Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-5633
(382 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U49356-1|AAA90924.1| 2285|Homo sapiens DNA polymerase epsilon ca... 93 4e-19
BC087613-1|AAH87613.1| 797|Homo sapiens POLE protein protein. 93 4e-19
BC021559-1|AAH21559.1| 370|Homo sapiens POLE protein protein. 93 4e-19
BC007599-1|AAH07599.1| 797|Homo sapiens Unknown (protein for IM... 93 4e-19
AY273166-1|AAP12650.1| 2265|Homo sapiens polymerase (DNA directe... 93 4e-19
AK025087-1|BAB15063.1| 370|Homo sapiens protein ( Homo sapiens ... 93 4e-19
S60080-1|AAA15448.1| 2257|Homo sapiens DNA polymerase epsilon ca... 92 5e-19
L09561-1|AAC19148.1| 2286|Homo sapiens DNA polymerase epsilon, c... 92 5e-19
AF127975-3|AAD44692.1| 2243|Homo sapiens DNA polymerase epsilon ... 92 5e-19
AF127975-2|AAD44691.1| 2286|Homo sapiens DNA polymerase epsilon ... 92 5e-19
AF127975-1|AAD44690.1| 2297|Homo sapiens DNA polymerase epsilon ... 92 5e-19
AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein. 29 3.8
X06745-1|CAA29920.1| 1462|Homo sapiens protein ( Human mRNA for ... 29 5.0
AY275833-1|AAP13534.1| 1462|Homo sapiens polymerase (DNA directe... 29 5.0
>U49356-1|AAA90924.1| 2285|Homo sapiens DNA polymerase epsilon
catalytic subunit protein.
Length = 2285
Score = 92.7 bits (220), Expect = 4e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2166 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2225
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2226 VKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHY 2264
>BC087613-1|AAH87613.1| 797|Homo sapiens POLE protein protein.
Length = 797
Score = 92.7 bits (220), Expect = 4e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 678 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 737
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 738 VKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHY 776
>BC021559-1|AAH21559.1| 370|Homo sapiens POLE protein protein.
Length = 370
Score = 92.7 bits (220), Expect = 4e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 251 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 310
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 311 VKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHY 349
>BC007599-1|AAH07599.1| 797|Homo sapiens Unknown (protein for
IMAGE:3347229) protein.
Length = 797
Score = 92.7 bits (220), Expect = 4e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 678 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 737
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 738 VKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHY 776
>AY273166-1|AAP12650.1| 2265|Homo sapiens polymerase (DNA directed),
epsilon protein.
Length = 2265
Score = 92.7 bits (220), Expect = 4e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2146 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2205
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2206 VKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHY 2244
>AK025087-1|BAB15063.1| 370|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21434 fis, clone COL04242. ).
Length = 370
Score = 92.7 bits (220), Expect = 4e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 251 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 310
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 311 VKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHY 349
>S60080-1|AAA15448.1| 2257|Homo sapiens DNA polymerase epsilon
catalytic subunit protein.
Length = 2257
Score = 92.3 bits (219), Expect = 5e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2138 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2197
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2198 VKETSMPVYCTCAGDFALTIHTQVFMEQIGIFRNIAQHY 2236
>L09561-1|AAC19148.1| 2286|Homo sapiens DNA polymerase epsilon,
catalytic polypeptide protein.
Length = 2286
Score = 92.3 bits (219), Expect = 5e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2167 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2226
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2227 VKETSMPVYCTCAGDFALTIHTQVFMEQIGIFRNIAQHY 2265
>AF127975-3|AAD44692.1| 2243|Homo sapiens DNA polymerase epsilon
catalytic subunit protein isoform c protein.
Length = 2243
Score = 92.3 bits (219), Expect = 5e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2124 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2183
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2184 VKETSMPVYCTCAGDFALTIHTQVFMEQIGIFRNIAQHY 2222
>AF127975-2|AAD44691.1| 2286|Homo sapiens DNA polymerase epsilon
catalytic subunit protein isoform b protein.
Length = 2286
Score = 92.3 bits (219), Expect = 5e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2167 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2226
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2227 VKETSMPVYCTCAGDFALTIHTQVFMEQIGIFRNIAQHY 2265
>AF127975-1|AAD44690.1| 2297|Homo sapiens DNA polymerase epsilon
catalytic subunit protein isoform a protein.
Length = 2297
Score = 92.3 bits (219), Expect = 5e-19
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = -2
Query: 381 LDLCRDA---RDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRPMAYTLQDLICSRCRQ 211
LDLC+D+ D P LC C YD+ IE L+E + K+ MA+TLQDL+C +CR
Sbjct: 2178 LDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRG 2237
Query: 210 VKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTITEYY 94
VK ++ V C CAGDF+L + +Q+ F+ I ++Y
Sbjct: 2238 VKETSMPVYCTCAGDFALTIHTQVFMEQIGIFRNIAQHY 2276
>AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein.
Length = 4464
Score = 29.5 bits (63), Expect = 3.8
Identities = 14/39 (35%), Positives = 23/39 (58%)
Frame = +1
Query: 157 QRKISSTITDHRQILTFYLATSATYKILQRIRHRTFVHR 273
Q +ISS +T++ +L YL T Y+ + I +F+HR
Sbjct: 975 QTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR 1013
>X06745-1|CAA29920.1| 1462|Homo sapiens protein ( Human mRNA for DNA
polymerase alpha-subunit. ).
Length = 1462
Score = 29.1 bits (62), Expect = 5.0
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 2/20 (10%)
Frame = -2
Query: 354 DTERPACLCPTCGT--AYDN 301
D ER C CPTCGT YDN
Sbjct: 1275 DCERFKCPCPTCGTENIYDN 1294
>AY275833-1|AAP13534.1| 1462|Homo sapiens polymerase (DNA directed),
alpha protein.
Length = 1462
Score = 29.1 bits (62), Expect = 5.0
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 2/20 (10%)
Frame = -2
Query: 354 DTERPACLCPTCGT--AYDN 301
D ER C CPTCGT YDN
Sbjct: 1275 DCERFKCPCPTCGTENIYDN 1294
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 53,630,249
Number of Sequences: 237096
Number of extensions: 1074724
Number of successful extensions: 5736
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5650
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5736
length of database: 76,859,062
effective HSP length: 82
effective length of database: 57,417,190
effective search space used: 2526356360
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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