Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-5095
(659 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X71125-1|CAA50438.1| 361|Homo sapiens glutaminyl-peptide cyclot... 107 3e-23
BC047756-1|AAH47756.1| 361|Homo sapiens glutaminyl-peptide cycl... 107 3e-23
BC036721-1|AAH36721.1| 361|Homo sapiens glutaminyl-peptide cycl... 107 3e-23
AC007391-1|AAY14804.1| 361|Homo sapiens unknown protein. 107 3e-23
X67731-1|CAA47961.1| 251|Homo sapiens glutaminyl-peptide cyclot... 96 9e-20
AK222636-1|BAD96356.1| 382|Homo sapiens glutaminyl-peptide cycl... 92 1e-18
AK172764-1|BAD18747.1| 382|Homo sapiens protein ( Homo sapiens ... 92 1e-18
AK000091-1|BAA90938.1| 382|Homo sapiens protein ( Homo sapiens ... 92 1e-18
>X71125-1|CAA50438.1| 361|Homo sapiens glutaminyl-peptide
cyclotransferase protein.
Length = 361
Score = 107 bits (257), Expect = 3e-23
Identities = 60/146 (41%), Positives = 86/146 (58%), Gaps = 6/146 (4%)
Frame = +3
Query: 219 QEKNFHEPLDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 395
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 396 M--GWSVTENVFPDHTPVFGTLNFKNIIAELNPNADRYLVLACHYDSKYTT---EHVFVG 560
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY + VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 561 ATDSAVPCAMLLNLAKMMKKQLERLK 638
ATDSAVPCAM+L LA+ + K+L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>BC047756-1|AAH47756.1| 361|Homo sapiens glutaminyl-peptide
cyclotransferase (glutaminyl cyclase) protein.
Length = 361
Score = 107 bits (257), Expect = 3e-23
Identities = 60/146 (41%), Positives = 86/146 (58%), Gaps = 6/146 (4%)
Frame = +3
Query: 219 QEKNFHEPLDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 395
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 396 M--GWSVTENVFPDHTPVFGTLNFKNIIAELNPNADRYLVLACHYDSKYTT---EHVFVG 560
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY + VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 561 ATDSAVPCAMLLNLAKMMKKQLERLK 638
ATDSAVPCAM+L LA+ + K+L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>BC036721-1|AAH36721.1| 361|Homo sapiens glutaminyl-peptide
cyclotransferase (glutaminyl cyclase) protein.
Length = 361
Score = 107 bits (257), Expect = 3e-23
Identities = 60/146 (41%), Positives = 86/146 (58%), Gaps = 6/146 (4%)
Frame = +3
Query: 219 QEKNFHEPLDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 395
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 396 M--GWSVTENVFPDHTPVFGTLNFKNIIAELNPNADRYLVLACHYDSKYTT---EHVFVG 560
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY + VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 561 ATDSAVPCAMLLNLAKMMKKQLERLK 638
ATDSAVPCAM+L LA+ + K+L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>AC007391-1|AAY14804.1| 361|Homo sapiens unknown protein.
Length = 361
Score = 107 bits (257), Expect = 3e-23
Identities = 60/146 (41%), Positives = 86/146 (58%), Gaps = 6/146 (4%)
Frame = +3
Query: 219 QEKNFHEPLDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 395
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 396 M--GWSVTENVFPDHTPVFGTLNFKNIIAELNPNADRYLVLACHYDSKYTT---EHVFVG 560
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY + VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 561 ATDSAVPCAMLLNLAKMMKKQLERLK 638
ATDSAVPCAM+L LA+ + K+L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>X67731-1|CAA47961.1| 251|Homo sapiens glutaminyl-peptide
cyclotransferase protein.
Length = 251
Score = 96.3 bits (229), Expect = 9e-20
Identities = 53/114 (46%), Positives = 70/114 (61%), Gaps = 5/114 (4%)
Frame = +3
Query: 312 LNEILIPRVVGTPNHEKVGNYIANEMRTM--GWSVTENVFPDHTPVFGTLNFKNIIAELN 485
L +LI R G+P +I ++ + W + + F TP +G +F NII+ LN
Sbjct: 4 LRPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTP-YGYRSFSNIISTLN 62
Query: 486 PNADRYLVLACHYDSKYTT---EHVFVGATDSAVPCAMLLNLAKMMKKQLERLK 638
P A R+LVLACHYDSKY + VFVGATDSAVPCAM+L LA+ + K+L LK
Sbjct: 63 PTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLSLK 116
>AK222636-1|BAD96356.1| 382|Homo sapiens glutaminyl-peptide
cyclotransferase-like variant protein.
Length = 382
Score = 92.3 bits (219), Expect = 1e-18
Identities = 51/128 (39%), Positives = 74/128 (57%), Gaps = 4/128 (3%)
Frame = +3
Query: 267 KAIANLSDLDHFKAVLNEILIPRVVGTPNHEKVGNYIANEMR--TMGWSVTENVFPDHTP 440
+ + L + L +L+ R G+P + +V ++ +R T GW V + F TP
Sbjct: 83 RVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTP 142
Query: 441 VFGTLNFKNIIAELNPNADRYLVLACHYDSKY--TTEHVFVGATDSAVPCAMLLNLAKMM 614
+ G ++F N++A L+P A R+L LACHYDSK FVGATDSAVPCA+LL LA+ +
Sbjct: 143 L-GPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
Query: 615 KKQLERLK 638
+L R K
Sbjct: 202 DLELSRAK 209
>AK172764-1|BAD18747.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ23925 fis, clone COL03589. ).
Length = 382
Score = 92.3 bits (219), Expect = 1e-18
Identities = 51/128 (39%), Positives = 74/128 (57%), Gaps = 4/128 (3%)
Frame = +3
Query: 267 KAIANLSDLDHFKAVLNEILIPRVVGTPNHEKVGNYIANEMR--TMGWSVTENVFPDHTP 440
+ + L + L +L+ R G+P + +V ++ +R T GW V + F TP
Sbjct: 83 RVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTP 142
Query: 441 VFGTLNFKNIIAELNPNADRYLVLACHYDSKY--TTEHVFVGATDSAVPCAMLLNLAKMM 614
+ G ++F N++A L+P A R+L LACHYDSK FVGATDSAVPCA+LL LA+ +
Sbjct: 143 L-GPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
Query: 615 KKQLERLK 638
+L R K
Sbjct: 202 DLELSRAK 209
>AK000091-1|BAA90938.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ20084 fis, clone COL03526. ).
Length = 382
Score = 92.3 bits (219), Expect = 1e-18
Identities = 51/128 (39%), Positives = 74/128 (57%), Gaps = 4/128 (3%)
Frame = +3
Query: 267 KAIANLSDLDHFKAVLNEILIPRVVGTPNHEKVGNYIANEMR--TMGWSVTENVFPDHTP 440
+ + L + L +L+ R G+P + +V ++ +R T GW V + F TP
Sbjct: 83 RVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTP 142
Query: 441 VFGTLNFKNIIAELNPNADRYLVLACHYDSKY--TTEHVFVGATDSAVPCAMLLNLAKMM 614
+ G ++F N++A L+P A R+L LACHYDSK FVGATDSAVPCA+LL LA+ +
Sbjct: 143 L-GPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
Query: 615 KKQLERLK 638
+L R K
Sbjct: 202 DLELSRAK 209
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 86,346,931
Number of Sequences: 237096
Number of extensions: 1648721
Number of successful extensions: 3697
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3495
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3685
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7422585720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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