Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-5817
(619 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC067812-1|AAH67812.1| 526|Homo sapiens cyclin L1 protein. 32 1.4
BC007081-1|AAH07081.1| 526|Homo sapiens cyclin L1 protein. 32 1.4
AY358663-1|AAQ89026.1| 299|Homo sapiens CCNL1 protein. 32 1.4
AF180920-1|AAD53184.1| 526|Homo sapiens cyclin L ania-6a protein. 32 1.4
BC110984-1|AAI10985.1| 514|Homo sapiens KPL2 protein protein. 31 2.5
AK058124-1|BAB71674.1| 514|Homo sapiens protein ( Homo sapiens ... 31 2.5
M96943-1|AAA36487.1| 1218|Homo sapiens profilaggrin protein. 30 5.7
M60494-1|AAA63244.1| 990|Homo sapiens profilaggrin protein. 30 5.7
D45906-1|BAA08312.1| 638|Homo sapiens LIMK-2 protein. 30 5.7
CR456513-1|CAG30399.1| 638|Homo sapiens LIMK2 protein. 30 5.7
BC013051-1|AAH13051.1| 686|Homo sapiens LIM domain kinase 2 pro... 30 5.7
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein. 30 5.7
AC002073-3|AAB54055.1| 733|Homo sapiens Lim kinase protein. 30 5.7
AC002073-2|AAB54056.1| 638|Homo sapiens Lim Kinase protein. 30 5.7
AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin va... 30 5.7
X99717-1|CAA68053.1| 754|Homo sapiens SRcyp protein protein. 30 7.5
U40763-1|AAB40347.1| 754|Homo sapiens CARS-Cyp protein. 30 7.5
BC111693-1|AAI11694.1| 739|Homo sapiens PPIG protein protein. 30 7.5
AC016772-2|AAY24233.1| 571|Homo sapiens unknown protein. 30 7.5
M60499-1|AAA63246.1| 465|Homo sapiens profilaggrin protein. 29 9.9
>BC067812-1|AAH67812.1| 526|Homo sapiens cyclin L1 protein.
Length = 526
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 503 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 330
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 495
Query: 329 KWEHDERKSTET*NFNRHHGGDRTG 255
+ + +S E + ++HHGG R+G
Sbjct: 496 RDRRERSRSFERSHKSKHHGGSRSG 520
>BC007081-1|AAH07081.1| 526|Homo sapiens cyclin L1 protein.
Length = 526
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 503 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 330
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 495
Query: 329 KWEHDERKSTET*NFNRHHGGDRTG 255
+ + +S E + ++HHGG R+G
Sbjct: 496 RDRRERSRSFERSHKSKHHGGSRSG 520
>AY358663-1|AAQ89026.1| 299|Homo sapiens CCNL1 protein.
Length = 299
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 503 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 330
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 211 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 268
Query: 329 KWEHDERKSTET*NFNRHHGGDRTG 255
+ + +S E + ++HHGG R+G
Sbjct: 269 RDRRERSRSFERSHKSKHHGGSRSG 293
>AF180920-1|AAD53184.1| 526|Homo sapiens cyclin L ania-6a protein.
Length = 526
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 503 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 330
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 495
Query: 329 KWEHDERKSTET*NFNRHHGGDRTG 255
+ + +S E + ++HHGG R+G
Sbjct: 496 RDRRERSRSFERSHKSKHHGGSRSG 520
>BC110984-1|AAI10985.1| 514|Homo sapiens KPL2 protein protein.
Length = 514
Score = 31.5 bits (68), Expect = 2.5
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
Frame = -1
Query: 610 KKSGQSLADPVKL*ESV--SGIQ*NR*SSNTSQREFGYEQSTAMEAVEPNSKITNT---- 449
KK + +AD +K E++ +Q +S TS G + + + I
Sbjct: 238 KKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRL 297
Query: 448 ERDIAAEYAEAKRRGPLNIPPLLNHNQIQDSEGDSREDATNGNTTSESQQKRKISIDIM 272
E D A KRR L + L+ H +++ RE+ +SQQ+R+I++ +M
Sbjct: 298 EEDAFAREQREKRRRKLLMDQLIAHEAQEEAY---REEQLINRLMRQSQQERRIAVQLM 353
>AK058124-1|BAB71674.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ25395 fis, clone TST02553. ).
Length = 514
Score = 31.5 bits (68), Expect = 2.5
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
Frame = -1
Query: 610 KKSGQSLADPVKL*ESV--SGIQ*NR*SSNTSQREFGYEQSTAMEAVEPNSKITNT---- 449
KK + +AD +K E++ +Q +S TS G + + + I
Sbjct: 238 KKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRL 297
Query: 448 ERDIAAEYAEAKRRGPLNIPPLLNHNQIQDSEGDSREDATNGNTTSESQQKRKISIDIM 272
E D A KRR L + L+ H +++ RE+ +SQQ+R+I++ +M
Sbjct: 298 EEDAFAREQREKRRRKLLMDQLIAHEAQEEAY---REEQLINRLMRQSQQERRIAVQLM 353
>M96943-1|AAA36487.1| 1218|Homo sapiens profilaggrin protein.
Length = 1218
Score = 30.3 bits (65), Expect = 5.7
Identities = 15/58 (25%), Positives = 26/58 (44%)
Frame = -3
Query: 446 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 273
TR R+G + + +H+A+ + Q R G RG + H E+ + + HH
Sbjct: 813 TRRRQGSHHDQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHH 870
Score = 29.9 bits (64), Expect = 7.5
Identities = 20/76 (26%), Positives = 32/76 (42%)
Frame = -3
Query: 500 TEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWE 321
+ + HG + +D G+RH R E + H+A + QS TR RG
Sbjct: 318 SRNHHGSAWEQSRD---GSRHPRS--HDEDRASHGHSADSSRQSGTRHAETSSRGQTASS 372
Query: 320 HDERKSTET*NFNRHH 273
H++ +S+ HH
Sbjct: 373 HEQARSSAGERHGSHH 388
>M60494-1|AAA63244.1| 990|Homo sapiens profilaggrin protein.
Length = 990
Score = 30.3 bits (65), Expect = 5.7
Identities = 15/58 (25%), Positives = 26/58 (44%)
Frame = -3
Query: 446 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 273
TR R+G + + +H+A+ + Q R G RG + H E+ + + HH
Sbjct: 591 TRRRQGSHHDQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHH 648
Score = 29.9 bits (64), Expect = 7.5
Identities = 20/76 (26%), Positives = 32/76 (42%)
Frame = -3
Query: 500 TEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWE 321
+ + HG + +D G+RH R E + H+A + QS TR RG
Sbjct: 96 SRNHHGSAWEQSRD---GSRHPRS--HDEDRASHGHSADSSRQSGTRHAETSSRGQTASS 150
Query: 320 HDERKSTET*NFNRHH 273
H++ +S+ HH
Sbjct: 151 HEQARSSAGERHGSHH 166
>D45906-1|BAA08312.1| 638|Homo sapiens LIMK-2 protein.
Length = 638
Score = 30.3 bits (65), Expect = 5.7
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Frame = -3
Query: 611 QEIRSVISRPGQTMRICFRNTMKSLELEYFPTRIRLRTE-----HRHGGRRAEFKDHEYG 447
+E+ IS+ QT+++ + S L+ RL H H + K++ G
Sbjct: 218 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 277
Query: 446 TRHRRGIRRSET 411
T RR +RRS +
Sbjct: 278 TLRRRSLRRSNS 289
>CR456513-1|CAG30399.1| 638|Homo sapiens LIMK2 protein.
Length = 638
Score = 30.3 bits (65), Expect = 5.7
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Frame = -3
Query: 611 QEIRSVISRPGQTMRICFRNTMKSLELEYFPTRIRLRTE-----HRHGGRRAEFKDHEYG 447
+E+ IS+ QT+++ + S L+ RL H H + K++ G
Sbjct: 218 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 277
Query: 446 TRHRRGIRRSET 411
T RR +RRS +
Sbjct: 278 TLRRRSLRRSNS 289
>BC013051-1|AAH13051.1| 686|Homo sapiens LIM domain kinase 2
protein.
Length = 686
Score = 30.3 bits (65), Expect = 5.7
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Frame = -3
Query: 611 QEIRSVISRPGQTMRICFRNTMKSLELEYFPTRIRLRTE-----HRHGGRRAEFKDHEYG 447
+E+ IS+ QT+++ + S L+ RL H H + K++ G
Sbjct: 197 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 256
Query: 446 TRHRRGIRRSET 411
T RR +RRS +
Sbjct: 257 TLRRRSLRRSNS 268
>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
Length = 4061
Score = 30.3 bits (65), Expect = 5.7
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 446 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 273
TR R+G R + + +H+A+ Q R G RG + H E + + HH
Sbjct: 2759 TRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 2816
Score = 29.9 bits (64), Expect = 7.5
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 446 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 273
TR R+G R + + +H+A+ Q R G RG + H E + + HH
Sbjct: 3083 TRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 3140
>AC002073-3|AAB54055.1| 733|Homo sapiens Lim kinase protein.
Length = 733
Score = 30.3 bits (65), Expect = 5.7
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Frame = -3
Query: 611 QEIRSVISRPGQTMRICFRNTMKSLELEYFPTRIRLRTE-----HRHGGRRAEFKDHEYG 447
+E+ IS+ QT+++ + S L+ RL H H + K++ G
Sbjct: 197 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 256
Query: 446 TRHRRGIRRSET 411
T RR +RRS +
Sbjct: 257 TLRRRSLRRSNS 268
>AC002073-2|AAB54056.1| 638|Homo sapiens Lim Kinase protein.
Length = 638
Score = 30.3 bits (65), Expect = 5.7
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Frame = -3
Query: 611 QEIRSVISRPGQTMRICFRNTMKSLELEYFPTRIRLRTE-----HRHGGRRAEFKDHEYG 447
+E+ IS+ QT+++ + S L+ RL H H + K++ G
Sbjct: 218 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 277
Query: 446 TRHRRGIRRSET 411
T RR +RRS +
Sbjct: 278 TLRRRSLRRSNS 289
>AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin
variant protein.
Length = 583
Score = 30.3 bits (65), Expect = 5.7
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 446 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 273
TR R+G R + + +H+A+ Q R G RG + H E + + HH
Sbjct: 275 TRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 332
>X99717-1|CAA68053.1| 754|Homo sapiens SRcyp protein protein.
Length = 754
Score = 29.9 bits (64), Expect = 7.5
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)
Frame = -3
Query: 515 RIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ--------SQSNTR 360
R+R RT R R E+ + RRG RS R P + ++ S+S+ R
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 633
Query: 359 F*RGQQRGCDKWEHDERKST 300
Q R DK+ + E KS+
Sbjct: 634 E-ESQSRNKDKYRNQESKSS 652
>U40763-1|AAB40347.1| 754|Homo sapiens CARS-Cyp protein.
Length = 754
Score = 29.9 bits (64), Expect = 7.5
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)
Frame = -3
Query: 515 RIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ--------SQSNTR 360
R+R RT R R E+ + RRG RS R P + ++ S+S+ R
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 633
Query: 359 F*RGQQRGCDKWEHDERKST 300
Q R DK+ + E KS+
Sbjct: 634 E-ESQSRNKDKYRNQESKSS 652
>BC111693-1|AAI11694.1| 739|Homo sapiens PPIG protein protein.
Length = 739
Score = 29.9 bits (64), Expect = 7.5
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)
Frame = -3
Query: 515 RIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ--------SQSNTR 360
R+R RT R R E+ + RRG RS R P + ++ S+S+ R
Sbjct: 559 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 618
Query: 359 F*RGQQRGCDKWEHDERKST 300
Q R DK+ + E KS+
Sbjct: 619 E-ESQSRNKDKYRNQESKSS 637
>AC016772-2|AAY24233.1| 571|Homo sapiens unknown protein.
Length = 571
Score = 29.9 bits (64), Expect = 7.5
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)
Frame = -3
Query: 515 RIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ--------SQSNTR 360
R+R RT R R E+ + RRG RS R P + ++ S+S+ R
Sbjct: 391 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 450
Query: 359 F*RGQQRGCDKWEHDERKST 300
Q R DK+ + E KS+
Sbjct: 451 E-ESQSRNKDKYRNQESKSS 469
>M60499-1|AAA63246.1| 465|Homo sapiens profilaggrin protein.
Length = 465
Score = 29.5 bits (63), Expect = 9.9
Identities = 15/58 (25%), Positives = 25/58 (43%)
Frame = -3
Query: 446 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 273
T R+G + + +H+A+ + Q R G RG + H E+ T + HH
Sbjct: 267 TGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRTGHSGSHH 324
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 62,136,642
Number of Sequences: 237096
Number of extensions: 963510
Number of successful extensions: 2417
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 2329
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2417
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6635341780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -