Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-6046
(779 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 165 2e-40
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 165 2e-40
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 165 2e-40
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 165 2e-40
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 165 2e-40
AL132671-5|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 165 2e-40
AL132671-4|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 165 2e-40
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 110 5e-24
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 110 5e-24
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 110 5e-24
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 110 5e-24
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 110 5e-24
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 110 5e-24
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 110 5e-24
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 110 5e-24
AB275889-1|BAF73612.1| 1310|Homo sapiens EML4-ALK variant 2 prot... 110 5e-24
AB274722-1|BAF73611.1| 1059|Homo sapiens EML4-ALK variant 1 prot... 110 5e-24
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 110 5e-24
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 107 3e-23
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 107 3e-23
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 107 3e-23
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 105 1e-22
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 105 1e-22
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 105 1e-22
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 105 1e-22
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 103 5e-22
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 103 5e-22
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 103 5e-22
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 103 5e-22
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 103 5e-22
M27197-1|AAA86791.1| 118|Homo sapiens INSR protein. 103 7e-22
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 99 9e-21
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 99 9e-21
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 89 2e-17
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 88 4e-17
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 88 4e-17
AL596132-4|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AL596132-3|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AL445532-2|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AL445532-1|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AL390777-4|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AL390777-3|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 88 4e-17
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 88 4e-17
AB209118-1|BAD92355.1| 781|Homo sapiens BDNF/NT-3 growth factor... 88 4e-17
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 86 2e-16
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 85 2e-16
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 85 2e-16
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 85 2e-16
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 85 2e-16
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 85 2e-16
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 85 2e-16
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 85 2e-16
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 85 2e-16
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 85 2e-16
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 85 2e-16
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 85 2e-16
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 85 2e-16
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 85 2e-16
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 85 2e-16
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 84 5e-16
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 84 5e-16
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 84 5e-16
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 84 6e-16
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 84 6e-16
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 84 6e-16
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 84 6e-16
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 84 6e-16
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 84 6e-16
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 84 6e-16
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 84 6e-16
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 84 6e-16
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 84 6e-16
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 84 6e-16
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 84 6e-16
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 84 6e-16
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 83 8e-16
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 83 8e-16
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 83 8e-16
AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine ki... 83 8e-16
AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine ki... 83 8e-16
AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine ki... 83 8e-16
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 80 1e-14
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 80 1e-14
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 80 1e-14
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 80 1e-14
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 80 1e-14
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 80 1e-14
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 80 1e-14
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 80 1e-14
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 80 1e-14
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 80 1e-14
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 80 1e-14
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 80 1e-14
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 80 1e-14
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 80 1e-14
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 79 1e-14
M21616-1|AAA36427.1| 1106|Homo sapiens platelet-derived growth f... 79 1e-14
J03278-1|AAA60049.1| 1106|Homo sapiens platelet-derived growth f... 79 1e-14
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 79 1e-14
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 79 1e-14
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 79 1e-14
BC032224-1|AAH32224.1| 1106|Homo sapiens platelet-derived growth... 79 1e-14
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 79 1e-14
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 79 1e-14
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 79 1e-14
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 79 1e-14
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 79 1e-14
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 79 1e-14
AB209657-1|BAD92894.1| 777|Homo sapiens platelet-derived growth... 79 1e-14
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 79 2e-14
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 79 2e-14
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 79 2e-14
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 79 2e-14
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 78 3e-14
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 78 4e-14
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 78 4e-14
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 78 4e-14
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 78 4e-14
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 78 4e-14
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 78 4e-14
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 78 4e-14
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 78 4e-14
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 78 4e-14
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 78 4e-14
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 78 4e-14
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 78 4e-14
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 77 5e-14
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 77 9e-14
M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth f... 77 9e-14
M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth f... 77 9e-14
D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived gr... 77 9e-14
BC063414-1|AAH63414.1| 743|Homo sapiens PDGFRA protein protein. 77 9e-14
AY229892-1|AAP69563.1| 849|Homo sapiens FIP1L1/PDGFRA fusion pr... 77 9e-14
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 77 9e-14
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 76 2e-13
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 76 2e-13
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 76 2e-13
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 76 2e-13
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 76 2e-13
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 76 2e-13
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 76 2e-13
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 75 2e-13
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 75 2e-13
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 75 2e-13
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 75 2e-13
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 75 2e-13
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 75 2e-13
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 75 2e-13
AL513328-2|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 75 2e-13
AL513328-1|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 75 2e-13
AL157881-3|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 75 2e-13
AL157881-2|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 75 2e-13
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 75 2e-13
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 75 2e-13
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 75 2e-13
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 75 2e-13
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 75 2e-13
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 75 2e-13
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 75 3e-13
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 75 3e-13
BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating fact... 74 7e-13
X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for ... 73 9e-13
U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein. 73 9e-13
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 73 1e-12
AC068970-1|AAX88856.1| 136|Homo sapiens unknown protein. 73 1e-12
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 72 2e-12
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 72 2e-12
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 72 2e-12
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 72 2e-12
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 72 2e-12
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 72 2e-12
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 72 2e-12
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 72 2e-12
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 72 2e-12
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 72 2e-12
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 72 2e-12
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 72 2e-12
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 72 2e-12
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 72 2e-12
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 72 2e-12
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 72 2e-12
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 72 2e-12
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 72 2e-12
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 72 2e-12
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 72 2e-12
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 72 2e-12
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 72 2e-12
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 72 2e-12
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 72 2e-12
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 72 2e-12
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 72 3e-12
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 72 3e-12
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 72 3e-12
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 72 3e-12
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 72 3e-12
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 72 3e-12
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 72 3e-12
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 71 4e-12
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 71 4e-12
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 71 4e-12
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 71 4e-12
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 71 4e-12
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 71 4e-12
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 71 4e-12
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 71 4e-12
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 71 5e-12
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 71 5e-12
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 71 5e-12
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 71 5e-12
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 71 5e-12
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 71 5e-12
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 71 5e-12
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 71 5e-12
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 71 5e-12
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 71 5e-12
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 71 5e-12
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 71 5e-12
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 71 5e-12
AY065844-1|AAL40893.1| 106|Homo sapiens truncated receptor tyro... 71 5e-12
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 71 5e-12
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 71 5e-12
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 71 5e-12
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 71 5e-12
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 71 5e-12
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 71 5e-12
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 71 5e-12
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 71 5e-12
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 71 5e-12
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 71 5e-12
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 71 5e-12
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 71 5e-12
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 71 5e-12
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 71 5e-12
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 71 6e-12
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 71 6e-12
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 71 6e-12
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 71 6e-12
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 71 6e-12
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 71 6e-12
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 71 6e-12
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 71 6e-12
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 71 6e-12
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 71 6e-12
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 71 6e-12
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 71 6e-12
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 71 6e-12
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 71 6e-12
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 71 6e-12
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 71 6e-12
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 71 6e-12
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 71 6e-12
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 71 6e-12
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 71 6e-12
AK131568-1|BAD18701.1| 435|Homo sapiens protein ( Homo sapiens ... 71 6e-12
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 71 6e-12
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 71 6e-12
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 71 6e-12
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 70 8e-12
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 70 8e-12
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 70 8e-12
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 70 8e-12
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 70 8e-12
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 70 1e-11
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 70 1e-11
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 70 1e-11
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 70 1e-11
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 70 1e-11
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 70 1e-11
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 70 1e-11
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 70 1e-11
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 70 1e-11
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 69 1e-11
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 69 1e-11
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 69 1e-11
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 69 1e-11
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 69 1e-11
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 69 1e-11
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 69 1e-11
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 69 1e-11
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 69 1e-11
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 69 1e-11
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 69 1e-11
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 69 1e-11
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 69 1e-11
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 69 1e-11
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 69 2e-11
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 69 2e-11
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 69 2e-11
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 69 2e-11
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 69 2e-11
M29930-1|AAA59177.1| 192|Homo sapiens protein ( Human insulin r... 69 2e-11
M29929-1|AAA59176.1| 192|Homo sapiens protein ( Human insulin r... 69 2e-11
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 69 2e-11
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 69 2e-11
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 69 2e-11
DQ311690-1|ABC55362.1| 81|Homo sapiens insulin receptor protein. 69 2e-11
DQ311687-1|ABC55359.1| 81|Homo sapiens insulin receptor protein. 69 2e-11
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 69 2e-11
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 69 2e-11
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 69 2e-11
AM051278-1|CAJ19684.1| 197|Homo sapiens dominant-negative kinas... 69 2e-11
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 69 2e-11
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 69 2e-11
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 69 2e-11
AB067470-1|BAB67776.1| 1480|Homo sapiens KIAA1883 protein protein. 69 2e-11
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 69 3e-11
X69878-1|CAA49505.1| 1298|Homo sapiens protein ( H.sapiens Flt4 ... 69 3e-11
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 69 3e-11
AY233383-1|AAO89505.1| 1363|Homo sapiens VEGFR3 long form protein. 69 3e-11
AY233382-1|AAO89504.1| 1298|Homo sapiens VEGFR3 short form protein. 69 3e-11
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 69 3e-11
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 69 3e-11
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 68 3e-11
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 68 3e-11
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 68 3e-11
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 68 3e-11
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 68 3e-11
BX538196-1|CAD98063.1| 109|Homo sapiens hypothetical protein pr... 68 3e-11
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 68 3e-11
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 68 3e-11
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 68 3e-11
X68203-1|CAA48290.1| 1304|Homo sapiens FTL4 protein. 68 4e-11
U43143-1|AAA85215.1| 1298|Homo sapiens Flt4 protein. 68 4e-11
DQ311689-1|ABC55361.1| 81|Homo sapiens insulin receptor protein. 68 4e-11
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 68 4e-11
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 68 4e-11
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 68 4e-11
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 68 4e-11
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 67 6e-11
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 67 6e-11
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 67 6e-11
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 67 6e-11
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 67 6e-11
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 67 6e-11
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 67 6e-11
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 67 6e-11
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 67 6e-11
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 67 6e-11
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 67 6e-11
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 67 6e-11
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 67 6e-11
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 67 6e-11
AB209441-1|BAD92678.1| 879|Homo sapiens fibroblast growth facto... 67 6e-11
X69301-1|CAA49159.1| 976|Homo sapiens mast/stem cell growth fa... 67 8e-11
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 67 8e-11
X06182-1|CAA29548.1| 976|Homo sapiens protein ( Human c-kit pro... 67 8e-11
U63834-2|AAC50969.1| 972|Homo sapiens KIT protein protein. 67 8e-11
U63834-1|AAC50968.1| 976|Homo sapiens KIT protein protein. 67 8e-11
DQ836395-1|ABI53804.1| 556|Homo sapiens N2idVEGFR-1 protein. 67 8e-11
DQ836394-1|ABI53803.1| 556|Homo sapiens idVEGFR-1 protein. 67 8e-11
BC071593-1|AAH71593.1| 976|Homo sapiens KIT protein protein. 67 8e-11
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 67 8e-11
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 67 8e-11
AJ438313-1|CAD27356.1| 160|Homo sapiens KIT protein protein. 67 8e-11
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 67 8e-11
AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine ki... 67 8e-11
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 66 1e-10
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 66 1e-10
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 66 1e-10
U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein. 66 1e-10
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 66 1e-10
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 66 1e-10
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 66 1e-10
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 66 1e-10
AY764156-1|AAV37179.1| 334|Homo sapiens NIN/PDGFRB fusion prote... 66 1e-10
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 66 1e-10
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 66 1e-10
AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 66 1e-10
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 66 1e-10
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 66 2e-10
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 66 2e-10
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 66 2e-10
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 66 2e-10
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 66 2e-10
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 66 2e-10
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 66 2e-10
AK131529-1|BAD18667.1| 879|Homo sapiens protein ( Homo sapiens ... 66 2e-10
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 66 2e-10
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 66 2e-10
AB014541-1|BAA31616.2| 1326|Homo sapiens KIAA0641 protein protein. 66 2e-10
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 65 2e-10
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 65 2e-10
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 65 2e-10
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 65 2e-10
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 65 2e-10
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 65 2e-10
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 65 2e-10
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 65 2e-10
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 65 2e-10
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 65 2e-10
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 65 2e-10
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 65 2e-10
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 65 2e-10
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 65 2e-10
AL662870-8|CAM25687.1| 493|Homo sapiens discoidin domain recept... 65 2e-10
AL662870-7|CAI18441.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
AL662870-6|CAI18442.1| 913|Homo sapiens discoidin domain recept... 65 2e-10
AL662854-8|CAM24838.1| 493|Homo sapiens discoidin domain recept... 65 2e-10
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 65 2e-10
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 65 2e-10
AK130776-1|BAC85426.1| 441|Homo sapiens protein ( Homo sapiens ... 65 2e-10
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 65 2e-10
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 65 2e-10
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 65 2e-10
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 65 2e-10
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 65 3e-10
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 65 3e-10
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 65 3e-10
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 64 4e-10
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 64 4e-10
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 64 4e-10
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 64 5e-10
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 64 7e-10
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 63 9e-10
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 63 9e-10
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 63 9e-10
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 63 9e-10
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 63 9e-10
AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein. 63 9e-10
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 63 1e-09
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 63 1e-09
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 63 1e-09
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 63 1e-09
D83492-1|BAA21560.1| 1006|Homo sapiens Eph-family protein protein. 62 2e-09
BC110607-1|AAI10608.2| 1006|Homo sapiens EPH receptor B6 protein. 62 2e-09
BC110606-1|AAI10607.1| 729|Homo sapiens EPHB6 protein protein. 62 2e-09
AY280502-1|AAP20939.1| 1006|Homo sapiens EPHB6 protein. 62 2e-09
AL157881-1|CAH69976.1| 189|Homo sapiens muscle, skeletal, recep... 62 2e-09
AF107256-1|AAD03058.1| 804|Homo sapiens Eph-family protein prot... 62 2e-09
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 62 2e-09
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 62 2e-09
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 62 2e-09
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 62 2e-09
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 62 2e-09
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 62 2e-09
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 62 2e-09
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 62 2e-09
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 62 2e-09
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 62 2e-09
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 62 2e-09
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 62 2e-09
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 62 2e-09
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 62 2e-09
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 62 2e-09
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 62 2e-09
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 62 2e-09
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 61 4e-09
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 40 7e-09
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 60 7e-09
AL121991-2|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 60 7e-09
BC112933-1|AAI12934.1| 387|Homo sapiens EPHA10 protein protein. 60 9e-09
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 60 9e-09
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 60 9e-09
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 60 1e-08
X59292-1|CAA41981.1| 61|Homo sapiens elk-related kinase protein. 58 3e-08
L08961-1|AAC41766.1| 600|Homo sapiens tyrosine kinase protein. 58 4e-08
AY130988-1|AAN08717.1| 1503|Homo sapiens KPI-2 protein protein. 58 4e-08
AC073101-1|AAS07515.1| 263|Homo sapiens unknown protein. 58 4e-08
AB029002-1|BAA83031.2| 1476|Homo sapiens KIAA1079 protein protein. 58 4e-08
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 58 5e-08
U43408-1|AAC50427.1| 666|Homo sapiens tyrosine kinase protein. 58 5e-08
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 58 5e-08
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 58 5e-08
S59184-1|AAB26341.1| 606|Homo sapiens RYK protein. 58 5e-08
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 58 5e-08
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 58 5e-08
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 58 5e-08
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 58 5e-08
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 58 5e-08
AC004416-1|AAF66137.2| 583|Homo sapiens unknown protein. 58 5e-08
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 58 5e-08
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 57 6e-08
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 57 6e-08
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, t... 57 6e-08
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 57 8e-08
X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein. 57 8e-08
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 57 8e-08
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 57 8e-08
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 57 8e-08
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 57 8e-08
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 57 8e-08
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 57 8e-08
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 57 8e-08
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 1877 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 1932
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 1933 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 1992
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 1993 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 2052
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 2053 LCVDISKGCVYLERMHF 2069
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 2059 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 2106
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 1883 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 1938
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 1939 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 1998
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 1999 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 2058
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 2059 LCVDISKGCVYLERMHF 2075
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 2065 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 2112
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 1883 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 1938
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 1939 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 1998
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 1999 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 2058
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 2059 LCVDISKGCVYLERMHF 2075
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 2065 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 2112
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 30 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 85
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 86 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 145
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 146 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 205
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 206 LCVDISKGCVYLERMHF 222
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 212 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 259
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 94 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 149
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 150 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 209
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 210 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 269
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 270 LCVDISKGCVYLERMHF 286
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 276 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 323
>AL132671-5|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 1877 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 1932
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 1933 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 1992
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 1993 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 2052
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 2053 LCVDISKGCVYLERMHF 2069
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 2059 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 2106
>AL132671-4|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 165 bits (401), Expect = 2e-40
Identities = 96/197 (48%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +3
Query: 84 NRNKKKTAIANQNQTVTLRRGPDVELATLRHELPIRHSTNILYNQGVHC-PTDAELASLP 260
+R K A + TV + D ELA LR N Y +H PT E+ +LP
Sbjct: 1883 HRRLKNQKSAKEGVTVLINE--DKELAELRGLAAGVGLANACY--AIHTLPTQEEIENLP 1938
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQING-STVDTKVAVKTLRKGASEQEKTEFLKEA 437
RE++TL LGSGAFGEV+EG A I G + + KVAVKTL+KG+++QEK EFLKEA
Sbjct: 1939 AFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEA 1998
Query: 438 ALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXN 617
LMS F H +IL+ LGVCL N+P YII+ELMEGGDLL+YLR R +
Sbjct: 1999 HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD 2058
Query: 618 MCVDVTKGCRYLERDAF 668
+CVD++KGC YLER F
Sbjct: 2059 LCVDISKGCVYLERMHF 2075
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHR-ANGEGSQELGDFGLARDIYQN 777
K V + MHF+HRDLA RNCLV+ + ++GDFGLARDIY+N
Sbjct: 2065 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 2112
>U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinase
receptor protein.
Length = 1620
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 1103 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 1162
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 1163 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 1222
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 1223 MLDLLHVARDIACGCQYLEENHF 1245
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 1241 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 1279
>U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinase
protein.
Length = 1620
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 1103 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 1162
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 1163 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 1222
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 1223 MLDLLHVARDIACGCQYLEENHF 1245
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 1241 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 1279
>U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic
lymphoma kinase fusion protein protein.
Length = 680
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 163 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 222
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 223 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 282
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 283 MLDLLHVARDIACGCQYLEENHF 305
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 301 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 339
>D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein.
Length = 680
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 163 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 222
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 223 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 282
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 283 MLDLLHVARDIACGCQYLEENHF 305
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 301 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 339
>AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplastic
large cell lymphoma kinase extra long form protein.
Length = 803
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 286 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 345
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 346 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 405
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 406 MLDLLHVARDIACGCQYLEENHF 428
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 424 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 462
>AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplastic
lymphoma kinase (Ki-1) fusion protein long form protein.
Length = 756
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 239 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 298
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 299 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 358
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 359 MLDLLHVARDIACGCQYLEENHF 381
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 377 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 415
>AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplastic
lymphoma kinase fusion protein protein.
Length = 701
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 184 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 243
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 244 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 303
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 304 MLDLLHVARDIACGCQYLEENHF 326
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 322 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 360
>AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein.
Length = 1192
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 675 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 734
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 735 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 794
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 795 MLDLLHVARDIACGCQYLEENHF 817
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 813 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 851
>AB275889-1|BAF73612.1| 1310|Homo sapiens EML4-ALK variant 2 protein.
Length = 1310
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 793 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 852
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 853 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 912
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 913 MLDLLHVARDIACGCQYLEENHF 935
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 931 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 969
>AB274722-1|BAF73611.1| 1059|Homo sapiens EML4-ALK variant 1
protein.
Length = 1059
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 542 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 601
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 602 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 661
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 662 MLDLLHVARDIACGCQYLEENHF 684
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 680 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 718
>AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kinase
Ki-1 variant protein.
Length = 1626
Score = 110 bits (265), Expect = 5e-24
Identities = 56/143 (39%), Positives = 85/143 (59%)
Frame = +3
Query: 240 AELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKT 419
+ ++ L + R+ ITL + LG GAFGEV+EG + +VAVKTL + SEQ++
Sbjct: 1109 SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDEL 1168
Query: 420 EFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXX 599
+FL EA ++S F H++I+R +GV L + P +I++ELM GGDL S+LR R
Sbjct: 1169 DFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLA 1228
Query: 600 XXXXXNMCVDVTKGCRYLERDAF 668
++ D+ GC+YLE + F
Sbjct: 1229 MLDLLHVARDIACGCQYLEENHF 1251
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ G + ++GDFG+ARDIY+
Sbjct: 1247 EENHFIHRDIAARNCLLTCPGPGRVA-KIGDFGMARDIYR 1285
>X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein.
Length = 803
Score = 107 bits (258), Expect = 3e-23
Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 2/176 (1%)
Frame = +3
Query: 147 PDVELATLRHELPIRHSTNILYNQ-GVHCPTDAELA-SLPHIRREQITLSKFLGSGAFGE 320
P++EL+ LR IR + N Y Q G+ L + + +TL + LG GAFGE
Sbjct: 404 PELELSKLRTSA-IRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGE 462
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V+EG+ + G + +VA+KTL + S Q++ +FL EA ++S F+H++I+R +G+ L
Sbjct: 463 VYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRA 522
Query: 501 DPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLERDAF 668
P I++ELM GGD+ S+LR R + D+ +GC YLE + F
Sbjct: 523 TPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHF 578
Score = 48.8 bits (111), Expect = 2e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL++ A ++GDFG+ARDIY+
Sbjct: 574 EENHFIHRDIAARNCLLS-CAGPSRVAKIGDFGMARDIYR 612
>X52213-1|CAA36460.1| 464|Homo sapiens ltk protein.
Length = 464
Score = 107 bits (258), Expect = 3e-23
Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 2/176 (1%)
Frame = +3
Query: 147 PDVELATLRHELPIRHSTNILYNQ-GVHCPTDAELA-SLPHIRREQITLSKFLGSGAFGE 320
P++EL+ LR IR + N Y Q G+ L + + +TL + LG GAFGE
Sbjct: 66 PELELSKLRTSA-IRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGE 124
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V+EG+ + G + +VA+KTL + S Q++ +FL EA ++S F+H++I+R +G+ L
Sbjct: 125 VYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRA 184
Query: 501 DPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLERDAF 668
P I++ELM GGD+ S+LR R + D+ +GC YLE + F
Sbjct: 185 TPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHF 240
Score = 47.2 bits (107), Expect = 7e-05
Identities = 20/40 (50%), Positives = 29/40 (72%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL+ + ++GDFG+ARDIY+
Sbjct: 236 EENHFIHRDIAARNCLLMRGPSRVA--KIGDFGMARDIYR 273
>D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase
protein.
Length = 864
Score = 107 bits (258), Expect = 3e-23
Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 2/176 (1%)
Frame = +3
Query: 147 PDVELATLRHELPIRHSTNILYNQ-GVHCPTDAELA-SLPHIRREQITLSKFLGSGAFGE 320
P++EL+ LR IR + N Y Q G+ L + + +TL + LG GAFGE
Sbjct: 465 PELELSKLRTSA-IRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGE 523
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V+EG+ + G + +VA+KTL + S Q++ +FL EA ++S F+H++I+R +G+ L
Sbjct: 524 VYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRA 583
Query: 501 DPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLERDAF 668
P I++ELM GGD+ S+LR R + D+ +GC YLE + F
Sbjct: 584 TPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHF 639
Score = 48.8 bits (111), Expect = 2e-05
Identities = 21/40 (52%), Positives = 30/40 (75%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
+E HF+HRD+A RNCL++ A ++GDFG+ARDIY+
Sbjct: 635 EENHFIHRDIAARNCLLS-CAGPSRVAKIGDFGMARDIYR 673
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 105 bits (253), Expect = 1e-22
Identities = 50/102 (49%), Positives = 71/102 (69%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+IT+S+ LG G+FG V+EGVA+ + +T+VA+KT+ + AS +E+ EFL EA++
Sbjct: 994 VAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASV 1053
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H++RLLGV P +IMELM GDL SYLR+ R
Sbjct: 1054 MKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLR 1095
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 27/36 (75%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VA + + ++GDFG+ RDIY+
Sbjct: 1131 FVHRDLAARNCMVAE----DFTVKIGDFGMTRDIYE 1162
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 105 bits (253), Expect = 1e-22
Identities = 50/102 (49%), Positives = 71/102 (69%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+IT+S+ LG G+FG V+EGVA+ + +T+VA+KT+ + AS +E+ EFL EA++
Sbjct: 994 VAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASV 1053
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H++RLLGV P +IMELM GDL SYLR+ R
Sbjct: 1054 MKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLR 1095
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 27/36 (75%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VA + + ++GDFG+ RDIY+
Sbjct: 1131 FVHRDLAARNCMVAE----DFTVKIGDFGMTRDIYE 1162
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 105 bits (253), Expect = 1e-22
Identities = 50/102 (49%), Positives = 71/102 (69%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+IT+S+ LG G+FG V+EGVA+ + +T+VA+KT+ + AS +E+ EFL EA++
Sbjct: 994 VAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASV 1053
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H++RLLGV P +IMELM GDL SYLR+ R
Sbjct: 1054 MKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLR 1095
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 27/36 (75%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VA + + ++GDFG+ RDIY+
Sbjct: 1131 FVHRDLAARNCMVAE----DFTVKIGDFGMTRDIYE 1162
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 105 bits (253), Expect = 1e-22
Identities = 50/102 (49%), Positives = 71/102 (69%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+IT+S+ LG G+FG V+EGVA+ + +T+VA+KT+ + AS +E+ EFL EA++
Sbjct: 994 VAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASV 1053
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H++RLLGV P +IMELM GDL SYLR+ R
Sbjct: 1054 MKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLR 1095
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 27/36 (75%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VA + + ++GDFG+ RDIY+
Sbjct: 1131 FVHRDLAARNCMVAE----DFTVKIGDFGMTRDIYE 1162
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 103 bits (248), Expect = 5e-22
Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+ITL + LG G+FG V+EG AR I +T+VAVKT+ + AS +E+ EFL EA++
Sbjct: 1006 VSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASV 1065
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR---EFXXXXXXXXXXXXX 614
M F H++RLLGV P ++MELM GDL SYLR+ R E
Sbjct: 1066 MKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMI 1125
Query: 615 NMCVDVTKGCRYLERDAF 668
M ++ G YL F
Sbjct: 1126 QMAAEIADGMAYLNAKKF 1143
Score = 48.0 bits (109), Expect = 4e-05
Identities = 21/36 (58%), Positives = 28/36 (77%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VAH + + ++GDFG+ RDIY+
Sbjct: 1143 FVHRDLAARNCMVAH----DFTVKIGDFGMTRDIYE 1174
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 103 bits (248), Expect = 5e-22
Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+ITL + LG G+FG V+EG AR I +T+VAVKT+ + AS +E+ EFL EA++
Sbjct: 1018 VSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASV 1077
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR---EFXXXXXXXXXXXXX 614
M F H++RLLGV P ++MELM GDL SYLR+ R E
Sbjct: 1078 MKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMI 1137
Query: 615 NMCVDVTKGCRYLERDAF 668
M ++ G YL F
Sbjct: 1138 QMAAEIADGMAYLNAKKF 1155
Score = 48.0 bits (109), Expect = 4e-05
Identities = 21/36 (58%), Positives = 28/36 (77%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VAH + + ++GDFG+ RDIY+
Sbjct: 1155 FVHRDLAARNCMVAH----DFTVKIGDFGMTRDIYE 1186
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 103 bits (248), Expect = 5e-22
Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+ITL + LG G+FG V+EG AR I +T+VAVKT+ + AS +E+ EFL EA++
Sbjct: 1018 VSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASV 1077
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR---EFXXXXXXXXXXXXX 614
M F H++RLLGV P ++MELM GDL SYLR+ R E
Sbjct: 1078 MKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMI 1137
Query: 615 NMCVDVTKGCRYLERDAF 668
M ++ G YL F
Sbjct: 1138 QMAAEIADGMAYLNAKKF 1155
Score = 48.0 bits (109), Expect = 4e-05
Identities = 21/36 (58%), Positives = 28/36 (77%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VAH + + ++GDFG+ RDIY+
Sbjct: 1155 FVHRDLAARNCMVAH----DFTVKIGDFGMTRDIYE 1186
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 103 bits (248), Expect = 5e-22
Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+ITL + LG G+FG V+EG AR I +T+VAVKT+ + AS +E+ EFL EA++
Sbjct: 1006 VSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASV 1065
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR---EFXXXXXXXXXXXXX 614
M F H++RLLGV P ++MELM GDL SYLR+ R E
Sbjct: 1066 MKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMI 1125
Query: 615 NMCVDVTKGCRYLERDAF 668
M ++ G YL F
Sbjct: 1126 QMAAEIADGMAYLNAKKF 1143
Score = 48.0 bits (109), Expect = 4e-05
Identities = 21/36 (58%), Positives = 28/36 (77%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VAH + + ++GDFG+ RDIY+
Sbjct: 1143 FVHRDLAARNCMVAH----DFTVKIGDFGMTRDIYE 1174
>AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor variant
protein.
Length = 833
Score = 103 bits (248), Expect = 5e-22
Identities = 57/138 (41%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+ITL + LG G+FG V+EG AR I +T+VAVKT+ + AS +E+ EFL EA++
Sbjct: 469 VSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASV 528
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR---EFXXXXXXXXXXXXX 614
M F H++RLLGV P ++MELM GDL SYLR+ R E
Sbjct: 529 MKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMI 588
Query: 615 NMCVDVTKGCRYLERDAF 668
M ++ G YL F
Sbjct: 589 QMAAEIADGMAYLNAKKF 606
Score = 48.0 bits (109), Expect = 4e-05
Identities = 21/36 (58%), Positives = 28/36 (77%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+VAH + + ++GDFG+ RDIY+
Sbjct: 606 FVHRDLAARNCMVAH----DFTVKIGDFGMTRDIYE 637
>M27197-1|AAA86791.1| 118|Homo sapiens INSR protein.
Length = 118
Score = 103 bits (247), Expect = 7e-22
Identities = 51/102 (50%), Positives = 69/102 (67%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ RE+ITL + LG G+FG V+EG AR I +T+VAVKT+ + AS +E+ EFL EA++
Sbjct: 13 VSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASV 72
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H++RLLGV P ++MELM GDL SYLR+ R
Sbjct: 73 MKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLR 114
>J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related
receptor protein.
Length = 1268
Score = 99 bits (238), Expect = 9e-21
Identities = 50/102 (49%), Positives = 69/102 (67%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ REQI++ + LG G+FG V+EG+AR + T VA+KT+ + AS +E EFLKEA++
Sbjct: 945 VPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASV 1004
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M FK H++RLLGV P +IMELM GDL S+LR+ R
Sbjct: 1005 MKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLR 1046
Score = 43.2 bits (97), Expect = 0.001
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+V+ + + ++GDFG+ RD+Y+
Sbjct: 1082 FVHRDLAARNCMVSQ----DFTVKIGDFGMTRDVYE 1113
>AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-related
receptor protein.
Length = 1297
Score = 99 bits (238), Expect = 9e-21
Identities = 50/102 (49%), Positives = 69/102 (67%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ REQI++ + LG G+FG V+EG+AR + T VA+KT+ + AS +E EFLKEA++
Sbjct: 974 VPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASV 1033
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M FK H++RLLGV P +IMELM GDL S+LR+ R
Sbjct: 1034 MKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLR 1075
Score = 43.2 bits (97), Expect = 0.001
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQ 774
FVHRDLA RNC+V+ + + ++GDFG+ RD+Y+
Sbjct: 1111 FVHRDLAARNCMVSQ----DFTVKIGDFGMTRDVYE 1142
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 88.6 bits (210), Expect = 2e-17
Identities = 41/103 (39%), Positives = 65/103 (63%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + LG G FGEV++G + T VAVKT ++ ++ K +FL+EA +
Sbjct: 558 LSHEDVILGELLGKGNFGEVYKGTLKD------KTSVAVKTCKEDLPQELKIKFLQEAKI 611
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ + H +I++L+GVC P YIIMEL+ GGD L++LR K++
Sbjct: 612 LKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKD 654
Score = 31.1 bits (67), Expect = 4.7
Identities = 16/32 (50%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
+HRDLA RNCLV GE + ++ DFG++R
Sbjct: 681 IHRDLAARNCLV-----GENNVLKISDFGMSR 707
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 532 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 590
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 671 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 702
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 532 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 590
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 671 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 702
>AL596132-4|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 548 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 606
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 647
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 687 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 718
>AL596132-3|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 532 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 590
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 671 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 702
>AL445532-2|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 548 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 606
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 647
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 687 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 718
>AL445532-1|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 532 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 590
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 671 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 702
>AL390777-4|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 548 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 606
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 647
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 687 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 718
>AL390777-3|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 532 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 590
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 671 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 702
>AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor
tyrosine kinase type 2 protein.
Length = 838
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 548 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 606
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 647
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 687 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 718
>AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine
kinase receptor type 2 protein.
Length = 822
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 532 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 590
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 671 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 702
>AB209118-1|BAD92355.1| 781|Homo sapiens BDNF/NT-3 growth factors
receptor precursor variant protein.
Length = 781
Score = 87.8 bits (208), Expect = 4e-17
Identities = 44/101 (43%), Positives = 63/101 (62%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
HI+R I L + LG GAFG+VF + VAVKTL K AS+ + +F +EA
Sbjct: 578 HIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAE 636
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
L++N +HEHI++ GVC++ DP ++ E M+ GDL +LRA
Sbjct: 637 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA 677
Score = 44.8 bits (101), Expect = 4e-04
Identities = 20/36 (55%), Positives = 25/36 (69%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
HFVHRDLA RNCLV ++GDFG++RD+Y
Sbjct: 717 HFVHRDLATRNCLVGENL----LVKIGDFGMSRDVY 748
>U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta
protein.
Length = 1009
Score = 85.8 bits (203), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 420 IAREDVVLNRILGEGLFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 477
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 478 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 518
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 535 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 574
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + +G G FGEVF G R N T VAVK+ R+ K +FL+EA +
Sbjct: 556 LNHEDLVLGEQIGRGNFGEVFSGRLRADN-----TLVAVKSCRETLPPDLKAKFLQEARI 610
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
+ + H +I+RL+GVC P YI+MEL++GGD L++LR +
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE 651
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARD 765
+HRDLA RNCLV + ++ DFG++R+
Sbjct: 680 IHRDLAARNCLVTEK----NVLKISDFGMSRE 707
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + +G G FGEVF G R N T VAVK+ R+ K +FL+EA +
Sbjct: 556 LNHEDLVLGEQIGRGNFGEVFSGRLRADN-----TLVAVKSCRETLPPDLKAKFLQEARI 610
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
+ + H +I+RL+GVC P YI+MEL++GGD L++LR +
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE 651
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARD 765
+HRDLA RNCLV + ++ DFG++R+
Sbjct: 680 IHRDLAARNCLVTEK----NVLKISDFGMSRE 707
>U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein.
Length = 1009
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 477
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 478 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 518
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 535 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 574
>S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal
tyrosine kinase protein.
Length = 1009
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 477
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 478 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 518
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 535 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 574
>L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase
protein.
Length = 1009
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 477
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 478 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 518
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 535 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 574
>BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 477
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 478 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 518
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 535 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 574
>BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 477
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 478 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 518
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 535 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 574
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + +G G FGEVF G R N T VAVK+ R+ K +FL+EA +
Sbjct: 556 LNHEDLVLGEQIGRGNFGEVFSGRLRADN-----TLVAVKSCRETLPPDLKAKFLQEARI 610
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
+ + H +I+RL+GVC P YI+MEL++GGD L++LR +
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE 651
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARD 765
+HRDLA RNCLV + ++ DFG++R+
Sbjct: 680 IHRDLAARNCLVTEK----NVLKISDFGMSRE 707
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes
variant 4 protein.
Length = 752
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + +G G FGEVF G R N T VAVK+ R+ K +FL+EA +
Sbjct: 486 LNHEDLVLGEQIGRGNFGEVFSGRLRADN-----TLVAVKSCRETLPPDLKAKFLQEARI 540
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
+ + H +I+RL+GVC P YI+MEL++GGD L++LR +
Sbjct: 541 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE 581
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARD 765
+HRDLA RNCLV + ++ DFG++R+
Sbjct: 610 IHRDLAARNCLVTEK----NVLKISDFGMSRE 637
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + +G G FGEVF G R N T VAVK+ R+ K +FL+EA +
Sbjct: 498 LNHEDLVLGEQIGRGNFGEVFSGRLRADN-----TLVAVKSCRETLPPDLKAKFLQEARI 552
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
+ + H +I+RL+GVC P YI+MEL++GGD L++LR +
Sbjct: 553 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE 593
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARD 765
+HRDLA RNCLV + ++ DFG++R+
Sbjct: 622 IHRDLAARNCLVTEK----NVLKISDFGMSRE 649
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes
variant 1 protein.
Length = 694
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ E + L + +G G FGEVF G R N T VAVK+ R+ K +FL+EA +
Sbjct: 428 LNHEDLVLGEQIGRGNFGEVFSGRLRADN-----TLVAVKSCRETLPPDLKAKFLQEARI 482
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
+ + H +I+RL+GVC P YI+MEL++GGD L++LR +
Sbjct: 483 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE 523
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARD 765
+HRDLA RNCLV + ++ DFG++R+
Sbjct: 552 IHRDLAARNCLVTEK----NVLKISDFGMSRE 579
>AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens
cDNA FLJ46514 fis, clone THYMU3032798, highly similar
to Focal adhesion kinase 2 (EC 2.7.1.112). ).
Length = 596
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 166 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 223
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 224 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 264
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 281 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 320
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 85.4 bits (202), Expect = 2e-16
Identities = 44/113 (38%), Positives = 64/113 (56%)
Frame = +3
Query: 225 HCPTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGAS 404
H +A + HI+R I L + LG GAFG+VF ++ + VAVK L+
Sbjct: 13 HAMPIGRIADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL 72
Query: 405 EQEKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
K +F +EA L++N +HEHI++ GVC D DP ++ E M+ GDL +LRA
Sbjct: 73 AARK-DFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRA 124
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/50 (50%), Positives = 31/50 (62%)
Frame = +1
Query: 622 AST*QKAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
AS +V HFVHRDLA RNCLV AN ++GDFG++RD+Y
Sbjct: 153 ASQIASGMVYLASQHFVHRDLATRNCLVG--AN--LLVKIGDFGMSRDVY 198
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 85.4 bits (202), Expect = 2e-16
Identities = 44/113 (38%), Positives = 64/113 (56%)
Frame = +3
Query: 225 HCPTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGAS 404
H +A + HI+R I L + LG GAFG+VF ++ + VAVK L+
Sbjct: 103 HAMPIGRIADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL 162
Query: 405 EQEKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
K +F +EA L++N +HEHI++ GVC D DP ++ E M+ GDL +LRA
Sbjct: 163 AARK-DFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRA 214
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/50 (50%), Positives = 31/50 (62%)
Frame = +1
Query: 622 AST*QKAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
AS +V HFVHRDLA RNCLV AN ++GDFG++RD+Y
Sbjct: 243 ASQIASGMVYLASQHFVHRDLATRNCLVG--AN--LLVKIGDFGMSRDVY 288
>AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine
kinase 2 beta isoform a variant protein.
Length = 802
Score = 85.4 bits (202), Expect = 2e-16
Identities = 42/102 (41%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE + L++ LG G FGEV+EGV G ++ VAVKT +K + K +F+ EA +
Sbjct: 425 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKIN--VAVKTCKKDCTLDNKEKFMSEAVI 482
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M N H HI++L+G+ ++ +P +IIMEL G+L YL +
Sbjct: 483 MKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK 523
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
KA+ + ++ VHRD+A RN LVA +LGDFGL+R I
Sbjct: 540 KAMAYLESINCVHRDIAVRNILVA----SPECVKLGDFGLSRYI 579
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 84.2 bits (199), Expect = 5e-16
Identities = 44/112 (39%), Positives = 64/112 (57%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
P A L I +T K +G+G FGEV++G+ + +G + VA+KTL+ G +E+
Sbjct: 597 PNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKK-EVPVAIKTLKAGYTEK 655
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
++ +FL EA +M F H +I+RL GV P II E ME G L +LR K
Sbjct: 656 QRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREK 707
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 733 MNYVHRDLAARNILV----NSNLVCKVSDFGLSR 762
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 84.2 bits (199), Expect = 5e-16
Identities = 44/112 (39%), Positives = 64/112 (57%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
P A L I +T K +G+G FGEV++G+ + +G + VA+KTL+ G +E+
Sbjct: 597 PNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKK-EVPVAIKTLKAGYTEK 655
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
++ +FL EA +M F H +I+RL GV P II E ME G L +LR K
Sbjct: 656 QRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREK 707
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 733 MNYVHRDLAARNILV----NSNLVCKVSDFGLSR 762
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 84.2 bits (199), Expect = 5e-16
Identities = 44/112 (39%), Positives = 64/112 (57%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
P A L I +T K +G+G FGEV++G+ + +G + VA+KTL+ G +E+
Sbjct: 597 PNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKK-EVPVAIKTLKAGYTEK 655
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAK 566
++ +FL EA +M F H +I+RL GV P II E ME G L +LR K
Sbjct: 656 QRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREK 707
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 733 MNYVHRDLAARNILV----NSNLVCKVSDFGLSR 762
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 289
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 290 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 328
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 355 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 386
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 289
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 290 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 328
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 355 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 386
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 308
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 309 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 347
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 374 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 405
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 83.8 bits (198), Expect = 6e-16
Identities = 50/144 (34%), Positives = 76/144 (52%)
Frame = +3
Query: 132 TLRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGA 311
+L GPD + + +P+ + + QG +C HI+R I L + LG GA
Sbjct: 493 SLDAGPDTVVIGMTR-IPVIENPQY-FRQGHNCHKPDTYVQ--HIKRRDIVLKRELGEGA 548
Query: 312 FGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVC 491
FG+VF ++ + VAVK L+ K +F +EA L++N +HEHI++ GVC
Sbjct: 549 FGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQHEHIVKFYGVC 607
Query: 492 LDNDPNYIIMELMEGGDLLSYLRA 563
D DP ++ E M+ GDL +LRA
Sbjct: 608 GDGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/50 (50%), Positives = 31/50 (62%)
Frame = +1
Query: 622 AST*QKAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
AS +V HFVHRDLA RNCLV AN ++GDFG++RD+Y
Sbjct: 660 ASQIASGMVYLASQHFVHRDLATRNCLVG--AN--LLVKIGDFGMSRDVY 705
>S76475-1|AAB33111.1| 839|Homo sapiens trkC protein.
Length = 839
Score = 83.8 bits (198), Expect = 6e-16
Identities = 50/144 (34%), Positives = 76/144 (52%)
Frame = +3
Query: 132 TLRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGA 311
+L GPD + + +P+ + + QG +C HI+R I L + LG GA
Sbjct: 493 SLDAGPDTVVIGMTR-IPVIENPQY-FRQGHNCHKPDTYVQ--HIKRRDIVLKRELGEGA 548
Query: 312 FGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVC 491
FG+VF ++ + VAVK L+ K +F +EA L++N +HEHI++ GVC
Sbjct: 549 FGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQHEHIVKFYGVC 607
Query: 492 LDNDPNYIIMELMEGGDLLSYLRA 563
D DP ++ E M+ GDL +LRA
Sbjct: 608 GDGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/50 (50%), Positives = 31/50 (62%)
Frame = +1
Query: 622 AST*QKAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
AS +V HFVHRDLA RNCLV AN ++GDFG++RD+Y
Sbjct: 660 ASQIASGMVYLASQHFVHRDLATRNCLVG--AN--LLVKIGDFGMSRDVY 705
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 289
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 290 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 328
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 355 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 386
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 308
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 309 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 347
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 374 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 405
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 308
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 309 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 347
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 374 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 405
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 308
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 309 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 347
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 374 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 405
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 308
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 309 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 347
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 374 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 405
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 289
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 290 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 328
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 355 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 386
>AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein.
Length = 839
Score = 83.8 bits (198), Expect = 6e-16
Identities = 50/144 (34%), Positives = 76/144 (52%)
Frame = +3
Query: 132 TLRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGA 311
+L GPD + + +P+ + + QG +C HI+R I L + LG GA
Sbjct: 493 SLDAGPDTVVIGMTR-IPVIENPQY-FRQGHNCHKPDTYVQ--HIKRRDIVLKRELGEGA 548
Query: 312 FGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVC 491
FG+VF ++ + VAVK L+ K +F +EA L++N +HEHI++ GVC
Sbjct: 549 FGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQHEHIVKFYGVC 607
Query: 492 LDNDPNYIIMELMEGGDLLSYLRA 563
D DP ++ E M+ GDL +LRA
Sbjct: 608 GDGDPLIMVFEYMKHGDLNKFLRA 631
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/50 (50%), Positives = 31/50 (62%)
Frame = +1
Query: 622 AST*QKAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
AS +V HFVHRDLA RNCLV AN ++GDFG++RD+Y
Sbjct: 660 ASQIASGMVYLASQHFVHRDLATRNCLVG--AN--LLVKIGDFGMSRDVY 705
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/99 (47%), Positives = 62/99 (62%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 274 MERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 326
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YII E M G+LL YLR
Sbjct: 327 MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR 365
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 392 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 423
>Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine
kinase precursor protein.
Length = 993
Score = 83.4 bits (197), Expect = 8e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
RE + K LGSGAFG+V A I+ + V +VAVK L++ A E+ + E +M+
Sbjct: 607 RENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMT 666
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
HE+I+ LLG C + P Y+I E GDLL+YLR+KRE
Sbjct: 667 QLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRE 708
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/33 (60%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN LV H G+ ++ DFGLARDI
Sbjct: 808 VHRDLAARNVLVTH---GK-VVKICDFGLARDI 836
>U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein
kinase protein.
Length = 993
Score = 83.4 bits (197), Expect = 8e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
RE + K LGSGAFG+V A I+ + V +VAVK L++ A E+ + E +M+
Sbjct: 607 RENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMT 666
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
HE+I+ LLG C + P Y+I E GDLL+YLR+KRE
Sbjct: 667 QLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRE 708
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/33 (60%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN LV H G+ ++ DFGLARDI
Sbjct: 808 VHRDLAARNVLVTH---GK-VVKICDFGLARDI 836
>BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 993
Score = 83.4 bits (197), Expect = 8e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
RE + K LGSGAFG+V A I+ + V +VAVK L++ A E+ + E +M+
Sbjct: 607 RENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMT 666
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
HE+I+ LLG C + P Y+I E GDLL+YLR+KRE
Sbjct: 667 QLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRE 708
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/33 (60%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN LV H G+ ++ DFGLARDI
Sbjct: 808 VHRDLAARNVLVTH---GK-VVKICDFGLARDI 836
>AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 996
Score = 83.4 bits (197), Expect = 8e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
RE + K LGSGAFG+V A I+ + V +VAVK L++ A E+ + E +M+
Sbjct: 607 RENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMT 666
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
HE+I+ LLG C + P Y+I E GDLL+YLR+KRE
Sbjct: 667 QLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRE 708
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/33 (60%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN LV H G+ ++ DFGLARDI
Sbjct: 808 VHRDLAARNVLVTH---GK-VVKICDFGLARDI 836
>AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 996
Score = 83.4 bits (197), Expect = 8e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
RE + K LGSGAFG+V A I+ + V +VAVK L++ A E+ + E +M+
Sbjct: 607 RENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMT 666
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
HE+I+ LLG C + P Y+I E GDLL+YLR+KRE
Sbjct: 667 QLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRE 708
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/33 (60%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN LV H G+ ++ DFGLARDI
Sbjct: 808 VHRDLAARNVLVTH---GK-VVKICDFGLARDI 836
>AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 996
Score = 83.4 bits (197), Expect = 8e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
RE + K LGSGAFG+V A I+ + V +VAVK L++ A E+ + E +M+
Sbjct: 607 RENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMT 666
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
HE+I+ LLG C + P Y+I E GDLL+YLR+KRE
Sbjct: 667 QLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRE 708
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/33 (60%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN LV H G+ ++ DFGLARDI
Sbjct: 808 VHRDLAARNVLVTH---GK-VVKICDFGLARDI 836
>X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA fragment
for epidermal growth factor (EGF) receptor. ).
Length = 800
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 526 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 581
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 582 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 640
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 641 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 687
>X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor
receptor protein.
Length = 1210
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 668 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 723
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 724 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 782
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 783 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 829
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 79.8 bits (188), Expect = 1e-14
Identities = 47/136 (34%), Positives = 71/136 (52%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A L ++ ++ K LGSGAFG V++G+ G TV VA+K L + + EF+
Sbjct: 708 AQLRILKETELKRVKVLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFM 766
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXX 608
EA +M++ H H++RLLGVCL + ++ +LM G LL Y+ ++
Sbjct: 767 DEALIMASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCLLEYVHEHKD------NIGSQL 819
Query: 609 XXNMCVDVTKGCRYLE 656
N CV + KG YLE
Sbjct: 820 LLNWCVQIAKGMMYLE 835
Score = 31.1 bits (67), Expect = 4.7
Identities = 18/42 (42%), Positives = 23/42 (54%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
K ++ +E VHRDLA RN LV ++ DFGLAR
Sbjct: 829 KGMMYLEERRLVHRDLAARNVLV----KSPNHVKITDFGLAR 866
>BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 79.8 bits (188), Expect = 1e-14
Identities = 51/141 (36%), Positives = 73/141 (51%), Gaps = 6/141 (4%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR-KGASEQEKTEFLKEAA 440
I R + L K LG G FG V EG +Q +G+++ KVAVKT++ +S++E EFL EAA
Sbjct: 406 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSL--KVAVKTMKLDNSSQREIEEFLSEAA 463
Query: 441 LMSNFKHEHILRLLGVCLDNDPN-----YIIMELMEGGDLLSYLRAKREFXXXXXXXXXX 605
M +F H +++RLLGVC++ +I+ M+ GDL +YL R
Sbjct: 464 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSR-LETGPKHIPLQ 522
Query: 606 XXXNMCVDVTKGCRYLERDAF 668
VD+ G YL F
Sbjct: 523 TLLKFMVDIALGMEYLSNRNF 543
Score = 32.3 bits (70), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+F+HRDLA RNC++ + + + DFGL++ IY
Sbjct: 542 NFLHRDLAARNCML----RDDMTVCVADFGLSKKIY 573
>BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 79.8 bits (188), Expect = 1e-14
Identities = 51/141 (36%), Positives = 73/141 (51%), Gaps = 6/141 (4%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR-KGASEQEKTEFLKEAA 440
I R + L K LG G FG V EG +Q +G+++ KVAVKT++ +S++E EFL EAA
Sbjct: 406 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSL--KVAVKTMKLDNSSQREIEEFLSEAA 463
Query: 441 LMSNFKHEHILRLLGVCLDNDPN-----YIIMELMEGGDLLSYLRAKREFXXXXXXXXXX 605
M +F H +++RLLGVC++ +I+ M+ GDL +YL R
Sbjct: 464 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSR-LETGPKHIPLQ 522
Query: 606 XXXNMCVDVTKGCRYLERDAF 668
VD+ G YL F
Sbjct: 523 TLLKFMVDIALGMEYLSNRNF 543
Score = 32.3 bits (70), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+F+HRDLA RNC++ + + + DFGL++ IY
Sbjct: 542 NFLHRDLAARNCML----RDDMTVCVADFGLSKKIY 573
>BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 (avian) protein.
Length = 1308
Score = 79.8 bits (188), Expect = 1e-14
Identities = 47/136 (34%), Positives = 71/136 (52%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A L ++ ++ K LGSGAFG V++G+ G TV VA+K L + + EF+
Sbjct: 708 AQLRILKETELKRVKVLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFM 766
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXX 608
EA +M++ H H++RLLGVCL + ++ +LM G LL Y+ ++
Sbjct: 767 DEALIMASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCLLEYVHEHKD------NIGSQL 819
Query: 609 XXNMCVDVTKGCRYLE 656
N CV + KG YLE
Sbjct: 820 LLNWCVQIAKGMMYLE 835
Score = 31.1 bits (67), Expect = 4.7
Identities = 18/42 (42%), Positives = 23/42 (54%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
K ++ +E VHRDLA RN LV ++ DFGLAR
Sbjct: 829 KGMMYLEERRLVHRDLAARNVLV----KSPNHVKITDFGLAR 866
>BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein.
Length = 1091
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 623 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 678
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 679 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 737
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 738 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 784
>AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor
receptor (erythroblastic leukemia viral (v-erb-b) oncog
protein.
Length = 1210
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 668 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 723
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 724 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 782
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 783 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 829
>AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting
protein 40 protein.
Length = 1210
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 668 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 723
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 724 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 782
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 783 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 829
>AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth factor
receptor protein.
Length = 1210
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 668 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 723
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 724 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 782
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 783 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 829
>AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine
kinase protein.
Length = 978
Score = 79.8 bits (188), Expect = 1e-14
Identities = 51/141 (36%), Positives = 73/141 (51%), Gaps = 6/141 (4%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR-KGASEQEKTEFLKEAA 440
I R + L K LG G FG V EG +Q +G+++ KVAVKT++ +S++E EFL EAA
Sbjct: 561 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSL--KVAVKTMKLDNSSQREIEEFLSEAA 618
Query: 441 LMSNFKHEHILRLLGVCLDNDPN-----YIIMELMEGGDLLSYLRAKREFXXXXXXXXXX 605
M +F H +++RLLGVC++ +I+ M+ GDL +YL R
Sbjct: 619 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSR-LETGPKHIPLQ 677
Query: 606 XXXNMCVDVTKGCRYLERDAF 668
VD+ G YL F
Sbjct: 678 TLLKFMVDIALGMEYLSNRNF 698
Score = 32.3 bits (70), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+F+HRDLA RNC++ + + + DFGL++ IY
Sbjct: 697 NFLHRDLAARNCML----RDDMTVCVADFGLSKKIY 728
>AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein.
Length = 567
Score = 79.8 bits (188), Expect = 1e-14
Identities = 51/141 (36%), Positives = 73/141 (51%), Gaps = 6/141 (4%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR-KGASEQEKTEFLKEAA 440
I R + L K LG G FG V EG +Q +G+++ KVAVKT++ +S++E EFL EAA
Sbjct: 150 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSL--KVAVKTMKLDNSSQREIEEFLSEAA 207
Query: 441 LMSNFKHEHILRLLGVCLDNDPN-----YIIMELMEGGDLLSYLRAKREFXXXXXXXXXX 605
M +F H +++RLLGVC++ +I+ M+ GDL +YL R
Sbjct: 208 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSR-LETGPKHIPLQ 266
Query: 606 XXXNMCVDVTKGCRYLERDAF 668
VD+ G YL F
Sbjct: 267 TLLKFMVDIALGMEYLSNRNF 287
Score = 32.3 bits (70), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+F+HRDLA RNC++ + + + DFGL++ IY
Sbjct: 286 NFLHRDLAARNCML----RDDMTVCVADFGLSKKIY 317
>AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 variant protein.
Length = 892
Score = 79.8 bits (188), Expect = 1e-14
Identities = 47/136 (34%), Positives = 71/136 (52%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A L ++ ++ K LGSGAFG V++G+ G TV VA+K L + + EF+
Sbjct: 308 AQLRILKETELKRVKVLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFM 366
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXX 608
EA +M++ H H++RLLGVCL + ++ +LM G LL Y+ ++
Sbjct: 367 DEALIMASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCLLEYVHEHKD------NIGSQL 419
Query: 609 XXNMCVDVTKGCRYLE 656
N CV + KG YLE
Sbjct: 420 LLNWCVQIAKGMMYLE 435
Score = 31.1 bits (67), Expect = 4.7
Identities = 18/42 (42%), Positives = 23/42 (54%)
Frame = +1
Query: 637 KAVVI*KEMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
K ++ +E VHRDLA RN LV ++ DFGLAR
Sbjct: 429 KGMMYLEERRLVHRDLAARNVLV----KSPNHVKITDFGLAR 466
>AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor
receptor isoform a variant protein.
Length = 1081
Score = 79.8 bits (188), Expect = 1e-14
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +3
Query: 135 LRRGPDVELATLRHELPIRHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
+RR V TLR L R L G P A L L ++I K LGSGAF
Sbjct: 539 MRRRHIVRKRTLRRLLQERELVEPLTPSG-EAPNQALLRILKETEFKKI---KVLGSGAF 594
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G V++G+ G V VA+K LR+ S + E L EA +M++ + H+ RLLG+CL
Sbjct: 595 GTVYKGLWIP-EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL 653
Query: 495 DNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVTKGCRYLE 656
+ +I +LM G LL Y+R ++ N CV + KG YLE
Sbjct: 654 TSTVQ-LITQLMPFGCLLDYVREHKD------NIGSQYLLNWCVQIAKGMNYLE 700
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 335
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 336 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 374
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 401 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 432
>M21616-1|AAA36427.1| 1106|Homo sapiens platelet-derived growth
factor receptor protein.
Length = 1106
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/104 (42%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+Q+ L + LGSGAFG+V E A ++ S KVAVK L+ A EK + E +MS
Sbjct: 597 RDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMS 656
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYL-RAKREF 575
+ H +++ LLG C P YII E GDL+ YL R K F
Sbjct: 657 HLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTF 700
Score = 31.9 bits (69), Expect = 2.7
Identities = 19/37 (51%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGS-QELGDFGLARDIYQN 777
VHRDLA RN L+ EG ++ DFGLARDI ++
Sbjct: 823 VHRDLAARNVLIC-----EGKLVKICDFGLARDIMRD 854
>J03278-1|AAA60049.1| 1106|Homo sapiens platelet-derived growth
factor receptor protein.
Length = 1106
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/104 (42%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+Q+ L + LGSGAFG+V E A ++ S KVAVK L+ A EK + E +MS
Sbjct: 597 RDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMS 656
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYL-RAKREF 575
+ H +++ LLG C P YII E GDL+ YL R K F
Sbjct: 657 HLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTF 700
Score = 31.9 bits (69), Expect = 2.7
Identities = 19/37 (51%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGS-QELGDFGLARDIYQN 777
VHRDLA RN L+ EG ++ DFGLARDI ++
Sbjct: 823 VHRDLAARNVLIC-----EGKLVKICDFGLARDIMRD 854
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 335
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 336 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 374
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 401 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 432
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 296 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 348
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 349 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 387
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 414 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 445
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 320
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 321 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 359
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 386 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 417
>BC032224-1|AAH32224.1| 1106|Homo sapiens platelet-derived growth
factor receptor, beta polypeptide protein.
Length = 1106
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/104 (42%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+Q+ L + LGSGAFG+V E A ++ S KVAVK L+ A EK + E +MS
Sbjct: 597 RDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMS 656
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYL-RAKREF 575
+ H +++ LLG C P YII E GDL+ YL R K F
Sbjct: 657 HLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTF 700
Score = 31.9 bits (69), Expect = 2.7
Identities = 19/37 (51%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGS-QELGDFGLARDIYQN 777
VHRDLA RN L+ EG ++ DFGLARDI ++
Sbjct: 823 VHRDLAARNVLIC-----EGKLVKICDFGLARDIMRD 854
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 335
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 336 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 374
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 401 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 432
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 320
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 321 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 359
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 386 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 417
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 335
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 336 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 374
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 401 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 432
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 320
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 321 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 359
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 386 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 417
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 335
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 336 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 374
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 401 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 432
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 79.4 bits (187), Expect = 1e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
+ R IT+ LG G +GEV+ GV ++ + VAVKTL++ E E EFLKEAA+
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAV 320
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M KH ++++LLGVC P YI+ E M G+LL YLR
Sbjct: 321 MKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLR 359
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 386 EKKNFIHRDLAARNCLV-----GENHVVKVADFGLSR 417
>AB209657-1|BAD92894.1| 777|Homo sapiens platelet-derived growth
factor receptor beta precursor variant protein.
Length = 777
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/104 (42%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+Q+ L + LGSGAFG+V E A ++ S KVAVK L+ A EK + E +MS
Sbjct: 268 RDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMS 327
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYL-RAKREF 575
+ H +++ LLG C P YII E GDL+ YL R K F
Sbjct: 328 HLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTF 371
Score = 31.9 bits (69), Expect = 2.7
Identities = 19/37 (51%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGS-QELGDFGLARDIYQN 777
VHRDLA RN L+ EG ++ DFGLARDI ++
Sbjct: 494 VHRDLAARNVLIC-----EGKLVKICDFGLARDIMRD 525
>U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein.
Length = 999
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/141 (36%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR-KGASEQEKTEFLKEAA 440
I R + L K LG G FG V EG +Q +G+++ KVAVKT++ +S +E EFL EAA
Sbjct: 582 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSL--KVAVKTMKLDNSSHREIEEFLSEAA 639
Query: 441 LMSNFKHEHILRLLGVCLDNDPN-----YIIMELMEGGDLLSYLRAKREFXXXXXXXXXX 605
M +F H +++RLLGVC++ +I+ M+ GDL +YL R
Sbjct: 640 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSR-LETGPKHIPLQ 698
Query: 606 XXXNMCVDVTKGCRYLERDAF 668
VD+ G YL F
Sbjct: 699 TLLKFMVDIALGMEYLSNRNF 719
Score = 32.3 bits (70), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+F+HRDLA RNC++ + + + DFGL++ IY
Sbjct: 718 NFLHRDLAARNCML----RDDMTVCVADFGLSKKIY 749
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Frame = +3
Query: 216 QGVHCPTDAELASLP-HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR 392
+G + PT A + I ++T + LGSG FG V G R KVA+K +R
Sbjct: 348 KGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIR 401
Query: 393 KGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+GA +E +F++EA +M H +++L GVC P YI+ E ME G LL++LR ++
Sbjct: 402 EGAMCEE--DFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQ- 458
Query: 573 FXXXXXXXXXXXXXNMCVDVTKGCRYLERDAF 668
+MC DV +G YLER++F
Sbjct: 459 -----GHFSRDVLLSMCQDVCEGMEYLERNSF 485
Score = 36.3 bits (80), Expect = 0.12
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
F+HRDLA RNCLV+ G ++ DFG+AR
Sbjct: 485 FIHRDLAARNCLVSE----AGVVKVSDFGMAR 512
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Frame = +3
Query: 216 QGVHCPTDAELASLP-HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR 392
+G + PT A + I ++T + LGSG FG V G R KVA+K +R
Sbjct: 348 KGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIR 401
Query: 393 KGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+GA +E +F++EA +M H +++L GVC P YI+ E ME G LL++LR ++
Sbjct: 402 EGAMCEE--DFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQ- 458
Query: 573 FXXXXXXXXXXXXXNMCVDVTKGCRYLERDAF 668
+MC DV +G YLER++F
Sbjct: 459 -----GHFSRDVLLSMCQDVCEGMEYLERNSF 485
Score = 36.3 bits (80), Expect = 0.12
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
F+HRDLA RNCLV+ G ++ DFG+AR
Sbjct: 485 FIHRDLAARNCLVSE----AGVVKVSDFGMAR 512
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Frame = +3
Query: 216 QGVHCPTDAELASLP-HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLR 392
+G + PT A + I ++T + LGSG FG V G R KVA+K +R
Sbjct: 348 KGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIR 401
Query: 393 KGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+GA +E +F++EA +M H +++L GVC P YI+ E ME G LL++LR ++
Sbjct: 402 EGAMCEE--DFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQ- 458
Query: 573 FXXXXXXXXXXXXXNMCVDVTKGCRYLERDAF 668
+MC DV +G YLER++F
Sbjct: 459 -----GHFSRDVLLSMCQDVCEGMEYLERNSF 485
Score = 36.3 bits (80), Expect = 0.12
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
F+HRDLA RNCLV+ G ++ DFG+AR
Sbjct: 485 FIHRDLAARNCLVSE----AGVVKVSDFGMAR 512
>X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein
protein.
Length = 591
Score = 78.2 bits (184), Expect = 3e-14
Identities = 41/105 (39%), Positives = 61/105 (58%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + + VAVK L++ ASE + +F
Sbjct: 295 ACVHHIKRRDIVLKWELGEGAFGKVFLAESHNLLPEQDKMLVAVKALKE-ASESARQDFQ 353
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 354 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 398
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 439 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 471
>X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein.
Length = 503
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 207 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 265
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 266 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 310
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 351 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 383
>X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for
trk-2h oncogene. ).
Length = 439
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 143 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 201
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 202 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 246
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 287 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 319
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 323 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 381
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 382 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 426
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 467 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 499
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 77.8 bits (183), Expect = 4e-14
Identities = 45/99 (45%), Positives = 58/99 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I R I L K LGSG FGEV+EG+ T VAVKTL+ G+ + +FL+EA +
Sbjct: 229 IDRNSIQLLKRLGSGQFGEVWEGLWNNT------TPVAVKTLKPGS--MDPNDFLREAQI 280
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M N +H +++L VC DP YII ELM G L YL+
Sbjct: 281 MKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ 319
Score = 30.3 bits (65), Expect = 8.1
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+++HRDLA RN LV ++ DFGLAR
Sbjct: 349 NYIHRDLAARNVLVGE----HNIYKVADFGLAR 377
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 77.8 bits (183), Expect = 4e-14
Identities = 45/99 (45%), Positives = 58/99 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I R I L K LGSG FGEV+EG+ T VAVKTL+ G+ + +FL+EA +
Sbjct: 229 IDRNSIQLLKRLGSGQFGEVWEGLWNNT------TPVAVKTLKPGS--MDPNDFLREAQI 280
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M N +H +++L VC DP YII ELM G L YL+
Sbjct: 281 MKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ 319
Score = 30.3 bits (65), Expect = 8.1
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+++HRDLA RN LV ++ DFGLAR
Sbjct: 349 NYIHRDLAARNVLVGE----HNIYKVADFGLAR 377
>M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk
proto-oncogene insert of pLM6. ).
Length = 790
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 494 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 552
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 553 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 597
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 638 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 670
>BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein.
Length = 795
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 499 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 557
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 558 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 602
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 643 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 675
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 77.8 bits (183), Expect = 4e-14
Identities = 45/99 (45%), Positives = 58/99 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I R I L K LGSG FGEV+EG+ T VAVKTL+ G+ + +FL+EA +
Sbjct: 229 IDRNSIQLLKRLGSGQFGEVWEGLWNNT------TPVAVKTLKPGS--MDPNDFLREAQI 280
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M N +H +++L VC DP YII ELM G L YL+
Sbjct: 281 MKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ 319
Score = 30.3 bits (65), Expect = 8.1
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+++HRDLA RN LV ++ DFGLAR
Sbjct: 349 NYIHRDLAARNVLVGE----HNIYKVADFGLAR 377
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 77.8 bits (183), Expect = 4e-14
Identities = 45/99 (45%), Positives = 58/99 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I R I L K LGSG FGEV+EG+ T VAVKTL+ G+ + +FL+EA +
Sbjct: 229 IDRNSIQLLKRLGSGQFGEVWEGLWNNT------TPVAVKTLKPGS--MDPNDFLREAQI 280
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M N +H +++L VC DP YII ELM G L YL+
Sbjct: 281 MKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ 319
Score = 30.3 bits (65), Expect = 8.1
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+++HRDLA RN LV ++ DFGLAR
Sbjct: 349 NYIHRDLAARNVLVGE----HNIYKVADFGLAR 377
>AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 1 protein.
Length = 790
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 494 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 552
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 553 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 597
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 638 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 670
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 77.8 bits (183), Expect = 4e-14
Identities = 45/99 (45%), Positives = 58/99 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I R I L K LGSG FGEV+EG+ T VAVKTL+ G+ + +FL+EA +
Sbjct: 229 IDRNSIQLLKRLGSGQFGEVWEGLWNNT------TPVAVKTLKPGS--MDPNDFLREAQI 280
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
M N +H +++L VC DP YII ELM G L YL+
Sbjct: 281 MKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ 319
Score = 30.3 bits (65), Expect = 8.1
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +1
Query: 664 HFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+++HRDLA RN LV ++ DFGLAR
Sbjct: 349 NYIHRDLAARNVLVGE----HNIYKVADFGLAR 377
>AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein.
Length = 796
Score = 77.8 bits (183), Expect = 4e-14
Identities = 41/105 (39%), Positives = 60/105 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + HI+R I L LG GAFG+VF + VAVK L++ ASE + +F
Sbjct: 500 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE-ASESARQDFQ 558
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
+EA L++ +H+HI+R GVC + P ++ E M GDL +LR+
Sbjct: 559 REAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS 603
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/38 (60%), Positives = 29/38 (76%), Gaps = 1/38 (2%)
Frame = +1
Query: 661 MHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIY 771
+HFVHRDLA RNCLV G+G ++GDFG++RDIY
Sbjct: 644 LHFVHRDLATRNCLV-----GQGLVVKIGDFGMSRDIY 676
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 77.4 bits (182), Expect = 5e-14
Identities = 43/87 (49%), Positives = 56/87 (64%)
Frame = +3
Query: 300 GSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRL 479
G G +GEV+EGV ++ + VAVKTL++ E E EFLKEAA+M KH ++++L
Sbjct: 68 GGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEVE--EFLKEAAVMKEIKHPNLVQL 120
Query: 480 LGVCLDNDPNYIIMELMEGGDLLSYLR 560
LGVC P YII E M G+LL YLR
Sbjct: 121 LGVCTREPPFYIITEFMTYGNLLDYLR 147
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGS-QELGDFGLAR 762
++ +F+HRDLA RNCLV GE ++ DFGL+R
Sbjct: 174 EKKNFIHRDLAARNCLV-----GENHLVKVADFGLSR 205
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 76.6 bits (180), Expect = 9e-14
Identities = 43/110 (39%), Positives = 63/110 (57%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
PT A + I++ K +G+G FGEV G R S + VA+KTL+ G +E+
Sbjct: 605 PTQAVHEFAKELDATNISIDKVVGAGEFGEVCSG--RLKLPSKKEISVAIKTLKVGYTEK 662
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
++ +FL EA++M F H +I+RL GV + P I+ E ME G L S+LR
Sbjct: 663 QRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M +VHRDLA RN L+ N ++ DFGL+R
Sbjct: 739 DMGYVHRDLAARNILI----NSNLVCKVSDFGLSR 769
>M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth
factor A receptor protein.
Length = 1089
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L + LGSGAFG+V EG A ++ S KVAVK L+ A EK + E +M+
Sbjct: 590 RDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 649
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ H +I+ LLG C + P YII E GDL++YL R+
Sbjct: 650 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRD 691
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/33 (57%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN L+ A G+ ++ DFGLARDI
Sbjct: 815 VHRDLAARNVLL---AQGK-IVKICDFGLARDI 843
>M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth
factor receptor A chain protein.
Length = 1089
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L + LGSGAFG+V EG A ++ S KVAVK L+ A EK + E +M+
Sbjct: 590 RDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 649
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ H +I+ LLG C + P YII E GDL++YL R+
Sbjct: 650 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRD 691
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/33 (57%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN L+ A G+ ++ DFGLARDI
Sbjct: 815 VHRDLAARNVLL---AQGK-IVKICDFGLARDI 843
>D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived
growth factor receptor protein.
Length = 1089
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L + LGSGAFG+V EG A ++ S KVAVK L+ A EK + E +M+
Sbjct: 590 RDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 649
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ H +I+ LLG C + P YII E GDL++YL R+
Sbjct: 650 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRD 691
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/33 (57%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN L+ A G+ ++ DFGLARDI
Sbjct: 815 VHRDLAARNVLL---AQGK-IVKICDFGLARDI 843
>BC063414-1|AAH63414.1| 743|Homo sapiens PDGFRA protein protein.
Length = 743
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L + LGSGAFG+V EG A ++ S KVAVK L+ A EK + E +M+
Sbjct: 590 RDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 649
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ H +I+ LLG C + P YII E GDL++YL R+
Sbjct: 650 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRD 691
>AY229892-1|AAP69563.1| 849|Homo sapiens FIP1L1/PDGFRA fusion
protein protein.
Length = 849
Score = 76.6 bits (180), Expect = 9e-14
Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L + LGSGAFG+V EG A ++ S KVAVK L+ A EK + E +M+
Sbjct: 350 RDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 409
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ H +I+ LLG C + P YII E GDL++YL R+
Sbjct: 410 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRD 451
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/33 (57%), Positives = 23/33 (69%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
VHRDLA RN L+ A G+ ++ DFGLARDI
Sbjct: 575 VHRDLAARNVLL---AQGK-IVKICDFGLARDI 603
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 76.6 bits (180), Expect = 9e-14
Identities = 43/110 (39%), Positives = 63/110 (57%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
PT A + I++ K +G+G FGEV G R S + VA+KTL+ G +E+
Sbjct: 605 PTQAVHEFAKELDATNISIDKVVGAGEFGEVCSG--RLKLPSKKEISVAIKTLKVGYTEK 662
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
++ +FL EA++M F H +I+RL GV + P I+ E ME G L S+LR
Sbjct: 663 QRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M +VHRDLA RN L+ N ++ DFGL+R
Sbjct: 739 DMGYVHRDLAARNILI----NSNLVCKVSDFGLSR 769
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 629 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 686
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 687 MPVMILTEFMENGALDSFLR 706
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 733 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 768
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 629 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 686
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 687 MPVMILTEFMENGALDSFLR 706
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 733 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 768
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 427 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 486
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 487 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 544
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 545 MPVMILTEFMENGALDSFLR 564
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 591 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 626
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 629 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 686
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 687 MPVMILTEFMENGALDSFLR 706
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 733 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 768
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 629 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 686
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 687 MPVMILTEFMENGALDSFLR 706
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 733 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 768
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 629 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 686
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 687 MPVMILTEFMENGALDSFLR 706
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 733 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 768
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +3
Query: 144 GPDVELATLRHELPIRHSTNILYNQGVH-CPTDAELASLPHIRREQITLSKFLGSGAFGE 320
G + E + + I H T + + + P +A I + + + +G+G FGE
Sbjct: 568 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 627
Query: 321 VFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDN 500
V G R ++ VA+KTL+ G +E+++ EFL EA++M F+H +I+RL GV ++
Sbjct: 628 VCRG--RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNS 685
Query: 501 DPNYIIMELMEGGDLLSYLR 560
P I+ E ME G L S+LR
Sbjct: 686 MPVMILTEFMENGALDSFLR 705
Score = 34.7 bits (76), Expect = 0.38
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
EM +VHRDLA RN LV N ++ DFGL+R + +N
Sbjct: 732 EMSYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEEN 767
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/94 (41%), Positives = 61/94 (64%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV++G + + G + VA+KTL+ G SE+++ +FL EA++M F
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLK-LPGKR-EIYVAIKTLKAGYSEKQRRDFLSEASIMGQFD 676
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +I+RL GV + P II E ME G L S+LR
Sbjct: 677 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Score = 33.5 bits (73), Expect = 0.87
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
EM++VHRDLA RN LV N ++ DFGL+R
Sbjct: 737 EMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 767
>L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase
protein.
Length = 1052
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/102 (38%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I+RE+I L + +G G FG+V +G+ + VA+KT + S+ + +FL+EA
Sbjct: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPAL--AVAIKTCKNCTSDSVREKFLQEALT 474
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H HI++L+GV +N P +IIMEL G+L S+L+ ++
Sbjct: 475 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK 515
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
FVHRD+A RN LV + +LGDFGL+R
Sbjct: 542 FVHRDIAARNVLV----SSNDCVKLGDFGLSR 569
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/94 (41%), Positives = 61/94 (64%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV++G + + G + VA+KTL+ G SE+++ +FL EA++M F
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLK-LPGKR-EIYVAIKTLKAGYSEKQRRDFLSEASIMGQFD 676
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +I+RL GV + P II E ME G L S+LR
Sbjct: 677 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
EM++VHRDLA RN L+ N ++ DFGL+R
Sbjct: 737 EMNYVHRDLAARNILL----NSNLVCKVSDFGLSR 767
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 433 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 490
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 491 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 550
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 551 VGKPMCLLFEYMAYGDLNEFLRS 573
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 622 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 655
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 443 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 500
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 501 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 560
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 561 VGKPMCLLFEYMAYGDLNEFLRS 583
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 632 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 665
>BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein.
Length = 1006
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/102 (38%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I+RE+I L + +G G FG+V +G+ + VA+KT + S+ + +FL+EA
Sbjct: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPAL--AVAIKTCKNCTSDSVREKFLQEALT 474
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H HI++L+GV +N P +IIMEL G+L S+L+ ++
Sbjct: 475 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK 515
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
FVHRD+A RN LV + +LGDFGL+R
Sbjct: 542 FVHRDIAARNVLV----SSNDCVKLGDFGLSR 569
>BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein.
Length = 680
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/102 (38%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I+RE+I L + +G G FG+V +G+ + VA+KT + S+ + +FL+EA
Sbjct: 45 IQRERIELGRCIGEGQFGDVHQGIYMSPENPAL--AVAIKTCKNCTSDSVREKFLQEALT 102
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H HI++L+GV +N P +IIMEL G+L S+L+ ++
Sbjct: 103 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK 143
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
FVHRD+A RN LV + +LGDFGL+R
Sbjct: 170 FVHRDIAARNVLV----SSNDCVKLGDFGLSR 197
>AL513328-2|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 535 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 592
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 593 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 652
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 653 VGKPMCLLFEYMAYGDLNEFLRS 675
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 724 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 757
>AL513328-1|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 527 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 584
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 585 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 644
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 645 VGKPMCLLFEYMAYGDLNEFLRS 667
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 716 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 749
>AL157881-3|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 535 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 592
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 593 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 652
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 653 VGKPMCLLFEYMAYGDLNEFLRS 675
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 724 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 757
>AL157881-2|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 527 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 584
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 585 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 644
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 645 VGKPMCLLFEYMAYGDLNEFLRS 667
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 716 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 749
>AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens
cDNA FLJ37680 fis, clone BRHIP2012923, highly similar to
FOCAL ADHESION KINASE 1 (EC 2.7.1.112). ).
Length = 720
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/102 (38%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I+RE+I L + +G G FG+V +G+ + VA+KT + S+ + +FL+EA
Sbjct: 85 IQRERIELGRCIGEGQFGDVHQGIYMSPENPAL--AVAIKTCKNCTSDSVREKFLQEALT 142
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H HI++L+GV +N P +IIMEL G+L S+L+ ++
Sbjct: 143 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK 183
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
FVHRD+A RN LV + +LGDFGL+R
Sbjct: 210 FVHRDIAARNVLV----SSNDCVKLGDFGLSR 237
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/94 (41%), Positives = 61/94 (64%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV++G + + G + VA+KTL+ G SE+++ +FL EA++M F
Sbjct: 608 VKIEEVIGAGEFGEVYKGRLK-LPGKR-EIYVAIKTLKAGYSEKQRRDFLSEASIMGQFD 665
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +I+RL GV + P II E ME G L S+LR
Sbjct: 666 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 699
Score = 33.5 bits (73), Expect = 0.87
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
EM++VHRDLA RN LV N ++ DFGL+R
Sbjct: 726 EMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 756
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/94 (41%), Positives = 61/94 (64%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV++G + + G + VA+KTL+ G SE+++ +FL EA++M F
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLK-LPGKR-EIYVAIKTLKAGYSEKQRRDFLSEASIMGQFD 676
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +I+RL GV + P II E ME G L S+LR
Sbjct: 677 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Score = 33.5 bits (73), Expect = 0.87
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
EM++VHRDLA RN LV N ++ DFGL+R
Sbjct: 737 EMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 767
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/143 (37%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +3
Query: 138 RRGPDVELATLRHELPI-RHSTNILYNQGVHCPTDAELASLPHIRREQITLSKFLGSGAF 314
R V L TL EL + R N +Y Q + + +L SL + R I + +G GAF
Sbjct: 529 RESAAVTLTTLPSELLLDRLHPNPMY-QRMPLLLNPKLLSLEY-PRNNIEYVRDIGEGAF 586
Query: 315 GEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCL 494
G VF+ A + T VAVK L++ AS + +F +EAALM+ F + +I++LLGVC
Sbjct: 587 GRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA 646
Query: 495 DNDPNYIIMELMEGGDLLSYLRA 563
P ++ E M GDL +LR+
Sbjct: 647 VGKPMCLLFEYMAYGDLNEFLRS 669
Score = 39.5 bits (88), Expect = 0.013
Identities = 20/38 (52%), Positives = 24/38 (63%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
E FVHRDLA RNCLV ++ DFGL+R+IY
Sbjct: 718 ERKFVHRDLATRNCLVGENM----VVKIADFGLSRNIY 751
>AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine
kinase 2 isoform b variant protein.
Length = 1007
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/102 (38%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I+RE+I L + +G G FG+V +G+ + VA+KT + S+ + +FL+EA
Sbjct: 369 IQRERIELGRCIGEGQFGDVHQGIYMSPENPAL--AVAIKTCKNCTSDSVREKFLQEALT 426
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H HI++L+GV +N P +IIMEL G+L S+L+ ++
Sbjct: 427 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK 467
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
FVHRD+A RN LV + +LGDFGL+R
Sbjct: 494 FVHRDIAARNVLV----SSNDCVKLGDFGLSR 521
>AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine
kinase 2 isoform b variant protein.
Length = 975
Score = 75.4 bits (177), Expect = 2e-13
Identities = 39/102 (38%), Positives = 63/102 (61%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I+RE+I L + +G G FG+V +G+ + VA+KT + S+ + +FL+EA
Sbjct: 337 IQRERIELGRCIGEGQFGDVHQGIYMSPENPAL--AVAIKTCKNCTSDSVREKFLQEALT 394
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M F H HI++L+GV +N P +IIMEL G+L S+L+ ++
Sbjct: 395 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK 435
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
FVHRD+A RN LV + +LGDFGL+R
Sbjct: 462 FVHRDIAARNVLV----SSNDCVKLGDFGLSR 489
>X15786-1|CAA33787.1| 899|Homo sapiens retII protein.
Length = 899
Score = 74.9 bits (176), Expect = 3e-13
Identities = 48/143 (33%), Positives = 71/143 (49%), Gaps = 3/143 (2%)
Frame = +3
Query: 153 VELATLRHELPI-RHSTNILYNQGVHCPTDAELASLP--HIRREQITLSKFLGSGAFGEV 323
+EL LRHE + R L Q +H +EL P R+ + L K LG G FG+V
Sbjct: 466 MELEELRHEKEMQREEIQKLMGQ-IH-QLRSELQEDPKWEFPRKNLVLGKTLGEGEFGKV 523
Query: 324 FEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFKHEHILRLLGVCLDND 503
+ A + G T VAVK L++ AS E + L E ++ H H+++L G C +
Sbjct: 524 VKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDG 583
Query: 504 PNYIIMELMEGGDLLSYLRAKRE 572
P +I+E + G L +LR R+
Sbjct: 584 PLLLIVEYAKYGSLRGFLRESRK 606
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 652 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 686
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 74.9 bits (176), Expect = 3e-13
Identities = 40/94 (42%), Positives = 59/94 (62%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
I++ K +G+G FGEV G R S + VA+KTL+ G +E+++ +FL EA++M F
Sbjct: 621 ISIDKVVGAGEFGEVCSG--RLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFD 678
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +I+RL GV + P I+ E ME G L S+LR
Sbjct: 679 HPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M +VHRDLA RN L+ N ++ DFGL+R
Sbjct: 739 DMGYVHRDLAARNILI----NSNLVCKVSDFGLSR 769
>BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating factor
1 receptor, formerly McDonough feline sarcoma viral (
protein.
Length = 972
Score = 73.7 bits (173), Expect = 7e-13
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R + K LG+GAFG+V E A + KVAVK L+ A EK + E +MS
Sbjct: 579 RNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKESLMSELKIMS 638
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ +HE+I+ LLG C P +I E GDLL++LR K E
Sbjct: 639 HLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAE 680
Score = 34.7 bits (76), Expect = 0.38
Identities = 18/33 (54%), Positives = 24/33 (72%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRD+A RN L+ NG ++ +GDFGLARDI
Sbjct: 775 IHRDVAARNVLLT---NGHVAK-IGDFGLARDI 803
>X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for
c-fms proto-oncogene. ).
Length = 972
Score = 73.3 bits (172), Expect = 9e-13
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R + K LG+GAFG+V E A + KVAVK L+ A EK + E +MS
Sbjct: 579 RNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMS 638
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ +HE+I+ LLG C P +I E GDLL++LR K E
Sbjct: 639 HLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAE 680
Score = 34.7 bits (76), Expect = 0.38
Identities = 18/33 (54%), Positives = 24/33 (72%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRD+A RN L+ NG ++ +GDFGLARDI
Sbjct: 775 IHRDVAARNVLLT---NGHVAK-IGDFGLARDI 803
>U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein.
Length = 972
Score = 73.3 bits (172), Expect = 9e-13
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R + K LG+GAFG+V E A + KVAVK L+ A EK + E +MS
Sbjct: 579 RNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMS 638
Query: 450 NF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
+ +HE+I+ LLG C P +I E GDLL++LR K E
Sbjct: 639 HLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAE 680
Score = 34.7 bits (76), Expect = 0.38
Identities = 18/33 (54%), Positives = 24/33 (72%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRD+A RN L+ NG ++ +GDFGLARDI
Sbjct: 775 IHRDVAARNVLLT---NGHVAK-IGDFGLARDI 803
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/131 (32%), Positives = 68/131 (51%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++ K +GSG FG V G R +VA+K + +G+ +E +F++EA +M
Sbjct: 270 ELAFIKEIGSGQFGVVHLGEWRS------HIQVAIKAINEGSMSEE--DFIEEAKVMMKL 321
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVC+ P YI+ E ME G LL+YLR + ++C D+
Sbjct: 322 SHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENK------GKLRKEMLLSVCQDIC 375
Query: 636 KGCRYLERDAF 668
+G YLER+ +
Sbjct: 376 EGMEYLERNGY 386
Score = 31.1 bits (67), Expect = 4.7
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
++HRDLA RNCLV+ ++ DFG+ R
Sbjct: 386 YIHRDLAARNCLVSSTC----IVKISDFGMTR 413
>AC068970-1|AAX88856.1| 136|Homo sapiens unknown protein.
Length = 136
Score = 72.9 bits (171), Expect = 1e-12
Identities = 39/108 (36%), Positives = 62/108 (57%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A L ++ ++ K LGSGAFG V++G+ G TV VA+K L + + EF+
Sbjct: 15 AQLRILKETELKRVKVLGSGAFGTVYKGIWVP-EGETVKIPVAIKILNETTGPKANVEFM 73
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
EA +M++ H H++RLLGVCL + ++ +LM G LL Y+ ++
Sbjct: 74 DEALIMASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCLLEYVHEHKD 120
>Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein.
Length = 622
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 275 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 334
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 335 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 377
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 420 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 449
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 620 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 649
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 384 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 443
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 444 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 486
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 529 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 558
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 620 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 649
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 473 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 532
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 533 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 575
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 618 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 647
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 386 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 445
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 446 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 488
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 531 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 560
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 620 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 649
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 620 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 649
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 72.1 bits (169), Expect = 2e-12
Identities = 46/127 (36%), Positives = 68/127 (53%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++T + +GSG FG V G +N KVA+KT+R+GA +E +F++EA +M
Sbjct: 362 ELTFVQEIGSGQFGLVHLGY--WLNKD----KVAIKTIREGAMSEE--DFIEEAEVMMKL 413
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVCL+ P ++ E ME G L YLR +R MC+DV
Sbjct: 414 SHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMCLDVC 467
Query: 636 KGCRYLE 656
+G YLE
Sbjct: 468 EGMAYLE 474
Score = 30.3 bits (65), Expect = 8.1
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQ-ELGDFGLAR 762
+E +HRDLA RNCLV GE ++ DFG+ R
Sbjct: 474 EEACVIHRDLAARNCLV-----GENQVIKVSDFGMTR 505
>M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 662
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 620 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 649
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 473 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 532
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 533 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 575
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 618 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 647
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 384 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 443
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 444 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 486
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 529 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 558
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 473 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 532
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 533 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 575
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 618 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 647
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 384 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 443
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 444 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 486
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 529 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 558
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 386 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 445
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 446 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 488
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 531 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 560
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 72.1 bits (169), Expect = 2e-12
Identities = 46/127 (36%), Positives = 68/127 (53%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++T + +GSG FG V G +N KVA+KT+R+GA +E +F++EA +M
Sbjct: 362 ELTFVQEIGSGQFGLVHLGY--WLNKD----KVAIKTIREGAMSEE--DFIEEAEVMMKL 413
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVCL+ P ++ E ME G L YLR +R MC+DV
Sbjct: 414 SHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMCLDVC 467
Query: 636 KGCRYLE 656
+G YLE
Sbjct: 468 EGMAYLE 474
Score = 30.3 bits (65), Expect = 8.1
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQ-ELGDFGLAR 762
+E +HRDLA RNCLV GE ++ DFG+ R
Sbjct: 474 EEACVIHRDLAARNCLV-----GENQVIKVSDFGMTR 505
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 72.1 bits (169), Expect = 2e-12
Identities = 46/127 (36%), Positives = 68/127 (53%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++T + +GSG FG V G +N KVA+KT+R+GA +E +F++EA +M
Sbjct: 362 ELTFVQEIGSGQFGLVHLGY--WLNKD----KVAIKTIREGAMSEE--DFIEEAEVMMKL 413
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVCL+ P ++ E ME G L YLR +R MC+DV
Sbjct: 414 SHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMCLDVC 467
Query: 636 KGCRYLE 656
+G YLE
Sbjct: 468 EGMAYLE 474
Score = 30.3 bits (65), Expect = 8.1
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQ-ELGDFGLAR 762
+E +HRDLA RNCLV GE ++ DFG+ R
Sbjct: 474 EEACVIHRDLAARNCLV-----GENQVIKVSDFGMTR 505
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 72.1 bits (169), Expect = 2e-12
Identities = 46/127 (36%), Positives = 68/127 (53%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++T + +GSG FG V G +N KVA+KT+R+GA +E +F++EA +M
Sbjct: 362 ELTFVQEIGSGQFGLVHLGY--WLNKD----KVAIKTIREGAMSEE--DFIEEAEVMMKL 413
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVCL+ P ++ E ME G L YLR +R MC+DV
Sbjct: 414 SHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMCLDVC 467
Query: 636 KGCRYLE 656
+G YLE
Sbjct: 468 EGMAYLE 474
Score = 30.3 bits (65), Expect = 8.1
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQ-ELGDFGLAR 762
+E +HRDLA RNCLV GE ++ DFG+ R
Sbjct: 474 EEACVIHRDLAARNCLV-----GENQVIKVSDFGMTR 505
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 72.1 bits (169), Expect = 2e-12
Identities = 46/127 (36%), Positives = 68/127 (53%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++T + +GSG FG V G +N KVA+KT+R+GA +E +F++EA +M
Sbjct: 362 ELTFVQEIGSGQFGLVHLGY--WLNKD----KVAIKTIREGAMSEE--DFIEEAEVMMKL 413
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVCL+ P ++ E ME G L YLR +R MC+DV
Sbjct: 414 SHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMCLDVC 467
Query: 636 KGCRYLE 656
+G YLE
Sbjct: 468 EGMAYLE 474
Score = 30.3 bits (65), Expect = 8.1
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Frame = +1
Query: 655 KEMHFVHRDLACRNCLVAHRANGEGSQ-ELGDFGLAR 762
+E +HRDLA RNCLV GE ++ DFG+ R
Sbjct: 474 EEACVIHRDLAARNCLV-----GENQVIKVSDFGMTR 505
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 384 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 443
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 444 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 486
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 529 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 558
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 473 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 532
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 533 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 575
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 618 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 647
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 473 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 532
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 533 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 575
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 618 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 647
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 475 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 534
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 535 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 577
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 620 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 649
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++ L K LG G FG+V E + + TKVAVK L+ A+E++ ++ + E +
Sbjct: 467 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 526
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YL+A+R
Sbjct: 527 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 569
Score = 35.1 bits (77), Expect = 0.29
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDIY 771
+HRDLA RN LV + ++ DFGLARDI+
Sbjct: 612 IHRDLAARNVLVTE----DNVMKIADFGLARDIH 641
>X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein.
Length = 435
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 84 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 143
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 144 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 184
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 230 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 264
>X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret
proto-oncogene mRNA for tyrosine kinase. ).
Length = 860
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 467 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 526
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 527 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 567
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 613 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 647
>M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA
encoding a tyrosine kinase, partial cds. ).
Length = 805
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 454 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 513
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 514 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 554
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 600 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 634
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 245 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 304
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 305 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 345
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 391 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 425
>DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein
protein.
Length = 776
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 383 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 442
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 443 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 483
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 529 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 563
>BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene protein.
Length = 1072
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 821
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 867 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 901
>AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase
receptor protein.
Length = 1091
Score = 71.7 bits (168), Expect = 3e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 697 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 756
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 757 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 797
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 843 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 877
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 790 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 848
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 909 ALCTQVALGMEHLSNNRF 926
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 926 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 958
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 790 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 848
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 909 ALCTQVALGMEHLSNNRF 926
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 926 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 958
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 790 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 848
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 909 ALCTQVALGMEHLSNNRF 926
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 926 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 958
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 734 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 792
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 793 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 852
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 853 ALCTQVALGMEHLSNNRF 870
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 870 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 902
>AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor
precursor PTK7-3 protein.
Length = 940
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 660 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 718
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 719 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 778
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 779 ALCTQVALGMEHLSNNRF 796
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 796 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 828
>AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor
precursor PTK7-2 protein.
Length = 1030
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 750 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 808
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 809 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 868
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 869 ALCTQVALGMEHLSNNRF 886
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 886 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 918
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 790 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 848
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 909 ALCTQVALGMEHLSNNRF 926
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 926 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 958
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +3
Query: 261 HIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAA 440
H R + LG FGEVF A+ + +T V VK+L+ EQ++ +F +E
Sbjct: 790 HFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELE 848
Query: 441 LMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR--AKREFXXXXXXXXXXXXX 614
+ H +++RLLG+C + +P+Y+++E ++ GDL +LR ++
Sbjct: 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908
Query: 615 NMCVDVTKGCRYLERDAF 668
+C V G +L + F
Sbjct: 909 ALCTQVALGMEHLSNNRF 926
Score = 33.9 bits (74), Expect = 0.66
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLARDIYQN 777
FVH+DLA RNCLV + + ++ GL++D+Y +
Sbjct: 926 FVHKDLAARNCLV----SAQRQVKVSALGLSKDVYNS 958
>Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein.
Length = 821
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 478 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 537
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 538 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 580
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 623 IHRDLAARNVLVTE----NNVMKIADFGLARDI 651
>X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor
(FGR) receptor protein.
Length = 769
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA for
fibroblast growth factor receptor-BEK. ).
Length = 821
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 478 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 537
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 538 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 580
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 623 IHRDLAARNVLVTE----NNVMKIADFGLARDI 651
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 70.9 bits (166), Expect = 5e-12
Identities = 41/131 (31%), Positives = 67/131 (51%)
Frame = +3
Query: 276 QITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNF 455
++ K +GSG FG V G R +VA+K + +G+ +E +F++EA +M
Sbjct: 270 ELAFIKXIGSGQFGVVHLGEWRS------HIQVAIKAINEGSMSEE--DFIEEAKVMMKL 321
Query: 456 KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXXXXNMCVDVT 635
H +++L GVC+ P YI+ E ME G LL+YLR + ++C +
Sbjct: 322 SHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENK------GKLRKEMLLSVCQXIC 375
Query: 636 KGCRYLERDAF 668
+G YLER+ +
Sbjct: 376 EGMEYLERNGY 386
Score = 31.1 bits (67), Expect = 4.7
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = +1
Query: 667 FVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
++HRDLA RNCLV+ ++ DFG+ R
Sbjct: 386 YIHRDLAARNCLVSSTC----IVKISDFGMTR 413
>M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor
receptor protein.
Length = 705
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 362 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 421
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 422 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 464
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 507 IHRDLAARNVLVTE----NNVMKIADFGLARDI 535
>M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor
receptor protein.
Length = 821
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 478 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 537
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 538 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 580
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 623 IHRDLAARNVLVTE----NNVMKIADFGLARDI 651
>M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth factor
receptor protein.
Length = 822
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein.
Length = 822
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human
heparin-binding growth factor receptor K-sam mRNA. ).
Length = 682
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 388 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 447
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 448 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 490
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 533 IHRDLAARNVLVTE----NNVMKIADFGLARDI 561
>M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary
thyroid carcinoma-encoded protein mRNA, complete cds. ).
Length = 503
Score = 70.9 bits (166), Expect = 5e-12
Identities = 35/101 (34%), Positives = 54/101 (53%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMS 449
R+ + L K LG G FG+V + A + G T VAVK L++ AS E + L E ++
Sbjct: 110 RKNLVLGKTLGEGEFGKVVKATAFHLKGRGGYTTVAVKMLKENASPSELRDLLSEFNVLK 169
Query: 450 NFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKRE 572
H H+++L G C + P +I+E + G L +LR R+
Sbjct: 170 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 210
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEG-SQELGDFGLARDIYQ 774
EM VHRDLA RN LVA EG ++ DFGL+RD+Y+
Sbjct: 256 EMKLVHRDLAARNILVA-----EGRKMKISDFGLSRDVYE 290
>DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth factor
receptor 2 (bacteria-expressed kinase, keratinocyte gr
protein.
Length = 785
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 535
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 536 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 578
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 621 IHRDLAARNVLVTE----NNVMKIADFGLARDI 649
>BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein.
Length = 704
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 361 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 420
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 421 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 463
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 506 IHRDLAARNVLVTE----NNVMKIADFGLARDI 534
>AY065844-1|AAL40893.1| 106|Homo sapiens truncated receptor
tyrosine kinase TrkC protein.
Length = 106
Score = 70.9 bits (166), Expect = 5e-12
Identities = 37/93 (39%), Positives = 54/93 (58%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
I L + LG GAFG+VF ++ + VAVK L+ K +F +EA L++N +
Sbjct: 3 IVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQ 61
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYL 557
HEHI++ GVC D DP ++ E M+ GDL +L
Sbjct: 62 HEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFL 94
>AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC3 protein.
Length = 766
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 535
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 536 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 578
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 621 IHRDLAARNVLVTE----NNVMKIADFGLARDI 649
>AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC2 protein.
Length = 785
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 535
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 536 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 578
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 621 IHRDLAARNVLVTE----NNVMKIADFGLARDI 649
>AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth factor
receptor 2 isoform BEK protein.
Length = 819
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 535
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 536 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 578
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 621 IHRDLAARNVLVTE----NNVMKIADFGLARDI 649
>AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth factor
receptor 2 isoform KGFR protein.
Length = 820
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 477 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 536
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 537 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 579
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 622 IHRDLAARNVLVTE----NNVMKIADFGLARDI 650
>AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth factor
receptor 2 isoform IgIIIc isoform protein.
Length = 554
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 265 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 324
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 325 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 367
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 410 IHRDLAARNVLVTE----NNVMKIADFGLARDI 438
>AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth receptor
2 IgIIIb isoform protein.
Length = 555
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 266 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 325
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 326 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 368
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 411 IHRDLAARNVLVTE----NNVMKIADFGLARDI 439
>AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein.
Length = 709
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 366 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 425
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 426 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 468
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 511 IHRDLAARNVLVTE----NNVMKIADFGLARDI 539
>AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein.
Length = 768
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein.
Length = 817
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein.
Length = 771
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein.
Length = 830
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein.
Length = 819
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein.
Length = 819
Score = 70.9 bits (166), Expect = 5e-12
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Frame = +3
Query: 270 REQITLSKFLGSGAFGEVF--EGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
R+++TL K LG G FG+V E V + VAVK L+ A+E++ ++ + E +
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 538
Query: 444 MSNF-KHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKR 569
M KH++I+ LLG C + P Y+I+E G+L YLRA+R
Sbjct: 539 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR 581
Score = 33.5 bits (73), Expect = 0.87
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +1
Query: 670 VHRDLACRNCLVAHRANGEGSQELGDFGLARDI 768
+HRDLA RN LV ++ DFGLARDI
Sbjct: 624 IHRDLAARNVLVTE----NNVMKIADFGLARDI 652
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine
kinase protein.
Length = 1037
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/110 (35%), Positives = 62/110 (56%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
P A I IT+ + +G+G FGEV G + + G + VA+KTL+ G +E+
Sbjct: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLK-LPGKR-ELPVAIKTLKVGYTEK 716
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
++ +FL EA++M F H +I+ L GV + P I+ E ME G L ++L+
Sbjct: 717 QRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 766
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M +VHRDLA RN L+ N ++ DFGL+R
Sbjct: 793 DMGYVHRDLAARNILI----NSNLVCKVSDFGLSR 823
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 70.5 bits (165), Expect = 6e-12
Identities = 44/136 (32%), Positives = 69/136 (50%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + ++ ++ K LGSGAFG V++G+ +G V VA+K LR+ S + E L
Sbjct: 710 AQMRILKETELRKVKVLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEIL 768
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXX 608
EA +M+ ++ RLLG+CL + ++ +LM G LL ++R R
Sbjct: 769 DEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCLLDHVRENR------GRLGSQD 821
Query: 609 XXNMCVDVTKGCRYLE 656
N C+ + KG YLE
Sbjct: 822 LLNWCMQIAKGMSYLE 837
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 70.5 bits (165), Expect = 6e-12
Identities = 45/100 (45%), Positives = 58/100 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE I L K LG+G FGEV+ G N S TKVAVKTL+ G + FL+EA L
Sbjct: 221 IPRESIKLVKRLGAGQFGEVWMG---YYNNS---TKVAVKTLKPGTMSVQ--AFLEEANL 272
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
M +H+ ++RL V +P YII E M G LL +L++
Sbjct: 273 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKS 312
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 70.5 bits (165), Expect = 6e-12
Identities = 45/100 (45%), Positives = 58/100 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE I L K LG+G FGEV+ G N S TKVAVKTL+ G + FL+EA L
Sbjct: 242 IPRESIKLVKRLGAGQFGEVWMG---YYNNS---TKVAVKTLKPGTMSVQ--AFLEEANL 293
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
M +H+ ++RL V +P YII E M G LL +L++
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKS 333
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 70.5 bits (165), Expect = 6e-12
Identities = 44/136 (32%), Positives = 69/136 (50%)
Frame = +3
Query: 249 ASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFL 428
A + ++ ++ K LGSGAFG V++G+ +G V VA+K LR+ S + E L
Sbjct: 710 AQMRILKETELRKVKVLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEIL 768
Query: 429 KEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRAKREFXXXXXXXXXXX 608
EA +M+ ++ RLLG+CL + ++ +LM G LL ++R R
Sbjct: 769 DEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCLLDHVRENR------GRLGSQD 821
Query: 609 XXNMCVDVTKGCRYLE 656
N C+ + KG YLE
Sbjct: 822 LLNWCMQIAKGMSYLE 837
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 70.5 bits (165), Expect = 6e-12
Identities = 36/94 (38%), Positives = 58/94 (61%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV G + + G + VA+KTL+ G +E+++ +FL EA++M F
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLK-LPGKR-EIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 679
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +++ L GV + P II E ME G L S+LR
Sbjct: 680 HPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 713
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 740 DMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 770
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/110 (35%), Positives = 62/110 (56%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
P A I IT+ + +G+G FGEV G + + G + VA+KTL+ G +E+
Sbjct: 613 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLK-LPGKR-ELPVAIKTLKVGYTEK 670
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
++ +FL EA++M F H +I+ L GV + P I+ E ME G L ++L+
Sbjct: 671 QRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 720
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M +VHRDLA RN L+ N ++ DFGL+R
Sbjct: 747 DMGYVHRDLAARNILI----NSNLVCKVSDFGLSR 777
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 70.5 bits (165), Expect = 6e-12
Identities = 36/94 (38%), Positives = 58/94 (61%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV G + + G + VA+KTL+ G +E+++ +FL EA++M F
Sbjct: 605 VKIEQVIGAGEFGEVCSGHLK-LPGKR-EIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 662
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +++ L GV + P II E ME G L S+LR
Sbjct: 663 HPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 696
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 723 DMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 753
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 70.5 bits (165), Expect = 6e-12
Identities = 36/94 (38%), Positives = 58/94 (61%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV G + + G + VA+KTL+ G +E+++ +FL EA++M F
Sbjct: 113 VKIEQVIGAGEFGEVCSGHLK-LPGKR-EIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 170
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +++ L GV + P II E ME G L S+LR
Sbjct: 171 HPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 204
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 231 DMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 261
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 70.5 bits (165), Expect = 6e-12
Identities = 36/94 (38%), Positives = 58/94 (61%)
Frame = +3
Query: 279 ITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAALMSNFK 458
+ + + +G+G FGEV G + + G + VA+KTL+ G +E+++ +FL EA++M F
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLK-LPGKR-EIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 673
Query: 459 HEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
H +++ L GV + P II E ME G L S+LR
Sbjct: 674 HPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 707
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +1
Query: 658 EMHFVHRDLACRNCLVAHRANGEGSQELGDFGLAR 762
+M++VHRDLA RN LV N ++ DFGL+R
Sbjct: 734 DMNYVHRDLAARNILV----NSNLVCKVSDFGLSR 764
>BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein
protein.
Length = 969
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/110 (35%), Positives = 62/110 (56%)
Frame = +3
Query: 231 PTDAELASLPHIRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQ 410
P A I IT+ + +G+G FGEV G + + G + VA+KTL+ G +E+
Sbjct: 591 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLK-LPGKR-ELPVAIKTLKVGYTEK 648
Query: 411 EKTEFLKEAALMSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLR 560
++ +FL EA++M F H +I+ L GV + P I+ E ME G L ++L+
Sbjct: 649 QRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 698
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 70.5 bits (165), Expect = 6e-12
Identities = 45/100 (45%), Positives = 58/100 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE I L K LG+G FGEV+ G N S TKVAVKTL+ G + FL+EA L
Sbjct: 242 IPRESIKLVKRLGAGQFGEVWMG---YYNNS---TKVAVKTLKPGTMSVQ--AFLEEANL 293
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
M +H+ ++RL V +P YII E M G LL +L++
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKS 333
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 70.5 bits (165), Expect = 6e-12
Identities = 45/100 (45%), Positives = 58/100 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE I L K LG+G FGEV+ G N S TKVAVKTL+ G + FL+EA L
Sbjct: 242 IPRESIKLVKRLGAGQFGEVWMG---YYNNS---TKVAVKTLKPGTMSVQ--AFLEEANL 293
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
M +H+ ++RL V +P YII E M G LL +L++
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKS 333
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 70.5 bits (165), Expect = 6e-12
Identities = 45/100 (45%), Positives = 58/100 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE I L K LG+G FGEV+ G N S TKVAVKTL+ G + FL+EA L
Sbjct: 242 IPRESIKLVKRLGAGQFGEVWMG---YYNNS---TKVAVKTLKPGTMSVQ--AFLEEANL 293
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
M +H+ ++RL V +P YII E M G LL +L++
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKS 333
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 70.5 bits (165), Expect = 6e-12
Identities = 45/100 (45%), Positives = 58/100 (58%)
Frame = +3
Query: 264 IRREQITLSKFLGSGAFGEVFEGVARQINGSTVDTKVAVKTLRKGASEQEKTEFLKEAAL 443
I RE I L K LG+G FGEV+ G N S TKVAVKTL+ G + FL+EA L
Sbjct: 242 IPRESIKLVKRLGAGQFGEVWMG---YYNNS---TKVAVKTLKPGTMSVQ--AFLEEANL 293
Query: 444 MSNFKHEHILRLLGVCLDNDPNYIIMELMEGGDLLSYLRA 563
M +H+ ++RL V +P YII E M G LL +L++
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKS 333
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,710,376
Number of Sequences: 237096
Number of extensions: 2052185
Number of successful extensions: 7546
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 5702
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6691
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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