Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-4972
(738 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 77 5e-14
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 77 5e-14
BC067812-1|AAH67812.1| 526|Homo sapiens cyclin L1 protein. 32 1.9
BC007081-1|AAH07081.1| 526|Homo sapiens cyclin L1 protein. 32 1.9
AY358663-1|AAQ89026.1| 299|Homo sapiens CCNL1 protein. 32 1.9
AF180920-1|AAD53184.1| 526|Homo sapiens cyclin L ania-6a protein. 32 1.9
X99717-1|CAA68053.1| 754|Homo sapiens SRcyp protein protein. 31 3.3
U40763-1|AAB40347.1| 754|Homo sapiens CARS-Cyp protein. 31 3.3
BC111693-1|AAI11694.1| 739|Homo sapiens PPIG protein protein. 31 3.3
AC016772-2|AAY24233.1| 571|Homo sapiens unknown protein. 31 3.3
BC040341-1|AAH40341.1| 1063|Homo sapiens KIAA1618 protein. 31 5.7
BC036891-1|AAH36891.1| 1063|Homo sapiens KIAA1618 protein. 31 5.7
M96943-1|AAA36487.1| 1218|Homo sapiens profilaggrin protein. 30 7.5
M60494-1|AAA63244.1| 990|Homo sapiens profilaggrin protein. 30 7.5
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein. 30 7.5
AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin va... 30 7.5
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 77.4 bits (182), Expect = 5e-14
Identities = 32/62 (51%), Positives = 46/62 (74%)
Frame = -1
Query: 696 PEAAFFARSYIPSKICEVVKMWRESVGATNKKSGQSLADPVNYENLFPEYNESLELEYFQ 517
PEAAF AR+Y+PS++ VVK+WRE++ N+K+ +SLADP YENLFP E+ +E +
Sbjct: 752 PEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWV 811
Query: 516 RE 511
+E
Sbjct: 812 KE 813
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 77.4 bits (182), Expect = 5e-14
Identities = 32/62 (51%), Positives = 46/62 (74%)
Frame = -1
Query: 696 PEAAFFARSYIPSKICEVVKMWRESVGATNKKSGQSLADPVNYENLFPEYNESLELEYFQ 517
PEAAF AR+Y+PS++ VVK+WRE++ N+K+ +SLADP YENLFP E+ +E +
Sbjct: 752 PEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWV 811
Query: 516 RE 511
+E
Sbjct: 812 KE 813
>BC067812-1|AAH67812.1| 526|Homo sapiens cyclin L1 protein.
Length = 526
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 502 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 329
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 495
Query: 328 KWEHDERKSTET*NFNRHHGGDRTG 254
+ + +S E + ++HHGG R+G
Sbjct: 496 RDRRERSRSFERSHKSKHHGGSRSG 520
>BC007081-1|AAH07081.1| 526|Homo sapiens cyclin L1 protein.
Length = 526
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 502 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 329
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 495
Query: 328 KWEHDERKSTET*NFNRHHGGDRTG 254
+ + +S E + ++HHGG R+G
Sbjct: 496 RDRRERSRSFERSHKSKHHGGSRSG 520
>AY358663-1|AAQ89026.1| 299|Homo sapiens CCNL1 protein.
Length = 299
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 502 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 329
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 211 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 268
Query: 328 KWEHDERKSTET*NFNRHHGGDRTG 254
+ + +S E + ++HHGG R+G
Sbjct: 269 RDRRERSRSFERSHKSKHHGGSRSG 293
>AF180920-1|AAD53184.1| 526|Homo sapiens cyclin L ania-6a protein.
Length = 526
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -3
Query: 502 RTEHRHGGR--RAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCD 329
R H HG +A+ + + +R G +R ++ Q + S + + +RG
Sbjct: 438 RRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKK--HRHERGHH 495
Query: 328 KWEHDERKSTET*NFNRHHGGDRTG 254
+ + +S E + ++HHGG R+G
Sbjct: 496 RDRRERSRSFERSHKSKHHGGSRSG 520
>X99717-1|CAA68053.1| 754|Homo sapiens SRcyp protein protein.
Length = 754
Score = 31.5 bits (68), Expect = 3.3
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Frame = -3
Query: 535 RARILPTRIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ------- 377
R+R R+R RT R R E+ + RRG RS R P + ++
Sbjct: 567 RSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR 626
Query: 376 -SQSNTRF*RGQQRGCDKWEHDERKST 299
S+S+ R Q R DK+ + E KS+
Sbjct: 627 DSRSSERE-ESQSRNKDKYRNQESKSS 652
>U40763-1|AAB40347.1| 754|Homo sapiens CARS-Cyp protein.
Length = 754
Score = 31.5 bits (68), Expect = 3.3
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Frame = -3
Query: 535 RARILPTRIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ------- 377
R+R R+R RT R R E+ + RRG RS R P + ++
Sbjct: 567 RSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR 626
Query: 376 -SQSNTRF*RGQQRGCDKWEHDERKST 299
S+S+ R Q R DK+ + E KS+
Sbjct: 627 DSRSSERE-ESQSRNKDKYRNQESKSS 652
>BC111693-1|AAI11694.1| 739|Homo sapiens PPIG protein protein.
Length = 739
Score = 31.5 bits (68), Expect = 3.3
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Frame = -3
Query: 535 RARILPTRIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ------- 377
R+R R+R RT R R E+ + RRG RS R P + ++
Sbjct: 552 RSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR 611
Query: 376 -SQSNTRF*RGQQRGCDKWEHDERKST 299
S+S+ R Q R DK+ + E KS+
Sbjct: 612 DSRSSERE-ESQSRNKDKYRNQESKSS 637
>AC016772-2|AAY24233.1| 571|Homo sapiens unknown protein.
Length = 571
Score = 31.5 bits (68), Expect = 3.3
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Frame = -3
Query: 535 RARILPTRIRLRTEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQ------- 377
R+R R+R RT R R E+ + RRG RS R P + ++
Sbjct: 384 RSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR 443
Query: 376 -SQSNTRF*RGQQRGCDKWEHDERKST 299
S+S+ R Q R DK+ + E KS+
Sbjct: 444 DSRSSERE-ESQSRNKDKYRNQESKSS 469
>BC040341-1|AAH40341.1| 1063|Homo sapiens KIAA1618 protein.
Length = 1063
Score = 30.7 bits (66), Expect = 5.7
Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Frame = -1
Query: 612 TNKKSGQSLADPVNYENLFPEYN-----ESLELEYFQREFGYEQSTAMEAV-EPNSKITN 451
T+ G S + E L PE EL+ +++ G STA++AV EP + +
Sbjct: 225 TSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASTAVDAVAEPANAVKG 284
Query: 450 TERDIAAEYAEAKRRGPLNIPPLLNHNQIQDS----EGDSREDATNGNTTSESQQKRK 289
+++ E + ++ P PP H Q ++ E + E+ N E + +K
Sbjct: 285 AGKEM-KEKTQRMKQPPATTPPFKTHCQEAETKTKDETAAAEEKVGKNEQGEPEDLKK 341
>BC036891-1|AAH36891.1| 1063|Homo sapiens KIAA1618 protein.
Length = 1063
Score = 30.7 bits (66), Expect = 5.7
Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Frame = -1
Query: 612 TNKKSGQSLADPVNYENLFPEYN-----ESLELEYFQREFGYEQSTAMEAV-EPNSKITN 451
T+ G S + E L PE EL+ +++ G STA++AV EP + +
Sbjct: 225 TSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASTAVDAVAEPANAVKG 284
Query: 450 TERDIAAEYAEAKRRGPLNIPPLLNHNQIQDS----EGDSREDATNGNTTSESQQKRK 289
+++ E + ++ P PP H Q ++ E + E+ N E + +K
Sbjct: 285 AGKEM-KEKTQRMKQPPATTPPFKTHCQEAETKTKDETAAAEEKVGKNEQGEPEDLKK 341
>M96943-1|AAA36487.1| 1218|Homo sapiens profilaggrin protein.
Length = 1218
Score = 30.3 bits (65), Expect = 7.5
Identities = 15/58 (25%), Positives = 26/58 (44%)
Frame = -3
Query: 445 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 272
TR R+G + + +H+A+ + Q R G RG + H E+ + + HH
Sbjct: 813 TRRRQGSHHDQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHH 870
Score = 29.9 bits (64), Expect = 10.0
Identities = 20/76 (26%), Positives = 32/76 (42%)
Frame = -3
Query: 499 TEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWE 320
+ + HG + +D G+RH R E + H+A + QS TR RG
Sbjct: 318 SRNHHGSAWEQSRD---GSRHPRS--HDEDRASHGHSADSSRQSGTRHAETSSRGQTASS 372
Query: 319 HDERKSTET*NFNRHH 272
H++ +S+ HH
Sbjct: 373 HEQARSSAGERHGSHH 388
>M60494-1|AAA63244.1| 990|Homo sapiens profilaggrin protein.
Length = 990
Score = 30.3 bits (65), Expect = 7.5
Identities = 15/58 (25%), Positives = 26/58 (44%)
Frame = -3
Query: 445 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 272
TR R+G + + +H+A+ + Q R G RG + H E+ + + HH
Sbjct: 591 TRRRQGSHHDQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHH 648
Score = 29.9 bits (64), Expect = 10.0
Identities = 20/76 (26%), Positives = 32/76 (42%)
Frame = -3
Query: 499 TEHRHGGRRAEFKDHEYGTRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWE 320
+ + HG + +D G+RH R E + H+A + QS TR RG
Sbjct: 96 SRNHHGSAWEQSRD---GSRHPRS--HDEDRASHGHSADSSRQSGTRHAETSSRGQTASS 150
Query: 319 HDERKSTET*NFNRHH 272
H++ +S+ HH
Sbjct: 151 HEQARSSAGERHGSHH 166
>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
Length = 4061
Score = 30.3 bits (65), Expect = 7.5
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 445 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 272
TR R+G R + + +H+A+ Q R G RG + H E + + HH
Sbjct: 2759 TRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 2816
Score = 29.9 bits (64), Expect = 10.0
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 445 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 272
TR R+G R + + +H+A+ Q R G RG + H E + + HH
Sbjct: 3083 TRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 3140
>AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin
variant protein.
Length = 583
Score = 30.3 bits (65), Expect = 7.5
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 445 TRHRRGIRRSETTRAPQHTAATQSQSNTRF*RGQQRGCDKWEHDERKSTET*NFNRHH 272
TR R+G R + + +H+A+ Q R G RG + H E + + HH
Sbjct: 275 TRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 332
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 81,696,364
Number of Sequences: 237096
Number of extensions: 1405214
Number of successful extensions: 2951
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 2830
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2951
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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