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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= cesb0046
         (423 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X87248-1|CAA60698.1|  341|Homo sapiens HP8 peptide protein.            31   2.1  
AF272349-1|AAL36980.1|  193|Homo sapiens quaking protein 3 protein.    31   2.1  
BC011571-1|AAH11571.1|  903|Homo sapiens ITCH protein protein.         30   2.8  
AL356299-4|CAI17959.1|  903|Homo sapiens itchy homolog E3 ubiqui...    30   2.8  
AL356299-3|CAI17960.1|  862|Homo sapiens itchy homolog E3 ubiqui...    30   2.8  
AL109923-6|CAI21458.1|  903|Homo sapiens itchy homolog E3 ubiqui...    30   2.8  
AL109923-5|CAI21459.1|  862|Homo sapiens itchy homolog E3 ubiqui...    30   2.8  
AF095745-1|AAK39399.1|  862|Homo sapiens ubiquitin protein ligas...    30   2.8  
AF038564-1|AAC04845.1|  739|Homo sapiens atrophin-1 interacting ...    30   2.8  
AB056663-1|BAB39389.1|  862|Homo sapiens ubiquitin protein ligas...    30   2.8  
U77457-1|AAC13544.1|  161|Homo sapiens LIM-homeodomain protein L...    29   4.9  
BC113491-1|AAI13492.1|  372|Homo sapiens LIM homeobox transcript...    29   4.9  
BC112120-1|AAI12121.1|  372|Homo sapiens LIM homeobox transcript...    29   4.9  
BC069601-1|AAH69601.1|  372|Homo sapiens LIM homeobox transcript...    29   4.9  
BC069588-1|AAH69588.1|  377|Homo sapiens LMX1B protein protein.        29   4.9  
AL161908-2|CAH70295.1|  372|Homo sapiens LIM homeobox transcript...    29   4.9  
AL161908-1|CAH70294.1|  402|Homo sapiens LIM homeobox transcript...    29   4.9  
AL161731-2|CAI40918.1|  372|Homo sapiens LIM homeobox transcript...    29   4.9  
AL161731-1|CAI40917.1|  402|Homo sapiens LIM homeobox transcript...    29   4.9  
AF059575-1|AAC27294.1|  379|Homo sapiens LIM homeodomain protein...    29   4.9  
AF057135-1|AAC39738.1|  372|Homo sapiens LIM homeodomain protein...    29   4.9  
AK055759-1|BAB71005.1|  171|Homo sapiens protein ( Homo sapiens ...    29   6.5  
AB037158-1|BAA96867.1|  190|Homo sapiens DSCR6a protein.               29   6.5  
U94190-1|AAC15791.1| 1663|Homo sapiens Duo protein.                    29   8.5  
AL354991-1|CAO03638.1|  645|Homo sapiens WNK lysine deficient pr...    29   8.5  
AK131379-1|BAD18530.1|  851|Homo sapiens protein ( Homo sapiens ...    29   8.5  

>X87248-1|CAA60698.1|  341|Homo sapiens HP8 peptide protein.
          Length = 341

 Score = 30.7 bits (66), Expect = 2.1
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = +2

Query: 320 CACTAWSPRRQPAPHEILTPKPR 388
           C C+  +PRR+P P    TP+PR
Sbjct: 204 CTCSPVTPRRRPRPCPARTPRPR 226


>AF272349-1|AAL36980.1|  193|Homo sapiens quaking protein 3 protein.
          Length = 193

 Score = 30.7 bits (66), Expect = 2.1
 Identities = 21/51 (41%), Positives = 26/51 (50%)
 Frame = +2

Query: 257 SEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSSGCR 409
           +E ACGGRA A      R      +A  P R+PA     TP P RP++G R
Sbjct: 79  AESACGGRASA------RCRPPRGSAREPEREPARSG--TPGPERPAAGAR 121


>BC011571-1|AAH11571.1|  903|Homo sapiens ITCH protein protein.
          Length = 903

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 225 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 269


>AL356299-4|CAI17959.1|  903|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 903

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 225 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 269


>AL356299-3|CAI17960.1|  862|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 862

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 184 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 228


>AL109923-6|CAI21458.1|  903|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 903

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 225 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 269


>AL109923-5|CAI21459.1|  862|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 862

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 184 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 228


>AF095745-1|AAK39399.1|  862|Homo sapiens ubiquitin protein ligase
           ITCH protein.
          Length = 862

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 184 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 228


>AF038564-1|AAC04845.1|  739|Homo sapiens atrophin-1 interacting
           protein 4 protein.
          Length = 739

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 61  EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 105


>AB056663-1|BAB39389.1|  862|Homo sapiens ubiquitin protein ligase
           Itch protein.
          Length = 862

 Score = 30.3 bits (65), Expect = 2.8
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +2

Query: 260 EDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILTPKPRRPSS 400
           EDA  G    VSG +S     +   + P R P P     P PRRP+S
Sbjct: 184 EDAGAGENRRVSGNNSPS--LSNGGFKPSRPPRPSRPPPPTPRRPAS 228


>U77457-1|AAC13544.1|  161|Homo sapiens LIM-homeodomain protein
           LMX1B/LMX1.2 protein.
          Length = 161

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 52  YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 110

Query: 377 PKPRR 391
            + RR
Sbjct: 111 TQQRR 115


>BC113491-1|AAI13492.1|  372|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 372

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>BC112120-1|AAI12121.1|  372|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 372

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>BC069601-1|AAH69601.1|  372|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 372

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>BC069588-1|AAH69588.1|  377|Homo sapiens LMX1B protein protein.
          Length = 377

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 144 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 202

Query: 377 PKPRR 391
            + RR
Sbjct: 203 TQQRR 207


>AL161908-2|CAH70295.1|  372|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 372

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>AL161908-1|CAH70294.1|  402|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 402

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 169 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 227

Query: 377 PKPRR 391
            + RR
Sbjct: 228 TQQRR 232


>AL161731-2|CAI40918.1|  372|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 372

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>AL161731-1|CAI40917.1|  402|Homo sapiens LIM homeobox transcription
           factor 1, beta protein.
          Length = 402

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 169 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 227

Query: 377 PKPRR 391
            + RR
Sbjct: 228 TQQRR 232


>AF059575-1|AAC27294.1|  379|Homo sapiens LIM homeodomain protein
           protein.
          Length = 379

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>AF057135-1|AAC39738.1|  372|Homo sapiens LIM homeodomain protein
           LMX1B protein.
          Length = 372

 Score = 29.5 bits (63), Expect = 4.9
 Identities = 21/65 (32%), Positives = 26/65 (40%)
 Frame = +2

Query: 197 YDVEKQFCVPVCALSVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEILT 376
           Y+ EK     V     + + SED  G    A  G  S+  G       PRR   P  ILT
Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPA-KGQGSQSKGSGDDGKDPRRPKRPRTILT 204

Query: 377 PKPRR 391
            + RR
Sbjct: 205 TQQRR 209


>AK055759-1|BAB71005.1|  171|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31197 fis, clone KIDNE2000519, weakly similar to
           TONB PROTEIN. ).
          Length = 171

 Score = 29.1 bits (62), Expect = 6.5
 Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 3/49 (6%)
 Frame = -1

Query: 402 PLEGLLGFGVRISCGAGCRRGDHAVQAQPCS---RESPPLTASARPPHA 265
           P   L G G +  C  GCR G  A     C    R++P L A  + P A
Sbjct: 16  PPRKLSGLGSKQVCSRGCRLGHLAAPGAACMLPWRQAPGLVARRQSPKA 64


>AB037158-1|BAA96867.1|  190|Homo sapiens DSCR6a protein.
          Length = 190

 Score = 29.1 bits (62), Expect = 6.5
 Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
 Frame = +2

Query: 284 EAVSGG-DSREHGCACTAWSPRRQPAPHEILTPKPRRP 394
           EA +G   +R  GC C   +P R P P    +P P RP
Sbjct: 4   EAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRP 41


>U94190-1|AAC15791.1| 1663|Homo sapiens Duo protein.
          Length = 1663

 Score = 28.7 bits (61), Expect = 8.5
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +2

Query: 188  VCFYDVEKQFCVPVCALSVECMASEDACGGR 280
            V FY   +Q C  + +L  E    ED CGGR
Sbjct: 1006 VAFYKTSEQVCSVLESLEQEYRRDEDWCGGR 1036


>AL354991-1|CAO03638.1|  645|Homo sapiens WNK lysine deficient
           protein kinase 2 protein.
          Length = 645

 Score = 28.7 bits (61), Expect = 8.5
 Identities = 15/45 (33%), Positives = 21/45 (46%)
 Frame = +2

Query: 239 SVECMASEDACGGRAEAVSGGDSREHGCACTAWSPRRQPAPHEIL 373
           SV    S D C G A    GG +R  G + ++ +P  +P P   L
Sbjct: 536 SVRASLSSDICSGLAS--DGGGARGQGSSTSSLAPGPEPGPQPAL 578


>AK131379-1|BAD18530.1|  851|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16443 fis, clone BRAMY3004800, highly  similar
           to Huntingtin-associated protein-interacting protein. ).
          Length = 851

 Score = 28.7 bits (61), Expect = 8.5
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +2

Query: 188 VCFYDVEKQFCVPVCALSVECMASEDACGGR 280
           V FY   +Q C  + +L  E    ED CGGR
Sbjct: 352 VAFYKTSEQVCSVLESLEQEYRRDEDWCGGR 382


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,223,294
Number of Sequences: 237096
Number of extensions: 1062224
Number of successful extensions: 3558
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 3370
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3552
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3259265358
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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