKAVAKNGH 510
LL + A P K G +H +A Y Q +A+ L+E G D + + N
Sbjct: 520 YLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRA 579
Query: 511 T--PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T PLH+AA + L++ + + +G TPL LAA +GH E +L+ G
Sbjct: 580 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 636
Score = 77.4 bits (182), Expect = 5e-14
Identities = 57/178 (32%), Positives = 75/178 (42%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G+ D L+ DV + PLH AA + ++ LI A + A K T L
Sbjct: 49 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 108
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
H A + + +LL H A + KN TPLHIAA A L+ ++ +
Sbjct: 109 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 168
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA E LL GA NA K +H AA GH E+ LL+ G
Sbjct: 169 AGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 226
Score = 77.0 bits (181), Expect = 7e-14
Identities = 70/243 (28%), Positives = 108/243 (44%), Gaps = 20/243 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTD--IIRILLRNGAAVEAKARERQTPLHIASRLGN----------V 150
RG TP+H AA ++ TD + LLRN A + ++ +H ++ G+
Sbjct: 500 RGCTPLHYAATSD-TDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 558
Query: 151 DIAVLLLQHGADVRAITADH--YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALH 324
+ VL+ G D+ + + + +PLH+AA +H L++ L G T L
Sbjct: 559 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 618
Query: 325 LAAKYGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
LAA G+++ ++L+ GA+ D K TP+H AA L+ AV
Sbjct: 619 LAAFKGHVECVDVLINQGASILVKDYILKR--TPIHAAATNGHSECLRLLIGNAEPQNAV 676
Query: 496 A---KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
NG TPL ++ + +LL GA +A+ K G T LH A GH E LL
Sbjct: 677 DIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 736
Query: 667 EGG 675
+ G
Sbjct: 737 QHG 739
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/226 (27%), Positives = 98/226 (43%), Gaps = 4/226 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ ETP+ + + TD++ ++ R +PLH+A+ G+ +L+Q
Sbjct: 554 IASETPLDVLMETSGTDMLS---------DSDNRATISPLHLAAYHGHHQALEVLVQSLL 604
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTK-KGFTALHLAAKYGNLKVAN 360
D+ + PL +AA + + + LI A + T +H AA G+ +
Sbjct: 605 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 664
Query: 361 LLLAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
LL+ + A D NG TPL ++ +LL KGA+ A K G T LH A
Sbjct: 665 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 724
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
E LL++GA G TP+HL+A GH + LL+
Sbjct: 725 VTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 770
Score = 73.3 bits (172), Expect = 8e-13
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 4/165 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ LAA H + + +L+ GA++ K ++TP+H A+ G+ + LL+ +
Sbjct: 613 GRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEP 672
Query: 187 VRAITADHYN---PLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+ N PL ++ + D +L+ A + A K G TALH A G+ +
Sbjct: 673 QNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECV 732
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
+ LL HGA G TP+H++A V LL+ A A
Sbjct: 733 DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDA 777
Score = 72.5 bits (170), Expect = 1e-12
Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 6/198 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+HLAA H + +L+++ ++ + +TPL +A+ G+V+ +L+ GA +
Sbjct: 582 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-- 639
Query: 196 ITADHY---NPLHIAAKQHNHDVAAALIEHNAPLTATTKK---GFTALHLAAKYGNLKVA 357
+ D+ P+H AA + + LI + P A + G T L L+ G+
Sbjct: 640 LVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 699
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LL GA D K G T LH A + LL+ GA G TP+H++A
Sbjct: 700 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 759
Query: 538 NQMETAATLLEYGALTNA 591
+ LL+ A +A
Sbjct: 760 GHIGVLGALLQSAASMDA 777
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/30 (40%), Positives = 21/30 (70%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEA 96
RG TP+HL+A H ++ LL++ A+++A
Sbjct: 748 RGRTPIHLSAACGHIGVLGALLQSAASMDA 777
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 141 bits (342), Expect = 2e-33
Identities = 77/226 (34%), Positives = 119/226 (52%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++++LL GA + A ++ + +H A+ +G++++ LL+ HGA+V
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA V L++ + G T LH+A G V N L+
Sbjct: 233 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 292
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
GA +Q + G TPLH AA A+ LL GAD +K+G TPLH+ A +
Sbjct: 293 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRF 352
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ T+++ GA+ + E K G TPLH+AA+ GH + L+ G T
Sbjct: 353 SRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Score = 130 bits (314), Expect = 5e-30
Identities = 76/219 (34%), Positives = 112/219 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++LL++ A V A+ + QTPLHIA+ V A L+ ++V
Sbjct: 109 TPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 168
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK A+H AA G+++V LL++H
Sbjct: 169 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSH 228
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K TPLH AA +V LL+ G D G+TPLH+A Q
Sbjct: 229 GAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 288
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L++ GA+ N +++ GFTPLH AA H +C LL G
Sbjct: 289 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVG 327
Score = 118 bits (283), Expect = 3e-26
Identities = 75/220 (34%), Positives = 107/220 (48%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA +II +L+ +GA V AK + TPLH A + + +LL+H ADV A
Sbjct: 76 TPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNA 135
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLHIAA A AL+ + + + + G TALH AA G+ ++ LLL+
Sbjct: 136 RDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSR 195
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K +H AA V L+ GA+ K +TPLH AA +
Sbjct: 196 GANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVV 255
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ G N + G TPLH+A G + L++ G
Sbjct: 256 KYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 295
Score = 116 bits (278), Expect = 1e-25
Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA L+ + V R +T LH A+ G+ ++ LLL GA++
Sbjct: 141 QTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 200
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A +H AA + +V L+ H A +T KK +T LH AA G + V LL
Sbjct: 201 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 260
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G ++ G TPLH+A Q V L++ GA + G TPLH AA
Sbjct: 261 LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL 320
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G TPLH+ A G +++ G
Sbjct: 321 CLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSG 362
Score = 114 bits (274), Expect = 4e-25
Identities = 73/221 (33%), Positives = 101/221 (45%), Gaps = 1/221 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + +++ LL G + TPLH+A G + L+ GA V
Sbjct: 241 TPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 300
Query: 196 ITADHYNPLHIAAKQ-HNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ PLH AA H L+ + A + +K G T LH+ A +G + ++
Sbjct: 301 KNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQ 360
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA D KNG TPLHIAA+Y + + TL+ GAD +G PLH+AA +
Sbjct: 361 SGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC 420
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + G T LH AA G+ E LLL G
Sbjct: 421 CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTG 461
Score = 114 bits (274), Expect = 4e-25
Identities = 75/222 (33%), Positives = 106/222 (47%), Gaps = 1/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHGAD 186
G TP+H+A ++ L+ GA V K + TPLH A+ + + + LL+ +GAD
Sbjct: 272 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGAD 331
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + D PLH+ A + +I+ A + K G T LH+AA+YG+ + N L
Sbjct: 332 VNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 391
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
+ GA + G +GM PLH+AA LL G D G T LH AA +
Sbjct: 392 ITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNL 451
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
E LL GA N + K G +PLH AA + + C L G
Sbjct: 452 ECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQ-CLFALVG 492
Score = 106 bits (254), Expect = 9e-23
Identities = 66/208 (31%), Positives = 100/208 (48%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D +R L+ V + E++TPLH A+ LG+ +I LL+ GA V A + PLH A
Sbjct: 55 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRA 114
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
+ + L++H+A + A K T LH+AA +K A L+ + + + + G
Sbjct: 115 VASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR 174
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T LH AA + LL +GA+ A K +H AA +E L+ +GA
Sbjct: 175 TALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTC 234
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ K +TPLH AA G + LL+ G
Sbjct: 235 KDKKSYTPLHAAASSGMISVVKYLLDLG 262
Score = 105 bits (253), Expect = 1e-22
Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+ A + ++++GA ++ + + TPLHIA+R G+ + L+ GAD
Sbjct: 339 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA D L+ + G T LH AA GNL+ NLLL
Sbjct: 399 AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 458
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN-QM 546
GA ++ K G +PLH AA L+ GA + + G TPLH AA +
Sbjct: 459 NTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG 518
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ LL A K G+ +H +A GH +C L+
Sbjct: 519 KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH-RLCLQLI 557
Score = 103 bits (247), Expect = 7e-22
Identities = 71/217 (32%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+H AA + H + + +L+ NGA V K+++ +TPLH+ + G + ++Q GA
Sbjct: 304 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 363
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLHIAA+ + + LI A G LHLAA G
Sbjct: 364 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 423
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL+ G D G T LH AA LL GAD K G +PLH AA
Sbjct: 424 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN 483
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
+ L+ GA N + G TPLH AA C
Sbjct: 484 YQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKC 520
Score = 91.9 bits (218), Expect = 2e-18
Identities = 74/237 (31%), Positives = 110/237 (46%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G P+HLAA + +D R LL +G ++ +T LH A+ GN++ LLL GA
Sbjct: 403 IHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 462
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-NLKVAN 360
D +PLH AA N+ AL+ A + ++G T LH AA + K
Sbjct: 463 DFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLE 522
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQ----QAVAT-----TLLE-KGADAKAVAKNGH 510
LL + A P K G +H +A Y Q +A+ L+E G D + + N
Sbjct: 523 YLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRA 582
Query: 511 T--PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T PLH+AA + L++ + + +G TPL LAA +GH E +L+ G
Sbjct: 583 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 639
Score = 77.4 bits (182), Expect = 5e-14
Identities = 57/178 (32%), Positives = 75/178 (42%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G+ D L+ DV + PLH AA + ++ LI A + A K T L
Sbjct: 52 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 111
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
H A + + +LL H A + KN TPLHIAA A L+ ++ +
Sbjct: 112 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 171
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA E LL GA NA K +H AA GH E+ LL+ G
Sbjct: 172 AGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 229
Score = 77.0 bits (181), Expect = 7e-14
Identities = 70/243 (28%), Positives = 108/243 (44%), Gaps = 20/243 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTD--IIRILLRNGAAVEAKARERQTPLHIASRLGN----------V 150
RG TP+H AA ++ TD + LLRN A + ++ +H ++ G+
Sbjct: 503 RGCTPLHYAATSD-TDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 151 DIAVLLLQHGADVRAITADH--YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALH 324
+ VL+ G D+ + + + +PLH+AA +H L++ L G T L
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 621
Query: 325 LAAKYGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
LAA G+++ ++L+ GA+ D K TP+H AA L+ AV
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDYILKR--TPIHAAATNGHSECLRLLIGNAEPQNAV 679
Query: 496 A---KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
NG TPL ++ + +LL GA +A+ K G T LH A GH E LL
Sbjct: 680 DIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 739
Query: 667 EGG 675
+ G
Sbjct: 740 QHG 742
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/226 (27%), Positives = 98/226 (43%), Gaps = 4/226 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ ETP+ + + TD++ ++ R +PLH+A+ G+ +L+Q
Sbjct: 557 IASETPLDVLMETSGTDMLS---------DSDNRATISPLHLAAYHGHHQALEVLVQSLL 607
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTK-KGFTALHLAAKYGNLKVAN 360
D+ + PL +AA + + + LI A + T +H AA G+ +
Sbjct: 608 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 667
Query: 361 LLLAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
LL+ + A D NG TPL ++ +LL KGA+ A K G T LH A
Sbjct: 668 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 727
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
E LL++GA G TP+HL+A GH + LL+
Sbjct: 728 VTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 773
Score = 73.3 bits (172), Expect = 8e-13
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 4/165 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ LAA H + + +L+ GA++ K ++TP+H A+ G+ + LL+ +
Sbjct: 616 GRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEP 675
Query: 187 VRAITADHYN---PLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+ N PL ++ + D +L+ A + A K G TALH A G+ +
Sbjct: 676 QNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECV 735
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
+ LL HGA G TP+H++A V LL+ A A
Sbjct: 736 DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDA 780
Score = 72.5 bits (170), Expect = 1e-12
Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 6/198 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+HLAA H + +L+++ ++ + +TPL +A+ G+V+ +L+ GA +
Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-- 642
Query: 196 ITADHY---NPLHIAAKQHNHDVAAALIEHNAPLTATTKK---GFTALHLAAKYGNLKVA 357
+ D+ P+H AA + + LI + P A + G T L L+ G+
Sbjct: 643 LVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 702
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LL GA D K G T LH A + LL+ GA G TP+H++A
Sbjct: 703 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 762
Query: 538 NQMETAATLLEYGALTNA 591
+ LL+ A +A
Sbjct: 763 GHIGVLGALLQSAASMDA 780
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/30 (40%), Positives = 21/30 (70%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEA 96
RG TP+HL+A H ++ LL++ A+++A
Sbjct: 751 RGRTPIHLSAACGHIGVLGALLQSAASMDA 780
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 141 bits (342), Expect = 2e-33
Identities = 77/226 (34%), Positives = 119/226 (52%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++++LL GA + A ++ + +H A+ +G++++ LL+ HGA+V
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA V L++ + G T LH+A G V N L+
Sbjct: 233 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 292
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
GA +Q + G TPLH AA A+ LL GAD +K+G TPLH+ A +
Sbjct: 293 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRF 352
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ T+++ GA+ + E K G TPLH+AA+ GH + L+ G T
Sbjct: 353 SRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Score = 130 bits (314), Expect = 5e-30
Identities = 76/219 (34%), Positives = 112/219 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++LL++ A V A+ + QTPLHIA+ V A L+ ++V
Sbjct: 109 TPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 168
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK A+H AA G+++V LL++H
Sbjct: 169 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSH 228
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K TPLH AA +V LL+ G D G+TPLH+A Q
Sbjct: 229 GAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 288
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L++ GA+ N +++ GFTPLH AA H +C LL G
Sbjct: 289 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVG 327
Score = 118 bits (283), Expect = 3e-26
Identities = 75/220 (34%), Positives = 107/220 (48%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA +II +L+ +GA V AK + TPLH A + + +LL+H ADV A
Sbjct: 76 TPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNA 135
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLHIAA A AL+ + + + + G TALH AA G+ ++ LLL+
Sbjct: 136 RDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSR 195
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K +H AA V L+ GA+ K +TPLH AA +
Sbjct: 196 GANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVV 255
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ G N + G TPLH+A G + L++ G
Sbjct: 256 KYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 295
Score = 116 bits (278), Expect = 1e-25
Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA L+ + V R +T LH A+ G+ ++ LLL GA++
Sbjct: 141 QTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 200
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A +H AA + +V L+ H A +T KK +T LH AA G + V LL
Sbjct: 201 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 260
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G ++ G TPLH+A Q V L++ GA + G TPLH AA
Sbjct: 261 LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL 320
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G TPLH+ A G +++ G
Sbjct: 321 CLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSG 362
Score = 114 bits (274), Expect = 4e-25
Identities = 73/221 (33%), Positives = 101/221 (45%), Gaps = 1/221 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + +++ LL G + TPLH+A G + L+ GA V
Sbjct: 241 TPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 300
Query: 196 ITADHYNPLHIAAKQ-HNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ PLH AA H L+ + A + +K G T LH+ A +G + ++
Sbjct: 301 KNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQ 360
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA D KNG TPLHIAA+Y + + TL+ GAD +G PLH+AA +
Sbjct: 361 SGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC 420
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + G T LH AA G+ E LLL G
Sbjct: 421 CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTG 461
Score = 114 bits (274), Expect = 4e-25
Identities = 75/222 (33%), Positives = 106/222 (47%), Gaps = 1/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHGAD 186
G TP+H+A ++ L+ GA V K + TPLH A+ + + + LL+ +GAD
Sbjct: 272 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGAD 331
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + D PLH+ A + +I+ A + K G T LH+AA+YG+ + N L
Sbjct: 332 VNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 391
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
+ GA + G +GM PLH+AA LL G D G T LH AA +
Sbjct: 392 ITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNL 451
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
E LL GA N + K G +PLH AA + + C L G
Sbjct: 452 ECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQ-CLFALVG 492
Score = 106 bits (254), Expect = 9e-23
Identities = 66/208 (31%), Positives = 100/208 (48%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D +R L+ V + E++TPLH A+ LG+ +I LL+ GA V A + PLH A
Sbjct: 55 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRA 114
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
+ + L++H+A + A K T LH+AA +K A L+ + + + + G
Sbjct: 115 VASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR 174
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T LH AA + LL +GA+ A K +H AA +E L+ +GA
Sbjct: 175 TALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTC 234
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ K +TPLH AA G + LL+ G
Sbjct: 235 KDKKSYTPLHAAASSGMISVVKYLLDLG 262
Score = 106 bits (254), Expect = 9e-23
Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+ A + ++++GA ++ + + TPLHIA+R G+ + L+ GAD
Sbjct: 339 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA D L+ + G T LH AA GNL+ NLLL
Sbjct: 399 AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 458
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN-QM 546
GA ++ K G +PLH AA L+ GA + + G TPLH AA +
Sbjct: 459 NTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG 518
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ LL A K G+ +H +A GH +C L+
Sbjct: 519 KCLEYLLRNDANPGVRDKQGYNAVHYSAAYGH-RLCLQLI 557
Score = 103 bits (247), Expect = 7e-22
Identities = 71/217 (32%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+H AA + H + + +L+ NGA V K+++ +TPLH+ + G + ++Q GA
Sbjct: 304 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 363
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLHIAA+ + + LI A G LHLAA G
Sbjct: 364 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 423
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL+ G D G T LH AA LL GAD K G +PLH AA
Sbjct: 424 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN 483
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
+ L+ GA N + G TPLH AA C
Sbjct: 484 YQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKC 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 74/237 (31%), Positives = 110/237 (46%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G P+HLAA + +D R LL +G ++ +T LH A+ GN++ LLL GA
Sbjct: 403 IHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 462
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-NLKVAN 360
D +PLH AA N+ AL+ A + ++G T LH AA + K
Sbjct: 463 DFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLE 522
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQ----QAVAT-----TLLE-KGADAKAVAKNGH 510
LL + A P K G +H +A Y Q +A+ L+E G D + + N
Sbjct: 523 YLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRA 582
Query: 511 T--PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T PLH+AA + L++ + + +G TPL LAA +GH E +L+ G
Sbjct: 583 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 639
Score = 86.2 bits (204), Expect = 1e-16
Identities = 67/243 (27%), Positives = 104/243 (42%), Gaps = 14/243 (5%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + + + +LL GA K + ++PLH A+ N L+ GA V
Sbjct: 438 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 497
Query: 190 RAITADHYNPLHIAAKQHNHDVAAA-LIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ PLH AA L+ ++A K+G+ A+H +A YG+ L+
Sbjct: 498 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLI 557
Query: 367 LAH------------GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
+ D + ++PLH+AA + L++ D +G
Sbjct: 558 ASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGR 617
Query: 511 TPLHIAARKNQMETAATLLEYGA-LTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
TPL +AA K +E L+ GA + + TP+H AA GH+E C LL G Q
Sbjct: 618 TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSE-CLRLLIGNAEPQ 676
Query: 688 FAL 696
A+
Sbjct: 677 NAV 679
Score = 77.4 bits (182), Expect = 5e-14
Identities = 57/178 (32%), Positives = 75/178 (42%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G+ D L+ DV + PLH AA + ++ LI A + A K T L
Sbjct: 52 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 111
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
H A + + +LL H A + KN TPLHIAA A L+ ++ +
Sbjct: 112 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 171
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA E LL GA NA K +H AA GH E+ LL+ G
Sbjct: 172 AGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 229
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 141 bits (342), Expect = 2e-33
Identities = 77/226 (34%), Positives = 119/226 (52%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++++LL GA + A ++ + +H A+ +G++++ LL+ HGA+V
Sbjct: 146 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 205
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA V L++ + G T LH+A G V N L+
Sbjct: 206 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 265
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
GA +Q + G TPLH AA A+ LL GAD +K+G TPLH+ A +
Sbjct: 266 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRF 325
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ T+++ GA+ + E K G TPLH+AA+ GH + L+ G T
Sbjct: 326 SRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 371
Score = 130 bits (314), Expect = 5e-30
Identities = 76/219 (34%), Positives = 112/219 (51%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++LL++ A V A+ + QTPLHIA+ V A L+ ++V
Sbjct: 82 TPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 141
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK A+H AA G+++V LL++H
Sbjct: 142 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSH 201
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K TPLH AA +V LL+ G D G+TPLH+A Q
Sbjct: 202 GAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 261
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L++ GA+ N +++ GFTPLH AA H +C LL G
Sbjct: 262 NELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVG 300
Score = 118 bits (283), Expect = 3e-26
Identities = 75/220 (34%), Positives = 107/220 (48%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA +II +L+ +GA V AK + TPLH A + + +LL+H ADV A
Sbjct: 49 TPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNA 108
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLHIAA A AL+ + + + + G TALH AA G+ ++ LLL+
Sbjct: 109 RDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSR 168
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K +H AA V L+ GA+ K +TPLH AA +
Sbjct: 169 GANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVV 228
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL+ G N + G TPLH+A G + L++ G
Sbjct: 229 KYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 268
Score = 116 bits (278), Expect = 1e-25
Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA L+ + V R +T LH A+ G+ ++ LLL GA++
Sbjct: 114 QTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 173
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A +H AA + +V L+ H A +T KK +T LH AA G + V LL
Sbjct: 174 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 233
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G ++ G TPLH+A Q V L++ GA + G TPLH AA
Sbjct: 234 LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL 293
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G TPLH+ A G +++ G
Sbjct: 294 CLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSG 335
Score = 114 bits (274), Expect = 4e-25
Identities = 73/221 (33%), Positives = 101/221 (45%), Gaps = 1/221 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + +++ LL G + TPLH+A G + L+ GA V
Sbjct: 214 TPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 273
Query: 196 ITADHYNPLHIAAKQ-HNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ PLH AA H L+ + A + +K G T LH+ A +G + ++
Sbjct: 274 KNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQ 333
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA D KNG TPLHIAA+Y + + TL+ GAD +G PLH+AA +
Sbjct: 334 SGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC 393
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + G T LH AA G+ E LLL G
Sbjct: 394 CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTG 434
Score = 114 bits (274), Expect = 4e-25
Identities = 75/222 (33%), Positives = 106/222 (47%), Gaps = 1/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHGAD 186
G TP+H+A ++ L+ GA V K + TPLH A+ + + + LL+ +GAD
Sbjct: 245 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGAD 304
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + D PLH+ A + +I+ A + K G T LH+AA+YG+ + N L
Sbjct: 305 VNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 364
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
+ GA + G +GM PLH+AA LL G D G T LH AA +
Sbjct: 365 ITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNL 424
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
E LL GA N + K G +PLH AA + + C L G
Sbjct: 425 ECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQ-CLFALVG 465
Score = 110 bits (265), Expect = 4e-24
Identities = 75/225 (33%), Positives = 107/225 (47%), Gaps = 6/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+ L+ HTD + LL GA V+AK + +T LH + G+ + LLQHGA
Sbjct: 659 GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC 718
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA----TTKKGFTALHLAAKYGNLKVA 357
+ P+H++A + V AL++ A + A G+TALH A G+
Sbjct: 719 LLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCV 778
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GAD-AKAVAKNGHTPLHIAA 531
LLL G N +PLH A D + A L++ GA A G TPLH AA
Sbjct: 779 ELLLEQEVFQKTEG-NAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAA 837
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ +E LL + A N+ G TPL +AA+ G T +L+
Sbjct: 838 FTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLV 882
Score = 106 bits (254), Expect = 9e-23
Identities = 66/208 (31%), Positives = 100/208 (48%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D +R L+ V + E++TPLH A+ LG+ +I LL+ GA V A + PLH A
Sbjct: 28 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRA 87
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
+ + L++H+A + A K T LH+AA +K A L+ + + + + G
Sbjct: 88 VASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR 147
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T LH AA + LL +GA+ A K +H AA +E L+ +GA
Sbjct: 148 TALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTC 207
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ K +TPLH AA G + LL+ G
Sbjct: 208 KDKKSYTPLHAAASSGMISVVKYLLDLG 235
Score = 105 bits (253), Expect = 1e-22
Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+H+ A + ++++GA ++ + + TPLHIA+R G+ + L+ GAD
Sbjct: 312 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 371
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA D L+ + G T LH AA GNL+ NLLL
Sbjct: 372 AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 431
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN-QM 546
GA ++ K G +PLH AA L+ GA + + G TPLH AA +
Sbjct: 432 NTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDG 491
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ LL A K G+ +H +A GH +C L+
Sbjct: 492 KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH-RLCLQLI 530
Score = 103 bits (247), Expect = 7e-22
Identities = 71/217 (32%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+H AA + H + + +L+ NGA V K+++ +TPLH+ + G + ++Q GA
Sbjct: 277 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 336
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLHIAA+ + + LI A G LHLAA G
Sbjct: 337 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 396
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL+ G D G T LH AA LL GAD K G +PLH AA
Sbjct: 397 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN 456
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
+ L+ GA N + G TPLH AA C
Sbjct: 457 YQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKC 493
Score = 99.5 bits (237), Expect = 1e-20
Identities = 74/226 (32%), Positives = 104/226 (46%), Gaps = 9/226 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGA---AVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
TP+H AA H++ +R+L+ N AV+ + QTPL ++ G+ D LL GA+
Sbjct: 625 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 684
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A LH A + + AL++H A +G T +HL+A G++ V L
Sbjct: 685 VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGAL 744
Query: 367 LAHGAA----PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
L A+ P A +G T LH A + LLE+ K N +PLH A
Sbjct: 745 LQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEG-NAFSPLHCAVI 803
Query: 535 KNQMETAATLLE-YGA-LTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ A L++ GA + NA G TPLH AA H E LLL
Sbjct: 804 NDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLL 849
Score = 97.1 bits (231), Expect = 6e-20
Identities = 74/233 (31%), Positives = 109/233 (46%), Gaps = 10/233 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ----TPLHIASRLGNVDIAVLLLQ 174
RG TP+HL+A H ++ LL++ A+++A T LH A G+ LLL+
Sbjct: 724 RGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLE 783
Query: 175 HGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP--LTATTKKGFTALHLAAKYGNL 348
+ + ++PLH A N A LI+ + AT KG T LH AA ++
Sbjct: 784 QEV-FQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHV 842
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG-HTPLHI 525
+ LLL+H A + G TPL +AA+ Q L+ + + N +T LH+
Sbjct: 843 ECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHL 902
Query: 526 AARKNQMETAATLLEY---GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A K +A +LE L NA + A TPLH+AA+ G T + LL G
Sbjct: 903 ACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKG 955
Score = 91.9 bits (218), Expect = 2e-18
Identities = 74/237 (31%), Positives = 110/237 (46%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G P+HLAA + +D R LL +G ++ +T LH A+ GN++ LLL GA
Sbjct: 376 IHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 435
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG-NLKVAN 360
D +PLH AA N+ AL+ A + ++G T LH AA + K
Sbjct: 436 DFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLE 495
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQ----QAVAT-----TLLE-KGADAKAVAKNGH 510
LL + A P K G +H +A Y Q +A+ L+E G D + + N
Sbjct: 496 YLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRA 555
Query: 511 T--PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T PLH+AA + L++ + + +G TPL LAA +GH E +L+ G
Sbjct: 556 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 612
Score = 77.4 bits (182), Expect = 5e-14
Identities = 57/178 (32%), Positives = 75/178 (42%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G+ D L+ DV + PLH AA + ++ LI A + A K T L
Sbjct: 25 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 84
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
H A + + +LL H A + KN TPLHIAA A L+ ++ +
Sbjct: 85 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 144
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA E LL GA NA K +H AA GH E+ LL+ G
Sbjct: 145 AGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 202
Score = 77.0 bits (181), Expect = 7e-14
Identities = 70/243 (28%), Positives = 108/243 (44%), Gaps = 20/243 (8%)
Frame = +1
Query: 7 RGETPVHLAARANHTD--IIRILLRNGAAVEAKARERQTPLHIASRLGN----------V 150
RG TP+H AA ++ TD + LLRN A + ++ +H ++ G+
Sbjct: 476 RGCTPLHYAATSD-TDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 534
Query: 151 DIAVLLLQHGADVRAITADH--YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALH 324
+ VL+ G D+ + + + +PLH+AA +H L++ L G T L
Sbjct: 535 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 594
Query: 325 LAAKYGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
LAA G+++ ++L+ GA+ D K TP+H AA L+ AV
Sbjct: 595 LAAFKGHVECVDVLINQGASILVKDYILKR--TPIHAAATNGHSECLRLLIGNAEPQNAV 652
Query: 496 A---KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
NG TPL ++ + +LL GA +A+ K G T LH A GH E LL
Sbjct: 653 DIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 712
Query: 667 EGG 675
+ G
Sbjct: 713 QHG 715
Score = 76.6 bits (180), Expect = 9e-14
Identities = 65/225 (28%), Positives = 93/225 (41%), Gaps = 6/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH-GAD 186
G T +H A H + +LL + + +PLH A N A +L+ GA
Sbjct: 762 GYTALHWACYNGHETCVELLLEQEVFQKTEGNAF-SPLHCAVINDNEGAAEMLIDTLGAS 820
Query: 187 -VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A + PLH AA + + L+ HNA + + G T L +AA+ G +
Sbjct: 821 IVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEM 880
Query: 364 LLAHGAAPDQAGKNGM-TPLHIAAQYDQQAVATTLLEKGADAKAV-AKNG--HTPLHIAA 531
L++ +A N T LH+A + A +LEK D + A N TPLH+AA
Sbjct: 881 LVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAA 940
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
R LL GA A + G+TP A C L+
Sbjct: 941 RNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALI 985
Score = 75.4 bits (177), Expect = 2e-13
Identities = 61/191 (31%), Positives = 91/191 (47%), Gaps = 7/191 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRN-GAA-VEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
+P+H A ++ +L+ GA+ V A + +TPLH A+ +V+ LLL H A V
Sbjct: 796 SPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQV 855
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLL 366
++ + PL +AA+ + L+ +A LT TALHLA G+ A L+
Sbjct: 856 NSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLI 915
Query: 367 LAHGAAPDQAGKNG---MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP-LHIAAR 534
L + TPLH+AA+ V LL KGA AV +NG+TP L A
Sbjct: 916 LEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPN 975
Query: 535 KNQMETAATLL 567
K+ + A +L
Sbjct: 976 KDVADCLALIL 986
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/226 (27%), Positives = 98/226 (43%), Gaps = 4/226 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ ETP+ + + TD++ ++ R +PLH+A+ G+ +L+Q
Sbjct: 530 IASETPLDVLMETSGTDMLS---------DSDNRATISPLHLAAYHGHHQALEVLVQSLL 580
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTK-KGFTALHLAAKYGNLKVAN 360
D+ + PL +AA + + + LI A + T +H AA G+ +
Sbjct: 581 DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLR 640
Query: 361 LLLAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
LL+ + A D NG TPL ++ +LL KGA+ A K G T LH A
Sbjct: 641 LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGA 700
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
E LL++GA G TP+HL+A GH + LL+
Sbjct: 701 VTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 746
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 140 bits (339), Expect = 5e-33
Identities = 79/226 (34%), Positives = 115/226 (50%), Gaps = 1/226 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA H +++ +LL GA + A ++ + LH A+ +G++D+ LL+ HGA+V
Sbjct: 115 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 174
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y PLH AA +V L+ + G TALH+A G V N L+
Sbjct: 175 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 234
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL-EKGADAKAVAKNGHTPLHIAARKNQM 546
+GA +Q NG TPLH AA A+ LL GAD +K+G +PLH+ A +
Sbjct: 235 DYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRF 294
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ TL++ G + K G TPLH+AA+ GH + L G T
Sbjct: 295 TRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADT 340
Score = 130 bits (315), Expect = 4e-30
Identities = 80/222 (36%), Positives = 108/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA +++ ++V R +T LH A+ G+V++ LLL GA++
Sbjct: 83 QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANIN 142
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A LH AA + DV A LI H A +T KKG+T LH AA G + V LL
Sbjct: 143 AFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLN 202
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G D+ G T LHIA Q AV L++ GA+ NG TPLH AA
Sbjct: 203 LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL 262
Query: 553 AATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA N +SK G +PLH+ A G L++ G
Sbjct: 263 CLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNG 304
Score = 126 bits (305), Expect = 6e-29
Identities = 76/217 (35%), Positives = 107/217 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H A + + +++L+++ A V A+ + QTPLH+A+ V A +++ + V
Sbjct: 51 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 110
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
LH AA + ++ L+ A + A KK ALH AA G+L V LL+ H
Sbjct: 111 SDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINH 170
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA K G TPLH AA Q V LL G + + G+T LHIA Q
Sbjct: 171 GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 230
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L++YGA N + GFTPLH AA H +C LL
Sbjct: 231 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELL 267
Score = 120 bits (289), Expect = 5e-27
Identities = 75/220 (34%), Positives = 108/220 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA +II +L+ +GA V AK TPLH A + + +L++H ADV A
Sbjct: 18 TPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNA 77
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA A +I + + + + G TALH AA G++++ NLLLA
Sbjct: 78 RDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAK 137
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GA + K LH AA V L+ GA+ K G+TPLH AA Q+
Sbjct: 138 GANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVV 197
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL G + + G T LH+A G + L++ G
Sbjct: 198 KHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG 237
Score = 114 bits (274), Expect = 4e-25
Identities = 70/224 (31%), Positives = 104/224 (46%), Gaps = 1/224 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G TP+H AA ++++ LL G ++ T LHIA G + L+ +GA+
Sbjct: 180 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 239
Query: 187 VRAITADHYNPLHI-AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V + + PLH AA H L+ + A + +K G + LH+ A +G +
Sbjct: 240 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 299
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
L+ +G D K+G TPLH+AA+Y + + TL GAD + PLH+AA
Sbjct: 300 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAH 359
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL G + K G T LH AA G+ E LL G
Sbjct: 360 SDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSG 403
Score = 111 bits (268), Expect = 2e-24
Identities = 67/204 (32%), Positives = 100/204 (49%)
Frame = +1
Query: 64 ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
+L+ V E++TPLH+A+ LG+ +I LL+ GA V A PLH A
Sbjct: 1 MLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASR 60
Query: 244 NHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLH 423
+ + LI+H+A + A K T LH+AA +K A +++ ++ + + + G T LH
Sbjct: 61 SEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALH 120
Query: 424 IAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKA 603
AA + LL KGA+ A K LH AA ++ A L+ +GA + K
Sbjct: 121 HAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKK 180
Query: 604 GFTPLHLAAQQGHTEMCALLLEGG 675
G+TPLH AA G + LL G
Sbjct: 181 GYTPLHAAASNGQINVVKHLLNLG 204
Score = 108 bits (260), Expect = 2e-23
Identities = 72/225 (32%), Positives = 102/225 (45%), Gaps = 1/225 (0%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAV-LLLQHG 180
V G T +H+A ++ L+ GA V TPLH A+ + + + LL+ +G
Sbjct: 212 VYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNG 271
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
ADV + D +PLH+ A + LI++ + K G T LH+AA+YG+ + N
Sbjct: 272 ADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLIN 331
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L GA + G + M PLH+AA LL G + K G T LH AA
Sbjct: 332 TLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGG 391
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E L GA + + K G TPLH AA H L+ G
Sbjct: 392 NVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTG 436
Score = 99.1 bits (236), Expect = 1e-20
Identities = 67/209 (32%), Positives = 97/209 (46%), Gaps = 2/209 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDI-IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+H AA + H + + +L+ NGA V ++++ ++PLH+ + G + L+Q+G +
Sbjct: 247 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 306
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTK-KGFTALHLAAKYGNLKVANL 363
+ + D PLH+AA+ + H++ + + TA LHLAA +
Sbjct: 307 IDCVDKDGNTPLHVAAR-YGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRK 365
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL+ G D K G T LH AA L GAD K G TPLH AA
Sbjct: 366 LLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCH 425
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAA 630
TL+ GA N G T LH AA
Sbjct: 426 FHCIETLVTTGANVNETDDWGRTALHYAA 454
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/186 (31%), Positives = 87/186 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G++P+H+ A + L++NG ++ ++ TPLH+A+R G+ + L GAD
Sbjct: 281 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADT 340
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+AA + D L+ + K G T LH AA GN++ LL
Sbjct: 341 AKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQ 400
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ GA + K G TPLH AA TL+ GA+ G T LH AA + M+
Sbjct: 401 SSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAA-ASDMD 459
Query: 550 TAATLL 567
T+L
Sbjct: 460 RNKTIL 465
Score = 85.0 bits (201), Expect = 3e-16
Identities = 68/229 (29%), Positives = 97/229 (42%), Gaps = 8/229 (3%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLR---NGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
V TP+H + HT +R+LL N AV+ K + QTPL +A G++D LLL+
Sbjct: 607 VTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLE 666
Query: 175 HGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKV 354
A+V + LH + + L+E + +G T LH AA G+
Sbjct: 667 KEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATW 726
Query: 355 ANLLLAHGAAPDQA---GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+ LL + + G TPLH A + LLE+ K + N TPLH
Sbjct: 727 LSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIG-NPFTPLHC 785
Query: 526 AARKNQMETAATLLEY--GALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A + A+ LL ++ + G TPL AA H E LLL
Sbjct: 786 AIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLL 834
Score = 79.4 bits (187), Expect = 1e-14
Identities = 65/228 (28%), Positives = 100/228 (43%), Gaps = 9/228 (3%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
++P+HLAA H + +LL++ ++ + + +T L +A+ G+ + L+ GA +
Sbjct: 543 KSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASIF 602
Query: 193 AI-TADHYNPLHIAAKQHNHDVAAALIEHNA--PLTATTK--KGFTALHLAAKYGNLKVA 357
PLH A+ + H + L+ A P K KG T L LA YG++
Sbjct: 603 VKDNVTKRTPLH-ASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAV 661
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLL A D G T LH + LLE+ G TPLH AA +
Sbjct: 662 SLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAAR 721
Query: 538 NQMETAATLLEYGALTNAE----SKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL+ AL+ + G+TPLH A G+ +LLE
Sbjct: 722 GHATWLSELLQM-ALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLE 768
Score = 76.6 bits (180), Expect = 9e-14
Identities = 68/227 (29%), Positives = 93/227 (40%), Gaps = 6/227 (2%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+ G T +H H + +++LL ++ K +TPLH A+ G+ LLQ
Sbjct: 676 ILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMAL 735
Query: 181 ADVRAITADH--YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKV 354
++ D+ Y PLH A N + L+E FT LH A +
Sbjct: 736 SEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKC-FRKFIGNPFTPLHCAIINDHGNC 794
Query: 355 ANLLLA--HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
A+LLL + G TPL AA D LL A AV +G T L +A
Sbjct: 795 ASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMA 854
Query: 529 ARKNQMETAATLLEYG-ALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A Q L+ A + K TPLHLA +GH E CALL+
Sbjct: 855 AENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGH-EKCALLI 900
Score = 76.2 bits (179), Expect = 1e-13
Identities = 67/228 (29%), Positives = 94/228 (41%), Gaps = 8/228 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLR--NGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
G +H AA H + +LL N E+ + ++PLH+A+ G+ +LLQ
Sbjct: 507 GYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLV 566
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA---TTKKGFTALHLAAKYGNLKV 354
D+ L +AA + + + ALI A + TK+ T LH + G+
Sbjct: 567 DLDIRDEKGRTALDLAAFKGHTECVEALINPGASIFVKDNVTKR--TPLHASVINGHTLC 624
Query: 355 ANLLLAHGAAP---DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
LLL P D G TPL +A Y + LLEK A+ V G T LH
Sbjct: 625 LRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHR 684
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
E LLE + G TPLH AA +GH + LL+
Sbjct: 685 GIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQ 732
Score = 76.2 bits (179), Expect = 1e-13
Identities = 65/227 (28%), Positives = 92/227 (40%), Gaps = 7/227 (3%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGA 183
+G T + LAA HT+ + L+ GA++ K ++TPLH + G+ LLL+
Sbjct: 574 KGRTALDLAAFKGHTECVEALINPGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIAD 633
Query: 184 DVRAI---TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKV 354
+ A+ A PL +A + D + L+E A + G TALH G+ +
Sbjct: 634 NPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEEC 693
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG---ADAKAVAKNGHTPLHI 525
+LL + G TPLH AA + LL+ D G+TPLH
Sbjct: 694 VQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHW 753
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LLE FTPLH A H +LLL
Sbjct: 754 ACYNGNENCIEVLLEQKCFRKFIGNP-FTPLHCAIINDHGNCASLLL 799
Score = 74.9 bits (176), Expect = 3e-13
Identities = 64/226 (28%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G+TP+ LA H D + +LL A V+ T LH G+ + +LL+
Sbjct: 644 KGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVS 703
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIE---HNAPLTATTKKGFTALHLAAKYGNLKVA 357
+ + PLH AA + + + L++ +G+T LH A GN
Sbjct: 704 ILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCI 763
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIA 528
+LL G N TPLH A D A+ LL D+ V+ G TPL A
Sbjct: 764 EVLLEQKCFRKFIG-NPFTPLHCAIINDHGNCASLLL-GAIDSSIVSCRDDKGRTPLRAA 821
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A + +E LL + A NA +G T L +AA+ G +L+
Sbjct: 822 AFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILV 867
Score = 74.1 bits (174), Expect = 5e-13
Identities = 76/249 (30%), Positives = 102/249 (40%), Gaps = 30/249 (12%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+HLAA H+D R LL +G ++ + +T LH A+ GNV+ LL GAD
Sbjct: 350 PLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKK 409
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL-HLAAK--------YGNL- 348
PLH AA + L+ A + T G TAL + AA GN
Sbjct: 410 DKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAH 469
Query: 349 --------------KVANL----LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
K A L LL + A P K G +H AA Y + LLE+
Sbjct: 470 DNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLER 529
Query: 475 GADAKAVAKNGHT--PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTE 648
+ +G T PLH+AA + LL+ + + G T L LAA +GHTE
Sbjct: 530 TNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTE 589
Query: 649 MCALLLEGG 675
L+ G
Sbjct: 590 CVEALINPG 598
Score = 73.3 bits (172), Expect = 8e-13
Identities = 57/194 (29%), Positives = 89/194 (45%), Gaps = 6/194 (3%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEA---KARERQTPLHIASRLGNVDIAVLLLQH 177
RG TP+H AA H + LL+ + E K + TPLH A GN + +LL+
Sbjct: 710 RGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQ 769
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIE--HNAPLTATTKKGFTALHLAAKYGNLK 351
R + + PLH A + + A+ L+ ++ ++ KG T L AA +++
Sbjct: 770 KC-FRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVE 828
Query: 352 VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIA 528
LLL H A + +G T L +AA+ Q L+ AD K+ +TPLH+A
Sbjct: 829 CLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLA 888
Query: 529 ARKNQMETAATLLE 570
K + A +L+
Sbjct: 889 CSKGHEKCALLILD 902
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/166 (27%), Positives = 72/166 (43%), Gaps = 3/166 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH-GA 183
+G TP+H A + + I +LL TPLH A + + A LLL +
Sbjct: 746 QGYTPLHWACYNGNENCIEVLLEQ-KCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDS 804
Query: 184 DVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + D PL AA + + L+ H+AP+ A G TAL +AA+ G +
Sbjct: 805 SIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVD 864
Query: 361 LLLAHGAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+L+ A K+ TPLH+A + A +L+K D +
Sbjct: 865 ILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLI 910
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 131 bits (316), Expect = 3e-30
Identities = 84/228 (36%), Positives = 116/228 (50%), Gaps = 5/228 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + AA H DI+ LL++GA V E +T L A+ +G+ +I LL HGA+V
Sbjct: 497 TALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNH 556
Query: 196 ITADHYNPLHIAA-----KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D L +AA + + V + LI+ A + K G T L +AA G++ V +
Sbjct: 557 EDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVD 616
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D NG TPL AA +V TLL GA ++ G T L IA+ +
Sbjct: 617 LLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQG 676
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+E TLL+ G N AG+TPLH+AA +GH +C L+E G T
Sbjct: 677 NVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 724
Score = 118 bits (285), Expect = 2e-26
Identities = 74/219 (33%), Positives = 105/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++ LL GAAV++ E +T L IAS GNV++ LL G D
Sbjct: 632 GRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 691
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH+AA + + + ALIE A G LA++ G+ +LL
Sbjct: 692 NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILL 751
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ + DQ G +G L +AA + + L GAD +G L+I A +NQ+
Sbjct: 752 ENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLT 811
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LE GA A G T LH++ QGH EM +L+
Sbjct: 812 MAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 850
Score = 118 bits (285), Expect = 2e-26
Identities = 70/222 (31%), Positives = 117/222 (52%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P LA++ H D ++ILL N + ++ + + + L +A+ G+ DI LL HGADV
Sbjct: 731 GRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADV 790
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
AD L+I A ++ +A +E+ A + A+ +G TALH++ G++++ +L+
Sbjct: 791 NCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 850
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A+ A + A + L AA V L+E GA G T L IAA++ ++
Sbjct: 851 AYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHID 910
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LLE+GA N + G T + +AA+ GH+++ LL + G
Sbjct: 911 VVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYG 952
Score = 117 bits (282), Expect = 4e-26
Identities = 79/225 (35%), Positives = 108/225 (48%), Gaps = 5/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRL-----GNVDIAVLLLQ 174
G T + AA H +I+ LL +GA V + + +T L +A+ G+ + LL+
Sbjct: 528 GRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLID 587
Query: 175 HGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKV 354
GA+V D PL +AA + + DV L+E A + T G T L AA G+ V
Sbjct: 588 RGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASV 647
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
N LL GAA D G T L IA+ V TLL++G D G TPLH+AA
Sbjct: 648 VNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF 707
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E GA TN G P LA+Q+GH + +LLE
Sbjct: 708 EGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 752
Score = 108 bits (259), Expect = 2e-23
Identities = 67/222 (30%), Positives = 109/222 (49%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A+ + +++R LL G + TPLH+A+ G+ I L++ GA
Sbjct: 665 GRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 724
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I D P +A+++ ++D L+E+ + + G AL +AA G+ + LL
Sbjct: 725 NEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLF 784
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+HGA + +G L+I A +Q +A LE GA+ +A G T LH++ + ME
Sbjct: 785 SHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHME 844
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ Y A NA + L AA QGH ++ LL+E G
Sbjct: 845 MVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHG 886
Score = 106 bits (254), Expect = 9e-23
Identities = 63/214 (29%), Positives = 104/214 (48%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A H ++ +L+ GA V+ ++ TPL +A+ G+VD+ LLL+ GADV +
Sbjct: 574 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 633
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
PL AA + V L+ A + + +G T L +A+ GN++V LL G +
Sbjct: 634 TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 693
Query: 394 AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEY 573
G TPLH+AA + + L+E+GA + +G P +A+++ + LLE
Sbjct: 694 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN 753
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + G L +AA +GH ++ LL G
Sbjct: 754 KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHG 787
Score = 106 bits (254), Expect = 9e-23
Identities = 62/222 (27%), Positives = 104/222 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA H I L+ GA + + P +AS+ G+ D +LL++ +++
Sbjct: 698 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 757
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D N L +AA + + D+ L H A + G L++ A L +A L
Sbjct: 758 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 817
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA + + G T LH++ + L+ AD A + L AA + ++
Sbjct: 818 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 877
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+E+GA+ + G T L +AAQ+GH ++ +LLE G
Sbjct: 878 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHG 919
Score = 105 bits (253), Expect = 1e-22
Identities = 65/209 (31%), Positives = 105/209 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +AA H DI+ +L +GA V K + + L+I + + +A L++GA+V
Sbjct: 764 GRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANV 823
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A A+ LH++ Q + ++ LI ++A + A + +AL AA G++KV LL+
Sbjct: 824 EASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLI 883
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D G T L IAAQ V LLE GAD + G T + +AA+ +
Sbjct: 884 EHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQ 943
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L +YGA ++ + +P+H Q+
Sbjct: 944 IIKLLEKYGA--SSLNGCSPSPVHTMEQK 970
Score = 103 bits (248), Expect = 5e-22
Identities = 70/227 (30%), Positives = 109/227 (48%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + AA + D++ +L+ GA +E + TPL +A+R G+ + L+ GA++
Sbjct: 396 GRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANI 455
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D + L AA + +V +AL+ + TAL AA G+ + LL
Sbjct: 456 NHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLL 515
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA-----AR 534
HGA ++A G T L AA + + LL+ GA+ +G T L +A A
Sbjct: 516 QHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPAS 575
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
K + L++ GA + K G TPL +AA +GH ++ LLLEGG
Sbjct: 576 KGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGG 622
Score = 103 bits (247), Expect = 7e-22
Identities = 73/213 (34%), Positives = 104/213 (48%), Gaps = 5/213 (2%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D IR LL NGA+V +T L A+ G++D+ LL+ GAD+ A + PL +A
Sbjct: 377 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 436
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+Q + V LI A + T + G+TAL AA G+ +V + LL G D A +
Sbjct: 437 ARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSR 496
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L AA + + LL+ GA+ G T L AA E LL++GA N
Sbjct: 497 TALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNH 556
Query: 592 ESKAGFTPLHLA-----AQQGHTEMCALLLEGG 675
E G T L +A A +GH + +LL++ G
Sbjct: 557 EDVDGRTALSVAALCVPASKGHASVVSLLIDRG 589
Score = 100 bits (240), Expect = 5e-21
Identities = 62/226 (27%), Positives = 102/226 (45%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA H D++ +LL GA V+ +TPL A+ +G+ + LL GA V
Sbjct: 599 GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 658
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+I ++ L IA+ Q N +V L++ G+T LH+AA G+ + L+
Sbjct: 659 DSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALI 718
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ +G P +A+Q LLE ++ +G L +AA + +
Sbjct: 719 EQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRD 778
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
L +GA N + G L++ A + M LE G +
Sbjct: 779 IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 824
Score = 83.4 bits (197), Expect = 8e-16
Identities = 62/208 (29%), Positives = 92/208 (44%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+++++L++ GA V ++ + +T + L D LL +GA V ++ L A
Sbjct: 346 EVLQLLVKAGAHVNSE--DDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANA 403
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A + DV L+ A L G T L LAA+ G+ KV N L+ GA + ++G
Sbjct: 404 AYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGW 463
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L AA V + LL G + T L AA + LL++GA N
Sbjct: 464 TALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNK 523
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T L AA GH E+ LL+ G
Sbjct: 524 ADNEGRTALIAAAYMGHREIVEHLLDHG 551
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 130 bits (315), Expect = 4e-30
Identities = 84/228 (36%), Positives = 116/228 (50%), Gaps = 5/228 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + AA H DI+ LL++GA V E +T L A+ +G+ +I LL HGA+V
Sbjct: 306 TVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNH 365
Query: 196 ITADHYNPLHIAA-----KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D L +AA + + V + LI+ A + K G T L +AA G++ V +
Sbjct: 366 EDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVD 425
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D NG TPL AA +V TLL GA ++ G T L IA+ +
Sbjct: 426 LLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQG 485
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+E TLL+ G N AG+TPLH+AA +GH +C L+E G T
Sbjct: 486 NVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 533
Score = 118 bits (285), Expect = 2e-26
Identities = 74/219 (33%), Positives = 105/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++ LL GAAV++ E +T L IAS GNV++ LL G D
Sbjct: 441 GRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 500
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH+AA + + + ALIE A G LA++ G+ +LL
Sbjct: 501 NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILL 560
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ + DQ G +G L +AA + + L GAD +G L+I A +NQ+
Sbjct: 561 ENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLT 620
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LE GA A G T LH++ QGH EM +L+
Sbjct: 621 MAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 659
Score = 118 bits (285), Expect = 2e-26
Identities = 70/222 (31%), Positives = 117/222 (52%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P LA++ H D ++ILL N + ++ + + + L +A+ G+ DI LL HGADV
Sbjct: 540 GRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADV 599
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
AD L+I A ++ +A +E+ A + A+ +G TALH++ G++++ +L+
Sbjct: 600 NCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 659
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A+ A + A + L AA V L+E GA G T L IAA++ ++
Sbjct: 660 AYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHID 719
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LLE+GA N + G T + +AA+ GH+++ LL + G
Sbjct: 720 VVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYG 761
Score = 117 bits (282), Expect = 4e-26
Identities = 79/225 (35%), Positives = 108/225 (48%), Gaps = 5/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRL-----GNVDIAVLLLQ 174
G T + AA H +I+ LL +GA V + + +T L +A+ G+ + LL+
Sbjct: 337 GRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLID 396
Query: 175 HGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKV 354
GA+V D PL +AA + + DV L+E A + T G T L AA G+ V
Sbjct: 397 RGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASV 456
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
N LL GAA D G T L IA+ V TLL++G D G TPLH+AA
Sbjct: 457 VNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF 516
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E GA TN G P LA+Q+GH + +LLE
Sbjct: 517 EGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 561
Score = 110 bits (265), Expect = 4e-24
Identities = 73/227 (32%), Positives = 109/227 (48%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ LAAR HT ++ L+ GA + ++ T L A+ G+ ++ LL G V
Sbjct: 238 GHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKV 297
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
AD L AA + D+ L++H A + +G TAL AA G+ ++ LL
Sbjct: 298 DCADADSRTVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLL 357
Query: 370 AHGAAPDQAGKNGMTPLHIA-----AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
HGA + +G T L +A A +V + L+++GA+ K+G TPL +AA
Sbjct: 358 DHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAY 417
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ ++ LLE GA + G TPL AA GH + LL G
Sbjct: 418 EGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 464
Score = 108 bits (259), Expect = 2e-23
Identities = 67/222 (30%), Positives = 109/222 (49%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A+ + +++R LL G + TPLH+A+ G+ I L++ GA
Sbjct: 474 GRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 533
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I D P +A+++ ++D L+E+ + + G AL +AA G+ + LL
Sbjct: 534 NEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLF 593
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+HGA + +G L+I A +Q +A LE GA+ +A G T LH++ + ME
Sbjct: 594 SHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHME 653
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ Y A NA + L AA QGH ++ LL+E G
Sbjct: 654 MVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHG 695
Score = 106 bits (254), Expect = 9e-23
Identities = 63/214 (29%), Positives = 104/214 (48%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A H ++ +L+ GA V+ ++ TPL +A+ G+VD+ LLL+ GADV +
Sbjct: 383 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 442
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
PL AA + V L+ A + + +G T L +A+ GN++V LL G +
Sbjct: 443 TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 502
Query: 394 AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEY 573
G TPLH+AA + + L+E+GA + +G P +A+++ + LLE
Sbjct: 503 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN 562
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + G L +AA +GH ++ LL G
Sbjct: 563 KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHG 596
Score = 106 bits (254), Expect = 9e-23
Identities = 62/222 (27%), Positives = 104/222 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA H I L+ GA + + P +AS+ G+ D +LL++ +++
Sbjct: 507 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 566
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D N L +AA + + D+ L H A + G L++ A L +A L
Sbjct: 567 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 626
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA + + G T LH++ + L+ AD A + L AA + ++
Sbjct: 627 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 686
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+E+GA+ + G T L +AAQ+GH ++ +LLE G
Sbjct: 687 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHG 728
Score = 105 bits (253), Expect = 1e-22
Identities = 65/209 (31%), Positives = 105/209 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +AA H DI+ +L +GA V K + + L+I + + +A L++GA+V
Sbjct: 573 GRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANV 632
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A A+ LH++ Q + ++ LI ++A + A + +AL AA G++KV LL+
Sbjct: 633 EASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLI 692
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D G T L IAAQ V LLE GAD + G T + +AA+ +
Sbjct: 693 EHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQ 752
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L +YGA ++ + +P+H Q+
Sbjct: 753 IIKLLEKYGA--SSLNGCSPSPVHTMEQK 779
Score = 103 bits (246), Expect = 9e-22
Identities = 73/213 (34%), Positives = 104/213 (48%), Gaps = 5/213 (2%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D IR LL NGA+V +T L A+ G++D+ LL+ GAD+ A + PL +A
Sbjct: 186 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 245
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+Q + V LI A + T + G+TAL AA G+ +V + LL G D A +
Sbjct: 246 ARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSR 305
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L AA + + LL+ GA+ G T L AA E LL++GA N
Sbjct: 306 TVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNH 365
Query: 592 ESKAGFTPLHLA-----AQQGHTEMCALLLEGG 675
E G T L +A A +GH + +LL++ G
Sbjct: 366 EDVDGRTALSVAALCVPASKGHASVVSLLIDRG 398
Score = 102 bits (244), Expect = 2e-21
Identities = 69/227 (30%), Positives = 108/227 (47%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + AA + D++ +L+ GA +E + TPL +A+R G+ + L+ GA++
Sbjct: 205 GRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANI 264
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D + L AA + +V +AL+ + T L AA G+ + LL
Sbjct: 265 NHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIVLNLL 324
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA-----AR 534
HGA ++A G T L AA + + LL+ GA+ +G T L +A A
Sbjct: 325 QHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPAS 384
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
K + L++ GA + K G TPL +AA +GH ++ LLLEGG
Sbjct: 385 KGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGG 431
Score = 100 bits (240), Expect = 5e-21
Identities = 62/226 (27%), Positives = 102/226 (45%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA H D++ +LL GA V+ +TPL A+ +G+ + LL GA V
Sbjct: 408 GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 467
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+I ++ L IA+ Q N +V L++ G+T LH+AA G+ + L+
Sbjct: 468 DSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALI 527
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ +G P +A+Q LLE ++ +G L +AA + +
Sbjct: 528 EQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRD 587
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
L +GA N + G L++ A + M LE G +
Sbjct: 588 IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 633
Score = 83.0 bits (196), Expect = 1e-15
Identities = 62/208 (29%), Positives = 92/208 (44%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+++++L++ GA V ++ + +T + L D LL +GA V ++ L A
Sbjct: 155 EVLQLLVKAGAHVNSE--DDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANA 212
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A + DV L+ A L G T L LAA+ G+ KV N L+ GA + ++G
Sbjct: 213 AYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGW 272
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L AA V + LL G + T L AA + LL++GA N
Sbjct: 273 TALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIVLNLLQHGAEVNK 332
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T L AA GH E+ LL+ G
Sbjct: 333 ADNEGRTALIAAAYMGHREIVEHLLDHG 360
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 129 bits (312), Expect = 9e-30
Identities = 72/222 (32%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+H+A ++ +LL +V AK ++ T LH A++ G+ LLL+ A
Sbjct: 470 RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNAS 529
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + + P+H+A + ++ L+ ++ K + LH AA G+L + LL
Sbjct: 530 VNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Query: 367 LAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
G + + +G TPLH+AAQ VA L++ +D + TPLH+AA
Sbjct: 590 AKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH 649
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TA LL GA A + G+T LHLAA+ GH LL+E
Sbjct: 650 TSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVE 691
Score = 127 bits (306), Expect = 5e-29
Identities = 78/223 (34%), Positives = 114/223 (51%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLL-QHGAD 186
G TP+H+A + +I+RILLR G V + ++ PLH A+ G++ I LL Q G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PLH+AA++ ++ VA LI+ + + + T LH+AA+ G+ A LL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + +G T LH+AA+ A L+E+ AD A T LH+AA
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E L+ + + + G + LHLAAQ H + LL G
Sbjct: 717 EVVEELVSADVIDLFDEQ-GLSALHLAAQGRHAQTVETLLRHG 758
Score = 126 bits (305), Expect = 6e-29
Identities = 76/213 (35%), Positives = 111/213 (52%), Gaps = 1/213 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H AA+ R+LL A+V E +TP+H+A + G +I +LL+ G DV
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D + PLH AA Q + + L + + A T G T LHLAA+ G+ +VA +L+
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+ + TPLH+AA+ + A LL +GA +AV +G+T LH+AAR + T
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLAT 685
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
L+E A A T LHLAA GH+E+
Sbjct: 686 VKLLVEEKADVLARGPLNQTALHLAAAHGHSEV 718
Score = 120 bits (289), Expect = 5e-27
Identities = 72/227 (31%), Positives = 104/227 (45%), Gaps = 1/227 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLA A + + LL N A R TPLH+A + LLL V
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A D + LH AA+ + L+E NA + +G T +H+A ++G + +LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQM 546
G GK+ PLH AA + L ++ G A +G TPLH+AA++
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 617
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
A L++ + N S TPLH+AA+ GHT LLL G G +
Sbjct: 618 RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKE 664
Score = 108 bits (259), Expect = 2e-23
Identities = 64/194 (32%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
P+H AA H I+++L + G +V A+ + +TPLH+A++ G+ +A +L+ +DV
Sbjct: 573 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 632
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA+ + A L+ A A T G+TALHLAA+ G+L LL+
Sbjct: 633 CSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEE 692
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A G T LH+AA + V L+ + G + LH+AA+ +T
Sbjct: 693 KADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTV 751
Query: 556 ATLLEYGALTNAES 597
TLL +GA N +S
Sbjct: 752 ETLLRHGAHINLQS 765
Score = 104 bits (249), Expect = 4e-22
Identities = 64/184 (34%), Positives = 95/184 (51%), Gaps = 3/184 (1%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ G TP+HLAA+ H + RIL+ + V + QTPLH+A+ G+ A LLL G
Sbjct: 601 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 660
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A+T+D Y LH+AA+ + L+E A + A TALHLAA +G+ +V
Sbjct: 661 AGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVE 720
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAA 531
L++ D + G++ LH+AAQ TLL GA + + GH P
Sbjct: 721 ELVSADVI-DLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLL 779
Query: 532 RKNQ 543
R+++
Sbjct: 780 RRSK 783
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D A +G + LH+A + Q+ A LL A+ + G TPLH+A + LL
Sbjct: 432 DLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLL 491
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NA+ + +T LH AAQ G LLLE
Sbjct: 492 ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLE 525
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D +G + LH+A Q E A LL A N ++ G TPLH+A ++ + L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 661 LL 666
LL
Sbjct: 490 LL 491
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 129 bits (312), Expect = 9e-30
Identities = 72/222 (32%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+H+A ++ +LL +V AK ++ T LH A++ G+ LLL+ A
Sbjct: 470 RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNAS 529
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + + P+H+A + ++ L+ ++ K + LH AA G+L + LL
Sbjct: 530 VNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Query: 367 LAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
G + + +G TPLH+AAQ VA L++ +D + TPLH+AA
Sbjct: 590 AKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH 649
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TA LL GA A + G+T LHLAA+ GH LL+E
Sbjct: 650 TSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVE 691
Score = 127 bits (306), Expect = 5e-29
Identities = 78/223 (34%), Positives = 114/223 (51%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLL-QHGAD 186
G TP+H+A + +I+RILLR G V + ++ PLH A+ G++ I LL Q G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PLH+AA++ ++ VA LI+ + + + T LH+AA+ G+ A LL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + +G T LH+AA+ A L+E+ AD A T LH+AA
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E L+ + + + G + LHLAAQ H + LL G
Sbjct: 717 EVVEELVSADVIDLFDEQ-GLSALHLAAQGRHAQTVETLLRHG 758
Score = 126 bits (305), Expect = 6e-29
Identities = 76/213 (35%), Positives = 111/213 (52%), Gaps = 1/213 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H AA+ R+LL A+V E +TP+H+A + G +I +LL+ G DV
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D + PLH AA Q + + L + + A T G T LHLAA+ G+ +VA +L+
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+ + TPLH+AA+ + A LL +GA +AV +G+T LH+AAR + T
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLAT 685
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
L+E A A T LHLAA GH+E+
Sbjct: 686 VKLLVEEKADVLARGPLNQTALHLAAAHGHSEV 718
Score = 120 bits (289), Expect = 5e-27
Identities = 72/227 (31%), Positives = 104/227 (45%), Gaps = 1/227 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLA A + + LL N A R TPLH+A + LLL V
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A D + LH AA+ + L+E NA + +G T +H+A ++G + +LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQM 546
G GK+ PLH AA + L ++ G A +G TPLH+AA++
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 617
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
A L++ + N S TPLH+AA+ GHT LLL G G +
Sbjct: 618 RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKE 664
Score = 108 bits (259), Expect = 2e-23
Identities = 64/194 (32%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
P+H AA H I+++L + G +V A+ + +TPLH+A++ G+ +A +L+ +DV
Sbjct: 573 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 632
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA+ + A L+ A A T G+TALHLAA+ G+L LL+
Sbjct: 633 CSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEE 692
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A G T LH+AA + V L+ + G + LH+AA+ +T
Sbjct: 693 KADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTV 751
Query: 556 ATLLEYGALTNAES 597
TLL +GA N +S
Sbjct: 752 ETLLRHGAHINLQS 765
Score = 104 bits (249), Expect = 4e-22
Identities = 64/184 (34%), Positives = 95/184 (51%), Gaps = 3/184 (1%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ G TP+HLAA+ H + RIL+ + V + QTPLH+A+ G+ A LLL G
Sbjct: 601 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 660
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A+T+D Y LH+AA+ + L+E A + A TALHLAA +G+ +V
Sbjct: 661 AGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVE 720
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAA 531
L++ D + G++ LH+AAQ TLL GA + + GH P
Sbjct: 721 ELVSADVI-DLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLL 779
Query: 532 RKNQ 543
R+++
Sbjct: 780 RRSK 783
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D A +G + LH+A + Q+ A LL A+ + G TPLH+A + LL
Sbjct: 432 DLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLL 491
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NA+ + +T LH AAQ G LLLE
Sbjct: 492 ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLE 525
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D +G + LH+A Q E A LL A N ++ G TPLH+A ++ + L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 661 LL 666
LL
Sbjct: 490 LL 491
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 129 bits (312), Expect = 9e-30
Identities = 72/222 (32%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+H+A ++ +LL +V AK ++ T LH A++ G+ LLL+ A
Sbjct: 518 RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNAS 577
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + + P+H+A + ++ L+ ++ K + LH AA G+L + LL
Sbjct: 578 VNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 637
Query: 367 LAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
G + + +G TPLH+AAQ VA L++ +D + TPLH+AA
Sbjct: 638 AKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH 697
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TA LL GA A + G+T LHLAA+ GH LL+E
Sbjct: 698 TSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVE 739
Score = 126 bits (305), Expect = 6e-29
Identities = 78/223 (34%), Positives = 114/223 (51%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLL-QHGAD 186
G TP+H+A + +I+RILLR G V + ++ PLH A+ G++ I LL Q G
Sbjct: 585 GRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 644
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PLH+AA++ ++ VA LI+ + + + T LH+AA+ G+ A LL
Sbjct: 645 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 704
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + +G T LH+AA+ A L+E+ AD A T LH+AA
Sbjct: 705 LHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 764
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E L+ + + + G + LHLAAQ H + LL G
Sbjct: 765 EVVEELVSADVIDLFDEQ-GLSALHLAAQGRHAQTVETLLRHG 806
Score = 125 bits (302), Expect = 1e-28
Identities = 75/213 (35%), Positives = 111/213 (52%), Gaps = 1/213 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H AA+ R+LL A+V E +TP+H+A + G +I +LL+ G DV
Sbjct: 554 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 613
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D + PLH AA Q + + L + + A T G T LHLAA+ G+ +VA +L+
Sbjct: 614 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 673
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+ + TPLH+AA+ + A LL +GA +A+ +G+T LH+AAR + T
Sbjct: 674 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLAT 733
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
L+E A A T LHLAA GH+E+
Sbjct: 734 VKLLVEEKADVLARGPLNQTALHLAAAHGHSEV 766
Score = 120 bits (289), Expect = 5e-27
Identities = 72/227 (31%), Positives = 104/227 (45%), Gaps = 1/227 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLA A + + LL N A R TPLH+A + LLL V
Sbjct: 486 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A D + LH AA+ + L+E NA + +G T +H+A ++G + +LL
Sbjct: 546 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 605
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQM 546
G GK+ PLH AA + L ++ G A +G TPLH+AA++
Sbjct: 606 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 665
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
A L++ + N S TPLH+AA+ GHT LLL G G +
Sbjct: 666 RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKE 712
Score = 107 bits (258), Expect = 3e-23
Identities = 64/194 (32%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
P+H AA H I+++L + G +V A+ + +TPLH+A++ G+ +A +L+ +DV
Sbjct: 621 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 680
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA+ + A L+ A A T G+TALHLAA+ G+L LL+
Sbjct: 681 CSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEE 740
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A G T LH+AA + V L+ + G + LH+AA+ +T
Sbjct: 741 KADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTV 799
Query: 556 ATLLEYGALTNAES 597
TLL +GA N +S
Sbjct: 800 ETLLRHGAHINLQS 813
Score = 103 bits (247), Expect = 7e-22
Identities = 64/184 (34%), Positives = 95/184 (51%), Gaps = 3/184 (1%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ G TP+HLAA+ H + RIL+ + V + QTPLH+A+ G+ A LLL G
Sbjct: 649 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 708
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A+T+D Y LH+AA+ + L+E A + A TALHLAA +G+ +V
Sbjct: 709 AGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVE 768
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAA 531
L++ D + G++ LH+AAQ TLL GA + + GH P
Sbjct: 769 ELVSADVI-DLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLL 827
Query: 532 RKNQ 543
R+++
Sbjct: 828 RRSK 831
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D A +G + LH+A + Q+ A LL A+ + G TPLH+A + LL
Sbjct: 480 DLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLL 539
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NA+ + +T LH AAQ G LLLE
Sbjct: 540 ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLE 573
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D +G + LH+A Q E A LL A N ++ G TPLH+A ++ + L
Sbjct: 478 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 537
Query: 661 LL 666
LL
Sbjct: 538 LL 539
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 129 bits (312), Expect = 9e-30
Identities = 72/222 (32%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+H+A ++ +LL +V AK ++ T LH A++ G+ LLL+ A
Sbjct: 470 RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNAS 529
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + + P+H+A + ++ L+ ++ K + LH AA G+L + LL
Sbjct: 530 VNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Query: 367 LAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
G + + +G TPLH+AAQ VA L++ +D + TPLH+AA
Sbjct: 590 AKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH 649
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TA LL GA A + G+T LHLAA+ GH LL+E
Sbjct: 650 TSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVE 691
Score = 128 bits (309), Expect = 2e-29
Identities = 77/213 (36%), Positives = 111/213 (52%), Gaps = 1/213 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H AA+ R+LL A+V E +TP+H+A + G +I +LL+ G DV
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D + PLH AA Q + + L + + A T G T LHLAA+ G+ +VA +L+
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+ + TPLH+AA+ + A LL +GA KAV +G+T LH+AAR + T
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLAT 685
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
L+E A A T LHLAA GH+E+
Sbjct: 686 VKLLVEEKADVLARGPLNQTALHLAAAHGHSEV 718
Score = 126 bits (303), Expect = 1e-28
Identities = 78/223 (34%), Positives = 113/223 (50%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLL-QHGAD 186
G TP+H+A + +I+RILLR G V + ++ PLH A+ G++ I LL Q G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PLH+AA++ ++ VA LI+ + + + T LH+AA+ G+ A LL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA +G T LH+AA+ A L+E+ AD A T LH+AA
Sbjct: 657 LHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E L+ + + + G + LHLAAQ H + LL G
Sbjct: 717 EVVEELVSADVIDLFDEQ-GLSALHLAAQGRHAQTVETLLRHG 758
Score = 120 bits (288), Expect = 7e-27
Identities = 72/225 (32%), Positives = 103/225 (45%), Gaps = 1/225 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLA A + + LL N A R TPLH+A + LLL V
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A D + LH AA+ + L+E NA + +G T +H+A ++G + +LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQM 546
G GK+ PLH AA + L ++ G A +G TPLH+AA++
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 617
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
A L++ + N S TPLH+AA+ GHT LLL G G
Sbjct: 618 RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 662
Score = 108 bits (259), Expect = 2e-23
Identities = 64/194 (32%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
P+H AA H I+++L + G +V A+ + +TPLH+A++ G+ +A +L+ +DV
Sbjct: 573 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 632
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA+ + A L+ A A T G+TALHLAA+ G+L LL+
Sbjct: 633 CSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEE 692
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A G T LH+AA + V L+ + G + LH+AA+ +T
Sbjct: 693 KADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTV 751
Query: 556 ATLLEYGALTNAES 597
TLL +GA N +S
Sbjct: 752 ETLLRHGAHINLQS 765
Score = 105 bits (251), Expect = 2e-22
Identities = 64/184 (34%), Positives = 96/184 (52%), Gaps = 3/184 (1%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ G TP+HLAA+ H + RIL+ + V + QTPLH+A+ G+ A LLL G
Sbjct: 601 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 660
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A +A+T+D Y LH+AA+ + L+E A + A TALHLAA +G+ +V
Sbjct: 661 AGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVE 720
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAA 531
L++ D + G++ LH+AAQ TLL GA + + GH P
Sbjct: 721 ELVSADVI-DLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLL 779
Query: 532 RKNQ 543
R+++
Sbjct: 780 RRSK 783
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D A +G + LH+A + Q+ A LL A+ + G TPLH+A + LL
Sbjct: 432 DLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLL 491
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NA+ + +T LH AAQ G LLLE
Sbjct: 492 ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLE 525
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D +G + LH+A Q E A LL A N ++ G TPLH+A ++ + L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 661 LL 666
LL
Sbjct: 490 LL 491
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 129 bits (312), Expect = 9e-30
Identities = 72/222 (32%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+H+A ++ +LL +V AK ++ T LH A++ G+ LLL+ A
Sbjct: 470 RGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNAS 529
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + + P+H+A + ++ L+ ++ K + LH AA G+L + LL
Sbjct: 530 VNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Query: 367 LAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
G + + +G TPLH+AAQ VA L++ +D + TPLH+AA
Sbjct: 590 AKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH 649
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TA LL GA A + G+T LHLAA+ GH LL+E
Sbjct: 650 TSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVE 691
Score = 127 bits (306), Expect = 5e-29
Identities = 78/223 (34%), Positives = 114/223 (51%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLL-QHGAD 186
G TP+H+A + +I+RILLR G V + ++ PLH A+ G++ I LL Q G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PLH+AA++ ++ VA LI+ + + + T LH+AA+ G+ A LL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + +G T LH+AA+ A L+E+ AD A T LH+AA
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E L+ + + + G + LHLAAQ H + LL G
Sbjct: 717 EVVEELVSADVIDLFDEQ-GLSALHLAAQGRHAQTVETLLRHG 758
Score = 126 bits (305), Expect = 6e-29
Identities = 76/213 (35%), Positives = 111/213 (52%), Gaps = 1/213 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H AA+ R+LL A+V E +TP+H+A + G +I +LL+ G DV
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D + PLH AA Q + + L + + A T G T LHLAA+ G+ +VA +L+
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+ + TPLH+AA+ + A LL +GA +AV +G+T LH+AAR + T
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLAT 685
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
L+E A A T LHLAA GH+E+
Sbjct: 686 VKLLVEEKADVLARGPLNQTALHLAAAHGHSEV 718
Score = 120 bits (289), Expect = 5e-27
Identities = 72/227 (31%), Positives = 104/227 (45%), Gaps = 1/227 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLA A + + LL N A R TPLH+A + LLL V
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A D + LH AA+ + L+E NA + +G T +H+A ++G + +LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQM 546
G GK+ PLH AA + L ++ G A +G TPLH+AA++
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 617
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
A L++ + N S TPLH+AA+ GHT LLL G G +
Sbjct: 618 RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKE 664
Score = 108 bits (259), Expect = 2e-23
Identities = 64/194 (32%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
P+H AA H I+++L + G +V A+ + +TPLH+A++ G+ +A +L+ +DV
Sbjct: 573 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 632
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA+ + A L+ A A T G+TALHLAA+ G+L LL+
Sbjct: 633 CSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEE 692
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A G T LH+AA + V L+ + G + LH+AA+ +T
Sbjct: 693 KADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTV 751
Query: 556 ATLLEYGALTNAES 597
TLL +GA N +S
Sbjct: 752 ETLLRHGAHINLQS 765
Score = 104 bits (249), Expect = 4e-22
Identities = 64/184 (34%), Positives = 95/184 (51%), Gaps = 3/184 (1%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ G TP+HLAA+ H + RIL+ + V + QTPLH+A+ G+ A LLL G
Sbjct: 601 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 660
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A+T+D Y LH+AA+ + L+E A + A TALHLAA +G+ +V
Sbjct: 661 AGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVE 720
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAA 531
L++ D + G++ LH+AAQ TLL GA + + GH P
Sbjct: 721 ELVSADVI-DLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLL 779
Query: 532 RKNQ 543
R+++
Sbjct: 780 RRSK 783
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D A +G + LH+A + Q+ A LL A+ + G TPLH+A + LL
Sbjct: 432 DLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLL 491
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NA+ + +T LH AAQ G LLLE
Sbjct: 492 ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLE 525
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCAL 660
D +G + LH+A Q E A LL A N ++ G TPLH+A ++ + L
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 661 LL 666
LL
Sbjct: 490 LL 491
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens cDNA
FLJ45589 fis, clone BRTHA3014547, weakly similar to
Ankyrin 1. ).
Length = 1375
Score = 128 bits (308), Expect = 3e-29
Identities = 83/228 (36%), Positives = 115/228 (50%), Gaps = 5/228 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + AA DI+ LL++GA V E +T L A+ +G+ +I LL HGA+V
Sbjct: 592 TALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNH 651
Query: 196 ITADHYNPLHIAA-----KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D L +AA + + V + LI+ A + K G T L +AA G++ V +
Sbjct: 652 EDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVD 711
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL GA D NG TPL AA +V TLL GA ++ G T L IA+ +
Sbjct: 712 LLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQG 771
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+E TLL+ G N AG+TPLH+AA +GH +C L+E G T
Sbjct: 772 NVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 819
Score = 118 bits (285), Expect = 2e-26
Identities = 74/219 (33%), Positives = 105/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++ LL GAAV++ E +T L IAS GNV++ LL G D
Sbjct: 727 GRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 786
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH+AA + + + ALIE A G LA++ G+ +LL
Sbjct: 787 NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILL 846
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ + DQ G +G L +AA + + L GAD +G L+I A +NQ+
Sbjct: 847 ENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLT 906
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LE GA A G T LH++ QGH EM +L+
Sbjct: 907 MAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 945
Score = 118 bits (285), Expect = 2e-26
Identities = 70/222 (31%), Positives = 117/222 (52%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P LA++ H D ++ILL N + ++ + + + L +A+ G+ DI LL HGADV
Sbjct: 826 GRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADV 885
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
AD L+I A ++ +A +E+ A + A+ +G TALH++ G++++ +L+
Sbjct: 886 NCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 945
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A+ A + A + L AA V L+E GA G T L IAA++ ++
Sbjct: 946 AYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHID 1005
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LLE+GA N + G T + +AA+ GH+++ LL + G
Sbjct: 1006 VVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYG 1047
Score = 117 bits (282), Expect = 4e-26
Identities = 79/225 (35%), Positives = 108/225 (48%), Gaps = 5/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRL-----GNVDIAVLLLQ 174
G T + AA H +I+ LL +GA V + + +T L +A+ G+ + LL+
Sbjct: 623 GRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLID 682
Query: 175 HGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKV 354
GA+V D PL +AA + + DV L+E A + T G T L AA G+ V
Sbjct: 683 RGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASV 742
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
N LL GAA D G T L IA+ V TLL++G D G TPLH+AA
Sbjct: 743 VNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF 802
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E GA TN G P LA+Q+GH + +LLE
Sbjct: 803 EGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 847
Score = 108 bits (259), Expect = 2e-23
Identities = 67/222 (30%), Positives = 109/222 (49%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A+ + +++R LL G + TPLH+A+ G+ I L++ GA
Sbjct: 760 GRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 819
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I D P +A+++ ++D L+E+ + + G AL +AA G+ + LL
Sbjct: 820 NEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLF 879
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+HGA + +G L+I A +Q +A LE GA+ +A G T LH++ + ME
Sbjct: 880 SHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHME 939
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ Y A NA + L AA QGH ++ LL+E G
Sbjct: 940 MVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHG 981
Score = 106 bits (254), Expect = 9e-23
Identities = 63/214 (29%), Positives = 104/214 (48%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A H ++ +L+ GA V+ ++ TPL +A+ G+VD+ LLL+ GADV +
Sbjct: 669 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 728
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
PL AA + V L+ A + + +G T L +A+ GN++V LL G +
Sbjct: 729 TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 788
Query: 394 AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEY 573
G TPLH+AA + + L+E+GA + +G P +A+++ + LLE
Sbjct: 789 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN 848
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + G L +AA +GH ++ LL G
Sbjct: 849 KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHG 882
Score = 106 bits (254), Expect = 9e-23
Identities = 62/222 (27%), Positives = 104/222 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA H I L+ GA + + P +AS+ G+ D +LL++ +++
Sbjct: 793 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 852
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D N L +AA + + D+ L H A + G L++ A L +A L
Sbjct: 853 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 912
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA + + G T LH++ + L+ AD A + L AA + ++
Sbjct: 913 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 972
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+E+GA+ + G T L +AAQ+GH ++ +LLE G
Sbjct: 973 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHG 1014
Score = 105 bits (253), Expect = 1e-22
Identities = 65/209 (31%), Positives = 105/209 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +AA H DI+ +L +GA V K + + L+I + + +A L++GA+V
Sbjct: 859 GRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANV 918
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A A+ LH++ Q + ++ LI ++A + A + +AL AA G++KV LL+
Sbjct: 919 EASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLI 978
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D G T L IAAQ V LLE GAD + G T + +AA+ +
Sbjct: 979 EHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQ 1038
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L +YGA ++ + +P+H Q+
Sbjct: 1039 IIKLLEKYGA--SSLNGCSPSPVHTMEQK 1065
Score = 103 bits (248), Expect = 5e-22
Identities = 73/213 (34%), Positives = 105/213 (49%), Gaps = 5/213 (2%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D IR LL NGA+V +T L A+ G++D+ LL+ GAD+ A + PL +A
Sbjct: 472 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 531
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+Q + V LI A + T + G+TAL AA G+ +V + LL G D A +
Sbjct: 532 ARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSR 591
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L AA ++ + LL+ GA+ G T L AA E LL++GA N
Sbjct: 592 TALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNH 651
Query: 592 ESKAGFTPLHLA-----AQQGHTEMCALLLEGG 675
E G T L +A A +GH + +LL++ G
Sbjct: 652 EDVDGRTALSVAALCVPASKGHASVVSLLIDRG 684
Score = 103 bits (247), Expect = 7e-22
Identities = 70/227 (30%), Positives = 108/227 (47%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + AA + D++ +L+ GA +E + TPL +A+R G+ + L+ GA++
Sbjct: 491 GRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANI 550
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D + L AA + +V +AL+ + TAL AA G + LL
Sbjct: 551 NHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGREDIVLNLL 610
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA-----AR 534
HGA ++A G T L AA + + LL+ GA+ +G T L +A A
Sbjct: 611 QHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPAS 670
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
K + L++ GA + K G TPL +AA +GH ++ LLLEGG
Sbjct: 671 KGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGG 717
Score = 100 bits (240), Expect = 5e-21
Identities = 62/226 (27%), Positives = 102/226 (45%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA H D++ +LL GA V+ +TPL A+ +G+ + LL GA V
Sbjct: 694 GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 753
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+I ++ L IA+ Q N +V L++ G+T LH+AA G+ + L+
Sbjct: 754 DSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALI 813
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ +G P +A+Q LLE ++ +G L +AA + +
Sbjct: 814 EQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRD 873
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
L +GA N + G L++ A + M LE G +
Sbjct: 874 IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 919
Score = 83.8 bits (198), Expect = 6e-16
Identities = 62/208 (29%), Positives = 93/208 (44%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+++++L++ GA V ++ + +T + L D LL +GA V ++ L A
Sbjct: 441 EVLQLLVKAGAHVNSE--DDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANA 498
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A + DV L+ A L G T L LAA+ G+ KV N L+ GA + ++G
Sbjct: 499 AYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGW 558
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L AA V + LL G + T L AA + + LL++GA N
Sbjct: 559 TALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGREDIVLNLLQHGAEVNK 618
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T L AA GH E+ LL+ G
Sbjct: 619 ADNEGRTALIAAAYMGHREIVEHLLDHG 646
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens cDNA
FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 128 bits (308), Expect = 3e-29
Identities = 72/222 (32%), Positives = 109/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+H+A ++ LL +V AK ++ T LH A++ G+ LLL+ A
Sbjct: 470 RGSTPLHMAVERRVRGVVERLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNAS 529
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + + P+H+A + ++ L+ ++ K + LH AA G+L + LL
Sbjct: 530 VNEVDFEGLTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Query: 367 LAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
G + + +G TPLH+AAQ VA L++ +D + TPLH+AA
Sbjct: 590 AKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGH 649
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TA LL GA A + G+T LHLAA+ GH LL+E
Sbjct: 650 TSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVE 691
Score = 126 bits (303), Expect = 1e-28
Identities = 78/223 (34%), Positives = 114/223 (51%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLL-QHGAD 186
G TP+H+A + +I+RILLR G V + ++ PLH A+ G++ I LL Q G
Sbjct: 537 GLTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PLH+AA++ ++ VA LI+ + + + T LH+AA+ G+ A LL
Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLL 656
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + +G T LH+AA+ A L+E+ AD A T LH+AA
Sbjct: 657 LHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHS 716
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E L+ + + + G + LHLAAQ H + LL G
Sbjct: 717 EVVEELVSADVIDLFDEQ-GLSALHLAAQGRHAQTVETLLRHG 758
Score = 125 bits (302), Expect = 1e-28
Identities = 76/213 (35%), Positives = 110/213 (51%), Gaps = 1/213 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H AA+ R+LL A+V E TP+H+A + G +I +LL+ G DV
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D + PLH AA Q + + L + + A T G T LHLAA+ G+ +VA +L+
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+ + TPLH+AA+ + A LL +GA +AV +G+T LH+AAR + T
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLAT 685
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
L+E A A T LHLAA GH+E+
Sbjct: 686 VKLLVEEKADVLARGPLNQTALHLAAAHGHSEV 718
Score = 119 bits (286), Expect = 1e-26
Identities = 71/227 (31%), Positives = 103/227 (45%), Gaps = 1/227 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLA A + + LL N A R TPLH+A + LL V
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKISV 497
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A D + LH AA+ + L+E NA + +G T +H+A ++G + +LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILL 557
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQM 546
G GK+ PLH AA + L ++ G A +G TPLH+AA++
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 617
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
A L++ + N S TPLH+AA+ GHT LLL G G +
Sbjct: 618 RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKE 664
Score = 108 bits (259), Expect = 2e-23
Identities = 64/194 (32%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
P+H AA H I+++L + G +V A+ + +TPLH+A++ G+ +A +L+ +DV
Sbjct: 573 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 632
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ PLH+AA+ + A L+ A A T G+TALHLAA+ G+L LL+
Sbjct: 633 CSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEE 692
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A G T LH+AA + V L+ + G + LH+AA+ +T
Sbjct: 693 KADVLARGPLNQTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTV 751
Query: 556 ATLLEYGALTNAES 597
TLL +GA N +S
Sbjct: 752 ETLLRHGAHINLQS 765
Score = 104 bits (249), Expect = 4e-22
Identities = 64/184 (34%), Positives = 95/184 (51%), Gaps = 3/184 (1%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ G TP+HLAA+ H + RIL+ + V + QTPLH+A+ G+ A LLL G
Sbjct: 601 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 660
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A A+T+D Y LH+AA+ + L+E A + A TALHLAA +G+ +V
Sbjct: 661 AGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVE 720
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAA 531
L++ D + G++ LH+AAQ TLL GA + + GH P
Sbjct: 721 ELVSADVI-DLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLL 779
Query: 532 RKNQ 543
R+++
Sbjct: 780 RRSK 783
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D A +G + LH+A + Q+ A LL A+ + G TPLH+A + LL
Sbjct: 432 DLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLL 491
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NA+ + +T LH AAQ G LLLE
Sbjct: 492 ARKISVNAKDEDQWTALHFAAQNGDESSTRLLLE 525
Score = 35.1 bits (77), Expect = 0.27
Identities = 18/52 (34%), Positives = 26/52 (50%)
Frame = +1
Query: 481 DAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
D +G + LH+A Q E A LL A N ++ G TPLH+A ++
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER 481
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 125 bits (302), Expect = 1e-28
Identities = 71/218 (32%), Positives = 104/218 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GE +H+AAR H D+ ++L G+ + +E +TPLH A+ G +A L + G +V
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ G D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILD 624
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 625 VVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 662
Score = 122 bits (293), Expect = 2e-27
Identities = 69/210 (32%), Positives = 101/210 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G V+ AAR H D ++ L N ++ K + + LH+A+R G+ D+A LL G++
Sbjct: 412 GSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNP 471
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH AA + VA AL E + ++G T L A+ G + L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + K+G LH+A + Q V TLL +G ++G+TPLH+A + M
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQG 639
L E + +K G TPLHLAA G
Sbjct: 592 IVVALCEANCNLDISNKYGRTPLHLAANNG 621
Score = 111 bits (267), Expect = 3e-24
Identities = 66/220 (30%), Positives = 106/220 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + DVA L + K+ T LH AA +G VA L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QME
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME 558
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TLL G + + + G TPLH+A + G+ + L E
Sbjct: 559 VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Score = 109 bits (263), Expect = 8e-24
Identities = 66/186 (35%), Positives = 94/186 (50%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 382 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 441
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
K G ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G
Sbjct: 442 DKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAG 501
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
+ + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 502 CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 561
Query: 658 LLLEGG 675
LL G
Sbjct: 562 TLLSQG 567
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/133 (30%), Positives = 59/133 (44%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L E K+G LH+AAR + A L +G+ N + K TPLH AA
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH 488
Query: 637 GHTEMCALLLEGG 675
G+ + L E G
Sbjct: 489 GYYSVAKALCEAG 501
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 125 bits (302), Expect = 1e-28
Identities = 71/218 (32%), Positives = 104/218 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GE +H+AAR H D+ ++L G+ + +E +TPLH A+ G +A L + G +V
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ G D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILD 624
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 625 VVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 662
Score = 122 bits (293), Expect = 2e-27
Identities = 69/210 (32%), Positives = 101/210 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G V+ AAR H D ++ L N ++ K + + LH+A+R G+ D+A LL G++
Sbjct: 412 GSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNP 471
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH AA + VA AL E + ++G T L A+ G + L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + K+G LH+A + Q V TLL +G ++G+TPLH+A + M
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQG 639
L E + +K G TPLHLAA G
Sbjct: 592 IVVALCEANCNLDISNKYGRTPLHLAANNG 621
Score = 111 bits (267), Expect = 3e-24
Identities = 66/220 (30%), Positives = 106/220 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + DVA L + K+ T LH AA +G VA L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QME
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME 558
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TLL G + + + G TPLH+A + G+ + L E
Sbjct: 559 VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Score = 109 bits (263), Expect = 8e-24
Identities = 66/186 (35%), Positives = 94/186 (50%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 382 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 441
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
K G ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G
Sbjct: 442 DKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAG 501
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
+ + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 502 CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 561
Query: 658 LLLEGG 675
LL G
Sbjct: 562 TLLSQG 567
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/133 (30%), Positives = 59/133 (44%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L E K+G LH+AAR + A L +G+ N + K TPLH AA
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH 488
Query: 637 GHTEMCALLLEGG 675
G+ + L E G
Sbjct: 489 GYYSVAKALCEAG 501
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 125 bits (302), Expect = 1e-28
Identities = 71/218 (32%), Positives = 104/218 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GE +H+AAR H D+ ++L G+ + +E +TPLH A+ G +A L + G +V
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ G D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILD 624
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 625 VVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 662
Score = 122 bits (293), Expect = 2e-27
Identities = 69/210 (32%), Positives = 101/210 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G V+ AAR H D ++ L N ++ K + + LH+A+R G+ D+A LL G++
Sbjct: 412 GSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNP 471
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH AA + VA AL E + ++G T L A+ G + L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + K+G LH+A + Q V TLL +G ++G+TPLH+A + M
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQG 639
L E + +K G TPLHLAA G
Sbjct: 592 IVVALCEANCNLDISNKYGRTPLHLAANNG 621
Score = 111 bits (267), Expect = 3e-24
Identities = 66/220 (30%), Positives = 106/220 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + DVA L + K+ T LH AA +G VA L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QME
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME 558
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TLL G + + + G TPLH+A + G+ + L E
Sbjct: 559 VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Score = 109 bits (263), Expect = 8e-24
Identities = 66/186 (35%), Positives = 94/186 (50%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 382 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 441
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
K G ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G
Sbjct: 442 DKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAG 501
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
+ + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 502 CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 561
Query: 658 LLLEGG 675
LL G
Sbjct: 562 TLLSQG 567
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/133 (30%), Positives = 59/133 (44%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L E K+G LH+AAR + A L +G+ N + K TPLH AA
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH 488
Query: 637 GHTEMCALLLEGG 675
G+ + L E G
Sbjct: 489 GYYSVAKALCEAG 501
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 125 bits (302), Expect = 1e-28
Identities = 71/218 (32%), Positives = 104/218 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GE +H+AAR H D+ ++L G+ + +E +TPLH A+ G +A L + G +V
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ G D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILD 624
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 625 VVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 662
Score = 122 bits (293), Expect = 2e-27
Identities = 69/210 (32%), Positives = 101/210 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G V+ AAR H D ++ L N ++ K + + LH+A+R G+ D+A LL G++
Sbjct: 412 GSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNP 471
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH AA + VA AL E + ++G T L A+ G + L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + K+G LH+A + Q V TLL +G ++G+TPLH+A + M
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQG 639
L E + +K G TPLHLAA G
Sbjct: 592 IVVALCEANCNLDISNKYGRTPLHLAANNG 621
Score = 111 bits (267), Expect = 3e-24
Identities = 66/220 (30%), Positives = 106/220 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + DVA L + K+ T LH AA +G VA L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QME
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME 558
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TLL G + + + G TPLH+A + G+ + L E
Sbjct: 559 VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Score = 109 bits (263), Expect = 8e-24
Identities = 66/186 (35%), Positives = 94/186 (50%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 382 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 441
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
K G ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G
Sbjct: 442 DKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAG 501
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
+ + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 502 CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 561
Query: 658 LLLEGG 675
LL G
Sbjct: 562 TLLSQG 567
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/133 (30%), Positives = 59/133 (44%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L E K+G LH+AAR + A L +G+ N + K TPLH AA
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH 488
Query: 637 GHTEMCALLLEGG 675
G+ + L E G
Sbjct: 489 GYYSVAKALCEAG 501
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 125 bits (302), Expect = 1e-28
Identities = 71/218 (32%), Positives = 104/218 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GE +H+AAR H D+ ++L G+ + +E +TPLH A+ G +A L + G +V
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ G D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILD 624
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 625 VVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 662
Score = 122 bits (293), Expect = 2e-27
Identities = 69/210 (32%), Positives = 101/210 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G V+ AAR H D ++ L N ++ K + + LH+A+R G+ D+A LL G++
Sbjct: 412 GSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNP 471
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH AA + VA AL E + ++G T L A+ G + L
Sbjct: 472 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + K+G LH+A + Q V TLL +G ++G+TPLH+A + M
Sbjct: 532 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 591
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQG 639
L E + +K G TPLHLAA G
Sbjct: 592 IVVALCEANCNLDISNKYGRTPLHLAANNG 621
Score = 111 bits (267), Expect = 3e-24
Identities = 66/220 (30%), Positives = 106/220 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + DVA L + K+ T LH AA +G VA L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QME
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME 558
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TLL G + + + G TPLH+A + G+ + L E
Sbjct: 559 VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Score = 109 bits (263), Expect = 8e-24
Identities = 66/186 (35%), Positives = 94/186 (50%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 382 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 441
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
K G ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G
Sbjct: 442 DKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAG 501
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
+ + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 502 CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 561
Query: 658 LLLEGG 675
LL G
Sbjct: 562 TLLSQG 567
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/133 (30%), Positives = 59/133 (44%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L E K+G LH+AAR + A L +G+ N + K TPLH AA
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH 488
Query: 637 GHTEMCALLLEGG 675
G+ + L E G
Sbjct: 489 GYYSVAKALCEAG 501
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 125 bits (302), Expect = 1e-28
Identities = 71/218 (32%), Positives = 104/218 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GE +H+AAR H D+ ++L G+ + +E +TPLH A+ G +A L + G +V
Sbjct: 448 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 507
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL
Sbjct: 508 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 567
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ G D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 568 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILD 627
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 628 VVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 665
Score = 122 bits (293), Expect = 2e-27
Identities = 69/210 (32%), Positives = 101/210 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G V+ AAR H D ++ L N ++ K + + LH+A+R G+ D+A LL G++
Sbjct: 415 GSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNP 474
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH AA + VA AL E + ++G T L A+ G + L
Sbjct: 475 NIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLA 534
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + K+G LH+A + Q V TLL +G ++G+TPLH+A + M
Sbjct: 535 EHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMP 594
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQG 639
L E + +K G TPLHLAA G
Sbjct: 595 IVVALCEANCNLDISNKYGRTPLHLAANNG 624
Score = 111 bits (267), Expect = 3e-24
Identities = 66/220 (30%), Positives = 106/220 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 382 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 441
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + DVA L + K+ T LH AA +G VA L
Sbjct: 442 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 501
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QME
Sbjct: 502 EAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME 561
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
TLL G + + + G TPLH+A + G+ + L E
Sbjct: 562 VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 601
Score = 109 bits (263), Expect = 8e-24
Identities = 66/186 (35%), Positives = 94/186 (50%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 385 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 444
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
K G ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G
Sbjct: 445 DKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAG 504
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
+ + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 505 CNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 564
Query: 658 LLLEGG 675
LL G
Sbjct: 565 TLLSQG 570
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/133 (30%), Positives = 59/133 (44%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 372 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 431
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L E K+G LH+AAR + A L +G+ N + K TPLH AA
Sbjct: 432 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH 491
Query: 637 GHTEMCALLLEGG 675
G+ + L E G
Sbjct: 492 GYYSVAKALCEAG 504
>AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 124 bits (299), Expect = 3e-28
Identities = 77/228 (33%), Positives = 111/228 (48%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HLAA H +++ILL+ G ++ + QT LH A+ +GN +I L+ G
Sbjct: 39 TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEG 98
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ D LH A+ A LI+ A + A K G TALHLA + + +
Sbjct: 99 CALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTR 158
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL G+ D G T LH+AA+Y+ ++ LL + G T LH+AA N
Sbjct: 159 VLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALN 218
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ A LLE GA T + AG TPL A + E+ LL + G+
Sbjct: 219 HKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGS 266
Score = 112 bits (269), Expect = 1e-24
Identities = 74/219 (33%), Positives = 106/219 (48%)
Frame = +1
Query: 28 LAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
+AA T+ + L+ GA V A + +TPLH+A+ G++ + +LL+ G D+
Sbjct: 16 VAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDG 74
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
LH A N ++ AALI L K G TALH A+ +G + A LL+ GA
Sbjct: 75 DQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANV 134
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
K G T LH+A Q LL G+ A G T LH+AAR N + LL
Sbjct: 135 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLL 194
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ +++AG T LH+AA H ++ +LLE G T
Sbjct: 195 TAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 233
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/86 (37%), Positives = 43/86 (50%)
Frame = +1
Query: 418 LHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAES 597
L +AA Q L+ KGA AV K+G TPLH+AA K + LL+ G + +
Sbjct: 14 LLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQD 72
Query: 598 KAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A G+TE+ A L+ G
Sbjct: 73 DGDQTALHRATVVGNTEIIAALIHEG 98
>AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 124 bits (299), Expect = 3e-28
Identities = 77/228 (33%), Positives = 111/228 (48%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HLAA H +++ILL+ G ++ + QT LH A+ +GN +I L+ G
Sbjct: 39 TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEG 98
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ D LH A+ A LI+ A + A K G TALHLA + + +
Sbjct: 99 CALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTR 158
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL G+ D G T LH+AA+Y+ ++ LL + G T LH+AA N
Sbjct: 159 VLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALN 218
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ A LLE GA T + AG TPL A + E+ LL + G+
Sbjct: 219 HKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGS 266
Score = 112 bits (269), Expect = 1e-24
Identities = 74/219 (33%), Positives = 106/219 (48%)
Frame = +1
Query: 28 LAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
+AA T+ + L+ GA V A + +TPLH+A+ G++ + +LL+ G D+
Sbjct: 16 VAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDG 74
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
LH A N ++ AALI L K G TALH A+ +G + A LL+ GA
Sbjct: 75 DQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANV 134
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
K G T LH+A Q LL G+ A G T LH+AAR N + LL
Sbjct: 135 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLL 194
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ +++AG T LH+AA H ++ +LLE G T
Sbjct: 195 TAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 233
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/86 (37%), Positives = 43/86 (50%)
Frame = +1
Query: 418 LHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAES 597
L +AA Q L+ KGA AV K+G TPLH+AA K + LL+ G + +
Sbjct: 14 LLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQD 72
Query: 598 KAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A G+TE+ A L+ G
Sbjct: 73 DGDQTALHRATVVGNTEIIAALIHEG 98
>AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein.
Length = 693
Score = 124 bits (298), Expect = 4e-28
Identities = 76/228 (33%), Positives = 111/228 (48%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HLAA H +++ILL+ G ++ + QT LH A+ +GN +I L+ G
Sbjct: 40 TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEG 99
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ D LH A+ A L++ A + A K G TALHLA + + +
Sbjct: 100 CALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTR 159
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL G+ D G T LH+AA+Y+ ++ LL + G T LH+AA N
Sbjct: 160 VLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALN 219
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ A LLE GA T + AG TPL A + E+ LL + G+
Sbjct: 220 HKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGS 267
Score = 111 bits (268), Expect = 2e-24
Identities = 74/219 (33%), Positives = 106/219 (48%)
Frame = +1
Query: 28 LAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
+AA T+ + L+ GA V A + +TPLH+A+ G++ + +LL+ G D+
Sbjct: 17 VAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDG 75
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
LH A N ++ AALI L K G TALH A+ +G + A LL+ GA
Sbjct: 76 DQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANV 135
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
K G T LH+A Q LL G+ A G T LH+AAR N + LL
Sbjct: 136 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLL 195
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ +++AG T LH+AA H ++ +LLE G T
Sbjct: 196 TAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 234
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/86 (37%), Positives = 43/86 (50%)
Frame = +1
Query: 418 LHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAES 597
L +AA Q L+ KGA AV K+G TPLH+AA K + LL+ G + +
Sbjct: 15 LLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQD 73
Query: 598 KAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A G+TE+ A L+ G
Sbjct: 74 DGDQTALHRATVVGNTEIIAALIHEG 99
>BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6
protein.
Length = 722
Score = 123 bits (296), Expect = 8e-28
Identities = 78/226 (34%), Positives = 111/226 (49%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+HLAA H +++ILL+ G ++ + QT LH A+ +GN +I L+ G
Sbjct: 39 TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEG 98
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ D LH A+ A L++ A + A K G TALHLA + + +
Sbjct: 99 CALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTR 158
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
+LL G+ D G T LH+AA+Y+ ++ LL + G T LH+AA N
Sbjct: 159 VLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALN 218
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
+ A LLE GA T + AG TPL A + E+ ALLL P
Sbjct: 219 HKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEV-ALLLTKAP 263
Score = 111 bits (268), Expect = 2e-24
Identities = 74/219 (33%), Positives = 106/219 (48%)
Frame = +1
Query: 28 LAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
+AA T+ + L+ GA V A + +TPLH+A+ G++ + +LL+ G D+
Sbjct: 16 VAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDG 74
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
LH A N ++ AALI L K G TALH A+ +G + A LL+ GA
Sbjct: 75 DQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANV 134
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
K G T LH+A Q LL G+ A G T LH+AAR N + LL
Sbjct: 135 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLL 194
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
+ +++AG T LH+AA H ++ +LLE G T
Sbjct: 195 TAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADT 233
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/86 (37%), Positives = 43/86 (50%)
Frame = +1
Query: 418 LHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAES 597
L +AA Q L+ KGA AV K+G TPLH+AA K + LL+ G + +
Sbjct: 14 LLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQD 72
Query: 598 KAGFTPLHLAAQQGHTEMCALLLEGG 675
T LH A G+TE+ A L+ G
Sbjct: 73 DGDQTALHRATVVGNTEIIAALIHEG 98
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 123 bits (296), Expect = 8e-28
Identities = 69/214 (32%), Positives = 103/214 (48%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AAR H D+ ++L G+ + +E +TPLH A+ G+ +A L + G +V
Sbjct: 3 LHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKN 62
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ PL A+ + HD+ L EH A L A K G ALHLA + ++V LL+ G
Sbjct: 63 REGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGC 122
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
D ++G TPLH+A + + L E + K G TPLH+AA ++
Sbjct: 123 FVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRY 182
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
L GA A + G T LA + H + LL
Sbjct: 183 LCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 216
Score = 101 bits (241), Expect = 4e-21
Identities = 65/185 (35%), Positives = 88/185 (47%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ETP+H AA H + + L G V K RE +TPL AS G DI L +HGAD+
Sbjct: 33 ETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 92
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A D + LH+A ++ +V L+ + + G T LH+A K GN+ + L
Sbjct: 93 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 152
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
D + K G TPLH+AA V L GA +A+ +G T + AR Q E
Sbjct: 153 ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDL-ARSEQHEH 211
Query: 553 AATLL 567
A LL
Sbjct: 212 VAGLL 216
Score = 92.7 bits (220), Expect = 1e-18
Identities = 53/150 (35%), Positives = 74/150 (49%)
Frame = +1
Query: 220 LHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAG 399
LH+AA+ + DVA L + K+ T LH AA +G+ VA L G +
Sbjct: 3 LHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKN 62
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
+ G TPL A+ + L E GAD A K+GH LH+A R+ QME TLL G
Sbjct: 63 REGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGC 122
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + + G TPLH+A + G+ + L E
Sbjct: 123 FVDYQDRHGNTPLHVACKDGNMPIVVALCE 152
Score = 81.0 bits (191), Expect = 4e-15
Identities = 46/120 (38%), Positives = 63/120 (52%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
ALH+AA+YG+ VA LL + G+ P+ K TPLH AA + +VA L E G +
Sbjct: 2 ALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIK 61
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ G TPL A+ + + L E+GA NA K G LHLA ++ E+ LL G
Sbjct: 62 NREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQG 121
Score = 77.8 bits (183), Expect = 4e-14
Identities = 50/152 (32%), Positives = 70/152 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GETP+ A+ + DI+ L +GA + A ++ LH+A R +++ LL G V
Sbjct: 65 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFV 124
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PLH+A K N + AL E N L + K G T LHLAA G L V L
Sbjct: 125 DYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLC 184
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
GA+ + +G T +A + VA L
Sbjct: 185 LMGASVEALTTDGKTAEDLARSEQHEHVAGLL 216
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 122 bits (295), Expect = 1e-27
Identities = 70/219 (31%), Positives = 104/219 (47%), Gaps = 1/219 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
GE +H+AAR H D+ ++ A + ++ +E +TPLH A+ G +A L + G +
Sbjct: 445 GEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAWHGYYSVAKALCEAGCN 504
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V + PL A+ + HD+ L EH A L A K G ALHLA + ++V L
Sbjct: 505 VNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTL 564
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L+ G D ++G TPLH+A + + L E + K G TPLH+AA +
Sbjct: 565 LSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGIL 624
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ L GA A + G T LA + H + LL
Sbjct: 625 DVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 663
Score = 111 bits (267), Expect = 3e-24
Identities = 67/221 (30%), Positives = 109/221 (49%), Gaps = 1/221 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+ +AA + I+++L++ G+ ++ + + ++ A+R G+VD L ++ +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT-TKKGFTALHLAAKYGNLKVANLL 366
LH+AA+ + DVA +A + + TK+ T LH AA +G VA L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAWHGYYSVAKAL 498
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
G + + G TPL A+ + L E GAD A K+GH LH+A R+ QM
Sbjct: 499 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQM 558
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
E TLL G + + + G TPLH+A + G+ + L E
Sbjct: 559 EVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 599
Score = 101 bits (242), Expect = 3e-21
Identities = 65/187 (34%), Positives = 91/187 (48%), Gaps = 1/187 (0%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
PL IA+ GN+ I LL++ G+ + N ++ AA+ + D L E+ PL
Sbjct: 382 PLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVK 441
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAA-PDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
K G ALH+AA+YG+ VA + A A P K TPLH AA + +VA L E
Sbjct: 442 DKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAWHGYYSVAKALCEA 501
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
G + + G TPL A+ + + L E+GA NA K G LHLA ++ E+
Sbjct: 502 GCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVI 561
Query: 655 ALLLEGG 675
LL G
Sbjct: 562 KTLLSQG 568
Score = 99.1 bits (236), Expect = 1e-20
Identities = 65/189 (34%), Positives = 89/189 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T ETP+H AA + + + L G V K RE +TPL AS G DI L +HG
Sbjct: 476 TKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHG 535
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD+ A D + LH+A ++ +V L+ + + G T LH+A K GN+ +
Sbjct: 536 ADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV 595
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L D + K G TPLH+AA V L GA +A+ +G T + AR
Sbjct: 596 ALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDL-ARSE 654
Query: 541 QMETAATLL 567
Q E A LL
Sbjct: 655 QHEHVAGLL 663
Score = 56.8 bits (131), Expect = 8e-08
Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 1/134 (0%)
Frame = +1
Query: 277 NAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
N + K G L +AA GN+++ LL+ G+ D K G ++ AA++
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETA-ATLLEYGALTNAESKAGFTPLHLAAQ 633
L E K+G LH+AAR + A T + + +K TPLH AA
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAW 488
Query: 634 QGHTEMCALLLEGG 675
G+ + L E G
Sbjct: 489 HGYYSVAKALCEAG 502
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 118 bits (285), Expect = 2e-26
Identities = 74/219 (33%), Positives = 105/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++ LL GAAV++ E +T L IAS GNV++ LL G D
Sbjct: 95 GRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 154
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ PLH+AA + + + ALIE A G LA++ G+ +LL
Sbjct: 155 NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILL 214
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ + DQ G +G L +AA + + L GAD +G L+I A +NQ+
Sbjct: 215 ENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLT 274
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LE GA A G T LH++ QGH EM +L+
Sbjct: 275 MAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 313
Score = 118 bits (285), Expect = 2e-26
Identities = 70/222 (31%), Positives = 117/222 (52%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P LA++ H D ++ILL N + ++ + + + L +A+ G+ DI LL HGADV
Sbjct: 194 GRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADV 253
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
AD L+I A ++ +A +E+ A + A+ +G TALH++ G++++ +L+
Sbjct: 254 NCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI 313
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A+ A + A + L AA V L+E GA G T L IAA++ ++
Sbjct: 314 AYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHID 373
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LLE+GA N + G T + +AA+ GH+++ LL + G
Sbjct: 374 VVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYG 415
Score = 112 bits (270), Expect = 1e-24
Identities = 75/213 (35%), Positives = 103/213 (48%), Gaps = 5/213 (2%)
Frame = +1
Query: 46 HTDIIRILLRNGAAVEAKARERQTPLHIASRL-----GNVDIAVLLLQHGADVRAITADH 210
H +I+ LL +GA V + + +T L +A+ G+ + LL+ GA+V D
Sbjct: 3 HREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDG 62
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
PL +AA + + DV L+E A + T G T L AA G+ V N LL GAA D
Sbjct: 63 MTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVD 122
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
G T L IA+ V TLL++G D G TPLH+AA + L+E
Sbjct: 123 SIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIE 182
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
GA TN G P LA+Q+GH + +LLE
Sbjct: 183 QGARTNEIDNDGRIPFILASQEGHYDCVQILLE 215
Score = 109 bits (262), Expect = 1e-23
Identities = 69/187 (36%), Positives = 95/187 (50%), Gaps = 5/187 (2%)
Frame = +1
Query: 139 LGNVDIAVLLLQHGADVRAITADHYNPLHIAA-----KQHNHDVAAALIEHNAPLTATTK 303
+G+ +I LL HGA+V D L +AA + + V + LI+ A + K
Sbjct: 1 MGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDK 60
Query: 304 KGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
G T L +AA G++ V +LLL GA D NG TPL AA +V TLL GA
Sbjct: 61 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 120
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
++ G T L IA+ + +E TLL+ G N AG+TPLH+AA +GH +C L
Sbjct: 121 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 180
Query: 664 LEGGPGT 684
+E G T
Sbjct: 181 IEQGART 187
Score = 108 bits (259), Expect = 2e-23
Identities = 67/222 (30%), Positives = 109/222 (49%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A+ + +++R LL G + TPLH+A+ G+ I L++ GA
Sbjct: 128 GRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 187
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I D P +A+++ ++D L+E+ + + G AL +AA G+ + LL
Sbjct: 188 NEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLF 247
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+HGA + +G L+I A +Q +A LE GA+ +A G T LH++ + ME
Sbjct: 248 SHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHME 307
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ Y A NA + L AA QGH ++ LL+E G
Sbjct: 308 MVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHG 349
Score = 106 bits (254), Expect = 9e-23
Identities = 63/214 (29%), Positives = 104/214 (48%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A H ++ +L+ GA V+ ++ TPL +A+ G+VD+ LLL+ GADV +
Sbjct: 37 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 96
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
PL AA + V L+ A + + +G T L +A+ GN++V LL G +
Sbjct: 97 TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 156
Query: 394 AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEY 573
G TPLH+AA + + L+E+GA + +G P +A+++ + LLE
Sbjct: 157 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN 216
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + G L +AA +GH ++ LL G
Sbjct: 217 KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHG 250
Score = 106 bits (254), Expect = 9e-23
Identities = 62/222 (27%), Positives = 104/222 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+H+AA H I L+ GA + + P +AS+ G+ D +LL++ +++
Sbjct: 161 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 220
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D N L +AA + + D+ L H A + G L++ A L +A L
Sbjct: 221 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 280
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA + + G T LH++ + L+ AD A + L AA + ++
Sbjct: 281 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 340
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+E+GA+ + G T L +AAQ+GH ++ +LLE G
Sbjct: 341 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHG 382
Score = 105 bits (253), Expect = 1e-22
Identities = 65/209 (31%), Positives = 105/209 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +AA H DI+ +L +GA V K + + L+I + + +A L++GA+V
Sbjct: 227 GRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANV 286
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A A+ LH++ Q + ++ LI ++A + A + +AL AA G++KV LL+
Sbjct: 287 EASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLI 346
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA D G T L IAAQ V LLE GAD + G T + +AA+ +
Sbjct: 347 EHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQ 406
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
L +YGA ++ + +P+H Q+
Sbjct: 407 IIKLLEKYGA--SSLNGCSPSPVHTMEQK 433
Score = 100 bits (240), Expect = 5e-21
Identities = 62/226 (27%), Positives = 102/226 (45%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA H D++ +LL GA V+ +TPL A+ +G+ + LL GA V
Sbjct: 62 GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 121
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+I ++ L IA+ Q N +V L++ G+T LH+AA G+ + L+
Sbjct: 122 DSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALI 181
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ +G P +A+Q LLE ++ +G L +AA + +
Sbjct: 182 EQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRD 241
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
L +GA N + G L++ A + M LE G +
Sbjct: 242 IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 287
>BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS
box-containing 2 protein.
Length = 587
Score = 118 bits (283), Expect = 3e-26
Identities = 69/222 (31%), Positives = 112/222 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T++ ET V+LA H D + LL+ GA + + R+TPL+ A N + +L+QH
Sbjct: 121 TLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHN 180
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD + LH + +++ +V L+ A + + G T L +AA+ G L+
Sbjct: 181 ADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALR 240
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L +GA + + + L+ A + + + V LL +GADA K+G PLHIA++K
Sbjct: 241 FLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKG 300
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL + T ++G +PLHLAA++ H E+ LL
Sbjct: 301 NYRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEVLEALL 341
Score = 113 bits (271), Expect = 8e-25
Identities = 64/220 (29%), Positives = 111/220 (50%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G P+H AA +++L R ++ + + +T +++A+ G++D + LLQ GA+
Sbjct: 90 GWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAE 149
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
PL+ A ++ N + L++HNA +G+TALH + +L+V +L
Sbjct: 150 PDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQIL 209
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
++ GA + G+TPL +AAQ Q L + GAD A + + L+ A +
Sbjct: 210 VSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHE 269
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
E LL GA N +K G PLH+A+++G+ + +LL
Sbjct: 270 EVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Score = 77.4 bits (182), Expect = 5e-14
Identities = 53/220 (24%), Positives = 97/220 (44%), Gaps = 1/220 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRA 195
P+ A + + ++ +++ G + +E PLH A+ G V + VL + +
Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQ 119
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T +++A + + D +L++ A + K T L+ A + N + +L+ H
Sbjct: 120 RTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQH 179
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + G T LH + + V L+ GA ++ G TPL +AA+ Q+E
Sbjct: 180 NADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEAL 239
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L +YGA N ++ + L+ A + H E+ LL G
Sbjct: 240 RFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQG 279
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/203 (27%), Positives = 98/203 (48%), Gaps = 9/203 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA++ + +R L + GA + +A + + L+ A + + ++ LL GAD
Sbjct: 223 GITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADA 282
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PLHIA+K+ N+ + L+ + T + G + LHLAA+ + +V LL
Sbjct: 283 NKTNKDGLLPLHIASKKGNYRIVQMLLPVTSR-TRIRRSGVSPLHLAAERNHDEVLEALL 341
Query: 370 AHG------AAPDQAG---KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
+ AP++A + L+ A + LL+ GAD ++ +PL
Sbjct: 342 SARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLL 398
Query: 523 IAARKNQMETAATLLEYGALTNA 591
+A R + T LL++GA +A
Sbjct: 399 VAIRHGCLRTMQLLLDHGANIDA 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL-LAHGAAPD 390
+PL A K + + +I+ L K+G+ LH AA YG + +L A+ D
Sbjct: 59 DPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 118
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
Q T +++A +LL+ GA+ K+ TPL+ A + E L++
Sbjct: 119 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A TN G+T LH + + E+ +L+ GG
Sbjct: 179 HNADTNHRCNRGWTALHESVSRNDLEVMQILVSGG 213
Score = 32.3 bits (70), Expect = 1.9
Identities = 22/68 (32%), Positives = 35/68 (51%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R + ++ A N+ +LL++GA R+ +PL +A R G + LLL HGA+
Sbjct: 362 RRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGAN 418
Query: 187 VRAITADH 210
+ A A H
Sbjct: 419 IDAYIATH 426
Score = 31.1 bits (67), Expect = 4.3
Identities = 18/57 (31%), Positives = 25/57 (43%)
Frame = +1
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
PL A + E T+++ G +K G+ PLH AA G +L PGT
Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT 116
>AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein
protein.
Length = 587
Score = 118 bits (283), Expect = 3e-26
Identities = 69/222 (31%), Positives = 112/222 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T++ ET V+LA H D + LL+ GA + + R+TPL+ A N + +L+QH
Sbjct: 121 TLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHN 180
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD + LH + +++ +V L+ A + + G T L +AA+ G L+
Sbjct: 181 ADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALR 240
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L +GA + + + L+ A + + + V LL +GADA K+G PLHIA++K
Sbjct: 241 FLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKG 300
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL + T ++G +PLHLAA++ H E+ LL
Sbjct: 301 NYRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEVLEALL 341
Score = 113 bits (271), Expect = 8e-25
Identities = 64/220 (29%), Positives = 111/220 (50%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G P+H AA +++L R ++ + + +T +++A+ G++D + LLQ GA+
Sbjct: 90 GWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAE 149
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
PL+ A ++ N + L++HNA +G+TALH + +L+V +L
Sbjct: 150 PDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQIL 209
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
++ GA + G+TPL +AAQ Q L + GAD A + + L+ A +
Sbjct: 210 VSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHE 269
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
E LL GA N +K G PLH+A+++G+ + +LL
Sbjct: 270 EVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Score = 77.4 bits (182), Expect = 5e-14
Identities = 53/220 (24%), Positives = 97/220 (44%), Gaps = 1/220 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRA 195
P+ A + + ++ +++ G + +E PLH A+ G V + VL + +
Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQ 119
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T +++A + + D +L++ A + K T L+ A + N + +L+ H
Sbjct: 120 RTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQH 179
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + G T LH + + V L+ GA ++ G TPL +AA+ Q+E
Sbjct: 180 NADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEAL 239
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L +YGA N ++ + L+ A + H E+ LL G
Sbjct: 240 RFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQG 279
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/203 (27%), Positives = 98/203 (48%), Gaps = 9/203 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA++ + +R L + GA + +A + + L+ A + + ++ LL GAD
Sbjct: 223 GITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADA 282
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PLHIA+K+ N+ + L+ + T + G + LHLAA+ + +V LL
Sbjct: 283 NKTNKDGLLPLHIASKKGNYRIVQMLLPVTSR-TRIRRSGVSPLHLAAERNHDEVLEALL 341
Query: 370 AHG------AAPDQAG---KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
+ AP++A + L+ A + LL+ GAD ++ +PL
Sbjct: 342 SARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLL 398
Query: 523 IAARKNQMETAATLLEYGALTNA 591
+A R + T LL++GA +A
Sbjct: 399 VAIRHGCLRTMQLLLDHGANIDA 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL-LAHGAAPD 390
+PL A K + + +I+ L K+G+ LH AA YG + +L A+ D
Sbjct: 59 DPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 118
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
Q T +++A +LL+ GA+ K+ TPL+ A + E L++
Sbjct: 119 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A TN G+T LH + + E+ +L+ GG
Sbjct: 179 HNADTNHRCNRGWTALHESVSRNDLEVMQILVSGG 213
Score = 32.3 bits (70), Expect = 1.9
Identities = 22/68 (32%), Positives = 35/68 (51%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R + ++ A N+ +LL++GA R+ +PL +A R G + LLL HGA+
Sbjct: 362 RRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGAN 418
Query: 187 VRAITADH 210
+ A A H
Sbjct: 419 IDAYIATH 426
Score = 31.1 bits (67), Expect = 4.3
Identities = 18/57 (31%), Positives = 25/57 (43%)
Frame = +1
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
PL A + E T+++ G +K G+ PLH AA G +L PGT
Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT 116
>AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteining
protein with a SOCS box-2 protein.
Length = 587
Score = 118 bits (283), Expect = 3e-26
Identities = 69/222 (31%), Positives = 112/222 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T++ ET V+LA H D + LL+ GA + + R+TPL+ A N + +L+QH
Sbjct: 121 TLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHN 180
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD + LH + +++ +V L+ A + + G T L +AA+ G L+
Sbjct: 181 ADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALR 240
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L +GA + + + L+ A + + + V LL +GADA K+G PLHIA++K
Sbjct: 241 FLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKG 300
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL + T ++G +PLHLAA++ H E+ LL
Sbjct: 301 NYRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEVLEALL 341
Score = 113 bits (271), Expect = 8e-25
Identities = 64/220 (29%), Positives = 111/220 (50%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G P+H AA +++L R ++ + + +T +++A+ G++D + LLQ GA+
Sbjct: 90 GWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAE 149
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
PL+ A ++ N + L++HNA +G+TALH + +L+V +L
Sbjct: 150 PDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQIL 209
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
++ GA + G+TPL +AAQ Q L + GAD A + + L+ A +
Sbjct: 210 VSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHE 269
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
E LL GA N +K G PLH+A+++G+ + +LL
Sbjct: 270 EVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Score = 77.4 bits (182), Expect = 5e-14
Identities = 53/220 (24%), Positives = 97/220 (44%), Gaps = 1/220 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRA 195
P+ A + + ++ +++ G + +E PLH A+ G V + VL + +
Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQ 119
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
T +++A + + D +L++ A + K T L+ A + N + +L+ H
Sbjct: 120 RTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQH 179
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
A + G T LH + + V L+ GA ++ G TPL +AA+ Q+E
Sbjct: 180 NADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEAL 239
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L +YGA N ++ + L+ A + H E+ LL G
Sbjct: 240 RFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQG 279
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/203 (27%), Positives = 98/203 (48%), Gaps = 9/203 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ +AA++ + +R L + GA + +A + + L+ A + + ++ LL GAD
Sbjct: 223 GITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADA 282
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PLHIA+K+ N+ + L+ + T + G + LHLAA+ + +V LL
Sbjct: 283 NKTNKDGLLPLHIASKKGNYRIVQMLLPVTSR-TRIRRSGVSPLHLAAERNHDEVLEALL 341
Query: 370 AHG------AAPDQAG---KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
+ AP++A + L+ A + LL+ GAD ++ +PL
Sbjct: 342 SARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLL 398
Query: 523 IAARKNQMETAATLLEYGALTNA 591
+A R + T LL++GA +A
Sbjct: 399 VAIRHGCLRTMQLLLDHGANIDA 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL-LAHGAAPD 390
+PL A K + + +I+ L K+G+ LH AA YG + +L A+ D
Sbjct: 59 DPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 118
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
Q T +++A +LL+ GA+ K+ TPL+ A + E L++
Sbjct: 119 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A TN G+T LH + + E+ +L+ GG
Sbjct: 179 HNADTNHRCNRGWTALHESVSRNDLEVMQILVSGG 213
Score = 32.3 bits (70), Expect = 1.9
Identities = 22/68 (32%), Positives = 35/68 (51%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R + ++ A N+ +LL++GA R+ +PL +A R G + LLL HGA+
Sbjct: 362 RRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGAN 418
Query: 187 VRAITADH 210
+ A A H
Sbjct: 419 IDAYIATH 426
Score = 31.1 bits (67), Expect = 4.3
Identities = 18/57 (31%), Positives = 25/57 (43%)
Frame = +1
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
PL A + E T+++ G +K G+ PLH AA G +L PGT
Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT 116
>AL158217-11|CAI22163.1| 854|Homo sapiens espin protein.
Length = 854
Score = 116 bits (280), Expect = 7e-26
Identities = 79/227 (34%), Positives = 112/227 (49%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA- 183
G TP H A+ H ++ LL + G V+ K T LH+A+R G+ ++ LL HG
Sbjct: 70 GATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGG 129
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP-LTATTKKGFTALHLAAKYGNLKVAN 360
D A T P+H AA + + L+EH + A TK G T L+LA + G+L+V
Sbjct: 130 DPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQ 189
Query: 361 LLLAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAAR 534
L+ GA P +GMTPLH AAQ V L+ K+G T +H AA
Sbjct: 190 YLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAAS 249
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + + LL +G +A+ G TPLH AA+ G E C +L+ G
Sbjct: 250 RGHTKVLSWLLLHGGEISADLWGG-TPLHDAAENGELECCQILVVNG 295
Score = 105 bits (252), Expect = 2e-22
Identities = 80/226 (35%), Positives = 112/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGA-AVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVR 192
PVH AARA +R L+ A A+AR TP H AS G++ + LL Q G V+
Sbjct: 39 PVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQ 98
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + +V L+ H TA T G +H AA G+ LL+
Sbjct: 99 DKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLV 158
Query: 370 AH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQ 543
H + KNG TPL++A Q V L+++ GAD A A +G TPLH AA+
Sbjct: 159 EHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGH 218
Query: 544 METAATLLEYGALTNAE-SKAGFTPLHLAAQQGHTEMCA-LLLEGG 675
L+ ++ +E K G T +H AA +GHT++ + LLL GG
Sbjct: 219 SPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGG 264
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/216 (30%), Positives = 104/216 (48%), Gaps = 4/216 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQT-PLHIASRLGNVDIAVLLLQHGAD 186
G T +HLAAR H +++ LL +G A + P+H A+ G+ LL++H +
Sbjct: 104 GATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPE 163
Query: 187 -VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T + PL++A ++ + +V L++ A A G T LH AA+ G+ V
Sbjct: 164 GVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIV 223
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L++ + + K+G T +H AA V + LL G + A G TPLH AA
Sbjct: 224 WLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGG-TPLHDAAEN 282
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
++E L+ GA + + G+T L+ GH+
Sbjct: 283 GELECCQILVVNGAELDVRDRDGYTAADLSDFNGHS 318
Score = 87.4 bits (207), Expect = 5e-17
Identities = 70/218 (32%), Positives = 100/218 (45%), Gaps = 6/218 (2%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQT-PLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR D++R L G + P+H A+R G + L++ A A A
Sbjct: 9 AARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARAR 68
Query: 208 H-YNPLHIA-AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ P H A A H + L + + G T LHLAA++G+ +V N LL HG
Sbjct: 69 NGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGG 128
Query: 382 A-PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQMETA 555
P A G P+H AA L+E + A KNG TPL++A ++ +E
Sbjct: 129 GDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVT 188
Query: 556 ATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L+ E GA +A + G TPLH AAQ GH+ + L+
Sbjct: 189 QYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLV 226
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/121 (34%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +1
Query: 328 AAKYGNLKVANLLLAHGA-APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA-DAKAVAK 501
AA+ G L V L A G P P+H AA+ + L+E+ A A A A+
Sbjct: 9 AARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARAR 68
Query: 502 NGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
NG TP H A+ + LL G + +G T LHLAA+ GH E+ LL G
Sbjct: 69 NGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGG 128
Query: 679 G 681
G
Sbjct: 129 G 129
>AL031848-3|CAI19773.1| 854|Homo sapiens espin protein.
Length = 854
Score = 116 bits (280), Expect = 7e-26
Identities = 79/227 (34%), Positives = 112/227 (49%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA- 183
G TP H A+ H ++ LL + G V+ K T LH+A+R G+ ++ LL HG
Sbjct: 70 GATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGG 129
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP-LTATTKKGFTALHLAAKYGNLKVAN 360
D A T P+H AA + + L+EH + A TK G T L+LA + G+L+V
Sbjct: 130 DPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQ 189
Query: 361 LLLAH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAAR 534
L+ GA P +GMTPLH AAQ V L+ K+G T +H AA
Sbjct: 190 YLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAAS 249
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + + LL +G +A+ G TPLH AA+ G E C +L+ G
Sbjct: 250 RGHTKVLSWLLLHGGEISADLWGG-TPLHDAAENGELECCQILVVNG 295
Score = 105 bits (252), Expect = 2e-22
Identities = 80/226 (35%), Positives = 112/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGA-AVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVR 192
PVH AARA +R L+ A A+AR TP H AS G++ + LL Q G V+
Sbjct: 39 PVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQ 98
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
LH+AA+ + +V L+ H TA T G +H AA G+ LL+
Sbjct: 99 DKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLV 158
Query: 370 AH-GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GADAKAVAKNGHTPLHIAARKNQ 543
H + KNG TPL++A Q V L+++ GAD A A +G TPLH AA+
Sbjct: 159 EHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGH 218
Query: 544 METAATLLEYGALTNAE-SKAGFTPLHLAAQQGHTEMCA-LLLEGG 675
L+ ++ +E K G T +H AA +GHT++ + LLL GG
Sbjct: 219 SPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGG 264
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/216 (30%), Positives = 104/216 (48%), Gaps = 4/216 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQT-PLHIASRLGNVDIAVLLLQHGAD 186
G T +HLAAR H +++ LL +G A + P+H A+ G+ LL++H +
Sbjct: 104 GATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPE 163
Query: 187 -VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVAN 360
V A T + PL++A ++ + +V L++ A A G T LH AA+ G+ V
Sbjct: 164 GVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIV 223
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L++ + + K+G T +H AA V + LL G + A G TPLH AA
Sbjct: 224 WLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGG-TPLHDAAEN 282
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
++E L+ GA + + G+T L+ GH+
Sbjct: 283 GELECCQILVVNGAELDVRDRDGYTAADLSDFNGHS 318
Score = 87.4 bits (207), Expect = 5e-17
Identities = 70/218 (32%), Positives = 100/218 (45%), Gaps = 6/218 (2%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQT-PLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR D++R L G + P+H A+R G + L++ A A A
Sbjct: 9 AARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARAR 68
Query: 208 H-YNPLHIA-AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ P H A A H + L + + G T LHLAA++G+ +V N LL HG
Sbjct: 69 NGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGG 128
Query: 382 A-PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQMETA 555
P A G P+H AA L+E + A KNG TPL++A ++ +E
Sbjct: 129 GDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVT 188
Query: 556 ATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L+ E GA +A + G TPLH AAQ GH+ + L+
Sbjct: 189 QYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLV 226
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/121 (34%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +1
Query: 328 AAKYGNLKVANLLLAHGA-APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA-DAKAVAK 501
AA+ G L V L A G P P+H AA+ + L+E+ A A A A+
Sbjct: 9 AARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARAR 68
Query: 502 NGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
NG TP H A+ + LL G + +G T LHLAA+ GH E+ LL G
Sbjct: 69 NGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGG 128
Query: 679 G 681
G
Sbjct: 129 G 129
>BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 116 bits (278), Expect = 1e-25
Identities = 74/216 (34%), Positives = 106/216 (49%), Gaps = 4/216 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+ VH AA + +I +L R A + A+ + RQTPLHIA G++ + LL G
Sbjct: 497 GDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ PLH A + D+ A L+E A +T T GF ALH AA GN +LL
Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616
Query: 370 AHGAAP---DQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAARK 537
+ P D+ +G T LH+AA + VA L+ +G A+ N T LH+A +
Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 676
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
+ L+ GA + + K G TPLH A + HT
Sbjct: 677 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRH-HT 711
Score = 99.5 bits (237), Expect = 1e-20
Identities = 73/224 (32%), Positives = 98/224 (43%), Gaps = 3/224 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E V AA + + +L R V + T + AS+ G+VDI LLL+ DV
Sbjct: 433 EELVKAAANGDVAKVEDLLKRPDVDVNGQCAGH-TAMQAASQNGHVDILKLLLKQNVDVE 491
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A D +H AA V L +A L A K+ T LH+A G+L+V LL
Sbjct: 492 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 551
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK---NQ 543
G P G TPLH A + + LLE GAD NG LH AA + +
Sbjct: 552 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA 611
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M + L + + + G+T LHLAA H E+ LL+ G
Sbjct: 612 MRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655
Score = 98.3 bits (234), Expect = 3e-20
Identities = 64/184 (34%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +TP+H+A H +++ LL G + E TPLH A DI +LL+ GAD
Sbjct: 529 RRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 588
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKK--GFTALHLAAKYGNLKVA 357
V + +N LH AA + N L+ P KK G+TALHLAA +++VA
Sbjct: 589 VTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVA 648
Query: 358 NLLLAHGAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LL+ G A D N T LH+A + + L+ GA K+G TPLH A R
Sbjct: 649 ELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALR 708
Query: 535 KNQM 546
+ +
Sbjct: 709 HHTL 712
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/227 (29%), Positives = 106/227 (46%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-AD 186
G T + A++ H DI+++LL+ VEA+ ++ +H A+ G+ + +L G AD
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGDEGAVIEVLHRGSAD 522
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ A PLHIA + + V L++ + +G T LH A + +L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK---NGHTPLHIAARK 537
L GA NG LH AA + LL K V + +G+T LH+AA
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALN 642
Query: 538 NQMETAATLLEYG-ALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N +E A L+ G A + ++ T LHLA ++ HT++ LL+ G
Sbjct: 643 NHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAG 689
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/174 (34%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +1
Query: 163 LLLQHGADVRAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKY 339
LL + DV A H AA Q+ H D+ L++ N + A K G A+H AA +
Sbjct: 450 LLKRPDVDVNGQCAGH--TAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-F 506
Query: 340 GNLKVANLLLAHGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
G+ +L G+A A K TPLHIA V TLL+ G G TP
Sbjct: 507 GDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTP 566
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
LH A K + + A LLE GA + GF LH AA +G+ +LL P
Sbjct: 567 LHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLP 620
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 12/195 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
G +H AA + +R+LL V+ K + T LH+A+ +V++A LL+ G
Sbjct: 596 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655
Query: 181 -ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A++ + LH+A ++ + + L+ A L K G T LH A ++ L
Sbjct: 656 NANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQL 715
Query: 358 NLL--LAHGAAPDQAGKNGMTPLHI------AAQYDQQAVATTLLEKGADAKAVAKNGHT 513
L + D A + L + A + ++A L GAD K G +
Sbjct: 716 RQLQDMQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQS 775
Query: 514 PLHIAARKNQMETAA 558
PL + N + A
Sbjct: 776 PLDLCPDPNLCKALA 790
Score = 45.2 bits (102), Expect = 2e-04
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V +T +HLA HT I+R+L+R GA ++ + ++ TPLH A R + + LQ
Sbjct: 664 VNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLS-QLRQLQDMQ 722
Query: 184 DVRAITA---DHYNPLHI------AAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
DV + A N L + A K+ +A L + A L+ KKG + L L
Sbjct: 723 DVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 779
>BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 116 bits (278), Expect = 1e-25
Identities = 74/216 (34%), Positives = 106/216 (49%), Gaps = 4/216 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+ VH AA + +I +L R A + A+ + RQTPLHIA G++ + LL G
Sbjct: 497 GDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ PLH A + D+ A L+E A +T T GF ALH AA GN +LL
Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616
Query: 370 AHGAAP---DQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAARK 537
+ P D+ +G T LH+AA + VA L+ +G A+ N T LH+A +
Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 676
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
+ L+ GA + + K G TPLH A + HT
Sbjct: 677 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRH-HT 711
Score = 99.5 bits (237), Expect = 1e-20
Identities = 73/224 (32%), Positives = 98/224 (43%), Gaps = 3/224 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E V AA + + +L R V + T + AS+ G+VDI LLL+ DV
Sbjct: 433 EELVKAAANGDVAKVEDLLKRPDVDVNGQCAGH-TAMQAASQNGHVDILKLLLKQNVDVE 491
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A D +H AA V L +A L A K+ T LH+A G+L+V LL
Sbjct: 492 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 551
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK---NQ 543
G P G TPLH A + + LLE GAD NG LH AA + +
Sbjct: 552 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA 611
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M + L + + + G+T LHLAA H E+ LL+ G
Sbjct: 612 MRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655
Score = 98.3 bits (234), Expect = 3e-20
Identities = 64/184 (34%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +TP+H+A H +++ LL G + E TPLH A DI +LL+ GAD
Sbjct: 529 RRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 588
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKK--GFTALHLAAKYGNLKVA 357
V + +N LH AA + N L+ P KK G+TALHLAA +++VA
Sbjct: 589 VTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVA 648
Query: 358 NLLLAHGAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LL+ G A D N T LH+A + + L+ GA K+G TPLH A R
Sbjct: 649 ELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALR 708
Query: 535 KNQM 546
+ +
Sbjct: 709 HHTL 712
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/227 (29%), Positives = 106/227 (46%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-AD 186
G T + A++ H DI+++LL+ VEA+ ++ +H A+ G+ + +L G AD
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGDEGAVIEVLHRGSAD 522
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ A PLHIA + + V L++ + +G T LH A + +L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK---NGHTPLHIAARK 537
L GA NG LH AA + LL K V + +G+T LH+AA
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALN 642
Query: 538 NQMETAATLLEYG-ALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N +E A L+ G A + ++ T LHLA ++ HT++ LL+ G
Sbjct: 643 NHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAG 689
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/174 (34%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +1
Query: 163 LLLQHGADVRAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKY 339
LL + DV A H AA Q+ H D+ L++ N + A K G A+H AA +
Sbjct: 450 LLKRPDVDVNGQCAGH--TAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-F 506
Query: 340 GNLKVANLLLAHGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
G+ +L G+A A K TPLHIA V TLL+ G G TP
Sbjct: 507 GDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTP 566
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
LH A K + + A LLE GA + GF LH AA +G+ +LL P
Sbjct: 567 LHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLP 620
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 12/195 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
G +H AA + +R+LL V+ K + T LH+A+ +V++A LL+ G
Sbjct: 596 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655
Query: 181 -ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A++ + LH+A ++ + + L+ A L K G T LH A ++ L
Sbjct: 656 NANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQL 715
Query: 358 NLL--LAHGAAPDQAGKNGMTPLHI------AAQYDQQAVATTLLEKGADAKAVAKNGHT 513
L + D A + L + A + ++A L GAD K G +
Sbjct: 716 RQLQDMQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQS 775
Query: 514 PLHIAARKNQMETAA 558
PL + N + A
Sbjct: 776 PLDLCPDPNLCKALA 790
Score = 45.2 bits (102), Expect = 2e-04
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V +T +HLA HT I+R+L+R GA ++ + ++ TPLH A R + + LQ
Sbjct: 664 VNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLS-QLRQLQDMQ 722
Query: 184 DVRAITA---DHYNPLHI------AAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
DV + A N L + A K+ +A L + A L+ KKG + L L
Sbjct: 723 DVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 779
>BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS
box-containing 9 protein.
Length = 294
Score = 116 bits (278), Expect = 1e-25
Identities = 72/221 (32%), Positives = 110/221 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA H +R L+ G AV + +PLH A G++ +LL+HGA V
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+TAD + PL A + D L++H A + + + +H AA+ G+++ N L+A+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLIAY 156
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G D + TPL++A + Q+A LLE GAD K +PLH AR E A
Sbjct: 157 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ-GKGQDSPLHAVARTASEELA 215
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
L+++GA T A++ G P+ L + L EG P
Sbjct: 216 CLLMDFGADTQAKNAEGKRPVELVPPESPLAQLFLEREGPP 256
Score = 86.2 bits (204), Expect = 1e-16
Identities = 60/191 (31%), Positives = 88/191 (46%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
+P+H A+ G+ L+ G V ITADH +PLH A + L++H A +
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T T L A G+ NLLL HGA+ Q + +P+H AA+ +L+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAY 156
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
G + + TPL++A Q LLE GA N + K +PLH A+ E+
Sbjct: 157 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASEELA 215
Query: 655 ALLLEGGPGTQ 687
LL++ G TQ
Sbjct: 216 CLLMDFGADTQ 226
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Frame = +1
Query: 211 YNPLHIAAKQHNHDVAAA-LIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
++P+H AA H H ++ LI + T + LH A G+L +LL HGA
Sbjct: 37 WSPMHEAAI-HGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQV 95
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+ + TPL A LL+ GA + + +P+H AAR+ +E +L+
Sbjct: 96 NGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLI 154
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
YG + + TPL+LA + LLE G
Sbjct: 155 AYGGNIDHKISHLGTPLYLACENQQRACVKKLLESG 190
Score = 58.4 bits (135), Expect = 2e-08
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Frame = +1
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
PL ++ +H AA +G+ L++ G A + + ++PLH A +
Sbjct: 28 PLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKI 87
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ GA V + HTPL A + LL++GA ES +P+H AA++GH
Sbjct: 88 LLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGH 146
Query: 643 TE-MCALLLEGG 675
E + +L+ GG
Sbjct: 147 VECVNSLIAYGG 158
>AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein.
Length = 1006
Score = 116 bits (278), Expect = 1e-25
Identities = 74/216 (34%), Positives = 106/216 (49%), Gaps = 4/216 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+ VH AA + +I +L R A + A+ + RQTPLHIA G++ + LL G
Sbjct: 497 GDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ PLH A + D+ A L+E A +T T GF ALH AA GN +LL
Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 616
Query: 370 AHGAAP---DQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAARK 537
+ P D+ +G T LH+AA + VA L+ +G A+ N T LH+A +
Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 676
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
+ L+ GA + + K G TPLH A + HT
Sbjct: 677 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRH-HT 711
Score = 99.5 bits (237), Expect = 1e-20
Identities = 73/224 (32%), Positives = 98/224 (43%), Gaps = 3/224 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E V AA + + +L R V + T + AS+ G+VDI LLL+ DV
Sbjct: 433 EELVKAAANGDVAKVEDLLKRPDVDVNGQCAGH-TAMQAASQNGHVDILKLLLKQNVDVE 491
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A D +H AA V L +A L A K+ T LH+A G+L+V LL
Sbjct: 492 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 551
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK---NQ 543
G P G TPLH A + + LLE GAD NG LH AA + +
Sbjct: 552 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA 611
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M + L + + + G+T LHLAA H E+ LL+ G
Sbjct: 612 MRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655
Score = 98.3 bits (234), Expect = 3e-20
Identities = 64/184 (34%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +TP+H+A H +++ LL G + E TPLH A DI +LL+ GAD
Sbjct: 529 RRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 588
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKK--GFTALHLAAKYGNLKVA 357
V + +N LH AA + N L+ P KK G+TALHLAA +++VA
Sbjct: 589 VTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVA 648
Query: 358 NLLLAHGAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LL+ G A D N T LH+A + + L+ GA K+G TPLH A R
Sbjct: 649 ELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALR 708
Query: 535 KNQM 546
+ +
Sbjct: 709 HHTL 712
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/227 (29%), Positives = 106/227 (46%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-AD 186
G T + A++ H DI+++LL+ VEA+ ++ +H A+ G+ + +L G AD
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGDEGAVIEVLHRGSAD 522
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ A PLHIA + + V L++ + +G T LH A + +L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK---NGHTPLHIAARK 537
L GA NG LH AA + LL K V + +G+T LH+AA
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALN 642
Query: 538 NQMETAATLLEYG-ALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N +E A L+ G A + ++ T LHLA ++ HT++ LL+ G
Sbjct: 643 NHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAG 689
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/174 (34%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +1
Query: 163 LLLQHGADVRAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKY 339
LL + DV A H AA Q+ H D+ L++ N + A K G A+H AA +
Sbjct: 450 LLKRPDVDVNGQCAGH--TAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-F 506
Query: 340 GNLKVANLLLAHGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
G+ +L G+A A K TPLHIA V TLL+ G G TP
Sbjct: 507 GDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTP 566
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
LH A K + + A LLE GA + GF LH AA +G+ +LL P
Sbjct: 567 LHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLP 620
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 12/195 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
G +H AA + +R+LL V+ K + T LH+A+ +V++A LL+ G
Sbjct: 596 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 655
Query: 181 -ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A++ + LH+A ++ + + L+ A L K G T LH A ++ L
Sbjct: 656 NANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQL 715
Query: 358 NLL--LAHGAAPDQAGKNGMTPLHI------AAQYDQQAVATTLLEKGADAKAVAKNGHT 513
L + D A + L + A + ++A L GAD K G +
Sbjct: 716 RQLQDMQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQS 775
Query: 514 PLHIAARKNQMETAA 558
PL + N + A
Sbjct: 776 PLDLCPDPNLCKALA 790
Score = 45.2 bits (102), Expect = 2e-04
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V +T +HLA HT I+R+L+R GA ++ + ++ TPLH A R + + LQ
Sbjct: 664 VNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLS-QLRQLQDMQ 722
Query: 184 DVRAITA---DHYNPLHI------AAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
DV + A N L + A K+ +A L + A L+ KKG + L L
Sbjct: 723 DVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 779
>AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein.
Length = 997
Score = 116 bits (278), Expect = 1e-25
Identities = 74/216 (34%), Positives = 106/216 (49%), Gaps = 4/216 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+ VH AA + +I +L R A + A+ + RQTPLHIA G++ + LL G
Sbjct: 488 GDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 547
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ PLH A + D+ A L+E A +T T GF ALH AA GN +LL
Sbjct: 548 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL 607
Query: 370 AHGAAP---DQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAARK 537
+ P D+ +G T LH+AA + VA L+ +G A+ N T LH+A +
Sbjct: 608 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 667
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
+ L+ GA + + K G TPLH A + HT
Sbjct: 668 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRH-HT 702
Score = 99.5 bits (237), Expect = 1e-20
Identities = 73/224 (32%), Positives = 98/224 (43%), Gaps = 3/224 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E V AA + + +L R V + T + AS+ G+VDI LLL+ DV
Sbjct: 424 EELVKAAANGDVAKVEDLLKRPDVDVNGQCAGH-TAMQAASQNGHVDILKLLLKQNVDVE 482
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A D +H AA V L +A L A K+ T LH+A G+L+V LL
Sbjct: 483 AEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLD 542
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK---NQ 543
G P G TPLH A + + LLE GAD NG LH AA + +
Sbjct: 543 FGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA 602
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
M + L + + + G+T LHLAA H E+ LL+ G
Sbjct: 603 MRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 646
Score = 98.3 bits (234), Expect = 3e-20
Identities = 64/184 (34%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +TP+H+A H +++ LL G + E TPLH A DI +LL+ GAD
Sbjct: 520 RRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 579
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKK--GFTALHLAAKYGNLKVA 357
V + +N LH AA + N L+ P KK G+TALHLAA +++VA
Sbjct: 580 VTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVA 639
Query: 358 NLLLAHGAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LL+ G A D N T LH+A + + L+ GA K+G TPLH A R
Sbjct: 640 ELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALR 699
Query: 535 KNQM 546
+ +
Sbjct: 700 HHTL 703
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/227 (29%), Positives = 106/227 (46%), Gaps = 5/227 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-AD 186
G T + A++ H DI+++LL+ VEA+ ++ +H A+ G+ + +L G AD
Sbjct: 455 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-FGDEGAVIEVLHRGSAD 513
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ A PLHIA + + V L++ + +G T LH A + +L
Sbjct: 514 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 573
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK---NGHTPLHIAARK 537
L GA NG LH AA + LL K V + +G+T LH+AA
Sbjct: 574 LEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALN 633
Query: 538 NQMETAATLLEYG-ALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N +E A L+ G A + ++ T LHLA ++ HT++ LL+ G
Sbjct: 634 NHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAG 680
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/174 (34%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +1
Query: 163 LLLQHGADVRAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKY 339
LL + DV A H AA Q+ H D+ L++ N + A K G A+H AA +
Sbjct: 441 LLKRPDVDVNGQCAGH--TAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAA-F 497
Query: 340 GNLKVANLLLAHGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
G+ +L G+A A K TPLHIA V TLL+ G G TP
Sbjct: 498 GDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTP 557
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
LH A K + + A LLE GA + GF LH AA +G+ +LL P
Sbjct: 558 LHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLP 611
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 12/195 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
G +H AA + +R+LL V+ K + T LH+A+ +V++A LL+ G
Sbjct: 587 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQG 646
Query: 181 -ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A++ + LH+A ++ + + L+ A L K G T LH A ++ L
Sbjct: 647 NANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQL 706
Query: 358 NLL--LAHGAAPDQAGKNGMTPLHI------AAQYDQQAVATTLLEKGADAKAVAKNGHT 513
L + D A + L + A + ++A L GAD K G +
Sbjct: 707 RQLQDMQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQS 766
Query: 514 PLHIAARKNQMETAA 558
PL + N + A
Sbjct: 767 PLDLCPDPNLCKALA 781
Score = 45.2 bits (102), Expect = 2e-04
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V +T +HLA HT I+R+L+R GA ++ + ++ TPLH A R + + LQ
Sbjct: 655 VNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLS-QLRQLQDMQ 713
Query: 184 DVRAITA---DHYNPLHI------AAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
DV + A N L + A K+ +A L + A L+ KKG + L L
Sbjct: 714 DVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 770
>BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 29
protein.
Length = 301
Score = 114 bits (275), Expect = 3e-25
Identities = 80/223 (35%), Positives = 109/223 (48%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +AA A H D +R L+ GA + + T L A++ G+ D+ L GA
Sbjct: 46 GTTLLMVAAYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGAST 105
Query: 190 RAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T D L +AA Q+ H V L++H A + G TAL LAA+ G L V LL
Sbjct: 106 EFRTKDEGTAL-LAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLL 164
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
LA GA +Q ++G PL IA+Q V +L +GAD A +G T L AA K
Sbjct: 165 LASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYN 224
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL++ T K G + LH A G+ + ALLLE G
Sbjct: 225 DVIKELLKFSP-TLGILKNGTSALHAAVLSGNIKTVALLLEAG 266
Score = 101 bits (242), Expect = 3e-21
Identities = 65/209 (31%), Positives = 101/209 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + AA+ H D++R L GA+ E + ++ T L AS+ G++ + LL+HGA++
Sbjct: 79 GTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDEGTALLAASQYGHMQVVETLLKHGANI 138
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D L +AA+ DV L+ A + + G L +A++ G+ +V ++L
Sbjct: 139 HDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVML 198
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA D A +G T L AA V LL K + + KNG + LH A ++
Sbjct: 199 LRGADRDAARNDGTTALLKAANKGYNDVIKELL-KFSPTLGILKNGTSALHAAVLSGNIK 257
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQ 636
T A LLE GA + +KA P L +
Sbjct: 258 TVALLLEAGADPSLRNKANELPAELTKNE 286
Score = 95.5 bits (227), Expect = 2e-19
Identities = 68/217 (31%), Positives = 103/217 (47%), Gaps = 1/217 (0%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAA-VEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR + ++++LL +G V+ + T L +A+ G++D L+ GAD+
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRES 78
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
L AA+Q ++DV L A TK TAL A++YG+++V LL HGA
Sbjct: 79 GTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDEGTALLAASQYGHMQVVETLLKHGANI 138
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+G T L +AAQ V LL GA ++G PL IA++ E +L
Sbjct: 139 HDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVML 198
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
GA +A G T L AA +G+ ++ LL+ P
Sbjct: 199 LRGADRDAARNDGTTALLKAANKGYNDVIKELLKFSP 235
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Frame = +1
Query: 427 AAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKA 603
AA+ A+ LL G D +G T L +AA ++ L+ GA N + ++
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRES 78
Query: 604 GFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
G T L AAQQGH ++ L G T+F
Sbjct: 79 GTTALFFAAQQGHNDVVRFLFGFGASTEF 107
>AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 518
Score = 114 bits (275), Expect = 3e-25
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 14 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 133
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ D + LL KGA+ + G TPL +AA+ ++E
Sbjct: 134 HGANVNGSHSMCGWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 193
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 194 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Score = 113 bits (271), Expect = 8e-25
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 42 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 101
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 102 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQDNAEI 161
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 162 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 221
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 222 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 107 bits (258), Expect = 3e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 255
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 256 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 303
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 282 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 310
>AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens
cDNA FLJ20636 fis, clone KAT03434. ).
Length = 262
Score = 113 bits (273), Expect = 5e-25
Identities = 71/219 (32%), Positives = 109/219 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA H +R L+ G AV + +PLH A G++ +LL+HGA V
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+TAD + PL A + D L++H A + + + +H AA+ G+++ N L+A+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLIAY 156
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G D + TPL++A + Q+A LLE GAD K +PLH AR E A
Sbjct: 157 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ-GKGQDSPLHAVARTASEELA 215
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L+++GA T A++ G P+ L + L EG
Sbjct: 216 CLLMDFGADTQAKNAEGKRPVELVPPESPLAQLFLEREG 254
Score = 86.2 bits (204), Expect = 1e-16
Identities = 60/191 (31%), Positives = 88/191 (46%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
+P+H A+ G+ L+ G V ITADH +PLH A + L++H A +
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T T L A G+ NLLL HGA+ Q + +P+H AA+ +L+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAY 156
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
G + + TPL++A Q LLE GA N + K +PLH A+ E+
Sbjct: 157 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASEELA 215
Query: 655 ALLLEGGPGTQ 687
LL++ G TQ
Sbjct: 216 CLLMDFGADTQ 226
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Frame = +1
Query: 211 YNPLHIAAKQHNHDVAAA-LIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
++P+H AA H H ++ LI + T + LH A G+L +LL HGA
Sbjct: 37 WSPMHEAAI-HGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQV 95
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+ + TPL A LL+ GA + + +P+H AAR+ +E +L+
Sbjct: 96 NGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLI 154
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
YG + + TPL+LA + LLE G
Sbjct: 155 AYGGNIDHKISHLGTPLYLACENQQRACVKKLLESG 190
Score = 58.4 bits (135), Expect = 2e-08
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Frame = +1
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
PL ++ +H AA +G+ L++ G A + + ++PLH A +
Sbjct: 28 PLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKI 87
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ GA V + HTPL A + LL++GA ES +P+H AA++GH
Sbjct: 88 LLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGH 146
Query: 643 TE-MCALLLEGG 675
E + +L+ GG
Sbjct: 147 VECVNSLIAYGG 158
>AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens
cDNA FLJ43370 fis, clone NTONG2005277, weakly similar
to ANKYRIN 1. ).
Length = 588
Score = 113 bits (272), Expect = 6e-25
Identities = 73/214 (34%), Positives = 106/214 (49%), Gaps = 2/214 (0%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAV--EAKARERQTPLHIASRLGNVDIAVLLLQHG 180
+G P+H A I+ I+L E K + +TPL +A + G V+ LL+ G
Sbjct: 75 KGWFPLHEAVVQPIQQILEIVLDASYKTLWEFKTCDGETPLTLAVKAGLVENVRTLLEKG 134
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
PL IA K+ ++D+ + LI+HN L K ++A+H AAK G +
Sbjct: 135 VWPNTKNDKGETPLLIAVKKGSYDMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVA 194
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LLL HG G+TPL +AA+Y V L+ KG D A+A +G + L AA
Sbjct: 195 LLLKHGGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGG 254
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
+ + LLEYG N ++AG P+H AA +GH
Sbjct: 255 NPDCISLLLEYGGSGNVPNRAGHLPIHRAAYEGH 288
Score = 106 bits (255), Expect = 7e-23
Identities = 69/225 (30%), Positives = 105/225 (46%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T GETP+ LA +A + +R LL G K + +TPL IA + G+ D+ L++H
Sbjct: 108 TCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAVKKGSYDMVSTLIKHN 167
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ ++ +H AAKQ D+ A L++H + G T L +AA+YG+ V
Sbjct: 168 TSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYGHCDVLE 227
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ G +G + L AA + LLE G + GH P+H AA +
Sbjct: 228 HLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNRAGHLPIHRAAYEG 287
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ + NA K+G TP+H AA + + LL+E G
Sbjct: 288 HYLALKYLIPVTS-KNAIRKSGLTPIHSAADGQNAQCLELLIENG 331
Score = 76.6 bits (180), Expect = 9e-14
Identities = 62/233 (26%), Positives = 100/233 (42%), Gaps = 9/233 (3%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ + +H AA+ DI+ +LL++G V + TPL +A+ G+ D+ L+ G
Sbjct: 175 VKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGG 234
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
DV A+ D + L AA N D + L+E+ + G +H AA G+
Sbjct: 235 DVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNRAGHLPIHRAAYEGHYLALKY 294
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKN---------GHTP 516
L+ + + K+G+TP+H AA L+E G D + + T
Sbjct: 295 LIPV-TSKNAIRKSGLTPIHSAADGQNAQCLELLIENGFDVNTLLADHISQSCDDERKTA 353
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ A N + LL GA N + L +A + + E+ LLL G
Sbjct: 354 LYFAVSNNDVHCTEVLLAAGADPNLDP---LNCLLVAVRANNYEIVRLLLSHG 403
Score = 54.8 bits (126), Expect = 3e-07
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 271 EHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQA 450
E PL+A +K L A K G++ + + A D+A + G PLH A Q
Sbjct: 35 ERFVPLSAQNRK----LVEAIKQGHILELQEYVKYKYAMDEADEKGWFPLHEAVVQPIQQ 90
Query: 451 VATTLLEKGADAKAVAK--NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHL 624
+ +L+ K +G TPL +A + +E TLLE G N ++ G TPL +
Sbjct: 91 ILEIVLDASYKTLWEFKTCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLI 150
Query: 625 AAQQGHTEMCALLLE 669
A ++G +M + L++
Sbjct: 151 AVKKGSYDMVSTLIK 165
Score = 40.7 bits (91), Expect = 0.005
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 9/133 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA H ++ L+ + A + TP+H A+ N LL+++G DV
Sbjct: 276 GHLPIHRAAYEGHYLALKYLIPV-TSKNAIRKSGLTPIHSAADGQNAQCLELLIENGFDV 334
Query: 190 RAITADHYN---------PLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG 342
+ ADH + L+ A ++ L+ A L +A +
Sbjct: 335 NTLLADHISQSCDDERKTALYFAVSNNDVHCTEVLLAAGAD---PNLDPLNCLLVAVRAN 391
Query: 343 NLKVANLLLAHGA 381
N ++ LLL+HGA
Sbjct: 392 NYEIVRLLLSHGA 404
>AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containing
protein ASB-2 protein.
Length = 544
Score = 113 bits (272), Expect = 6e-25
Identities = 69/222 (31%), Positives = 112/222 (50%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T++ ET V+LA H D + LL+ GA + + R+TPL+ A N + +L+QH
Sbjct: 80 TLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHN 139
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD + LH + +++ +V L+ A + + G T L +AA+ G L+
Sbjct: 140 ADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG-TPLFVAAQSGQLEALR 198
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L +GA + + + L+ A + + + V LL +GADA K+G PLHIA++K
Sbjct: 199 FLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKG 258
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL + T ++G +PLHLAA++ H E+ LL
Sbjct: 259 NYRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEVLEALL 299
Score = 108 bits (259), Expect = 2e-23
Identities = 64/220 (29%), Positives = 110/220 (50%), Gaps = 1/220 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G P+H AA +++L R ++ + + +T +++A+ G++D + LLQ GA+
Sbjct: 49 GWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAE 108
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
PL+ A ++ N + L++HNA +G+TALH + +L+V +L
Sbjct: 109 PDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQIL 168
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
++ GA + G TPL +AAQ Q L + GAD A + + L+ A +
Sbjct: 169 VSGGAKVESKNAYG-TPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHE 227
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
E LL GA N +K G PLH+A+++G+ + +LL
Sbjct: 228 EVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 267
Score = 98.3 bits (234), Expect = 3e-20
Identities = 66/232 (28%), Positives = 114/232 (49%), Gaps = 9/232 (3%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG T +H + N ++++IL+ GA VE+K TPL +A++ G ++ L ++GAD
Sbjct: 148 RGWTALHESVSRNDLEVMQILVSGGAKVESK-NAYGTPLFVAAQSGQLEALRFLAKYGAD 206
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ +D+ + L+ A K + +V L+ A T K G LH+A+K GN ++ +L
Sbjct: 207 INTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQML 266
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD---------AKAVAKNGHTPL 519
L + + ++G++PLH+AA+ + V LL D A+ + L
Sbjct: 267 LP-VTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSAL 325
Query: 520 HIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A N + LL++GA N + +PL +A + G LLL+ G
Sbjct: 326 YFAVVNNNVYATELLLQHGADPNRDV---ISPLLVAIRHGCLRTMQLLLDHG 374
Score = 70.9 bits (166), Expect = 4e-12
Identities = 55/201 (27%), Positives = 97/201 (48%), Gaps = 9/201 (4%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+ +AA++ + +R L + GA + +A + + L+ A + + ++ LL GAD
Sbjct: 183 TPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANK 242
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
D PLHIA+K+ N+ + L+ + T + G + LHLAA+ + +V LL+
Sbjct: 243 TNKDGLLPLHIASKKGNYRIVQMLLPVTSR-TRIRRSGVSPLHLAAERNHDEVLEALLSA 301
Query: 376 G------AAPDQAG---KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
AP++A + L+ A + LL+ GAD ++ +PL +A
Sbjct: 302 RFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVA 358
Query: 529 ARKNQMETAATLLEYGALTNA 591
R + T LL++GA +A
Sbjct: 359 IRHGCLRTMQLLLDHGANIDA 379
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL-AHGAAPD 390
+PL A K + + +I+ L K+G+ LH AA YG + +L A+ D
Sbjct: 18 DPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 77
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
Q T +++A +LL+ GA+ K+ TPL+ A + E L++
Sbjct: 78 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 137
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ A TN G+T LH + + E+ +L+ GG
Sbjct: 138 HNADTNHRCNRGWTALHESVSRNDLEVMQILVSGG 172
Score = 37.9 bits (84), Expect = 0.038
Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H+A++ + I+++LL + + R +PLH+A+ + ++ LL DV
Sbjct: 247 GLLPLHIASKKGNYRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEVLEALLSARFDV 305
Query: 190 RAITADHY---------NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYG 342
A + L+ A +N L++H A + + L +A ++G
Sbjct: 306 NTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGAD---PNRDVISPLLVAIRHG 362
Query: 343 NLKVANLLLAHGAAPD 390
L+ LLL HGA D
Sbjct: 363 CLRTMQLLLDHGANID 378
Score = 32.3 bits (70), Expect = 1.9
Identities = 22/68 (32%), Positives = 35/68 (51%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R + ++ A N+ +LL++GA R+ +PL +A R G + LLL HGA+
Sbjct: 320 RRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGAN 376
Query: 187 VRAITADH 210
+ A A H
Sbjct: 377 IDAYIATH 384
Score = 31.1 bits (67), Expect = 4.3
Identities = 18/57 (31%), Positives = 25/57 (43%)
Frame = +1
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
PL A + E T+++ G +K G+ PLH AA G +L PGT
Sbjct: 19 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT 75
>BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein.
Length = 553
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 49 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 108
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 109 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 168
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 169 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 228
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 229 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 270
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 77 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 136
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 137 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 196
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 197 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 256
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 257 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 302
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 111 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 170
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 171 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 230
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 231 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 290
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 291 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 338
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 317 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 345
>BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 14 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 133
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 134 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 193
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 194 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 42 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 101
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 102 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 161
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 162 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 221
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 222 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 255
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 256 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 303
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 282 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 310
>BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 14 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 133
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 134 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 193
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 194 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 42 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 101
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 102 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 161
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 162 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 221
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 222 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 255
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 256 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 303
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 282 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 310
>AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ10123 fis, clone HEMBA1002939, weakly similar to
ANKYRIN R. ).
Length = 518
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 14 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 133
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 134 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 193
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 194 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 42 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 101
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 102 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 161
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 162 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 221
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 222 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 255
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 256 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 303
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 282 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 310
>AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein.
Length = 518
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 14 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 133
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 134 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 193
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 194 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 42 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 101
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 102 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 161
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 162 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 221
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 222 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 255
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 256 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 303
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 282 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 310
>AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 14 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 73
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 74 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 133
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 134 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 193
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 194 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 235
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 42 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 101
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 102 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 161
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 162 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 221
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 222 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 76 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 196 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 255
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 256 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 303
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 282 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 310
>AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 340
Score = 113 bits (271), Expect = 8e-25
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 24 VGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 83
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 84 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 143
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 144 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 203
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 204 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 245
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 52 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 111
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 112 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 171
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 172 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 231
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 232 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 277
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 86 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 145
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 146 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 205
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 206 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 265
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 266 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 313
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 292 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 320
>AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 512
Score = 112 bits (270), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 6/226 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
RG P+H AA N + +++L+ ++ ++ K E LH+A+ G+ I +LL+
Sbjct: 36 RGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEA 95
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK-GFTALHLAAKYGNLKV 354
GAD A T + PL +A + DV L++H A + + G+ +LH A+ N ++
Sbjct: 96 GADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEI 155
Query: 355 ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL GA + G+TPL +AAQY + + L+ GA+ A + TPL IAA+
Sbjct: 156 IKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQ 215
Query: 535 KNQMETAATLLEYGALTN--AESKAGFTPLHLAAQQGHTEMCALLL 666
+ + LL GA + + P+H AAQ GHT++ LL+
Sbjct: 216 EGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 261
Score = 112 bits (269), Expect = 1e-24
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD---VR 192
V LAAR + ++R LL+ G +V+ P+H A+ +V+ +L+ + ++
Sbjct: 8 VGLAAREANVKVLRQLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIK 67
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
T + + LH+AA Q + + L+E A ATT + T L LA + G + V LLL
Sbjct: 68 MKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQ 127
Query: 373 HGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
HGA + + G LH A+ + + LL KGA+ + G TPL +AA+ ++E
Sbjct: 128 HGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLE 187
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + L+ GA N ++ TPL +AAQ+GHT+ LLL G
Sbjct: 188 SLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSG 229
Score = 108 bits (259), Expect = 2e-23
Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL +A G +D+ LLLQHG
Sbjct: 70 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 129
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 130 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 189
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 190 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 249
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 250 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 297
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 276 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 304
>BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein.
Length = 467
Score = 111 bits (267), Expect = 3e-24
Identities = 76/220 (34%), Positives = 106/220 (48%), Gaps = 14/220 (6%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA HT+++R+LLR A ++ R T LH A G+ +LL GAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSAPGGR-TALHEACAAGHTACVHVLLVAGADPNI 176
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANLLLA 372
D PLH+ + A L+ A + +++ T LH+AA+ G++++A+LLL
Sbjct: 177 ADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 236
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAV----ATT---------LLEKGADAKAVAKNGHT 513
GA PD G TPL A Q++ ATT LL GADA A ++
Sbjct: 237 RGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQR 296
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
PLH+A R+ LL G N G TPLH A Q
Sbjct: 297 PLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQ 336
Score = 84.6 bits (200), Expect = 3e-16
Identities = 60/187 (32%), Positives = 89/187 (47%), Gaps = 14/187 (7%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H A A HT + +LL GA ++ + PLH+ G ++ A LLL+ GA V
Sbjct: 148 GRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGARV 207
Query: 190 RAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKY--------- 339
+ + PLH+AA+ + ++A L+ A A +G+T L A
Sbjct: 208 DGRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAACDVRCQSITDAE 267
Query: 340 ----GNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
L++ +LLL+ GA D A ++ PLH+A + AV LL G A + G
Sbjct: 268 ATTARCLQLCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGG 327
Query: 508 HTPLHIA 528
HTPLH A
Sbjct: 328 HTPLHCA 334
Score = 80.6 bits (190), Expect = 5e-15
Identities = 49/122 (40%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T LH+AA G+ +V LLL A PD A G T LH A A LL GAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSA-PGGRTALHEACAAGHTACVHVLLVAGADPNI 176
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
++G PLH+ +E A LL +GA + S+ TPLH+AA+ GH E+ LLL
Sbjct: 177 ADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 236
Query: 670 GG 675
G
Sbjct: 237 RG 238
Score = 76.6 bits (180), Expect = 9e-14
Identities = 54/163 (33%), Positives = 79/163 (48%), Gaps = 14/163 (8%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G+ P+HL + +LLR GA V+ ++ E + TPLH+A+RLG+V++A LLL+ GA
Sbjct: 181 GKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLRRGAC 240
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAA-------------LIEHNAPLTATTKKGFTALHL 327
A A+ + PL A + A L+ A A + LHL
Sbjct: 241 PDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQRPLHL 300
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
A + G+ V LLL+ G + + G TPLH A Q A+A
Sbjct: 301 ACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALA 343
Score = 70.9 bits (166), Expect = 4e-12
Identities = 62/204 (30%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +1
Query: 106 ERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP 285
E TPLH+A+ G+ ++ LLL+ A + LH A + L+ A
Sbjct: 115 ELTTPLHVAASRGHTEVLRLLLRRRARPDSAPGGR-TALHEACAAGHTACVHVLLVAGAD 173
Query: 286 LTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATT 462
+ G LHL G L+ A LLL GA D ++ + TPLH+AA+ +A
Sbjct: 174 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 233
Query: 463 LLEKGADAKAVAKNGHTPLHI-------------AARKNQMETAATLLEYGALTNAESKA 603
LL +GA A G TPL A ++ + LL GA +A +
Sbjct: 234 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 293
Query: 604 GFTPLHLAAQQGHTEMCALLLEGG 675
PLHLA ++GH + LLL G
Sbjct: 294 KQRPLHLACRRGHAAVVELLLSCG 317
>AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens
cDNA FLJ43577 fis, clone SKMUS2006394, weakly similar
to Mus musculus ankyrin repeat-containing protein Asb-4
mRNA. ).
Length = 452
Score = 111 bits (267), Expect = 3e-24
Identities = 76/220 (34%), Positives = 106/220 (48%), Gaps = 14/220 (6%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA HT+++R+LLR A ++ R T LH A G+ +LL GAD
Sbjct: 103 TPLHVAASRGHTEVLRLLLRRRARPDSAPGGR-TALHEACAAGHTACVHVLLVAGADPNI 161
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANLLLA 372
D PLH+ + A L+ A + +++ T LH+AA+ G++++A+LLL
Sbjct: 162 ADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 221
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAV----ATT---------LLEKGADAKAVAKNGHT 513
GA PD G TPL A Q++ ATT LL GADA A ++
Sbjct: 222 RGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQR 281
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
PLH+A R+ LL G N G TPLH A Q
Sbjct: 282 PLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQ 321
Score = 84.6 bits (200), Expect = 3e-16
Identities = 60/187 (32%), Positives = 89/187 (47%), Gaps = 14/187 (7%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H A A HT + +LL GA ++ + PLH+ G ++ A LLL+ GA V
Sbjct: 133 GRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGARV 192
Query: 190 RAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKY--------- 339
+ + PLH+AA+ + ++A L+ A A +G+T L A
Sbjct: 193 DGRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAACDVRCQSITDAE 252
Query: 340 ----GNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
L++ +LLL+ GA D A ++ PLH+A + AV LL G A + G
Sbjct: 253 ATTARCLQLCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGG 312
Query: 508 HTPLHIA 528
HTPLH A
Sbjct: 313 HTPLHCA 319
Score = 80.6 bits (190), Expect = 5e-15
Identities = 49/122 (40%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T LH+AA G+ +V LLL A PD A G T LH A A LL GAD
Sbjct: 103 TPLHVAASRGHTEVLRLLLRRRARPDSA-PGGRTALHEACAAGHTACVHVLLVAGADPNI 161
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
++G PLH+ +E A LL +GA + S+ TPLH+AA+ GH E+ LLL
Sbjct: 162 ADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 221
Query: 670 GG 675
G
Sbjct: 222 RG 223
Score = 76.6 bits (180), Expect = 9e-14
Identities = 54/163 (33%), Positives = 79/163 (48%), Gaps = 14/163 (8%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G+ P+HL + +LLR GA V+ ++ E + TPLH+A+RLG+V++A LLL+ GA
Sbjct: 166 GKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLRRGAC 225
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAA-------------LIEHNAPLTATTKKGFTALHL 327
A A+ + PL A + A L+ A A + LHL
Sbjct: 226 PDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQRPLHL 285
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
A + G+ V LLL+ G + + G TPLH A Q A+A
Sbjct: 286 ACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALA 328
Score = 70.9 bits (166), Expect = 4e-12
Identities = 62/204 (30%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +1
Query: 106 ERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP 285
E TPLH+A+ G+ ++ LLL+ A + LH A + L+ A
Sbjct: 100 ELTTPLHVAASRGHTEVLRLLLRRRARPDSAPGGR-TALHEACAAGHTACVHVLLVAGAD 158
Query: 286 LTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATT 462
+ G LHL G L+ A LLL GA D ++ + TPLH+AA+ +A
Sbjct: 159 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 218
Query: 463 LLEKGADAKAVAKNGHTPLHI-------------AARKNQMETAATLLEYGALTNAESKA 603
LL +GA A G TPL A ++ + LL GA +A +
Sbjct: 219 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 278
Query: 604 GFTPLHLAAQQGHTEMCALLLEGG 675
PLHLA ++GH + LLL G
Sbjct: 279 KQRPLHLACRRGHAAVVELLLSCG 302
>AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein.
Length = 429
Score = 111 bits (267), Expect = 3e-24
Identities = 76/220 (34%), Positives = 106/220 (48%), Gaps = 14/220 (6%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H+AA HT+++R+LLR A ++ R T LH A G+ +LL GAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSAPGGR-TALHEACAAGHTACVHVLLVAGADPNI 176
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANLLLA 372
D PLH+ + A L+ A + +++ T LH+AA+ G++++A+LLL
Sbjct: 177 ADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 236
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAV----ATT---------LLEKGADAKAVAKNGHT 513
GA PD G TPL A Q++ ATT LL GADA A ++
Sbjct: 237 RGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQR 296
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
PLH+A R+ LL G N G TPLH A Q
Sbjct: 297 PLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQ 336
Score = 84.6 bits (200), Expect = 3e-16
Identities = 60/187 (32%), Positives = 89/187 (47%), Gaps = 14/187 (7%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H A A HT + +LL GA ++ + PLH+ G ++ A LLL+ GA V
Sbjct: 148 GRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGARV 207
Query: 190 RAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKY--------- 339
+ + PLH+AA+ + ++A L+ A A +G+T L A
Sbjct: 208 DGRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAACDVRCQSITDAE 267
Query: 340 ----GNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
L++ +LLL+ GA D A ++ PLH+A + AV LL G A + G
Sbjct: 268 ATTARCLQLCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGG 327
Query: 508 HTPLHIA 528
HTPLH A
Sbjct: 328 HTPLHCA 334
Score = 80.6 bits (190), Expect = 5e-15
Identities = 49/122 (40%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
T LH+AA G+ +V LLL A PD A G T LH A A LL GAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSA-PGGRTALHEACAAGHTACVHVLLVAGADPNI 176
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
++G PLH+ +E A LL +GA + S+ TPLH+AA+ GH E+ LLL
Sbjct: 177 ADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 236
Query: 670 GG 675
G
Sbjct: 237 RG 238
Score = 76.6 bits (180), Expect = 9e-14
Identities = 54/163 (33%), Positives = 79/163 (48%), Gaps = 14/163 (8%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G+ P+HL + +LLR GA V+ ++ E + TPLH+A+RLG+V++A LLL+ GA
Sbjct: 181 GKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLRRGAC 240
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAA-------------LIEHNAPLTATTKKGFTALHL 327
A A+ + PL A + A L+ A A + LHL
Sbjct: 241 PDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQRPLHL 300
Query: 328 AAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
A + G+ V LLL+ G + + G TPLH A Q A+A
Sbjct: 301 ACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALA 343
Score = 70.9 bits (166), Expect = 4e-12
Identities = 62/204 (30%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +1
Query: 106 ERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP 285
E TPLH+A+ G+ ++ LLL+ A + LH A + L+ A
Sbjct: 115 ELTTPLHVAASRGHTEVLRLLLRRRARPDSAPGGR-TALHEACAAGHTACVHVLLVAGAD 173
Query: 286 LTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATT 462
+ G LHL G L+ A LLL GA D ++ + TPLH+AA+ +A
Sbjct: 174 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 233
Query: 463 LLEKGADAKAVAKNGHTPLHI-------------AARKNQMETAATLLEYGALTNAESKA 603
LL +GA A G TPL A ++ + LL GA +A +
Sbjct: 234 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 293
Query: 604 GFTPLHLAAQQGHTEMCALLLEGG 675
PLHLA ++GH + LLL G
Sbjct: 294 KQRPLHLACRRGHAAVVELLLSCG 317
>D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein.
Length = 226
Score = 111 bits (266), Expect = 3e-24
Identities = 63/171 (36%), Positives = 90/171 (52%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H A A HT+I+ LL+ G V K +PLHIA+ G +I LL GA V A
Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ + PLH AA ++ H++A L+E A A TA+H AA GNLK+ ++LL +
Sbjct: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
A+ + G TPLH+A ++ A L+ +GA K TPL +A
Sbjct: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 93.1 bits (221), Expect = 9e-19
Identities = 53/157 (33%), Positives = 76/157 (48%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
D LH A + ++ L++ P+ G++ LH+AA G ++ LL GA
Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
+ +NG TPLH AA ++ +A LLE GA+ A T +H AA K ++ L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L Y A TN + G TPLHLA + E LL+ G
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
Score = 91.9 bits (218), Expect = 2e-18
Identities = 58/175 (33%), Positives = 83/175 (47%)
Frame = +1
Query: 103 RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNA 282
++ +T LH A G+ +I LLQ G V ++PLHIAA ++ AL+ A
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
+ A + G T LH AA ++A +LL GA PD T +H AA +
Sbjct: 98 QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
LL A G+TPLH+A + ++E A L+ GA E+K TPL +A
Sbjct: 158 LLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 90.2 bits (214), Expect = 7e-18
Identities = 51/139 (36%), Positives = 74/139 (53%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ +++ + T T + TALH A G+ ++ LL G + G +PLHIA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
A + + LL KGA AV +NG TPLH AA KN+ E A LLE GA +A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 610 TPLHLAAQQGHTEMCALLL 666
T +H AA +G+ +M +LL
Sbjct: 141 TAMHRAAAKGNLKMIHILL 159
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +P+H+AA A +I++ LL GA V A + TPLH A+ +IAV+LL+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 190 RAITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A DHY +H AA + N + L+ + A +G T LHLA ++ A L
Sbjct: 133 DA--KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 364 LLAHGAAPDQAGKNGMTPLHIA 429
L++ GA+ K TPL +A
Sbjct: 191 LVSQGASIYIENKEEKTPLQVA 212
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/104 (34%), Positives = 50/104 (48%)
Frame = +1
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
+LA + + ++ T LH A + LL+ G G +PLHIAA +
Sbjct: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGR 85
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL GA NA ++ G TPLH AA + E+ +LLEGG
Sbjct: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
>BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 111 bits (266), Expect = 3e-24
Identities = 63/171 (36%), Positives = 90/171 (52%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H A A HT+I+ LL+ G V K +PLHIA+ G +I LL GA V A
Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ + PLH AA ++ H++A L+E A A TA+H AA GNLK+ ++LL +
Sbjct: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
A+ + G TPLH+A ++ A L+ +GA K TPL +A
Sbjct: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 93.1 bits (221), Expect = 9e-19
Identities = 53/157 (33%), Positives = 76/157 (48%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
D LH A + ++ L++ P+ G++ LH+AA G ++ LL GA
Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
+ +NG TPLH AA ++ +A LLE GA+ A T +H AA K ++ L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L Y A TN + G TPLHLA + E LL+ G
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
Score = 91.9 bits (218), Expect = 2e-18
Identities = 58/175 (33%), Positives = 83/175 (47%)
Frame = +1
Query: 103 RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNA 282
++ +T LH A G+ +I LLQ G V ++PLHIAA ++ AL+ A
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
+ A + G T LH AA ++A +LL GA PD T +H AA +
Sbjct: 98 QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
LL A G+TPLH+A + ++E A L+ GA E+K TPL +A
Sbjct: 158 LLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 90.2 bits (214), Expect = 7e-18
Identities = 51/139 (36%), Positives = 74/139 (53%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ +++ + T T + TALH A G+ ++ LL G + G +PLHIA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
A + + LL KGA AV +NG TPLH AA KN+ E A LLE GA +A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 610 TPLHLAAQQGHTEMCALLL 666
T +H AA +G+ +M +LL
Sbjct: 141 TAMHRAAAKGNLKMIHILL 159
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +P+H+AA A +I++ LL GA V A + TPLH A+ +IAV+LL+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 190 RAITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A DHY +H AA + N + L+ + A +G T LHLA ++ A L
Sbjct: 133 DA--KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 364 LLAHGAAPDQAGKNGMTPLHIA 429
L++ GA+ K TPL +A
Sbjct: 191 LVSQGASIYIENKEEKTPLQVA 212
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/104 (34%), Positives = 50/104 (48%)
Frame = +1
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
+LA + + ++ T LH A + LL+ G G +PLHIAA +
Sbjct: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGR 85
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL GA NA ++ G TPLH AA + E+ +LLEGG
Sbjct: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
>BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein.
Length = 1500
Score = 111 bits (266), Expect = 3e-24
Identities = 80/229 (34%), Positives = 115/229 (50%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL NGA +EA++ R + TPL +A G ++ LLL GA
Sbjct: 1115 KGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGA 1174
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G+
Sbjct: 1175 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAV 1234
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 1235 KLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAAS 1294
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 1295 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRG 1343
Score = 109 bits (261), Expect = 1e-23
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 1151 DTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 1210
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 1211 SRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSL 1270
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 1271 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 1330
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LAA GH ++ LL++ G
Sbjct: 1331 GHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAG 1376
Score = 107 bits (256), Expect = 5e-23
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G +++A L++ GAD
Sbjct: 500 GYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD 559
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL AA++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 560 IELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 616
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ + A N HT L +A
Sbjct: 617 LQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGH 676
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L AA+ GHT + LL+
Sbjct: 677 LAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 718
Score = 106 bits (254), Expect = 9e-23
Identities = 69/225 (30%), Positives = 113/225 (50%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H ++++ LL GA++E + ++ TPL +A+ G+V + +LL +GAD+
Sbjct: 1084 DTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIE 1143
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 1144 AQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 1203
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA A LL+ G+D A + N +T L +A +
Sbjct: 1204 NAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQG 1263
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 1264 RTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1308
Score = 105 bits (252), Expect = 2e-22
Identities = 72/224 (32%), Positives = 116/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A + D++++LL +GA++E TPL A G+V++A LLL++GA +
Sbjct: 334 GNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGI 393
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + ++ L+E A T + TAL A G+++VA LL
Sbjct: 394 NTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 453
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA + V G+TPL AAR+
Sbjct: 454 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHE 513
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G E+ L++ G
Sbjct: 514 EMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAG 557
Score = 105 bits (251), Expect = 2e-22
Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H +++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 402 ESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 461
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLL
Sbjct: 462 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 521
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL AA++ +E
Sbjct: 522 QGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD---IELGCSTPLMEAAQEGHLE 578
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 579 LVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAG 620
Score = 98.7 bits (235), Expect = 2e-20
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ A A H ++ R+LL NGA + + E +++ L +A G++++ LL+ GAD
Sbjct: 367 GHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGAD 426
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 427 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 486
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA+ ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 487 IERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGF 546
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A L++ GA + E TPL AAQ+GH E+ LL G
Sbjct: 547 LEVADFLIKAGA--DIELGCS-TPLMEAAQEGHLELVKYLLAAG 587
Score = 94.7 bits (225), Expect = 3e-19
Identities = 75/223 (33%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA++E E TPL A+R G+ ++ LLL GA++
Sbjct: 468 ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 527
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L AA+ G+L++ LL
Sbjct: 528 AQTEETQETALTLACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLL 584
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 585 AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVC 644
Query: 550 TAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T L+ GA N + T L LA GH + LLL G
Sbjct: 645 TVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 687
Score = 94.3 bits (224), Expect = 4e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+ LLL G+D+
Sbjct: 1185 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1244
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 1245 NAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1304
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +AA
Sbjct: 1305 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANG 1363
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ L++ GA +A TPL A ++GH ++ L++
Sbjct: 1364 GHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1407
Score = 88.6 bits (210), Expect = 2e-17
Identities = 62/177 (35%), Positives = 92/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
A+L + D+ A T ++H L +A + ++ L+E A + KKGFT L LAA
Sbjct: 1065 AMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1124
Query: 334 KYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
G++ V +LL +GA + Q+ + TPL +A +Q V LL +GA+ + + +
Sbjct: 1125 TAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDY 1184
Query: 511 TPLHIAARKNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
TPL +AA + LL GA N+ SK G +PL LAA GHT LLL+ G
Sbjct: 1185 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG 1241
Score = 83.8 bits (198), Expect = 6e-16
Identities = 61/190 (32%), Positives = 87/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA HT +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 1218 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 1277
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 1278 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 1337
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +AA V L++ GAD A TPL A RK
Sbjct: 1338 LLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 1397
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 1398 HVKVVRYLVK 1407
Score = 82.2 bits (194), Expect = 2e-15
Identities = 63/180 (35%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 245 GDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITP 304
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G++K+ LLLAH A + G T L A V LLE GA +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHN 364
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL A +E A LLE GA N S + + L LA +GH EM LLE G
Sbjct: 365 ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAG 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 64/228 (28%), Positives = 98/228 (42%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 166 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAE 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A +D+ + ++ + V LIE + + T++G + L LA G ++A
Sbjct: 226 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRS-VNEHTEEGESLLCLACSAGYYELAQ 284
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL AA + LL AD A + G+T L A
Sbjct: 285 VLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAG 344
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LLE GA ++ G TPL A GH E+ LLLE G G
Sbjct: 345 GYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAG 392
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA ++ L++ GA +E TPL A++ G++++ LL GA+V
Sbjct: 535 ETALTLACCGGFLEVADFLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVH 591
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G++ L++
Sbjct: 592 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLIS 651
Query: 373 HGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ N T L +A AV LL GAD K+G T L AA+
Sbjct: 652 KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTS 711
Query: 550 TAATLLEY 573
LL+Y
Sbjct: 712 VVCYLLDY 719
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA T+++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 1254 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1313
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LAA G+L V LL+
Sbjct: 1314 PPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLV 1373
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 1374 QAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKE 1408
Score = 64.1 bits (149), Expect = 5e-10
Identities = 43/124 (34%), Positives = 63/124 (50%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G+V L+ G
Sbjct: 594 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 653
Query: 181 ADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V TA++ + L +A + V L+ H A T K G T L AAK G+ V
Sbjct: 654 ANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVV 713
Query: 358 NLLL 369
LL
Sbjct: 714 CYLL 717
Score = 46.0 bits (104), Expect = 1e-04
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A T L +A G++ + LLL HGAD
Sbjct: 630 GRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGAD 689
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
D L AAK + V L+++ L + T L
Sbjct: 690 PTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQL 734
Score = 46.0 bits (104), Expect = 1e-04
Identities = 21/56 (37%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LAA H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 1352 KGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1407
>AL031177-6|CAA20117.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 111 bits (266), Expect = 3e-24
Identities = 63/171 (36%), Positives = 90/171 (52%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H A A HT+I+ LL+ G V K +PLHIA+ G +I LL GA V A
Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ + PLH AA ++ H++A L+E A A TA+H AA GNLK+ ++LL +
Sbjct: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
A+ + G TPLH+A ++ A L+ +GA K TPL +A
Sbjct: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 93.1 bits (221), Expect = 9e-19
Identities = 53/157 (33%), Positives = 76/157 (48%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
D LH A + ++ L++ P+ G++ LH+AA G ++ LL GA
Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
+ +NG TPLH AA ++ +A LLE GA+ A T +H AA K ++ L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L Y A TN + G TPLHLA + E LL+ G
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
Score = 91.9 bits (218), Expect = 2e-18
Identities = 58/175 (33%), Positives = 83/175 (47%)
Frame = +1
Query: 103 RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNA 282
++ +T LH A G+ +I LLQ G V ++PLHIAA ++ AL+ A
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
+ A + G T LH AA ++A +LL GA PD T +H AA +
Sbjct: 98 QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
LL A G+TPLH+A + ++E A L+ GA E+K TPL +A
Sbjct: 158 LLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 90.2 bits (214), Expect = 7e-18
Identities = 51/139 (36%), Positives = 74/139 (53%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ +++ + T T + TALH A G+ ++ LL G + G +PLHIA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
A + + LL KGA AV +NG TPLH AA KN+ E A LLE GA +A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 610 TPLHLAAQQGHTEMCALLL 666
T +H AA +G+ +M +LL
Sbjct: 141 TAMHRAAAKGNLKMIHILL 159
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +P+H+AA A +I++ LL GA V A + TPLH A+ +IAV+LL+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 190 RAITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A DHY +H AA + N + L+ + A +G T LHLA ++ A L
Sbjct: 133 DA--KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 364 LLAHGAAPDQAGKNGMTPLHIA 429
L++ GA+ K TPL +A
Sbjct: 191 LVSQGASIYIENKEEKTPLQVA 212
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/104 (34%), Positives = 50/104 (48%)
Frame = +1
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
+LA + + ++ T LH A + LL+ G G +PLHIAA +
Sbjct: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGR 85
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL GA NA ++ G TPLH AA + E+ +LLEGG
Sbjct: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
>AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22206 fis, clone HRC01431. ).
Length = 460
Score = 111 bits (266), Expect = 3e-24
Identities = 80/229 (34%), Positives = 115/229 (50%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL NGA +EA++ R + TPL +A G ++ LLL GA
Sbjct: 79 KGFTPLILAATAGHVGVVEILLGNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGA 138
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G+
Sbjct: 139 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAV 198
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 199 KLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAAS 258
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 259 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRG 307
Score = 109 bits (261), Expect = 1e-23
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 115 DTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 174
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 175 SRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSL 234
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 235 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 294
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LAA GH ++ LL++ G
Sbjct: 295 GHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAG 340
Score = 105 bits (252), Expect = 2e-22
Identities = 69/225 (30%), Positives = 113/225 (50%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H ++++ LL GA++E + ++ TPL +A+ G+V + +LL +GAD+
Sbjct: 48 DTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLGNGADIE 107
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 108 AQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 167
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA A LL+ G+D A + N +T L +A +
Sbjct: 168 NAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQG 227
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 228 RTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 272
Score = 94.3 bits (224), Expect = 4e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+ LLL G+D+
Sbjct: 149 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 208
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 209 NAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 268
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +AA
Sbjct: 269 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANG 327
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ L++ GA +A TPL A ++GH ++ L++
Sbjct: 328 GHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 371
Score = 89.4 bits (212), Expect = 1e-17
Identities = 62/177 (35%), Positives = 92/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
A+L + D+ A T ++H L +A + ++ L+E A + KKGFT L LAA
Sbjct: 29 AMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 88
Query: 334 KYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
G++ V +LL +GA + Q+ + TPL +A +Q V LL +GA+ + + +
Sbjct: 89 TAGHVGVVEILLGNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDY 148
Query: 511 TPLHIAARKNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
TPL +AA + LL GA N+ SK G +PL LAA GHT LLL+ G
Sbjct: 149 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG 205
Score = 83.8 bits (198), Expect = 6e-16
Identities = 61/190 (32%), Positives = 87/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA HT +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 182 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 241
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 242 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 301
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +AA V L++ GAD A TPL A RK
Sbjct: 302 LLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 361
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 362 HVKVVRYLVK 371
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA T+++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 218 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 277
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LAA G+L V LL+
Sbjct: 278 PPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLV 337
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 338 QAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKE 372
Score = 46.0 bits (104), Expect = 1e-04
Identities = 21/56 (37%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LAA H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 316 KGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 371
>AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein.
Length = 2486
Score = 111 bits (266), Expect = 3e-24
Identities = 80/229 (34%), Positives = 115/229 (50%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL NGA +EA++ R + TPL +A G ++ LLL GA
Sbjct: 998 KGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGA 1057
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G+
Sbjct: 1058 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAV 1117
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 1118 KLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAAS 1177
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 1178 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRG 1226
Score = 109 bits (261), Expect = 1e-23
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 1034 DTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 1093
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 1094 SRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSL 1153
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 1154 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 1213
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LAA GH ++ LL++ G
Sbjct: 1214 GHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAG 1259
Score = 107 bits (256), Expect = 5e-23
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G +++A L++ GAD
Sbjct: 384 GYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD 443
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL AA++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 444 IELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 500
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ + A N HT L +A
Sbjct: 501 LQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGH 560
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L AA+ GHT + LL+
Sbjct: 561 LAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 602
Score = 106 bits (254), Expect = 9e-23
Identities = 69/225 (30%), Positives = 113/225 (50%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H ++++ LL GA++E + ++ TPL +A+ G+V + +LL +GAD+
Sbjct: 967 DTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIE 1026
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 1027 AQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 1086
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA A LL+ G+D A + N +T L +A +
Sbjct: 1087 NAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQG 1146
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 1147 RTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1191
Score = 105 bits (252), Expect = 2e-22
Identities = 72/224 (32%), Positives = 116/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A + D++++LL +GA++E TPL A G+V++A LLL++GA +
Sbjct: 218 GNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGI 277
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + ++ L+E A T + TAL A G+++VA LL
Sbjct: 278 NTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 337
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA + V G+TPL AAR+
Sbjct: 338 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHE 397
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G E+ L++ G
Sbjct: 398 EMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAG 441
Score = 105 bits (251), Expect = 2e-22
Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H +++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 286 ESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 345
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLL
Sbjct: 346 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 405
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL AA++ +E
Sbjct: 406 QGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD---IELGCSTPLMEAAQEGHLE 462
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 463 LVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAG 504
Score = 98.7 bits (235), Expect = 2e-20
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ A A H ++ R+LL NGA + + E +++ L +A G++++ LL+ GAD
Sbjct: 251 GHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGAD 310
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 311 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 370
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA+ ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 371 IERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGF 430
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A L++ GA + E TPL AAQ+GH E+ LL G
Sbjct: 431 LEVADFLIKAGA--DIELGCS-TPLMEAAQEGHLELVKYLLAAG 471
Score = 94.7 bits (225), Expect = 3e-19
Identities = 75/223 (33%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA++E E TPL A+R G+ ++ LLL GA++
Sbjct: 352 ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 411
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L AA+ G+L++ LL
Sbjct: 412 AQTEETQETALTLACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLL 468
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 469 AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVC 528
Query: 550 TAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T L+ GA N + T L LA GH + LLL G
Sbjct: 529 TVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 571
Score = 94.3 bits (224), Expect = 4e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+ LLL G+D+
Sbjct: 1068 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1127
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 1128 NAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1187
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +AA
Sbjct: 1188 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANG 1246
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ L++ GA +A TPL A ++GH ++ L++
Sbjct: 1247 GHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1290
Score = 88.6 bits (210), Expect = 2e-17
Identities = 62/177 (35%), Positives = 92/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
A+L + D+ A T ++H L +A + ++ L+E A + KKGFT L LAA
Sbjct: 948 AMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1007
Query: 334 KYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
G++ V +LL +GA + Q+ + TPL +A +Q V LL +GA+ + + +
Sbjct: 1008 TAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDY 1067
Query: 511 TPLHIAARKNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
TPL +AA + LL GA N+ SK G +PL LAA GHT LLL+ G
Sbjct: 1068 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG 1124
Score = 83.8 bits (198), Expect = 6e-16
Identities = 61/190 (32%), Positives = 87/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA HT +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 1101 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 1160
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 1161 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 1220
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +AA V L++ GAD A TPL A RK
Sbjct: 1221 LLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 1280
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 1281 HVKVVRYLVK 1290
Score = 83.0 bits (196), Expect = 1e-15
Identities = 63/180 (35%), Positives = 85/180 (47%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T+
Sbjct: 129 GDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITS 188
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G++K+ LLLAH A + G T L A V LLE GA +
Sbjct: 189 LMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHN 248
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL A +E A LLE GA N S + + L LA +GH EM LLE G
Sbjct: 249 ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAG 308
Score = 74.1 bits (174), Expect = 5e-13
Identities = 63/228 (27%), Positives = 97/228 (42%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 50 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAE 109
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A +D+ + ++ + V LIE + + T++G + L LA G ++A
Sbjct: 110 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRS-VNEHTEEGESLLCLACSAGYYELAQ 168
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +T L AA + LL AD A + G+T L A
Sbjct: 169 VLLAMHANVEDRGIKGDITSLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAG 228
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LLE GA ++ G TPL A GH E+ LLLE G G
Sbjct: 229 GYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAG 276
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA ++ L++ GA +E TPL A++ G++++ LL GA+V
Sbjct: 419 ETALTLACCGGFLEVADFLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVH 475
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G++ L++
Sbjct: 476 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLIS 535
Query: 373 HGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ N T L +A AV LL GAD K+G T L AA+
Sbjct: 536 KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTS 595
Query: 550 TAATLLEY 573
LL+Y
Sbjct: 596 VVCYLLDY 603
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA T+++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 1137 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1196
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LAA G+L V LL+
Sbjct: 1197 PPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLV 1256
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 1257 QAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKE 1291
Score = 64.1 bits (149), Expect = 5e-10
Identities = 43/124 (34%), Positives = 63/124 (50%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G+V L+ G
Sbjct: 478 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 537
Query: 181 ADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V TA++ + L +A + V L+ H A T K G T L AAK G+ V
Sbjct: 538 ANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVV 597
Query: 358 NLLL 369
LL
Sbjct: 598 CYLL 601
Score = 46.0 bits (104), Expect = 1e-04
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A T L +A G++ + LLL HGAD
Sbjct: 514 GRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGAD 573
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
D L AAK + V L+++ L + T L
Sbjct: 574 PTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQL 618
Score = 46.0 bits (104), Expect = 1e-04
Identities = 21/56 (37%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LAA H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 1235 KGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1290
>AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit p28
protein.
Length = 226
Score = 111 bits (266), Expect = 3e-24
Identities = 63/171 (36%), Positives = 90/171 (52%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H A A HT+I+ LL+ G V K +PLHIA+ G +I LL GA V A
Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ + PLH AA ++ H++A L+E A A TA+H AA GNLK+ ++LL +
Sbjct: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
A+ + G TPLH+A ++ A L+ +GA K TPL +A
Sbjct: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 93.1 bits (221), Expect = 9e-19
Identities = 53/157 (33%), Positives = 76/157 (48%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
D LH A + ++ L++ P+ G++ LH+AA G ++ LL GA
Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
+ +NG TPLH AA ++ +A LLE GA+ A T +H AA K ++ L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L Y A TN + G TPLHLA + E LL+ G
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
Score = 91.9 bits (218), Expect = 2e-18
Identities = 58/175 (33%), Positives = 83/175 (47%)
Frame = +1
Query: 103 RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNA 282
++ +T LH A G+ +I LLQ G V ++PLHIAA ++ AL+ A
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
+ A + G T LH AA ++A +LL GA PD T +H AA +
Sbjct: 98 QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
LL A G+TPLH+A + ++E A L+ GA E+K TPL +A
Sbjct: 158 LLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 90.2 bits (214), Expect = 7e-18
Identities = 51/139 (36%), Positives = 74/139 (53%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ +++ + T T + TALH A G+ ++ LL G + G +PLHIA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
A + + LL KGA AV +NG TPLH AA KN+ E A LLE GA +A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 610 TPLHLAAQQGHTEMCALLL 666
T +H AA +G+ +M +LL
Sbjct: 141 TAMHRAAAKGNLKMIHILL 159
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +P+H+AA A +I++ LL GA V A + TPLH A+ +IAV+LL+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 190 RAITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A DHY +H AA + N + L+ + A +G T LHLA ++ A L
Sbjct: 133 DA--KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 364 LLAHGAAPDQAGKNGMTPLHIA 429
L++ GA+ K TPL +A
Sbjct: 191 LVSQGASIYIENKEEKTPLQVA 212
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/104 (34%), Positives = 50/104 (48%)
Frame = +1
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
+LA + + ++ T LH A + LL+ G G +PLHIAA +
Sbjct: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGR 85
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL GA NA ++ G TPLH AA + E+ +LLEGG
Sbjct: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
>AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein
protein.
Length = 520
Score = 110 bits (265), Expect = 4e-24
Identities = 75/225 (33%), Positives = 107/225 (47%), Gaps = 6/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+ L+ HTD + LL GA V+AK + +T LH + G+ + LLQHGA
Sbjct: 120 GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC 179
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA----TTKKGFTALHLAAKYGNLKVA 357
+ P+H++A + V AL++ A + A G+TALH A G+
Sbjct: 180 LLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCV 239
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK-GAD-AKAVAKNGHTPLHIAA 531
LLL G N +PLH A D + A L++ GA A G TPLH AA
Sbjct: 240 ELLLEQEVFQKTEG-NAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAA 298
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ +E LL + A N+ G TPL +AA+ G T +L+
Sbjct: 299 FTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLV 343
Score = 99.5 bits (237), Expect = 1e-20
Identities = 74/226 (32%), Positives = 104/226 (46%), Gaps = 9/226 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGA---AVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
TP+H AA H++ +R+L+ N AV+ + QTPL ++ G+ D LL GA+
Sbjct: 86 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 145
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A LH A + + AL++H A +G T +HL+A G++ V L
Sbjct: 146 VDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGAL 205
Query: 367 LAHGAA----PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
L A+ P A +G T LH A + LLE+ K N +PLH A
Sbjct: 206 LQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEG-NAFSPLHCAVI 264
Query: 535 KNQMETAATLLE-YGA-LTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+ A L++ GA + NA G TPLH AA H E LLL
Sbjct: 265 NDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLL 310
Score = 97.1 bits (231), Expect = 6e-20
Identities = 74/233 (31%), Positives = 109/233 (46%), Gaps = 10/233 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ----TPLHIASRLGNVDIAVLLLQ 174
RG TP+HL+A H ++ LL++ A+++A T LH A G+ LLL+
Sbjct: 185 RGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLE 244
Query: 175 HGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP--LTATTKKGFTALHLAAKYGNL 348
+ + ++PLH A N A LI+ + AT KG T LH AA ++
Sbjct: 245 QEV-FQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHV 303
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG-HTPLHI 525
+ LLL+H A + G TPL +AA+ Q L+ + + N +T LH+
Sbjct: 304 ECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHL 363
Query: 526 AARKNQMETAATLLEY---GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A K +A +LE L NA + A TPLH+AA+ G T + LL G
Sbjct: 364 ACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKG 416
Score = 89.8 bits (213), Expect = 9e-18
Identities = 69/228 (30%), Positives = 104/228 (45%), Gaps = 8/228 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ LAA H + + +L+ GA++ K ++TP+H A+ G+ + LL+ +
Sbjct: 50 GRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEP 109
Query: 187 VRAITADHYN---PLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+ N PL ++ + D +L+ A + A K G TALH A G+ +
Sbjct: 110 QNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECV 169
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA--DAK-AVAKN-GHTPLHI 525
+ LL HGA G TP+H++A V LL+ A DA A A N G+T LH
Sbjct: 170 DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHW 229
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LLE E A F+PLH A + +L++
Sbjct: 230 ACYNGHETCVELLLEQEVFQKTEGNA-FSPLHCAVINDNEGAAEMLID 276
Score = 85.8 bits (203), Expect = 1e-16
Identities = 65/228 (28%), Positives = 100/228 (43%), Gaps = 10/228 (4%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+HLAA H + +L+++ ++ + +TPL +A+ G+V+ +L+ GA +
Sbjct: 19 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-- 76
Query: 196 ITADHY---NPLHIAAKQHNHDVAAALIEHNAPLTAT---TKKGFTALHLAAKYGNLKVA 357
+ D+ P+H AA + + LI + P A G T L L+ G+
Sbjct: 77 LVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 136
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
LL GA D K G T LH A + LL+ GA G TP+H++A
Sbjct: 137 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 196
Query: 538 NQMETAATLLEYGALTNAE----SKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL+ A +A G+T LH A GH LLLE
Sbjct: 197 GHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLE 244
Score = 76.6 bits (180), Expect = 9e-14
Identities = 65/225 (28%), Positives = 93/225 (41%), Gaps = 6/225 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQH-GAD 186
G T +H A H + +LL + + +PLH A N A +L+ GA
Sbjct: 223 GYTALHWACYNGHETCVELLLEQEVFQKTEGNAF-SPLHCAVINDNEGAAEMLIDTLGAS 281
Query: 187 -VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
V A + PLH AA + + L+ HNA + + G T L +AA+ G +
Sbjct: 282 IVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEM 341
Query: 364 LLAHGAAPDQAGKNGM-TPLHIAAQYDQQAVATTLLEKGADAKAV-AKNG--HTPLHIAA 531
L++ +A N T LH+A + A +LEK D + A N TPLH+AA
Sbjct: 342 LVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAA 401
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
R LL GA A + G+TP A C L+
Sbjct: 402 RNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALI 446
Score = 75.4 bits (177), Expect = 2e-13
Identities = 61/191 (31%), Positives = 91/191 (47%), Gaps = 7/191 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRN-GAA-VEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
+P+H A ++ +L+ GA+ V A + +TPLH A+ +V+ LLL H A V
Sbjct: 257 SPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQV 316
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLL 366
++ + PL +AA+ + L+ +A LT TALHLA G+ A L+
Sbjct: 317 NSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLI 376
Query: 367 LAHGAAPDQAGKNG---MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP-LHIAAR 534
L + TPLH+AA+ V LL KGA AV +NG+TP L A
Sbjct: 377 LEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPN 436
Query: 535 KNQMETAATLL 567
K+ + A +L
Sbjct: 437 KDVADCLALIL 447
Score = 67.7 bits (158), Expect = 4e-11
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 6/160 (3%)
Frame = +1
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA--- 384
+PLH+AA +H L++ L G T L LAA G+++ ++L+ GA+
Sbjct: 19 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 78
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA---KNGHTPLHIAARKNQMETA 555
D K TP+H AA L+ AV NG TPL ++ +
Sbjct: 79 KDYILKR--TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 136
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+LL GA +A+ K G T LH A GH E LL+ G
Sbjct: 137 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHG 176
Score = 51.2 bits (117), Expect = 4e-06
Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Frame = +1
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
D + ++PLH+AA + L++ D +G TPL +AA K +E L+
Sbjct: 11 DSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI 70
Query: 568 EYGA-LTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
GA + + TP+H AA GH+E C LL G Q A+
Sbjct: 71 NQGASILVKDYILKRTPIHAAATNGHSE-CLRLLIGNAEPQNAV 113
Score = 30.7 bits (66), Expect = 5.7
Identities = 15/42 (35%), Positives = 28/42 (66%)
Frame = +1
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
MET+ T + L++++++A +PLHLAA GH + +L++
Sbjct: 1 METSGTDM----LSDSDNRATISPLHLAAYHGHHQALEVLVQ 38
>BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein.
Length = 581
Score = 110 bits (264), Expect = 6e-24
Identities = 76/221 (34%), Positives = 112/221 (50%), Gaps = 1/221 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+ A+ + DI+++LL + A V +++ T L A G VDI +LL GA++
Sbjct: 274 TPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIED 333
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPL-TATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PL AA + +VA L++H A + T + + +AL LA G+L + LL
Sbjct: 334 HNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLE 393
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA + T L A VA LL+ GA A + +PL +AA +E
Sbjct: 394 AGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVEL 453
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
AA L+E GA + G+TPL AA++GH EM ALLL G
Sbjct: 454 AALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQG 494
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 85.4 bits (202), Expect = 2e-16
Identities = 68/199 (34%), Positives = 96/199 (48%), Gaps = 1/199 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAG 606
LL G E G
Sbjct: 550 LVKYLLASGQAGGHEDYFG 568
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 110 bits (264), Expect = 6e-24
Identities = 66/195 (33%), Positives = 98/195 (50%)
Frame = +1
Query: 94 AKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIE 273
A R +++ LHIA+ G+V+ VLLL+ GA+ PLH+AA+ + L+E
Sbjct: 60 AFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLE 119
Query: 274 HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
++A + +G TA+H A G ++ + L+ H + D G T LH+A Q +
Sbjct: 120 YSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTT 179
Query: 454 ATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
LL+ GAD +G TPL+ A Q +TA LL GA K G TPL L Q
Sbjct: 180 VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQ 238
Query: 634 QGHTEMCALLLEGGP 678
G+ E C +L++ P
Sbjct: 239 GGYGETCEVLIQYHP 253
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/184 (29%), Positives = 88/184 (47%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AA + + +LL+ GA + TPLH+A+R G LL++ ADV
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ +H A ++ L++H + + G TALH+A + G+ LL GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGA 188
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
++ +G TPL+ A + Q+ A LL +GA KNG TPL + + ET
Sbjct: 189 DINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQGGYGETCEV 247
Query: 562 LLEY 573
L++Y
Sbjct: 248 LIQY 251
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 2/146 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+HLAAR + LL A V E T +H + G ++ L+QH +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
DV A LH+A + + L++ A + G T L+ A +G A +
Sbjct: 156 DVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 215
Query: 364 LLAHGA--APDQAGKNGMTPLHIAAQ 435
LL GA PD KNG+TPL + Q
Sbjct: 216 LLLRGAKYLPD---KNGVTPLDLCVQ 238
>BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 109 bits (262), Expect = 1e-23
Identities = 62/171 (36%), Positives = 89/171 (52%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +H A A HT+I+ LL+ G V K +PLHIA+ G +I LL GA V A
Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ + PLH AA ++ H++A L+E A A TA+H AA GNLK+ ++LL +
Sbjct: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
A+ + G TPLH+A ++ A L+ +G K TPL +A
Sbjct: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIYIENKEEKTPLQVA 212
Score = 93.1 bits (221), Expect = 9e-19
Identities = 53/157 (33%), Positives = 76/157 (48%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
D LH A + ++ L++ P+ G++ LH+AA G ++ LL GA
Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
+ +NG TPLH AA ++ +A LLE GA+ A T +H AA K ++ L
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L Y A TN + G TPLHLA + E LL+ G
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
Score = 90.2 bits (214), Expect = 7e-18
Identities = 51/139 (36%), Positives = 74/139 (53%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ +++ + T T + TALH A G+ ++ LL G + G +PLHIA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
A + + LL KGA AV +NG TPLH AA KN+ E A LLE GA +A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 610 TPLHLAAQQGHTEMCALLL 666
T +H AA +G+ +M +LL
Sbjct: 141 TAMHRAAAKGNLKMIHILL 159
Score = 90.2 bits (214), Expect = 7e-18
Identities = 57/175 (32%), Positives = 82/175 (46%)
Frame = +1
Query: 103 RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNA 282
++ +T LH A G+ +I LLQ G V ++PLHIAA ++ AL+ A
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
+ A + G T LH AA ++A +LL GA PD T +H AA +
Sbjct: 98 QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLA 627
LL A G+TPLH+A + ++E A L+ G E+K TPL +A
Sbjct: 158 LLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIYIENKEEKTPLQVA 212
Score = 77.4 bits (182), Expect = 5e-14
Identities = 50/142 (35%), Positives = 74/142 (52%), Gaps = 2/142 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +P+H+AA A +I++ LL GA V A + TPLH A+ +IAV+LL+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 190 RAITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
A DHY +H AA + N + L+ + A +G T LHLA ++ A L
Sbjct: 133 DA--KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 364 LLAHGAAPDQAGKNGMTPLHIA 429
L++ G + K TPL +A
Sbjct: 191 LVSQGTSIYIENKEEKTPLQVA 212
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/104 (34%), Positives = 50/104 (48%)
Frame = +1
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
+LA + + ++ T LH A + LL+ G G +PLHIAA +
Sbjct: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGR 85
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL GA NA ++ G TPLH AA + E+ +LLEGG
Sbjct: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
>AL080091-1|CAB45706.2| 266|Homo sapiens hypothetical protein
protein.
Length = 266
Score = 109 bits (262), Expect = 1e-23
Identities = 70/219 (31%), Positives = 108/219 (49%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA H +R L+ G AV + +PLH A G++ +LL+HGA V
Sbjct: 42 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 101
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+TAD + PL A + D L++H A + + + +H AA+ G+++ N L+A+
Sbjct: 102 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLIAY 160
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G D + TPL++A + Q+A LLE GA K +PLH AR E A
Sbjct: 161 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGAVVNQ-GKGQDSPLHAVARTASEELA 219
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L+++GA T A++ G P+ L + L EG
Sbjct: 220 CLLMDFGADTQAKNAEGKRPVGLVPPESPLAQLFLEREG 258
Score = 88.2 bits (209), Expect = 3e-17
Identities = 60/191 (31%), Positives = 89/191 (46%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
+P+H A+ G+ L+ G V ITADH +PLH A + L++H A +
Sbjct: 42 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 101
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T T L A G+ NLLL HGA+ Q + +P+H AA+ +L+
Sbjct: 102 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAY 160
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
G + + TPL++A Q LLE GA+ N + K +PLH A+ E+
Sbjct: 161 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGAVVN-QGKGQDSPLHAVARTASEELA 219
Query: 655 ALLLEGGPGTQ 687
LL++ G TQ
Sbjct: 220 CLLMDFGADTQ 230
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Frame = +1
Query: 211 YNPLHIAAKQHNHDVAAA-LIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
++P+H AA H H ++ LI + T + LH A G+L +LL HGA
Sbjct: 41 WSPMHEAAI-HGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQV 99
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+ + TPL A LL+ GA + + +P+H AAR+ +E +L+
Sbjct: 100 NGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLI 158
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
YG + + TPL+LA + LLE G
Sbjct: 159 AYGGNIDHKISHLGTPLYLACENQQRACVKKLLESG 194
Score = 58.4 bits (135), Expect = 2e-08
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Frame = +1
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
PL ++ +H AA +G+ L++ G A + + ++PLH A +
Sbjct: 32 PLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKI 91
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ GA V + HTPL A + LL++GA ES +P+H AA++GH
Sbjct: 92 LLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGH 150
Query: 643 TE-MCALLLEGG 675
E + +L+ GG
Sbjct: 151 VECVNSLIAYGG 162
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 108 bits (259), Expect = 2e-23
Identities = 63/220 (28%), Positives = 103/220 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T H AA D + L+ +G K +E T LH+A+ G++ + L+ G D+
Sbjct: 68 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 127
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ LH AA + D L+ + + A T+K + LH AA G+ V+ +L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + G +PLH+A +++ A+ L+ +D AV TPLH+AA +
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 247
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL G N K G T L +A + H + ++++
Sbjct: 248 IADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMIIK 287
Score = 90.6 bits (215), Expect = 5e-18
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN--GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
G T +H AA+ H ++ ++ + A++ + +T H A+ G +D L+ G
Sbjct: 33 GLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGC 92
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
D + LH+AA + + V L++ L +G TALH AA + L
Sbjct: 93 DHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQL 152
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL G+ + + ++ LH AA + V+ L+ G A V G +PLH+A R N
Sbjct: 153 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 212
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ + NA TPLHLAA+ ++ +LL G
Sbjct: 213 PALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 256
Score = 65.7 bits (153), Expect = 2e-10
Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA- 492
AL L+A +G+L++ +L+ GA K+G+T LH AAQ V ++E D
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 493 -VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
V K G T H AA Q++ L+ G N + K G T LHLAA +GH + L++
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Query: 670 GG 675
G
Sbjct: 123 IG 124
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/89 (30%), Positives = 48/89 (53%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G +P+HLA R N ++R+L+ + + V A +QTPLH+A+ DIA +LL G D
Sbjct: 199 QGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIE 273
+ L +A + ++ + +I+
Sbjct: 259 LNLRDKQGKTALAVAVRSNHVSLVDMIIK 287
>AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein
protein.
Length = 968
Score = 108 bits (259), Expect = 2e-23
Identities = 78/229 (34%), Positives = 114/229 (49%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL G +EA++ R + TPL +A G ++ LLL GA
Sbjct: 581 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 640
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G++
Sbjct: 641 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 700
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 701 KLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAAS 760
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 761 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRG 809
Score = 107 bits (257), Expect = 4e-23
Identities = 75/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 617 DTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 676
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 677 SRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSL 736
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 737 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 796
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LA+ GH ++ LL++ G
Sbjct: 797 GHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAG 842
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/225 (28%), Positives = 108/225 (48%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H +++ +L+ A +E + ++ TPL +A+ G+V + +LL G D+
Sbjct: 550 DTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIE 609
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 610 AQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 669
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA LL+ G+D A + N +T L +A +
Sbjct: 670 NAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQG 729
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 730 RAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 774
Score = 94.7 bits (225), Expect = 3e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+V LLL G+D+
Sbjct: 651 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 710
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 711 NAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 770
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +A+
Sbjct: 771 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 829
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L++ GA +A TPL A ++GH ++ L++
Sbjct: 830 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 873
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +1
Query: 184 DVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D+ A T ++H L +A + ++ + LI +A + KKGFT L LAA G++ V
Sbjct: 540 DIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVE 599
Query: 361 LLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + Q+ + TPL +A +Q V LL +GA+ + + +TPL +AA
Sbjct: 600 ILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 659
Query: 538 NQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL GA N+ SK G +PL LAA GH LLL+ G
Sbjct: 660 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMG 707
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA H +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 684 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 743
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 744 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 803
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +A+ V L++ GAD A TPL A RK
Sbjct: 804 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 863
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 864 HVKVVQYLVK 873
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA +++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 720 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 779
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LA+ G+ V LL+
Sbjct: 780 PPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV 839
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 840 QAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKE 874
Score = 63.3 bits (147), Expect = 9e-10
Identities = 55/186 (29%), Positives = 82/186 (44%), Gaps = 1/186 (0%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPL AS+ G++++ LL GA+V A TA L A + + DVA L++ A L
Sbjct: 12 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLD- 70
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
K ++K + + + G TPL AA+ L+ K
Sbjct: 71 -------------KQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISK 117
Query: 475 GADA-KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
GA+ +A A N HT + +A + LL +GA K G T L AA+ GHT +
Sbjct: 118 GANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNV 177
Query: 652 CALLLE 669
+ LL+
Sbjct: 178 VSYLLD 183
Score = 61.7 bits (143), Expect = 3e-09
Identities = 55/187 (29%), Positives = 83/187 (44%), Gaps = 1/187 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+ A++ H ++++ LL +GA V A T L A G+ D+A +LLQ GAD+
Sbjct: 12 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-- 69
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
KQ + I+ ++ G T L AA+ G+L L++
Sbjct: 70 ------------DKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISK 117
Query: 376 GAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA ++A N T + +A AV LL GAD K+G T L AA+
Sbjct: 118 GANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNV 177
Query: 553 AATLLEY 573
+ LL+Y
Sbjct: 178 VSYLLDY 184
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A A T + +A G++ + LLL HGAD
Sbjct: 95 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 154
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH 276
D L AAK + +V + L+++
Sbjct: 155 PTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 184
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LA+ H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 818 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 873
>AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein.
Length = 1486
Score = 108 bits (259), Expect = 2e-23
Identities = 78/229 (34%), Positives = 114/229 (49%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL G +EA++ R + TPL +A G ++ LLL GA
Sbjct: 1120 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 1179
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G++
Sbjct: 1180 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 1239
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 1240 KLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAAS 1299
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 1300 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRG 1348
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 319 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 378
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 379 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 438
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 439 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 498
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 499 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 542
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 387 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 446
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 447 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 506
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 507 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 563
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 564 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 605
Score = 107 bits (257), Expect = 4e-23
Identities = 75/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 1156 DTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 1215
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 1216 SRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSL 1275
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 1276 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 1335
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LA+ GH ++ LL++ G
Sbjct: 1336 GHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAG 1381
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/225 (28%), Positives = 108/225 (48%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H +++ +L+ A +E + ++ TPL +A+ G+V + +LL G D+
Sbjct: 1089 DTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIE 1148
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 1149 AQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 1208
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA LL+ G+D A + N +T L +A +
Sbjct: 1209 NAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQG 1268
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 1269 RAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1313
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 352 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 411
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 412 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 471
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 472 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 531
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 532 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 572
Score = 94.7 bits (225), Expect = 3e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+V LLL G+D+
Sbjct: 1190 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1249
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 1250 NAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1309
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +A+
Sbjct: 1310 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 1368
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L++ GA +A TPL A ++GH ++ L++
Sbjct: 1369 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1412
Score = 89.4 bits (212), Expect = 1e-17
Identities = 75/241 (31%), Positives = 115/241 (47%), Gaps = 21/241 (8%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 485 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 544
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 545 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 601
Query: 367 LAHGAAPDQ-------------------AGKNGMTPLHIAAQYDQQAVATTLLEKGADA- 486
L GA D+ + G TPL AA+ L+ KGA+
Sbjct: 602 LQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVN 661
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+A A N HT + +A + LL +GA K G T L AA+ GHT + + LL
Sbjct: 662 RATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 721
Query: 667 E 669
+
Sbjct: 722 D 722
Score = 86.2 bits (204), Expect = 1e-16
Identities = 71/235 (30%), Positives = 110/235 (46%), Gaps = 20/235 (8%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A H ++ R+LL +GA V A ++PL +A+ G+V++A LL++ GA++ + +
Sbjct: 426 ACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG 485
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANLLLAHGAAP 387
Y PL AA++ + ++ A L+ A + A T++ TAL LA G +VA+ L+ GA
Sbjct: 486 YTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI 545
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+ TPL A+Q + LL GA+ A G T L A + A LL
Sbjct: 546 ELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLL 602
Query: 568 EYGALTNA-------------------ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ GA + ES+ G TPL AA+ GH L+ G
Sbjct: 603 QAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKG 657
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +1
Query: 184 DVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D+ A T ++H L +A + ++ + LI +A + KKGFT L LAA G++ V
Sbjct: 1079 DIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVE 1138
Query: 361 LLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + Q+ + TPL +A +Q V LL +GA+ + + +TPL +AA
Sbjct: 1139 ILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 1198
Query: 538 NQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL GA N+ SK G +PL LAA GH LLL+ G
Sbjct: 1199 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMG 1246
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA H +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 1223 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 1282
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 1283 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 1342
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +A+ V L++ GAD A TPL A RK
Sbjct: 1343 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 1402
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 1403 HVKVVQYLVK 1412
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 230 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 289
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 290 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 349
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 350 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 409
Score = 76.6 bits (180), Expect = 9e-14
Identities = 75/242 (30%), Positives = 108/242 (44%), Gaps = 21/242 (8%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 453 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 512
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 513 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 569
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA------DAKAV------------ 495
A GA G T L A + VA LL+ GA D K +
Sbjct: 570 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEH 629
Query: 496 -AKNGHTPLHIAARKNQMETAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLE 669
++ G TPL AAR + T L+ GA N A + T + LA GH + LLL
Sbjct: 630 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLA 689
Query: 670 GG 675
G
Sbjct: 690 HG 691
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA +++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 1259 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1318
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LA+ G+ V LL+
Sbjct: 1319 PPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV 1378
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 1379 QAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKE 1413
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 151 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 210
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 211 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 269
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 270 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 329
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 330 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 377
Score = 61.7 bits (143), Expect = 3e-09
Identities = 55/187 (29%), Positives = 83/187 (44%), Gaps = 1/187 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+ A++ H ++++ LL +GA V A T L A G+ D+A +LLQ GAD+
Sbjct: 551 TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLD- 609
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
KQ + I+ ++ G T L AA+ G+L L++
Sbjct: 610 -------------KQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISK 656
Query: 376 GAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA ++A N T + +A AV LL GAD K+G T L AA+
Sbjct: 657 GANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNV 716
Query: 553 AATLLEY 573
+ LL+Y
Sbjct: 717 VSYLLDY 723
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A A T + +A G++ + LLL HGAD
Sbjct: 634 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH 276
D L AAK + +V + L+++
Sbjct: 694 PTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 723
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LA+ H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 1357 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1412
>AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens
cDNA FLJ20288 fis, clone HEP04414. ).
Length = 686
Score = 108 bits (259), Expect = 2e-23
Identities = 78/229 (34%), Positives = 114/229 (49%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL G +EA++ R + TPL +A G ++ LLL GA
Sbjct: 298 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 357
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G++
Sbjct: 358 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 417
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 418 KLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAAS 477
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 478 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRG 526
Score = 107 bits (257), Expect = 4e-23
Identities = 75/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 334 DTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 393
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 394 SRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSL 453
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 454 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 513
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LA+ GH ++ LL++ G
Sbjct: 514 GHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAG 559
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/225 (28%), Positives = 108/225 (48%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H +++ +L+ A +E + ++ TPL +A+ G+V + +LL G D+
Sbjct: 267 DTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIE 326
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 327 AQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 386
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA LL+ G+D A + N +T L +A +
Sbjct: 387 NAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQG 446
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 447 RAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 491
Score = 94.7 bits (225), Expect = 3e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+V LLL G+D+
Sbjct: 368 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 427
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 428 NAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 487
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +A+
Sbjct: 488 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 546
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L++ GA +A TPL A ++GH ++ L++
Sbjct: 547 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 590
Score = 82.6 bits (195), Expect = 1e-15
Identities = 59/168 (35%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +1
Query: 184 DVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV A T ++H L +A + ++ + LI +A + KKGFT L LAA G++ V
Sbjct: 257 DVDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVE 316
Query: 361 LLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + Q+ + TPL +A +Q V LL +GA+ + + +TPL +AA
Sbjct: 317 ILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 376
Query: 538 NQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL GA N+ SK G +PL LAA GH LLL+ G
Sbjct: 377 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMG 424
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA H +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 401 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 460
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 461 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 520
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +A+ V L++ GAD A TPL A RK
Sbjct: 521 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 580
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 581 HVKVVQYLVK 590
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA +++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 437 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 496
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LA+ G+ V LL+
Sbjct: 497 PPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV 556
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 557 QAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKE 591
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 1/181 (0%)
Frame = +1
Query: 130 ASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG 309
AS+ G++++ LL GA+V A TA L A + + DVA L++ A L
Sbjct: 3 ASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLD------ 56
Query: 310 FTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA- 486
K ++K + + + G TPL AA+ L+ KGA+
Sbjct: 57 --------KQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVN 108
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
+A A N HT + +A + LL +GA K G T L AA+ GHT + + LL
Sbjct: 109 RATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 168
Query: 667 E 669
+
Sbjct: 169 D 169
Score = 58.4 bits (135), Expect = 2e-08
Identities = 53/182 (29%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A++ H ++++ LL +GA V A T L A G+ D+A +LLQ GAD+
Sbjct: 3 ASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL------- 55
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
KQ + I+ ++ G T L AA+ G+L L++ GA +
Sbjct: 56 -------DKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVN 108
Query: 391 QA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+A N T + +A AV LL GAD K+G T L AA+ + LL
Sbjct: 109 RATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 168
Query: 568 EY 573
+Y
Sbjct: 169 DY 170
Score = 56.8 bits (131), Expect = 8e-08
Identities = 63/243 (25%), Positives = 100/243 (41%), Gaps = 21/243 (8%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A A T + +A G++ + LLL HGAD
Sbjct: 81 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 140
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH-----NAPLTATTK------------KGFT 315
D L AAK + +V + L+++ + P T ++ +
Sbjct: 141 PTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSVPTTDVSQLPPPSQDQSQEPDRTS 200
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL--LEKGADAK 489
+ A G K + + G+ +TP +Q + ++ + D
Sbjct: 201 QENSPALLGVQKAVSTRVPTGSNSSSQTTECLTP-ESCSQTTSNVASQSMPPVYPSVDVD 259
Query: 490 AVAKNGH-TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A ++ H T L +A E + L+ A K GFTPL LAA GH + +LL
Sbjct: 260 AHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILL 319
Query: 667 EGG 675
+ G
Sbjct: 320 DKG 322
Score = 46.8 bits (106), Expect = 8e-05
Identities = 43/143 (30%), Positives = 66/143 (46%), Gaps = 20/143 (13%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVE--------------AKARERQ-----TPL 123
T G+T + A HTD+ +LL+ GA ++ AK +E + TPL
Sbjct: 26 TATGDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPL 85
Query: 124 HIASRLGNVDIAVLLLQHGADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
A+R G++ L+ GA+V TA++ + + +A + V L+ H A T
Sbjct: 86 MKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRL 145
Query: 301 KKGFTALHLAAKYGNLKVANLLL 369
K G T L AAK G+ V + LL
Sbjct: 146 KDGSTMLIEAAKGGHTNVVSYLL 168
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LA+ H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 535 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 590
>AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 2 protein.
Length = 2617
Score = 108 bits (259), Expect = 2e-23
Identities = 78/229 (34%), Positives = 114/229 (49%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL G +EA++ R + TPL +A G ++ LLL GA
Sbjct: 1087 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 1146
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G++
Sbjct: 1147 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 1206
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 1207 KLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAAS 1266
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 1267 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRG 1315
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 107 bits (257), Expect = 4e-23
Identities = 75/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 1123 DTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 1182
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 1183 SRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSL 1242
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 1243 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 1302
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LA+ GH ++ LL++ G
Sbjct: 1303 GHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAG 1348
Score = 106 bits (254), Expect = 9e-23
Identities = 74/222 (33%), Positives = 114/222 (51%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ +A A N HT + +A
Sbjct: 588 LQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGH 647
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L AA+ GHT + + LL+
Sbjct: 648 LAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 689
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/225 (28%), Positives = 108/225 (48%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H +++ +L+ A +E + ++ TPL +A+ G+V + +LL G D+
Sbjct: 1056 DTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIE 1115
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 1116 AQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 1175
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA LL+ G+D A + N +T L +A +
Sbjct: 1176 NAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQG 1235
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 1236 RAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1280
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 94.7 bits (225), Expect = 3e-19
Identities = 74/223 (33%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLC 615
Query: 550 TAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T L+ GA N A + T + LA GH + LLL G
Sbjct: 616 TVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHG 658
Score = 94.7 bits (225), Expect = 3e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+V LLL G+D+
Sbjct: 1157 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1216
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 1217 NAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1276
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +A+
Sbjct: 1277 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 1335
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L++ GA +A TPL A ++GH ++ L++
Sbjct: 1336 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1379
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +1
Query: 184 DVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D+ A T ++H L +A + ++ + LI +A + KKGFT L LAA G++ V
Sbjct: 1046 DIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVE 1105
Query: 361 LLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + Q+ + TPL +A +Q V LL +GA+ + + +TPL +AA
Sbjct: 1106 ILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 1165
Query: 538 NQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL GA N+ SK G +PL LAA GH LLL+ G
Sbjct: 1166 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMG 1213
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA H +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 1190 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 1249
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 1250 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 1309
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +A+ V L++ GAD A TPL A RK
Sbjct: 1310 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 1369
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 1370 HVKVVQYLVK 1379
Score = 78.6 bits (185), Expect = 2e-14
Identities = 60/188 (31%), Positives = 91/188 (48%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA +++ L++ GA +E TPL AS+ G++++ LL GA+V
Sbjct: 506 ETALTLACCGGFSEVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVH 562
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G+L L++
Sbjct: 563 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLIS 622
Query: 373 HGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++A N T + +A AV LL GAD K+G T L AA+
Sbjct: 623 KGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTN 682
Query: 550 TAATLLEY 573
+ LL+Y
Sbjct: 683 VVSYLLDY 690
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA +++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 1226 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1285
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LA+ G+ V LL+
Sbjct: 1286 PPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV 1345
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 1346 QAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKE 1380
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 63.3 bits (147), Expect = 9e-10
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G++ L+ G
Sbjct: 565 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKG 624
Query: 181 ADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V TA++ + + +A + V L+ H A T K G T L AAK G+ V
Sbjct: 625 ANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVV 684
Query: 358 NLLL 369
+ LL
Sbjct: 685 SYLL 688
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A A T + +A G++ + LLL HGAD
Sbjct: 601 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 660
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH 276
D L AAK + +V + L+++
Sbjct: 661 PTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LA+ H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 1324 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1379
>AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 1 protein.
Length = 2542
Score = 108 bits (259), Expect = 2e-23
Identities = 78/229 (34%), Positives = 114/229 (49%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL G +EA++ R + TPL +A G ++ LLL GA
Sbjct: 1087 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 1146
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G++
Sbjct: 1147 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 1206
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 1207 KLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAAS 1266
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 1267 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRG 1315
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 107 bits (257), Expect = 4e-23
Identities = 75/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 1123 DTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 1182
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 1183 SRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSL 1242
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 1243 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 1302
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LA+ GH ++ LL++ G
Sbjct: 1303 GHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAG 1348
Score = 106 bits (254), Expect = 9e-23
Identities = 74/222 (33%), Positives = 114/222 (51%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ +A A N HT + +A
Sbjct: 588 LQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGH 647
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L AA+ GHT + + LL+
Sbjct: 648 LAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 689
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/225 (28%), Positives = 108/225 (48%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H +++ +L+ A +E + ++ TPL +A+ G+V + +LL G D+
Sbjct: 1056 DTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIE 1115
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 1116 AQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 1175
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA LL+ G+D A + N +T L +A +
Sbjct: 1176 NAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQG 1235
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 1236 RAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1280
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 94.7 bits (225), Expect = 3e-19
Identities = 74/223 (33%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLC 615
Query: 550 TAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T L+ GA N A + T + LA GH + LLL G
Sbjct: 616 TVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHG 658
Score = 94.7 bits (225), Expect = 3e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+V LLL G+D+
Sbjct: 1157 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1216
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 1217 NAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1276
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +A+
Sbjct: 1277 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 1335
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L++ GA +A TPL A ++GH ++ L++
Sbjct: 1336 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1379
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +1
Query: 184 DVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D+ A T ++H L +A + ++ + LI +A + KKGFT L LAA G++ V
Sbjct: 1046 DIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVE 1105
Query: 361 LLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + Q+ + TPL +A +Q V LL +GA+ + + +TPL +AA
Sbjct: 1106 ILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 1165
Query: 538 NQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL GA N+ SK G +PL LAA GH LLL+ G
Sbjct: 1166 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMG 1213
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA H +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 1190 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 1249
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 1250 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 1309
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +A+ V L++ GAD A TPL A RK
Sbjct: 1310 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 1369
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 1370 HVKVVQYLVK 1379
Score = 78.6 bits (185), Expect = 2e-14
Identities = 60/188 (31%), Positives = 91/188 (48%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA +++ L++ GA +E TPL AS+ G++++ LL GA+V
Sbjct: 506 ETALTLACCGGFSEVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVH 562
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G+L L++
Sbjct: 563 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLIS 622
Query: 373 HGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++A N T + +A AV LL GAD K+G T L AA+
Sbjct: 623 KGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTN 682
Query: 550 TAATLLEY 573
+ LL+Y
Sbjct: 683 VVSYLLDY 690
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA +++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 1226 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1285
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LA+ G+ V LL+
Sbjct: 1286 PPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV 1345
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 1346 QAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKE 1380
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 63.3 bits (147), Expect = 9e-10
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G++ L+ G
Sbjct: 565 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKG 624
Query: 181 ADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V TA++ + + +A + V L+ H A T K G T L AAK G+ V
Sbjct: 625 ANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVV 684
Query: 358 NLLL 369
+ LL
Sbjct: 685 SYLL 688
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A A T + +A G++ + LLL HGAD
Sbjct: 601 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 660
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH 276
D L AAK + +V + L+++
Sbjct: 661 PTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LA+ H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 1324 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1379
>AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein
protein.
Length = 532
Score = 108 bits (259), Expect = 2e-23
Identities = 78/229 (34%), Positives = 114/229 (49%), Gaps = 6/229 (2%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGA 183
+G TP+ LAA A H ++ ILL G +EA++ R + TPL +A G ++ LLL GA
Sbjct: 164 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 223
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVA 357
+ Y PL +AA ++ L+ A + + T K G + L LAA G++
Sbjct: 224 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 283
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL G+ + Q N T L +A + V + LL++ A+ + AK G TPL AA
Sbjct: 284 KLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAAS 343
Query: 535 KNQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
E LL+ GA NA + T L +AA +GH + C LL+ G
Sbjct: 344 GGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRG 392
Score = 107 bits (257), Expect = 4e-23
Identities = 75/226 (33%), Positives = 112/226 (49%), Gaps = 5/226 (2%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+ LA +++ +LL GA E + TPL +A+ G V+I +LL GA++
Sbjct: 200 DTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 259
Query: 193 AITADHY--NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLKVANL 363
+ T +PL +AA + L++ + + A + TAL LA G +V +L
Sbjct: 260 SRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSL 319
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA--VAKNGHTPLHIAARK 537
LL A + K G+TPL AA V LL+KGAD A V + T L IAA K
Sbjct: 320 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADK 379
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ L+ GA + +K G TPL LA+ GH ++ LL++ G
Sbjct: 380 GHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAG 425
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/225 (28%), Positives = 108/225 (48%), Gaps = 4/225 (1%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+T + LA H +++ +L+ A +E + ++ TPL +A+ G+V + +LL G D+
Sbjct: 133 DTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIE 192
Query: 193 AIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + PL +A +V L+ A +T L LAA G + + +LL
Sbjct: 193 AQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 252
Query: 370 AHGAAPDQ--AGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKN 540
GA + K G++PL +AA LL+ G+D A + N +T L +A +
Sbjct: 253 NAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQG 312
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ E + LL+ A +K G TPL AA G+ E+ +LL+ G
Sbjct: 313 RAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 357
Score = 94.7 bits (225), Expect = 3e-19
Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 6/224 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIAVLLLQHGADV 189
TP+ LAA + +II+ILL GA + ++ + +PL +A+ G+V LLL G+D+
Sbjct: 234 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 293
Query: 190 RA-ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A I + L +A Q +V + L++ A + K G T L AA G +V +L
Sbjct: 294 NAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 353
Query: 367 LAHGA---APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
L GA AP T L IAA L+ +GA K G+TPL +A+
Sbjct: 354 LDKGADVNAPPVPSSRD-TALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 412
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L++ GA +A TPL A ++GH ++ L++
Sbjct: 413 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 456
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +1
Query: 184 DVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D+ A T ++H L +A + ++ + LI +A + KKGFT L LAA G++ V
Sbjct: 123 DIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVE 182
Query: 361 LLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + Q+ + TPL +A +Q V LL +GA+ + + +TPL +AA
Sbjct: 183 ILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASG 242
Query: 538 NQMETAATLLEYGALTNAE--SKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL GA N+ SK G +PL LAA GH LLL+ G
Sbjct: 243 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMG 290
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKAR-ERQTPLHIASRLGNVDIAVLLLQHGAD 186
G +P+ LAA H +++LL G+ + A+ R T L +A G ++ LLL A+
Sbjct: 267 GISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKAN 326
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA--TTKKGFTALHLAAKYGNLKVAN 360
V PL AA +V L++ A + A TAL +AA G+ K
Sbjct: 327 VEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCE 386
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
LL+ GA D K G TPL +A+ V L++ GAD A TPL A RK
Sbjct: 387 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 446
Query: 541 QMETAATLLE 570
++ L++
Sbjct: 447 HVKVVQYLVK 456
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T + LA +++ +LL A VE +A+ TPL A+ G ++ +LL GADV A
Sbjct: 303 TALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 362
Query: 196 --ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + L IAA + ++ LI A + KKG T L LA+ G+ V LL+
Sbjct: 363 PPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLV 422
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
GA D A +TPL A + V L+++
Sbjct: 423 QAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKE 457
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ 174
+G TP+ LA+ H D++++L++ GA V+A + TPL A R G+V + L++
Sbjct: 401 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 456
>AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein.
Length = 1864
Score = 108 bits (259), Expect = 2e-23
Identities = 70/190 (36%), Positives = 90/190 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GET + AA ++ R+LL GAAV R PL R G+ I LLL HGADV
Sbjct: 908 GETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADV 967
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PL +AA + + L+ A + K+G TAL A G+L V L+
Sbjct: 968 NMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLV 1027
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GAA D A KNG TPL +AA Y V L++ GA + V +G PL A
Sbjct: 1028 DNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTS 1087
Query: 550 TAATLLEYGA 579
TLL+ GA
Sbjct: 1088 VVVTLLKKGA 1097
Score = 89.4 bits (212), Expect = 1e-17
Identities = 58/188 (30%), Positives = 88/188 (46%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
+T L A+ G +++ LLL+ GA V PL +Q + + L+ H A +
Sbjct: 909 ETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVN 968
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
K+G T L +AA G+L + LLA GA+ K G+T L A +V +L++
Sbjct: 969 MADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVD 1028
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
GA KNG TPL +AA E L+++GA+ +G PL A +T +
Sbjct: 1029 NGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSV 1088
Query: 652 CALLLEGG 675
LL+ G
Sbjct: 1089 VVTLLKKG 1096
Score = 85.8 bits (203), Expect = 1e-16
Identities = 51/158 (32%), Positives = 78/158 (49%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG P+ R H I+ +LL +GA V ++ +TPL +A+ G++ LL GA
Sbjct: 940 RGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGAS 999
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L A + + V +L+++ A K G T L LAA YG+ +V L
Sbjct: 1000 IALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 1059
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA 480
+ HGA + +GM PL A +V TLL+KGA
Sbjct: 1060 VDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGA 1097
Score = 79.8 bits (188), Expect = 9e-15
Identities = 70/245 (28%), Positives = 101/245 (41%), Gaps = 17/245 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ----- 174
G TP+ AA A + I+ +L + A V+ + Q L A+ G++++ L+Q
Sbjct: 792 GLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTM 851
Query: 175 HGADVRAITADH--YNPLHIAAKQHNHDVAAALIE---------HNAPLTATTKK-GFTA 318
G H L AA ++ + L++ A + + G TA
Sbjct: 852 AGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETA 911
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G L+V LLL GAA Q + G PL + + LL GAD
Sbjct: 912 LTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD 971
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
K G TPL +AA + + T LL GA K G T L A +GH + L++ G
Sbjct: 972 KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGA 1031
Query: 679 GTQFA 693
T A
Sbjct: 1032 ATDHA 1036
Score = 66.1 bits (154), Expect = 1e-10
Identities = 64/227 (28%), Positives = 97/227 (42%), Gaps = 17/227 (7%)
Frame = +1
Query: 46 HTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLH 225
+T+++ +LL GA V+A + TPL A+ G + I VLL + A V + + L
Sbjct: 771 YTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALV 830
Query: 226 IAAKQHNHDVAAALIEHNAPLTATTKKGF-------TALHLAAKYGNLKVANLLLAHGAA 384
AA + + +V LI+ + + + F AL AA G ++ + LL
Sbjct: 831 HAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEK 890
Query: 385 PDQAGKN----------GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
++ + G T L AA + V LLE+GA + G PL R
Sbjct: 891 DEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVR 950
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ + LL +GA N K G TPL +AA +GH LL G
Sbjct: 951 QGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQG 997
Score = 51.2 bits (117), Expect = 4e-06
Identities = 56/196 (28%), Positives = 81/196 (41%), Gaps = 19/196 (9%)
Frame = +1
Query: 145 NVDIAVLLLQHGADVRAITADHYNPLHIAAKQH--NHDVAAALIEHNAPLTATTKKGFTA 318
N+ ++ LL+ GA++ T N + + H ++ A L+E A + A+++ G T
Sbjct: 736 NIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTP 795
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE----KGADA 486
L AA G L + LL A D KNG L AA V L++
Sbjct: 796 LGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQ 855
Query: 487 KAVAKNGHT---PLHIAARKNQMETAATLL----------EYGALTNAESKAGFTPLHLA 627
+ V K H L AA E + LL E + + +S G T L A
Sbjct: 856 QGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAA 915
Query: 628 AQQGHTEMCALLLEGG 675
A +G E+C LLLE G
Sbjct: 916 AGRGKLEVCRLLLEQG 931
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/97 (27%), Positives = 45/97 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A H ++R L+ NGAA + + +TPL +A+ G+ ++ L+ HGA +
Sbjct: 1007 GLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMI 1066
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
+ PL A N V L++ A + T
Sbjct: 1067 EHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPAT 1103
>BC150486-1|AAI50487.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 588 LQAGADLDK 596
>BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 588 LQAGADLDK 596
>BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 588 LQAGADLDK 596
>BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 74.5 bits (175), Expect = 4e-13
Identities = 57/180 (31%), Positives = 83/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 65.3 bits (152), Expect = 2e-10
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRMTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 588 LQAGADLDK 596
>BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH domain
containing 1 protein.
Length = 616
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 362 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 421
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 422 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 481
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 482 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 538
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 539 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 580
Score = 103 bits (248), Expect = 5e-22
Identities = 77/227 (33%), Positives = 111/227 (48%), Gaps = 2/227 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQH 177
T GE+ + LA A + ++ ++LL A VE + + TPL AS G +DI LLL H
Sbjct: 224 TEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLH 283
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
ADV + +A L A D+ L+ A + + G T L AA G+++VA
Sbjct: 284 DADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVA 343
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL HGA + + + + L +A + LLE GAD + HT L A
Sbjct: 344 RVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACM 403
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ GA N + + +PL LAA GH E+ ALL+E G
Sbjct: 404 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERG 450
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 327 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 386
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 387 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 446
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 447 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 506
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 507 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 547
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 205 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 264
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 265 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 324
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 325 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 384
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 428 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 487
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 488 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 544
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 545 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 582
Score = 66.1 bits (154), Expect = 1e-10
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 1/140 (0%)
Frame = +1
Query: 265 LIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA-HGAAPDQAGKNGMTPLHIAAQYD 441
L++ + T++G + L LA G ++A +LLA H D+ K +TPL A+
Sbjct: 213 LLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGG 272
Query: 442 QQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
+ LL AD + + G+T L A ++ LL GA ++ G TPL
Sbjct: 273 YLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLM 332
Query: 622 LAAQQGHTEMCALLLEGGPG 681
AA GH E+ +LL+ G G
Sbjct: 333 EAASAGHVEVARVLLDHGAG 352
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 460 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 519
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 520 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 576
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 577 LQAGADLDK 585
>BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 588 LQAGADLDK 596
>AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ11979 fis, clone HEMBB1001282, weakly similar to
ANKYRIN R. ).
Length = 435
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 181 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 240
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 241 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 300
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 301 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 357
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 358 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 399
Score = 103 bits (248), Expect = 5e-22
Identities = 77/227 (33%), Positives = 111/227 (48%), Gaps = 2/227 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQH 177
T GE+ + LA A + ++ ++LL A VE + + TPL AS G +DI LLL H
Sbjct: 43 TEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLH 102
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
ADV + +A L A D+ L+ A + + G T L AA G+++VA
Sbjct: 103 DADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVA 162
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL HGA + + + + L +A + LLE GAD + HT L A
Sbjct: 163 RVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACM 222
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ GA N + + +PL LAA GH E+ ALL+E G
Sbjct: 223 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERG 269
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 146 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 205
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 206 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 265
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 266 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 325
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 326 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 366
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 24 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 83
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 84 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 143
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 144 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 203
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 247 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 306
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 307 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 363
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 364 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 401
Score = 66.1 bits (154), Expect = 1e-10
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 1/140 (0%)
Frame = +1
Query: 265 LIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA-HGAAPDQAGKNGMTPLHIAAQYD 441
L++ + T++G + L LA G ++A +LLA H D+ K +TPL A+
Sbjct: 32 LLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGG 91
Query: 442 QQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
+ LL AD + + G+T L A ++ LL GA ++ G TPL
Sbjct: 92 YLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLM 151
Query: 622 LAAQQGHTEMCALLLEGGPG 681
AA GH E+ +LL+ G G
Sbjct: 152 EAASAGHVEVARVLLDHGAG 171
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 279 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 338
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 339 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 395
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 396 LQAGADLDK 404
>AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein.
Length = 627
Score = 107 bits (257), Expect = 4e-23
Identities = 74/224 (33%), Positives = 115/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A DI+++LL GA +E TPL A+ G+V++A +LL HGA +
Sbjct: 305 GNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGI 364
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + D+ L+E A T + TAL A G+++VA LL
Sbjct: 365 NTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA+ + V G+TPL AAR+
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHE 484
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G +E+ L++ G
Sbjct: 485 EMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAG 528
Score = 107 bits (257), Expect = 4e-23
Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H D++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 373 ESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 432
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLLA
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL A+++ +E
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD---IELGCSTPLMEASQEGHLE 549
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 550 LVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAG 591
Score = 96.3 bits (229), Expect = 1e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AA A H ++ R+LL +GA + + E +++ L +A G++D+ LL+ GAD
Sbjct: 338 GHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGAD 397
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 398 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 457
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 458 IERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGF 517
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E A L++ GA + E TPL A+Q+GH E+ LL G
Sbjct: 518 SEVADFLIKAGA--DIELGCS-TPLMEASQEGHLELVKYLLASG 558
Score = 78.2 bits (184), Expect = 3e-14
Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 216 GDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITP 275
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L A+ G L + LLL H A + G T L A + LL +GA+ +
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHN 335
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL AA +E A LL++GA N S + + L LA +GH +M LLE G
Sbjct: 336 ENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAG 395
Score = 67.7 bits (158), Expect = 4e-11
Identities = 52/158 (32%), Positives = 77/158 (48%), Gaps = 1/158 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA +E E TPL A+R G+ ++ LLL GA++
Sbjct: 439 ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANIN 498
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L A++ G+L++ LL
Sbjct: 499 AQTEETQETALTLACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
A GA G T L A + VA LL+ GAD
Sbjct: 556 ASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 593
Score = 66.5 bits (155), Expect = 9e-11
Identities = 59/228 (25%), Positives = 94/228 (41%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 137 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAE 196
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A D + L A + + L++ + T++G + L LA G ++A
Sbjct: 197 NSHNAGQVDTRS-LAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQ 255
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL A+ + LL AD + + G+T L A
Sbjct: 256 VLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAG 315
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LL GA ++ G TPL AA GH E+ +LL+ G G
Sbjct: 316 GFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAG 363
Score = 64.1 bits (149), Expect = 5e-10
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G ++A L++ GAD
Sbjct: 471 GYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGAD 530
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL A+++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 531 IELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Query: 367 LAHGAAPDQ 393
L GA D+
Sbjct: 588 LQAGADLDK 596
>BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein.
Length = 751
Score = 107 bits (256), Expect = 5e-23
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G +++A L++ GAD
Sbjct: 500 GYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD 559
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL AA++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 560 IELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 616
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ + A N HT L +A
Sbjct: 617 LQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGH 676
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L AA+ GHT + LL+
Sbjct: 677 LAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 718
Score = 105 bits (252), Expect = 2e-22
Identities = 72/224 (32%), Positives = 116/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A + D++++LL +GA++E TPL A G+V++A LLL++GA +
Sbjct: 334 GNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGI 393
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + ++ L+E A T + TAL A G+++VA LL
Sbjct: 394 NTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 453
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA + V G+TPL AAR+
Sbjct: 454 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHE 513
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G E+ L++ G
Sbjct: 514 EMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAG 557
Score = 105 bits (251), Expect = 2e-22
Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H +++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 402 ESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 461
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLL
Sbjct: 462 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 521
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL AA++ +E
Sbjct: 522 QGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD---IELGCSTPLMEAAQEGHLE 578
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 579 LVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAG 620
Score = 98.7 bits (235), Expect = 2e-20
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ A A H ++ R+LL NGA + + E +++ L +A G++++ LL+ GAD
Sbjct: 367 GHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGAD 426
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 427 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 486
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA+ ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 487 IERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGF 546
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A L++ GA + E TPL AAQ+GH E+ LL G
Sbjct: 547 LEVADFLIKAGA--DIELGCS-TPLMEAAQEGHLELVKYLLAAG 587
Score = 94.7 bits (225), Expect = 3e-19
Identities = 75/223 (33%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA++E E TPL A+R G+ ++ LLL GA++
Sbjct: 468 ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 527
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L AA+ G+L++ LL
Sbjct: 528 AQTEETQETALTLACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLL 584
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 585 AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVC 644
Query: 550 TAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T L+ GA N + T L LA GH + LLL G
Sbjct: 645 TVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 687
Score = 82.2 bits (194), Expect = 2e-15
Identities = 63/180 (35%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 245 GDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITP 304
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G++K+ LLLAH A + G T L A V LLE GA +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHN 364
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL A +E A LLE GA N S + + L LA +GH EM LLE G
Sbjct: 365 ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAG 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 64/228 (28%), Positives = 98/228 (42%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 166 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAE 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A +D+ + ++ + V LIE + + T++G + L LA G ++A
Sbjct: 226 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRS-VNEHTEEGESLLCLACSAGYYELAQ 284
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL AA + LL AD A + G+T L A
Sbjct: 285 VLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAG 344
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LLE GA ++ G TPL A GH E+ LLLE G G
Sbjct: 345 GYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAG 392
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA ++ L++ GA +E TPL A++ G++++ LL GA+V
Sbjct: 535 ETALTLACCGGFLEVADFLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVH 591
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G++ L++
Sbjct: 592 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLIS 651
Query: 373 HGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ N T L +A AV LL GAD K+G T L AA+
Sbjct: 652 KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTS 711
Query: 550 TAATLLEY 573
LL+Y
Sbjct: 712 VVCYLLDY 719
Score = 64.1 bits (149), Expect = 5e-10
Identities = 43/124 (34%), Positives = 63/124 (50%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G+V L+ G
Sbjct: 594 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 653
Query: 181 ADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V TA++ + L +A + V L+ H A T K G T L AAK G+ V
Sbjct: 654 ANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVV 713
Query: 358 NLLL 369
LL
Sbjct: 714 CYLL 717
Score = 46.0 bits (104), Expect = 1e-04
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A T L +A G++ + LLL HGAD
Sbjct: 630 GRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGAD 689
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
D L AAK + V L+++ L + T L
Sbjct: 690 PTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQL 734
>BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein.
Length = 830
Score = 107 bits (256), Expect = 5e-23
Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G +++A L++ GAD
Sbjct: 320 GYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD 379
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL AA++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 380 IELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 436
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA-KAVAKNGHTPLHIAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ + A N HT L +A
Sbjct: 437 LQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGH 496
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L AA+ GHT + LL+
Sbjct: 497 LAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 538
Score = 105 bits (251), Expect = 2e-22
Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H +++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 222 ESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 281
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLL
Sbjct: 282 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 341
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL AA++ +E
Sbjct: 342 QGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD---IELGCSTPLMEAAQEGHLE 398
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 399 LVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAG 440
Score = 101 bits (243), Expect = 2e-21
Identities = 77/227 (33%), Positives = 111/227 (48%), Gaps = 2/227 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQH 177
T GE+ + LA A + ++ ++LL A VE + + TPL A+ G+V I LLL H
Sbjct: 84 TEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAH 143
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
ADV A ++ L A DV L+E A + + G T L A G+++VA
Sbjct: 144 KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVA 203
Query: 358 NLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
LLL +GA + + + + L +A + LLE GAD + HT L A
Sbjct: 204 RLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACM 263
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A LL+ GA N + + +PL LAA GH E+ ALL+E G
Sbjct: 264 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERG 310
Score = 98.7 bits (235), Expect = 2e-20
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ A A H ++ R+LL NGA + + E +++ L +A G++++ LL+ GAD
Sbjct: 187 GHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGAD 246
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 247 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 306
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA+ ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 307 IERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGF 366
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A L++ GA + E TPL AAQ+GH E+ LL G
Sbjct: 367 LEVADFLIKAGA--DIELGCS-TPLMEAAQEGHLELVKYLLAAG 407
Score = 94.7 bits (225), Expect = 3e-19
Identities = 75/223 (33%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA++E E TPL A+R G+ ++ LLL GA++
Sbjct: 288 ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 347
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L AA+ G+L++ LL
Sbjct: 348 AQTEETQETALTLACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLL 404
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 405 AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVC 464
Query: 550 TAATLLEYGALTN-AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T L+ GA N + T L LA GH + LLL G
Sbjct: 465 TVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 507
Score = 82.2 bits (194), Expect = 2e-15
Identities = 63/180 (35%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 65 GDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITP 124
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G++K+ LLLAH A + G T L A V LLE GA +
Sbjct: 125 LMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHN 184
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL A +E A LLE GA N S + + L LA +GH EM LLE G
Sbjct: 185 ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAG 244
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA ++ L++ GA +E TPL A++ G++++ LL GA+V
Sbjct: 355 ETALTLACCGGFLEVADFLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVH 411
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G++ L++
Sbjct: 412 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLIS 471
Query: 373 HGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA ++ N T L +A AV LL GAD K+G T L AA+
Sbjct: 472 KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTS 531
Query: 550 TAATLLEY 573
LL+Y
Sbjct: 532 VVCYLLDY 539
Score = 72.1 bits (169), Expect = 2e-12
Identities = 46/129 (35%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T++G + L LA G ++A +LLA H D+ K +TPL AA + LL
Sbjct: 84 TEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAH 143
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
AD A + G+T L A ++ LLE GA ++ G TPL A GH E+
Sbjct: 144 KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVA 203
Query: 655 ALLLEGGPG 681
LLLE G G
Sbjct: 204 RLLLENGAG 212
Score = 64.1 bits (149), Expect = 5e-10
Identities = 43/124 (34%), Positives = 63/124 (50%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G+V L+ G
Sbjct: 414 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 473
Query: 181 ADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V TA++ + L +A + V L+ H A T K G T L AAK G+ V
Sbjct: 474 ANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVV 533
Query: 358 NLLL 369
LL
Sbjct: 534 CYLL 537
Score = 46.0 bits (104), Expect = 1e-04
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVE-AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA V A T L +A G++ + LLL HGAD
Sbjct: 450 GRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGAD 509
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
D L AAK + V L+++ L + T L
Sbjct: 510 PTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQL 554
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 106 bits (255), Expect = 7e-23
Identities = 62/220 (28%), Positives = 103/220 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T H AA D + L+ +G K +E T LH+A+ G++ + L+ G D+
Sbjct: 65 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 124
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ LH AA + D L+ + + A T+K + LH AA G+ V+ +L+
Sbjct: 125 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 184
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + G +PLH+A +++ A+ L+ +D AV TPLH+AA +
Sbjct: 185 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 244
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL G N + G T L +A + H + ++++
Sbjct: 245 IADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMIIK 284
Score = 90.6 bits (215), Expect = 5e-18
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN--GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
G T +H AA+ H ++ ++ + A++ + +T H A+ G +D L+ G
Sbjct: 30 GLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGC 89
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
D + LH+AA + + V L++ L +G TALH AA + L
Sbjct: 90 DHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQL 149
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL G+ + + ++ LH AA + V+ L+ G A V G +PLH+A R N
Sbjct: 150 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 209
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ + NA TPLHLAA+ ++ +LL G
Sbjct: 210 PALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 253
Score = 64.1 bits (149), Expect = 5e-10
Identities = 42/121 (34%), Positives = 61/121 (50%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-- 492
L L+A +G+L++ +L+ GA K+G+T LH AAQ V ++E D
Sbjct: 1 LLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDH 60
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
V K G T H AA Q++ L+ G N + K G T LHLAA +GH + L++
Sbjct: 61 VDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDI 120
Query: 673 G 675
G
Sbjct: 121 G 121
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/89 (30%), Positives = 48/89 (53%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G +P+HLA R N ++R+L+ + + V A +QTPLH+A+ DIA +LL G D
Sbjct: 196 QGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 255
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIE 273
+ L +A + ++ + +I+
Sbjct: 256 LNLRDEQGKTALAVAVRSNHVSLVDMIIK 284
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 106 bits (255), Expect = 7e-23
Identities = 62/220 (28%), Positives = 103/220 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T H AA D + L+ +G K +E T LH+A+ G++ + L+ G D+
Sbjct: 68 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 127
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ LH AA + D L+ + + A T+K + LH AA G+ V+ +L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + G +PLH+A +++ A+ L+ +D AV TPLH+AA +
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 247
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A LL G N + G T L +A + H + ++++
Sbjct: 248 IADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMIIK 287
Score = 90.6 bits (215), Expect = 5e-18
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN--GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
G T +H AA+ H ++ ++ + A++ + +T H A+ G +D L+ G
Sbjct: 33 GLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGC 92
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
D + LH+AA + + V L++ L +G TALH AA + L
Sbjct: 93 DHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQL 152
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL G+ + + ++ LH AA + V+ L+ G A V G +PLH+A R N
Sbjct: 153 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 212
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ + NA TPLHLAA+ ++ +LL G
Sbjct: 213 PALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 256
Score = 65.7 bits (153), Expect = 2e-10
Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA- 492
AL L+A +G+L++ +L+ GA K+G+T LH AAQ V ++E D
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 493 -VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
V K G T H AA Q++ L+ G N + K G T LHLAA +GH + L++
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Query: 670 GG 675
G
Sbjct: 123 IG 124
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/89 (30%), Positives = 48/89 (53%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G +P+HLA R N ++R+L+ + + V A +QTPLH+A+ DIA +LL G D
Sbjct: 199 QGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIE 273
+ L +A + ++ + +I+
Sbjct: 259 LNLRDEQGKTALAVAVRSNHVSLVDMIIK 287
>AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens
cDNA FLJ10421 fis, clone NT2RP1000202, weakly similar to
ANKYRIN. ).
Length = 445
Score = 106 bits (255), Expect = 7e-23
Identities = 76/231 (32%), Positives = 108/231 (46%), Gaps = 6/231 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G +HLAA H I++ILL GA A E TPL A G +D+ LLLQHG
Sbjct: 3 TFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHG 62
Query: 181 ADVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+V + + +N LH A+ Q N ++ L+ A G T L +AA+YG L+
Sbjct: 63 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 122
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK--NGHTPLHIAA 531
++L++ GA + + TPL IAAQ LL GAD + P+H AA
Sbjct: 123 SILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAA 182
Query: 532 RKNQMETAATLLEYGALTNAESKAGF---TPLHLAAQQGHTEMCALLLEGG 675
+ + L+ LTN G +P++ A GH + +LL G
Sbjct: 183 QMGHTKILDLLI---PLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRNG 230
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKA 102
+PV+ A H D + ILLRNG + +A+A
Sbjct: 209 SPVYSAVFGGHEDCLEILLRNGYSPDAQA 237
>BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 105 bits (253), Expect = 1e-22
Identities = 63/173 (36%), Positives = 88/173 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G++P HLAA T+ + ILL NGA + +K + T LH+A+ +LLQHGA+
Sbjct: 54 GQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANE 113
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ A++ +PLH AA L +H A L G T L +A+ G+ + + LL
Sbjct: 114 DAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLL 173
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
GA + KN + L +A + VA LL GADA AV GH LH A
Sbjct: 174 QRGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 89.8 bits (213), Expect = 9e-18
Identities = 59/183 (32%), Positives = 82/183 (44%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
Q+P H+A+ G + +LL +GAD+ + D LH+A L++H A
Sbjct: 55 QSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANED 114
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A + + LH AA G LL H A D +G TPL IA+ A+ + LL+
Sbjct: 115 AVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQ 174
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
+GA KN + L +A K E A LL +GA A G LH A HT+
Sbjct: 175 RGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYAL---HTQD 231
Query: 652 CAL 660
AL
Sbjct: 232 KAL 234
Score = 79.4 bits (187), Expect = 1e-14
Identities = 47/148 (31%), Positives = 75/148 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +HLA + +++LL++GA +A E ++PLH A+ G +LL H A +
Sbjct: 87 GSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFL 146
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D PL IA+ + + + L++ A + T K +AL LA + G+ +VA LLL
Sbjct: 147 DVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELLL 206
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
+HGA G LH A +A+
Sbjct: 207 SHGADAGAVDSTGHDALHYALHTQDKAL 234
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/198 (29%), Positives = 88/198 (44%), Gaps = 1/198 (0%)
Frame = +1
Query: 85 AVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAA 261
AVE R Q L R G+V +A L + A + ++ +P H+AA + +
Sbjct: 13 AVERWNRHDQKLLEAVHR-GDVGRVAALASRKSARPTKLDSNGQSPFHLAASKGLTECLT 71
Query: 262 ALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYD 441
L+ + A + + + G TALHLA + +LL HGA D +PLH AA
Sbjct: 72 ILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSG 131
Query: 442 QQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
+ L + A + +G TPL IA+ + LL+ GA N K + L
Sbjct: 132 CASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALI 191
Query: 622 LAAQQGHTEMCALLLEGG 675
LA ++G E+ LLL G
Sbjct: 192 LACEKGSAEVAELLLSHG 209
>BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 105 bits (253), Expect = 1e-22
Identities = 63/173 (36%), Positives = 88/173 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G++P HLAA T+ + ILL NGA + +K + T LH+A+ +LLQHGA+
Sbjct: 54 GQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANE 113
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ A++ +PLH AA L +H A L G T L +A+ G+ + + LL
Sbjct: 114 DAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLL 173
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
GA + KN + L +A + VA LL GADA AV GH LH A
Sbjct: 174 QRGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 89.8 bits (213), Expect = 9e-18
Identities = 59/183 (32%), Positives = 82/183 (44%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
Q+P H+A+ G + +LL +GAD+ + D LH+A L++H A
Sbjct: 55 QSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANED 114
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A + + LH AA G LL H A D +G TPL IA+ A+ + LL+
Sbjct: 115 AVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQ 174
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
+GA KN + L +A K E A LL +GA A G LH A HT+
Sbjct: 175 RGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYAL---HTQD 231
Query: 652 CAL 660
AL
Sbjct: 232 KAL 234
Score = 79.4 bits (187), Expect = 1e-14
Identities = 47/148 (31%), Positives = 75/148 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +HLA + +++LL++GA +A E ++PLH A+ G +LL H A +
Sbjct: 87 GSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFL 146
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D PL IA+ + + + L++ A + T K +AL LA + G+ +VA LLL
Sbjct: 147 DVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELLL 206
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
+HGA G LH A +A+
Sbjct: 207 SHGADAGAVDSTGHDALHYALHTQDKAL 234
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/198 (29%), Positives = 88/198 (44%), Gaps = 1/198 (0%)
Frame = +1
Query: 85 AVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAA 261
AVE R Q L R G+V +A L + A + ++ +P H+AA + +
Sbjct: 13 AVERWNRHDQKLLEAVHR-GDVGRVAALASRKSARPTKLDSNGQSPFHLAASKGLTECLT 71
Query: 262 ALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYD 441
L+ + A + + + G TALHLA + +LL HGA D +PLH AA
Sbjct: 72 ILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSG 131
Query: 442 QQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
+ L + A + +G TPL IA+ + LL+ GA N K + L
Sbjct: 132 CASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSALI 191
Query: 622 LAAQQGHTEMCALLLEGG 675
LA ++G E+ LLL G
Sbjct: 192 LACEKGSAEVAELLLSHG 209
>BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein.
Length = 1030
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 573 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 632
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 633 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 692
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 693 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 752
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 753 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 799
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 516 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 574
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 575 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 634
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 635 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 694
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 695 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 732
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 506 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 565
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 566 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 625
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 626 CERGCDVNLPDAHSDTPLHSAISAG 650
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 674 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 733
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 734 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 791
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 792 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 850
Query: 523 IAA 531
+AA
Sbjct: 851 LAA 853
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 484 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 541
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 542 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 601
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 602 INSTQSTALHVAVQRGFLEVVRALCERG 629
>AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 919
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 462 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 521
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 522 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 581
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 582 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 641
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 642 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 688
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 405 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 463
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 464 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 523
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 524 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 583
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 584 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 621
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 395 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 454
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 455 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 514
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 515 CERGCDVNLPDAHSDTPLHSAISAG 539
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 563 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 622
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 623 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 680
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 681 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 739
Query: 523 IAA 531
+AA
Sbjct: 740 LAA 742
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 373 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 430
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 431 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 490
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 491 INSTQSTALHVAVQRGFLEVVRALCERG 518
>AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 753
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 433 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 492
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 493 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 552
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 553 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 612
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 613 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 659
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 376 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 434
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 435 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 494
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 495 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 554
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 555 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 592
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 366 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 425
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 426 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 485
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 486 CERGCDVNLPDAHSDTPLHSAISAG 510
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 534 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 593
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 594 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 651
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 652 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 710
Query: 523 IAA 531
+AA
Sbjct: 711 LAA 713
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 344 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 401
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 402 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 461
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 462 INSTQSTALHVAVQRGFLEVVRALCERG 489
>AL691432-2|CAM12830.1| 948|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 948
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 491 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 550
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 551 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 610
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 611 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 670
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 671 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 717
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 434 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 492
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 493 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 552
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 553 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 612
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 613 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 650
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 424 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 483
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 484 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 543
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 544 CERGCDVNLPDAHSDTPLHSAISAG 568
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 592 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 651
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 652 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 709
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 710 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 768
Query: 523 IAA 531
+AA
Sbjct: 769 LAA 771
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 402 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 459
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 460 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 519
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 520 INSTQSTALHVAVQRGFLEVVRALCERG 547
>AL691432-1|CAM12831.1| 999|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 999
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 542 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 601
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 602 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 661
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 721
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 722 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 768
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 485 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 543
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 544 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 603
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 604 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 663
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 664 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 701
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 475 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 534
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 535 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 594
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 595 CERGCDVNLPDAHSDTPLHSAISAG 619
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 643 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 702
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 703 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 760
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 761 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 819
Query: 523 IAA 531
+AA
Sbjct: 820 LAA 822
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 453 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 510
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 511 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 570
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 571 INSTQSTALHVAVQRGFLEVVRALCERG 598
>AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens cDNA
FLJ25919 fis, clone CBR04994. ).
Length = 802
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 498 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 557
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 558 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 617
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 618 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 677
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 678 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 724
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 441 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 499
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 500 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 559
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 560 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 619
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 620 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 657
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 431 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 490
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 491 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 550
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 551 CERGCDVNLPDAHSDTPLHSAISAG 575
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 599 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 658
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 659 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 716
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 717 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 775
Query: 523 IAA 531
+AA
Sbjct: 776 LAA 778
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 409 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 466
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 467 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 526
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 527 INSTQSTALHVAVQRGFLEVVRALCERG 554
>AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens cDNA
FLJ39787 fis, clone SPLEN2002744, weakly similar to
ANKYRIN 2. ).
Length = 819
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 362 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 421
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 422 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 481
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 482 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 541
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 542 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 588
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 305 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 363
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 364 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 423
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 424 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 483
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 484 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 521
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 295 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 354
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 355 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 414
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 415 CERGCDVNLPDAHSDTPLHSAISAG 439
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 463 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 522
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 523 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 580
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 581 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 639
Query: 523 IAA 531
+AA
Sbjct: 640 LAA 642
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 273 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 330
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 331 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 390
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 391 INSTQSTALHVAVQRGFLEVVRALCERG 418
>AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens
cDNA FLJ38976 fis, clone NT2RI2004099, weakly similar to
ANKYRIN 2. ).
Length = 681
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 224 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 283
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 284 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 343
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 344 KILARARQLVDAKEEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 403
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 404 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 450
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 167 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 225
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 226 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 285
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 286 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 345
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 346 LARARQLVDAKEEDGFTALHLAALNNHREVAQILIREG 383
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 157 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 216
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 217 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 276
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 277 CERGCDVNLPDAHSDTPLHSAISAG 301
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 325 QGFTLLHHASLKGHALAVRKILARARQLVDAKEEDGFTALHLAALNNHREVAQILIREGR 384
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 385 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 442
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 443 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 501
Query: 523 IAA 531
+AA
Sbjct: 502 LAA 504
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 135 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 192
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 193 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 252
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 253 INSTQSTALHVAVQRGFLEVVRALCERG 280
>AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens
cDNA FLJ38595 fis, clone HEART2001773, weakly similar to
ANKYRIN 2. ).
Length = 681
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 224 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 283
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 284 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 343
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 344 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 403
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 404 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 450
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 167 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 225
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 226 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 285
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 286 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 345
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 346 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 383
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 157 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 216
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 217 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 276
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 277 CERGCDVNLPDAHSDTPLHSAISAG 301
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 325 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 384
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 385 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 442
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 443 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 501
Query: 523 IAA 531
+AA
Sbjct: 502 LAA 504
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 135 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 192
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 193 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 252
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 253 INSTQSTALHVAVQRGFLEVVRALCERG 280
>AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens
cDNA FLJ34291 fis, clone FEBRA2004620, weakly similar to
ANKYRIN 2. ).
Length = 645
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 188 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 247
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 248 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 307
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 308 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 367
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 368 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 414
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 131 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 189
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 190 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 249
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 250 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 309
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 310 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 347
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 121 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 180
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 181 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 240
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 241 CERGCDVNLPDAHSDTPLHSAISAG 265
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 289 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 348
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 349 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 406
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 407 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 465
Query: 523 IAA 531
+AA
Sbjct: 466 LAA 468
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 99 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 156
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 157 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 216
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 217 INSTQSTALHVAVQRGFLEVVRALCERG 244
>AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activating
protein protein.
Length = 999
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 542 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 601
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 602 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 661
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 721
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 722 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 768
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 485 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 543
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 544 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 603
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 604 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 663
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 664 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 701
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 475 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 534
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 535 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 594
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 595 CERGCDVNLPDAHSDTPLHSAISAG 619
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 643 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 702
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 703 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 760
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 761 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 819
Query: 523 IAA 531
+AA
Sbjct: 820 LAA 822
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 453 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 510
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 511 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 570
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 571 INSTQSTALHVAVQRGFLEVVRALCERG 598
>AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma protein.
Length = 1009
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 552 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 611
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 612 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 671
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 672 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 731
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 732 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 778
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 495 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 553
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 554 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 613
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 614 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 673
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 674 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 711
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 485 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 544
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 545 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 604
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 605 CERGCDVNLPDAHSDTPLHSAISAG 629
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 653 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 712
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 713 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 770
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 771 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 829
Query: 523 IAA 531
+AA
Sbjct: 830 LAA 832
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 463 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 520
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 521 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 580
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 581 INSTQSTALHVAVQRGFLEVVRALCERG 608
>AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein.
Length = 948
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 491 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 550
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 551 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 610
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 611 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 670
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 671 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 717
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 434 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 492
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 493 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 552
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 553 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 612
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 613 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 650
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 424 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 483
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 484 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 543
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 544 CERGCDVNLPDAHSDTPLHSAISAG 568
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 592 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 651
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 652 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 709
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 710 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 768
Query: 523 IAA 531
+AA
Sbjct: 769 LAA 771
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 402 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 459
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 460 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 519
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 520 INSTQSTALHVAVQRGFLEVVRALCERG 547
>AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha protein.
Length = 999
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 542 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 601
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 602 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 661
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 721
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 722 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 768
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 485 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 543
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 544 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 603
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 604 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 663
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 664 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 701
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 475 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 534
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 535 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 594
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 595 CERGCDVNLPDAHSDTPLHSAISAG 619
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 643 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 702
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 703 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 760
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 761 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 819
Query: 523 IAA 531
+AA
Sbjct: 820 LAA 822
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 453 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 510
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 511 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 570
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 571 INSTQSTALHVAVQRGFLEVVRALCERG 598
>AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein.
Length = 1013
Score = 105 bits (253), Expect = 1e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 556 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 615
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 616 NLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 675
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 676 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 735
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 736 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 782
Score = 81.0 bits (191), Expect = 4e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 499 ALGNAARALDLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 557
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 558 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 617
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 618 PDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 677
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 678 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 715
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 489 EHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 548
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 549 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 608
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 609 CERGCDVNLPDAHSDTPLHSAISAG 633
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 657 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 716
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 717 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 774
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 775 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 833
Query: 523 IAA 531
+AA
Sbjct: 834 LAA 836
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 467 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALDLLRRRPEQVDTKNQGR 524
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 525 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 584
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 585 INSTQSTALHVAVQRGFLEVVRALCERG 612
>BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein.
Length = 999
Score = 105 bits (252), Expect = 2e-22
Identities = 73/229 (31%), Positives = 113/229 (49%), Gaps = 5/229 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA N + R+LL G +A + T LH+A + G +++ L + G DV
Sbjct: 542 GNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDV 601
Query: 190 RAITADHYNPLH--IAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGN-LKVA 357
A PLH I+A + L E N +TAT +GFT LH A+ G+ L V
Sbjct: 602 NLPDAHSDTPLHSAISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 661
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAAR 534
+L D ++G T LH+AA + + VA L+ +G D + +PLH+A +
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQ 721
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+ + L++ G NAE + G T LH+A Q+ H ++ L+ +G G
Sbjct: 722 QAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQR-H-QLLPLVADGAGG 768
Score = 80.2 bits (189), Expect = 7e-15
Identities = 66/218 (30%), Positives = 94/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 34 ARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHY 213
A N + +L R V+ K + R T L +A+ LG V++ LLLQ A V +
Sbjct: 485 ALGNAARALGLLRRRPEQVDTKNQGR-TALQVAAYLGQVELIRLLLQARAGVDLPDDEGN 543
Query: 214 NPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH AA + + L+ A TALH+A + G L+V L G +
Sbjct: 544 TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNL 603
Query: 394 AGKNGMTPLH--IAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIAARK-NQMETAAT 561
+ TPLH I+A + L E D A G T LH A+ K + +
Sbjct: 604 PDAHSDTPLHSAISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKI 663
Query: 562 LLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L L +A+ + GFT LHLAA H E+ +L+ G
Sbjct: 664 LARARQLVDAKKEDGFTALHLAALNNHREVAQILIREG 701
Score = 66.9 bits (156), Expect = 7e-11
Identities = 45/145 (31%), Positives = 59/145 (40%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
+H L + N A L+ T +G TAL +AA G +++ LLL A
Sbjct: 475 EHPGRLVVEVALGNAARALGLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAG 534
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
D G T LH AA +Q LL G A A+ T LH+A ++ +E L
Sbjct: 535 VDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRAL 594
Query: 565 LEYGALTNAESKAGFTPLHLAAQQG 639
E G N TPLH A G
Sbjct: 595 CERGCDVNLPDAHSDTPLHSAISAG 619
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 8/183 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIR-ILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG- 180
+G T +H A+ H +R IL R V+AK + T LH+A+ + ++A +L++ G
Sbjct: 643 QGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR 702
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV +PLH+A +Q + + L++ + A ++G TALH+A + L
Sbjct: 703 CDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLP-- 760
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQ------AVATTLLEKGADAKAVAKNGHTPLH 522
L+A GA D ++ L + AVA L +GAD G +PL
Sbjct: 761 -LVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLD 819
Query: 523 IAA 531
+AA
Sbjct: 820 LAA 822
Score = 53.2 bits (122), Expect = 9e-07
Identities = 43/148 (29%), Positives = 61/148 (41%)
Frame = +1
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+++ ++ AL + A + G + +A GN A LL G
Sbjct: 453 ARENKSSLSVALDKLRAQKSDPEHPGRLVVEVAL--GNAARALGLLRRRPEQVDTKNQGR 510
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNA 591
T L +AA Q + LL+ A G+T LH AA NQ E LL G +A
Sbjct: 511 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA 570
Query: 592 ESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ T LH+A Q+G E+ L E G
Sbjct: 571 INSTQSTALHVAVQRGFLEVVRALCERG 598
>AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens
cDNA FLJ33801 fis, clone CTONG2000411. ).
Length = 1001
Score = 105 bits (252), Expect = 2e-22
Identities = 63/173 (36%), Positives = 87/173 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G++P HLAA T+ + ILL NGA + +K + T LH+A+ +LLQHGA+
Sbjct: 54 GQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANE 113
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ A++ +PLH AA L +H A L G T L +A+ G+ + + LL
Sbjct: 114 DAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLL 173
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
GA + KN L +A + VA LL GADA AV GH LH A
Sbjct: 174 QRGARVNVTDKNDKAALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 89.4 bits (212), Expect = 1e-17
Identities = 59/183 (32%), Positives = 81/183 (44%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
Q+P H+A+ G + +LL +GAD+ + D LH+A L++H A
Sbjct: 55 QSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANED 114
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A + + LH AA G LL H A D +G TPL IA+ A+ + LL+
Sbjct: 115 AVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQ 174
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
+GA KN L +A K E A LL +GA A G LH A HT+
Sbjct: 175 RGARVNVTDKNDKAALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYAL---HTQD 231
Query: 652 CAL 660
AL
Sbjct: 232 KAL 234
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/148 (31%), Positives = 74/148 (50%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +HLA + +++LL++GA +A E ++PLH A+ G +LL H A +
Sbjct: 87 GSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFL 146
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D PL IA+ + + + L++ A + T K AL LA + G+ +VA LLL
Sbjct: 147 DVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKAALILACEKGSAEVAELLL 206
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
+HGA G LH A +A+
Sbjct: 207 SHGADAGAVDSTGHDALHYALHTQDKAL 234
Score = 78.2 bits (184), Expect = 3e-14
Identities = 59/198 (29%), Positives = 87/198 (43%), Gaps = 1/198 (0%)
Frame = +1
Query: 85 AVEAKARERQTPLHIASRLGNVD-IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAA 261
AVE R Q L R G+V +A L + A + ++ +P H+AA + +
Sbjct: 13 AVERWNRHDQKLLEAVHR-GDVGRVAALASRKSARPTKLDSNGQSPFHLAASKGLTECLT 71
Query: 262 ALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYD 441
L+ + A + + + G TALHLA + +LL HGA D +PLH AA
Sbjct: 72 ILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSG 131
Query: 442 QQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
+ L + A + +G TPL IA+ + LL+ GA N K L
Sbjct: 132 CASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKAALI 191
Query: 622 LAAQQGHTEMCALLLEGG 675
LA ++G E+ LLL G
Sbjct: 192 LACEKGSAEVAELLLSHG 209
>AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined breast
cancer antigen NY-BR-16 protein.
Length = 1188
Score = 105 bits (252), Expect = 2e-22
Identities = 72/224 (32%), Positives = 116/224 (51%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A + D++++LL +GA++E TPL A G+V++A LLL++GA +
Sbjct: 334 GNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGI 393
Query: 190 RAITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L +A + + ++ L+E A T + TAL A G+++VA LL
Sbjct: 394 NTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 453
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA + + +PL +AA +A L+E+GA + V G+TPL AAR+
Sbjct: 454 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHE 513
Query: 547 ETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
E A LL GA NA++ + T L LA G E+ L++ G
Sbjct: 514 EMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAG 557
Score = 105 bits (251), Expect = 2e-22
Identities = 77/222 (34%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+ + LA H +++R LL GA E K E T L A G+V++A LLL GA V
Sbjct: 402 ESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 461
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+PL +AA + ++AA LIE A L +G+T L AA+ G+ ++ LLL
Sbjct: 462 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 521
Query: 373 HGAAPD-QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + Q + T L +A VA L++ GAD + TPL AA++ +E
Sbjct: 522 QGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD---IELGCSTPLMEAAQEGHLE 578
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
LL GA +A + G T L A + GHT++ +LL+ G
Sbjct: 579 LVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAG 620
Score = 98.7 bits (235), Expect = 2e-20
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARE-RQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ A A H ++ R+LL NGA + + E +++ L +A G++++ LL+ GAD
Sbjct: 367 GHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGAD 426
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T + + L A + +VA L++ A + + L LAA G++++A LL
Sbjct: 427 QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALL 486
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA-VAKNGHTPLHIAARKNQ 543
+ GA+ ++ G TPL AA+ + + LL +GA+ A + T L +A
Sbjct: 487 IERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGF 546
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+E A L++ GA + E TPL AAQ+GH E+ LL G
Sbjct: 547 LEVADFLIKAGA--DIELGCS-TPLMEAAQEGHLELVKYLLAAG 587
Score = 93.5 bits (222), Expect = 7e-19
Identities = 75/223 (33%), Positives = 108/223 (48%), Gaps = 2/223 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
E+P+ LAA H ++ +L+ GA++E E TPL A+R G+ ++ LLL GA++
Sbjct: 468 ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 527
Query: 193 AITAD-HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A T + L +A +VA LI+ A + T L AA+ G+L++ LL
Sbjct: 528 AQTEETQETALTLACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLL 584
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A GA G T L A + VA LL+ GAD + ++ G TPL AAR +
Sbjct: 585 AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVC 644
Query: 550 TAATLLEYGALTNAESKAGFTPLH-LAAQQGHTEMCALLLEGG 675
T L+ GA +E + T L LA GH + LLL G
Sbjct: 645 TVQFLISKGAECESEPQLIMTILSALACAGGHLAVVELLLAHG 687
Score = 93.1 bits (221), Expect = 9e-19
Identities = 71/222 (31%), Positives = 111/222 (50%), Gaps = 2/222 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQHGAD 186
G TP+ AAR H +++ +LL GA + A+ E Q T L +A G +++A L++ GAD
Sbjct: 500 GYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGAD 559
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + PL AA++ + ++ L+ A + ATT G TAL A + G+ VA++L
Sbjct: 560 IELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 616
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH-IAARKNQ 543
L GA + + G TPL AA+ L+ KGA+ ++ + T L +A
Sbjct: 617 LQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTILSALACAGGH 676
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ LL +GA K G T L A + GHT + LL+
Sbjct: 677 LAVVELLLAHGADPTHRLKDGSTMLIEAPKGGHTSVGCYLLD 718
Score = 82.2 bits (194), Expect = 2e-15
Identities = 63/180 (35%), Positives = 84/180 (46%), Gaps = 2/180 (1%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG-FTA 318
G+V+ LL G V T + + L +A +++A L+ +A + KG T
Sbjct: 245 GDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITP 304
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G++K+ LLLAH A + G T L A V LLE GA +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHN 364
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAES-KAGFTPLHLAAQQGHTEMCALLLEGG 675
+NGHTPL A +E A LLE GA N S + + L LA +GH EM LLE G
Sbjct: 365 ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAG 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 64/228 (28%), Positives = 98/228 (42%), Gaps = 1/228 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
TV ET L A I ++ +G A R+ ++ L A+ ++
Sbjct: 166 TVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAE 225
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ A +D+ + ++ + V LIE + + T++G + L LA G ++A
Sbjct: 226 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRS-VNEHTEEGESLLCLACSAGYYELAQ 284
Query: 361 LLLA-HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LLA H D+ K +TPL AA + LL AD A + G+T L A
Sbjct: 285 VLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAG 344
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
++ LLE GA ++ G TPL A GH E+ LLLE G G
Sbjct: 345 GYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAG 392
Score = 68.9 bits (161), Expect = 2e-11
Identities = 57/188 (30%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET + LA ++ L++ GA +E TPL A++ G++++ LL GA+V
Sbjct: 535 ETALTLACCGGFLEVADFLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVH 591
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A TA L A + + DVA L++ A L ++ G T L AA+ G++ L++
Sbjct: 592 ATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLIS 651
Query: 373 HGAAPDQAGKNGMTPLH-IAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
GA + + MT L +A AV LL GAD K+G T L A +
Sbjct: 652 KGAECESEPQLIMTILSALACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAPKGGHTS 711
Query: 550 TAATLLEY 573
LL+Y
Sbjct: 712 VGCYLLDY 719
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/124 (32%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G+T + A HTD+ +LL+ GA +E ++ +TPL A+R G+V L+ G
Sbjct: 594 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 653
Query: 181 ADVRAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
A+ + L A H V L+ H A T K G T L A K G+ V
Sbjct: 654 AECESEPQLIMTILSALACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAPKGGHTSVG 713
Query: 358 NLLL 369
LL
Sbjct: 714 CYLL 717
Score = 41.9 bits (94), Expect = 0.002
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLH-IASRLGNVDIAVLLLQHGAD 186
G TP+ AARA H ++ L+ GA E++ + T L +A G++ + LLL HGAD
Sbjct: 630 GRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTILSALACAGGHLAVVELLLAHGAD 689
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
D L A K + V L+++ L + T L
Sbjct: 690 PTHRLKDGSTMLIEAPKGGHTSVGCYLLDYPNNLLSAPPPDVTQL 734
Score = 35.1 bits (77), Expect = 0.27
Identities = 22/51 (43%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
Frame = +1
Query: 481 DAKAVAKNGH-TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAA 630
D A ++ H T L +A E TLLE GA K GFTPL LAA
Sbjct: 1074 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1124
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +1
Query: 313 TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
TAL LA G+ ++ LL GA+ + K G TPL +AA
Sbjct: 1085 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1124
Score = 31.5 bits (68), Expect = 3.3
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +1
Query: 157 AVLLLQHGADVRAIT-ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
A+L + D+ A T ++H L +A + ++ L+E A + KKGFT L LAA
Sbjct: 1065 AMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1124
Score = 31.5 bits (68), Expect = 3.3
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = +1
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
Q N T L +A + + TLLE+GA + K G TPL +AA
Sbjct: 1078 QTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAA 1124
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 104 bits (250), Expect = 3e-22
Identities = 69/230 (30%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA V+ T LHIA+ G+++ A +LLQHG
Sbjct: 199 TRNGFTALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHG 258
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 259 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 318
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 319 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 378
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 379 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 428
Score = 100 bits (239), Expect = 6e-21
Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GADV+ + LHIA
Sbjct: 185 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATI 244
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 245 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 304
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 305 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 364
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 365 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 392
Score = 93.5 bits (222), Expect = 7e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 161 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 220
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 221 LLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 280
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 281 EQVTRLLLKFG 291
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 199 TRNGFTALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHG 258
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 259 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 318
Query: 658 LLLEGG 675
LL+E G
Sbjct: 319 LLMEEG 324
Score = 30.3 bits (65), Expect = 7.5
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 166 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 225
Query: 676 PGTQ 687
Q
Sbjct: 226 ADVQ 229
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 218 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 278 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 327
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 84 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 143
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 144 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 203
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 204 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 263
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 264 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 119
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 120 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 179
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 180 EQVTRLLLKFG 190
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 658 LLLEGG 675
LL+E G
Sbjct: 218 LLMEEG 223
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 676 PGTQ 687
Q
Sbjct: 125 ADIQ 128
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 218 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 278 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 327
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 84 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 143
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 144 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 203
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 204 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 263
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 264 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 119
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 120 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 179
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 180 EQVTRLLLKFG 190
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 658 LLLEGG 675
LL+E G
Sbjct: 218 LLMEEG 223
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 676 PGTQ 687
Q
Sbjct: 125 ADIQ 128
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 218 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 278 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 327
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 84 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 143
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 144 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 203
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 204 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 263
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 264 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 119
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 120 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 179
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 180 EQVTRLLLKFG 190
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 658 LLLEGG 675
LL+E G
Sbjct: 218 LLMEEG 223
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 676 PGTQ 687
Q
Sbjct: 125 ADIQ 128
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 218 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 278 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 327
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 84 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 143
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 144 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 203
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 204 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 263
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 264 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 119
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 120 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 179
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 180 EQVTRLLLKFG 190
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 658 LLLEGG 675
LL+E G
Sbjct: 218 LLMEEG 223
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 676 PGTQ 687
Q
Sbjct: 125 ADIQ 128
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 218 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 278 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 327
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 84 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 143
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 144 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 203
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 204 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 263
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 264 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 119
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 120 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 179
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 180 EQVTRLLLKFG 190
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 658 LLLEGG 675
LL+E G
Sbjct: 218 LLMEEG 223
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 676 PGTQ 687
Q
Sbjct: 125 ADIQ 128
>AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat
containing protein protein.
Length = 1101
Score = 104 bits (249), Expect = 4e-22
Identities = 68/187 (36%), Positives = 88/187 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
GET + AA ++ R+LL GAAV R PL R G+ I LLL HGADV
Sbjct: 135 GETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADV 194
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PL +AA + + L+ A + K+G TAL A G+L V L+
Sbjct: 195 NMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLV 254
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GAA D A KNG TPL +AA Y V L++ GA + V +G PL A
Sbjct: 255 DNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCPNTS 314
Query: 550 TAATLLE 570
TLL+
Sbjct: 315 VVVTLLK 321
Score = 87.8 bits (208), Expect = 4e-17
Identities = 57/186 (30%), Positives = 87/186 (46%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
+T L A+ G +++ LLL+ GA V PL +Q + + L+ H A +
Sbjct: 136 ETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVN 195
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
K+G T L +AA G+L + LLA GA+ K G+T L A +V +L++
Sbjct: 196 MADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVD 255
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
GA KNG TPL +AA E L+++GA+ +G PL A +T +
Sbjct: 256 NGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCPNTSV 315
Query: 652 CALLLE 669
LL+
Sbjct: 316 VVTLLK 321
Score = 82.6 bits (195), Expect = 1e-15
Identities = 50/152 (32%), Positives = 73/152 (48%)
Frame = +1
Query: 220 LHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAG 399
L AA + +V L+E A + ++G L + G+ ++ +LLL HGA + A
Sbjct: 139 LTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD 198
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
K G TPL +AA LL +GA + K G T L A K + +L++ GA
Sbjct: 199 KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGA 258
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T+ K G TPL LAA G E+ L++ G
Sbjct: 259 ATDHADKNGRTPLDLAAFYGDAEVVQFLVDHG 290
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/156 (31%), Positives = 76/156 (48%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG P+ R H I+ +LL +GA V ++ +TPL +A+ G++ LL GA
Sbjct: 167 RGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGAS 226
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ + + L A + + V +L+++ A K G T L LAA YG+ +V L
Sbjct: 227 IALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 286
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
+ HGA + +GM PL A +V TLL+K
Sbjct: 287 VDHGAMIEHVDYSGMRPLDRAVGCPNTSVVVTLLKK 322
Score = 79.8 bits (188), Expect = 9e-15
Identities = 70/245 (28%), Positives = 101/245 (41%), Gaps = 17/245 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ----- 174
G TP+ AA A + I+ +L + A V+ + Q L A+ G++++ L+Q
Sbjct: 19 GLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTM 78
Query: 175 HGADVRAITADH--YNPLHIAAKQHNHDVAAALIE---------HNAPLTATTKK-GFTA 318
G H L AA ++ + L++ A + + G TA
Sbjct: 79 AGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETA 138
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
L AA G L+V LLL GAA Q + G PL + + LL GAD
Sbjct: 139 LTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD 198
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
K G TPL +AA + + T LL GA K G T L A +GH + L++ G
Sbjct: 199 KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGA 258
Query: 679 GTQFA 693
T A
Sbjct: 259 ATDHA 263
Score = 62.5 bits (145), Expect = 2e-09
Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 17/224 (7%)
Frame = +1
Query: 55 IIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAA 234
++ +LL GA V+A + TPL A+ G + I VLL + A V + + L AA
Sbjct: 1 MVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAA 60
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGF-------TALHLAAKYGNLKVANLLLAHGAAPDQ 393
+ + +V LI+ + + + F AL AA G ++ + LL ++
Sbjct: 61 LRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEE 120
Query: 394 AGKN----------GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
+ G T L AA + V LLE+GA + G PL R+
Sbjct: 121 EVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGH 180
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ LL +GA N K G TPL +AA +GH LL G
Sbjct: 181 WQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQG 224
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 218 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 277
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 278 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 327
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 84 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 143
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 144 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 203
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 204 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 263
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 264 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 291
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 119
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 120 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 179
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 180 EQVTRLLLKFG 190
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 98 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 157
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 158 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 217
Query: 658 LLLEGG 675
LL+E G
Sbjct: 218 LLMEEG 223
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 65 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 676 PGTQ 687
Q
Sbjct: 125 ADIQ 128
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 104 bits (249), Expect = 4e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 204 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 263
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 264 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 323
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 324 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLA 383
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 384 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 433
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 190 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 249
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 250 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 309
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 310 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQP 369
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 370 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 397
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 166 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 225
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 226 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 285
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 286 EQVTRLLLKFG 296
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 204 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 263
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 264 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 323
Query: 658 LLLEGG 675
LL+E G
Sbjct: 324 LLMEEG 329
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 171 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 230
Query: 676 PGTQ 687
Q
Sbjct: 231 ADIQ 234
>BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protein 2
protein.
Length = 1202
Score = 103 bits (248), Expect = 5e-22
Identities = 74/216 (34%), Positives = 104/216 (48%), Gaps = 8/216 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +H AA ++I +LL A V+ K PLH A+ G ++ LLL+ A V
Sbjct: 49 GFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAV 108
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + D PLH+AA+ +++V+ L++H + K T L LA ++G LKVA LLL
Sbjct: 109 NAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLL 168
Query: 370 -AH-------GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+H G A D N TPLH+AA+ + V LL G + K G T LH
Sbjct: 169 NSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHE 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
AA + E LLE G N + T L + Q
Sbjct: 228 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQ 263
Score = 102 bits (244), Expect = 2e-21
Identities = 69/193 (35%), Positives = 98/193 (50%), Gaps = 8/193 (4%)
Frame = +1
Query: 121 LHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
LH A+ G++++ LLL+ A V ++ PLH AA Q + L+ +A + A +
Sbjct: 53 LHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAAS 112
Query: 301 KKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE--- 471
G LHLAA+YG+ +V+ +LL H + P K TPL +A ++ + VA LL
Sbjct: 113 LDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHL 172
Query: 472 -----KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
+G N TPLH+AA+ E LL G N ++K G T LH AA
Sbjct: 173 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHEAALY 231
Query: 637 GHTEMCALLLEGG 675
G TE+ LLLEGG
Sbjct: 232 GKTEVVRLLLEGG 244
Score = 86.2 bits (204), Expect = 1e-16
Identities = 60/166 (36%), Positives = 82/166 (49%), Gaps = 8/166 (4%)
Frame = +1
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
AD ++ LH AA + ++ A L+E A + G LH AA G L+ LLL A
Sbjct: 47 ADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASA 106
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
A + A +G PLH+AAQY V+ LL+ ++ V K TPL +A +++ A
Sbjct: 107 AVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQL 166
Query: 562 LLEYG---ALTNAESKAG-----FTPLHLAAQQGHTEMCALLLEGG 675
LL AL E+K TPLHLAA+ GH E+ LL G
Sbjct: 167 LLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAG 212
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+ P+HLAA+ H ++ +LL++ + + ++TPL +A G + +A LLL V
Sbjct: 115 GQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCV 174
Query: 190 RAITAD--------HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
+ + + PLH+AAK + +V L+ + TK G TALH AA YG
Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHEAALYGK 233
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
+V LLL G + T L I Q+ + + + +A + K
Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILK 285
Score = 40.7 bits (91), Expect = 0.005
Identities = 24/64 (37%), Positives = 29/64 (45%)
Frame = +1
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+G + LH AA +E A LLE A + + G PLH AA QG E LLL
Sbjct: 48 DGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAA 107
Query: 682 TQFA 693
A
Sbjct: 108 VNAA 111
>AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protein 2
protein.
Length = 1202
Score = 103 bits (248), Expect = 5e-22
Identities = 74/216 (34%), Positives = 104/216 (48%), Gaps = 8/216 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +H AA ++I +LL A V+ K PLH A+ G ++ LLL+ A V
Sbjct: 49 GFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAV 108
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A + D PLH+AA+ +++V+ L++H + K T L LA ++G LKVA LLL
Sbjct: 109 NAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLL 168
Query: 370 -AH-------GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+H G A D N TPLH+AA+ + V LL G + K G T LH
Sbjct: 169 NSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHE 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
AA + E LLE G N + T L + Q
Sbjct: 228 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQ 263
Score = 102 bits (244), Expect = 2e-21
Identities = 69/193 (35%), Positives = 98/193 (50%), Gaps = 8/193 (4%)
Frame = +1
Query: 121 LHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT 300
LH A+ G++++ LLL+ A V ++ PLH AA Q + L+ +A + A +
Sbjct: 53 LHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAAS 112
Query: 301 KKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE--- 471
G LHLAA+YG+ +V+ +LL H + P K TPL +A ++ + VA LL
Sbjct: 113 LDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHL 172
Query: 472 -----KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
+G N TPLH+AA+ E LL G N ++K G T LH AA
Sbjct: 173 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHEAALY 231
Query: 637 GHTEMCALLLEGG 675
G TE+ LLLEGG
Sbjct: 232 GKTEVVRLLLEGG 244
Score = 86.2 bits (204), Expect = 1e-16
Identities = 60/166 (36%), Positives = 82/166 (49%), Gaps = 8/166 (4%)
Frame = +1
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
AD ++ LH AA + ++ A L+E A + G LH AA G L+ LLL A
Sbjct: 47 ADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASA 106
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
A + A +G PLH+AAQY V+ LL+ ++ V K TPL +A +++ A
Sbjct: 107 AVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQL 166
Query: 562 LLEYG---ALTNAESKAG-----FTPLHLAAQQGHTEMCALLLEGG 675
LL AL E+K TPLHLAA+ GH E+ LL G
Sbjct: 167 LLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAG 212
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+ P+HLAA+ H ++ +LL++ + + ++TPL +A G + +A LLL V
Sbjct: 115 GQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCV 174
Query: 190 RAITAD--------HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
+ + + PLH+AAK + +V L+ + TK G TALH AA YG
Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG-TALHEAALYGK 233
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
+V LLL G + T L I Q+ + + + +A + K
Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILK 285
Score = 40.7 bits (91), Expect = 0.005
Identities = 24/64 (37%), Positives = 29/64 (45%)
Frame = +1
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPG 681
+G + LH AA +E A LLE A + + G PLH AA QG E LLL
Sbjct: 48 DGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAA 107
Query: 682 TQFA 693
A
Sbjct: 108 VNAA 111
>AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein.
Length = 1644
Score = 103 bits (248), Expect = 5e-22
Identities = 71/198 (35%), Positives = 94/198 (47%), Gaps = 1/198 (0%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T+ GET + AA ++ +LL +GAAV R PL A+R G+ I LLL+ G
Sbjct: 859 TLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERG 918
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
DV PL +AA + + L+ A L++ K+G +AL A G+ V
Sbjct: 919 CDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQ 978
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ GAA DQ KNG TPL +AA Y L+EKGA + V +G PL A
Sbjct: 979 YLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCR 1038
Query: 541 QMETAATLLEYGA-LTNA 591
LL GA L NA
Sbjct: 1039 NTSVVVALLRKGAKLGNA 1056
Score = 99.1 bits (236), Expect = 1e-20
Identities = 70/220 (31%), Positives = 101/220 (45%), Gaps = 5/220 (2%)
Frame = +1
Query: 31 AARANHTDIIRILL--RNGAAVEAKARER---QTPLHIASRLGNVDIAVLLLQHGADVRA 195
AA H+ +++ LL VE + +T L A+ G +++ LLL HGA V
Sbjct: 831 AASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSR 890
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
PL AA+Q + + L+E + + K+G T L +AA G+L LL+
Sbjct: 891 TNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSK 950
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
GAA K G++ L A +AV L+E+GA KNG TPL +AA ET
Sbjct: 951 GAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETV 1010
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+E GA+ +G PL A +T + LL G
Sbjct: 1011 LYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKG 1050
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Frame = +1
Query: 343 NLKVANLLLAHGAAPDQAGK--NGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
N+KV+ LL+ GA + + N L + + + V T LLE GA ++NG T
Sbjct: 695 NVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTA 754
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL--EGGPG 681
L AA M+ L + G + K G L +A +GH ++ LL E PG
Sbjct: 755 LCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPG 811
Score = 35.9 bits (79), Expect = 0.15
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Frame = +1
Query: 340 GNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
G+ +V LLL GA D +NGMT L AA + L +KG + K G L
Sbjct: 729 GHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCAL 788
Query: 520 -HIAAR 534
H A R
Sbjct: 789 VHSALR 794
>BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein
protein.
Length = 714
Score = 103 bits (247), Expect = 7e-22
Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 7/230 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G T +HLA ++ ++I LL +GA ++ T LHIA+ G+++ A +LLQHG
Sbjct: 216 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 275
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
A+V A + PLHIAA + V L++ A + + + G LHLA+ G L +A
Sbjct: 276 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 335
Query: 361 LLLAHGAAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAVAKN--GHTPLHIA 528
LL+ G+ D ++ PLH +++ + LL+ + + N G TPLH+A
Sbjct: 336 LLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEVQPHVVNIYGDTPLHLA 395
Query: 529 ARKNQMETAATLLEYGALTNAESKAGF--TPLHLAAQQGHT-EMCALLLE 669
+ E A +++ + + F T H A G + ++ LL+
Sbjct: 396 CYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLD 445
Score = 101 bits (241), Expect = 4e-21
Identities = 58/170 (34%), Positives = 87/170 (51%), Gaps = 2/170 (1%)
Frame = +1
Query: 166 LLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN 345
L+ G +T + + LH+A + N ++ +L+ A + G TALH+A G+
Sbjct: 205 LMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGH 264
Query: 346 LKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
L+ A++LL HGA + TPLHIAA Y + V LL+ GAD + G PLH+
Sbjct: 265 LEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHL 324
Query: 526 AARKNQMETAATLLEYG--ALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ K + A L+E G A NA+ PLH ++ GH +M LL+
Sbjct: 325 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQ 374
Score = 99 bits (238), Expect = 8e-21
Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
IR L+ G R T LH+A N ++ LL GAD++ + LHIA
Sbjct: 202 IRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATI 261
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + A L++H A + FT LH+AA YG+ +V LLL GA + +G+ G P
Sbjct: 262 AGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRP 321
Query: 418 LHIAAQYDQQAVATTLLEKG--ADAKAVAKNGHTPLHIAARKNQMETAATLL--EYGALT 585
LH+A+ +A L+E+G AD A H PLH +R + LL +
Sbjct: 322 LHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEVQP 381
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + G TPLHLA G E+ +++
Sbjct: 382 HVVNIYGDTPLHLACYNGKFEVAKEIIQ 409
Score = 93.1 bits (221), Expect = 9e-19
Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Frame = +1
Query: 286 LTATTKKGFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
L T+ G + LHL G K L+ G P + +NG T LH+A D + T+
Sbjct: 178 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITS 237
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL GAD + V G T LHIA +E A LL++GA N + FTPLH+AA GH
Sbjct: 238 LLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGH 297
Query: 643 TEMCALLLEGG 675
++ LLL+ G
Sbjct: 298 EQVTRLLLKFG 308
Score = 87.4 bits (207), Expect = 5e-17
Identities = 50/126 (39%), Positives = 64/126 (50%)
Frame = +1
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T+ GFTALHLA N ++ LL GA Q G G+T LHIA A LL+ G
Sbjct: 216 TRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHG 275
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCA 657
A+ TPLHIAA + LL++GA N + G PLHLA+ +G +
Sbjct: 276 ANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK 335
Query: 658 LLLEGG 675
LL+E G
Sbjct: 336 LLMEEG 341
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 499 KNGHTPLHIAARKNQMET-AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+NG + LH+ ++ TL+ G + ++ GFT LHLA + + E+ LL G
Sbjct: 183 ENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 242
Query: 676 PGTQ 687
Q
Sbjct: 243 ADIQ 246
>BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein.
Length = 1672
Score = 102 bits (244), Expect = 2e-21
Identities = 66/213 (30%), Positives = 103/213 (48%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A++ H I+ LL+ G +E + T L A G D+ LLL HGA+
Sbjct: 36 ASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYS 95
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
P+ AA + + D+ L+++ A + + K G T L AA+ G+L+ LLA GA D
Sbjct: 96 VYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVD 155
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
Q G N MT L +A + +L++ + K+G+T L IA+++ E LL+
Sbjct: 156 QEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLD 215
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
G N ++G T L A + GH E+ LL+
Sbjct: 216 AGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQ 248
Score = 95.5 bits (227), Expect = 2e-19
Identities = 61/219 (27%), Positives = 103/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AAR H + ++ LL GA V+ + T L +A + G +L+ +V
Sbjct: 128 GTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNV 187
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D L IA+K+ + ++ L++ + + G T L A + G++++ LL
Sbjct: 188 NLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALL 247
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A D G++ T L+ A + + +L+ D + K+G TPL A + +E
Sbjct: 248 QKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIE 307
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL+ GA +A K G TPLH+A + ++ LLL
Sbjct: 308 VVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLL 346
Score = 94.3 bits (224), Expect = 4e-19
Identities = 67/219 (30%), Positives = 103/219 (47%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+ AA H DI+ +LL+NGA V + TPL A+R G+++ LL GADV
Sbjct: 98 PIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQE 157
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
A+ L +A K +++ N + T K G TAL +A+K G+ ++ LL G
Sbjct: 158 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 217
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAA 558
+ ++G T L A + + LL+K AD ++ T L+ A K
Sbjct: 218 TYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVR 277
Query: 559 TLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+L+ T +K G TPL A + + E+ LLL+ G
Sbjct: 278 DILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKG 316
Score = 89.0 bits (211), Expect = 2e-17
Identities = 63/216 (29%), Positives = 101/216 (46%)
Frame = +1
Query: 28 LAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
+AA + +I++ L++NGA + + T L AS+ G+V I LL+ G ++
Sbjct: 2 IAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMG 61
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
+ L A + DV L+ H A + T + AA G+ + +LLL +GA
Sbjct: 62 GWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKV 121
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+ + K G TPL AA+ LL GAD N T L +A + ++ +L
Sbjct: 122 NCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEIL 181
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ N K G T L +A+++GHTE+ LL+ G
Sbjct: 182 KRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 217
Score = 86.6 bits (205), Expect = 8e-17
Identities = 58/184 (31%), Positives = 87/184 (47%)
Frame = +1
Query: 127 IASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK 306
IA+ GN++I L+++GA+ D++ L A+K+ + + L++ L
Sbjct: 2 IAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMG 61
Query: 307 GFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADA 486
G+TAL A G V LLL+HGA P G + P+ AA + LL+ GA
Sbjct: 62 GWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKV 121
Query: 487 KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
K G TPL AARK +E LL GA + E T L +A + G+T+ +L
Sbjct: 122 NCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEIL 181
Query: 667 EGGP 678
+ P
Sbjct: 182 KRNP 185
Score = 84.2 bits (199), Expect = 4e-16
Identities = 59/175 (33%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A++ HT+I++ LL G V R T L A R G+V+I LLQ AD+
Sbjct: 194 GNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADI 253
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D+ L+ A ++ N + +++ N TK G T L A K N++V LLL
Sbjct: 254 DIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLL 313
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV---AKNGHTPLHI 525
GA K G TPLHIA + + +A LL D + + K G TP +I
Sbjct: 314 DKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNI 368
Score = 75.4 bits (177), Expect = 2e-13
Identities = 60/226 (26%), Positives = 97/226 (42%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A TD++ +LL +GA P+ A+ G+ DI LLLQ+GA V
Sbjct: 62 GWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKV 121
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PL AA++ + + L+ A + TAL +A K G + +L
Sbjct: 122 NCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEIL 181
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ K+G T L IA++ + LL+ G ++G T L A R +E
Sbjct: 182 KRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVE 241
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A + + T L+ A ++G+ M +L+ P T+
Sbjct: 242 IVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTE 287
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/66 (37%), Positives = 39/66 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T GETP+ A + + +++ +LL GA V A ++ TPLHIA R + +A LLL++
Sbjct: 290 TKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNP 349
Query: 181 ADVRAI 198
D R +
Sbjct: 350 KDGRLL 355
>AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein.
Length = 1777
Score = 102 bits (244), Expect = 2e-21
Identities = 66/213 (30%), Positives = 103/213 (48%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A++ H I+ LL+ G +E + T L A G D+ LLL HGA+
Sbjct: 84 ASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYS 143
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
P+ AA + + D+ L+++ A + + K G T L AA+ G+L+ LLA GA D
Sbjct: 144 VYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVD 203
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
Q G N MT L +A + +L++ + K+G+T L IA+++ E LL+
Sbjct: 204 QEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLD 263
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
G N ++G T L A + GH E+ LL+
Sbjct: 264 AGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQ 296
Score = 96.7 bits (230), Expect = 8e-20
Identities = 66/222 (29%), Positives = 106/222 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+ +AA + +I++ L++NGA + + T L AS+ G+V I LL+ G ++
Sbjct: 44 GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNL 103
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ L A + DV L+ H A + T + AA G+ + +LLL
Sbjct: 104 EHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLL 163
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+GA + + K G TPL AA+ LL GAD N T L +A + +
Sbjct: 164 QNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQ 223
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ +L+ N K G T L +A+++GHTE+ LL+ G
Sbjct: 224 SVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 265
Score = 95.9 bits (228), Expect = 1e-19
Identities = 65/207 (31%), Positives = 98/207 (47%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
++ LL V+ + QTPL IA+ GN++I L+++GA+ D++ L A+K
Sbjct: 27 LKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASK 86
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTP 417
+ + + L++ L G+TAL A G V LLL+HGA P G + P
Sbjct: 87 EGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYP 146
Query: 418 LHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAES 597
+ AA + LL+ GA K G TPL AARK +E LL GA + E
Sbjct: 147 IIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEG 206
Query: 598 KAGFTPLHLAAQQGHTEMCALLLEGGP 678
T L +A + G+T+ +L+ P
Sbjct: 207 ANSMTALIVAVKGGYTQSVKEILKRNP 233
Score = 95.5 bits (227), Expect = 2e-19
Identities = 61/219 (27%), Positives = 103/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AAR H + ++ LL GA V+ + T L +A + G +L+ +V
Sbjct: 176 GTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNV 235
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D L IA+K+ + ++ L++ + + G T L A + G++++ LL
Sbjct: 236 NLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALL 295
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A D G++ T L+ A + + +L+ D + K+G TPL A + +E
Sbjct: 296 QKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIE 355
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL+ GA +A K G TPLH+A + ++ LLL
Sbjct: 356 VVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLL 394
Score = 94.3 bits (224), Expect = 4e-19
Identities = 67/219 (30%), Positives = 103/219 (47%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+ AA H DI+ +LL+NGA V + TPL A+R G+++ LL GADV
Sbjct: 146 PIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQE 205
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
A+ L +A K +++ N + T K G TAL +A+K G+ ++ LL G
Sbjct: 206 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 265
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAA 558
+ ++G T L A + + LL+K AD ++ T L+ A K
Sbjct: 266 TYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVR 325
Query: 559 TLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+L+ T +K G TPL A + + E+ LLL+ G
Sbjct: 326 DILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKG 364
Score = 84.2 bits (199), Expect = 4e-16
Identities = 59/175 (33%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A++ HT+I++ LL G V R T L A R G+V+I LLQ AD+
Sbjct: 242 GNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADI 301
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D+ L+ A ++ N + +++ N TK G T L A K N++V LLL
Sbjct: 302 DIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLL 361
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV---AKNGHTPLHI 525
GA K G TPLHIA + + +A LL D + + K G TP +I
Sbjct: 362 DKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNI 416
Score = 75.4 bits (177), Expect = 2e-13
Identities = 60/226 (26%), Positives = 97/226 (42%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + A TD++ +LL +GA P+ A+ G+ DI LLLQ+GA V
Sbjct: 110 GWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKV 169
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
PL AA++ + + L+ A + TAL +A K G + +L
Sbjct: 170 NCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEIL 229
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
+ K+G T L IA++ + LL+ G ++G T L A R +E
Sbjct: 230 KRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVE 289
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
LL+ A + + T L+ A ++G+ M +L+ P T+
Sbjct: 290 IVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTE 335
Score = 70.5 bits (165), Expect = 6e-12
Identities = 54/177 (30%), Positives = 75/177 (42%)
Frame = +1
Query: 145 NVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALH 324
N+ LL+ DV PL IAA+Q N ++ LI++ A +TAL
Sbjct: 23 NIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALI 82
Query: 325 LAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKN 504
A+K G++ + LL G + G T L A + V LL GA+
Sbjct: 83 SASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLY 142
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
P+ AA + + LL+ GA N K G TPL AA++GH E LL G
Sbjct: 143 SVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMG 199
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/147 (26%), Positives = 67/147 (45%)
Frame = +1
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
++ N AL+E + + G T L +AA+ GNL++ L+ +GA + + T
Sbjct: 20 EEENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWT 79
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
L A++ + LL+ G + + G T L A K + + LL +GA +
Sbjct: 80 ALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVT 139
Query: 595 SKAGFTPLHLAAQQGHTEMCALLLEGG 675
P+ AA +GH ++ LLL+ G
Sbjct: 140 GLYSVYPIIWAAGRGHADIVHLLLQNG 166
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/66 (37%), Positives = 39/66 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T GETP+ A + + +++ +LL GA V A ++ TPLHIA R + +A LLL++
Sbjct: 338 TKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNP 397
Query: 181 ADVRAI 198
D R +
Sbjct: 398 KDGRLL 403
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 457 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 516
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 636
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 637 AVNYHGDTPLHIAARESYHDCVLLFLSRG 665
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 657
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 658 VLLFLSRGANPELRNKEGDTAWDLTPER 685
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 570
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 571 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 630
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 631 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 690
Query: 553 AATL 564
A L
Sbjct: 691 ALQL 694
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 576 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 642 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 701
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 702 VGNRAIRTE 710
>BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 922
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 378 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 437
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 438 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 497
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 498 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 557
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 558 AVNYHGDTPLHIAARESYHDCVLLFLSRG 586
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 399 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 458
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 459 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 518
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 519 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 578
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 579 VLLFLSRGANPELRNKEGDTAWDLTPER 606
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 432 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 491
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 492 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 551
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 552 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 611
Query: 553 AATL 564
A L
Sbjct: 612 ALQL 615
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 497 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 556
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 557 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 602
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 563 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 622
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 623 VGNRAIRTE 631
>BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 888
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 344 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 403
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 404 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 463
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 464 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 523
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 524 AVNYHGDTPLHIAARESYHDCVLLFLSRG 552
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 365 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 424
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 425 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 484
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 485 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 544
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 545 VLLFLSRGANPELRNKEGDTAWDLTPER 572
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 398 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 457
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 458 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 517
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 518 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 577
Query: 553 AATL 564
A L
Sbjct: 578 ALQL 581
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 463 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 522
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 523 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 568
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 529 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 588
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 589 VGNRAIRTE 597
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 101 bits (243), Expect = 2e-21
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +1
Query: 55 IIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAA 234
+ +L + GA+ E +T H+A+ G+V+ +++ HG DV A ++ LH+AA
Sbjct: 35 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 94
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
K +H+ L++ P + G TALH AA G L+ +L H + + +G
Sbjct: 95 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 154
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL +A Q + LL+ GAD + K+G T L +A L++ GA N
Sbjct: 155 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLV 214
Query: 595 SKAGFTPLHLAAQQGHTEMCALLL 666
G+ LH + + + +LLL
Sbjct: 215 DSLGYNALHYSKLSENAGIQSLLL 238
Score = 89.4 bits (212), Expect = 1e-17
Identities = 50/171 (29%), Positives = 81/171 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T HLAA H + +R+++ +G V A+ + LH+A++ + + LLQ
Sbjct: 53 GKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPA 112
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ + LH AA Q L EH +P+ G L LA + G+ ++ + LL
Sbjct: 113 ESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 172
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
HGA + K+G T L +A + L++KGAD V G+ LH
Sbjct: 173 DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 223
Score = 81.8 bits (193), Expect = 2e-15
Identities = 46/141 (32%), Positives = 71/141 (50%)
Frame = +1
Query: 253 VAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
VA+ L + A T +G TA HLAA G+++ +++ HG G + LH+AA
Sbjct: 35 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 94
Query: 433 QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
+ LL+ A++V +G T LH AA + ++ L E+ + N + G
Sbjct: 95 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 154
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PL LA Q GH+E+C LL+ G
Sbjct: 155 PLLLAVQNGHSEICHFLLDHG 175
Score = 74.1 bits (174), Expect = 5e-13
Identities = 49/174 (28%), Positives = 78/174 (44%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+A LL + GA ++ H+AA + + + +I H +TA G +ALHLAA
Sbjct: 35 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 94
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT 513
K + + LL + +G T LH AA L E + +G+
Sbjct: 95 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 154
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
PL +A + E LL++GA N+ +K+G T L LA + G + L++ G
Sbjct: 155 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKG 208
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLAA+ +H + IR LL++ E+ +T LH A+ G + +L +H + +
Sbjct: 86 GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPI 145
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PL +A + + ++ L++H A + + K G TAL LA + G+ L+
Sbjct: 146 NLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALI 205
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK---GADAKAVAK 501
GA + G LH + + + + LL K AD K K
Sbjct: 206 KKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTK 252
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/107 (31%), Positives = 49/107 (45%)
Frame = +1
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
KVA+LL GA+ + G T H+AA ++ G D A GH+ LH+A
Sbjct: 34 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 93
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ + E LL+ + +G T LH AA QG + +L E
Sbjct: 94 AKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCE 140
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
KN L D + VA+ L +KGA A G T H+AA K +E ++ +G
Sbjct: 18 KNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGV 77
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ G + LHLAA+ H E LL+
Sbjct: 78 DVTAQDTTGHSALHLAAKNSHHECIRKLLQ 107
Score = 30.3 bits (65), Expect = 7.5
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Frame = +1
Query: 526 AARKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A E A+LL + GA G T HLAA +GH E +++ G
Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76
>BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein.
Length = 1198
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 654 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 713
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 714 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 773
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 774 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 833
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 834 AVNYHGDTPLHIAARESYHDCVLLFLSRG 862
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 675 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 734
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 735 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 794
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 795 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 854
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 855 VLLFLSRGANPELRNKEGDTAWDLTPER 882
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 708 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 767
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 768 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 827
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 828 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 887
Query: 553 AATL 564
A L
Sbjct: 888 ALQL 891
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 773 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 832
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 833 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 878
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 839 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 898
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 899 VGNRAIRTE 907
>BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein.
Length = 1001
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 457 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 516
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 636
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 637 AVNYHGDTPLHIAARESYHDCVLLFLSRG 665
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 657
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 658 VLLFLSRGANPELRNKEGDTAWDLTPER 685
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 570
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 571 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 630
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 631 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 690
Query: 553 AATL 564
A L
Sbjct: 691 ALQL 694
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 576 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 642 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 701
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 702 VGNRAIRTE 710
>BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein.
Length = 1209
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 665 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 724
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 725 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 784
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 785 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 844
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 845 AVNYHGDTPLHIAARESYHDCVLLFLSRG 873
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 686 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 745
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 746 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 805
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 806 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 865
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 866 VLLFLSRGANPELRNKEGDTAWDLTPER 893
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 719 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 778
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 779 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 838
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 839 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 898
Query: 553 AATL 564
A L
Sbjct: 899 ALQL 902
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 784 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 843
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 844 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 889
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 850 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 909
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 910 VGNRAIRTE 918
>BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein.
Length = 1043
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 499 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 558
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 559 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 618
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 619 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 678
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 679 AVNYHGDTPLHIAARESYHDCVLLFLSRG 707
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 520 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 579
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 580 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 639
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 640 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 699
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 700 VLLFLSRGANPELRNKEGDTAWDLTPER 727
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 553 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 612
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 613 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 672
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 673 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 732
Query: 553 AATL 564
A L
Sbjct: 733 ALQL 736
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 618 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 677
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 678 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 723
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 684 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 743
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 744 VGNRAIRTE 752
>BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 457 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 516
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 636
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 637 AVNYHGDTPLHIAARESYHDCVLLFLSRG 665
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 657
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 658 VLLFLSRGANPELRNKEGDTAWDLTPER 685
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 570
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 571 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 630
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 631 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 690
Query: 553 AATL 564
A L
Sbjct: 691 ALQL 694
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 576 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 642 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 701
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 702 VGNRAIRTE 710
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 101 bits (243), Expect = 2e-21
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +1
Query: 55 IIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAA 234
+ +L + GA+ E +T H+A+ G+V+ +++ HG DV A ++ LH+AA
Sbjct: 27 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 86
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
K +H+ L++ P + G TALH AA G L+ +L H + + +G
Sbjct: 87 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 146
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL +A Q + LL+ GAD + K+G T L +A L++ GA N
Sbjct: 147 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLV 206
Query: 595 SKAGFTPLHLAAQQGHTEMCALLL 666
G+ LH + + + +LLL
Sbjct: 207 DSLGYNALHYSKLSENAGIQSLLL 230
Score = 89.4 bits (212), Expect = 1e-17
Identities = 50/171 (29%), Positives = 81/171 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T HLAA H + +R+++ +G V A+ + LH+A++ + + LLQ
Sbjct: 45 GKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPA 104
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ + LH AA Q L EH +P+ G L LA + G+ ++ + LL
Sbjct: 105 ESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 164
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
HGA + K+G T L +A + L++KGAD V G+ LH
Sbjct: 165 DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 215
Score = 81.8 bits (193), Expect = 2e-15
Identities = 46/141 (32%), Positives = 71/141 (50%)
Frame = +1
Query: 253 VAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
VA+ L + A T +G TA HLAA G+++ +++ HG G + LH+AA
Sbjct: 27 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 86
Query: 433 QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
+ LL+ A++V +G T LH AA + ++ L E+ + N + G
Sbjct: 87 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 146
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PL LA Q GH+E+C LL+ G
Sbjct: 147 PLLLAVQNGHSEICHFLLDHG 167
Score = 74.1 bits (174), Expect = 5e-13
Identities = 49/174 (28%), Positives = 78/174 (44%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+A LL + GA ++ H+AA + + + +I H +TA G +ALHLAA
Sbjct: 27 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 86
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT 513
K + + LL + +G T LH AA L E + +G+
Sbjct: 87 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 146
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
PL +A + E LL++GA N+ +K+G T L LA + G + L++ G
Sbjct: 147 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKG 200
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLAA+ +H + IR LL++ E+ +T LH A+ G + +L +H + +
Sbjct: 78 GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPI 137
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PL +A + + ++ L++H A + + K G TAL LA + G+ L+
Sbjct: 138 NLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALI 197
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK---GADAKAVAK 501
GA + G LH + + + + LL K AD K K
Sbjct: 198 KKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTK 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/107 (31%), Positives = 49/107 (45%)
Frame = +1
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
KVA+LL GA+ + G T H+AA ++ G D A GH+ LH+A
Sbjct: 26 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 85
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ + E LL+ + +G T LH AA QG + +L E
Sbjct: 86 AKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCE 132
Score = 53.6 bits (123), Expect = 7e-07
Identities = 31/97 (31%), Positives = 45/97 (46%)
Frame = +1
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAA 558
A ++ KN L D + VA+ L +KGA A G T H+AA K +E
Sbjct: 3 AKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLR 62
Query: 559 TLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
++ +G A+ G + LHLAA+ H E LL+
Sbjct: 63 VMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQ 99
Score = 30.3 bits (65), Expect = 7.5
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Frame = +1
Query: 526 AARKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A E A+LL + GA G T HLAA +GH E +++ G
Sbjct: 18 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 68
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 101 bits (243), Expect = 2e-21
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +1
Query: 55 IIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAA 234
+ +L + GA+ E +T H+A+ G+V+ +++ HG DV A ++ LH+AA
Sbjct: 38 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 97
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
K +H+ L++ P + G TALH AA G L+ +L H + + +G
Sbjct: 98 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 157
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL +A Q + LL+ GAD + K+G T L +A L++ GA N
Sbjct: 158 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLV 217
Query: 595 SKAGFTPLHLAAQQGHTEMCALLL 666
G+ LH + + + +LLL
Sbjct: 218 DSLGYNALHYSKLSENAGIQSLLL 241
Score = 89.4 bits (212), Expect = 1e-17
Identities = 50/171 (29%), Positives = 81/171 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T HLAA H + +R+++ +G V A+ + LH+A++ + + LLQ
Sbjct: 56 GKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPA 115
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ + LH AA Q L EH +P+ G L LA + G+ ++ + LL
Sbjct: 116 ESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 175
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
HGA + K+G T L +A + L++KGAD V G+ LH
Sbjct: 176 DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 226
Score = 81.8 bits (193), Expect = 2e-15
Identities = 46/141 (32%), Positives = 71/141 (50%)
Frame = +1
Query: 253 VAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
VA+ L + A T +G TA HLAA G+++ +++ HG G + LH+AA
Sbjct: 38 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 97
Query: 433 QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
+ LL+ A++V +G T LH AA + ++ L E+ + N + G
Sbjct: 98 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 157
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PL LA Q GH+E+C LL+ G
Sbjct: 158 PLLLAVQNGHSEICHFLLDHG 178
Score = 74.1 bits (174), Expect = 5e-13
Identities = 49/174 (28%), Positives = 78/174 (44%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+A LL + GA ++ H+AA + + + +I H +TA G +ALHLAA
Sbjct: 38 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 97
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT 513
K + + LL + +G T LH AA L E + +G+
Sbjct: 98 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 157
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
PL +A + E LL++GA N+ +K+G T L LA + G + L++ G
Sbjct: 158 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKG 211
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLAA+ +H + IR LL++ E+ +T LH A+ G + +L +H + +
Sbjct: 89 GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPI 148
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PL +A + + ++ L++H A + + K G TAL LA + G+ L+
Sbjct: 149 NLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALI 208
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK---GADAKAVAK 501
GA + G LH + + + + LL K AD K K
Sbjct: 209 KKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTK 255
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/107 (31%), Positives = 49/107 (45%)
Frame = +1
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
KVA+LL GA+ + G T H+AA ++ G D A GH+ LH+A
Sbjct: 37 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 96
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ + E LL+ + +G T LH AA QG + +L E
Sbjct: 97 AKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCE 143
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
KN L D + VA+ L +KGA A G T H+AA K +E ++ +G
Sbjct: 21 KNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGV 80
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ G + LHLAA+ H E LL+
Sbjct: 81 DVTAQDTTGHSALHLAAKNSHHECIRKLLQ 110
Score = 30.3 bits (65), Expect = 7.5
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Frame = +1
Query: 526 AARKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A E A+LL + GA G T HLAA +GH E +++ G
Sbjct: 29 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 79
>AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transcript
8 protein.
Length = 1210
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 666 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 725
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 845
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 846 AVNYHGDTPLHIAARESYHDCVLLFLSRG 874
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 866
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 867 VLLFLSRGANPELRNKEGDTAWDLTPER 894
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 779
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 780 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 839
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 840 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 899
Query: 553 AATL 564
A L
Sbjct: 900 ALQL 903
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 785 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 851 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 910
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 911 VGNRAIRTE 919
>AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transcript
8 protein.
Length = 1176
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 632 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 691
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 692 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 751
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 752 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 811
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 812 AVNYHGDTPLHIAARESYHDCVLLFLSRG 840
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 773 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 832
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 833 VLLFLSRGANPELRNKEGDTAWDLTPER 860
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 686 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 745
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 746 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 805
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 806 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 865
Query: 553 AATL 564
A L
Sbjct: 866 ALQL 869
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 751 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 810
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 811 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 817 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 876
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 877 VGNRAIRTE 885
>AL671762-16|CAI18226.2| 1176|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1176
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 632 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 691
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 692 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 751
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 752 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 811
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 812 AVNYHGDTPLHIAARESYHDCVLLFLSRG 840
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 773 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 832
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 833 VLLFLSRGANPELRNKEGDTAWDLTPER 860
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 686 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 745
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 746 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 805
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 806 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 865
Query: 553 AATL 564
A L
Sbjct: 866 ALQL 869
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 751 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 810
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 811 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 817 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 876
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 877 VGNRAIRTE 885
>AL671762-15|CAI18224.2| 1210|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1210
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 666 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 725
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 845
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 846 AVNYHGDTPLHIAARESYHDCVLLFLSRG 874
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 866
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 867 VLLFLSRGANPELRNKEGDTAWDLTPER 894
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 779
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 780 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 839
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 840 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 899
Query: 553 AATL 564
A L
Sbjct: 900 ALQL 903
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 785 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 851 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 910
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 911 VGNRAIRTE 919
>AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1267
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 723 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 782
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 783 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 842
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 843 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 902
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 903 AVNYHGDTPLHIAARESYHDCVLLFLSRG 931
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 803
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 804 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 863
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 864 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 923
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 924 VLLFLSRGANPELRNKEGDTAWDLTPER 951
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 777 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 836
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 837 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 896
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 897 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 956
Query: 553 AATL 564
A L
Sbjct: 957 ALQL 960
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 842 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 901
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 902 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 947
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 908 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 967
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 968 VGNRAIRTE 976
>AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1233
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 689 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 748
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 749 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 808
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 809 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 868
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 869 AVNYHGDTPLHIAARESYHDCVLLFLSRG 897
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 769
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 770 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 829
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 830 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 889
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 890 VLLFLSRGANPELRNKEGDTAWDLTPER 917
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 743 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 802
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 803 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 862
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 863 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 922
Query: 553 AATL 564
A L
Sbjct: 923 ALQL 926
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 808 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 867
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 868 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 913
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 874 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 933
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 934 VGNRAIRTE 942
>AL662834-27|CAI17748.1| 1210|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1210
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 666 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 725
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 845
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 846 AVNYHGDTPLHIAARESYHDCVLLFLSRG 874
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 866
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 867 VLLFLSRGANPELRNKEGDTAWDLTPER 894
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 779
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 780 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 839
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 840 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 899
Query: 553 AATL 564
A L
Sbjct: 900 ALQL 903
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 785 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 851 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 910
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 911 VGNRAIRTE 919
>AL662834-26|CAI17747.2| 1176|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1176
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 632 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 691
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 692 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 751
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 752 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 811
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 812 AVNYHGDTPLHIAARESYHDCVLLFLSRG 840
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 773 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 832
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 833 VLLFLSRGANPELRNKEGDTAWDLTPER 860
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 686 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 745
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 746 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 805
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 806 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 865
Query: 553 AATL 564
A L
Sbjct: 866 ALQL 869
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 751 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 810
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 811 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 817 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 876
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 877 VGNRAIRTE 885
>AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1267
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 723 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 782
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 783 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 842
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 843 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 902
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 903 AVNYHGDTPLHIAARESYHDCVLLFLSRG 931
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 803
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 804 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 863
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 864 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 923
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 924 VLLFLSRGANPELRNKEGDTAWDLTPER 951
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 777 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 836
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 837 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 896
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 897 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 956
Query: 553 AATL 564
A L
Sbjct: 957 ALQL 960
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 842 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 901
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 902 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 947
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 908 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 967
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 968 VGNRAIRTE 976
>AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 1233
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 689 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 748
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 749 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 808
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 809 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 868
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 869 AVNYHGDTPLHIAARESYHDCVLLFLSRG 897
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 769
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 770 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 829
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 830 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 889
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 890 VLLFLSRGANPELRNKEGDTAWDLTPER 917
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 743 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 802
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 803 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 862
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 863 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 922
Query: 553 AATL 564
A L
Sbjct: 923 ALQL 926
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 808 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 867
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 868 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 913
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 874 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 933
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 934 VGNRAIRTE 942
>AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ25613 fis, clone STM01546. ).
Length = 353
Score = 101 bits (243), Expect = 2e-21
Identities = 70/199 (35%), Positives = 90/199 (45%)
Frame = +1
Query: 79 GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVA 258
GA V AK PLH A+ N + LLL H ADV A PLH+AA A
Sbjct: 82 GANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCA 141
Query: 259 AALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQY 438
AL + L + G +ALH A G+L+ NLLL GA+ + K PLH AA
Sbjct: 142 EALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFL 201
Query: 439 DQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
V L+ +GAD + G+ LH AA Q+E LL GA + + G T L
Sbjct: 202 GHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTAL 261
Query: 619 HLAAQQGHTEMCALLLEGG 675
H+A G + L+ G
Sbjct: 262 HIACYLGQDAVAIELVNAG 280
Score = 101 bits (243), Expect = 2e-21
Identities = 71/216 (32%), Positives = 99/216 (45%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H AA + + ++ +LL + A V A+ + QTPLH+A+ A L + +
Sbjct: 95 PLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVA 154
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
+ LH A + + L+ A L KK LH AA G+L+V LL+A G
Sbjct: 155 DRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARG 214
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAA 558
A + G LH AA Q V LL GA+ G+T LHIA Q A
Sbjct: 215 ADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAI 274
Query: 559 TLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
L+ GA N + GFTPLH+AA + +C LL
Sbjct: 275 ELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELL 310
Score = 95.9 bits (228), Expect = 1e-19
Identities = 59/173 (34%), Positives = 82/173 (47%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
+TP+H+AA T L +++ R ++ LH A G+++ LLL GA +
Sbjct: 126 QTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLN 185
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
PLH AA + +V L+ A L +KG+ LH AA G ++V LL
Sbjct: 186 VCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLR 245
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
GA D+ G T LHIA Q AVA L+ GA+ G TPLH+AA
Sbjct: 246 MGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAA 298
Score = 85.8 bits (203), Expect = 1e-16
Identities = 50/153 (32%), Positives = 76/153 (49%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +H A + H + + +LL GA++ ++ + PLH A+ LG++++ LL+ GAD+
Sbjct: 158 GRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADL 217
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
Y LH AA +V L+ A + G TALH+A G VA L+
Sbjct: 218 GCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELV 277
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL 468
GA +Q G TPLH+AA A+ LL
Sbjct: 278 NAGANVNQPNDKGFTPLHVAAVSTNGALCLELL 310
Score = 64.9 bits (151), Expect = 3e-10
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+H AA H +++++L+ GA + K R+ LH A+ G +++ LL+ GA++
Sbjct: 194 PLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEP 253
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA-NLLLAH 375
A LHIA VA L+ A + KGFT LH+AA N + LL+ +
Sbjct: 254 NAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNN 313
Query: 376 GA 381
GA
Sbjct: 314 GA 315
Score = 56.0 bits (129), Expect = 1e-07
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G +H AA + ++++ LLR GA ++ T LHIA LG +A+ L+ GA+
Sbjct: 223 KGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGAN 282
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPL-----TATTKKGFTALHLAAKYGNLK 351
V + PLH+AA N + L+ +N ++ L K+ K
Sbjct: 283 VNQPNDKGFTPLHVAAVSTNGALCLELLVNNGAFYFNYNVIELERNIRILSCHLKFNKSK 342
Query: 352 VANLLLAHGAAP 387
+ L+ H AAP
Sbjct: 343 I-ELIFPHEAAP 353
>AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein.
Length = 1210
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 666 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 725
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 845
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 846 AVNYHGDTPLHIAARESYHDCVLLFLSRG 874
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 866
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 867 VLLFLSRGANPELRNKEGDTAWDLTPER 894
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 779
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 780 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 839
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 840 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 899
Query: 553 AATL 564
A L
Sbjct: 900 ALQL 903
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 785 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 851 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 910
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 911 VGNRAIRTE 919
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 101 bits (243), Expect = 2e-21
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +1
Query: 55 IIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAA 234
+ +L + GA+ E +T H+A+ G+V+ +++ HG DV A ++ LH+AA
Sbjct: 35 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 94
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
K +H+ L++ P + G TALH AA G L+ +L H + + +G
Sbjct: 95 KNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 154
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL +A Q + LL+ GAD + K+G T L +A L++ GA N
Sbjct: 155 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLV 214
Query: 595 SKAGFTPLHLAAQQGHTEMCALLL 666
G+ LH + + + +LLL
Sbjct: 215 DSLGYNALHYSKLSENAGIQSLLL 238
Score = 89.4 bits (212), Expect = 1e-17
Identities = 50/171 (29%), Positives = 81/171 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T HLAA H + +R+++ +G V A+ + LH+A++ + + LLQ
Sbjct: 53 GKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLLQSKCPA 112
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ + LH AA Q L EH +P+ G L LA + G+ ++ + LL
Sbjct: 113 ESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 172
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
HGA + K+G T L +A + L++KGAD V G+ LH
Sbjct: 173 DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 223
Score = 81.8 bits (193), Expect = 2e-15
Identities = 46/141 (32%), Positives = 71/141 (50%)
Frame = +1
Query: 253 VAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
VA+ L + A T +G TA HLAA G+++ +++ HG G + LH+AA
Sbjct: 35 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 94
Query: 433 QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
+ LL+ A++V +G T LH AA + ++ L E+ + N + G
Sbjct: 95 KNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 154
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PL LA Q GH+E+C LL+ G
Sbjct: 155 PLLLAVQNGHSEICHFLLDHG 175
Score = 74.1 bits (174), Expect = 5e-13
Identities = 49/174 (28%), Positives = 78/174 (44%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+A LL + GA ++ H+AA + + + +I H +TA G +ALHLAA
Sbjct: 35 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 94
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT 513
K + + LL + +G T LH AA L E + +G+
Sbjct: 95 KNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 154
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
PL +A + E LL++GA N+ +K+G T L LA + G + L++ G
Sbjct: 155 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKG 208
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLAA+ +H + IR LL++ E+ +T LH A+ G + +L +H + +
Sbjct: 86 GHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPI 145
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PL +A + + ++ L++H A + + K G TAL LA + G+ L+
Sbjct: 146 NLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALI 205
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK---GADAKAVAK 501
GA + G LH + + + + LL K AD K K
Sbjct: 206 KKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTK 252
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/107 (31%), Positives = 49/107 (45%)
Frame = +1
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
KVA+LL GA+ + G T H+AA ++ G D A GH+ LH+A
Sbjct: 34 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 93
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ + E LL+ + +G T LH AA QG + +L E
Sbjct: 94 AKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCE 140
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
KN L D + VA+ L +KGA A G T H+AA K +E ++ +G
Sbjct: 18 KNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGV 77
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ G + LHLAA+ H E LL+
Sbjct: 78 DVTAQDTTGHSALHLAAKNSHHECIRRLLQ 107
Score = 30.3 bits (65), Expect = 7.5
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Frame = +1
Query: 526 AARKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A E A+LL + GA G T HLAA +GH E +++ G
Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76
>AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 101 bits (243), Expect = 2e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 457 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 516
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTN 588
TP+ AA++ V LL +GAD + LH A+ A LL +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLH 636
Query: 589 AESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + G TPLH+AA++ + + L L G
Sbjct: 637 AVNYHGDTPLHIAARESYHDCVLLFLSRG 665
Score = 93.5 bits (222), Expect = 7e-19
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
GA LH A+ A+A LL D AV +G TPLHIAAR++ +
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDC 657
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQ 636
L GA +K G T L ++
Sbjct: 658 VLLFLSRGANPELRNKEGDTAWDLTPER 685
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 570
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A + + P+ AA+ + +V L+ A +T T + LH A+ G+ +A +LL
Sbjct: 571 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 630
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G TPLHIAA+ L +GA+ + K G T + ++ +
Sbjct: 631 ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWF 690
Query: 553 AATL 564
A L
Sbjct: 691 ALQL 694
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/106 (36%), Positives = 51/106 (48%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AA H ++IR+LL GA V E LH AS G+ IA +LL D+
Sbjct: 576 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
A+ PLHIAA++ HD + A K+G TA L
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 642 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 701
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 702 VGNRAIRTE 710
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 101 bits (243), Expect = 2e-21
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +1
Query: 55 IIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAA 234
+ +L + GA+ E +T H+A+ G+V+ +++ HG DV A ++ LH+AA
Sbjct: 44 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 103
Query: 235 KQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMT 414
K +H+ L++ P + G TALH AA G L+ +L H + + +G
Sbjct: 104 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 163
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL +A Q + LL+ GAD + K+G T L +A L++ GA N
Sbjct: 164 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLV 223
Query: 595 SKAGFTPLHLAAQQGHTEMCALLL 666
G+ LH + + + +LLL
Sbjct: 224 DSLGYNALHYSKLSENAGIQSLLL 247
Score = 89.4 bits (212), Expect = 1e-17
Identities = 50/171 (29%), Positives = 81/171 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+T HLAA H + +R+++ +G V A+ + LH+A++ + + LLQ
Sbjct: 62 GKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPA 121
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
++ + LH AA Q L EH +P+ G L LA + G+ ++ + LL
Sbjct: 122 ESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 181
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
HGA + K+G T L +A + L++KGAD V G+ LH
Sbjct: 182 DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 232
Score = 81.8 bits (193), Expect = 2e-15
Identities = 46/141 (32%), Positives = 71/141 (50%)
Frame = +1
Query: 253 VAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAA 432
VA+ L + A T +G TA HLAA G+++ +++ HG G + LH+AA
Sbjct: 44 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 103
Query: 433 QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFT 612
+ LL+ A++V +G T LH AA + ++ L E+ + N + G
Sbjct: 104 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 163
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PL LA Q GH+E+C LL+ G
Sbjct: 164 PLLLAVQNGHSEICHFLLDHG 184
Score = 74.1 bits (174), Expect = 5e-13
Identities = 49/174 (28%), Positives = 78/174 (44%)
Frame = +1
Query: 154 IAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAA 333
+A LL + GA ++ H+AA + + + +I H +TA G +ALHLAA
Sbjct: 44 VASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAA 103
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT 513
K + + LL + +G T LH AA L E + +G+
Sbjct: 104 KNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNI 163
Query: 514 PLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
PL +A + E LL++GA N+ +K+G T L LA + G + L++ G
Sbjct: 164 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKG 217
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +HLAA+ +H + IR LL++ E+ +T LH A+ G + +L +H + +
Sbjct: 95 GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPI 154
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D PL +A + + ++ L++H A + + K G TAL LA + G+ L+
Sbjct: 155 NLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALI 214
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK---GADAKAVAK 501
GA + G LH + + + + LL K AD K K
Sbjct: 215 KKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTK 261
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/107 (31%), Positives = 49/107 (45%)
Frame = +1
Query: 349 KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIA 528
KVA+LL GA+ + G T H+AA ++ G D A GH+ LH+A
Sbjct: 43 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 102
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ + E LL+ + +G T LH AA QG + +L E
Sbjct: 103 AKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCE 149
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Frame = +1
Query: 400 KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA 579
KN L D + VA+ L +KGA A G T H+AA K +E ++ +G
Sbjct: 27 KNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGV 86
Query: 580 LTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A+ G + LHLAA+ H E LL+
Sbjct: 87 DVTAQDTTGHSALHLAAKNSHHECIRKLLQ 116
Score = 30.3 bits (65), Expect = 7.5
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Frame = +1
Query: 526 AARKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A E A+LL + GA G T HLAA +GH E +++ G
Sbjct: 35 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 85
>AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 100 bits (240), Expect = 5e-21
Identities = 65/195 (33%), Positives = 96/195 (49%)
Frame = +1
Query: 94 AKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIE 273
A R +++ LHIA+ G+V+ VLLL+ GA+ PLH+AA+ + L+E
Sbjct: 60 AFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLE 119
Query: 274 HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
++A + +G TA+H A G ++ + L+ H + D G T LH+A
Sbjct: 120 YSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVA------CT 173
Query: 454 ATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
LL+ GAD +G TPL+ A Q +TA LL GA K G TPL L Q
Sbjct: 174 VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQ 232
Query: 634 QGHTEMCALLLEGGP 678
G+ E C +L++ P
Sbjct: 233 GGYGETCEVLIQYHP 247
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/184 (29%), Positives = 85/184 (46%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AA + + +LL+ GA + TPLH+A+R G LL++ ADV
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ +H A ++ L++H + + G TALH+A LL GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVAC------TVQCLLDSGA 182
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
++ +G TPL+ A + Q+ A LL +GA KNG TPL + + ET
Sbjct: 183 DINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQGGYGETCEV 241
Query: 562 LLEY 573
L++Y
Sbjct: 242 LIQY 245
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/146 (31%), Positives = 64/146 (43%), Gaps = 2/146 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+HLAAR + LL A V E T +H + G ++ L+QH +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
DV A LH+A L++ A + G T L+ A +G A +
Sbjct: 156 DVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 209
Query: 364 LLAHGA--APDQAGKNGMTPLHIAAQ 435
LL GA PD KNG+TPL + Q
Sbjct: 210 LLLRGAKYLPD---KNGVTPLDLCVQ 232
>AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 100 bits (240), Expect = 5e-21
Identities = 65/195 (33%), Positives = 96/195 (49%)
Frame = +1
Query: 94 AKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIE 273
A R +++ LHIA+ G+V+ VLLL+ GA+ PLH+AA+ + L+E
Sbjct: 60 AFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLE 119
Query: 274 HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
++A + +G TA+H A G ++ + L+ H + D G T LH+A
Sbjct: 120 YSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVA------CT 173
Query: 454 ATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
LL+ GAD +G TPL+ A Q +TA LL GA K G TPL L Q
Sbjct: 174 VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQ 232
Query: 634 QGHTEMCALLLEGGP 678
G+ E C +L++ P
Sbjct: 233 GGYGETCEVLIQYHP 247
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/184 (29%), Positives = 85/184 (46%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AA + + +LL+ GA + TPLH+A+R G LL++ ADV
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ +H A ++ L++H + + G TALH+A LL GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVAC------TVQCLLDSGA 182
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
++ +G TPL+ A + Q+ A LL +GA KNG TPL + + ET
Sbjct: 183 DINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQGGYGETCEV 241
Query: 562 LLEY 573
L++Y
Sbjct: 242 LIQY 245
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/146 (31%), Positives = 64/146 (43%), Gaps = 2/146 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+HLAAR + LL A V E T +H + G ++ L+QH +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
DV A LH+A L++ A + G T L+ A +G A +
Sbjct: 156 DVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 209
Query: 364 LLAHGA--APDQAGKNGMTPLHIAAQ 435
LL GA PD KNG+TPL + Q
Sbjct: 210 LLLRGAKYLPD---KNGVTPLDLCVQ 232
>AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 100 bits (240), Expect = 5e-21
Identities = 65/195 (33%), Positives = 96/195 (49%)
Frame = +1
Query: 94 AKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIE 273
A R +++ LHIA+ G+V+ VLLL+ GA+ PLH+AA+ + L+E
Sbjct: 60 AFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLE 119
Query: 274 HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAV 453
++A + +G TA+H A G ++ + L+ H + D G T LH+A
Sbjct: 120 YSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVA------CT 173
Query: 454 ATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
LL+ GAD +G TPL+ A Q +TA LL GA K G TPL L Q
Sbjct: 174 VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQ 232
Query: 634 QGHTEMCALLLEGGP 678
G+ E C +L++ P
Sbjct: 233 GGYGETCEVLIQYHP 247
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/184 (29%), Positives = 85/184 (46%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAIT 201
+H+AA + + +LL+ GA + TPLH+A+R G LL++ ADV
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 202 ADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGA 381
+ +H A ++ L++H + + G TALH+A LL GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVAC------TVQCLLDSGA 182
Query: 382 APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAAT 561
++ +G TPL+ A + Q+ A LL +GA KNG TPL + + ET
Sbjct: 183 DINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDLCVQGGYGETCEV 241
Query: 562 LLEY 573
L++Y
Sbjct: 242 LIQY 245
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/146 (31%), Positives = 64/146 (43%), Gaps = 2/146 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+ G TP+HLAAR + LL A V E T +H + G ++ L+QH +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
DV A LH+A L++ A + G T L+ A +G A +
Sbjct: 156 DVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 209
Query: 364 LLAHGA--APDQAGKNGMTPLHIAAQ 435
LL GA PD KNG+TPL + Q
Sbjct: 210 LLLRGAKYLPD---KNGVTPLDLCVQ 232
>AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens
cDNA FLJ25053 fis, clone CBL04266. ).
Length = 268
Score = 99.5 bits (237), Expect = 1e-20
Identities = 72/210 (34%), Positives = 99/210 (47%), Gaps = 1/210 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +AA A H D +R L+ GA + + T L A++ G+ D+ L GA
Sbjct: 46 GTTLLMVAAYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGAST 105
Query: 190 RAITADHYNPLHIAAKQHNH-DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
T D L +AA Q+ H V L++H A + G TAL LAA+ G L V LL
Sbjct: 106 EFRTKDGGTAL-LAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLL 164
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
LA GA +Q ++G PL IA+Q V +L +GAD A +G T L AA K
Sbjct: 165 LASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYN 224
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
+ LL++ T KA P L +
Sbjct: 225 DVIKELLKFSP-TLGILKANELPAELTKNE 253
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/217 (31%), Positives = 104/217 (47%), Gaps = 1/217 (0%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAA-VEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITAD 207
AAR + ++++LL +G V+ + T L +A+ G++D L+ GAD+
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRES 78
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAP 387
L AA+Q ++DV L A TK G TAL A++YG+++V LL HGA
Sbjct: 79 GTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDGGTALLAASQYGHMQVVETLLKHGANI 138
Query: 388 DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLL 567
+G T L +AAQ V LL GA ++G PL IA++ E +L
Sbjct: 139 HDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVML 198
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
GA +A G T L AA +G+ ++ LL+ P
Sbjct: 199 LRGADRDAARNDGTTALLKAANKGYNDVIKELLKFSP 235
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Frame = +1
Query: 427 AAQYDQQAVATTLLEKG-ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKA 603
AA+ A+ LL G D +G T L +AA ++ L+ GA N + ++
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRES 78
Query: 604 GFTPLHLAAQQGHTEMCALLLEGGPGTQF 690
G T L AAQQGH ++ L G T+F
Sbjct: 79 GTTALFFAAQQGHNDVVRFLFGFGASTEF 107
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 98.7 bits (235), Expect = 2e-20
Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G TP+H AA H D++ +LLRN A + PLH+A+ G+ I LL+ G
Sbjct: 126 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 185
Query: 187 --VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V D+ LH AA+ + +V L+E T K T L LAA YG L+V
Sbjct: 186 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 245
Query: 361 LLLAHGAAPDQAGKNGM--TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL A P+ N TPLH+AA+ +AV LL+ G D+ + G + LH AA
Sbjct: 246 MLL--NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAAL 302
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPL 618
+ + LL G N + G T L
Sbjct: 303 FGKTDVVQILLAAGTDVNIKDNHGLTAL 330
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G+ D+ +LL++ A + PLH+AA + + + LI T
Sbjct: 128 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 187
Query: 295 TTKKGF---TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
++ TALH AA+YG+ +V +LL P TPL +AA Y + V L
Sbjct: 188 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 247
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L + + HTPLH+AAR LL+ G +N +++ G + LH AA G T
Sbjct: 248 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKT 306
Query: 646 EMCALLLEGG 675
++ +LL G
Sbjct: 307 DVVQILLAAG 316
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 4/182 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK 336
++L + G +V + + Y PLH AA + DV L+ ++A KG LHLAA
Sbjct: 109 SLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAW 168
Query: 337 YGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
G+ ++ LL+ G + ++ + T LH AAQY V LLE+ D
Sbjct: 169 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 228
Query: 508 HTPLHIAARKNQMETAATLLE-YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
TPL +AA ++E LL + L + +K TPLHLAA+ GH + +LL+ G +
Sbjct: 229 ETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNGHKAVVQVLLDAGMDS 287
Query: 685 QF 690
+
Sbjct: 288 NY 289
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/145 (27%), Positives = 73/145 (50%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET +H AA+ HT+++++LL + + +TPL +A+ G +++ +LL ++
Sbjct: 196 ETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLL 255
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PLH+AA+ + V L++ T+ G +ALH AA +G V +LLA
Sbjct: 256 SCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 314
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
G + +G+T L + Q
Sbjct: 315 AGTDVNIKDNHGLTALDTVRELPSQ 339
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/174 (29%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA I+R+L+ G + V + + +T LH A++ G+ ++ +LL+
Sbjct: 158 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 217
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D PL +AA +V L+ + L + K T LHLAA+ G+ V
Sbjct: 218 LTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVV 277
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
+LL G + + G + LH AA + + V LL G D +G T L
Sbjct: 278 QVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 330
Score = 31.1 bits (67), Expect = 4.3
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = +1
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
G N G+TPLH AA GH ++ +LL T A
Sbjct: 116 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVA 155
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 98.7 bits (235), Expect = 2e-20
Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G TP+H AA H D++ +LLRN A + PLH+A+ G+ I LL+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 187 --VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V D+ LH AA+ + +V L+E T K T L LAA YG L+V
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 361 LLLAHGAAPDQAGKNGM--TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL A P+ N TPLH+AA+ +AV LL+ G D+ + G + LH AA
Sbjct: 200 MLL--NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAAL 256
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPL 618
+ + LL G N + G T L
Sbjct: 257 FGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G+ D+ +LL++ A + PLH+AA + + + LI T
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 295 TTKKGF---TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
++ TALH AA+YG+ +V +LL P TPL +AA Y + V L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L + + HTPLH+AAR LL+ G +N +++ G + LH AA G T
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKT 260
Query: 646 EMCALLLEGG 675
++ +LL G
Sbjct: 261 DVVQILLAAG 270
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 4/182 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK 336
++L + G +V + + Y PLH AA + DV L+ ++A KG LHLAA
Sbjct: 63 SLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAW 122
Query: 337 YGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
G+ ++ LL+ G + ++ + T LH AAQY V LLE+ D
Sbjct: 123 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 182
Query: 508 HTPLHIAARKNQMETAATLLE-YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
TPL +AA ++E LL + L + +K TPLHLAA+ GH + +LL+ G +
Sbjct: 183 ETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNGHKAVVQVLLDAGMDS 241
Query: 685 QF 690
+
Sbjct: 242 NY 243
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/145 (27%), Positives = 73/145 (50%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET +H AA+ HT+++++LL + + +TPL +A+ G +++ +LL ++
Sbjct: 150 ETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLL 209
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PLH+AA+ + V L++ T+ G +ALH AA +G V +LLA
Sbjct: 210 SCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 268
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
G + +G+T L + Q
Sbjct: 269 AGTDVNIKDNHGLTALDTVRELPSQ 293
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/174 (29%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA I+R+L+ G + V + + +T LH A++ G+ ++ +LL+
Sbjct: 112 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D PL +AA +V L+ + L + K T LHLAA+ G+ V
Sbjct: 172 LTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVV 231
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
+LL G + + G + LH AA + + V LL G D +G T L
Sbjct: 232 QVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 31.1 bits (67), Expect = 4.3
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = +1
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
G N G+TPLH AA GH ++ +LL T A
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVA 109
>BC065710-1|AAH65710.1| 329|Homo sapiens ankyrin repeat and SOCS
box-containing 5 protein.
Length = 329
Score = 98.7 bits (235), Expect = 2e-20
Identities = 74/227 (32%), Positives = 106/227 (46%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA +R LL G V A + TPLH A +V A LL+ GA+V A
Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT D PL A Q + A L+E+ A + + H AA G+ + ++L++
Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLP-SPTHEAASKGHHECLDILISW 190
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G DQ + TPL++A Q LL GAD + K TPLH AA+++ E
Sbjct: 191 GIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK-GKYWDTPLHAAAQQSSTEIV 249
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LLE+GA NA++ P+ +A E L E P + + L
Sbjct: 250 NLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQL 296
Score = 89.8 bits (213), Expect = 9e-18
Identities = 67/188 (35%), Positives = 85/188 (45%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
++PLH A+ G + LL G +V A+T DH PLH A + A L+E A +
Sbjct: 71 RSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVN 130
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A T G T L A G+ A LLL +GA Q +P H AA L+
Sbjct: 131 AITIDGVTPLFNACSQGSPSCAELLLEYGAKA-QLESCLPSPTHEAASKGHHECLDILIS 189
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
G D + TPL++A Q LL GA + K TPLH AAQQ TE+
Sbjct: 190 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQSSTEI 248
Query: 652 CALLLEGG 675
LLLE G
Sbjct: 249 VNLLLEFG 256
Score = 64.5 bits (150), Expect = 4e-10
Identities = 46/124 (37%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Frame = +1
Query: 322 HLAAKYGNLKVANLLLA--HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
H GN K A + A +G Q +PLH AA + TLL +G + AV
Sbjct: 40 HFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAV 99
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ TPLH A + + A TLLE GA NA + G TPL A QG LLLE G
Sbjct: 100 TLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYG 159
Query: 676 PGTQ 687
Q
Sbjct: 160 AKAQ 163
>BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for
IMAGE:4618556) protein.
Length = 472
Score = 98.7 bits (235), Expect = 2e-20
Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G TP+H AA H D++ +LLRN A + PLH+A+ G+ I LL+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 187 --VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V D+ LH AA+ + +V L+E T K T L LAA YG L+V
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 361 LLLAHGAAPDQAGKNGM--TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL A P+ N TPLH+AA+ +AV LL+ G D+ + G + LH AA
Sbjct: 200 MLL--NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAAL 256
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPL 618
+ + LL G N + G T L
Sbjct: 257 FGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G+ D+ +LL++ A + PLH+AA + + + LI T
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 295 TTKKGF---TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
++ TALH AA+YG+ +V +LL P TPL +AA Y + V L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L + + HTPLH+AAR LL+ G +N +++ G + LH AA G T
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKT 260
Query: 646 EMCALLLEGG 675
++ +LL G
Sbjct: 261 DVVQILLAAG 270
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 4/182 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK 336
++L + G +V + + Y PLH AA + DV L+ ++A KG LHLAA
Sbjct: 63 SLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAW 122
Query: 337 YGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
G+ ++ LL+ G + ++ + T LH AAQY V LLE+ D
Sbjct: 123 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 182
Query: 508 HTPLHIAARKNQMETAATLLE-YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
TPL +AA ++E LL + L + +K TPLHLAA+ GH + +LL+ G +
Sbjct: 183 ETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNGHKAVVQVLLDAGMDS 241
Query: 685 QF 690
+
Sbjct: 242 NY 243
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/145 (27%), Positives = 73/145 (50%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET +H AA+ HT+++++LL + + +TPL +A+ G +++ +LL ++
Sbjct: 150 ETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLL 209
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PLH+AA+ + V L++ T+ G +ALH AA +G V +LLA
Sbjct: 210 SCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 268
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
G + +G+T L + Q
Sbjct: 269 AGTDVNIKDNHGLTALDTVRELPSQ 293
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/174 (29%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA I+R+L+ G + V + + +T LH A++ G+ ++ +LL+
Sbjct: 112 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D PL +AA +V L+ + L + K T LHLAA+ G+ V
Sbjct: 172 LTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVV 231
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
+LL G + + G + LH AA + + V LL G D +G T L
Sbjct: 232 QVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 31.1 bits (67), Expect = 4.3
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = +1
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
G N G+TPLH AA GH ++ +LL T A
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVA 109
>AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein.
Length = 1249
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/208 (31%), Positives = 100/208 (48%), Gaps = 3/208 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG--- 180
G T +H AA H DI+ LL+ A+ + P+H+A+ G+V+I +L+ HG
Sbjct: 59 GYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSH 118
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ V ++ LH AA+ + +V A L+E T K T L LAA YG L+V
Sbjct: 119 SRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVK 178
Query: 361 LLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
++++ TPLH+AA+ +AV LLE G D + G + LH AA
Sbjct: 179 MIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKG-SALHEAALFG 237
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHL 624
+++ LLE G N + G T L +
Sbjct: 238 KVDVVRVLLETGIDANIKDSLGRTVLDI 265
Score = 92.3 bits (219), Expect = 2e-18
Identities = 60/190 (31%), Positives = 93/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEH---NAP 285
T LH A+ G+ DI + LLQ+ A Y P+H+AA + + ++ LI H ++
Sbjct: 61 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR 120
Query: 286 LTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
+ + TALH AA+YG+ +V +LL P TPL +AA Y + V +
Sbjct: 121 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI 180
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
+ + + HTPLH+AAR LLE G + +++ G + LH AA G
Sbjct: 181 ISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKG-SALHEAALFGKV 239
Query: 646 EMCALLLEGG 675
++ +LLE G
Sbjct: 240 DVVRVLLETG 249
Score = 87.4 bits (207), Expect = 5e-17
Identities = 51/175 (29%), Positives = 82/175 (46%), Gaps = 3/175 (1%)
Frame = +1
Query: 160 VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKY 339
+L + G +V + Y LH AA + D+ L+++ A KG+ +HLAA
Sbjct: 43 LLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWK 102
Query: 340 GNLKVANLLLAHG---AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
G++++ +L+ HG + ++ T LH AAQY V LLE+ D
Sbjct: 103 GDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLE 162
Query: 511 TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
TPL +AA ++ ++ + + TPLHLAA+ GH + +LLE G
Sbjct: 163 TPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAG 217
Score = 79.0 bits (186), Expect = 2e-14
Identities = 58/195 (29%), Positives = 91/195 (46%), Gaps = 6/195 (3%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNG---AAVEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA +I++IL+ +G + V + E +T LH A++ G+ ++ +LL+
Sbjct: 91 KGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEE 150
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D + PL +AA V +I + L + + T LHLAA+ G+ V
Sbjct: 151 LTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVV 210
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR- 534
+LL G + G + LH AA + + V LLE G DA G T L I
Sbjct: 211 QVLLEAGMDVSCQTEKG-SALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEH 269
Query: 535 --KNQMETAATLLEY 573
+ ++ A L EY
Sbjct: 270 PSQKSLQIATLLQEY 284
Score = 52.8 bits (121), Expect = 1e-06
Identities = 24/69 (34%), Positives = 36/69 (52%)
Frame = +1
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
+G + +G+T LH AA + LL+Y A TN G+ P+HLAA +G E+
Sbjct: 48 RGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEI 107
Query: 652 CALLLEGGP 678
+L+ GP
Sbjct: 108 VKILIHHGP 116
>AY057053-1|AAL18248.1| 329|Homo sapiens SOCS box protein ASB-5
protein.
Length = 329
Score = 98.7 bits (235), Expect = 2e-20
Identities = 74/227 (32%), Positives = 106/227 (46%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA +R LL G V A + TPLH A +V A LL+ GA+V A
Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT D PL A Q + A L+E+ A + + H AA G+ + ++L++
Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLP-SPTHEAASKGHHECLDILISW 190
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G DQ + TPL++A Q LL GAD + K TPLH AA+++ E
Sbjct: 191 GIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK-GKYWDTPLHAAAQQSSTEIV 249
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LLE+GA NA++ P+ +A E L E P + + L
Sbjct: 250 NLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQL 296
Score = 89.8 bits (213), Expect = 9e-18
Identities = 67/188 (35%), Positives = 85/188 (45%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
++PLH A+ G + LL G +V A+T DH PLH A + A L+E A +
Sbjct: 71 RSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVN 130
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A T G T L A G+ A LLL +GA Q +P H AA L+
Sbjct: 131 AITIDGVTPLFNACSQGSPSCAELLLEYGAKA-QLESCLPSPTHEAASKGHHECLDILIS 189
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
G D + TPL++A Q LL GA + K TPLH AAQQ TE+
Sbjct: 190 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQSSTEI 248
Query: 652 CALLLEGG 675
LLLE G
Sbjct: 249 VNLLLEFG 256
Score = 64.5 bits (150), Expect = 4e-10
Identities = 46/124 (37%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Frame = +1
Query: 322 HLAAKYGNLKVANLLLA--HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
H GN K A + A +G Q +PLH AA + TLL +G + AV
Sbjct: 40 HFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAV 99
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ TPLH A + + A TLLE GA NA + G TPL A QG LLLE G
Sbjct: 100 TLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYG 159
Query: 676 PGTQ 687
Q
Sbjct: 160 AKAQ 163
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 98.7 bits (235), Expect = 2e-20
Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G TP+H AA H D++ +LLRN A + PLH+A+ G+ I LL+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 187 --VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V D+ LH AA+ + +V L+E T K T L LAA YG L+V
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 361 LLLAHGAAPDQAGKNGM--TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL A P+ N TPLH+AA+ +AV LL+ G D+ + G + LH AA
Sbjct: 200 MLL--NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAAL 256
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPL 618
+ + LL G N + G T L
Sbjct: 257 FGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G+ D+ +LL++ A + PLH+AA + + + LI T
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 295 TTKKGF---TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
++ TALH AA+YG+ +V +LL P TPL +AA Y + V L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L + + HTPLH+AAR LL+ G +N +++ G + LH AA G T
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKT 260
Query: 646 EMCALLLEGG 675
++ +LL G
Sbjct: 261 DVVQILLAAG 270
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 4/182 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK 336
++L + G +V + + Y PLH AA + DV L+ ++A KG LHLAA
Sbjct: 63 SLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAW 122
Query: 337 YGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
G+ ++ LL+ G + ++ + T LH AAQY V LLE+ D
Sbjct: 123 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 182
Query: 508 HTPLHIAARKNQMETAATLLE-YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
TPL +AA ++E LL + L + +K TPLHLAA+ GH + +LL+ G +
Sbjct: 183 ETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNGHKAVVQVLLDAGMDS 241
Query: 685 QF 690
+
Sbjct: 242 NY 243
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/145 (27%), Positives = 73/145 (50%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET +H AA+ HT+++++LL + + +TPL +A+ G +++ +LL ++
Sbjct: 150 ETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLL 209
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PLH+AA+ + V L++ T+ G +ALH AA +G V +LLA
Sbjct: 210 SCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 268
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
G + +G+T L + Q
Sbjct: 269 AGTDVNIKDNHGLTALDTVRELPSQ 293
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/174 (29%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA I+R+L+ G + V + + +T LH A++ G+ ++ +LL+
Sbjct: 112 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D PL +AA +V L+ + L + K T LHLAA+ G+ V
Sbjct: 172 LTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVV 231
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
+LL G + + G + LH AA + + V LL G D +G T L
Sbjct: 232 QVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 31.1 bits (67), Expect = 4.3
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = +1
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
G N G+TPLH AA GH ++ +LL T A
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVA 109
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 98.7 bits (235), Expect = 2e-20
Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G TP+H AA H D++ +LLRN A + PLH+A+ G+ I LL+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 187 --VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V D+ LH AA+ + +V L+E T K T L LAA YG L+V
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 361 LLLAHGAAPDQAGKNGM--TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL A P+ N TPLH+AA+ +AV LL+ G D+ + G + LH AA
Sbjct: 200 MLL--NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAAL 256
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPL 618
+ + LL G N + G T L
Sbjct: 257 FGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G+ D+ +LL++ A + PLH+AA + + + LI T
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 295 TTKKGF---TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
++ TALH AA+YG+ +V +LL P TPL +AA Y + V L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L + + HTPLH+AAR LL+ G +N +++ G + LH AA G T
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKT 260
Query: 646 EMCALLLEGG 675
++ +LL G
Sbjct: 261 DVVQILLAAG 270
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 4/182 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK 336
++L + G +V + + Y PLH AA + DV L+ ++A KG LHLAA
Sbjct: 63 SLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAW 122
Query: 337 YGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
G+ ++ LL+ G + ++ + T LH AAQY V LLE+ D
Sbjct: 123 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 182
Query: 508 HTPLHIAARKNQMETAATLLE-YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
TPL +AA ++E LL + L + +K TPLHLAA+ GH + +LL+ G +
Sbjct: 183 ETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNGHKAVVQVLLDAGMDS 241
Query: 685 QF 690
+
Sbjct: 242 NY 243
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/145 (27%), Positives = 73/145 (50%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET +H AA+ HT+++++LL + + +TPL +A+ G +++ +LL ++
Sbjct: 150 ETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLL 209
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PLH+AA+ + V L++ T+ G +ALH AA +G V +LLA
Sbjct: 210 SCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 268
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
G + +G+T L + Q
Sbjct: 269 AGTDVNIKDNHGLTALDTVRELPSQ 293
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/174 (29%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA I+R+L+ G + V + + +T LH A++ G+ ++ +LL+
Sbjct: 112 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D PL +AA +V L+ + L + K T LHLAA+ G+ V
Sbjct: 172 LTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVV 231
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
+LL G + + G + LH AA + + V LL G D +G T L
Sbjct: 232 QVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 31.1 bits (67), Expect = 4.3
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = +1
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
G N G+TPLH AA GH ++ +LL T A
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVA 109
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 98.7 bits (235), Expect = 2e-20
Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD- 186
G TP+H AA H D++ +LLRN A + PLH+A+ G+ I LL+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 187 --VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
V D+ LH AA+ + +V L+E T K T L LAA YG L+V
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 361 LLLAHGAAPDQAGKNGM--TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
+LL A P+ N TPLH+AA+ +AV LL+ G D+ + G + LH AA
Sbjct: 200 MLL--NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAAL 256
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPL 618
+ + LL G N + G T L
Sbjct: 257 FGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
TPLH A+ G+ D+ +LL++ A + PLH+AA + + + LI T
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 295 TTKKGF---TALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTL 465
++ TALH AA+YG+ +V +LL P TPL +AA Y + V L
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 466 LEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHT 645
L + + HTPLH+AAR LL+ G +N +++ G + LH AA G T
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKT 260
Query: 646 EMCALLLEGG 675
++ +LL G
Sbjct: 261 DVVQILLAAG 270
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 4/182 (2%)
Frame = +1
Query: 157 AVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK 336
++L + G +V + + Y PLH AA + DV L+ ++A KG LHLAA
Sbjct: 63 SLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAW 122
Query: 337 YGNLKVANLLLAHGAA---PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG 507
G+ ++ LL+ G + ++ + T LH AAQY V LLE+ D
Sbjct: 123 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 182
Query: 508 HTPLHIAARKNQMETAATLLE-YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGT 684
TPL +AA ++E LL + L + +K TPLHLAA+ GH + +LL+ G +
Sbjct: 183 ETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNGHKAVVQVLLDAGMDS 241
Query: 685 QF 690
+
Sbjct: 242 NY 243
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/145 (27%), Positives = 73/145 (50%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
ET +H AA+ HT+++++LL + + +TPL +A+ G +++ +LL ++
Sbjct: 150 ETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLL 209
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ + PLH+AA+ + V L++ T+ G +ALH AA +G V +LLA
Sbjct: 210 SCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLA 268
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
G + +G+T L + Q
Sbjct: 269 AGTDVNIKDNHGLTALDTVRELPSQ 293
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/174 (29%), Positives = 81/174 (46%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA---VEAKARERQTPLHIASRLGNVDIAVLLLQH 177
+G P+HLAA I+R+L+ G + V + + +T LH A++ G+ ++ +LL+
Sbjct: 112 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVA 357
D PL +AA +V L+ + L + K T LHLAA+ G+ V
Sbjct: 172 LTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVV 231
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPL 519
+LL G + + G + LH AA + + V LL G D +G T L
Sbjct: 232 QVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTAL 284
Score = 31.1 bits (67), Expect = 4.3
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = +1
Query: 574 GALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
G N G+TPLH AA GH ++ +LL T A
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVA 109
>AK098693-1|BAC05382.1| 276|Homo sapiens protein ( Homo sapiens
cDNA FLJ25827 fis, clone TST08047. ).
Length = 276
Score = 98.7 bits (235), Expect = 2e-20
Identities = 74/227 (32%), Positives = 106/227 (46%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA +R LL G V A + TPLH A +V A LL+ GA+V A
Sbjct: 19 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 78
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT D PL A Q + A L+E+ A + + H AA G+ + ++L++
Sbjct: 79 ITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLP-SPTHEAASKGHHECLDILISW 137
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G DQ + TPL++A Q LL GAD + K TPLH AA+++ E
Sbjct: 138 GIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK-GKYWDTPLHAAAQQSSTEIV 196
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LLE+GA NA++ P+ +A E L E P + + L
Sbjct: 197 NLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQL 243
Score = 89.8 bits (213), Expect = 9e-18
Identities = 67/188 (35%), Positives = 85/188 (45%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
++PLH A+ G + LL G +V A+T DH PLH A + A L+E A +
Sbjct: 18 RSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVN 77
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A T G T L A G+ A LLL +GA Q +P H AA L+
Sbjct: 78 AITIDGVTPLFNACSQGSPSCAELLLEYGAKA-QLESCLPSPTHEAASKGHHECLDILIS 136
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
G D + TPL++A Q LL GA + K TPLH AAQQ TE+
Sbjct: 137 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQSSTEI 195
Query: 652 CALLLEGG 675
LLLE G
Sbjct: 196 VNLLLEFG 203
>AK096441-1|BAC04791.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ39122 fis, clone NTONG2006783, weakly similar to
ANKYRIN 1. ).
Length = 329
Score = 98.7 bits (235), Expect = 2e-20
Identities = 74/227 (32%), Positives = 106/227 (46%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA +R LL G V A + TPLH A +V A LL+ GA+V A
Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
IT D PL A Q + A L+E+ A + + H AA G+ + ++L++
Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLP-SPTHEAASKGHHECLDILISW 190
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G DQ + TPL++A Q LL GAD + K TPLH AA+++ E
Sbjct: 191 GIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK-GKYWDTPLHAAAQQSSTEIV 249
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFAL 696
LLE+GA NA++ P+ +A E L E P + + L
Sbjct: 250 NLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQL 296
Score = 89.8 bits (213), Expect = 9e-18
Identities = 67/188 (35%), Positives = 85/188 (45%)
Frame = +1
Query: 112 QTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLT 291
++PLH A+ G + LL G +V A+T DH PLH A + A L+E A +
Sbjct: 71 RSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVN 130
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE 471
A T G T L A G+ A LLL +GA Q +P H AA L+
Sbjct: 131 AITIDGVTPLFNACSQGSPSCAELLLEYGAKA-QLESCLPSPTHEAASKGHHECLDILIS 189
Query: 472 KGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEM 651
G D + TPL++A Q LL GA + K TPLH AAQQ TE+
Sbjct: 190 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQSSTEI 248
Query: 652 CALLLEGG 675
LLLE G
Sbjct: 249 VNLLLEFG 256
Score = 64.5 bits (150), Expect = 4e-10
Identities = 46/124 (37%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Frame = +1
Query: 322 HLAAKYGNLKVANLLLA--HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
H GN K A + A +G Q +PLH AA + TLL +G + AV
Sbjct: 40 HFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAV 99
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ TPLH A + + A TLLE GA NA + G TPL A QG LLLE G
Sbjct: 100 TLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYG 159
Query: 676 PGTQ 687
Q
Sbjct: 160 AKAQ 163
>BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS
box-containing protein 16 protein.
Length = 453
Score = 97.9 bits (233), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+ +A +TD R L+R GA ++A+ R LH A D LLL GA +
Sbjct: 114 PLAIATARGYTDCARHLIRQGAELDARVGGRAA-LHEACARAQFDCVRLLLTFGAKANVL 172
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLT-ATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+ + A L+E A + A + T LH+AA G + L L H
Sbjct: 173 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEH 232
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQ--------QAVATTLLEKGADAKAVAKNGHTPLHIAA 531
GA G T L+ A + QA A LLE GADA+A + HTPLH A
Sbjct: 233 GADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNAC 292
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
A LL YGA + AG TP+ A Q
Sbjct: 293 ASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQ 326
Score = 80.2 bits (189), Expect = 7e-15
Identities = 69/208 (33%), Positives = 91/208 (43%), Gaps = 16/208 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G +H A D +R+LL GA E TPLH+ + ++ A LLL+ GA
Sbjct: 141 VGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGA 200
Query: 184 DVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK----YGNL 348
V A PLH+AA + A +EH A + T +G TAL+ A G+
Sbjct: 201 TVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSC 260
Query: 349 K----VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
+ A LL GA AG+ TPLH A +A LL GA A+ GHTP
Sbjct: 261 RRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTP 320
Query: 517 LHIAARKNQ-------METAATLLEYGA 579
+ A + Q A LL+YGA
Sbjct: 321 MDCALQAVQDAPNWEPEVLFAALLDYGA 348
Score = 79.4 bits (187), Expect = 1e-14
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 10/201 (4%)
Frame = +1
Query: 103 RERQT-PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
+ +QT PL IA+ G D A L++ GA++ A LH A + D L+
Sbjct: 108 KTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRA-ALHEACARAQFDCVRLLLTFG 166
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVA 456
A T++G T LHL +L+ A LLL GA + AG++ TPLH+AA +
Sbjct: 167 AKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHV 226
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAAR--------KNQMETAATLLEYGALTNAESKAGFT 612
LE GAD G T L+ A + A LLE GA A + T
Sbjct: 227 ALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHT 286
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A G + LLL G
Sbjct: 287 PLHNACASGCGGLAELLLRYG 307
Score = 71.7 bits (168), Expect = 2e-12
Identities = 56/159 (35%), Positives = 70/159 (44%), Gaps = 9/159 (5%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQH 177
T G TP+HL ++LL GA V A E Q TPLH+A+ G L L+H
Sbjct: 173 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEH 232
Query: 178 GADVRAITADHYNPLHIA-------AKQHNHDVAA-ALIEHNAPLTATTKKGFTALHLAA 333
GADV T+ L+ A H AA L+E A A +K T LH A
Sbjct: 233 GADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNAC 292
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQA 450
G +A LLL +GA + G TP+ A Q Q A
Sbjct: 293 ASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQDA 331
Score = 47.2 bits (107), Expect = 6e-05
Identities = 31/93 (33%), Positives = 40/93 (43%)
Frame = +1
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL IA A L+ +GA+ A G LH A + Q + LL +GA N
Sbjct: 114 PLAIATARGYTDCARHLIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVL 172
Query: 595 SKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
++ G TPLHL + LLLE G A
Sbjct: 173 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLA 205
>AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens
cDNA FLJ30165 fis, clone BRACE2000698, weakly similar to
ANKYRIN 2. ).
Length = 453
Score = 97.9 bits (233), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+ +A +TD R L+R GA ++A+ R LH A D LLL GA +
Sbjct: 114 PLAIATARGYTDCARHLIRQGAELDARVGGRAA-LHEACARAQFDCVRLLLTFGAKANVL 172
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLT-ATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+ + A L+E A + A + T LH+AA G + L L H
Sbjct: 173 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEH 232
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQ--------QAVATTLLEKGADAKAVAKNGHTPLHIAA 531
GA G T L+ A + QA A LLE GADA+A + HTPLH A
Sbjct: 233 GADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNAC 292
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
A LL YGA + AG TP+ A Q
Sbjct: 293 ASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQ 326
Score = 80.2 bits (189), Expect = 7e-15
Identities = 69/208 (33%), Positives = 91/208 (43%), Gaps = 16/208 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G +H A D +R+LL GA E TPLH+ + ++ A LLL+ GA
Sbjct: 141 VGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGA 200
Query: 184 DVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK----YGNL 348
V A PLH+AA + A +EH A + T +G TAL+ A G+
Sbjct: 201 TVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSC 260
Query: 349 K----VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
+ A LL GA AG+ TPLH A +A LL GA A+ GHTP
Sbjct: 261 RRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTP 320
Query: 517 LHIAARKNQ-------METAATLLEYGA 579
+ A + Q A LL+YGA
Sbjct: 321 MDCALQAVQDAPNWEPEVLFAALLDYGA 348
Score = 79.4 bits (187), Expect = 1e-14
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 10/201 (4%)
Frame = +1
Query: 103 RERQT-PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
+ +QT PL IA+ G D A L++ GA++ A LH A + D L+
Sbjct: 108 KTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRA-ALHEACARAQFDCVRLLLTFG 166
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVA 456
A T++G T LHL +L+ A LLL GA + AG++ TPLH+AA +
Sbjct: 167 AKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHV 226
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAAR--------KNQMETAATLLEYGALTNAESKAGFT 612
LE GAD G T L+ A + A LLE GA A + T
Sbjct: 227 ALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHT 286
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A G + LLL G
Sbjct: 287 PLHNACASGCGGLAELLLRYG 307
Score = 71.7 bits (168), Expect = 2e-12
Identities = 56/159 (35%), Positives = 70/159 (44%), Gaps = 9/159 (5%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQH 177
T G TP+HL ++LL GA V A E Q TPLH+A+ G L L+H
Sbjct: 173 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEH 232
Query: 178 GADVRAITADHYNPLHIA-------AKQHNHDVAA-ALIEHNAPLTATTKKGFTALHLAA 333
GADV T+ L+ A H AA L+E A A +K T LH A
Sbjct: 233 GADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNAC 292
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQA 450
G +A LLL +GA + G TP+ A Q Q A
Sbjct: 293 ASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQDA 331
Score = 47.2 bits (107), Expect = 6e-05
Identities = 31/93 (33%), Positives = 40/93 (43%)
Frame = +1
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL IA A L+ +GA+ A G LH A + Q + LL +GA N
Sbjct: 114 PLAIATARGYTDCARHLIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVL 172
Query: 595 SKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
++ G TPLHL + LLLE G A
Sbjct: 173 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLA 205
>AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protein 1
protein.
Length = 1431
Score = 97.9 bits (233), Expect = 3e-20
Identities = 72/238 (30%), Positives = 112/238 (47%), Gaps = 12/238 (5%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G + +H AA +T++I +LL AAV+ K + PLH A+ G + L+L+ G+ V
Sbjct: 49 GFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAV 108
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ + + PLH+AA+ ++DV+ L++H + G T L LA ++G + V LLL
Sbjct: 109 NIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLL 168
Query: 370 AHGAAP--------DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHI 525
+ D NG +PLH+AA+ + LL+ G D K+G T LH
Sbjct: 169 SSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHE 227
Query: 526 AARKNQMETAATLLEYGA---LTNAESKAGFTPLH-LAAQQGHTEMCALLLEGGPGTQ 687
AA + E LL+ G + N S+ +H Q E+ LL E Q
Sbjct: 228 AALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQ 285
Score = 80.6 bits (190), Expect = 5e-15
Identities = 56/181 (30%), Positives = 89/181 (49%), Gaps = 8/181 (4%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G P+H AA + ++++L+ G+AV + E PLH+A++ G+ D++ +LLQH ++
Sbjct: 81 KGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSN 140
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHN--------APLTATTKKGFTALHLAAKYG 342
+ PL +A + V L+ N P AT G + LHLAAK G
Sbjct: 141 PCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNG 200
Query: 343 NLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLH 522
++ + LLL G ++ K+G T LH AA + V LL+ G +A T L
Sbjct: 201 HIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTALD 259
Query: 523 I 525
I
Sbjct: 260 I 260
Score = 80.2 bits (189), Expect = 7e-15
Identities = 52/165 (31%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Frame = +1
Query: 205 DHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAA 384
D ++ LH AA N ++ + L+E A + KG LH AA G + L+L G+A
Sbjct: 48 DGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA 107
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
+ G PLH+AAQ+ V+ LL+ ++ V +G TPL +A ++ L
Sbjct: 108 VNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167
Query: 565 LEYGALT--------NAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L +A G +PLHLAA+ GH ++ LLL+ G
Sbjct: 168 LSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAG 212
Score = 30.7 bits (66), Expect = 5.7
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +1
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLE 669
N + GF+ LH AA G+TE+ +LLLE
Sbjct: 43 NFQDPDGFSALHHAALNGNTELISLLLE 70
>AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat
domain-containing SOCS box protein Asb-16 protein.
Length = 253
Score = 97.9 bits (233), Expect = 3e-20
Identities = 73/214 (34%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+ +A +TD R L+R GA ++A+ R LH A D LLL GA +
Sbjct: 13 PLAIATARGYTDCARHLIRQGAELDARVGGRAA-LHEACARAQFDCVRLLLTFGAKANVL 71
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLT-ATTKKGFTALHLAAKYGNLKVANLLLAH 375
T + PLH+ + A L+E A + A + T LH+AA G + L L H
Sbjct: 72 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEH 131
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQ--------QAVATTLLEKGADAKAVAKNGHTPLHIAA 531
GA G T L+ A + QA A LLE GADA+A + HTPLH A
Sbjct: 132 GADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNAC 191
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQ 633
A LL YGA + AG TP+ A Q
Sbjct: 192 ASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQ 225
Score = 80.2 bits (189), Expect = 7e-15
Identities = 69/208 (33%), Positives = 91/208 (43%), Gaps = 16/208 (7%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G +H A D +R+LL GA E TPLH+ + ++ A LLL+ GA
Sbjct: 40 VGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGA 99
Query: 184 DVR-AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAK----YGNL 348
V A PLH+AA + A +EH A + T +G TAL+ A G+
Sbjct: 100 TVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSC 159
Query: 349 K----VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTP 516
+ A LL GA AG+ TPLH A +A LL GA A+ GHTP
Sbjct: 160 RRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTP 219
Query: 517 LHIAARKNQ-------METAATLLEYGA 579
+ A + Q A LL+YGA
Sbjct: 220 MDCALQAVQDAPNWEPEVLFAALLDYGA 247
Score = 79.4 bits (187), Expect = 1e-14
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 10/201 (4%)
Frame = +1
Query: 103 RERQT-PLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHN 279
+ +QT PL IA+ G D A L++ GA++ A LH A + D L+
Sbjct: 7 KTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRA-ALHEACARAQFDCVRLLLTFG 65
Query: 280 APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD-QAGKNGMTPLHIAAQYDQQAVA 456
A T++G T LHL +L+ A LLL GA + AG++ TPLH+AA +
Sbjct: 66 AKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHV 125
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAAR--------KNQMETAATLLEYGALTNAESKAGFT 612
LE GAD G T L+ A + A LLE GA A + T
Sbjct: 126 ALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHT 185
Query: 613 PLHLAAQQGHTEMCALLLEGG 675
PLH A G + LLL G
Sbjct: 186 PLHNACASGCGGLAELLLRYG 206
Score = 71.7 bits (168), Expect = 2e-12
Identities = 56/159 (35%), Positives = 70/159 (44%), Gaps = 9/159 (5%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQ-TPLHIASRLGNVDIAVLLLQH 177
T G TP+HL ++LL GA V A E Q TPLH+A+ G L L+H
Sbjct: 72 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEH 131
Query: 178 GADVRAITADHYNPLHIA-------AKQHNHDVAA-ALIEHNAPLTATTKKGFTALHLAA 333
GADV T+ L+ A H AA L+E A A +K T LH A
Sbjct: 132 GADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNAC 191
Query: 334 KYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQA 450
G +A LLL +GA + G TP+ A Q Q A
Sbjct: 192 ASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQDA 230
Score = 47.2 bits (107), Expect = 6e-05
Identities = 31/93 (33%), Positives = 40/93 (43%)
Frame = +1
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
PL IA A L+ +GA+ A G LH A + Q + LL +GA N
Sbjct: 13 PLAIATARGYTDCARHLIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVL 71
Query: 595 SKAGFTPLHLAAQQGHTEMCALLLEGGPGTQFA 693
++ G TPLHL + LLLE G A
Sbjct: 72 TEEGTTPLHLCTIPESLQCAKLLLEAGATVNLA 104
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 97.1 bits (231), Expect = 6e-20
Identities = 58/197 (29%), Positives = 91/197 (46%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T H AA D + L+ +G K +E T LH+A+ G++ + L+ G D+
Sbjct: 68 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 127
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ LH AA + D L+ + + A T+K + LH AA G+ V+ +L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
G + G +PLH+A +++ A+ L+ +D AV TPLH+AA +
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 247
Query: 550 TAATLLEYGALTNAESK 600
A LL G N K
Sbjct: 248 IADMLLIAGVDLNLRDK 264
Score = 90.6 bits (215), Expect = 5e-18
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 2/224 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN--GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
G T +H AA+ H ++ ++ + A++ + +T H A+ G +D L+ G
Sbjct: 33 GLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGC 92
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
D + LH+AA + + V L++ L +G TALH AA + L
Sbjct: 93 DHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQL 152
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL G+ + + ++ LH AA + V+ L+ G A V G +PLH+A R N
Sbjct: 153 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 212
Query: 544 METAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ + NA TPLHLAA+ ++ +LL G
Sbjct: 213 PALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 256
Score = 65.7 bits (153), Expect = 2e-10
Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA- 492
AL L+A +G+L++ +L+ GA K+G+T LH AAQ V ++E D
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 493 -VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
V K G T H AA Q++ L+ G N + K G T LHLAA +GH + L++
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Query: 670 GG 675
G
Sbjct: 123 IG 124
Score = 53.2 bits (122), Expect = 9e-07
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G +P+HLA R N ++R+L+ + + V A +QTPLH+A+ DIA +LL G D
Sbjct: 199 QGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 187 VRAITADH 210
+ DH
Sbjct: 259 LNLRDKDH 266
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1679 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1738
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1739 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1798
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1799 AGLAPADVAHQRNHWDLLTLLEGAGP 1824
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1634 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1694 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1753
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1754 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1813
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1814 D-LLTLLEGAGPPEARHKA 1831
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1757
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1758 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1817
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1818 LL--EGAGPPEA-RHKATP 1833
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1615 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1674
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1675 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1734
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1735 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1794
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1795 AGLAPADVAHQRNHWDLLTLLEGAGP 1820
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1630 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1689
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1690 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1749
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1750 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1809
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1810 D-LLTLLEGAGPPEARHKA 1827
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1694 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1753
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1754 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1813
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1814 LL--EGAGPPEA-RHKATP 1829
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein protein.
Length = 1095
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 711 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 770
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 771 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 830
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 831 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 890
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 891 AGLAPADVAHQRNHWDLLTLLEGAGP 916
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 726 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 785
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 786 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 845
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 846 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 905
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 906 D-LLTLLEGAGPPEARHKA 923
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 790 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 849
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 850 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 909
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 910 LL--EGAGPPEA-RHKATP 925
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1679 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1738
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1739 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1798
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1799 AGLAPADVAHQRNHWDLLTLLEGAGP 1824
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1634 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1694 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1753
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1754 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1813
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1814 D-LLTLLEGAGPPEARHKA 1831
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1757
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1758 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1817
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1818 LL--EGAGPPEA-RHKATP 1833
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1679 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1738
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1739 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1798
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1799 AGLAPADVAHQRNHWDLLTLLEGAGP 1824
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1634 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1694 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1753
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1754 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1813
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1814 D-LLTLLEGAGPPEARHKA 1831
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1757
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1758 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1817
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1818 LL--EGAGPPEA-RHKATP 1833
>BC051904-1|AAH51904.1| 752|Homo sapiens phospholipase A2, group VI
(cytosolic, calcium-independent) protein.
Length = 752
Score = 96.3 bits (229), Expect = 1e-19
Identities = 64/214 (29%), Positives = 109/214 (50%), Gaps = 3/214 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA-VEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+GET H A + +++ ++++L RN A + + TPLH+A +LG ++ +LL A
Sbjct: 185 KGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNA 244
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPL--TATTKKGFTALHLAAKYGNLKVA 357
+ + Y P+H A K A +I ++ + + G + LH A N ++A
Sbjct: 245 RCNIMGPNGY-PIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMA 300
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + G T LH+A ++ A LL GA+A A ++G+TPLH+A K
Sbjct: 301 RMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSK 360
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQG 639
+ +E L+ +GA + + G TP LA++ G
Sbjct: 361 DNVEMIKALIVFGAEVDTPNDFGETPTFLASKIG 394
Score = 85.8 bits (203), Expect = 1e-16
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 4/226 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-A 183
G TP+HLA R +I+ L++ ++ + +T H A + N + LL ++ A
Sbjct: 152 GCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVA 211
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLH+A + ++ L+ NA G+ +H A K+ A +
Sbjct: 212 GLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGYP-IHSAMKFSQKGCAEM 270
Query: 364 LLAHGAAP--DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+++ ++ + + G +PLH A + +A LL++G + + + G+T LH+A +
Sbjct: 271 IISMDSSQIHSKDPRYGASPLHWAKNAE---MARMLLKRGCNVNSTSSAGNTALHVAVMR 327
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N+ + A LL +GA +A + G TPLHLA + + EM L+ G
Sbjct: 328 NRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVFG 373
Score = 75.4 bits (177), Expect = 2e-13
Identities = 61/198 (30%), Positives = 93/198 (46%), Gaps = 4/198 (2%)
Frame = +1
Query: 94 AKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIE 273
A+ E TPLH+A R G+ +I V L+Q+ +T + A Q ++ L+
Sbjct: 147 AENEEGCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLG 206
Query: 274 HN--APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQ 447
N A L +G T LHLA + G ++ +LL A + G NG P+H A ++ Q+
Sbjct: 207 RNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGY-PIHSAMKFSQK 265
Query: 448 AVATTLLEKGADA--KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
A ++ + + G +PLH A KN E A LL+ G N+ S AG T LH
Sbjct: 266 GCAEMIISMDSSQIHSKDPRYGASPLHWA--KN-AEMARMLLKRGCNVNSTSSAGNTALH 322
Query: 622 LAAQQGHTEMCALLLEGG 675
+A + + +LL G
Sbjct: 323 VAVMRNRFDCAIVLLTHG 340
Score = 64.1 bits (149), Expect = 5e-10
Identities = 40/145 (27%), Positives = 72/145 (49%), Gaps = 2/145 (1%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLR-NGAAVEAK-ARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
P+H A + + +++ + + + +K R +PLH A N ++A +LL+ G +V
Sbjct: 255 PIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCNVN 311
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ ++ LH+A ++ D A L+ H A A + G T LHLA N+++ L+
Sbjct: 312 STSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIV 371
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
GA D G TP +A++ +Q
Sbjct: 372 FGAEVDTPNDFGETPTFLASKIGRQ 396
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1679 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1738
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1739 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1798
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1799 AGLAPADVAHQRNHWDLLTLLEGAGP 1824
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1634 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1694 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1753
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1754 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1813
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1814 D-LLTLLEGAGPPEARHKA 1831
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1757
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1758 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1817
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1818 LL--EGAGPPEA-RHKATP 1833
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1679 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1738
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1739 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1798
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1799 AGLAPADVAHQRNHWDLLTLLEGAGP 1824
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1634 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1694 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1753
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1754 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1813
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1814 D-LLTLLEGAGPPEARHKA 1831
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1757
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1758 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1817
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1818 LL--EGAGPPEA-RHKATP 1833
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1679 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1738
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1739 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1798
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1799 AGLAPADVAHQRNHWDLLTLLEGAGP 1824
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1634 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1693
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1694 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1753
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1754 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1813
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1814 D-LLTLLEGAGPPEARHKA 1831
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1757
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1758 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1817
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1818 LL--EGAGPPEA-RHKATP 1833
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/206 (33%), Positives = 93/206 (45%), Gaps = 2/206 (0%)
Frame = +1
Query: 67 LLRNGAAVEAKA-RERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQH 243
LL GA +A +TPLH+A+R A LL+ GA+ PLH A
Sbjct: 1621 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1680
Query: 244 NHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPL 420
+V L+ + A T+ G T L LAA+ + L+A A K G T L
Sbjct: 1681 AREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTAL 1740
Query: 421 HIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESK 600
H AA + A +LL+ GAD A TPL +AAR+ +E A LL GA +
Sbjct: 1741 HWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQ 1800
Query: 601 AGFTPLHLAAQQGHTEMCALLLEGGP 678
AG P +A Q+ H ++ LL GP
Sbjct: 1801 AGLAPADVAHQRNHWDLLTLLEGAGP 1826
Score = 95.5 bits (227), Expect = 2e-19
Identities = 73/199 (36%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQ-HGAD 186
GETP+HLAAR + R LL GA R +TPLH A ++ LLL+
Sbjct: 1636 GETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTA 1695
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V A T D PL +AA+ D+ LI A + A K G TALH AA N + A L
Sbjct: 1696 VDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSL 1755
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L GA D TPL +AA+ VA LL GA + + G P +A ++N
Sbjct: 1756 LQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHW 1815
Query: 547 ETAATLLEYGALTNAESKA 603
+ TLLE A KA
Sbjct: 1816 D-LLTLLEGAGPPEARHKA 1833
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/139 (31%), Positives = 66/139 (47%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G TP+ LAAR D++ L+ A V A+ + +T LH A+ + N A LLQ G
Sbjct: 1700 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAG 1759
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
AD A PL +AA++ +VA L+ A + G +A + + +
Sbjct: 1760 ADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLT 1819
Query: 361 LLLAHGAAPDQAGKNGMTP 417
LL GA P +A ++ TP
Sbjct: 1820 LL--EGAGPPEA-RHKATP 1835
>AF102988-1|AAD41722.1| 752|Homo sapiens Ca2+-independent
phospholipase A2 short isoform protein.
Length = 752
Score = 96.3 bits (229), Expect = 1e-19
Identities = 64/214 (29%), Positives = 109/214 (50%), Gaps = 3/214 (1%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAA-VEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
+GET H A + +++ ++++L RN A + + TPLH+A +LG ++ +LL A
Sbjct: 185 KGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNA 244
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPL--TATTKKGFTALHLAAKYGNLKVA 357
+ + Y P+H A K A +I ++ + + G + LH A N ++A
Sbjct: 245 RCNIMGPNGY-PIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMA 300
Query: 358 NLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+LL G + G T LH+A ++ A LL GA+A A ++G+TPLH+A K
Sbjct: 301 RMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSK 360
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQG 639
+ +E L+ +GA + + G TP LA++ G
Sbjct: 361 DNVEMIKALIVFGAEVDTPNDFGETPTFLASKIG 394
Score = 85.8 bits (203), Expect = 1e-16
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 4/226 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-A 183
G TP+HLA R +I+ L++ ++ + +T H A + N + LL ++ A
Sbjct: 152 GCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVA 211
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ + PLH+A + ++ L+ NA G+ +H A K+ A +
Sbjct: 212 GLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGYP-IHSAMKFSQKGCAEM 270
Query: 364 LLAHGAAP--DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARK 537
+++ ++ + + G +PLH A + +A LL++G + + + G+T LH+A +
Sbjct: 271 IISMDSSQIHSKDPRYGASPLHWAKNAE---MARMLLKRGCNVNSTSSAGNTALHVAVMR 327
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
N+ + A LL +GA +A + G TPLHLA + + EM L+ G
Sbjct: 328 NRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVFG 373
Score = 75.4 bits (177), Expect = 2e-13
Identities = 61/198 (30%), Positives = 93/198 (46%), Gaps = 4/198 (2%)
Frame = +1
Query: 94 AKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIE 273
A+ E TPLH+A R G+ +I V L+Q+ +T + A Q ++ L+
Sbjct: 147 AENEEGCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLG 206
Query: 274 HN--APLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQ 447
N A L +G T LHLA + G ++ +LL A + G NG P+H A ++ Q+
Sbjct: 207 RNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGY-PIHSAMKFSQK 265
Query: 448 AVATTLLEKGADA--KAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLH 621
A ++ + + G +PLH A KN E A LL+ G N+ S AG T LH
Sbjct: 266 GCAEMIISMDSSQIHSKDPRYGASPLHWA--KN-AEMARMLLKRGCNVNSTSSAGNTALH 322
Query: 622 LAAQQGHTEMCALLLEGG 675
+A + + +LL G
Sbjct: 323 VAVMRNRFDCAIVLLTHG 340
Score = 64.1 bits (149), Expect = 5e-10
Identities = 40/145 (27%), Positives = 72/145 (49%), Gaps = 2/145 (1%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLR-NGAAVEAK-ARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
P+H A + + +++ + + + +K R +PLH A N ++A +LL+ G +V
Sbjct: 255 PIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCNVN 311
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ ++ LH+A ++ D A L+ H A A + G T LHLA N+++ L+
Sbjct: 312 STSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIV 371
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQ 447
GA D G TP +A++ +Q
Sbjct: 372 FGAEVDTPNDFGETPTFLASKIGRQ 396
>BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/220 (30%), Positives = 104/220 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H N +I+++LL +GA V AK E TPLH A+ G++++ +L+Q+GAD+
Sbjct: 101 GLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL 160
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +D P + + DV IE T++ + +A + + + ++
Sbjct: 161 LAVNSDGNMPYDLCEDEPTLDV----IETCMAYQGITQEKINEMRVAPEQQMIADIHCMI 216
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G D G T LHIA A LL+ G +G PLH AA QM+
Sbjct: 217 AAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQ 276
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A L+ +GA +A + P+ L ++ E LLLE
Sbjct: 277 MAELLVSHGASLSARTSMDEMPIDLCEEE---EFKVLLLE 313
Score = 78.2 bits (184), Expect = 3e-14
Identities = 56/215 (26%), Positives = 91/215 (42%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A+ N + +R L+N + + + T LH +I LLL HGA+V A +
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
+ PLH AA + ++ L+++ A L A G L L V +A+
Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQ 194
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
+ + + +A + A ++ G D + G T LHIA + A LL+
Sbjct: 195 EK----INEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLD 250
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+G + + G+ PLH AA G +M LL+ G
Sbjct: 251 HGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHG 285
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G T +H+A + +LL +G V+ K + PLH A+ G + +A LL+ HGA
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 187 VRAITADHYNPLHIAAKQ----------HNHDV-AAALIEHNAPLTATT 300
+ A T+ P+ + ++ H HDV + + H + L+ T
Sbjct: 288 LSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSRRT 336
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/107 (27%), Positives = 46/107 (42%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
AL A+ + + L + +PD ++G+T LH + + + LL GA+ A
Sbjct: 71 ALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAK 130
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
TPLH AA + L++YGA A + G P L +
Sbjct: 131 DNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDE 177
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/155 (21%), Positives = 62/155 (40%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P L D+I + A + +E+ + +A + ++ G D+
Sbjct: 167 GNMPYDLCEDEPTLDVIETCM----AYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDL 222
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I A LHIA A L++H + G+ LH AA +G +++A LL+
Sbjct: 223 DWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLV 282
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
+HGA+ P+ + + + + + L K
Sbjct: 283 SHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHK 317
>BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 16
protein.
Length = 361
Score = 95.9 bits (228), Expect = 1e-19
Identities = 72/223 (32%), Positives = 103/223 (46%), Gaps = 4/223 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G+T +H AAR H D++ L G +EA R+ + PLH A+ +G+ D LL GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN-LKVANL 363
V + + PL +A + N V L+EH A K G+ + H+A++ G+ L + L
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYL 156
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKN-GHTPLHIAARKN 540
L A K TPLH AA + LL++ N G T L A +
Sbjct: 157 LTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCG 216
Query: 541 QMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
++ A LL E+GA +AE G LH AA G E L+
Sbjct: 217 HIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLV 259
Score = 80.2 bits (189), Expect = 7e-15
Identities = 71/226 (31%), Positives = 100/226 (44%), Gaps = 6/226 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV-R 192
TP+ +A + +I+ L+ +GA K ++ HIASR G+ I LL +
Sbjct: 106 TPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWK 165
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK--GFTALHLAAKYGNLKVANLL 366
+ PLH AA H H A ++ + G TAL A + G++ VA LL
Sbjct: 166 TESKIRRTPLHTAA-MHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLL 224
Query: 367 L-AHGAAPDQAGKNGMTPLHIAAQYDQ-QAVATTLLEKGADAKAVAKNGH-TPLHIAARK 537
L HGA G LH AA Q +A+ + E G D A + H T LH AA++
Sbjct: 225 LDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKE 284
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T TLL GA N++ + + LHLA H LL+ G
Sbjct: 285 GHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG 330
Score = 58.4 bits (135), Expect = 2e-08
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = +1
Query: 307 GFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
G T LH AA++G+ V A L A G + ++ PLH AA + LL +GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ K TPL +A + + L+E+GA ++K G+ H+A+++G + L
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYL 156
Query: 664 LEGGPG 681
L PG
Sbjct: 157 LTVCPG 162
>AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 16
protein.
Length = 361
Score = 95.9 bits (228), Expect = 1e-19
Identities = 72/223 (32%), Positives = 103/223 (46%), Gaps = 4/223 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G+T +H AAR H D++ L G +EA R+ + PLH A+ +G+ D LL GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN-LKVANL 363
V + + PL +A + N V L+EH A K G+ + H+A++ G+ L + L
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYL 156
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKN-GHTPLHIAARKN 540
L A K TPLH AA + LL++ N G T L A +
Sbjct: 157 LTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCG 216
Query: 541 QMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
++ A LL E+GA +AE G LH AA G E L+
Sbjct: 217 HIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLV 259
Score = 80.2 bits (189), Expect = 7e-15
Identities = 71/226 (31%), Positives = 100/226 (44%), Gaps = 6/226 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV-R 192
TP+ +A + +I+ L+ +GA K ++ HIASR G+ I LL +
Sbjct: 106 TPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWK 165
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKK--GFTALHLAAKYGNLKVANLL 366
+ PLH AA H H A ++ + G TAL A + G++ VA LL
Sbjct: 166 TESKIRRTPLHTAA-MHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLL 224
Query: 367 L-AHGAAPDQAGKNGMTPLHIAAQYDQ-QAVATTLLEKGADAKAVAKNGH-TPLHIAARK 537
L HGA G LH AA Q +A+ + E G D A + H T LH AA++
Sbjct: 225 LDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKE 284
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
T TLL GA N++ + + LHLA H LL+ G
Sbjct: 285 GHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG 330
Score = 58.4 bits (135), Expect = 2e-08
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Frame = +1
Query: 307 GFTALHLAAKYGNLKV-ANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGAD 483
G T LH AA++G+ V A L A G + ++ PLH AA + LL +GA
Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAA 96
Query: 484 AKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ K TPL +A + + L+E+GA ++K G+ H+A+++G + L
Sbjct: 97 VDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYL 156
Query: 664 LEGGPG 681
L PG
Sbjct: 157 LTVCPG 162
>AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/220 (30%), Positives = 104/220 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H N +I+++LL +GA V AK E TPLH A+ G++++ +L+Q+GAD+
Sbjct: 101 GLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL 160
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +D P + + DV IE T++ + +A + + + ++
Sbjct: 161 LAVNSDGNMPYDLCEDEPTLDV----IETCMAYQGITQEKINEMRVAPEQQMIADIHCMI 216
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G D G T LHIA A LL+ G +G PLH AA QM+
Sbjct: 217 AAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQ 276
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A L+ +GA +A + P+ L ++ E LLLE
Sbjct: 277 MAELLVSHGASLSARTSMDEMPIDLCEEE---EFKVLLLE 313
Score = 78.2 bits (184), Expect = 3e-14
Identities = 56/215 (26%), Positives = 91/215 (42%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A+ N + +R L+N + + + T LH +I LLL HGA+V A +
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
+ PLH AA + ++ L+++ A L A G L L V +A+
Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQ 194
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
+ + + +A + A ++ G D + G T LHIA + A LL+
Sbjct: 195 EK----INEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLD 250
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+G + + G+ PLH AA G +M LL+ G
Sbjct: 251 HGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHG 285
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G T +H+A + +LL +G V+ K + PLH A+ G + +A LL+ HGA
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 187 VRAITADHYNPLHIAAKQ----------HNHDV-AAALIEHNAPLTATT 300
+ A T+ P+ + ++ H HDV + + H + L+ T
Sbjct: 288 LSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSRRT 336
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/107 (27%), Positives = 46/107 (42%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
AL A+ + + L + +PD ++G+T LH + + + LL GA+ A
Sbjct: 71 ALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAK 130
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
TPLH AA + L++YGA A + G P L +
Sbjct: 131 DNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDE 177
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/155 (21%), Positives = 62/155 (40%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P L D+I + A + +E+ + +A + ++ G D+
Sbjct: 167 GNMPYDLCEDEPTLDVIETCM----AYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDL 222
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I A LHIA A L++H + G+ LH AA +G +++A LL+
Sbjct: 223 DWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLV 282
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
+HGA+ P+ + + + + + L K
Sbjct: 283 SHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHK 317
>AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/220 (30%), Positives = 104/220 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H N +I+++LL +GA V AK E TPLH A+ G++++ +L+Q+GAD+
Sbjct: 101 GLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL 160
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +D P + + DV IE T++ + +A + + + ++
Sbjct: 161 LAVNSDGNMPYDLCEDEPTLDV----IETCMAYQGITQEKINEMRVAPEQQMIADIHCMI 216
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G D G T LHIA A LL+ G +G PLH AA QM+
Sbjct: 217 AAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQ 276
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A L+ +GA +A + P+ L ++ E LLLE
Sbjct: 277 MAELLVSHGASLSARTSMDEMPIDLCEEE---EFKVLLLE 313
Score = 78.2 bits (184), Expect = 3e-14
Identities = 56/215 (26%), Positives = 91/215 (42%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A+ N + +R L+N + + + T LH +I LLL HGA+V A +
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
+ PLH AA + ++ L+++ A L A G L L V +A+
Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQ 194
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
+ + + +A + A ++ G D + G T LHIA + A LL+
Sbjct: 195 EK----INEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLD 250
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+G + + G+ PLH AA G +M LL+ G
Sbjct: 251 HGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHG 285
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G T +H+A + +LL +G V+ K + PLH A+ G + +A LL+ HGA
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 187 VRAITADHYNPLHIAAKQ----------HNHDV-AAALIEHNAPLTATT 300
+ A T+ P+ + ++ H HDV + + H + L+ T
Sbjct: 288 LSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSRRT 336
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/107 (27%), Positives = 46/107 (42%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
AL A+ + + L + +PD ++G+T LH + + + LL GA+ A
Sbjct: 71 ALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAK 130
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
TPLH AA + L++YGA A + G P L +
Sbjct: 131 DNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDE 177
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/155 (21%), Positives = 62/155 (40%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P L D+I + A + +E+ + +A + ++ G D+
Sbjct: 167 GNMPYDLCEDEPTLDVIETCM----AYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDL 222
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I A LHIA A L++H + G+ LH AA +G +++A LL+
Sbjct: 223 DWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLV 282
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
+HGA+ P+ + + + + + L K
Sbjct: 283 SHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHK 317
>AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP
protein.
Length = 567
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/220 (30%), Positives = 104/220 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H N +I+++LL +GA V AK E TPLH A+ G++++ +L+Q+GAD+
Sbjct: 101 GLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL 160
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +D P + + DV IE T++ + +A + + + ++
Sbjct: 161 LAVNSDGNMPYDLCEDEPTLDV----IETCMAYQGITQEKINEMRVAPEQQMIADIHCMI 216
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G D G T LHIA A LL+ G +G PLH AA QM+
Sbjct: 217 AAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQ 276
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A L+ +GA +A + P+ L ++ E LLLE
Sbjct: 277 MAELLVSHGASLSARTSMDEMPIDLCEEE---EFKVLLLE 313
Score = 78.2 bits (184), Expect = 3e-14
Identities = 56/215 (26%), Positives = 91/215 (42%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A+ N + +R L+N + + + T LH +I LLL HGA+V A +
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 134
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
+ PLH AA + ++ L+++ A L A G L L V +A+
Sbjct: 135 WTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQ 194
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
+ + + +A + A ++ G D + G T LHIA + A LL+
Sbjct: 195 EK----INEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLD 250
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+G + + G+ PLH AA G +M LL+ G
Sbjct: 251 HGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHG 285
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G T +H+A + +LL +G V+ K + PLH A+ G + +A LL+ HGA
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 187 VRAITADHYNPLHIAAKQ----------HNHDV-AAALIEHNAPLTATT 300
+ A T+ P+ + ++ H HDV + + H + L+ T
Sbjct: 288 LSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSRRT 336
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/107 (27%), Positives = 46/107 (42%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
AL A+ + + L + +PD ++G+T LH + + + LL GA+ A
Sbjct: 71 ALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAK 130
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
TPLH AA + L++YGA A + G P L +
Sbjct: 131 DNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDE 177
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/155 (21%), Positives = 62/155 (40%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P L D+I + A + +E+ + +A + ++ G D+
Sbjct: 167 GNMPYDLCEDEPTLDVIETCM----AYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDL 222
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I A LHIA A L++H + G+ LH AA +G +++A LL+
Sbjct: 223 DWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLV 282
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
+HGA+ P+ + + + + + L K
Sbjct: 283 SHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHK 317
>AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein.
Length = 578
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/220 (30%), Positives = 104/220 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H N +I+++LL +GA V AK E TPLH A+ G++++ +L+Q+GAD+
Sbjct: 112 GLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL 171
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +D P + + DV IE T++ + +A + + + ++
Sbjct: 172 LAVNSDGNMPYDLCEDEPTLDV----IETCMAYQGITQEKINEMRVAPEQQMIADIHCMI 227
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A G D G T LHIA A LL+ G +G PLH AA QM+
Sbjct: 228 AAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQ 287
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A L+ +GA +A + P+ L ++ E LLLE
Sbjct: 288 MAELLVSHGASLSARTSMDEMPIDLCEEE---EFKVLLLE 324
Score = 78.2 bits (184), Expect = 3e-14
Identities = 56/215 (26%), Positives = 91/215 (42%)
Frame = +1
Query: 31 AARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADH 210
A+ N + +R L+N + + + T LH +I LLL HGA+V A +
Sbjct: 86 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNEL 145
Query: 211 YNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPD 390
+ PLH AA + ++ L+++ A L A G L L V +A+
Sbjct: 146 WTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQ 205
Query: 391 QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLE 570
+ + + +A + A ++ G D + G T LHIA + A LL+
Sbjct: 206 EK----INEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLD 261
Query: 571 YGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+G + + G+ PLH AA G +M LL+ G
Sbjct: 262 HGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHG 296
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
+G T +H+A + +LL +G V+ K + PLH A+ G + +A LL+ HGA
Sbjct: 239 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 298
Query: 187 VRAITADHYNPLHIAAKQ----------HNHDV-AAALIEHNAPLTATT 300
+ A T+ P+ + ++ H HDV + + H + L+ T
Sbjct: 299 LSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSRRT 347
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/107 (27%), Positives = 46/107 (42%)
Frame = +1
Query: 316 ALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
AL A+ + + L + +PD ++G+T LH + + + LL GA+ A
Sbjct: 82 ALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAK 141
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
TPLH AA + L++YGA A + G P L +
Sbjct: 142 DNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDE 188
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/155 (21%), Positives = 62/155 (40%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P L D+I + A + +E+ + +A + ++ G D+
Sbjct: 178 GNMPYDLCEDEPTLDVIETCM----AYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDL 233
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
I A LHIA A L++H + G+ LH AA +G +++A LL+
Sbjct: 234 DWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLV 293
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
+HGA+ P+ + + + + + L K
Sbjct: 294 SHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHK 328
>AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein
protein.
Length = 1031
Score = 95.5 bits (227), Expect = 2e-19
Identities = 61/219 (27%), Positives = 103/219 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ AAR H + ++ LL GA V+ + T L +A + G +L+ +V
Sbjct: 171 GTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNV 230
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D L IA+K+ + ++ L++ + + G T L A + G++++ LL
Sbjct: 231 NLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALL 290
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQME 549
A D G++ T L+ A + + +L+ D + K+G TPL A + +E
Sbjct: 291 QKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIE 350
Query: 550 TAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
LL+ GA +A K G TPLH+A + ++ LLL
Sbjct: 351 VVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLL 389
Score = 94.7 bits (225), Expect = 3e-19
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 1/223 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+ +AA + +I++ L++NGA + + T L AS+ G+V I LL+ G ++
Sbjct: 38 GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNL 97
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNA-PLTATTKKGFTALHLAAKYGNLKVANLL 366
+ L A + DV L+ H A P + + AA G+ + +LL
Sbjct: 98 EHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQYSVYPIIWAAGRGHADIVHLL 157
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L +GA + + K G TPL AA+ LL GAD N T L +A +
Sbjct: 158 LQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYT 217
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
++ +L+ N K G T L +A+++GHTE+ LL+ G
Sbjct: 218 QSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 260
Score = 94.3 bits (224), Expect = 4e-19
Identities = 67/219 (30%), Positives = 103/219 (47%)
Frame = +1
Query: 19 PVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
P+ AA H DI+ +LL+NGA V + TPL A+R G+++ LL GADV
Sbjct: 141 PIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQE 200
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
A+ L +A K +++ N + T K G TAL +A+K G+ ++ LL G
Sbjct: 201 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 260
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAA 558
+ ++G T L A + + LL+K AD ++ T L+ A K
Sbjct: 261 TYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVR 320
Query: 559 TLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+L+ T +K G TPL A + + E+ LLL+ G
Sbjct: 321 DILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKG 359
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/208 (31%), Positives = 99/208 (47%), Gaps = 1/208 (0%)
Frame = +1
Query: 58 IRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAK 237
++ LL V+ + QTPL IA+ GN++I L+++GA+ D++ L A+K
Sbjct: 21 LKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASK 80
Query: 238 QHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAG-KNGMT 414
+ + + L++ L G+TAL A G V LLL+HGA P G + +
Sbjct: 81 EGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQYSVY 140
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAE 594
P+ AA + LL+ GA K G TPL AARK +E LL GA + E
Sbjct: 141 PIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQE 200
Query: 595 SKAGFTPLHLAAQQGHTEMCALLLEGGP 678
T L +A + G+T+ +L+ P
Sbjct: 201 GANSMTALIVAVKGGYTQSVKEILKRNP 228
Score = 84.2 bits (199), Expect = 4e-16
Identities = 59/175 (33%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T + +A++ HT+I++ LL G V R T L A R G+V+I LLQ AD+
Sbjct: 237 GNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADI 296
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
D+ L+ A ++ N + +++ N TK G T L A K N++V LLL
Sbjct: 297 DIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLL 356
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV---AKNGHTPLHI 525
GA K G TPLHIA + + +A LL D + + K G TP +I
Sbjct: 357 DKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNI 411
Score = 73.7 bits (173), Expect = 6e-13
Identities = 60/227 (26%), Positives = 98/227 (43%), Gaps = 1/227 (0%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQT-PLHIASRLGNVDIAVLLLQHGAD 186
G T + A TD++ +LL +GA + P+ A+ G+ DI LLLQ+GA
Sbjct: 104 GWTALMWACYKGRTDVVELLLSHGANPSVTGLQYSVYPIIWAAGRGHADIVHLLLQNGAK 163
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
V PL AA++ + + L+ A + TAL +A K G + +
Sbjct: 164 VNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEI 223
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + K+G T L IA++ + LL+ G ++G T L A R +
Sbjct: 224 LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHV 283
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGPGTQ 687
E LL+ A + + T L+ A ++G+ M +L+ P T+
Sbjct: 284 EIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTE 330
Score = 67.3 bits (157), Expect = 5e-11
Identities = 54/178 (30%), Positives = 76/178 (42%), Gaps = 1/178 (0%)
Frame = +1
Query: 145 NVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALH 324
N+ LL+ DV PL IAA+Q N ++ LI++ A +TAL
Sbjct: 17 NIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALI 76
Query: 325 LAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA-K 501
A+K G++ + LL G + G T L A + V LL GA+ +
Sbjct: 77 SASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQ 136
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
P+ AA + + LL+ GA N K G TPL AA++GH E LL G
Sbjct: 137 YSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMG 194
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/66 (37%), Positives = 39/66 (59%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T GETP+ A + + +++ +LL GA V A ++ TPLHIA R + +A LLL++
Sbjct: 333 TKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNP 392
Query: 181 ADVRAI 198
D R +
Sbjct: 393 KDGRLL 398
>AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transcript
8 BAT8 isoform a variant protein.
Length = 1031
Score = 95.5 bits (227), Expect = 2e-19
Identities = 66/216 (30%), Positives = 111/216 (51%), Gaps = 9/216 (4%)
Frame = +1
Query: 55 IIRILLRN-GAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
+I +LL N ++ + ++TPLH A++ G+V+I +LLQ GA++ A+ PL A
Sbjct: 480 VILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEA 539
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQA-GKNG 408
++ +VA +++ + + + G T LH AAK GNL++ +LLL+ G A G
Sbjct: 540 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 599
Query: 409 MTPLHIAAQYDQQAVATTLLEKGAD-------AKAVAKNGHTPLHIAARKNQMETAATLL 567
TP+ AA++ V LL +GAD ++ + + + LH A+ A LL
Sbjct: 600 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEENICLHWASFTGSAAIAEVLL 659
Query: 568 EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+A + G TPLH+AA++ + + L L G
Sbjct: 660 NARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRG 695
Score = 87.0 bits (206), Expect = 6e-17
Identities = 63/215 (29%), Positives = 105/215 (48%), Gaps = 8/215 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA+ +I +LL+ GA + A ++++TPL A ++++A ++Q G V +
Sbjct: 501 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 560
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
D LH AAK N ++ + L+ + A G+T + AA++ +++V +LL
Sbjct: 561 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 620
Query: 373 HGA-------APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
GA ++ + LH A+ A+A LL D AV +G TPLHIAA
Sbjct: 621 RGADVTLTDNVSERLVEEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAA 680
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQ 636
R++ + L GA +K G T L ++
Sbjct: 681 RESYHDCVLLFLSRGANPELRNKEGDTAWDLTPER 715
Score = 74.1 bits (174), Expect = 5e-13
Identities = 53/191 (27%), Positives = 90/191 (47%), Gaps = 8/191 (4%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG-ADVR 192
TP+ A NH ++ R +++ G V +K + T LH A+++GN+++ LLL G DV
Sbjct: 534 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 593
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTAT-------TKKGFTALHLAAKYGNLK 351
A + + P+ AA+ + +V L+ A +T T ++ LH A+ G+
Sbjct: 594 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEENICLHWASFTGSAA 653
Query: 352 VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
+A +LL +G TPLHIAA+ L +GA+ + K G T +
Sbjct: 654 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTP 713
Query: 532 RKNQMETAATL 564
++ + A L
Sbjct: 714 ERSDVWFALQL 724
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/113 (35%), Positives = 52/113 (46%), Gaps = 7/113 (6%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAV-------EAKARERQTPLHIASRLGNVDIAVLL 168
G TP+ AA H ++IR+LL GA V E E LH AS G+ IA +L
Sbjct: 599 GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEENICLHWASFTGSAAIAEVL 658
Query: 169 LQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHL 327
L D+ A+ PLHIAA++ HD + A K+G TA L
Sbjct: 659 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 711
Score = 36.7 bits (81), Expect = 0.087
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLL---LQHG 180
G+TP+H+AAR ++ D + + L GA E + +E T + +V A+ L L+ G
Sbjct: 672 GDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLG 731
Query: 181 ADVRAITAD 207
RAI +
Sbjct: 732 VGNRAIRTE 740
>BC001244-1|AAH01244.1| 252|Homo sapiens ASB9 protein protein.
Length = 252
Score = 95.1 bits (226), Expect = 2e-19
Identities = 68/219 (31%), Positives = 102/219 (46%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA H +R L+ G AV + +PLH A G++ +LL+HGA V
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+TAD + PL A + D L++H A + + + +H AA+ A+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAAR----------RAY 146
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETA 555
G D + TPL++A + Q+A LLE GAD K +PLH AR E A
Sbjct: 147 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ-GKGQDSPLHAVARTASEELA 205
Query: 556 ATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
L+++GA T A++ G P+ L + L EG
Sbjct: 206 CLLMDFGADTQAKNAEGKRPVELVPPESPLAQLFLEREG 244
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/191 (31%), Positives = 89/191 (46%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTA 294
+P+H A+ G+ L+ G V ITADH +PLH A + L++H A +
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 295 TTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEK 474
T T L A G+ NLLL HGA+ Q + +P+H AA+ +A + K
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAAR---RAYGGNIDHK 153
Query: 475 GADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMC 654
++ G TPL++A Q LLE GA N + K +PLH A+ E+
Sbjct: 154 ------ISHLG-TPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASEELA 205
Query: 655 ALLLEGGPGTQ 687
LL++ G TQ
Sbjct: 206 CLLMDFGADTQ 216
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/120 (27%), Positives = 55/120 (45%)
Frame = +1
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATT 462
PL ++ +H AA +G+ L++ G A + + ++PLH A +
Sbjct: 28 PLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKI 87
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LL+ GA V + HTPL A + LL++GA ES +P+H AA++ +
Sbjct: 88 LLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRAY 146
>AB033081-1|BAA86569.2| 1232|Homo sapiens KIAA1255 protein protein.
Length = 1232
Score = 95.1 bits (226), Expect = 2e-19
Identities = 75/234 (32%), Positives = 112/234 (47%), Gaps = 10/234 (4%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQ--TPLHIASRLGNVDIA-VLLLQHG 180
G TP+H+A + H II++L+ + + R+RQ TP A N A +L +
Sbjct: 866 GRTPIHVAISSQHGVIIQLLVSH-PDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRES 924
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKG--FTALHLAAKYGN-LK 351
+ N LH+A + + + LI +A + + + T LHLA + G+ +
Sbjct: 925 GAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEII 984
Query: 352 VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
V NLLLA GA ++ K+ T LH+AAQ D + + LLE G D AV +NG+ LH+A
Sbjct: 985 VRNLLLA-GAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 1043
Query: 532 RKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCA---LLLEGGPG 681
++ LL E A + G +PLH+ Q G A L LE PG
Sbjct: 1044 MHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPG 1097
Score = 94.7 bits (225), Expect = 3e-19
Identities = 63/199 (31%), Positives = 94/199 (47%), Gaps = 4/199 (2%)
Frame = +1
Query: 91 EAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALI 270
E +AR+ QTPLH+A+ G + LL+ GA+V A A+ P+H+A + + L+
Sbjct: 827 EEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLV 886
Query: 271 EH-NAPLTATTKKGFTALHLAAKYGNLKVANLLL-AHGAAPDQAGKNGMTPLHIAAQYDQ 444
H + L ++G T A + N K A +L A +Q G LH+A Q
Sbjct: 887 SHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSD 946
Query: 445 QAVATTLLEKGADAKAVAKNGH--TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPL 618
L+ A+ + ++ TPLH+A + LL GA N +K T L
Sbjct: 947 IESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTAL 1006
Query: 619 HLAAQQGHTEMCALLLEGG 675
HLAAQQ +C++LLE G
Sbjct: 1007 HLAAQQDLPTICSVLLENG 1025
Score = 91.1 bits (216), Expect = 4e-18
Identities = 73/236 (30%), Positives = 106/236 (44%), Gaps = 16/236 (6%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
R +T + LA I LL +GAA+ + QT LH+A + + A+ LL+H AD
Sbjct: 651 RDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQAD 710
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ T D L +A + V A+ A ++ +KG L LA +A+ L
Sbjct: 711 INVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTL 770
Query: 367 LAHG--AAPDQAGKNG--MTPLHIAAQYDQQAVATTLLEKGADAKAV------------A 498
+ HG A G G T LH A + + A L+ G D + A
Sbjct: 771 VRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEA 830
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
++G TPLH+AA ET LLE+GA NA+ G TP+H+A H + LL+
Sbjct: 831 RDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLV 886
Score = 89.4 bits (212), Expect = 1e-17
Identities = 66/224 (29%), Positives = 104/224 (46%), Gaps = 5/224 (2%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G+TP+HLAA + ++ LL GA V A+ E +TP+H+A + I LL+ H D+
Sbjct: 833 GQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSH-PDI 891
Query: 190 RAITADH--YNPLHIAAKQHNHDVAAALIE-HNAPLTATTKKGFTALHLAAKYGNLK-VA 357
D P A N+ A A+++ + KG LH+A + +++ V
Sbjct: 892 HLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVL 951
Query: 358 NLLLAHGAAPDQA-GKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
L+ H + + +TPLH+A Q + + LL GA + K+ T LH+AA+
Sbjct: 952 FLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQ 1011
Query: 535 KNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
++ + LLE G A + G LHLA G +LL
Sbjct: 1012 QDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLL 1055
Score = 87.4 bits (207), Expect = 5e-17
Identities = 78/254 (30%), Positives = 112/254 (44%), Gaps = 29/254 (11%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGA-AVEA------------KARERQTPLHIASRL 141
+V +TP+H+A NH D++ ++L A A+ A K QT L +A
Sbjct: 603 SVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWT 662
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G IA LL GA + +D LH+A ++ + A L+EH A + T+ G TAL
Sbjct: 663 GMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETAL 722
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
LA + V + + GA + G PL +A + + +A+TL+ G DA
Sbjct: 723 QLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGP 782
Query: 502 NG----HTPLHIAARKNQMETAATLLEYGALTNA------------ESKAGFTPLHLAAQ 633
T LH A +N TA L+ G N+ E++ G TPLHLAA
Sbjct: 783 GPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAAS 842
Query: 634 QGHTEMCALLLEGG 675
G E LLE G
Sbjct: 843 WGLEETVQCLLEFG 856
Score = 67.3 bits (157), Expect = 5e-11
Identities = 73/257 (28%), Positives = 103/257 (40%), Gaps = 32/257 (12%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T G + AA A + L NGA V + + +TPLH A R G ++ LLQ G
Sbjct: 518 TATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQG 577
Query: 181 ADVRAIT----------------ADHYN---PLHIAAKQHNHDVAAALIEHNA-PLTATT 300
A+ T AD + PLH+A ++ DV + ++E A L AT
Sbjct: 578 ANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATN 637
Query: 301 ------------KKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQ 444
+ T L LA G +A LL GAA + +G T LH+A Q
Sbjct: 638 NLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQD 697
Query: 445 QAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHL 624
A LLE AD ++G T L +A R + GA + + G PL L
Sbjct: 698 SKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWL 757
Query: 625 AAQQGHTEMCALLLEGG 675
A ++ + L+ G
Sbjct: 758 ALANNLEDIASTLVRHG 774
Score = 60.5 bits (140), Expect = 6e-09
Identities = 52/190 (27%), Positives = 82/190 (43%), Gaps = 18/190 (9%)
Frame = +1
Query: 118 PLHIASRLGNVDIAVL-LLQHGADV--RAITADHYNPL--HIAAKQHNHDVAAALIEHNA 282
PLH A ++ D+ L L++ + + + ADH L +A + +A L+ H A
Sbjct: 284 PLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKA 343
Query: 283 PLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM-TPLHIAAQYDQQA--- 450
+ K G++ LH + G+L A L+ +GA + A TPLH+ A Y +
Sbjct: 344 DVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSA 403
Query: 451 --------VATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKA 603
+A LL+ GA+ G TPLH++ + LL+ L +
Sbjct: 404 DVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHE 463
Query: 604 GFTPLHLAAQ 633
G T L LA Q
Sbjct: 464 GSTALWLAVQ 473
Score = 53.2 bits (122), Expect = 9e-07
Identities = 52/192 (27%), Positives = 82/192 (42%), Gaps = 18/192 (9%)
Frame = +1
Query: 13 ETPVHLAARANHTDIIRI-LLRNGAAVEAKARERQ----TPLHIASRLGNVDIAVLLLQH 177
E P+H A + D++ + L+ + + K E L +A IA L+ H
Sbjct: 282 EYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSH 341
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGF-TALHLAAKYGNLK- 351
ADV + ++ LH ++ + A LI++ A + A T T LHL A Y + K
Sbjct: 342 KADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKH 401
Query: 352 ----------VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLE-KGADAKAVA 498
+A LL GA P+ G TPLH++ + V + LL+ K D +
Sbjct: 402 SADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKD 461
Query: 499 KNGHTPLHIAAR 534
G T L +A +
Sbjct: 462 HEGSTALWLAVQ 473
Score = 50.0 bits (114), Expect = 9e-06
Identities = 41/134 (30%), Positives = 58/134 (43%), Gaps = 7/134 (5%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNV-DIAVLLLQH 177
T +T +HLAA+ + I +LL NG A LH+A G + +I VLL +
Sbjct: 999 TKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTEC 1058
Query: 178 GADVRAITADHYNPLHIAAKQHNHDVAAALIE------HNAPLTATTKKGFTALHLAAKY 339
D A +PLHI Q+ + AAA+ + PL G T L LA
Sbjct: 1059 TVDAEAFNLRGQSPLHILG-QYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMK 1117
Query: 340 GNLKVANLLLAHGA 381
GN + ++ GA
Sbjct: 1118 GNANLCRAIVRSGA 1131
Score = 30.3 bits (65), Expect = 7.5
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Frame = +1
Query: 415 PLHIAAQYDQQAVATTLLEKGADAKAVAK------NGHTPLHIAARKNQMETAATLLEYG 576
PLH A + +++ V L + D++ K NG L +A + A TL+ +
Sbjct: 284 PLHKAIKVEREDVVFLYLIE-MDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHK 342
Query: 577 ALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
A + K+G++ LH Q+G L++ G
Sbjct: 343 ADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNG 375
>DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein.
Length = 591
Score = 94.7 bits (225), Expect = 3e-19
Identities = 56/176 (31%), Positives = 88/176 (50%), Gaps = 1/176 (0%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAV-EAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
+H A RA + ++ GA++ E + TPLH A+ G+++ LL HGAD+ +
Sbjct: 349 IHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHV 408
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
T + HIAA + ALI + A LTA +G T LHLAA +G+ ++L G
Sbjct: 409 TTRDWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSG 468
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
P K P+H AA + + L++ G + V NG+ P+H+AA + +
Sbjct: 469 VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHL 524
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/175 (29%), Positives = 79/175 (45%), Gaps = 1/175 (0%)
Frame = +1
Query: 121 LHIASRLGNVDIAVLLLQHGADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
+H A R G+V ++ GA + + H + PLH AA + + L+ H A +T
Sbjct: 349 IHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHV 408
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T + +TA H+AA G L+ +GA G TPLH+AA + +L G
Sbjct: 409 TTRDWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSG 468
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
D K P+H AA ++ L+++G G P+HLAA +GH
Sbjct: 469 VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGH 523
Score = 68.1 bits (159), Expect = 3e-11
Identities = 47/157 (29%), Positives = 67/157 (42%), Gaps = 1/157 (0%)
Frame = +1
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTAT-TKKGFTALHLAAKYGNLKVANLLLAHGAA 384
H+ +H A + + + ++ A + FT LH AA G+L+ + LL HGA
Sbjct: 345 HFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGAD 404
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
T HIAA Q A L+ GA+ A G TPLH+AA T +
Sbjct: 405 ITHVTTRDWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIM 464
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L G + K + P+H AA G LL++ G
Sbjct: 465 LRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 501
Score = 66.5 bits (155), Expect = 9e-11
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 4/177 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + + + LL +GA + T HIA+ G L+ +GA++ A
Sbjct: 381 TPLHWAAHSGSLECLHWLLWHGADITHVTTRDWTASHIAAIRGQDACVQALIMNGANLTA 440
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
PLH+AA + ++ + T K+ + +H AA +G L LL+
Sbjct: 441 QDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKW 500
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK----NGHTPLHIAAR 534
G + + NG P+H+AA L+ + + A V K NG L +A R
Sbjct: 501 GCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQR 557
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 4/175 (2%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T R T H+AA ++ L+ NGA + A+ TPLH+A+ G+ ++L+ G
Sbjct: 409 TTRDWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSG 468
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D + P+H AA L++ + G +HLAA G+L
Sbjct: 469 VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHLHCFK 528
Query: 361 LLLAHGAAPDQAGK----NGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT 513
L++ ++ Q K NG L +A ++ +Q + + +G+ A G T
Sbjct: 529 FLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFI--QGSPRPATDLQGET 581
>BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein.
Length = 716
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA A H DI +L++ GA ++ + +++TPL A+ +++ L++ GA V
Sbjct: 193 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 252
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A+ LH+AAK+ +++V L+ + + G+T + A +Y ++ + LLL+
Sbjct: 253 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 312
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G+ + LH AA +A LL D AV +G +PLHIAAR+N+ +
Sbjct: 313 KGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDC 372
Query: 553 AATLLEYGALTNAESKAGFTPLHLAA 630
L + ++K G TPL A+
Sbjct: 373 VVLFLSRDSDVTLKNKEGETPLQCAS 398
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKA--RERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
++ +AR + ++L +G K + +++PLH A+ G+VDI +L+Q GA++
Sbjct: 160 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 219
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D PL AA+ ++ + LI+ A + +G T LHLAAK G+ +V LL++
Sbjct: 220 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 279
Query: 376 GAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G + G TP+ A +Y + LL KG+D + LH AA ++
Sbjct: 280 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDI 339
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LL +A + G +PLH+AA++ + L L
Sbjct: 340 AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFL 377
Score = 84.2 bits (199), Expect = 4e-16
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA-DVR 192
TP+ AA NH + ++ L++ GA V+ K E T LH+A++ G+ ++ LL +G DV
Sbjct: 226 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 285
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ P+ A + + D+ L+ + + + LH AA G + +A +LLA
Sbjct: 286 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 345
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G +PLHIAA+ ++ L + +D K G TPL A+ +Q+ +
Sbjct: 346 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 405
Query: 553 A 555
A
Sbjct: 406 A 406
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPD--QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
L+ +A+ G L+ L+L G P+ +N +PLH AA+ + L++ GA+
Sbjct: 160 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 219
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+++ TPL AA N +E L++ GAL + + G T LHLAA++GH E+ LL
Sbjct: 220 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 279
Query: 673 G 675
G
Sbjct: 280 G 280
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A H D++++LL G+ + + E LH A+ G VDIA +LL D+
Sbjct: 291 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 350
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +PLHIAA+++ +D + ++ +T K+G T L A+ N +V + L
Sbjct: 351 HAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASL--NSQVWSALQ 408
Query: 370 AHGAAPDQA 396
A D A
Sbjct: 409 MSKALQDSA 417
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
LH AA+ G++ + ++L+ GA D ++ TPL AA+ + L++ GA
Sbjct: 195 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 254
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH+AA+K E LL G + N + G+TP+ A + H ++ LLL G
Sbjct: 255 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 314
Score = 39.9 bits (89), Expect = 0.009
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIAS 135
+ G++P+H+AAR N D + + L + V K +E +TPL AS
Sbjct: 355 IHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 398
>AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone
methyltransferase 1 protein.
Length = 1267
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA A H DI +L++ GA ++ + +++TPL A+ +++ L++ GA V
Sbjct: 744 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 803
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A+ LH+AAK+ +++V L+ + + G+T + A +Y ++ + LLL+
Sbjct: 804 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 863
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G+ + LH AA +A LL D AV +G +PLHIAAR+N+ +
Sbjct: 864 KGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDC 923
Query: 553 AATLLEYGALTNAESKAGFTPLHLAA 630
L + ++K G TPL A+
Sbjct: 924 VVLFLSRDSDVTLKNKEGETPLQCAS 949
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKA--RERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
++ +AR + ++L +G K + +++PLH A+ G+VDI +L+Q GA++
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D PL AA+ ++ + LI+ A + +G T LHLAAK G+ +V LL++
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 376 GAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G + G TP+ A +Y + LL KG+D + LH AA ++
Sbjct: 831 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDI 890
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LL +A + G +PLH+AA++ + L L
Sbjct: 891 AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFL 928
Score = 84.2 bits (199), Expect = 4e-16
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA-DVR 192
TP+ AA NH + ++ L++ GA V+ K E T LH+A++ G+ ++ LL +G DV
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 836
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ P+ A + + D+ L+ + + + LH AA G + +A +LLA
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G +PLHIAA+ ++ L + +D K G TPL A+ +Q+ +
Sbjct: 897 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 956
Query: 553 A 555
A
Sbjct: 957 A 957
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPD--QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
L+ +A+ G L+ L+L G P+ +N +PLH AA+ + L++ GA+
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+++ TPL AA N +E L++ GAL + + G T LHLAA++GH E+ LL
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 673 G 675
G
Sbjct: 831 G 831
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A H D++++LL G+ + + E LH A+ G VDIA +LL D+
Sbjct: 842 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 901
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +PLHIAA+++ +D + ++ +T K+G T L A+ N +V + L
Sbjct: 902 HAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASL--NSQVWSALQ 959
Query: 370 AHGAAPDQA 396
A D A
Sbjct: 960 MSKALQDSA 968
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
LH AA+ G++ + ++L+ GA D ++ TPL AA+ + L++ GA
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 805
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH+AA+K E LL G + N + G+TP+ A + H ++ LLL G
Sbjct: 806 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 865
Score = 39.9 bits (89), Expect = 0.009
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIAS 135
+ G++P+H+AAR N D + + L + V K +E +TPL AS
Sbjct: 906 IHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 949
>AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA A H DI +L++ GA ++ + +++TPL A+ +++ L++ GA V
Sbjct: 744 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 803
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A+ LH+AAK+ +++V L+ + + G+T + A +Y ++ + LLL+
Sbjct: 804 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 863
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G+ + LH AA +A LL D AV +G +PLHIAAR+N+ +
Sbjct: 864 KGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDC 923
Query: 553 AATLLEYGALTNAESKAGFTPLHLAA 630
L + ++K G TPL A+
Sbjct: 924 VVLFLSRDSDVTLKNKEGETPLQCAS 949
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKA--RERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
++ +AR + ++L +G K + +++PLH A+ G+VDI +L+Q GA++
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D PL AA+ ++ + LI+ A + +G T LHLAAK G+ +V LL++
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 376 GAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G + G TP+ A +Y + LL KG+D + LH AA ++
Sbjct: 831 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDI 890
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LL +A + G +PLH+AA++ + L L
Sbjct: 891 AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFL 928
Score = 84.2 bits (199), Expect = 4e-16
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA-DVR 192
TP+ AA NH + ++ L++ GA V+ K E T LH+A++ G+ ++ LL +G DV
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 836
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ P+ A + + D+ L+ + + + LH AA G + +A +LLA
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G +PLHIAA+ ++ L + +D K G TPL A+ +Q+ +
Sbjct: 897 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 956
Query: 553 A 555
A
Sbjct: 957 A 957
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPD--QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
L+ +A+ G L+ L+L G P+ +N +PLH AA+ + L++ GA+
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+++ TPL AA N +E L++ GAL + + G T LHLAA++GH E+ LL
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 673 G 675
G
Sbjct: 831 G 831
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A H D++++LL G+ + + E LH A+ G VDIA +LL D+
Sbjct: 842 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 901
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +PLHIAA+++ +D + ++ +T K+G T L A+ N +V + L
Sbjct: 902 HAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASL--NSQVWSALQ 959
Query: 370 AHGAAPDQA 396
A D A
Sbjct: 960 MSKALQDSA 968
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
LH AA+ G++ + ++L+ GA D ++ TPL AA+ + L++ GA
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 805
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH+AA+K E LL G + N + G+TP+ A + H ++ LLL G
Sbjct: 806 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 865
Score = 39.9 bits (89), Expect = 0.009
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIAS 135
+ G++P+H+AAR N D + + L + V K +E +TPL AS
Sbjct: 906 IHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 949
>AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA A H DI +L++ GA ++ + +++TPL A+ +++ L++ GA V
Sbjct: 744 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 803
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A+ LH+AAK+ +++V L+ + + G+T + A +Y ++ + LLL+
Sbjct: 804 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 863
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G+ + LH AA +A LL D AV +G +PLHIAAR+N+ +
Sbjct: 864 KGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDC 923
Query: 553 AATLLEYGALTNAESKAGFTPLHLAA 630
L + ++K G TPL A+
Sbjct: 924 VVLFLSRDSDVTLKNKEGETPLQCAS 949
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKA--RERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
++ +AR + ++L +G K + +++PLH A+ G+VDI +L+Q GA++
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D PL AA+ ++ + LI+ A + +G T LHLAAK G+ +V LL++
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 376 GAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G + G TP+ A +Y + LL KG+D + LH AA ++
Sbjct: 831 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDI 890
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LL +A + G +PLH+AA++ + L L
Sbjct: 891 AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFL 928
Score = 84.2 bits (199), Expect = 4e-16
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA-DVR 192
TP+ AA NH + ++ L++ GA V+ K E T LH+A++ G+ ++ LL +G DV
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 836
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ P+ A + + D+ L+ + + + LH AA G + +A +LLA
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G +PLHIAA+ ++ L + +D K G TPL A+ +Q+ +
Sbjct: 897 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 956
Query: 553 A 555
A
Sbjct: 957 A 957
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPD--QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
L+ +A+ G L+ L+L G P+ +N +PLH AA+ + L++ GA+
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+++ TPL AA N +E L++ GAL + + G T LHLAA++GH E+ LL
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 673 G 675
G
Sbjct: 831 G 831
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A H D++++LL G+ + + E LH A+ G VDIA +LL D+
Sbjct: 842 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 901
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +PLHIAA+++ +D + ++ +T K+G T L A+ N +V + L
Sbjct: 902 HAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASL--NSQVWSALQ 959
Query: 370 AHGAAPDQA 396
A D A
Sbjct: 960 MSKALQDSA 968
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
LH AA+ G++ + ++L+ GA D ++ TPL AA+ + L++ GA
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 805
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH+AA+K E LL G + N + G+TP+ A + H ++ LLL G
Sbjct: 806 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 865
Score = 39.9 bits (89), Expect = 0.009
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIAS 135
+ G++P+H+AAR N D + + L + V K +E +TPL AS
Sbjct: 906 IHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 949
>AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein.
Length = 803
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA A H DI +L++ GA ++ + +++TPL A+ +++ L++ GA V
Sbjct: 394 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 453
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A+ LH+AAK+ +++V L+ + + G+T + A +Y ++ + LLL+
Sbjct: 454 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 513
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G+ + LH AA +A LL D AV +G +PLHIAAR+N+ +
Sbjct: 514 KGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDC 573
Query: 553 AATLLEYGALTNAESKAGFTPLHLAA 630
L + ++K G TPL A+
Sbjct: 574 VVLFLSRDSDVTLKNKEGETPLQCAS 599
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKA--RERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
++ +AR + ++L +G K + +++PLH A+ G+VDI +L+Q GA++
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D PL AA+ ++ + LI+ A + +G T LHLAAK G+ +V LL++
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 480
Query: 376 GAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G + G TP+ A +Y + LL KG+D + LH AA ++
Sbjct: 481 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDI 540
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LL +A + G +PLH+AA++ + L L
Sbjct: 541 AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFL 578
Score = 84.2 bits (199), Expect = 4e-16
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA-DVR 192
TP+ AA NH + ++ L++ GA V+ K E T LH+A++ G+ ++ LL +G DV
Sbjct: 427 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 486
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ P+ A + + D+ L+ + + + LH AA G + +A +LLA
Sbjct: 487 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 546
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G +PLHIAA+ ++ L + +D K G TPL A+ +Q+ +
Sbjct: 547 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 606
Query: 553 A 555
A
Sbjct: 607 A 607
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPD--QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
L+ +A+ G L+ L+L G P+ +N +PLH AA+ + L++ GA+
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+++ TPL AA N +E L++ GAL + + G T LHLAA++GH E+ LL
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 480
Query: 673 G 675
G
Sbjct: 481 G 481
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A H D++++LL G+ + + E LH A+ G VDIA +LL D+
Sbjct: 492 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 551
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +PLHIAA+++ +D + ++ +T K+G T L A+ N +V + L
Sbjct: 552 HAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASL--NSQVWSALQ 609
Query: 370 AHGAAPDQA 396
A D A
Sbjct: 610 MSKALQDSA 618
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
LH AA+ G++ + ++L+ GA D ++ TPL AA+ + L++ GA
Sbjct: 396 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 455
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH+AA+K E LL G + N + G+TP+ A + H ++ LLL G
Sbjct: 456 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 515
Score = 39.9 bits (89), Expect = 0.009
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIAS 135
+ G++P+H+AAR N D + + L + V K +E +TPL AS
Sbjct: 556 IHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 599
>AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein.
Length = 917
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+H AA A H DI +L++ GA ++ + +++TPL A+ +++ L++ GA V
Sbjct: 394 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 453
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
A+ LH+AAK+ +++V L+ + + G+T + A +Y ++ + LLL+
Sbjct: 454 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 513
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G+ + LH AA +A LL D AV +G +PLHIAAR+N+ +
Sbjct: 514 KGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDC 573
Query: 553 AATLLEYGALTNAESKAGFTPLHLAA 630
L + ++K G TPL A+
Sbjct: 574 VVLFLSRDSDVTLKNKEGETPLQCAS 599
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAVEAKA--RERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
++ +AR + ++L +G K + +++PLH A+ G+VDI +L+Q GA++
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
+ D PL AA+ ++ + LI+ A + +G T LHLAAK G+ +V LL++
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 480
Query: 376 GAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
G + G TP+ A +Y + LL KG+D + LH AA ++
Sbjct: 481 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDI 540
Query: 553 AATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
A LL +A + G +PLH+AA++ + L L
Sbjct: 541 AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFL 578
Score = 84.2 bits (199), Expect = 4e-16
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA-DVR 192
TP+ AA NH + ++ L++ GA V+ K E T LH+A++ G+ ++ LL +G DV
Sbjct: 427 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 486
Query: 193 AITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLA 372
+ P+ A + + D+ L+ + + + LH AA G + +A +LLA
Sbjct: 487 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 546
Query: 373 HGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMET 552
+G +PLHIAA+ ++ L + +D K G TPL A+ +Q+ +
Sbjct: 547 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 606
Query: 553 A 555
A
Sbjct: 607 A 607
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPD--QAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKA 492
L+ +A+ G L+ L+L G P+ +N +PLH AA+ + L++ GA+
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 493 VAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEG 672
+++ TPL AA N +E L++ GAL + + G T LHLAA++GH E+ LL
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 480
Query: 673 G 675
G
Sbjct: 481 G 481
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A H D++++LL G+ + + E LH A+ G VDIA +LL D+
Sbjct: 492 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 551
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
A+ +PLHIAA+++ +D + ++ +T K+G T L A+ N +V + L
Sbjct: 552 HAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASL--NSQVWSALQ 609
Query: 370 AHGAAPDQA 396
A D A
Sbjct: 610 MSKALQDSA 618
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +1
Query: 319 LHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVA 498
LH AA+ G++ + ++L+ GA D ++ TPL AA+ + L++ GA
Sbjct: 396 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 455
Query: 499 KNGHTPLHIAARKNQMETAATLLEYGAL-TNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH+AA+K E LL G + N + G+TP+ A + H ++ LLL G
Sbjct: 456 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 515
Score = 39.9 bits (89), Expect = 0.009
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIAS 135
+ G++P+H+AAR N D + + L + V K +E +TPL AS
Sbjct: 556 IHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 599
>DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein.
Length = 593
Score = 94.3 bits (224), Expect = 4e-19
Identities = 56/176 (31%), Positives = 88/176 (50%), Gaps = 1/176 (0%)
Frame = +1
Query: 22 VHLAARANHTDIIRILLRNGAAV-EAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
+H A RA + ++ GA++ E + TPLH A+ G+++ LL HGAD+ +
Sbjct: 121 IHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHV 180
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
T + HIAA + ALI + A LTA +G T LHLAA +G+ ++L G
Sbjct: 181 TTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSG 240
Query: 379 AAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
P K P+H AA + + L++ G + V NG+ P+H+AA + +
Sbjct: 241 VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHL 296
Score = 88.2 bits (209), Expect = 3e-17
Identities = 53/175 (30%), Positives = 80/175 (45%), Gaps = 1/175 (0%)
Frame = +1
Query: 121 LHIASRLGNVDIAVLLLQHGADVRAITADH-YNPLHIAAKQHNHDVAAALIEHNAPLTAT 297
+H A R G+V ++ GA + + H + PLH AA + + L+ H A +T
Sbjct: 121 IHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHV 180
Query: 298 TKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKG 477
T +G+TA H+AA G L+ +GA G TPLH+AA + +L G
Sbjct: 181 TTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSG 240
Query: 478 ADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
D K P+H AA ++ L+++G G P+HLAA +GH
Sbjct: 241 VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGH 295
Score = 82.6 bits (195), Expect = 1e-15
Identities = 63/232 (27%), Positives = 102/232 (43%), Gaps = 7/232 (3%)
Frame = +1
Query: 1 TVRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHG 180
T RG T H+AA ++ L+ NGA + A+ TPLH+A+ G+ ++L+ G
Sbjct: 181 TTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSG 240
Query: 181 ADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
D + P+H AA L++ + G +HLAA G+L
Sbjct: 241 VDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHLHCFK 300
Query: 361 LLLAHGAAPDQAGK----NGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHT--PLH 522
L++ ++ Q K NG L +A ++ +Q + + + K + P H
Sbjct: 301 FLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQETLAFPGH 360
Query: 523 IAARKNQMETAATLLEYGALT-NAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+AA K + L+E G + N + G TP+H AA QGH E L++ G
Sbjct: 361 VAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMG 412
Score = 81.0 bits (191), Expect = 4e-15
Identities = 62/228 (27%), Positives = 102/228 (44%), Gaps = 7/228 (3%)
Frame = +1
Query: 7 RGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
RG TP+HLAA H+ ++I+LR+G + P+H A+ G + LL++ G
Sbjct: 216 RGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCS 275
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTK----KGFTALHLAAKYGNLKV 354
+ + + P+H+AA + + L+ + T K G L LA ++ +
Sbjct: 276 IEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNI 335
Query: 355 ANLLL-AHGAAPDQAGKNGMT-PLHIAAQYDQQAVATTLLEKGA-DAKAVAKNGHTPLHI 525
+ A D + + P H+AA + L+E G + A NG TP+H
Sbjct: 336 LQFIQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHK 395
Query: 526 AARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
AA + +E L++ GA +N +KAG P +A + H LL E
Sbjct: 396 AAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLLEE 443
Score = 72.1 bits (169), Expect = 2e-12
Identities = 60/226 (26%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
TP+H AA + + + LL +GA + T HIA+ G L+ +GA++ A
Sbjct: 153 TPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTA 212
Query: 196 ITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAH 375
PLH+AA + ++ + T K+ + +H AA +G L LL+
Sbjct: 213 QDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKW 272
Query: 376 GAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK----NGHTPLHIAAR--K 537
G + + NG P+H+AA L+ + + A V K NG L +A R K
Sbjct: 273 GCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFK 332
Query: 538 NQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
+ EY + + P H+AA +G M L+E G
Sbjct: 333 QNILQFIQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDG 378
Score = 70.9 bits (166), Expect = 4e-12
Identities = 48/157 (30%), Positives = 68/157 (43%), Gaps = 1/157 (0%)
Frame = +1
Query: 208 HYNPLHIAAKQHNHDVAAALIEHNAPLTAT-TKKGFTALHLAAKYGNLKVANLLLAHGAA 384
H+ +H A + + + ++ A + FT LH AA G+L+ + LL HGA
Sbjct: 117 HFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGAD 176
Query: 385 PDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
G T HIAA Q A L+ GA+ A G TPLH+AA T +
Sbjct: 177 ITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIM 236
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L G + K + P+H AA G LL++ G
Sbjct: 237 LRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWG 273
>AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ34236 fis, clone FCBBF3027199, weakly similar to
ANKYRIN. ).
Length = 505
Score = 93.9 bits (223), Expect = 5e-19
Identities = 76/227 (33%), Positives = 106/227 (46%), Gaps = 9/227 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVE---AKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
TP+H AA + HTD + +L+ +G + QTPL +A G+VD LLL+ G+
Sbjct: 83 TPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVDCVHLLLEKGST 142
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
A LH A D AAL++H+A + KG T +HLA+ G+ V L
Sbjct: 143 ADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTL 202
Query: 367 L--AHGAAPDQAG--KNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR 534
L A P AG +G +P+H A+ + LLE + + N TPLH A
Sbjct: 203 LQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEH-SPFSYLEGNPFTPLHCAVI 261
Query: 535 KNQMETAATLL-EYGA-LTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
NQ T LL GA + N+ G TPLH AA + +LL+
Sbjct: 262 NNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADNVSGLRMLLQ 308
Score = 89.8 bits (213), Expect = 9e-18
Identities = 73/231 (31%), Positives = 100/231 (43%), Gaps = 7/231 (3%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V G+TP+ LA H D + +LL G+ +A +T LH + G D LL H A
Sbjct: 115 VYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDA 174
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIE---HNAPLTA-TTKKGFTALHLAAKYGNLK 351
V P+H+A+ + V L++ PL A G++ +H A+ G+
Sbjct: 175 FVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHED 234
Query: 352 VANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK---NGHTPLH 522
LLL H G N TPLH A +Q + T +L AK V G TPLH
Sbjct: 235 CLELLLEHSPFSYLEG-NPFTPLHCAVINNQDS-TTEMLLGALGAKIVNSRDTKGRTPLH 292
Query: 523 IAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
AA + + LL++ A NA G T L AA+ G T LL G
Sbjct: 293 AAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRG 343
Score = 87.4 bits (207), Expect = 5e-17
Identities = 65/229 (28%), Positives = 101/229 (44%), Gaps = 8/229 (3%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
+P+HLAA H + ++ L ++ + + +T L +A+ G+ + +L HGA
Sbjct: 16 SPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALI 75
Query: 196 ITADH-YNPLHIAAKQHNHDVAAALIE--HNAPLT-ATTKKGFTALHLAAKYGNLKVANL 363
+ PLH AA + D LI+ A +T G T L LA G++ +L
Sbjct: 76 KERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVDCVHL 135
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQ 543
LL G+ D A G T LH A + LL+ A G TP+H+A+
Sbjct: 136 LLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGH 195
Query: 544 METAATLLEYGALTN----AESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
TLL+ T+ +G++P+H A+ GH + LLLE P
Sbjct: 196 TAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSP 244
Score = 78.2 bits (184), Expect = 3e-14
Identities = 66/226 (29%), Positives = 91/226 (40%), Gaps = 7/226 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G +P+H A+ H D + +LL + + TPLH A + N D +L
Sbjct: 220 GYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPF-TPLHCAV-INNQDSTTEMLLGALGA 277
Query: 190 RAITADHYN---PLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVAN 360
+ + + PLH AA N L++H A + AT G TAL AA+ G
Sbjct: 278 KIVNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVE 337
Query: 361 LLLAHGAAP-DQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV-AKNG--HTPLHIA 528
LL G A +N T LH+A + A +L + D + A N PLHIA
Sbjct: 338 FLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIA 397
Query: 529 ARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
AR LL +GA A + G TP A C L+
Sbjct: 398 ARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALI 443
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/194 (28%), Positives = 83/194 (42%), Gaps = 4/194 (2%)
Frame = +1
Query: 115 TPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAP-LT 291
+PLH+A+ G+ + L + ++ L +A ++ + + L H A L
Sbjct: 16 SPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALI 75
Query: 292 ATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKN---GMTPLHIAAQYDQQAVATT 462
K+ +T LH AA G+ +LL+ G D G TPL +A
Sbjct: 76 KERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVDCVHL 135
Query: 463 LLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGH 642
LLEKG+ A A G T LH A + A LL++ A G TP+HLA+ GH
Sbjct: 136 LLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGH 195
Query: 643 TEMCALLLEGGPGT 684
T + LL+ T
Sbjct: 196 TAVLRTLLQAALST 209
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/90 (33%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Frame = +1
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGA-LT 585
++PLH+AA TL E + G T L +A + E L +GA
Sbjct: 15 VSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASAL 74
Query: 586 NAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
E K +TPLH AA GHT+ LL++ G
Sbjct: 75 IKERKRKWTPLHAAAASGHTDSLHLLIDSG 104
Score = 30.7 bits (66), Expect = 5.7
Identities = 14/35 (40%), Positives = 18/35 (51%)
Frame = +1
Query: 565 LEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ + L + ES +PLHLAA GH E L E
Sbjct: 1 MSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAE 35
>BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein.
Length = 725
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a
protein.
Length = 1065
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 87.4 bits (207), Expect = 5e-17
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ + G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA ++G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin
protein.
Length = 604
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein.
Length = 895
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein
alternative isoform protein.
Length = 895
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 377 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 436
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 437 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 90.2 bits (214), Expect = 7e-18
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 9/229 (3%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G TP+ A+ D LL+ GA V ++T LH+A++ GN LLL A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANL 363
+ PLH+ + + A L++ AP T K TALH +A Y N + L
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHI 525
L+ H + G PLH AA + D AV T + A +++ G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 526 AARKNQMETAATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
A + L Y + F TPLH AA GH ++ LLLE
Sbjct: 228 AVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 536
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 537 HEVIQFMLEHGALSIA 552
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 180 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 236
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 237 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 297 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 356
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 388 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 447
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 507
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 508 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 548
Score = 70.1 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Frame = +1
Query: 22 VHLAA-RANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAI 198
VH AA + + R+++ N A + + + +TPL +D A LL+ GADV
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 199 TADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHG 378
LH+AA++ N+ L+ A + T LHL ++ + K LLL
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 379 A--APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAAR---KNQ 543
A D KN T LH +A Y+ L++ ++ G PLH AA +
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 544 METAATLLEYG---ALTNAESKAGFTPLHLAAQQGHTEMCALL 663
+ T +L+ +L N + G TPLH A G+ + +L
Sbjct: 198 VHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL 240
Score = 51.6 bits (118), Expect = 3e-06
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 319 LHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAV 495
+H AA G+ + L++ + A D+ + G TPL D+ A LL+ GAD
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 496 AKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ T LH+AA+K LL A + TPLHL + + ALLL+
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135
>AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog
protein.
Length = 1013
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 3/221 (1%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILL-RNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVR 192
TP+H AA H I+ +LL RN + + TPLH A++ + + L+H +
Sbjct: 205 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 264
Query: 193 AITADHYNPLHIAAKQHNHDVAAALI--EHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
+ AA + + DV ++ + + + K G TALH AA G++ LL
Sbjct: 265 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 324
Query: 367 LAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQM 546
L + A D TPL A + + V TL++ GA V ++GH+ LH AA
Sbjct: 325 LENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNA 384
Query: 547 ETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
+ L+E N + AG TPL AA G+ A+L+E
Sbjct: 385 DVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLME 425
Score = 89.0 bits (211), Expect = 2e-17
Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 2/196 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +H AA + H +++LL N A V+A + TPL A +G+ D+ L++ GA V
Sbjct: 305 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 364
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLL 369
+ D ++ LH AA N DV LIE+ G T L AA G + +L+
Sbjct: 365 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 424
Query: 370 AHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNG--HTPLHIAARKNQ 543
+ A P+ K G T LH + LL+ A + N +TPL A +
Sbjct: 425 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGER 484
Query: 544 METAATLLEYGALTNA 591
E +LE+GAL+ A
Sbjct: 485 HEVIQFMLEHGALSIA 500
Score = 84.6 bits (200), Expect = 3e-16
Identities = 68/219 (31%), Positives = 95/219 (43%), Gaps = 9/219 (4%)
Frame = +1
Query: 40 ANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNP 219
A+ D LL+ GA V ++T LH+A++ GN LLL A+ + P
Sbjct: 6 ADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTP 65
Query: 220 LHIAAKQHNHDVAAALIEHNAPLTATT--KKGFTALHLAAKYGNLKVANLLLAHGAAPDQ 393
LH+ + + A L++ AP T K TALH +A Y N + LL+ H +
Sbjct: 66 LHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGI 125
Query: 394 AGKNGMTPLHIAAQY-DQQAVATT-LLEKGADAKAVAK----NGHTPLHIAARKNQMETA 555
G PLH AA + D AV T + A +++ G TPLH A +
Sbjct: 126 PDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVV 185
Query: 556 ATLLEYGALTNAESKAGF-TPLHLAAQQGHTEMCALLLE 669
L Y + F TPLH AA GH ++ LLLE
Sbjct: 186 DVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 224
Score = 83.8 bits (198), Expect = 6e-16
Identities = 72/237 (30%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Frame = +1
Query: 4 VRGETPVHLAARANHTD-----IIRILLRNGAAVEAKAR----ERQTPLHIASRLGNVDI 156
V G+ P+H AA NH D +R +L + A E+ E +TPLH A GNV +
Sbjct: 128 VEGKIPLHWAA--NHKDPSAVHTVRCIL-DAAPTESLLNWQDYEGRTPLHFAVADGNVTV 184
Query: 157 A-VLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATT-KKGFTALHLA 330
VL ++ + PLH AA + + L+E N T + +G T LH A
Sbjct: 185 VDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 244
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLL--EKGADAKAVAKN 504
A+ + + L H + D + G T AA V T+L + D K
Sbjct: 245 AQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKY 304
Query: 505 GHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
G T LH AA + T LLE A +A TPL A + GH ++ L++GG
Sbjct: 305 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 361
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V TP+ A H D+I+ L++ GA V+ ++ + LH A+ GN D+ +L+++
Sbjct: 336 VMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKI 395
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
+ PL AA + A L+E+NA K+G TALH + G L L
Sbjct: 396 NPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKL 455
Query: 364 LLAHGAAPDQAGKN--GMTPLHIAAQYDQQAVATTLLEKGA 480
LL A P+Q N TPL A ++ V +LE GA
Sbjct: 456 LLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGA 496
Score = 68.9 bits (161), Expect = 2e-11
Identities = 66/228 (28%), Positives = 96/228 (42%), Gaps = 10/228 (4%)
Frame = +1
Query: 16 TPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRA 195
T +HLAA+ + +++LL A K E TPLH+ +R + LLL+ A
Sbjct: 31 TALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEV 90
Query: 196 ITAD--HYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGN-LKVANLL 366
T D LH +A +N + LI+H++ + +G LH AA + + V +
Sbjct: 91 DTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVR 150
Query: 367 LAHGAAPDQAGKN-----GMTPLHIAAQYDQQAVATTLLE-KGADAKAVAKNGHTPLHIA 528
AAP ++ N G TPLH A V L + + + TPLH A
Sbjct: 151 CILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWA 210
Query: 529 ARKNQMETAATLLEYG-ALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
A + LLE + T G TPLH AAQ E + L+
Sbjct: 211 ALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLK 258
>AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens
cDNA FLJ42568 fis, clone BRACE3007625, moderately
similar to Rattus norvegicus espin (Espn). ).
Length = 1005
Score = 93.1 bits (221), Expect = 9e-19
Identities = 68/223 (30%), Positives = 103/223 (46%), Gaps = 3/223 (1%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVD-IAVLLLQHGAD 186
G +P+HLAAR H ++ LL G + + RE PLH A+ G++ + +L HG+
Sbjct: 104 GVSPLHLAARFGHPVLVEWLLHEGHSATLETREGARPLHHAAVSGDLTCLKLLTAAHGSS 163
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAALIEH-NAPLTATTKKGFTALHLAAKYGNLKVANL 363
V T +PL++A ++ + +A L++ A + G +ALH AA G+ +
Sbjct: 164 VNRRTRSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVW 223
Query: 364 LLAHGAAPDQAGKN-GMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKN 540
L+ A N G T LH AA+ + LL G + G TPLH AA
Sbjct: 224 LVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGTPILRDSWGG-TPLHDAAENG 282
Query: 541 QMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLE 669
QME TL+ + + + G+T LA GH + L E
Sbjct: 283 QMECCQTLVSHHVDPSLRDEDGYTAADLAEYHGHRDCAQYLRE 325
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/225 (29%), Positives = 98/225 (43%), Gaps = 6/225 (2%)
Frame = +1
Query: 10 GETPVH-LAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGAD 186
G TP H AA + ++ ++ G ++ + +PLH+A+R G+ + LL G
Sbjct: 70 GATPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLVEWLLHEGHS 129
Query: 187 VRAITADHYNPLHIAAKQHNHDVAAAL-IEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
T + PLH AA + L H + + T+ G + L+LA + G+L +A
Sbjct: 130 ATLETREGARPLHHAAVSGDLTCLKLLTAAHGSSVNRRTRSGASPLYLACQEGHLHLAQF 189
Query: 364 LLAH-GAAPDQAGKNGMTPLHIAA---QYDQQAVATTLLEKGADAKAVAKNGHTPLHIAA 531
L+ GA +GM+ LH AA Y T + G A+ G T LH AA
Sbjct: 190 LVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTFTDIGLTAR--DNEGATALHFAA 247
Query: 532 RKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLL 666
R LL G +S G TPLH AA+ G E C L+
Sbjct: 248 RGGHTPILDRLLLMGTPILRDSWGG-TPLHDAAENGQMECCQTLV 291
Score = 70.9 bits (166), Expect = 4e-12
Identities = 55/192 (28%), Positives = 91/192 (47%), Gaps = 4/192 (2%)
Frame = +1
Query: 106 ERQTPLHIASRLGNVDIAVLLLQHGADVRAIT-ADHYNPLHIAAKQHNHDVAAALIEH-N 279
E+Q L +A++ G+V LL+ GA IT A +H A + + D L++
Sbjct: 2 EKQRAL-VAAKDGDVATLERLLEAGALGPGITDALGAGLVHHATRAGHLDCVKFLVQRAQ 60
Query: 280 APLTATTKKGFTALHLAAKYGNL-KVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVA 456
P G T H AA G+L ++ L+ G +G++PLH+AA++ +
Sbjct: 61 LPGNQRAHNGATPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLV 120
Query: 457 TTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL-LEYGALTNAESKAGFTPLHLAAQ 633
LL +G A + G PLH AA + L +G+ N +++G +PL+LA Q
Sbjct: 121 EWLLHEGHSATLETREGARPLHHAAVSGDLTCLKLLTAAHGSSVNRRTRSGASPLYLACQ 180
Query: 634 QGHTEMCALLLE 669
+GH + L++
Sbjct: 181 EGHLHLAQFLVK 192
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Frame = +1
Query: 325 LAAKYGNLKVANLLLAHGA-APDQAGKNGMTPLHIAAQYDQQAVATTLLEKGA-DAKAVA 498
+AAK G++ LL GA P G +H A + L+++ A
Sbjct: 8 VAAKDGDVATLERLLEAGALGPGITDALGAGLVHHATRAGHLDCVKFLVQRAQLPGNQRA 67
Query: 499 KNGHTPLHIAARKNQMETAATLL-EYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
NG TP H AA + L+ E G + +G +PLHLAA+ GH + LL G
Sbjct: 68 HNGATPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLVEWLLHEG 127
Score = 37.9 bits (84), Expect = 0.038
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Frame = +1
Query: 424 IAAQYDQQAVATTLLEKGADAKAVAKN-GHTPLHIAARKNQMETAATLLEYGALT-NAES 597
+AA+ A LLE GA + G +H A R ++ L++ L N +
Sbjct: 8 VAAKDGDVATLERLLEAGALGPGITDALGAGLVHHATRAGHLDCVKFLVQRAQLPGNQRA 67
Query: 598 KAGFTPLHLAAQQGH-TEMCALLLEGGPGTQ 687
G TP H AA G E+C L+ EGG G Q
Sbjct: 68 HNGATPAHDAAATGSLAELCWLVREGGCGLQ 98
>AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 92.7 bits (220), Expect = 1e-18
Identities = 58/172 (33%), Positives = 83/172 (48%)
Frame = +1
Query: 49 TDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHI 228
T+II L+ G A++ + ++ T LH AS G A LL++ GA+V A LH+
Sbjct: 1 TEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHL 60
Query: 229 AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNG 408
A + + L+ + G T LH+AA+Y +L + LLL + + + G
Sbjct: 61 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
T LH+AA + + VA LLE GAD V G TPL A N E A L
Sbjct: 121 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 172
Score = 83.8 bits (198), Expect = 6e-16
Identities = 59/176 (33%), Positives = 81/176 (46%)
Frame = +1
Query: 151 DIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA 330
+I L+ G + D LH A+ A LI+ A + A K G TALHLA
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
+ + + +LL G+ D G T LH+AA+Y+ ++ LL + G
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGD 121
Query: 511 TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
T LH+AA N + A LLE GA T + AG TPL A + E+ ALLL P
Sbjct: 122 TALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEV-ALLLTKAP 176
Score = 81.8 bits (193), Expect = 2e-15
Identities = 52/145 (35%), Positives = 70/145 (48%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ AALI L K G TALH A+ +G + A LL+ GA K G T LH+A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
Q LL G+ A G T LH+AAR N + LL + +++AG
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGD 121
Query: 610 TPLHLAAQQGHTEMCALLLEGGPGT 684
T LH+AA H ++ +LLE G T
Sbjct: 122 TALHVAAALNHKKVAKILLEAGADT 146
Score = 63.3 bits (147), Expect = 9e-10
Identities = 40/119 (33%), Positives = 57/119 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +HLA + +H+ R+LL G+ + K T LH+A+R ++ I LLL V
Sbjct: 54 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 113
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
LH+AA ++ VA L+E A T G T L A + N +VA LL
Sbjct: 114 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 172
>AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 92.7 bits (220), Expect = 1e-18
Identities = 58/172 (33%), Positives = 83/172 (48%)
Frame = +1
Query: 49 TDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHI 228
T+II L+ G A++ + ++ T LH AS G A LL++ GA+V A LH+
Sbjct: 1 TEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHL 60
Query: 229 AAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNG 408
A + + L+ + G T LH+AA+Y +L + LLL + + + G
Sbjct: 61 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 409 MTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATL 564
T LH+AA + + VA LLE GAD V G TPL A N E A L
Sbjct: 121 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 172
Score = 83.8 bits (198), Expect = 6e-16
Identities = 59/176 (33%), Positives = 81/176 (46%)
Frame = +1
Query: 151 DIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLA 330
+I L+ G + D LH A+ A LI+ A + A K G TALHLA
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 331 AKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKNGH 510
+ + + +LL G+ D G T LH+AA+Y+ ++ LL + G
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGD 121
Query: 511 TPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGGP 678
T LH+AA N + A LLE GA T + AG TPL A + E+ ALLL P
Sbjct: 122 TALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEV-ALLLTKAP 176
Score = 81.8 bits (193), Expect = 2e-15
Identities = 52/145 (35%), Positives = 70/145 (48%)
Frame = +1
Query: 250 DVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIA 429
++ AALI L K G TALH A+ +G + A LL+ GA K G T LH+A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 430 AQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKAGF 609
Q LL G+ A G T LH+AAR N + LL + +++AG
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGD 121
Query: 610 TPLHLAAQQGHTEMCALLLEGGPGT 684
T LH+AA H ++ +LLE G T
Sbjct: 122 TALHVAAALNHKKVAKILLEAGADT 146
Score = 63.3 bits (147), Expect = 9e-10
Identities = 40/119 (33%), Positives = 57/119 (47%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G T +HLA + +H+ R+LL G+ + K T LH+A+R ++ I LLL V
Sbjct: 54 GNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 113
Query: 190 RAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLL 366
LH+AA ++ VA L+E A T G T L A + N +VA LL
Sbjct: 114 HEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 172
>AF403033-1|AAL57352.1| 434|Homo sapiens ankyrin repeat
domain-containing SOCS box protein Asb-15 protein.
Length = 434
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/133 (37%), Positives = 72/133 (54%)
Frame = +1
Query: 244 NHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLH 423
++D+ + LI+HN L K ++A+H AAK G + LLL HG G+TPL
Sbjct: 2 SYDMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLG 61
Query: 424 IAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYGALTNAESKA 603
+AA+Y V L+ KG D A+A +G + L AA + + LLEYG N ++A
Sbjct: 62 VAAEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNRA 121
Query: 604 GFTPLHLAAQQGH 642
G P+H AA +GH
Sbjct: 122 GHLPIHRAAYEGH 134
Score = 82.6 bits (195), Expect = 1e-15
Identities = 52/175 (29%), Positives = 85/175 (48%)
Frame = +1
Query: 52 DIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADVRAITADHYNPLHIA 231
D++ L+++ +++ +R + +H A++ G DI LLL+HG +V PL +A
Sbjct: 4 DMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVA 63
Query: 232 AKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANLLLAHGAAPDQAGKNGM 411
A+ + DV LI + A G + L AA GN +LLL +G + + + G
Sbjct: 64 AEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNRAGH 123
Query: 412 TPLHIAAQYDQQAVATTLLEKGADAKAVAKNGHTPLHIAARKNQMETAATLLEYG 576
P+H AA Y+ +A L A+ K+G TP+H AA + L+E G
Sbjct: 124 LPIHRAA-YEGHYLALKYLIPVTSKNAIRKSGLTPIHSAADGQNAQCLELLIENG 177
Score = 78.2 bits (184), Expect = 3e-14
Identities = 51/178 (28%), Positives = 80/178 (44%)
Frame = +1
Query: 142 GNVDIAVLLLQHGADVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTAL 321
G+ D+ L++H + ++ +H AAKQ D+ A L++H + G T L
Sbjct: 1 GSYDMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPL 60
Query: 322 HLAAKYGNLKVANLLLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAK 501
+AA+YG+ V L+ G +G + L AA + LLE G +
Sbjct: 61 GVAAEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNR 120
Query: 502 NGHTPLHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
GH P+H AA + L+ + NA K+G TP+H AA + + LL+E G
Sbjct: 121 AGHLPIHRAAYEGHYLALKYLIPVTS-KNAIRKSGLTPIHSAADGQNAQCLELLIENG 177
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/233 (26%), Positives = 99/233 (42%), Gaps = 9/233 (3%)
Frame = +1
Query: 4 VRGETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGA 183
V+ + +H AA+ DI+ +LL++G V + TPL +A+ G+ D+ L+ G
Sbjct: 21 VKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGG 80
Query: 184 DVRAITADHYNPLHIAAKQHNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNLKVANL 363
DV A+ D + L AA N D + L+E+ + G +H AA G+
Sbjct: 81 DVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNRAGHLPIHRAAYEGHYLALKY 140
Query: 364 LLAHGAAPDQAGKNGMTPLHIAAQYDQQAVATTLLEKGADAKAVAKN---------GHTP 516
L+ + + K+G+TP+H AA L+E G D + + T
Sbjct: 141 LIP-VTSKNAIRKSGLTPIHSAADGQNAQCLELLIENGFDVNTLLADHISQSYDDERKTA 199
Query: 517 LHIAARKNQMETAATLLEYGALTNAESKAGFTPLHLAAQQGHTEMCALLLEGG 675
L+ N + LL GA N + L +A + + E+ LLL G
Sbjct: 200 LYFGVSNNDVHCTEVLLAAGADPNLDP---LNCLLVAVRANNYEIVRLLLSHG 249
Score = 41.1 bits (92), Expect = 0.004
Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Frame = +1
Query: 10 GETPVHLAARANHTDIIRILLRNGAAVEAKARERQTPLHIASRLGNVDIAVLLLQHGADV 189
G P+H AA H ++ L+ + A + TP+H A+ N LL+++G DV
Sbjct: 122 GHLPIHRAAYEGHYLALKYLIPV-TSKNAIRKSGLTPIHSAADGQNAQCLELLIENGFDV 180
Query: 190 RAITADHYNPLHIAAKQ-------HNHDVAAALIEHNAPLTATTKKGFTALHLAAKYGNL 348
+ ADH + + ++ N+DV + A L +A + N
Sbjct: 181 NTLLADHISQSYDDERKTALYFGVSNNDVHCTEVLLAAGADPNLDP-LNCLLVAVRANNY 239
Query: 349 KVANLLLAHGA 381
++ LLL+HGA
Sbjct: 240 EIVRLLLSHGA 250
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,718,455
Number of Sequences: 237096
Number of extensions: 2879879
Number of successful extensions: 19993
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7575
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13560
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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