Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-5273
(584 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 52 2e-06
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 52 2e-06
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 52 2e-06
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 52 2e-06
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 52 2e-06
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 52 2e-06
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 52 2e-06
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 52 2e-06
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 52 2e-06
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 52 2e-06
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 52 2e-06
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 52 2e-06
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 52 2e-06
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 52 2e-06
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 52 2e-06
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 52 2e-06
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 51 3e-06
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 51 3e-06
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 51 3e-06
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 51 3e-06
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 44 3e-04
M16764-1|AAA88099.1| 286|Homo sapiens pulmonary surfactant-asso... 33 0.98
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 32 1.7
M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary... 32 1.7
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 32 1.7
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 32 1.7
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 32 1.7
AY223815-1|AAP41103.1| 3997|Homo sapiens Cohen syndrome 1 protei... 29 9.1
AY223814-1|AAP41102.1| 4022|Homo sapiens Cohen syndrome 1 protei... 29 9.1
AJ608773-1|CAE75585.1| 3997|Homo sapiens VPS13B-2A protein protein. 29 9.1
AJ608772-1|CAE75584.1| 4022|Homo sapiens VPS13B-1A protein protein. 29 9.1
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 6 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 65
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 66 LSILLEEVSPELVCSMLHLC 85
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 106 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 165
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 166 VMDPSFVCLKIGAC 179
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 311 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 370
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 371 LSILLEEVSPELVCSMLHLC 390
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 411 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 470
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 471 VMDPSFVCLKIGAC 484
Score = 41.9 bits (94), Expect = 0.002
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 3/188 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSEIAIQMMM 257
Query: 195 S-DLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPA 371
D +P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 HMDQQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPA 297
Query: 372 SAAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDA 551
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +
Sbjct: 298 LELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKS 354
Query: 552 LQR*MQGV 575
L Q V
Sbjct: 355 LSEECQEV 362
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
Score = 41.1 bits (92), Expect = 0.003
Identities = 40/187 (21%), Positives = 81/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 312 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 371
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 372 LSILLEEVSPELVCSMLHLC 391
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 412 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 471
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 472 VMDPSFVCLKIGAC 485
Score = 41.5 bits (93), Expect = 0.002
Identities = 41/189 (21%), Positives = 81/189 (42%), Gaps = 4/189 (2%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSEIAIQMMM 257
Query: 195 --SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEP 368
D +P E C ++G C + P+ LV +K+A +K + P
Sbjct: 258 HMQDQQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIP 297
Query: 369 ASAAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPD 548
A V P+++ V A +S C C++ + + + + +TE ++ A + C LP
Sbjct: 298 ALELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPK 354
Query: 549 ALQR*MQGV 575
+L Q V
Sbjct: 355 SLSEECQEV 363
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 312 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 371
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 372 LSILLEEVSPELVCSMLHLC 391
Score = 45.6 bits (103), Expect = 1e-04
Identities = 42/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 --SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEP 368
D +P E C ++G C + P+ LV +K+A +K + P
Sbjct: 258 HMQDQQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIP 297
Query: 369 ASAAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPD 548
A V P+++ V A +S C C++ + + + + +TE ++ A + C LP
Sbjct: 298 ALELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPK 354
Query: 549 ALQR*MQGV 575
+L Q V
Sbjct: 355 SLSEECQEV 363
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 412 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 471
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 472 VMDPSFVCLKIGAC 485
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 LSILLEEVSPELVCSMLHLC 388
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
Score = 43.6 bits (98), Expect = 5e-04
Identities = 40/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C ++V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIRMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 315 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 374
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 375 LSILLEEVSPELVCSMLHLC 394
Score = 45.6 bits (103), Expect = 1e-04
Identities = 42/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 201 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 260
Query: 195 --SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEP 368
D +P E C ++G C + P+ LV +K+A +K + P
Sbjct: 261 HMQDQQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIP 300
Query: 369 ASAAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPD 548
A V P+++ V A +S C C++ + + + + +TE ++ A + C LP
Sbjct: 301 ALELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPK 357
Query: 549 ALQR*MQGV 575
+L Q V
Sbjct: 358 SLSEECQEV 366
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 415 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 474
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 475 VMDPSFVCLKIGAC 488
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 51.2 bits (117), Expect = 3e-06
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +3
Query: 15 VPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFL 191
V CE C +V+ L L++N++EL L+ +C EC+ L + Y P + L
Sbjct: 292 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 350
Query: 192 VSDLKPAETCKMIGICGN 245
V+ + P + CK I +CGN
Sbjct: 351 VAKITPEKVCKFIRLCGN 368
Score = 37.5 bits (83), Expect = 0.034
Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTG-KFKDECLHLAEQYYPVIYNFLVS 197
C C++L+ L + +T+ + +G C + +C H QY PV+ L
Sbjct: 396 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 455
Query: 198 DLKPAETCKMIGIC 239
+ P CK +G C
Sbjct: 456 MMDPVAVCKKVGAC 469
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 51.2 bits (117), Expect = 3e-06
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +3
Query: 15 VPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFL 191
V CE C +V+ L L++N++EL L+ +C EC+ L + Y P + L
Sbjct: 314 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 372
Query: 192 VSDLKPAETCKMIGICGN 245
V+ + P + CK I +CGN
Sbjct: 373 VAKITPEKVCKFIRLCGN 390
Score = 37.5 bits (83), Expect = 0.034
Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTG-KFKDECLHLAEQYYPVIYNFLVS 197
C C++L+ L + +T+ + +G C + +C H QY PV+ L
Sbjct: 418 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 477
Query: 198 DLKPAETCKMIGIC 239
+ P CK +G C
Sbjct: 478 MMDPVAVCKKVGAC 491
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 51.2 bits (117), Expect = 3e-06
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +3
Query: 15 VPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFL 191
V CE C +V+ L L++N++EL L+ +C EC+ L + Y P + L
Sbjct: 24 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 82
Query: 192 VSDLKPAETCKMIGICGN 245
V+ + P + CK I +CGN
Sbjct: 83 VAKITPEKVCKFIRLCGN 100
Score = 37.5 bits (83), Expect = 0.034
Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTG-KFKDECLHLAEQYYPVIYNFLVS 197
C C++L+ L + +T+ + +G C + +C H QY PV+ L
Sbjct: 128 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 187
Query: 198 DLKPAETCKMIGIC 239
+ P CK +G C
Sbjct: 188 MMDPVAVCKKVGAC 201
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 50.8 bits (116), Expect = 3e-06
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 ATDDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGK-FKDECLHLAEQYYPVI 179
A DV CE CE LVK + ++ N TE E +C + K +EC + + Y I
Sbjct: 309 AKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368
Query: 180 YNFLVSDLKPAETCKMIGIC 239
+ L+ ++ P C M+ +C
Sbjct: 369 PSILLEEVSPELVCSMLHLC 388
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELE-FYKVLQGLCKQTGK-FKDECLHLAEQYYPVIYNFLV 194
C+ C Q+V ++ + N+T ++ + ++ C + G D C + QY + ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 195 SDLKPAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKIARVPLAKQMEPAS 374
++P E C ++G C + P+ LV +K+A +K + PA
Sbjct: 258 H-MQPKEICALVGFCDEVKEMPMQTLV----------------PAKVA----SKNVIPAL 296
Query: 375 AAVSVLPLERMFVAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAIQEACDALPDAL 554
V P+++ V A +S C C++ + + + + +TE ++ A + C LP +L
Sbjct: 297 ELVE--PIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
Query: 555 QR*MQGV 575
Q V
Sbjct: 354 SEECQEV 360
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 469 VMDPSFVCLKIGAC 482
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 21 CEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK-QTGKFKDECLHLAEQYYPVIYNFLVS 197
CE C++LV +L L N+T+ E L+ C ++ +C +Y PV+ LV
Sbjct: 125 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 184
Query: 198 DLKPAETCKMIGIC 239
+ P+ C IG C
Sbjct: 185 VMDPSFVCLKIGAC 198
>M16764-1|AAA88099.1| 286|Homo sapiens pulmonary
surfactant-associated proteolipid protein protein.
Length = 286
Score = 32.7 bits (71), Expect = 0.98
Identities = 13/61 (21%), Positives = 29/61 (47%)
Frame = +3
Query: 72 NTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLKPAETCKMIGICGNLT 251
N++E + + C + +++C EQ+ P + + TC+ +G+CG ++
Sbjct: 216 NSSEQAILQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMS 275
Query: 252 S 254
S
Sbjct: 276 S 276
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 31.9 bits (69), Expect = 1.7
Identities = 13/61 (21%), Positives = 29/61 (47%)
Frame = +3
Query: 72 NTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLKPAETCKMIGICGNLT 251
N++E + + C + +++C EQ+ P + + TC+ +G+CG ++
Sbjct: 311 NSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMS 370
Query: 252 S 254
S
Sbjct: 371 S 371
Score = 29.5 bits (63), Expect = 9.1
Identities = 17/86 (19%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Frame = +3
Query: 9 DDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK--QTGKFKDECLHLAEQYYPVIY 182
DD+ C+ CE +V L + + K L+ C +C + + Y+P++
Sbjct: 66 DDL-CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVI 124
Query: 183 NFLVSDLKPAETCKMIGICGNLTSAP 260
++ + + C +G+C + P
Sbjct: 125 DYFQNQIDSNGICMHLGLCKSRQPEP 150
>M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary
surfactant apoprotein 18 (SP 18) mRNA, 3' end. ).
Length = 243
Score = 31.9 bits (69), Expect = 1.7
Identities = 13/61 (21%), Positives = 29/61 (47%)
Frame = +3
Query: 72 NTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLKPAETCKMIGICGNLT 251
N++E + + C + +++C EQ+ P + + TC+ +G+CG ++
Sbjct: 173 NSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMS 232
Query: 252 S 254
S
Sbjct: 233 S 233
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 31.9 bits (69), Expect = 1.7
Identities = 13/61 (21%), Positives = 29/61 (47%)
Frame = +3
Query: 72 NTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLKPAETCKMIGICGNLT 251
N++E + + C + +++C EQ+ P + + TC+ +G+CG ++
Sbjct: 311 NSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMS 370
Query: 252 S 254
S
Sbjct: 371 S 371
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 31.9 bits (69), Expect = 1.7
Identities = 13/61 (21%), Positives = 29/61 (47%)
Frame = +3
Query: 72 NTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLKPAETCKMIGICGNLT 251
N++E + + C + +++C EQ+ P + + TC+ +G+CG ++
Sbjct: 311 NSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMS 370
Query: 252 S 254
S
Sbjct: 371 S 371
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 31.9 bits (69), Expect = 1.7
Identities = 13/61 (21%), Positives = 29/61 (47%)
Frame = +3
Query: 72 NTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLKPAETCKMIGICGNLT 251
N++E + + C + +++C EQ+ P + + TC+ +G+CG ++
Sbjct: 311 NSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMS 370
Query: 252 S 254
S
Sbjct: 371 S 371
Score = 29.5 bits (63), Expect = 9.1
Identities = 17/86 (19%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Frame = +3
Query: 9 DDVPCEFCEQLVKHLRDVLVANTTELEFYKVLQGLCK--QTGKFKDECLHLAEQYYPVIY 182
DD+ C+ CE +V L + + K L+ C +C + + Y+P++
Sbjct: 66 DDL-CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVI 124
Query: 183 NFLVSDLKPAETCKMIGICGNLTSAP 260
++ + + C +G+C + P
Sbjct: 125 DYFQNQIDSNGICMHLGLCKSRQPEP 150
>AY223815-1|AAP41103.1| 3997|Homo sapiens Cohen syndrome 1 protein
splice variant 1 protein.
Length = 3997
Score = 29.5 bits (63), Expect = 9.1
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Frame = +3
Query: 27 FCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLK 206
+ + + K++R L + F+K+ +GL + F E L A+ + V+Y L++ +
Sbjct: 1428 YTKAVTKNVRHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIA 1487
Query: 207 PAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKI-ARVPLAKQMEPASAA 380
K+ +P P+ L + P LI S I +P ++M+P A
Sbjct: 1488 SIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLP-LIYVNTSVIRIFIPKTEEMQPTVEA 1545
>AY223814-1|AAP41102.1| 4022|Homo sapiens Cohen syndrome 1 protein
protein.
Length = 4022
Score = 29.5 bits (63), Expect = 9.1
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Frame = +3
Query: 27 FCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLK 206
+ + + K++R L + F+K+ +GL + F E L A+ + V+Y L++ +
Sbjct: 1453 YTKAVTKNVRHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIA 1512
Query: 207 PAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKI-ARVPLAKQMEPASAA 380
K+ +P P+ L + P LI S I +P ++M+P A
Sbjct: 1513 SIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLP-LIYVNTSVIRIFIPKTEEMQPTVEA 1570
>AJ608773-1|CAE75585.1| 3997|Homo sapiens VPS13B-2A protein protein.
Length = 3997
Score = 29.5 bits (63), Expect = 9.1
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Frame = +3
Query: 27 FCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLK 206
+ + + K++R L + F+K+ +GL + F E L A+ + V+Y L++ +
Sbjct: 1428 YTKAVTKNVRHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIA 1487
Query: 207 PAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKI-ARVPLAKQMEPASAA 380
K+ +P P+ L + P LI S I +P ++M+P A
Sbjct: 1488 SIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLP-LIYVNTSVIRIFIPKTEEMQPTVEA 1545
>AJ608772-1|CAE75584.1| 4022|Homo sapiens VPS13B-1A protein protein.
Length = 4022
Score = 29.5 bits (63), Expect = 9.1
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Frame = +3
Query: 27 FCEQLVKHLRDVLVANTTELEFYKVLQGLCKQTGKFKDECLHLAEQYYPVIYNFLVSDLK 206
+ + + K++R L + F+K+ +GL + F E L A+ + V+Y L++ +
Sbjct: 1453 YTKAVTKNVRHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIA 1512
Query: 207 PAETCKMIGICGNLTSAPISPLVARELVVKVQPKLIGAEESKI-ARVPLAKQMEPASAA 380
K+ +P P+ L + P LI S I +P ++M+P A
Sbjct: 1513 SIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLP-LIYVNTSVIRIFIPKTEEMQPTVEA 1570
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,929,757
Number of Sequences: 237096
Number of extensions: 1397404
Number of successful extensions: 5059
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 4693
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5020
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6098631048
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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