Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-6390
(737 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 54 4e-07
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 54 4e-07
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 54 4e-07
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 54 4e-07
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 54 4e-07
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 54 4e-07
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 46 1e-04
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 46 1e-04
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 46 1e-04
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 46 1e-04
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 46 1e-04
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 46 1e-04
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 43 0.001
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = +3
Query: 393 PKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVR 572
P F AK + + V + + ++ DESY L + A ++ N +G
Sbjct: 115 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV-----AVLKANRVWGAL 169
Query: 573 HGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
GLET SQL+ D + + TI D P + +RGIL+DT+R++ ++ I +T
Sbjct: 170 RGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKT 222
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = +3
Query: 393 PKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVR 572
P F AK + + V + + ++ DESY L + A ++ N +G
Sbjct: 103 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV-----AVLKANRVWGAL 157
Query: 573 HGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
GLET SQL+ D + + TI D P + +RGIL+DT+R++ ++ I +T
Sbjct: 158 RGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKT 210
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = +3
Query: 393 PKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVR 572
P F AK + + V + + ++ DESY L + A ++ N +G
Sbjct: 131 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV-----AVLKANRVWGAL 185
Query: 573 HGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
GLET SQL+ D + + TI D P + +RGIL+DT+R++ ++ I +T
Sbjct: 186 RGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKT 238
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = +3
Query: 393 PKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVR 572
P F AK + + V + + ++ DESY L + A ++ N +G
Sbjct: 115 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV-----AVLKANRVWGAL 169
Query: 573 HGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
GLET SQL+ D + + TI D P + +RGIL+DT+R++ ++ I +T
Sbjct: 170 RGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKT 222
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = +3
Query: 393 PKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVR 572
P F AK + + V + + ++ DESY L + A ++ N +G
Sbjct: 115 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV-----AVLKANRVWGAL 169
Query: 573 HGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
GLET SQL+ D + + TI D P + +RGIL+DT+R++ ++ I +T
Sbjct: 170 RGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKT 222
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = +3
Query: 393 PKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVR 572
P F AK + + V + + ++ DESY L + A ++ N +G
Sbjct: 115 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPV-----AVLKANRVWGAL 169
Query: 573 HGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
GLET SQL+ D + + TI D P + +RGIL+DT+R++ ++ I +T
Sbjct: 170 RGLETFSQLVYQDSY--GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKT 222
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +3
Query: 489 ESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPV 668
ES E Y + + D+ + + +G GLET SQL+ + I+D P
Sbjct: 111 ESVENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPR 166
Query: 669 YPYRGILLDTARNFYSIESIKRT 737
+P+RG+LLDT+R++ + SI T
Sbjct: 167 FPHRGLLLDTSRHYLPLSSILDT 189
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +3
Query: 489 ESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPV 668
ES E Y + + D+ + + +G GLET SQL+ + I+D P
Sbjct: 111 ESVENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPR 166
Query: 669 YPYRGILLDTARNFYSIESIKRT 737
+P+RG+LLDT+R++ + SI T
Sbjct: 167 FPHRGLLLDTSRHYLPLSSILDT 189
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +3
Query: 489 ESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPV 668
ES E Y + + D+ + + +G GLET SQL+ + I+D P
Sbjct: 72 ESVENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPR 127
Query: 669 YPYRGILLDTARNFYSIESIKRT 737
+P+RG+LLDT+R++ + SI T
Sbjct: 128 FPHRGLLLDTSRHYLPLSSILDT 150
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +3
Query: 489 ESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPV 668
ES E Y + + D+ + + +G GLET SQL+ + I+D P
Sbjct: 111 ESVENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPR 166
Query: 669 YPYRGILLDTARNFYSIESIKRT 737
+P+RG+LLDT+R++ + SI T
Sbjct: 167 FPHRGLLLDTSRHYLPLSSILDT 189
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +3
Query: 489 ESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPV 668
ES E Y + + D+ + + +G GLET SQL+ + I+D P
Sbjct: 111 ESVENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPR 166
Query: 669 YPYRGILLDTARNFYSIESIKRT 737
+P+RG+LLDT+R++ + SI T
Sbjct: 167 FPHRGLLLDTSRHYLPLSSILDT 189
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +3
Query: 489 ESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPV 668
ES E Y + + D+ + + +G GLET SQL+ + I+D P
Sbjct: 111 ESVENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPR 166
Query: 669 YPYRGILLDTARNFYSIESIKRT 737
+P+RG+LLDT+R++ + SI T
Sbjct: 167 FPHRGLLLDTSRHYLPLSSILDT 189
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/59 (37%), Positives = 33/59 (55%)
Frame = +3
Query: 561 FGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRT 737
+G GLET SQL+ + I+D P +P+RG+LLDT+R++ + SI T
Sbjct: 13 WGALRGLETFSQLVWKS--AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDT 69
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,190,438
Number of Sequences: 237096
Number of extensions: 2298975
Number of successful extensions: 4748
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4494
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4721
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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