Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-6305
(826 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 213 7e-55
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 213 7e-55
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 210 6e-54
AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase ... 158 3e-38
U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein. 155 2e-37
U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein. 155 2e-37
U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein. 155 2e-37
U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein. 155 2e-37
U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein. 155 2e-37
M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase pr... 155 2e-37
BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L2 protein protein. 155 2e-37
BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L2 protein protein. 155 2e-37
BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein. 155 2e-37
AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3 p... 155 2e-37
AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase ... 155 2e-37
AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase ... 155 2e-37
M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein. 153 7e-37
AB209829-1|BAD93066.1| 214|Homo sapiens cyclin-dependent kinase... 153 7e-37
BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-l... 153 1e-36
BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein. 153 1e-36
BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein. 153 1e-36
AL031282-7|CAI20033.1| 770|Homo sapiens cell division cycle 2-l... 153 1e-36
AL031282-6|CAI20032.1| 783|Homo sapiens cell division cycle 2-l... 153 1e-36
AL031282-5|CAI20034.1| 780|Homo sapiens cell division cycle 2-l... 153 1e-36
AL031282-4|CAI20031.1| 779|Homo sapiens cell division cycle 2-l... 153 1e-36
AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-l... 153 1e-36
AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase ... 153 1e-36
AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase ... 153 1e-36
U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22 p... 151 3e-36
U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21 p... 151 3e-36
U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein. 151 3e-36
AF067525-1|AAC72090.1| 528|Homo sapiens PITSLRE protein kinase ... 147 5e-35
BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein. 146 8e-35
BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein. 146 8e-35
BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein. 122 2e-27
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 122 2e-27
X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein ... 120 5e-27
L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein. 120 5e-27
BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase... 120 5e-27
AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase... 120 5e-27
AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase... 120 5e-27
AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9 pro... 120 5e-27
BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase... 120 6e-27
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 119 1e-26
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 119 1e-26
BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein. 119 1e-26
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 119 1e-26
M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kina... 118 2e-26
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 118 3e-26
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 115 2e-25
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 115 2e-25
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 115 2e-25
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 115 2e-25
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 115 2e-25
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 111 3e-24
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 111 3e-24
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 109 2e-23
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 107 6e-23
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 107 6e-23
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 107 6e-23
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 107 6e-23
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 105 1e-22
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 101 2e-21
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 101 2e-21
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 101 2e-21
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 101 2e-21
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 101 2e-21
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 101 2e-21
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 101 4e-21
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 100 7e-21
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 97 7e-20
DQ411039-1|ABD66016.1| 260|Homo sapiens protein kinase CDK5 spl... 95 3e-19
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 94 6e-19
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 94 6e-19
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 94 6e-19
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 94 6e-19
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 94 6e-19
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 94 6e-19
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 94 6e-19
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 92 2e-18
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 92 2e-18
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 92 2e-18
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 92 2e-18
D88357-1|BAA26001.1| 240|Homo sapiens CDC2 delta T protein. 91 3e-18
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 91 3e-18
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 91 3e-18
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 91 3e-18
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 91 6e-18
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 90 8e-18
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 90 8e-18
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 90 8e-18
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 90 1e-17
AL357131-3|CAH72011.1| 280|Homo sapiens PCTAIRE protein kinase ... 89 2e-17
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 88 3e-17
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 88 3e-17
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 88 3e-17
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 88 3e-17
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 88 3e-17
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 88 3e-17
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 88 3e-17
AC072061-2|AAS07490.1| 170|Homo sapiens unknown protein. 88 3e-17
AC072061-1|AAS07491.1| 784|Homo sapiens unknown protein. 88 3e-17
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 88 4e-17
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 87 6e-17
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 87 6e-17
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 87 6e-17
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 87 6e-17
AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kina... 85 2e-16
AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kina... 85 2e-16
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 85 3e-16
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 85 3e-16
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 85 3e-16
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 84 7e-16
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 84 7e-16
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 84 7e-16
AL357131-2|CAH72010.1| 282|Homo sapiens PCTAIRE protein kinase ... 84 7e-16
BC002655-1|AAH02655.1| 275|Homo sapiens CCRK protein protein. 83 9e-16
AY904367-1|AAW82349.1| 243|Homo sapiens cell cycle-related kina... 83 9e-16
AL353572-5|CAH72843.1| 325|Homo sapiens cell cycle related kina... 83 9e-16
AF113130-1|AAF43778.1| 452|Homo sapiens cyclin-dependent protei... 83 1e-15
AF035013-1|AAC98920.1| 452|Homo sapiens cell cycle related kina... 83 1e-15
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 81 6e-15
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 79 1e-14
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 79 1e-14
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 77 1e-13
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 77 1e-13
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 77 1e-13
AK131486-1|BAD18631.1| 356|Homo sapiens protein ( Homo sapiens ... 77 1e-13
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 77 1e-13
AB209465-1|BAD92702.1| 556|Homo sapiens Hypothetical protein FL... 77 1e-13
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 77 1e-13
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 75 2e-13
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 75 2e-13
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 75 2e-13
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 75 2e-13
BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein. 75 2e-13
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 75 2e-13
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 75 2e-13
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 75 2e-13
AL024498-4|CAB75823.1| 623|Homo sapiens protein ( ovel serine/t... 75 2e-13
AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associat... 75 2e-13
AL162586-8|CAI39767.1| 194|Homo sapiens cyclin-dependent kinase... 75 4e-13
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 74 5e-13
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 74 5e-13
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 74 5e-13
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 74 5e-13
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 74 5e-13
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 74 5e-13
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 74 5e-13
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 74 5e-13
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 74 5e-13
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 74 7e-13
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 74 7e-13
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 74 7e-13
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 74 7e-13
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 74 7e-13
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 73 2e-12
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 73 2e-12
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 73 2e-12
AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase ... 73 2e-12
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 72 2e-12
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 72 2e-12
M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein. 72 2e-12
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 72 2e-12
BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated prote... 72 2e-12
X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine ... 72 3e-12
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 72 3e-12
AY033608-1|AAK52330.1| 335|Homo sapiens extracellular signal-re... 72 3e-12
AY033607-1|AAK52329.1| 357|Homo sapiens extracellular signal-re... 72 3e-12
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 72 3e-12
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 71 4e-12
Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-lik... 71 5e-12
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 71 5e-12
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 71 5e-12
BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein. 71 5e-12
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 71 5e-12
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 71 5e-12
AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase... 71 5e-12
AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-l... 71 5e-12
AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-l... 71 5e-12
AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein. 71 5e-12
X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein. 70 1e-11
BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase... 70 1e-11
BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase... 70 1e-11
BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase... 70 1e-11
BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase... 70 1e-11
AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase... 70 1e-11
AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase... 70 1e-11
AL353572-3|CAM17658.1| 338|Homo sapiens cell cycle related kina... 69 2e-11
AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragmen... 69 2e-11
AY702976-1|AAU29339.1| 164|Homo sapiens cyclin-dependent kinase... 69 3e-11
Z95152-2|CAB08438.1| 365|Homo sapiens mitogen-activated protein... 68 4e-11
Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein ... 68 4e-11
U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein. 68 4e-11
CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein. 68 4e-11
CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein. 68 4e-11
BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated prote... 68 4e-11
BC085196-1|AAH85196.1| 257|Homo sapiens MAPK13 protein protein. 68 4e-11
BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated prote... 68 4e-11
BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated prote... 68 4e-11
BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated prote... 68 4e-11
AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protei... 68 4e-11
AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated prote... 68 4e-11
Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein. 68 5e-11
BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated prote... 68 5e-11
Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase prot... 67 6e-11
M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein. 67 6e-11
DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated prote... 67 6e-11
BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated prote... 67 6e-11
AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated p... 67 8e-11
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 66 1e-10
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 66 1e-10
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 66 1e-10
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 66 1e-10
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 66 1e-10
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 66 1e-10
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 66 1e-10
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 66 1e-10
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 66 1e-10
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 66 1e-10
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 66 1e-10
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 66 1e-10
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 66 1e-10
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 66 1e-10
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 66 1e-10
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 66 1e-10
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 66 1e-10
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 66 1e-10
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 66 1e-10
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 66 2e-10
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 66 2e-10
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 66 2e-10
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 66 2e-10
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 66 2e-10
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 66 2e-10
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 66 2e-10
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 66 2e-10
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 66 2e-10
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 66 2e-10
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 66 2e-10
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 66 2e-10
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 66 2e-10
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 66 2e-10
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 66 2e-10
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 66 2e-10
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 66 2e-10
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 66 2e-10
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 66 2e-10
AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protei... 65 3e-10
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 65 3e-10
U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein ... 64 4e-10
AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein. 64 4e-10
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 64 6e-10
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 64 6e-10
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 64 6e-10
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 64 6e-10
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 64 6e-10
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 64 6e-10
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 64 6e-10
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 64 6e-10
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 64 6e-10
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 63 1e-09
BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein. 63 1e-09
BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein. 63 1e-09
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 62 2e-09
S67448-1|AAD13991.1| 89|Homo sapiens CDK4 protein. 62 2e-09
AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens ... 62 2e-09
EF644172-1|ABR45718.1| 433|Homo sapiens polarization-related pr... 62 2e-09
Z95152-5|CAO03649.1| 360|Homo sapiens mitogen-activated protein... 62 3e-09
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 62 3e-09
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 62 3e-09
L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein pr... 62 3e-09
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 62 3e-09
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 62 3e-09
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 62 3e-09
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 62 3e-09
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 62 3e-09
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 62 3e-09
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 62 3e-09
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 62 3e-09
AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1 pro... 62 3e-09
AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced var... 62 3e-09
BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein. 61 4e-09
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 61 4e-09
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 61 4e-09
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 61 4e-09
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 61 4e-09
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 61 4e-09
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 61 4e-09
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 61 4e-09
AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase prot... 61 4e-09
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 60 7e-09
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 60 7e-09
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 60 7e-09
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 60 7e-09
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 60 7e-09
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 60 7e-09
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 60 7e-09
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 60 7e-09
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 60 7e-09
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 60 7e-09
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 60 7e-09
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 60 7e-09
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 60 7e-09
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 60 7e-09
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 60 7e-09
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 60 7e-09
Z95152-3|CAI19690.1| 355|Homo sapiens mitogen-activated protein... 60 1e-08
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 60 1e-08
AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens ... 60 1e-08
X62048-1|CAA43979.1| 646|Homo sapiens Wee1 Hu protein. 60 1e-08
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 60 1e-08
U10564-1|AAB60401.1| 646|Homo sapiens WEE1Hu CDK tyrosine 15-ki... 60 1e-08
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 60 1e-08
BC070052-1|AAH70052.1| 646|Homo sapiens WEE1 homolog (S. pombe)... 60 1e-08
AJ277546-2|CAC14173.1| 646|Homo sapiens WEE1 protein protein. 60 1e-08
AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 59 2e-08
AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 59 2e-08
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 59 2e-08
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 59 2e-08
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 59 2e-08
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 58 3e-08
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 58 3e-08
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 58 3e-08
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 58 3e-08
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 58 3e-08
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 58 4e-08
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 58 4e-08
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 58 5e-08
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 58 5e-08
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 58 5e-08
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 57 7e-08
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 57 7e-08
BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein. 57 7e-08
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 57 7e-08
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 57 7e-08
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 57 7e-08
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 57 7e-08
AB209586-1|BAD92823.1| 255|Homo sapiens mitogen-activated prote... 57 7e-08
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 57 7e-08
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 57 7e-08
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 57 7e-08
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 56 1e-07
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 56 1e-07
BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein pr... 56 1e-07
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 56 1e-07
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 56 1e-07
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 56 1e-07
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 56 1e-07
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 56 1e-07
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 56 1e-07
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 56 1e-07
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 56 1e-07
BC006524-1|AAH06524.1| 630|Homo sapiens eukaryotic translation ... 56 1e-07
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 56 1e-07
AK075192-1|BAC11461.1| 630|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 56 1e-07
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 56 1e-07
AF255050-1|AAF70289.1| 629|Homo sapiens heme-regulated eukaryot... 56 1e-07
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 56 1e-07
AF183414-1|AAG09683.1| 630|Homo sapiens hemin-sensitive initiat... 56 1e-07
AF147094-1|AAF66736.1| 629|Homo sapiens heme-regulated initiati... 56 1e-07
AF100784-1|AAP97223.1| 630|Homo sapiens hemin-sensitive initita... 56 1e-07
AC004895-3|AAS00356.1| 243|Homo sapiens unknown protein. 56 1e-07
AC002065-1|AAM48566.1| 58|Homo sapiens unknown protein. 56 1e-07
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 56 1e-07
AB037790-1|BAA92607.1| 653|Homo sapiens KIAA1369 protein protein. 56 1e-07
AF181071-1|AAF18391.1| 630|Homo sapiens heme-regulated initiati... 56 2e-07
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 56 2e-07
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 56 2e-07
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 56 2e-07
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 56 2e-07
L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein. 56 2e-07
CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein. 56 2e-07
BC051831-1|AAH51831.1| 646|Homo sapiens WEE1 homolog (S. pombe)... 56 2e-07
BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein. 56 2e-07
BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinas... 56 2e-07
AF390028-1|AAL58838.1| 993|Homo sapiens serine/threonine protei... 56 2e-07
CR456515-1|CAG30401.1| 357|Homo sapiens MAPK12 protein. 55 3e-07
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 55 4e-07
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 55 4e-07
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 55 4e-07
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 55 4e-07
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 55 4e-07
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 55 4e-07
BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated prote... 55 4e-07
BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated prote... 55 4e-07
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 55 4e-07
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 55 4e-07
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 55 4e-07
AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated prote... 55 4e-07
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 54 5e-07
BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein. 54 5e-07
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 54 5e-07
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 54 5e-07
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 54 6e-07
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 54 6e-07
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 54 6e-07
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 54 6e-07
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 54 6e-07
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 54 6e-07
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 54 6e-07
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 54 6e-07
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 54 6e-07
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 54 6e-07
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 54 6e-07
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 54 6e-07
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 54 6e-07
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 53 1e-06
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 53 1e-06
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 53 1e-06
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 53 1e-06
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 53 1e-06
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 53 1e-06
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 53 1e-06
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 52 2e-06
U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase... 52 2e-06
U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase... 52 2e-06
U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinas... 52 2e-06
U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinas... 52 2e-06
U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinas... 52 2e-06
U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein. 52 2e-06
L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein. 52 2e-06
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 52 2e-06
DQ234352-1|ABB29981.1| 308|Homo sapiens mitogen-activated prote... 52 2e-06
BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated prote... 52 2e-06
BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated prote... 52 2e-06
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 52 2e-06
BC065516-1|AAH65516.1| 319|Homo sapiens MAPK10 protein protein. 52 2e-06
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 52 2e-06
BC051731-1|AAH51731.1| 319|Homo sapiens MAPK10 protein protein. 52 2e-06
BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein. 52 2e-06
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 52 2e-06
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 52 2e-06
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
AY283670-1|AAP57089.1| 292|Homo sapiens interleukin-1 receptor ... 52 2e-06
AL603914-3|CAI41173.1| 251|Homo sapiens cell division cycle 2-l... 52 2e-06
AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-l... 52 2e-06
AL512430-2|CAI40283.1| 251|Homo sapiens cell division cycle 2-l... 52 2e-06
AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-l... 52 2e-06
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 52 2e-06
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 52 2e-06
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 52 2e-06
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 52 2e-06
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 52 2e-06
AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit... 52 2e-06
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 52 2e-06
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 52 2e-06
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 52 2e-06
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 52 2e-06
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 52 2e-06
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 52 3e-06
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 52 3e-06
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 52 3e-06
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 52 3e-06
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 52 3e-06
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 52 3e-06
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 52 3e-06
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 52 3e-06
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 52 3e-06
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 52 3e-06
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 52 3e-06
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 52 3e-06
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 52 3e-06
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 52 3e-06
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 52 3e-06
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 52 3e-06
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 52 3e-06
>X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein.
Length = 360
Score = 213 bits (520), Expect = 7e-55
Identities = 110/208 (52%), Positives = 139/208 (66%)
Frame = +2
Query: 203 IPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSG 382
+P + LG+CR V EFEKLNRIGEGTYGIVYRA++ IVALKKVRMD EKDG+P+S
Sbjct: 24 VPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISS 83
Query: 383 LREIQVLMSCRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCL 562
LREI +L+ RH NIV+LKEV+VG LESIFL M YCEQDLASLL+NM +PF+E+QVKC+
Sbjct: 84 LREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCI 143
Query: 563 MLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLM 742
+LQVL+GL+YLH NF L+ + + F + P + L
Sbjct: 144 VLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLW 203
Query: 743 V*GARILLQSPRQTPALDMWAAGCILGD 826
+LL + QT ++DMWA GCIL +
Sbjct: 204 YRAPELLLGTTTQTTSIDMWAVGCILAE 231
Score = 91.9 bits (218), Expect = 3e-18
Identities = 40/51 (78%), Positives = 44/51 (86%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
FI+HRDLKVSNLL+TDKGCVK ADFGLAR G P + TP+VVTLWYRAPE
Sbjct: 158 FIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 208
>AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase
protein.
Length = 360
Score = 213 bits (520), Expect = 7e-55
Identities = 110/208 (52%), Positives = 139/208 (66%)
Frame = +2
Query: 203 IPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSG 382
+P + LG+CR V EFEKLNRIGEGTYGIVYRA++ IVALKKVRMD EKDG+P+S
Sbjct: 24 VPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISS 83
Query: 383 LREIQVLMSCRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCL 562
LREI +L+ RH NIV+LKEV+VG LESIFL M YCEQDLASLL+NM +PF+E+QVKC+
Sbjct: 84 LREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCI 143
Query: 563 MLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLM 742
+LQVL+GL+YLH NF L+ + + F + P + L
Sbjct: 144 VLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLW 203
Query: 743 V*GARILLQSPRQTPALDMWAAGCILGD 826
+LL + QT ++DMWA GCIL +
Sbjct: 204 YRAPELLLGTTTQTTSIDMWAVGCILAE 231
Score = 91.9 bits (218), Expect = 3e-18
Identities = 40/51 (78%), Positives = 44/51 (86%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
FI+HRDLKVSNLL+TDKGCVK ADFGLAR G P + TP+VVTLWYRAPE
Sbjct: 158 FIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 208
>L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kinase
protein.
Length = 314
Score = 210 bits (512), Expect = 6e-54
Identities = 108/202 (53%), Positives = 136/202 (67%)
Frame = +2
Query: 221 LGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQV 400
+G+CR V EFEKLNRIGEGTYGIVYRA++ IVALKKVRMD EKDG+P+S LREI +
Sbjct: 1 MGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITL 60
Query: 401 LMSCRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLK 580
L+ RH NIV+LKEV+VG LESIFL M YCEQDLASLL+NM +PF+E+QVKC++LQVL+
Sbjct: 61 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLR 120
Query: 581 GLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARI 760
GL+YLH NF L+ + + F + P + L +
Sbjct: 121 GLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPEL 180
Query: 761 LLQSPRQTPALDMWAAGCILGD 826
LL + QT ++DMWA GCIL +
Sbjct: 181 LLGTTTQTTSIDMWAVGCILAE 202
Score = 91.9 bits (218), Expect = 3e-18
Identities = 40/51 (78%), Positives = 44/51 (86%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
FI+HRDLKVSNLL+TDKGCVK ADFGLAR G P + TP+VVTLWYRAPE
Sbjct: 129 FIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 179
>AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase alpha
SV9 isoform protein.
Length = 755
Score = 158 bits (383), Expect = 3e-38
Identities = 88/247 (35%), Positives = 139/247 (56%)
Frame = +2
Query: 86 KRMSQGSEKSASNHDVVDPTGPGTRKGVLISFRTGKTMEIPEKDILGKCRFVGEFEKLNR 265
+ MS+ E+ NH +V P R +G++ E E+ CR V EF+ LNR
Sbjct: 355 EEMSEDEERENENHLLVVPESRFDRD-------SGESEEAEEEG----CRSVEEFQCLNR 403
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
I EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++ +H NIV ++E+
Sbjct: 404 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 463
Query: 446 LVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA*GL 625
+VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K+LH N+ L
Sbjct: 464 VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDL 523
Query: 626 EGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPALDMWA 805
+ + + + F + P + L +LL + + A+DMW+
Sbjct: 524 KTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWS 583
Query: 806 AGCILGD 826
GCI G+
Sbjct: 584 VGCIFGE 590
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 517 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 567
>U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein.
Length = 779
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 416 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 475
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 476 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 535
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 536 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 595
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 596 AKEYSTAVDMWSVGCIFGE 614
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 541 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 591
>U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein.
Length = 562
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 199 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 258
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 259 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 318
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 319 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 378
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 379 AKEYSTAVDMWSVGCIFGE 397
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 324 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 374
>U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein.
Length = 768
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 405 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 464
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 465 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 524
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 525 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 584
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 585 AKEYSTAVDMWSVGCIFGE 603
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 530 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 580
>U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein.
Length = 777
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 414 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 473
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 474 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 593
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 594 AKEYSTAVDMWSVGCIFGE 612
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 539 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 589
>U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein.
Length = 461
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 98 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 157
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 158 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 217
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 218 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 277
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 278 AKEYSTAVDMWSVGCIFGE 296
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 223 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 273
>M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase
protein.
Length = 439
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 76 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 135
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 136 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 195
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 196 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 255
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 256 AKEYSTAVDMWSVGCIFGE 274
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 201 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 251
>BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L2 protein protein.
Length = 542
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 179 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 238
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 239 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 298
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 299 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 358
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 359 AKEYSTAVDMWSVGCIFGE 377
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 304 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 354
>BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L2 protein protein.
Length = 475
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 112 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 171
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 172 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 231
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 232 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 291
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 292 AKEYSTAVDMWSVGCIFGE 310
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 237 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 287
>BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein.
Length = 508
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 145 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 204
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 205 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 264
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 265 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 324
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 325 AKEYSTAVDMWSVGCIFGE 343
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 270 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 320
>AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3
protein.
Length = 565
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 202 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 261
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 262 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 321
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 322 HLHDNWILQRDLKTSTLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 381
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 382 AKEYSTAVDMWSVGCIFGE 400
Score = 68.9 bits (161), Expect = 2e-11
Identities = 31/51 (60%), Positives = 39/51 (76%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+ RDLK S LLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 327 WILQRDLKTSTLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 377
>AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 202 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 261
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 262 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 321
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 322 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 381
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 382 AKEYSTAVDMWSVGCIFGE 400
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 327 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 377
>AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 738
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 375 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 434
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 435 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 494
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 495 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 554
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 555 AKEYSTAVDMWSVGCIFGE 573
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 500 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 550
>AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 385 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 444
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 445 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 504
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 505 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 564
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 565 AKEYSTAVDMWSVGCIFGE 583
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 510 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 560
>AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase alpha
SV1 isoform protein.
Length = 782
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 419 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 478
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 479 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 538
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 539 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 598
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 599 AKEYSTAVDMWSVGCIFGE 617
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 544 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 594
>AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 202 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 261
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 262 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 321
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 322 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 381
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 382 AKEYSTAVDMWSVGCIFGE 400
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 327 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 377
>AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 385 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 444
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 445 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 504
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 505 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 564
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 565 AKEYSTAVDMWSVGCIFGE 583
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 510 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 560
>AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase alpha
SV9 isoform protein.
Length = 795
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 432 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 491
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 492 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 551
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 552 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 611
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 612 AKEYSTAVDMWSVGCIFGE 630
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 557 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 607
>AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 737
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 374 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 433
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 434 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 493
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 494 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 553
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 554 AKEYSTAVDMWSVGCIFGE 572
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 499 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 549
>AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase
alpha SV4 isoform protein.
Length = 526
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 163 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 222
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 223 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 282
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 283 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 342
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 343 AKEYSTAVDMWSVGCIFGE 361
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 288 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 338
>AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase alpha
SV1 isoform protein.
Length = 782
Score = 155 bits (376), Expect = 2e-37
Identities = 77/199 (38%), Positives = 120/199 (60%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 419 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 478
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 479 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 538
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + L +LL
Sbjct: 539 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 598
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 599 AKEYSTAVDMWSVGCIFGE 617
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVTLWYRAPE
Sbjct: 544 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPE 594
>M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein.
Length = 446
Score = 153 bits (371), Expect = 7e-37
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 83 CRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 142
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 143 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 202
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 203 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 262
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 263 AKEYSTAVDMWSVGCIFGE 281
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 208 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 258
>AB209829-1|BAD93066.1| 214|Homo sapiens cyclin-dependent kinase 10
isoform 3 variant protein.
Length = 214
Score = 153 bits (371), Expect = 7e-37
Identities = 73/111 (65%), Positives = 89/111 (80%)
Frame = +2
Query: 275 GTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEVLVG 454
G G RA++ IVALKKVRMD EKDG+P+S LREI +L+ RH NIV+LKEV+VG
Sbjct: 6 GASGTQDRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVG 65
Query: 455 RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNF 607
LESIFL M YCEQDLASLL+NM +PF+E+QVKC++LQVL+GL+YLH NF
Sbjct: 66 NHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNF 116
Score = 46.4 bits (105), Expect = 1e-04
Identities = 19/21 (90%), Positives = 21/21 (100%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVK 668
FI+HRDLKVSNLL+TDKGCVK
Sbjct: 116 FIIHRDLKVSNLLMTDKGCVK 136
>BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 397
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 34 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 93
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 94 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 153
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 154 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 213
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 214 AKEYSTAVDMWSVGCIFGE 232
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 159 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 209
>BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein.
Length = 475
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 112 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 171
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 172 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 231
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 232 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 291
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 292 AKEYSTAVDMWSVGCIFGE 310
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 237 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 287
>BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein.
Length = 464
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 101 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 160
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 161 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 220
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 221 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 280
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 281 AKEYSTAVDMWSVGCIFGE 299
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 226 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 276
>AL031282-7|CAI20033.1| 770|Homo sapiens cell division cycle 2-like 2
(PITSLRE proteins) protein.
Length = 770
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 407 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 466
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 467 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 526
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 527 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 586
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 587 AKEYSTAVDMWSVGCIFGE 605
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 532 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 582
>AL031282-6|CAI20032.1| 783|Homo sapiens cell division cycle 2-like 2
(PITSLRE proteins) protein.
Length = 783
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 420 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 479
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 480 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 539
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 540 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 599
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 600 AKEYSTAVDMWSVGCIFGE 618
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 545 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 595
>AL031282-5|CAI20034.1| 780|Homo sapiens cell division cycle 2-like 2
(PITSLRE proteins) protein.
Length = 780
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 596
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 597 AKEYSTAVDMWSVGCIFGE 615
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 542 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 592
>AL031282-4|CAI20031.1| 779|Homo sapiens cell division cycle 2-like 2
(PITSLRE proteins) protein.
Length = 779
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 416 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 475
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 476 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 535
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 536 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 595
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 596 AKEYSTAVDMWSVGCIFGE 614
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 541 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 591
>AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 746
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 383 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 442
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 443 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 502
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 562
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 563 AKEYSTAVDMWSVGCIFGE 581
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 508 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 558
>AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase beta
SV3 isoform protein.
Length = 768
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 405 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 464
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 465 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 524
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 525 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 584
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 585 AKEYSTAVDMWSVGCIFGE 603
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 530 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 580
>AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase beta
SV6 isoform protein.
Length = 781
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 418 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 477
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 478 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 537
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 538 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 597
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 598 AKEYSTAVDMWSVGCIFGE 616
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 543 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 593
>AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase beta
SV2 isoform protein.
Length = 777
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 414 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 473
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 474 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 593
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 594 AKEYSTAVDMWSVGCIFGE 612
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 539 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 589
>AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase beta
SV1 isoform protein.
Length = 778
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 415 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 474
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 475 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 534
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 535 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 594
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 595 AKEYSTAVDMWSVGCIFGE 613
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 540 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 590
>AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase
beta SV7 isoform protein.
Length = 397
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 34 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 93
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 94 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 153
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 154 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 213
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 214 AKEYSTAVDMWSVGCIFGE 232
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 159 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 209
>AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase beta
SV6 isoform protein.
Length = 780
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 596
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 597 AKEYSTAVDMWSVGCIFGE 615
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 542 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 592
>AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase beta
SV3 isoform protein.
Length = 767
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 404 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 463
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 464 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 523
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 524 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 583
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 584 AKEYSTAVDMWSVGCIFGE 602
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 529 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 579
>AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase beta
SV2 isoform protein.
Length = 776
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 413 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 472
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 473 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 532
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 533 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 592
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 593 AKEYSTAVDMWSVGCIFGE 611
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 538 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 588
>AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase beta
SV1 isoform protein.
Length = 777
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 414 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 473
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 474 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 593
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 594 AKEYSTAVDMWSVGCIFGE 612
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 539 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 589
>AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase
beta SV8 isoform protein.
Length = 397
Score = 153 bits (370), Expect = 1e-36
Identities = 76/199 (38%), Positives = 119/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 34 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 93
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 94 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 153
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 154 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 213
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 214 AKEYSTAVDMWSVGCIFGE 232
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 159 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 209
>U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22
protein.
Length = 775
Score = 151 bits (366), Expect = 3e-36
Identities = 75/199 (37%), Positives = 118/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ E +G P++ LREI ++
Sbjct: 412 CRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILK 471
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 472 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 531
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 532 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 591
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 592 AKEYSTAVDMWSVGCIFGE 610
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 537 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 587
>U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21
protein.
Length = 777
Score = 151 bits (366), Expect = 3e-36
Identities = 75/199 (37%), Positives = 118/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ E +G P++ LREI ++
Sbjct: 414 CRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILK 473
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 474 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 593
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 594 AKEYSTAVDMWSVGCIFGE 612
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 539 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 589
>U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein.
Length = 439
Score = 151 bits (366), Expect = 3e-36
Identities = 75/199 (37%), Positives = 118/199 (59%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ E +G P++ LREI ++
Sbjct: 76 CRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILK 135
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 136 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 195
Query: 590 YLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
+LH N+ L+ + + + F + P + +LL
Sbjct: 196 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 255
Query: 770 SPRQTPALDMWAAGCILGD 826
+ + A+DMW+ GCI G+
Sbjct: 256 AKEYSTAVDMWSVGCIFGE 274
Score = 72.1 bits (169), Expect = 2e-12
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK SNLLL+ G +K+ DFGLAR G+P ++ TP VVT WYRAPE
Sbjct: 201 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 251
>AF067525-1|AAC72090.1| 528|Homo sapiens PITSLRE protein kinase
beta SV13 isoform protein.
Length = 528
Score = 147 bits (356), Expect = 5e-35
Identities = 63/126 (50%), Positives = 94/126 (74%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
CR V EF+ LNRI EGTYG+VYRAK+K IVALK+++M+ EK+G P++ LREI ++
Sbjct: 356 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 415
Query: 410 CRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLK 589
+H NIV ++E++VG +++ I++ M Y E DL SL++ M PF +VK LM+Q+L+G+K
Sbjct: 416 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 475
Query: 590 YLHSNF 607
+LH N+
Sbjct: 476 HLHDNW 481
Score = 32.3 bits (70), Expect = 2.2
Identities = 13/23 (56%), Positives = 19/23 (82%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIA 674
+I+HRDLK SNLLL+ G +K++
Sbjct: 481 WILHRDLKTSNLLLSHAGILKVS 503
>BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein.
Length = 272
Score = 146 bits (354), Expect = 8e-35
Identities = 77/160 (48%), Positives = 101/160 (63%)
Frame = +2
Query: 347 MDVEKDGLPLSGLREIQVLMSCRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM 526
MD EKDG+P+S LREI +L+ RH NIV+LKEV+VG LESIFL M YCEQDLASLL+NM
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 527 SSPFTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRP 706
+PF+E+QVKC++LQVL+GL+YLH NF L+ + + F + P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 707 GQKCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
+ L +LL + QT ++DMWA GCIL +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAE 160
Score = 91.9 bits (218), Expect = 3e-18
Identities = 40/51 (78%), Positives = 44/51 (86%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
FI+HRDLKVSNLL+TDKGCVK ADFGLAR G P + TP+VVTLWYRAPE
Sbjct: 87 FIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 137
>BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein.
Length = 283
Score = 146 bits (354), Expect = 8e-35
Identities = 77/160 (48%), Positives = 101/160 (63%)
Frame = +2
Query: 347 MDVEKDGLPLSGLREIQVLMSCRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM 526
MD EKDG+P+S LREI +L+ RH NIV+LKEV+VG LESIFL M YCEQDLASLL+NM
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 527 SSPFTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRP 706
+PF+E+QVKC++LQVL+GL+YLH NF L+ + + F + P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 707 GQKCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
+ L +LL + QT ++DMWA GCIL +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAE 160
Score = 91.9 bits (218), Expect = 3e-18
Identities = 40/51 (78%), Positives = 44/51 (86%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
FI+HRDLKVSNLL+TDKGCVK ADFGLAR G P + TP+VVTLWYRAPE
Sbjct: 87 FIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 137
>BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein.
Length = 324
Score = 122 bits (294), Expect = 2e-27
Identities = 74/218 (33%), Positives = 118/218 (54%), Gaps = 9/218 (4%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI R V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 75 ETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 134
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR--SLE------SIFLSMEYCEQDLASLLDNMSSP 535
+REI++L H++I+ +KE++ + +L+ + +L EY + DL LL++
Sbjct: 135 AIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH 194
Query: 536 FTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLV-RRPGQ 712
F E+ +K M Q+++GL Y H ++ N + + F + L +
Sbjct: 195 FNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESR 254
Query: 713 KCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL R TPA+D+W+ GCILG+
Sbjct: 255 PYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 292
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL ++G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 214 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPE 269
>AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-like 5
(cholinesterase-related cell division controller)
protein.
Length = 1512
Score = 122 bits (294), Expect = 2e-27
Identities = 74/218 (33%), Positives = 118/218 (54%), Gaps = 9/218 (4%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI R V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 689 ETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 748
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR--SLE------SIFLSMEYCEQDLASLLDNMSSP 535
+REI++L H++I+ +KE++ + +L+ + +L EY + DL LL++
Sbjct: 749 AIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH 808
Query: 536 FTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLV-RRPGQ 712
F E+ +K M Q+++GL Y H ++ N + + F + L +
Sbjct: 809 FNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESR 868
Query: 713 KCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL R TPA+D+W+ GCILG+
Sbjct: 869 PYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 906
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL ++G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 828 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPE 883
>X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein
kinase protein.
Length = 372
Score = 120 bits (290), Expect = 5e-27
Identities = 74/210 (35%), Positives = 116/210 (55%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*F---RSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + + + F R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G +K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein.
Length = 372
Score = 120 bits (290), Expect = 5e-27
Identities = 74/210 (35%), Positives = 116/210 (55%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*F---RSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + + + F R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G +K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 120 bits (290), Expect = 5e-27
Identities = 74/210 (35%), Positives = 116/210 (55%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*F---RSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + + + F R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G +K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 120 bits (290), Expect = 5e-27
Identities = 74/210 (35%), Positives = 116/210 (55%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*F---RSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + + + F R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G +K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 120 bits (290), Expect = 5e-27
Identities = 74/210 (35%), Positives = 116/210 (55%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*F---RSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + + + F R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G +K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9
protein.
Length = 372
Score = 120 bits (290), Expect = 5e-27
Identities = 74/210 (35%), Positives = 116/210 (55%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*F---RSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + + + F R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G +K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 120 bits (289), Expect = 6e-27
Identities = 74/210 (35%), Positives = 115/210 (54%), Gaps = 11/210 (5%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 410 CRHENIVQLKEVL------VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQ 571
+HEN+V L E+ R SI+L ++CE DLA LL N+ FT S++K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 572 VLKGLKYLHSNFHCA*GLEGVQ---SSFN**RLCQNS*FRSSSLVR--RPGQKCNASCCH 736
+L GL Y+H N ++ + +L R+ SL + +P + N
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVPKLADFGLARAFSLAKNSQPNRYTN-RVVT 191
Query: 737 LMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL P +D+W AGCI+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Score = 58.4 bits (135), Expect = 3e-08
Identities = 30/61 (49%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSA----TPRVVTLWYRAPEYFCSHH 776
I+HRD+K +N+L+T G K+ADFGLAR S T RVVTLWYR PE
Sbjct: 145 ILHRDMKAANVLITRDGVPKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGER 204
Query: 777 D 779
D
Sbjct: 205 D 205
>AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1452
Score = 119 bits (287), Expect = 1e-26
Identities = 73/218 (33%), Positives = 117/218 (53%), Gaps = 9/218 (4%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 689 ETKEKDIDWGKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 748
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR--SLE------SIFLSMEYCEQDLASLLDNMSSP 535
+REI++L H++I+ +KE++ + +L+ + +L EY + DL LL++
Sbjct: 749 AIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH 808
Query: 536 FTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLV-RRPGQ 712
F E+ +K M Q+++GL Y H ++ N + + F + L +
Sbjct: 809 FNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESR 868
Query: 713 KCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL R TPA+D+W+ GCILG+
Sbjct: 869 PYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 906
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL ++G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 828 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPE 883
>AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1512
Score = 119 bits (287), Expect = 1e-26
Identities = 73/218 (33%), Positives = 117/218 (53%), Gaps = 9/218 (4%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 689 ETKEKDIDWGKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 748
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR--SLE------SIFLSMEYCEQDLASLLDNMSSP 535
+REI++L H++I+ +KE++ + +L+ + +L EY + DL LL++
Sbjct: 749 AIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH 808
Query: 536 FTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLV-RRPGQ 712
F E+ +K M Q+++GL Y H ++ N + + F + L +
Sbjct: 809 FNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESR 868
Query: 713 KCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL R TPA+D+W+ GCILG+
Sbjct: 869 PYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 906
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL ++G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 828 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPE 883
>BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein.
Length = 1481
Score = 119 bits (286), Expect = 1e-26
Identities = 78/241 (32%), Positives = 127/241 (52%), Gaps = 9/241 (3%)
Frame = +2
Query: 131 VVDPTGPGTRKGVLISFRTGKTMEIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNK 310
+ P P ++ + R G+ + E D GK R V +F+ + IGEGTYG VY+AK+K
Sbjct: 691 ITPPQQPYKKRPKICCPRYGERRQT-ESD-WGK-RCVDKFDIIGIIGEGTYGQVYKAKDK 747
Query: 311 ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEVLVGR--SLE------ 466
G +VALKKVR+D EK+G P++ +REI++L H ++V +KE++ + +L+
Sbjct: 748 DTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKG 807
Query: 467 SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSF 646
+ +L EY + DL LL++ F+E +K M Q+++GL+Y H ++
Sbjct: 808 AFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 867
Query: 647 N**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILG 823
N + + F + L + L +LL R TPA+D+W+ GCILG
Sbjct: 868 NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 927
Query: 824 D 826
+
Sbjct: 928 E 928
Score = 60.5 bits (140), Expect = 7e-09
Identities = 28/56 (50%), Positives = 38/56 (67%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL + G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 850 CHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPE 905
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 119 bits (286), Expect = 1e-26
Identities = 78/241 (32%), Positives = 127/241 (52%), Gaps = 9/241 (3%)
Frame = +2
Query: 131 VVDPTGPGTRKGVLISFRTGKTMEIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNK 310
+ P P ++ + R G+ + E D GK R V +F+ + IGEGTYG VY+AK+K
Sbjct: 745 ITPPQQPYKKRPKICCPRYGERRQT-ESD-WGK-RCVDKFDIIGIIGEGTYGQVYKAKDK 801
Query: 311 ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEVLVGR--SLE------ 466
G +VALKKVR+D EK+G P++ +REI++L H ++V +KE++ + +L+
Sbjct: 802 DTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKG 861
Query: 467 SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSF 646
+ +L EY + DL LL++ F+E +K M Q+++GL+Y H ++
Sbjct: 862 AFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 921
Query: 647 N**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILG 823
N + + F + L + L +LL R TPA+D+W+ GCILG
Sbjct: 922 NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 981
Query: 824 D 826
+
Sbjct: 982 E 982
Score = 60.5 bits (140), Expect = 7e-09
Identities = 28/56 (50%), Positives = 38/56 (67%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL + G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 904 CHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPE 959
>M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kinase
protein.
Length = 418
Score = 118 bits (285), Expect = 2e-26
Identities = 73/218 (33%), Positives = 117/218 (53%), Gaps = 9/218 (4%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 75 ETKEKDIDWGKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 134
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR--SLE------SIFLSMEYCEQDLASLLDNMSSP 535
+REI++L H++I+ +KE++ + +L+ + +L EY + DL LL++
Sbjct: 135 AIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH 194
Query: 536 FTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLV-RRPGQ 712
F E+ +K M Q+++GL Y H ++ N + + F + L +
Sbjct: 195 FYENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESR 254
Query: 713 KCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILGD 826
L +LL R TPA+D+W+ GCILG+
Sbjct: 255 PYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 292
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL ++G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 214 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPE 269
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 118 bits (283), Expect = 3e-26
Identities = 77/241 (31%), Positives = 127/241 (52%), Gaps = 9/241 (3%)
Frame = +2
Query: 131 VVDPTGPGTRKGVLISFRTGKTMEIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNK 310
+ P P ++ + R G+ + E D GK R V +F+ + IGEGTYG VY+A++K
Sbjct: 691 ITPPQQPYKKRPKICCPRYGERRQT-ESD-WGK-RCVDKFDIIGIIGEGTYGQVYKARDK 747
Query: 311 ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEVLVGR--SLE------ 466
G +VALKKVR+D EK+G P++ +REI++L H ++V +KE++ + +L+
Sbjct: 748 DTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKG 807
Query: 467 SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA*GLEGVQSSF 646
+ +L EY + DL LL++ F+E +K M Q+++GL+Y H ++
Sbjct: 808 AFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 867
Query: 647 N**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSPRQTPALDMWAAGCILG 823
N + + F + L + L +LL R TPA+D+W+ GCILG
Sbjct: 868 NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 927
Query: 824 D 826
+
Sbjct: 928 E 928
Score = 60.5 bits (140), Expect = 7e-09
Identities = 28/56 (50%), Positives = 38/56 (67%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR-WLGAPARSATPRVVTLWYRAPE 758
C +HRD+K SN+LL + G +K+ADFGLAR + +R T +V+TLWYR PE
Sbjct: 850 CHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPE 905
>CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein.
Length = 292
Score = 115 bits (277), Expect = 2e-25
Identities = 68/194 (35%), Positives = 106/194 (54%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL +IGEGTYG V++AKN+ IVALK+VR+D + +G+P S LREI +L +H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
IV+L +VL S + + L E+C+QDL D+ + VK + Q+LKGL + HS
Sbjct: 63 IVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + +A L +L + +
Sbjct: 121 NVLHRDLKPQNPLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 785 PALDMWAAGCILGD 826
++DMW+AGCI +
Sbjct: 181 TSIDMWSAGCIFAE 194
Score = 61.3 bits (142), Expect = 4e-09
Identities = 28/55 (50%), Positives = 35/55 (63%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK N L+ G +K+ADFGLAR G P R + VVTLWYR P+
Sbjct: 117 CHSRNVLHRDLKPQNPLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
>X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein
kinase protein.
Length = 292
Score = 115 bits (276), Expect = 2e-25
Identities = 68/194 (35%), Positives = 106/194 (54%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL +IGEGTYG V++AKN+ IVALK+VR+D + +G+P S LREI +L +H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
IV+L +VL S + + L E+C+QDL D+ + VK + Q+LKGL + HS
Sbjct: 63 IVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + +A L +L + +
Sbjct: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 785 PALDMWAAGCILGD 826
++DMW+AGCI +
Sbjct: 181 TSIDMWSAGCIFAE 194
Score = 64.1 bits (149), Expect = 6e-10
Identities = 29/55 (52%), Positives = 36/55 (65%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ G +K+ADFGLAR G P R + VVTLWYR P+
Sbjct: 117 CHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
>BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 115 bits (276), Expect = 2e-25
Identities = 68/194 (35%), Positives = 106/194 (54%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL +IGEGTYG V++AKN+ IVALK+VR+D + +G+P S LREI +L +H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
IV+L +VL S + + L E+C+QDL D+ + VK + Q+LKGL + HS
Sbjct: 63 IVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + +A L +L + +
Sbjct: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 785 PALDMWAAGCILGD 826
++DMW+AGCI +
Sbjct: 181 TSIDMWSAGCIFAE 194
Score = 64.1 bits (149), Expect = 6e-10
Identities = 29/55 (52%), Positives = 36/55 (65%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ G +K+ADFGLAR G P R + VVTLWYR P+
Sbjct: 117 CHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
>BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 115 bits (276), Expect = 2e-25
Identities = 68/194 (35%), Positives = 106/194 (54%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL +IGEGTYG V++AKN+ IVALK+VR+D + +G+P S LREI +L +H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
IV+L +VL S + + L E+C+QDL D+ + VK + Q+LKGL + HS
Sbjct: 63 IVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + +A L +L + +
Sbjct: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 785 PALDMWAAGCILGD 826
++DMW+AGCI +
Sbjct: 181 TSIDMWSAGCIFAE 194
Score = 64.1 bits (149), Expect = 6e-10
Identities = 29/55 (52%), Positives = 36/55 (65%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ G +K+ADFGLAR G P R + VVTLWYR P+
Sbjct: 117 CHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
>AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 115 bits (276), Expect = 2e-25
Identities = 68/194 (35%), Positives = 106/194 (54%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL +IGEGTYG V++AKN+ IVALK+VR+D + +G+P S LREI +L +H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
IV+L +VL S + + L E+C+QDL D+ + VK + Q+LKGL + HS
Sbjct: 63 IVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + +A L +L + +
Sbjct: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 785 PALDMWAAGCILGD 826
++DMW+AGCI +
Sbjct: 181 TSIDMWSAGCIFAE 194
Score = 64.1 bits (149), Expect = 6e-10
Identities = 29/55 (52%), Positives = 36/55 (65%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ G +K+ADFGLAR G P R + VVTLWYR P+
Sbjct: 117 CHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 111 bits (267), Expect = 3e-24
Identities = 64/194 (32%), Positives = 105/194 (54%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+AKN+ G +VALKK+R+D+E +G+P + +REI +L +H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM-SSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D+ S +K + Q+L+G+ + HS+
Sbjct: 64 VRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL S T
Sbjct: 122 RVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYT 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSIGCIFAE 195
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/57 (57%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
S C ++HRDLK NLL+ + G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 SFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPE 172
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 111 bits (267), Expect = 3e-24
Identities = 64/194 (32%), Positives = 105/194 (54%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+AKN+ G +VALKK+R+D+E +G+P + +REI +L +H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM-SSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D+ S +K + Q+L+G+ + HS+
Sbjct: 64 VRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL S T
Sbjct: 122 RVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYT 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSIGCIFAE 195
Score = 74.5 bits (175), Expect = 4e-13
Identities = 33/57 (57%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
S C ++HRDLK NLL+ + G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 SFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPE 172
>X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein.
Length = 298
Score = 109 bits (261), Expect = 2e-23
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+A+NK G +VALKK+R+D E +G+P + +REI +L H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL S +
Sbjct: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGSKYYS 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSLGCIFAE 195
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
>M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kinase
protein.
Length = 298
Score = 107 bits (256), Expect = 6e-23
Identities = 62/194 (31%), Positives = 102/194 (52%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+A+NK G +VALKK+R+D E +G+P + +REI +L H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL +
Sbjct: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSLGCIFAE 195
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
>BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 107 bits (256), Expect = 6e-23
Identities = 62/194 (31%), Positives = 102/194 (52%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+A+NK G +VALKK+R+D E +G+P + +REI +L H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL +
Sbjct: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSLGCIFAE 195
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
>BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 107 bits (256), Expect = 6e-23
Identities = 62/194 (31%), Positives = 102/194 (52%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+A+NK G +VALKK+R+D E +G+P + +REI +L H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL +
Sbjct: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSLGCIFAE 195
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
>AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 107 bits (256), Expect = 6e-23
Identities = 62/194 (31%), Positives = 102/194 (52%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+A+NK G +VALKK+R+D E +G+P + +REI +L H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL +
Sbjct: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSLGCIFAE 195
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
>X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein.
Length = 298
Score = 105 bits (253), Expect = 1e-22
Identities = 62/194 (31%), Positives = 101/194 (52%), Gaps = 1/194 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IGEGTYG+VY+A+NK G +VALKK+R D E +G+P + +REI +L H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRXDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + L ILL +
Sbjct: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 785 PALDMWAAGCILGD 826
A+D+W+ GCI +
Sbjct: 182 TAVDIWSLGCIFAE 195
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T VVTLWYRAPE
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
>Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycle
control gene CDC2. ).
Length = 297
Score = 101 bits (243), Expect = 2e-21
Identities = 47/121 (38%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM--SSPFTESQVKCLMLQVLKGLKYLH 598
IV L++VL+ S ++L E+ DL LD++ S VK + Q+L+G+ + H
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 599 S 601
S
Sbjct: 121 S 121
Score = 73.3 bits (172), Expect = 1e-12
Identities = 33/55 (60%), Positives = 39/55 (70%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ DKG +K+ADFGLAR G P R T VVTLWYR+PE
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 173
>X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene
involved in cell cycle control. ).
Length = 297
Score = 101 bits (243), Expect = 2e-21
Identities = 47/121 (38%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM--SSPFTESQVKCLMLQVLKGLKYLH 598
IV L++VL+ S ++L E+ DL LD++ S VK + Q+L+G+ + H
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 599 S 601
S
Sbjct: 121 S 121
Score = 73.3 bits (172), Expect = 1e-12
Identities = 33/55 (60%), Positives = 39/55 (70%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ DKG +K+ADFGLAR G P R T VVTLWYR+PE
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 173
>BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 101 bits (243), Expect = 2e-21
Identities = 47/121 (38%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM--SSPFTESQVKCLMLQVLKGLKYLH 598
IV L++VL+ S ++L E+ DL LD++ S VK + Q+L+G+ + H
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 599 S 601
S
Sbjct: 121 S 121
Score = 73.3 bits (172), Expect = 1e-12
Identities = 33/55 (60%), Positives = 39/55 (70%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ DKG +K+ADFGLAR G P R T VVTLWYR+PE
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 173
>BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein.
Length = 225
Score = 101 bits (243), Expect = 2e-21
Identities = 47/121 (38%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM--SSPFTESQVKCLMLQVLKGLKYLH 598
IV L++VL+ S ++L E+ DL LD++ S VK + Q+L+G+ + H
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 599 S 601
S
Sbjct: 121 S 121
Score = 73.3 bits (172), Expect = 1e-12
Identities = 33/55 (60%), Positives = 39/55 (70%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ DKG +K+ADFGLAR G P R T VVTLWYR+PE
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 173
>BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 101 bits (243), Expect = 2e-21
Identities = 47/121 (38%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM--SSPFTESQVKCLMLQVLKGLKYLH 598
IV L++VL+ S ++L E+ DL LD++ S VK + Q+L+G+ + H
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 599 S 601
S
Sbjct: 121 S 121
Score = 73.3 bits (172), Expect = 1e-12
Identities = 33/55 (60%), Positives = 39/55 (70%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ DKG +K+ADFGLAR G P R T VVTLWYR+PE
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 173
>AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 101 bits (243), Expect = 2e-21
Identities = 47/121 (38%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM--SSPFTESQVKCLMLQVLKGLKYLH 598
IV L++VL+ S ++L E+ DL LD++ S VK + Q+L+G+ + H
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 599 S 601
S
Sbjct: 121 S 121
Score = 73.3 bits (172), Expect = 1e-12
Identities = 33/55 (60%), Positives = 39/55 (70%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C ++HRDLK NLL+ DKG +K+ADFGLAR G P R T VVTLWYR+PE
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 173
>AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein.
Length = 264
Score = 101 bits (241), Expect = 4e-21
Identities = 47/120 (39%), Positives = 79/120 (65%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+K+ +IG+GTYG+VY+A+NK+ G +VALKK+R+D E +G+P + +REI +L H NI
Sbjct: 4 FQKVAQIGQGTYGVVYKARNKSTGQMVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLD-NMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L +V+ + ++L E+ QDL +D + + +K + Q+L+GL + HS+
Sbjct: 64 VKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
Score = 52.0 bits (119), Expect = 3e-06
Identities = 23/48 (47%), Positives = 31/48 (64%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRV 731
+ C ++HRDLK NLL+ +G +K+ADFGLAR G P R+ T V
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV 163
>AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein.
Length = 453
Score = 100 bits (239), Expect = 7e-21
Identities = 58/190 (30%), Positives = 93/190 (48%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+EKL ++GEG+Y VY+ K+K NG +VALK +R+ E++G P + +RE +L +H NI
Sbjct: 119 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHANI 177
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNF 607
V L +++ + E++ L EY DL +D VK + Q+L+GL Y+H +
Sbjct: 178 VLLHDII--HTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRY 235
Query: 608 HCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTP 787
L+ + + + F + P + L +LL S +
Sbjct: 236 ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYST 295
Query: 788 ALDMWAAGCI 817
LDMW GCI
Sbjct: 296 CLDMWGVGCI 305
Score = 64.5 bits (150), Expect = 4e-10
Identities = 28/51 (54%), Positives = 38/51 (74%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK NLL++D G +K+ADFGLAR P+ + + VVTLWYR P+
Sbjct: 235 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPD 285
>AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protein
kinase PFTAIRE-1 protein.
Length = 469
Score = 97.1 bits (231), Expect = 7e-20
Identities = 57/190 (30%), Positives = 92/190 (48%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+EKL ++GEG+Y VY+ K+K N +VALK +R+ E++G P + +RE +L +H NI
Sbjct: 135 YEKLEKLGEGSYATVYKGKSKVNWKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHANI 193
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNF 607
V L +++ + E++ L EY DL +D VK + Q+L+GL Y+H +
Sbjct: 194 VLLHDII--HTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRY 251
Query: 608 HCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTP 787
L+ + + + F + P + L +LL S +
Sbjct: 252 ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYST 311
Query: 788 ALDMWAAGCI 817
LDMW GCI
Sbjct: 312 CLDMWGVGCI 321
Score = 64.5 bits (150), Expect = 4e-10
Identities = 28/51 (54%), Positives = 38/51 (74%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK NLL++D G +K+ADFGLAR P+ + + VVTLWYR P+
Sbjct: 251 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPD 301
>DQ411039-1|ABD66016.1| 260|Homo sapiens protein kinase CDK5
splicing variant protein.
Length = 260
Score = 95.1 bits (226), Expect = 3e-19
Identities = 47/104 (45%), Positives = 69/104 (66%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL +IGEGTYG V++AKN+ IVALK+VR+D + +G+P S LREI +L +H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVK 556
IV+L +VL S + + L E+C+QDL D+ + VK
Sbjct: 63 IVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVK 104
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/38 (52%), Positives = 25/38 (65%)
Frame = +3
Query: 645 LTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+ G +K+ADFGLAR G P R + VVTLWYR P+
Sbjct: 102 IVKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 139
>X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein
kinase protein.
Length = 496
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 167 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 225
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 226 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 283
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 284 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 343
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 344 DMWGVGCI 351
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 282 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
>BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 167 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 225
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 226 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 283
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 284 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 343
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 344 DMWGVGCI 351
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 282 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
>BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 167 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 225
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 226 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 283
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 284 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 343
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 344 DMWGVGCI 351
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 282 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
>BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein.
Length = 395
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 66 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 124
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 125 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 182
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 183 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 242
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 243 DMWGVGCI 250
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 181 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 237
>BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein.
Length = 448
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 119 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 177
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 178 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 235
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 236 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 295
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 296 DMWGVGCI 303
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 234 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 290
>BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 167 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 225
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 226 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 283
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 284 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 343
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 344 DMWGVGCI 351
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 282 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
>AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 93.9 bits (223), Expect = 6e-19
Identities = 58/188 (30%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 167 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 225
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL LD+ + VK + Q+L+GL Y H
Sbjct: 226 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVL 283
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L ILL S + +
Sbjct: 284 HRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQI 343
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 344 DMWGVGCI 351
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
++HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+ D
Sbjct: 282 VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
>AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase 3
isoform b protein.
Length = 504
Score = 92.3 bits (219), Expect = 2e-18
Identities = 58/191 (30%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 174 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 232
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 233 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 289
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 290 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 349
Query: 785 PALDMWAAGCI 817
+DMW GCI
Sbjct: 350 TPIDMWGVGCI 360
Score = 62.9 bits (146), Expect = 1e-09
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 291 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 340
>AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase 3
isoform a protein.
Length = 474
Score = 92.3 bits (219), Expect = 2e-18
Identities = 58/191 (30%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 144 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 202
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 203 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 259
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 260 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 319
Query: 785 PALDMWAAGCI 817
+DMW GCI
Sbjct: 320 TPIDMWGVGCI 330
Score = 62.9 bits (146), Expect = 1e-09
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 261 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 310
>AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 92.3 bits (219), Expect = 2e-18
Identities = 58/191 (30%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 200
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 201 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 785 PALDMWAAGCI 817
+DMW GCI
Sbjct: 318 TPIDMWGVGCI 328
Score = 62.9 bits (146), Expect = 1e-09
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 259 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 308
>AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase 3
isoform b variant protein.
Length = 436
Score = 92.3 bits (219), Expect = 2e-18
Identities = 58/191 (30%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 106 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 164
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 165 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 221
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 222 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 281
Query: 785 PALDMWAAGCI 817
+DMW GCI
Sbjct: 282 TPIDMWGVGCI 292
Score = 62.9 bits (146), Expect = 1e-09
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 223 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 272
>D88357-1|BAA26001.1| 240|Homo sapiens CDC2 delta T protein.
Length = 240
Score = 91.5 bits (217), Expect = 3e-18
Identities = 39/94 (41%), Positives = 66/94 (70%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++ K+ +IGEGTYG+VY+ ++K G +VA+KK+R++ E++G+P + +REI +L RH N
Sbjct: 3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNM 526
IV L++VL+ S ++L E+ DL LD++
Sbjct: 63 IVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSI 94
>BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein
kinase 3 protein.
Length = 472
Score = 91.5 bits (217), Expect = 3e-18
Identities = 58/191 (30%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 200
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 201 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 785 PALDMWAAGCI 817
+DMW GCI
Sbjct: 318 TPIDMWGVGCI 328
Score = 62.9 bits (146), Expect = 1e-09
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 259 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 308
>BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase 2
protein.
Length = 523
Score = 91.5 bits (217), Expect = 3e-18
Identities = 55/188 (29%), Positives = 96/188 (51%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL ++GEGTY VY+ ++K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 194 KLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 252
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL +D+ + + VK + Q+L+GL Y H
Sbjct: 253 LHDIV--HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVL 310
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L +LL S + +
Sbjct: 311 HRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQI 370
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 371 DMWGVGCI 378
Score = 63.7 bits (148), Expect = 8e-10
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
++HRDLK NLL+ +KG +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 309 VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 358
>BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 91.5 bits (217), Expect = 3e-18
Identities = 58/191 (30%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 200
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 201 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 785 PALDMWAAGCI 817
+DMW GCI
Sbjct: 318 TPIDMWGVGCI 328
Score = 62.9 bits (146), Expect = 1e-09
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 259 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 308
>X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein
kinase protein.
Length = 523
Score = 90.6 bits (215), Expect = 6e-18
Identities = 55/188 (29%), Positives = 95/188 (50%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL ++GEGTY VY+ ++K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 194 KLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 252
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
L +++ + +S+ L EY ++DL +D+ + + VK + Q+L+GL Y H
Sbjct: 253 LHDIV--HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVL 310
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTPAL 793
L+ N + + F + P + + L +LL S +
Sbjct: 311 HRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYLTQI 370
Query: 794 DMWAAGCI 817
DMW GCI
Sbjct: 371 DMWGVGCI 378
Score = 63.7 bits (148), Expect = 8e-10
Identities = 27/50 (54%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
++HRDLK NLL+ +KG +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 309 VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 358
>X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein
kinase protein.
Length = 326
Score = 90.2 bits (214), Expect = 8e-18
Identities = 55/140 (39%), Positives = 88/140 (62%), Gaps = 8/140 (5%)
Frame = +2
Query: 209 EKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGS-IVALKKVRMDVEKDGLPLSGL 385
EKD G CR ++E + IGEG YG V++A++ NG VALK+VR+ ++G+PLS +
Sbjct: 2 EKD--GLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTI 59
Query: 386 REIQVLM---SCRHENIVQLKEV-LVGRSLESIFLSM--EYCEQDLASLLDNMSSPFTES 547
RE+ VL + H N+V+L +V V R+ L++ E+ +QDL + LD + P +
Sbjct: 60 REVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPT 119
Query: 548 Q-VKCLMLQVLKGLKYLHSN 604
+ +K +M Q+L+GL +LHS+
Sbjct: 120 ETIKDMMFQLLRGLDFLHSH 139
Score = 60.1 bits (139), Expect = 1e-08
Identities = 29/50 (58%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+VHRDLK N+L+T G +K+ADFGLAR + + + T VVTLWYRAPE
Sbjct: 141 VVHRDLKPQNILVTSSGQIKLADFGLAR-IYSFQMALTSVVVTLWYRAPE 189
>BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 90.2 bits (214), Expect = 8e-18
Identities = 55/140 (39%), Positives = 88/140 (62%), Gaps = 8/140 (5%)
Frame = +2
Query: 209 EKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGS-IVALKKVRMDVEKDGLPLSGL 385
EKD G CR ++E + IGEG YG V++A++ NG VALK+VR+ ++G+PLS +
Sbjct: 2 EKD--GLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTI 59
Query: 386 REIQVLM---SCRHENIVQLKEV-LVGRSLESIFLSM--EYCEQDLASLLDNMSSPFTES 547
RE+ VL + H N+V+L +V V R+ L++ E+ +QDL + LD + P +
Sbjct: 60 REVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPT 119
Query: 548 Q-VKCLMLQVLKGLKYLHSN 604
+ +K +M Q+L+GL +LHS+
Sbjct: 120 ETIKDMMFQLLRGLDFLHSH 139
Score = 60.1 bits (139), Expect = 1e-08
Identities = 29/50 (58%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+VHRDLK N+L+T G +K+ADFGLAR + + + T VVTLWYRAPE
Sbjct: 141 VVHRDLKPQNILVTSSGQIKLADFGLAR-IYSFQMALTSVVVTLWYRAPE 189
>AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 90.2 bits (214), Expect = 8e-18
Identities = 55/140 (39%), Positives = 88/140 (62%), Gaps = 8/140 (5%)
Frame = +2
Query: 209 EKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGS-IVALKKVRMDVEKDGLPLSGL 385
EKD G CR ++E + IGEG YG V++A++ NG VALK+VR+ ++G+PLS +
Sbjct: 2 EKD--GLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTI 59
Query: 386 REIQVLM---SCRHENIVQLKEV-LVGRSLESIFLSM--EYCEQDLASLLDNMSSPFTES 547
RE+ VL + H N+V+L +V V R+ L++ E+ +QDL + LD + P +
Sbjct: 60 REVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPT 119
Query: 548 Q-VKCLMLQVLKGLKYLHSN 604
+ +K +M Q+L+GL +LHS+
Sbjct: 120 ETIKDMMFQLLRGLDFLHSH 139
Score = 60.1 bits (139), Expect = 1e-08
Identities = 29/50 (58%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+VHRDLK N+L+T G +K+ADFGLAR + + + T VVTLWYRAPE
Sbjct: 141 VVHRDLKPQNILVTSSGQIKLADFGLAR-IYSFQMALTSVVVTLWYRAPE 189
>X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein
kinase protein.
Length = 380
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/191 (29%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 50 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 108
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H+
Sbjct: 109 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHTR 165
Query: 605 FHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQT 784
L+ N + + F + P + + L +LL S +
Sbjct: 166 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 225
Query: 785 PALDMWAAGCI 817
+ MW GCI
Sbjct: 226 TPIAMWGVGCI 236
Score = 63.3 bits (147), Expect = 1e-09
Identities = 28/55 (50%), Positives = 38/55 (69%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
C I+HRDLK NLL+ ++G +K+ADFGLAR P ++ + VVTLWYR P+
Sbjct: 162 CHTRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 216
>AL357131-3|CAH72011.1| 280|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 280
Score = 89.0 bits (211), Expect = 2e-17
Identities = 44/118 (37%), Positives = 75/118 (63%), Gaps = 1/118 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 200
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL Y H
Sbjct: 201 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 255
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/22 (54%), Positives = 18/22 (81%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIA 674
I+HRDLK NLL+ ++G +K+A
Sbjct: 259 ILHRDLKPQNLLINERGELKLA 280
>Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein
kinase protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinase
(CAK) protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase
protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase
protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine
kinase protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase 7
protein.
Length = 346
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>AC072061-2|AAS07490.1| 170|Homo sapiens unknown protein.
Length = 170
Score = 88.2 bits (209), Expect = 3e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI R V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 75 ETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 134
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR 457
+REI++L H++I+ +KE++ +
Sbjct: 135 AIREIKILRQLTHQSIINMKEIVTDK 160
>AC072061-1|AAS07491.1| 784|Homo sapiens unknown protein.
Length = 784
Score = 88.2 bits (209), Expect = 3e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +2
Query: 200 EIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS 379
E EKDI R V +F+ + IGEGTYG VY+A++K G +VALKKVR+D EK+G P++
Sbjct: 689 ETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPIT 748
Query: 380 GLREIQVLMSCRHENIVQLKEVLVGR 457
+REI++L H++I+ +KE++ +
Sbjct: 749 AIREIKILRQLTHQSIINMKEIVTDK 774
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 87.8 bits (208), Expect = 4e-17
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 3/196 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLMSCRH 418
+EKL+ +GEG + VY+A++K IVA+KK+++ KDG+ + LREI++L H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
NI+ L + +S +I L ++ E DL ++ + S T S +K ML L+GL+YLH
Sbjct: 72 PNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
++ L+ + + + + F + P + +L +
Sbjct: 130 RHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 779 QTPALDMWAAGCILGD 826
+DMWA GCIL +
Sbjct: 190 YGVGVDMWAVGCILAE 205
Score = 70.1 bits (164), Expect = 9e-12
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+I+HRDLK +NLLL + G +K+ADFGLA+ G+P R+ T +VVT WYRAPE
Sbjct: 132 WILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPE 182
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 87.4 bits (207), Expect = 6e-17
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 5/201 (2%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ +FE L +GEG YG+V + ++K IVA+KK + E + + + LRE+++L + +
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
ENIV+LKE R ++L EY E+++ LL+ M + +VK + Q++K + + H
Sbjct: 70 ENIVELKEAF--RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCH 127
Query: 599 SN--FHCA*GLEGVQSSFN-**RLCQNS*FRSSSLVRRPGQKCNAS--CCHLMV*GARIL 763
N H E + S N +LC R+ S G N + +L
Sbjct: 128 KNDIVHRDIKPENLLISHNDVLKLCDFGFARNLS----EGNNANYTEYVATRWYRSPELL 183
Query: 764 LQSPRQTPALDMWAAGCILGD 826
L +P ++DMW+ GCILG+
Sbjct: 184 LGAP-YGKSVDMWSVGCILGE 203
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLG-APARSATPRVVTLWYRAPE 758
C IVHRD+K NLL++ +K+ DFG AR L + T V T WYR+PE
Sbjct: 126 CHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPE 181
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 87.4 bits (207), Expect = 6e-17
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 5/201 (2%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ +FE L +GEG YG+V + ++K IVA+KK + E + + + LRE+++L + +
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
ENIV+LKE R ++L EY E+++ LL+ M + +VK + Q++K + + H
Sbjct: 70 ENIVELKEAF--RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCH 127
Query: 599 SN--FHCA*GLEGVQSSFN-**RLCQNS*FRSSSLVRRPGQKCNAS--CCHLMV*GARIL 763
N H E + S N +LC R+ S G N + +L
Sbjct: 128 KNDIVHRDIKPENLLISHNDVLKLCDFGFARNLS----EGNNANYTEYVATRWYRSPELL 183
Query: 764 LQSPRQTPALDMWAAGCILGD 826
L +P ++DMW+ GCILG+
Sbjct: 184 LGAP-YGKSVDMWSVGCILGE 203
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLG-APARSATPRVVTLWYRAPE 758
C IVHRD+K NLL++ +K+ DFG AR L + T V T WYR+PE
Sbjct: 126 CHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPE 181
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 87.4 bits (207), Expect = 6e-17
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 5/201 (2%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ +FE L +GEG YG+V + ++K IVA+KK + E + + + LRE+++L + +
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
ENIV+LKE R ++L EY E+++ LL+ M + +VK + Q++K + + H
Sbjct: 70 ENIVELKEAF--RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCH 127
Query: 599 SN--FHCA*GLEGVQSSFN-**RLCQNS*FRSSSLVRRPGQKCNAS--CCHLMV*GARIL 763
N H E + S N +LC R+ S G N + +L
Sbjct: 128 KNDIVHRDIKPENLLISHNDVLKLCDFGFARNLS----EGNNANYTEYVATRWYRSPELL 183
Query: 764 LQSPRQTPALDMWAAGCILGD 826
L +P ++DMW+ GCILG+
Sbjct: 184 LGAP-YGKSVDMWSVGCILGE 203
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLG-APARSATPRVVTLWYRAPE 758
C IVHRD+K NLL++ +K+ DFG AR L + T V T WYR+PE
Sbjct: 126 CHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPE 181
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 87.4 bits (207), Expect = 6e-17
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 5/201 (2%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ +FE L +GEG YG+V + ++K IVA+KK + E + + + LRE+++L + +
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
ENIV+LKE R ++L EY E+++ LL+ M + +VK + Q++K + + H
Sbjct: 70 ENIVELKEAF--RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCH 127
Query: 599 SN--FHCA*GLEGVQSSFN-**RLCQNS*FRSSSLVRRPGQKCNAS--CCHLMV*GARIL 763
N H E + S N +LC R+ S G N + +L
Sbjct: 128 KNDIVHRDIKPENLLISHNDVLKLCDFGFARNLS----EGNNANYTEYVATRWYRSPELL 183
Query: 764 LQSPRQTPALDMWAAGCILGD 826
L +P ++DMW+ GCILG+
Sbjct: 184 LGAP-YGKSVDMWSVGCILGE 203
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Frame = +3
Query: 594 CIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLG-APARSATPRVVTLWYRAPE 758
C IVHRD+K NLL++ +K+ DFG AR L + T V T WYR+PE
Sbjct: 126 CHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPE 181
>AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 85.4 bits (202), Expect = 2e-16
Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G IVALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIV 124
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQ-TPA 790
L+ + + + F + + G + A LL RQ
Sbjct: 125 HRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQG 184
Query: 791 LDMWAAGCILGD 826
+D+W+ GCI+G+
Sbjct: 185 VDLWSVGCIMGE 196
Score = 59.3 bits (137), Expect = 2e-08
Identities = 31/58 (53%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAP-ARSATPRVVTLWYRAPE 758
+ C IVHRDLK +NLL++ G +KIADFGLAR +R T +V T WYRAPE
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPE 173
>AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 85.4 bits (202), Expect = 2e-16
Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G IVALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHC 613
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIV 124
Query: 614 A*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQ-TPA 790
L+ + + + F + + G + A LL RQ
Sbjct: 125 HRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQG 184
Query: 791 LDMWAAGCILGD 826
+D+W+ GCI+G+
Sbjct: 185 VDLWSVGCIMGE 196
Score = 59.3 bits (137), Expect = 2e-08
Identities = 31/58 (53%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLARWLGAP-ARSATPRVVTLWYRAPE 758
+ C IVHRDLK +NLL++ G +KIADFGLAR +R T +V T WYRAPE
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPE 173
>BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein.
Length = 349
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/190 (29%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L ++GEG+Y VY+ ++ NG +VALK + M+ E +G+P + +RE +L +H NIV L
Sbjct: 55 LEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANIVLL 113
Query: 437 KEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA 616
+++ + E++ EY DLA + V+ M Q+L+GL Y+H
Sbjct: 114 HDII--HTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLH 171
Query: 617 *GLEG---VQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTP 787
L+ + S +L R+ S+ P Q ++ L LL + +
Sbjct: 172 RDLKPQNLLISHLGELKLADFGLARAKSI---PSQTYSSEVVTLWYRPPDALLGATEYSS 228
Query: 788 ALDMWAAGCI 817
LD+W AGCI
Sbjct: 229 ELDIWGAGCI 238
Score = 60.1 bits (139), Expect = 1e-08
Identities = 26/50 (52%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
++HRDLK NLL++ G +K+ADFGLAR P+++ + VVTLWYR P+
Sbjct: 169 VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPD 218
>AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein.
Length = 301
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/190 (29%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L ++GEG+Y VY+ ++ NG +VALK + M+ E +G+P + +RE +L +H NIV L
Sbjct: 55 LEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANIVLL 113
Query: 437 KEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA 616
+++ + E++ EY DLA + V+ M Q+L+GL Y+H
Sbjct: 114 HDII--HTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLH 171
Query: 617 *GLEG---VQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTP 787
L+ + S +L R+ S+ P Q ++ L LL + +
Sbjct: 172 RDLKPQNLLISHLGELKLADFGLARAKSI---PSQTYSSEVVTLWYRPPDALLGATEYSS 228
Query: 788 ALDMWAAGCI 817
LD+W AGCI
Sbjct: 229 ELDIWGAGCI 238
Score = 60.1 bits (139), Expect = 1e-08
Identities = 26/50 (52%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
++HRDLK NLL++ G +K+ADFGLAR P+++ + VVTLWYR P+
Sbjct: 169 VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPD 218
>AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein.
Length = 384
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/190 (29%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L ++GEG+Y VY+ ++ NG +VALK + M+ E +G+P + +RE +L +H NIV L
Sbjct: 55 LEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANIVLL 113
Query: 437 KEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSNFHCA 616
+++ + E++ EY DLA + V+ M Q+L+GL Y+H
Sbjct: 114 HDII--HTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLH 171
Query: 617 *GLEG---VQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPRQTP 787
L+ + S +L R+ S+ P Q ++ L LL + +
Sbjct: 172 RDLKPQNLLISHLGELKLADFGLARAKSI---PSQTYSSEVVTLWYRPPDALLGATEYSS 228
Query: 788 ALDMWAAGCI 817
LD+W AGCI
Sbjct: 229 ELDIWGAGCI 238
Score = 60.1 bits (139), Expect = 1e-08
Identities = 26/50 (52%), Positives = 37/50 (74%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
++HRDLK NLL++ G +K+ADFGLAR P+++ + VVTLWYR P+
Sbjct: 169 VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPD 218
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/197 (27%), Positives = 92/197 (46%), Gaps = 3/197 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EK+ +IGEG+YG+V++ +N+ G IVA+KK + + LREI++L +H N
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+V L EV R + L EYC+ + LD E VK + Q L+ + + H +
Sbjct: 64 LVNLLEVF--RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
Query: 605 --FHCA*GLEGVQ-SSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H E + + + +LC F + L+ P +L+
Sbjct: 122 NCIHRDVKPENILITKHSVIKLCD---FGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 776 RQTPALDMWAAGCILGD 826
+ P +D+WA GC+ +
Sbjct: 179 QYGPPVDVWAIGCVFAE 195
Score = 54.8 bits (126), Expect = 4e-07
Identities = 23/49 (46%), Positives = 31/49 (63%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+L+T +K+ DFG AR L P+ T V T WYR+PE
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPE 172
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/197 (27%), Positives = 92/197 (46%), Gaps = 3/197 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EK+ +IGEG+YG+V++ +N+ G IVA+KK + + LREI++L +H N
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+V L EV R + L EYC+ + LD E VK + Q L+ + + H +
Sbjct: 64 LVNLLEVF--RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
Query: 605 --FHCA*GLEGVQ-SSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H E + + + +LC F + L+ P +L+
Sbjct: 122 NCIHRDVKPENILITKHSVIKLCD---FGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 776 RQTPALDMWAAGCILGD 826
+ P +D+WA GC+ +
Sbjct: 179 QYGPPVDVWAIGCVFAE 195
Score = 54.8 bits (126), Expect = 4e-07
Identities = 23/49 (46%), Positives = 31/49 (63%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+L+T +K+ DFG AR L P+ T V T WYR+PE
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPE 172
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/197 (27%), Positives = 92/197 (46%), Gaps = 3/197 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EK+ +IGEG+YG+V++ +N+ G IVA+KK + + LREI++L +H N
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+V L EV R + L EYC+ + LD E VK + Q L+ + + H +
Sbjct: 64 LVNLLEVF--RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
Query: 605 --FHCA*GLEGVQ-SSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H E + + + +LC F + L+ P +L+
Sbjct: 122 NCIHRDVKPENILITKHSVIKLCD---FGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 776 RQTPALDMWAAGCILGD 826
+ P +D+WA GC+ +
Sbjct: 179 QYGPPVDVWAIGCVFAE 195
Score = 54.8 bits (126), Expect = 4e-07
Identities = 23/49 (46%), Positives = 31/49 (63%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+L+T +K+ DFG AR L P+ T V T WYR+PE
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPE 172
>AL357131-2|CAH72010.1| 282|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 282
Score = 83.8 bits (198), Expect = 7e-16
Identities = 42/114 (36%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ KL+++GEGTY V++ ++K ++VALK++R++ E +G P + +RE+ +L + +H NI
Sbjct: 172 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI 230
Query: 428 VQLKEVL-VGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGL 586
V L +++ RSL +F EY + DL LD+ + + VK M Q+L+GL
Sbjct: 231 VTLHDLIHTDRSLTLVF---EYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGL 281
>BC002655-1|AAH02655.1| 275|Homo sapiens CCRK protein protein.
Length = 275
Score = 83.4 bits (197), Expect = 9e-16
Identities = 46/117 (39%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G IVALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Score = 44.8 bits (101), Expect = 4e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR 692
+ C IVHRDLK +NLL++ G +KIADFGLAR
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLAR 150
>AY904367-1|AAW82349.1| 243|Homo sapiens cell cycle-related kinase
cardiac splice variant protein.
Length = 243
Score = 83.4 bits (197), Expect = 9e-16
Identities = 46/117 (39%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G IVALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Score = 44.8 bits (101), Expect = 4e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR 692
+ C IVHRDLK +NLL++ G +KIADFGLAR
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLAR 150
>AL353572-5|CAH72843.1| 325|Homo sapiens cell cycle related kinase
protein.
Length = 325
Score = 83.4 bits (197), Expect = 9e-16
Identities = 46/117 (39%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G IVALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Score = 44.8 bits (101), Expect = 4e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR 692
+ C IVHRDLK +NLL++ G +KIADFGLAR
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLAR 150
>AF113130-1|AAF43778.1| 452|Homo sapiens cyclin-dependent protein
kinase H protein.
Length = 452
Score = 83.0 bits (196), Expect = 1e-15
Identities = 45/117 (38%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G I+ALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Score = 44.8 bits (101), Expect = 4e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR 692
+ C IVHRDLK +NLL++ G +KIADFGLAR
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLAR 150
>AF035013-1|AAC98920.1| 452|Homo sapiens cell cycle related kinase
protein.
Length = 452
Score = 83.0 bits (196), Expect = 1e-15
Identities = 45/117 (38%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCR-HENIVQ 433
L RIGEG +GIV++AK+ G I+ALKKV + +DG P LREI+ L ++ +VQ
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
LK V L+ E+ DLA ++ + P ++QVK + +LKG+ + H+N
Sbjct: 67 LKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Score = 44.8 bits (101), Expect = 4e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR 692
+ C IVHRDLK +NLL++ G +KIADFGLAR
Sbjct: 116 AFCHANNIVHRDLKPANLLISASGQLKIADFGLAR 150
>U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor
kinase protein.
Length = 833
Score = 80.6 bits (190), Expect = 6e-15
Identities = 45/135 (33%), Positives = 78/135 (57%)
Frame = +2
Query: 197 MEIPEKDILGKCRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPL 376
M++ + DI + ++ L R+G GTYG V++A++K +G +VALK V+M+ + D L
Sbjct: 1 MDVVDPDIFNRDPR-DHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTL 59
Query: 377 SGLREIQVLMSCRHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVK 556
+EI +L +CRH NIV + L+ +++ ME+C + ++ +E Q+
Sbjct: 60 Q--KEILILKTCRHANIVAYHGSYLW--LQKLWICMEFCGAGSLQDIYQVTGSLSELQIS 115
Query: 557 CLMLQVLKGLKYLHS 601
+ +VL+GL YLHS
Sbjct: 116 YVCREVLQGLAYLHS 130
Score = 44.8 bits (101), Expect = 4e-04
Identities = 19/49 (38%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+L+ D G V++ADFG++ +GA + T ++ APE
Sbjct: 134 IHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPE 182
>AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 379
Score = 79.4 bits (187), Expect = 1e-14
Identities = 39/118 (33%), Positives = 67/118 (56%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL + GEG+YG+V++ +NK +G +VA+KK + + LREI++L +H N
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+V L EV R + L EYC+ L + L+ + + +K ++ Q L+ L + H
Sbjct: 63 LVNLIEVF--RRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCH 118
Score = 55.2 bits (127), Expect = 3e-07
Identities = 25/49 (51%), Positives = 33/49 (67%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+L+T +G +KI DFG A+ L P + T V T WYRAPE
Sbjct: 123 IHRDIKPENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPE 170
>AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 315
Score = 79.4 bits (187), Expect = 1e-14
Identities = 39/118 (33%), Positives = 67/118 (56%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++EKL + GEG+YG+V++ +NK +G +VA+KK + + LREI++L +H N
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+V L EV R + L EYC+ L + L+ + + +K ++ Q L+ L + H
Sbjct: 63 LVNLIEVF--RRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCH 118
Score = 55.2 bits (127), Expect = 3e-07
Identities = 25/49 (51%), Positives = 33/49 (67%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+L+T +G +KI DFG A+ L P + T V T WYRAPE
Sbjct: 123 IHRDIKPENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPE 170
>BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein.
Length = 292
Score = 76.6 bits (180), Expect = 1e-13
Identities = 50/197 (25%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V ++ +G ++A+KK++ LRE++ L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNLREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+V+LKEV+ R + ++ EY +++L L+ + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSP 775
+ L+ L + + F + +R +P S +LL+S
Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYR--APEVLLRST 175
Query: 776 RQTPALDMWAAGCILGD 826
+ +D+WA GCI+ +
Sbjct: 176 NYSSPIDVWAVGCIMAE 192
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRDLK NLL VKIADFGLAR + + T V T WYRAPE
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPE 169
>AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 76.6 bits (180), Expect = 1e-13
Identities = 50/197 (25%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V ++ +G ++A+KK++ LRE++ L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNLREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+V+LKEV+ R + ++ EY +++L L+ + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSP 775
+ L+ L + + F + +R +P S +LL+S
Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYR--APEVLLRST 175
Query: 776 RQTPALDMWAAGCILGD 826
+ +D+WA GCI+ +
Sbjct: 176 NYSSPIDVWAVGCIMAE 192
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRDLK NLL VKIADFGLAR + + T V T WYRAPE
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPE 169
>AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 76.6 bits (180), Expect = 1e-13
Identities = 50/197 (25%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V ++ +G ++A+KK++ LRE++ L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNLREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+V+LKEV+ R + ++ EY +++L L+ + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSP 775
+ L+ L + + F + +R +P S +LL+S
Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYR--APEVLLRST 175
Query: 776 RQTPALDMWAAGCILGD 826
+ +D+WA GCI+ +
Sbjct: 176 NYSSPIDVWAVGCIMAE 192
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRDLK NLL VKIADFGLAR + + T V T WYRAPE
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPE 169
>AK131486-1|BAD18631.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ16665 fis, clone THYMU2031249, highly similar
to SERINE/THREONINE-PROTEIN KINASE PCTAIRE-1 (EC
2.7.1.-). ).
Length = 356
Score = 76.6 bits (180), Expect = 1e-13
Identities = 37/101 (36%), Positives = 64/101 (63%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 188 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 246
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVK 556
L +++ + +S+ L EY ++DL LD+ + VK
Sbjct: 247 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVK 285
>AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase
protein.
Length = 632
Score = 76.6 bits (180), Expect = 1e-13
Identities = 50/197 (25%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V ++ +G ++A+KK++ LRE++ L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNLREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+V+LKEV+ R + ++ EY +++L L+ + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSP 775
+ L+ L + + F + +R +P S +LL+S
Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYR--APEVLLRST 175
Query: 776 RQTPALDMWAAGCILGD 826
+ +D+WA GCI+ +
Sbjct: 176 NYSSPIDVWAVGCIMAE 192
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRDLK NLL VKIADFGLAR + + T V T WYRAPE
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPE 169
>AB209465-1|BAD92702.1| 556|Homo sapiens Hypothetical protein
FLJ16665 variant protein.
Length = 556
Score = 76.6 bits (180), Expect = 1e-13
Identities = 37/101 (36%), Positives = 64/101 (63%)
Frame = +2
Query: 254 KLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQ 433
KL+++GEGTY VY+ K+K ++VALK++R++ E +G P + +RE+ +L +H NIV
Sbjct: 195 KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVT 253
Query: 434 LKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVK 556
L +++ + +S+ L EY ++DL LD+ + VK
Sbjct: 254 LHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVK 292
Score = 31.9 bits (69), Expect = 2.9
Identities = 14/33 (42%), Positives = 18/33 (54%)
Frame = +3
Query: 681 GLARWLGAPARSATPRVVTLWYRAPEYFCSHHD 779
GLAR P ++ + VVTLWYR P+ D
Sbjct: 366 GLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 398
>AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein.
Length = 640
Score = 76.6 bits (180), Expect = 1e-13
Identities = 50/197 (25%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V ++ +G ++A+KK++ LRE++ L H
Sbjct: 9 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNLREVKSLKKLNH 67
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+V+LKEV+ R + ++ EY +++L L+ + F ES ++ +M Q+L+GL ++H
Sbjct: 68 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 125
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSP 775
+ L+ L + + F + +R +P S +LL+S
Sbjct: 126 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYR--APEVLLRST 183
Query: 776 RQTPALDMWAAGCILGD 826
+ +D+WA GCI+ +
Sbjct: 184 NYSSPIDVWAVGCIMAE 200
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRDLK NLL VKIADFGLAR + + T V T WYRAPE
Sbjct: 131 HRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPE 177
>U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein.
Length = 816
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 593 LHS 601
+HS
Sbjct: 173 MHS 175
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 178 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 237
Query: 777 D 779
+
Sbjct: 238 E 238
>U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein.
Length = 816
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 593 LHS 601
+HS
Sbjct: 173 MHS 175
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 178 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 237
Query: 777 D 779
+
Sbjct: 238 E 238
>U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein.
Length = 816
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 593 LHS 601
+HS
Sbjct: 173 MHS 175
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 178 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 237
Query: 777 D 779
+
Sbjct: 238 E 238
>U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein.
Length = 815
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 53 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 112
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 113 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 171
Query: 593 LHS 601
+HS
Sbjct: 172 MHS 174
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 177 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 236
Query: 777 D 779
+
Sbjct: 237 E 237
>BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein.
Length = 457
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/126 (29%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V K+ +G +VA+K+++ ++ LRE++ L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN-LREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+++LKEV+ R + ++ EY +++L L+ + + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
Query: 599 SN--FH 610
+ FH
Sbjct: 118 KHGFFH 123
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRD+K NLL VKIADFGLAR L + T V T WYRAPE
Sbjct: 123 HRDMKPENLLCMGPELVKIADFGLARELRSQP-PYTDYVSTRWYRAPE 169
>BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 593 LHS 601
+HS
Sbjct: 173 MHS 175
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 178 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 237
Query: 777 D 779
+
Sbjct: 238 E 238
>BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 593 LHS 601
+HS
Sbjct: 173 MHS 175
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 178 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 237
Query: 777 D 779
+
Sbjct: 238 E 238
>AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated protein
kinase 7 transcript variant 5 protein.
Length = 533
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 4/123 (3%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
E+E + IG G YG+V A+ + G VA+KK+ + LRE+++L +H+N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 425 IVQLKEVLVGR----SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
I+ +K++L +S+++ ++ E DL ++ + S P T V+ + Q+L+GLKY
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII-HSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 593 LHS 601
+HS
Sbjct: 173 MHS 175
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWL-GAPARS---ATPRVVTLWYRAPEYFCSHH 776
++HRDLK SNLL+ + +KI DFG+AR L +PA T V T WYRAPE S H
Sbjct: 178 VIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLH 237
Query: 777 D 779
+
Sbjct: 238 E 238
>AL024498-4|CAB75823.1| 623|Homo sapiens protein ( ovel
serine/threonine-proteinila) (Deafglial cells missing
homolog 2 (Drosophila)).).
Length = 623
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/126 (29%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V K+ +G +VA+K+++ ++ LRE++ L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN-LREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+++LKEV+ R + ++ EY +++L L+ + + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
Query: 599 SN--FH 610
+ FH
Sbjct: 118 KHGFFH 123
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRD+K NLL VKIADFGLAR L + T V T WYRAPE
Sbjct: 123 HRDMKPENLLCMGPELVKIADFGLARELRSQP-PYTDYVSTRWYRAPE 169
>AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associated
kinase protein.
Length = 623
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/126 (29%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V K+ +G +VA+K+++ ++ LRE++ L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN-LREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+++LKEV+ R + ++ EY +++L L+ + + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
Query: 599 SN--FH 610
+ FH
Sbjct: 118 KHGFFH 123
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRD+K NLL VKIADFGLAR L + T V T WYRAPE
Sbjct: 123 HRDMKPENLLCMGPELVKIADFGLARELRSQP-PYTDYVSTRWYRAPE 169
>AL162586-8|CAI39767.1| 194|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 194
Score = 74.5 bits (175), Expect = 4e-13
Identities = 32/65 (49%), Positives = 49/65 (75%)
Frame = +2
Query: 230 CRFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMS 409
C V ++EKL +IG+GT+G V++A+++ G VALKKV M+ EK+G P++ LREI++L
Sbjct: 130 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 189
Query: 410 CRHEN 424
+HEN
Sbjct: 190 LKHEN 194
>U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein
kinase, type 4 protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 74.1 bits (174), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A++ +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein.
Length = 873
Score = 73.7 bits (173), Expect = 7e-13
Identities = 38/119 (31%), Positives = 69/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
+FE + RIG GTYG VY+A+N G + A+K ++++ +D + +EI ++ C+H N
Sbjct: 15 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQ--QEIIMMKDCKHPN 72
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R + +++ ME+C + +++ P +E Q+ + + L+GL YLHS
Sbjct: 73 IVAYFGSYLRR--DKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHS 129
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/49 (42%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG++ + A + T ++ APE
Sbjct: 133 MHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPE 181
>AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein.
Length = 873
Score = 73.7 bits (173), Expect = 7e-13
Identities = 38/119 (31%), Positives = 69/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
+FE + RIG GTYG VY+A+N G + A+K ++++ +D + +EI ++ C+H N
Sbjct: 15 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQ--QEIIMMKDCKHPN 72
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R + +++ ME+C + +++ P +E Q+ + + L+GL YLHS
Sbjct: 73 IVAYFGSYLRR--DKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHS 129
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/49 (42%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG++ + A + T ++ APE
Sbjct: 133 MHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPE 181
>AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein.
Length = 894
Score = 73.7 bits (173), Expect = 7e-13
Identities = 38/119 (31%), Positives = 69/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
+FE + RIG GTYG VY+A+N G + A+K ++++ +D + +EI ++ C+H N
Sbjct: 15 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQ--QEIIMMKDCKHPN 72
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R + +++ ME+C + +++ P +E Q+ + + L+GL YLHS
Sbjct: 73 IVAYFGSYLRR--DKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHS 129
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/49 (42%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG++ + A + T ++ APE
Sbjct: 133 MHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPE 181
>AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase
related protein kinase protein.
Length = 884
Score = 73.7 bits (173), Expect = 7e-13
Identities = 38/119 (31%), Positives = 69/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
+FE + RIG GTYG VY+A+N G + A+K ++++ +D + +EI ++ C+H N
Sbjct: 5 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQ--QEIIMMKDCKHPN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R + +++ ME+C + +++ P +E Q+ + + L+GL YLHS
Sbjct: 63 IVAYFGSYLRR--DKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHS 119
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/49 (42%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG++ + A + T ++ APE
Sbjct: 123 MHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPE 171
>AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein.
Length = 712
Score = 73.7 bits (173), Expect = 7e-13
Identities = 38/119 (31%), Positives = 69/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
+FE + RIG GTYG VY+A+N G + A+K ++++ +D + +EI ++ C+H N
Sbjct: 15 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQ--QEIIMMKDCKHPN 72
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R + +++ ME+C + +++ P +E Q+ + + L+GL YLHS
Sbjct: 73 IVAYFGSYLRR--DKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHS 129
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/49 (42%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG++ + A + T ++ APE
Sbjct: 133 MHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPE 181
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 72.5 bits (170), Expect = 2e-12
Identities = 51/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++E L +GEG+YG+V + +NK G IVA+KK + + +REI++L RHEN
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+V L EV + + +L E+ + + L+ + V+ + Q++ G+ + HS+
Sbjct: 63 LVNLLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH 120
Query: 605 --FHCA*GLEGV-QSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H E + S +LC F + + PG+ +L+
Sbjct: 121 NIIHRDIKPENILVSQSGVVKLCD---FGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 776 RQTPALDMWAAGCIL 820
+ A+D+WA GC++
Sbjct: 178 KYGKAVDVWAIGCLV 192
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/50 (54%), Positives = 33/50 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRD+K N+L++ G VK+ DFG AR L AP T V T WYRAPE
Sbjct: 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPE 171
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 72.5 bits (170), Expect = 2e-12
Identities = 51/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++E L +GEG+YG+V + +NK G IVA+KK + + +REI++L RHEN
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+V L EV + + +L E+ + + L+ + V+ + Q++ G+ + HS+
Sbjct: 63 LVNLLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH 120
Query: 605 --FHCA*GLEGV-QSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H E + S +LC F + + PG+ +L+
Sbjct: 121 NIIHRDIKPENILVSQSGVVKLCD---FGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 776 RQTPALDMWAAGCIL 820
+ A+D+WA GC++
Sbjct: 178 KYGKAVDVWAIGCLV 192
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/50 (54%), Positives = 33/50 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRD+K N+L++ G VK+ DFG AR L AP T V T WYRAPE
Sbjct: 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPE 171
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 72.5 bits (170), Expect = 2e-12
Identities = 51/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++E L +GEG+YG+V + +NK G IVA+KK + + +REI++L RHEN
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+V L EV + + +L E+ + + L+ + V+ + Q++ G+ + HS+
Sbjct: 63 LVNLLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH 120
Query: 605 --FHCA*GLEGV-QSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H E + S +LC F + + PG+ +L+
Sbjct: 121 NIIHRDIKPENILVSQSGVVKLCD---FGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 776 RQTPALDMWAAGCIL 820
+ A+D+WA GC++
Sbjct: 178 KYGKAVDVWAIGCLV 192
Score = 62.5 bits (145), Expect = 2e-09
Identities = 27/50 (54%), Positives = 33/50 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRD+K N+L++ G VK+ DFG AR L AP T V T WYRAPE
Sbjct: 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPE 171
>AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase
protein.
Length = 632
Score = 72.5 bits (170), Expect = 2e-12
Identities = 49/197 (24%), Positives = 96/197 (48%), Gaps = 1/197 (0%)
Frame = +2
Query: 239 VGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRH 418
+ + + ++G+GTYG V ++ +G ++A+KK++ RE++ L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNQREVKSLKKLNH 59
Query: 419 ENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
N+V+LKEV+ R + ++ EY +++L L+ + F ES ++ +M Q+L+GL ++H
Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
Query: 599 SNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVR-RPGQKCNASCCHLMV*GARILLQSP 775
L+ L + + F + +R +P S +LL+S
Sbjct: 118 KLGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYR--APEVLLRST 175
Query: 776 RQTPALDMWAAGCILGD 826
+ +D+WA GCI+ +
Sbjct: 176 NYSSPIDVWAVGCIMAE 192
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/48 (56%), Positives = 29/48 (60%)
Frame = +3
Query: 615 HRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
HRDLK NLL VKIADFGLAR + + T V T WYRAPE
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPE 169
>Z48970-1|CAA88834.1| 303|Homo sapiens orf protein.
Length = 303
Score = 72.1 bits (169), Expect = 2e-12
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 10/203 (4%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRM---DVEKDGLPLSGLREIQVLM---S 409
+E + IG G YG VY+A + +G VALK VR+ GLP+S +RE+ +L +
Sbjct: 6 YEPVAEIGVGAYGTVYKACDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 410 CRHENIVQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQ-VKCLMLQVL 577
H N+V+L +V + + L E+ +QDL + LD P ++ +K LM Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 578 KGLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GAR 757
+GL +LH+N L+ + + F + + L
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-MALTPVVVTLWYRAPE 184
Query: 758 ILLQSPRQTPALDMWAAGCILGD 826
+LLQS TP +DMW+ GCI +
Sbjct: 185 VLLQSTYATP-VDMWSVGCIFAE 206
Score = 64.5 bits (150), Expect = 4e-10
Identities = 32/50 (64%), Positives = 38/50 (76%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
IVHRDLK N+L+T G VK+ADFGLAR + + + TP VVTLWYRAPE
Sbjct: 136 IVHRDLKPENILVTSGGTVKLADFGLAR-IYSYQMALTPVVVTLWYRAPE 184
>Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase
protein.
Length = 355
Score = 72.1 bits (169), Expect = 2e-12
Identities = 55/199 (27%), Positives = 92/199 (46%), Gaps = 6/199 (3%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ +L IGEG YG+V A + + VA+KK+ E LREIQ+L+ RHEN+
Sbjct: 18 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 76
Query: 428 VQLKEVLVGRSLES---IFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ ++++L +LE+ +++ + E DL LL S + + + Q+L+GLKY+H
Sbjct: 77 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRGLKYIH 134
Query: 599 SNFHCA*GLEGVQSSFN---**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
S L+ N ++C R + I+L
Sbjct: 135 SANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN 194
Query: 770 SPRQTPALDMWAAGCILGD 826
S T ++D+W+ GCIL +
Sbjct: 195 SKGYTKSIDIWSVGCILAE 213
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/54 (50%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLL+ +KI DFGLAR + P T V T WYRAPE
Sbjct: 138 VLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 190
>M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein.
Length = 366
Score = 72.1 bits (169), Expect = 2e-12
Identities = 55/199 (27%), Positives = 92/199 (46%), Gaps = 6/199 (3%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ +L IGEG YG+V A + + VA+KK+ E LREIQ+L+ RHEN+
Sbjct: 29 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 87
Query: 428 VQLKEVLVGRSLES---IFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ ++++L +LE+ +++ + E DL LL S + + + Q+L+GLKY+H
Sbjct: 88 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRGLKYIH 145
Query: 599 SNFHCA*GLEGVQSSFN---**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
S L+ N ++C R + I+L
Sbjct: 146 SANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN 205
Query: 770 SPRQTPALDMWAAGCILGD 826
S T ++D+W+ GCIL +
Sbjct: 206 SKGYTKSIDIWSVGCILAE 224
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/54 (50%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLL+ +KI DFGLAR + P T V T WYRAPE
Sbjct: 149 VLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 201
>BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein.
Length = 812
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/120 (34%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
FE L R+G GTYG VY+A++ + A+K V++D D L +EI +L CRH N+
Sbjct: 16 FELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQ--QEITILRECRHPNV 73
Query: 428 VQLKEVLVGRSL--ESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
V +G L + +++ ME+C + + + P E Q+ + + LKGL +LHS
Sbjct: 74 V----AYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHS 129
Score = 44.0 bits (99), Expect = 7e-04
Identities = 22/49 (44%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +NLLLT +G VK+ADFG++ L A + T ++ APE
Sbjct: 133 IHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPE 181
>BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated protein
kinase 3 protein.
Length = 379
Score = 72.1 bits (169), Expect = 2e-12
Identities = 55/199 (27%), Positives = 92/199 (46%), Gaps = 6/199 (3%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ +L IGEG YG+V A + + VA+KK+ E LREIQ+L+ RHEN+
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 100
Query: 428 VQLKEVLVGRSLES---IFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ ++++L +LE+ +++ + E DL LL S + + + Q+L+GLKY+H
Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRGLKYIH 158
Query: 599 SNFHCA*GLEGVQSSFN---**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQ 769
S L+ N ++C R + I+L
Sbjct: 159 SANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN 218
Query: 770 SPRQTPALDMWAAGCILGD 826
S T ++D+W+ GCIL +
Sbjct: 219 SKGYTKSIDIWSVGCILAE 237
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/54 (50%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLL+ +KI DFGLAR + P T V T WYRAPE
Sbjct: 162 VLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 214
>X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine
kinase protein.
Length = 379
Score = 71.7 bits (168), Expect = 3e-12
Identities = 41/121 (33%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ +L IGEG YG+V A + + VA+KK+ E LREIQ+L+ RHEN+
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 100
Query: 428 VQLKEVLVGRSLES---IFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ ++++L +LE+ +++ + E DL LL S + + + Q+L+GLKY+H
Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRGLKYIH 158
Query: 599 S 601
S
Sbjct: 159 S 159
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/54 (50%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 162 VLHRDLKPSNLLSNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 214
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 71.7 bits (168), Expect = 3e-12
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 3/194 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E L ++GEG+YG V + K+K G IVA+ K+ + + + +REI+ L HEN+
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHHENL 62
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN- 604
V L EV R + I L E+ + + L + +++ + Q+L+ + YLHSN
Sbjct: 63 VNLIEVF--RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN 120
Query: 605 -FHCA*GLEGV-QSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
H E + S +LC F + + PG ++L+
Sbjct: 121 IIHRDIKPENILVSQSGITKLCD---FGFARTLAAPGDIYTDYVATRWYRAPELVLKDTS 177
Query: 779 QTPALDMWAAGCIL 820
+D+WA GC++
Sbjct: 178 YGKPVDIWALGCMI 191
Score = 60.1 bits (139), Expect = 1e-08
Identities = 26/50 (52%), Positives = 32/50 (64%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRD+K N+L++ G K+ DFG AR L AP T V T WYRAPE
Sbjct: 121 IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPE 170
>AY033608-1|AAK52330.1| 335|Homo sapiens extracellular
signal-related kinase 1c protein.
Length = 335
Score = 71.7 bits (168), Expect = 3e-12
Identities = 41/121 (33%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ +L IGEG YG+V A + + VA+KK+ E LREIQ+L+ RHEN+
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 100
Query: 428 VQLKEVLVGRSLES---IFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ ++++L +LE+ +++ + E DL LL S + + + Q+L+GLKY+H
Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRGLKYIH 158
Query: 599 S 601
S
Sbjct: 159 S 159
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/54 (50%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 162 VLHRDLKPSNLLSNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 214
>AY033607-1|AAK52329.1| 357|Homo sapiens extracellular
signal-related kinase 1b protein.
Length = 357
Score = 71.7 bits (168), Expect = 3e-12
Identities = 41/121 (33%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ +L IGEG YG+V A + + VA+KK+ E LREIQ+L+ RHEN+
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 100
Query: 428 VQLKEVLVGRSLES---IFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ ++++L +LE+ +++ + E DL LL S + + + Q+L+GLKY+H
Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRGLKYIH 158
Query: 599 S 601
S
Sbjct: 159 S 159
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/54 (50%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 162 VLHRDLKPSNLLSNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 214
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 71.7 bits (168), Expect = 3e-12
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 3/194 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E L ++GEG+YG V + K+K G IVA+ K+ + + + +REI+ L HEN+
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHHENL 62
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN- 604
V L EV R + I L E+ + + L + +++ + Q+L+ + YLHSN
Sbjct: 63 VNLIEVF--RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN 120
Query: 605 -FHCA*GLEGV-QSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSPR 778
H E + S +LC F + + PG ++L+
Sbjct: 121 IIHRDIKPENILVSQSGITKLCD---FGFARTLAAPGDIYTDYVATRWYRAPELVLKDTS 177
Query: 779 QTPALDMWAAGCIL 820
+D+WA GC++
Sbjct: 178 YGKPVDIWALGCMI 191
Score = 60.1 bits (139), Expect = 1e-08
Identities = 26/50 (52%), Positives = 32/50 (64%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRD+K N+L++ G K+ DFG AR L AP T V T WYRAPE
Sbjct: 121 IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPE 170
>AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated
kinase 8 delta protein.
Length = 254
Score = 71.3 bits (167), Expect = 4e-12
Identities = 59/205 (28%), Positives = 95/205 (46%), Gaps = 7/205 (3%)
Frame = +2
Query: 233 RFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS-GLREIQVLMS 409
R V + ++G+G YGIV++A ++ G +VA+KK+ D +D REI +L
Sbjct: 8 RIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKI-FDAFRDKTDAQRTFREITLLQE 66
Query: 410 C-RHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGL 586
H NI+ L +V+ + I+L E+ + DL +++ + +V+ + Q+L+
Sbjct: 67 FGDHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVI-RKGGLLQDVRVRSIFYQLLRAT 125
Query: 587 KYLHSN--FHCA*GLEGVQSSFN-**RLCQNS*FRS-SSLVRRP-GQKCNASCCHLMV*G 751
++LHS H V N +LC RS L P Q
Sbjct: 126 RFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRA 185
Query: 752 ARILLQSPRQTPALDMWAAGCILGD 826
+LL S R T +DMW+ GCILG+
Sbjct: 186 PEVLLSSHRYTLGVDMWSLGCILGE 210
Score = 54.4 bits (125), Expect = 5e-07
Identities = 31/61 (50%), Positives = 36/61 (59%), Gaps = 5/61 (8%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLG----APA-RSATPRVVTLWYRAPEYFCSH 773
+VHRD K SN+LL VK+ DFGLAR LG P ++ T V T WYRAPE S
Sbjct: 133 VVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSS 192
Query: 774 H 776
H
Sbjct: 193 H 193
>Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-like 6
(CDK8-like) protein.
Length = 502
Score = 70.9 bits (166), Expect = 5e-12
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+A+ K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + S ++L +Y E DL AS + S VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein.
Length = 846
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/119 (31%), Positives = 68/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++E + R+G GTYG VY+A+N G + A+K ++++ D + +EI ++ C+H N
Sbjct: 19 DYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQ--QEIFMVKECKHCN 76
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R E +++ MEYC + +++ P +E Q+ + + L+GL YLH+
Sbjct: 77 IVAYFGSYLSR--EKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHT 133
Score = 46.0 bits (104), Expect = 2e-04
Identities = 22/49 (44%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG+A + A + T ++ APE
Sbjct: 137 MHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPE 185
>U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein.
Length = 819
Score = 70.9 bits (166), Expect = 5e-12
Identities = 41/120 (34%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
FE L R+G GTYG VY+A++ + A+K V++D D L +EI +L CRH N+
Sbjct: 15 FELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQ--QEITILRECRHPNV 72
Query: 428 VQLKEVLVGRSL--ESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
V +G L + +++ ME+C + + + P E Q+ + + LKGL +LHS
Sbjct: 73 V----AYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCRERLKGLHHLHS 128
Score = 44.0 bits (99), Expect = 7e-04
Identities = 22/49 (44%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +NLLLT +G VK+ADFG++ L A + T ++ APE
Sbjct: 132 IHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPE 180
>BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 70.9 bits (166), Expect = 5e-12
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+A+ K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + S ++L +Y E DL AS + S VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated protein
kinase kinase kinase kinase 5 protein.
Length = 846
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/119 (31%), Positives = 68/119 (57%)
Frame = +2
Query: 245 EFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHEN 424
++E + R+G GTYG VY+A+N G + A+K ++++ D + +EI ++ C+H N
Sbjct: 19 DYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQ--QEIFMVKECKHCN 76
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
IV + R E +++ MEYC + +++ P +E Q+ + + L+GL YLH+
Sbjct: 77 IVAYFGSYLSR--EKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHT 133
Score = 46.0 bits (104), Expect = 2e-04
Identities = 22/49 (44%), Positives = 32/49 (65%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K +N+LLTD G VK+ADFG+A + A + T ++ APE
Sbjct: 137 MHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPE 185
>AY065978-1|AAL40897.1| 544|Homo sapiens extracellular
signal-regulated kinase 8 protein.
Length = 544
Score = 70.9 bits (166), Expect = 5e-12
Identities = 59/205 (28%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Frame = +2
Query: 233 RFVGEFEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLS-GLREIQVLMS 409
R V + ++G+G YGIV++A ++ G +VA+KK+ D +D REI +L
Sbjct: 8 RIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKI-FDAFRDKTDAQRTFREITLLQE 66
Query: 410 C-RHENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGL 586
H NI+ L +V+ + I+L E+ + DL +++ + V+ + Q+L+
Sbjct: 67 FGDHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVI-RKGGLLQDVHVRSIFYQLLRAT 125
Query: 587 KYLHSN--FHCA*GLEGVQSSFN-**RLCQNS*FRS-SSLVRRP-GQKCNASCCHLMV*G 751
++LHS H V N +LC RS L P Q
Sbjct: 126 RFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRA 185
Query: 752 ARILLQSPRQTPALDMWAAGCILGD 826
+LL S R T +DMW+ GCILG+
Sbjct: 186 PEVLLSSHRYTLGVDMWSLGCILGE 210
Score = 54.4 bits (125), Expect = 5e-07
Identities = 31/61 (50%), Positives = 36/61 (59%), Gaps = 5/61 (8%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLG----APA-RSATPRVVTLWYRAPEYFCSH 773
+VHRD K SN+LL VK+ DFGLAR LG P ++ T V T WYRAPE S
Sbjct: 133 VVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSS 192
Query: 774 H 776
H
Sbjct: 193 H 193
>AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase
protein.
Length = 502
Score = 70.9 bits (166), Expect = 5e-12
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+A+ K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + S ++L +Y E DL AS + S VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 70.9 bits (166), Expect = 5e-12
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+A+ K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + S ++L +Y E DL AS + S VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 70.9 bits (166), Expect = 5e-12
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+A+ K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + S ++L +Y E DL AS + S VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein.
Length = 501
Score = 70.9 bits (166), Expect = 5e-12
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+A+ K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 25 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 80
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + S ++L +Y E DL AS + S VK L+ Q+L G+ Y
Sbjct: 81 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 140
Query: 593 LHSNF 607
LH+N+
Sbjct: 141 LHANW 145
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 145 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 202
>X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein.
Length = 464
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + VK L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 7/58 (12%)
Frame = +3
Query: 606 FIVHRDLKVSNLLLT----DKGCVKIADFGLARWLGAPARSAT---PRVVTLWYRAPE 758
+++HRDLK +N+L+ ++G VKIAD G AR +P + P VVT WYRAPE
Sbjct: 146 WVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
>AL353572-3|CAM17658.1| 338|Homo sapiens cell cycle related kinase
protein.
Length = 338
Score = 69.3 bits (162), Expect = 2e-11
Identities = 46/130 (35%), Positives = 68/130 (52%), Gaps = 14/130 (10%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKA-------------NGSIVALKKVRMDVEKDGLPLSGLREIQ 397
L RIGEG +GIV++AK+ G IVALKKV + +DG P LREI+
Sbjct: 7 LGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQALREIK 66
Query: 398 VLMSCR-HENIVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQV 574
L ++ +VQLK V L+ E+ DLA ++ + P ++QVK + +
Sbjct: 67 ALQEMEDNQYVVQLKAVFPHGG--GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQML 124
Query: 575 LKGLKYLHSN 604
LKG+ + H+N
Sbjct: 125 LKGVAFCHAN 134
Score = 44.8 bits (101), Expect = 4e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +3
Query: 588 SICIPTFIVHRDLKVSNLLLTDKGCVKIADFGLAR 692
+ C IVHRDLK +NLL++ G +KIADFGLAR
Sbjct: 129 AFCHANNIVHRDLKPANLLISASGQLKIADFGLAR 163
>AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragment)
variant protein.
Length = 307
Score = 69.3 bits (162), Expect = 2e-11
Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 28 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 87
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ QVLKGLKY+HS
Sbjct: 88 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQVLKGLKYIHS 140
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 143 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 193
>AY702976-1|AAU29339.1| 164|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 164
Score = 68.5 bits (160), Expect = 3e-11
Identities = 40/125 (32%), Positives = 66/125 (52%), Gaps = 10/125 (8%)
Frame = +2
Query: 263 RIGEGTYGIVYRAKNK--ANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
++G GTYG VY+AK K + ALK++ E G+ +S REI +L +H N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLQELKHPNVISL 81
Query: 437 KEVLVGRSLESIFLSMEYCEQDL--------ASLLDNMSSPFTESQVKCLMLQVLKGLKY 592
++V + + ++L +Y E DL AS + V+ L+ Q+L G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLRHIIKFHRASKANKKPVQLPRGMVESLLYQILDGIHY 141
Query: 593 LHSNF 607
LH+N+
Sbjct: 142 LHANW 146
>Z95152-2|CAB08438.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein
kinase-4 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>BC085196-1|AAH85196.1| 257|Homo sapiens MAPK13 protein protein.
Length = 257
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated protein
kinase p38delta protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK+ + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +KI DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein.
Length = 360
Score = 67.7 bits (158), Expect = 5e-11
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L+ IGEG YG+V A + N VA+KK+ E LREI++L+ RHENI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENI 83
Query: 428 VQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ + +++ ++E +++ + E DL LL + + + + Q+L+GLKY+H
Sbjct: 84 IGINDIIQAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRGLKYIH 141
Query: 599 S 601
S
Sbjct: 142 S 142
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/54 (51%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 145 VLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPE 197
>BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 67.7 bits (158), Expect = 5e-11
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L+ IGEG YG+V A + N VA+KK+ E LREI++L+ RHENI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRSRHENI 83
Query: 428 VQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ + +++ ++E +++ + E DL LL + + + + Q+L+GLKY+H
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRGLKYIH 141
Query: 599 S 601
S
Sbjct: 142 S 142
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/54 (50%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLLL ++I DFGLAR + P T V T WYRAPE
Sbjct: 145 VLHRDLKPSNLLLNTTCDLEICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPE 197
>Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase
protein.
Length = 348
Score = 67.3 bits (157), Expect = 6e-11
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L+ IGEG YG+V A + N VA+KK+ E LREI++L+ RHENI
Sbjct: 13 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENI 71
Query: 428 VQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ + +++ ++E +++ + E DL LL + + + + Q+L+GLKY+H
Sbjct: 72 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRGLKYIH 129
Query: 599 S 601
S
Sbjct: 130 S 130
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/54 (51%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 133 VLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPE 185
>M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein.
Length = 360
Score = 67.3 bits (157), Expect = 6e-11
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L+ IGEG YG+V A + N VA+KK+ E LREI++L+ RHENI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENI 83
Query: 428 VQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ + +++ ++E +++ + E DL LL + + + + Q+L+GLKY+H
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRGLKYIH 141
Query: 599 S 601
S
Sbjct: 142 S 142
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/54 (51%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 145 VLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPE 197
>DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 67.3 bits (157), Expect = 6e-11
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L+ IGEG YG+V A + N VA+KK+ E LREI++L+ RHENI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENI 83
Query: 428 VQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ + +++ ++E +++ + E DL LL + + + + Q+L+GLKY+H
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRGLKYIH 141
Query: 599 S 601
S
Sbjct: 142 S 142
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/54 (51%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 145 VLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPE 197
>BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 67.3 bits (157), Expect = 6e-11
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L+ IGEG YG+V A + N VA+KK+ E LREI++L+ RHENI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENI 83
Query: 428 VQLKEVLVGRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
+ + +++ ++E +++ + E DL LL + + + + Q+L+GLKY+H
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRGLKYIH 141
Query: 599 S 601
S
Sbjct: 142 S 142
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/54 (51%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARS----ATPRVVTLWYRAPE 758
++HRDLK SNLLL +KI DFGLAR + P T V T WYRAPE
Sbjct: 145 VLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPE 197
>AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated
protein kinase protein.
Length = 365
Score = 66.9 bits (156), Expect = 8e-11
Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
Frame = +2
Query: 266 IGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQLKEV 445
+G G YG V A +K +G VA+KK + + RE+ +L +HEN++ L +V
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKPSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 446 LVG----RSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHS 601
R+ +L M + + DL + M F+E +++ L+ Q+LKGLKY+HS
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKI---MGMEFSEEKIQYLVYQMLKGLKYIHS 143
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/54 (50%), Positives = 32/54 (59%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPEYFCS 770
+VHRDLK NL + + +K+ DFGLAR A T VVT WYRAPE S
Sbjct: 146 VVHRDLKPGNLAVNEDCELKVLDFGLARHADA---EMTGYVVTRWYRAPEVILS 196
>Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein
kinase-3 protein.
Length = 367
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L +G G YG V A + G+ VA+KK+ + + RE+++L RHEN+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 428 VQLKEVLV-GRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYL 595
+ L +V +L+ +L M + DL L+ + E +++ L+ Q+LKGL+Y+
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKH--EKLGEDRIQFLVYQMLKGLRYI 144
Query: 596 HSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H+ L+ + N C+ L R+ + ++L
Sbjct: 145 HAAGIIHRDLKPGNLAVN--EDCELK-ILDFGLARQADSEMTGYVVTRWYRAPEVILNWM 201
Query: 776 RQTPALDMWAAGCILGD 826
R T +D+W+ GCI+ +
Sbjct: 202 RYTQTVDIWSVGCIMAE 218
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/50 (52%), Positives = 31/50 (62%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NL + + +KI DFGLAR + T VVT WYRAPE
Sbjct: 149 IIHRDLKPGNLAVNEDCELKILDFGLARQADS---EMTGYVVTRWYRAPE 195
>U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein.
Length = 367
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L +G G YG V A + G+ VA+KK+ + + RE+++L RHEN+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 428 VQLKEVLV-GRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYL 595
+ L +V +L+ +L M + DL L+ + E +++ L+ Q+LKGL+Y+
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKH--EKLGEDRIQFLVYQMLKGLRYI 144
Query: 596 HSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H+ L+ + N C+ L R+ + ++L
Sbjct: 145 HAAGIIHRDLKPGNLAVN--EDCELK-ILDFGLARQADSEMTGYVVTRWYRAPEVILNWM 201
Query: 776 RQTPALDMWAAGCILGD 826
R T +D+W+ GCI+ +
Sbjct: 202 RYTQTVDIWSVGCIMAE 218
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/50 (52%), Positives = 31/50 (62%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NL + + +KI DFGLAR + T VVT WYRAPE
Sbjct: 149 IIHRDLKPGNLAVNEDCELKILDFGLARQADS---EMTGYVVTRWYRAPE 195
>BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L +G G YG V A + G+ VA+KK+ + + RE+++L RHEN+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 428 VQLKEVLV-GRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYL 595
+ L +V +L+ +L M + DL L+ + E +++ L+ Q+LKGL+Y+
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKH--EKLGEDRIQFLVYQMLKGLRYI 144
Query: 596 HSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H+ L+ + N C+ L R+ + ++L
Sbjct: 145 HAAGIIHRDLKPGNLAVN--EDCELK-ILDFGLARQADSEMTGYVVTRWYRAPEVILNWM 201
Query: 776 RQTPALDMWAAGCILGD 826
R T +D+W+ GCI+ +
Sbjct: 202 RYTQTVDIWSVGCIMAE 218
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/50 (52%), Positives = 31/50 (62%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NL + + +KI DFGLAR + T VVT WYRAPE
Sbjct: 149 IIHRDLKPGNLAVNEDCELKILDFGLARQADS---EMTGYVVTRWYRAPE 195
>AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+ L +G G YG V A + G+ VA+KK+ + + RE+++L RHEN+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 428 VQLKEVLV-GRSLE---SIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYL 595
+ L +V +L+ +L M + DL L+ + E +++ L+ Q+LKGL+Y+
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKH--EKLGEDRIQFLVYQMLKGLRYI 144
Query: 596 HSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV*GARILLQSP 775
H+ L+ + N C+ L R+ + ++L
Sbjct: 145 HAAGIIHRDLKPGNLAVN--EDCELK-ILDFGLARQADSEMTGYVVTRWYRAPEVILNWM 201
Query: 776 RQTPALDMWAAGCILGD 826
R T +D+W+ GCI+ +
Sbjct: 202 RYTQTVDIWSVGCIMAE 218
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/50 (52%), Positives = 31/50 (62%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK NL + + +KI DFGLAR + T VVT WYRAPE
Sbjct: 149 IIHRDLKPGNLAVNEDCELKILDFGLARQADS---EMTGYVVTRWYRAPE 195
>X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein.
Length = 721
Score = 66.1 bits (154), Expect = 1e-10
Identities = 60/206 (29%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L +G G G+V+ A + VA+KK+ + + LREI+++ H+NIV++
Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKV 80
Query: 437 KEVL----------VGR--SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLK 580
E+L VG L S+++ EY E DLA++L+ P E + M Q+L+
Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLLEEHARLFMYQLLR 138
Query: 581 GLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV----* 748
GLKY+HS L+ N L + + P +V
Sbjct: 139 GLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYR 198
Query: 749 GARILLQSPRQTPALDMWAAGCILGD 826
R+LL T A+DMWAAGCI +
Sbjct: 199 SPRLLLSPNNYTKAIDMWAAGCIFAE 224
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLL-TDKGCVKIADFGLARWLG---APARSATPRVVTLWYRAPEYFCS 770
++HRDLK +NL + T+ +KI DFGLAR + + + +VT WYR+P S
Sbjct: 148 VLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS 205
>L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein.
Length = 721
Score = 66.1 bits (154), Expect = 1e-10
Identities = 60/206 (29%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L +G G G+V+ A + VA+KK+ + + LREI+++ H+NIV++
Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKV 80
Query: 437 KEVL----------VGR--SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLK 580
E+L VG L S+++ EY E DLA++L+ P E + M Q+L+
Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLLEEHARLFMYQLLR 138
Query: 581 GLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV----* 748
GLKY+HS L+ N L + + P +V
Sbjct: 139 GLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYR 198
Query: 749 GARILLQSPRQTPALDMWAAGCILGD 826
R+LL T A+DMWAAGCI +
Sbjct: 199 SPRLLLSPNNYTKAIDMWAAGCIFAE 224
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLL-TDKGCVKIADFGLARWLG---APARSATPRVVTLWYRAPEYFCS 770
++HRDLK +NL + T+ +KI DFGLAR + + + +VT WYR+P S
Sbjct: 148 VLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS 205
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 46 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 103
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 104 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 161
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 163 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 212
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated protein
kinase 6 protein.
Length = 721
Score = 66.1 bits (154), Expect = 1e-10
Identities = 60/206 (29%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L +G G G+V+ A + VA+KK+ + + LREI+++ H+NIV++
Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKV 80
Query: 437 KEVL----------VGR--SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLK 580
E+L VG L S+++ EY E DLA++L+ P E + M Q+L+
Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLLEEHARLFMYQLLR 138
Query: 581 GLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV----* 748
GLKY+HS L+ N L + + P +V
Sbjct: 139 GLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYR 198
Query: 749 GARILLQSPRQTPALDMWAAGCILGD 826
R+LL T A+DMWAAGCI +
Sbjct: 199 SPRLLLSPNNYTKAIDMWAAGCIFAE 224
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLL-TDKGCVKIADFGLARWLG---APARSATPRVVTLWYRAPEYFCS 770
++HRDLK +NL + T+ +KI DFGLAR + + + +VT WYR+P S
Sbjct: 148 VLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS 205
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein.
Length = 721
Score = 66.1 bits (154), Expect = 1e-10
Identities = 60/206 (29%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Frame = +2
Query: 257 LNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENIVQL 436
L +G G G+V+ A + VA+KK+ + + LREI+++ H+NIV++
Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQS--VKHALREIKIIRRLDHDNIVKV 80
Query: 437 KEVL----------VGR--SLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLK 580
E+L VG L S+++ EY E DLA++L+ P E + M Q+L+
Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLLEEHARLFMYQLLR 138
Query: 581 GLKYLHSNFHCA*GLEGVQSSFN**RLCQNS*FRSSSLVRRPGQKCNASCCHLMV----* 748
GLKY+HS L+ N L + + P +V
Sbjct: 139 GLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYR 198
Query: 749 GARILLQSPRQTPALDMWAAGCILGD 826
R+LL T A+DMWAAGCI +
Sbjct: 199 SPRLLLSPNNYTKAIDMWAAGCIFAE 224
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Frame = +3
Query: 609 IVHRDLKVSNLLL-TDKGCVKIADFGLARWLG---APARSATPRVVTLWYRAPEYFCS 770
++HRDLK +NL + T+ +KI DFGLAR + + + +VT WYR+P S
Sbjct: 148 VLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLS 205
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 66.1 bits (154), Expect = 1e-10
Identities = 38/120 (31%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
+E + +G+G +G VY+A+NK S++A KV +D + + + EI +L SC H NI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKET-SVLAAAKV-IDTKSEEELEDYMVEIDILASCDHPNI 91
Query: 428 VQLKEVLVGRSLESIFLSMEYCEQD-LASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
V+L + + ++++ +E+C + +++ + P TESQ++ + Q L L YLH N
Sbjct: 92 VKLLDAFYYEN--NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Score = 39.1 bits (87), Expect = 0.019
Identities = 19/50 (38%), Positives = 29/50 (58%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
I+HRDLK N+L T G +K+ADFG++ + + T ++ APE
Sbjct: 151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+ L ++GEG+YG VY+A +K G IVA+K+V VE D + ++EI ++ C ++
Sbjct: 30 FDVLEKLGEGSYGSVYKAIHKETGQIVAIKQV--PVESDLQEI--IKEISIMQQCDSPHV 85
Query: 428 VQLKEVLVGRSLESIFLSMEYC-EQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
V+ + +++ MEYC ++ ++ + TE ++ ++ LKGL+YLH
Sbjct: 86 VKYYGSYFKNT--DLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLH 141
Score = 40.3 bits (90), Expect = 0.008
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+LL +G K+ADFG+A L + T ++ APE
Sbjct: 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 194
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+ L ++GEG+YG VY+A +K G IVA+K+V VE D + ++EI ++ C ++
Sbjct: 30 FDVLEKLGEGSYGSVYKAIHKETGQIVAIKQV--PVESDLQEI--IKEISIMQQCDSPHV 85
Query: 428 VQLKEVLVGRSLESIFLSMEYC-EQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
V+ + +++ MEYC ++ ++ + TE ++ ++ LKGL+YLH
Sbjct: 86 VKYYGSYFKNT--DLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLH 141
Score = 40.3 bits (90), Expect = 0.008
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+LL +G K+ADFG+A L + T ++ APE
Sbjct: 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 194
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+ L ++GEG+YG VY+A +K G IVA+K+V VE D + ++EI ++ C ++
Sbjct: 30 FDVLEKLGEGSYGSVYKAIHKETGQIVAIKQV--PVESDLQEI--IKEISIMQQCDSPHV 85
Query: 428 VQLKEVLVGRSLESIFLSMEYC-EQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
V+ + +++ MEYC ++ ++ + TE ++ ++ LKGL+YLH
Sbjct: 86 VKYYGSYFKNT--DLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLH 141
Score = 40.3 bits (90), Expect = 0.008
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+LL +G K+ADFG+A L + T ++ APE
Sbjct: 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 194
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSGLREIQVLMSCRHENI 427
F+ L ++GEG+YG VY+A +K G IVA+K+V VE D + ++EI ++ C ++
Sbjct: 30 FDVLEKLGEGSYGSVYKAIHKETGQIVAIKQV--PVESDLQEI--IKEISIMQQCDSPHV 85
Query: 428 VQLKEVLVGRSLESIFLSMEYC-EQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLH 598
V+ + +++ MEYC ++ ++ + TE ++ ++ LKGL+YLH
Sbjct: 86 VKYYGSYFKNT--DLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLH 141
Score = 40.3 bits (90), Expect = 0.008
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +3
Query: 612 VHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
+HRD+K N+LL +G K+ADFG+A L + T ++ APE
Sbjct: 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 194
>BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 65.7 bits (153), Expect = 2e-10
Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 1/120 (0%)
Frame = +2
Query: 248 FEKLNRIGEGTYGIVYRAKNKANGSIVALKKVRMDVEKDGLPLSG-LREIQVLMSCRHEN 424
F L IG G++G VY A++ N +VA+KK+ ++ ++E++ L RH N
Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87
Query: 425 IVQLKEVLVGRSLESIFLSMEYCEQDLASLLDNMSSPFTESQVKCLMLQVLKGLKYLHSN 604
+Q + + + +L MEYC + LL+ P E ++ + L+GL YLHS+
Sbjct: 88 TIQYRGCYLRE--HTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSH 145
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/50 (46%), Positives = 33/50 (66%)
Frame = +3
Query: 609 IVHRDLKVSNLLLTDKGCVKIADFGLARWLGAPARSATPRVVTLWYRAPE 758
++HRD+K N+LL++ G VK+ DFG A + APA S V T ++ APE
Sbjct: 147 MIHRDVKAGNILLSEPGLVKLGDFGSAS-IMAPANSF---VGTPYWTAPE 192
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,311,878
Number of Sequences: 237096
Number of extensions: 2782236
Number of successful extensions: 14654
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 11306
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13608
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10315140830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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