Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-4048
(593 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 40 0.005
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 40 0.005
BC070050-1|AAH70050.1| 1022|Homo sapiens SRRM2 protein protein. 31 3.1
AF201422-1|AAF21439.1| 2296|Homo sapiens splicing coactivator su... 31 3.1
AB016092-1|BAA83718.1| 2752|Homo sapiens RNA binding protein pro... 31 3.1
AB016088-1|BAA83714.1| 956|Homo sapiens RNA binding protein pro... 31 3.1
AB016087-1|BAA83713.1| 1262|Homo sapiens RNA binding protein pro... 31 3.1
AB002322-1|BAA20782.3| 2800|Homo sapiens KIAA0324 protein protein. 31 3.1
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 30 5.4
BC035621-1|AAH35621.1| 893|Homo sapiens chromosome 12 open read... 29 9.4
BC027450-1|AAH27450.1| 469|Homo sapiens SETD1A protein protein. 29 9.4
AB002337-1|BAA20797.2| 1709|Homo sapiens KIAA0339 protein protein. 29 9.4
>L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein.
Length = 1898
Score = 40.3 bits (90), Expect = 0.005
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
Frame = -1
Query: 563 RQPQVQRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLE-HREQSMSRKMVIHERLWTSK 387
R+ Q++R+ Q R QQ R QLR R + +RR + REQ R HE+ +
Sbjct: 410 REQQLRREQQLRRE---QQLRREQQLR--REQQLRREQQLRREQEEERHEQKHEQERREQ 464
Query: 386 KILRKQLEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHR 207
++ R+Q E+ W + E + +R + R L + ++ + +E++ R +Q R
Sbjct: 465 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER---REQQER 521
Query: 206 RQRCGHRERCELSKKRPKTQ 147
R++ RE+ E ++R K Q
Sbjct: 522 REQQLRREQEERREQRLKRQ 541
Score = 30.7 bits (66), Expect = 4.1
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 5/164 (3%)
Frame = -1
Query: 548 QRKLQRERSP*RQQARSTSQLRV*RGRSMRRWL--EHREQSMSRKMVIHERLWTSKKILR 375
+++L+RE+ R+Q Q R + +RR E REQ + R+ R ++
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQEEERREQQLRR--E 393
Query: 374 KQLEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQHKRRQE---QQWS**RLEQHRR 204
+QL + + E Q +R R L + QQ +R Q+ +Q E+ R
Sbjct: 394 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 453
Query: 203 QRCGHRERCELSKKRPKTQLD*WF*LPQQEPR*CGCKPREQLPR 72
++ +ER E KR + + W ++ R + ++QL R
Sbjct: 454 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 497
Score = 30.7 bits (66), Expect = 4.1
Identities = 29/137 (21%), Positives = 56/137 (40%), Gaps = 2/137 (1%)
Frame = -1
Query: 548 QRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSRKMVIHERLWTSKKILRKQ 369
+ +LQRE R++ Q R RE+ R+ ER + K L+++
Sbjct: 927 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 986
Query: 368 LEKWSWSQPEMQHK--RTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHRRQRC 195
E+ +PE + + R L Q +L ++ ++R+ Q+W + ++
Sbjct: 987 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW---ERQYRKKDEL 1043
Query: 194 GHRERCELSKKRPKTQL 144
E L ++R K +L
Sbjct: 1044 QQEEEQLLREEREKRRL 1060
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 40.3 bits (90), Expect = 0.005
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
Frame = -1
Query: 563 RQPQVQRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLE-HREQSMSRKMVIHERLWTSK 387
R+ Q++R+ Q R QQ R QLR R + +RR + REQ R HE+ +
Sbjct: 391 REQQLRREQQLRRE---QQLRREQQLR--REQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 386 KILRKQLEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHR 207
++ R+Q E+ W + E + +R + R L + ++ + +E++ R +Q R
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER---REQQER 502
Query: 206 RQRCGHRERCELSKKRPKTQ 147
R++ RE+ E ++R K Q
Sbjct: 503 REQQLRREQEERREQRLKRQ 522
Score = 33.5 bits (73), Expect = 0.58
Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
Frame = -1
Query: 563 RQPQVQRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSRKMVIHERLWTSKK 384
R+ Q +R+ Q+ R Q+ R QLR + R REQ R+ ++L ++
Sbjct: 328 REQQEERREQQLRR--EQEERREQQLRREQEEERREQQLRREQEEERR---EQQLRREQQ 382
Query: 383 ILRKQ-LEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHR 207
+ R+Q L + + E Q +R R L + QQ +R QE++ + EQ R
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 206 RQRCGHRERCE 174
R++ RE+ E
Sbjct: 443 REQRLKREQEE 453
Score = 30.7 bits (66), Expect = 4.1
Identities = 29/137 (21%), Positives = 56/137 (40%), Gaps = 2/137 (1%)
Frame = -1
Query: 548 QRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSRKMVIHERLWTSKKILRKQ 369
+ +LQRE R++ Q R RE+ R+ ER + K L+++
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969
Query: 368 LEKWSWSQPEMQHK--RTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHRRQRC 195
E+ +PE + + R L Q +L ++ ++R+ Q+W + ++
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW---ERQYRKKDEL 1026
Query: 194 GHRERCELSKKRPKTQL 144
E L ++R K +L
Sbjct: 1027 QQEEEQLLREEREKRRL 1043
Score = 30.3 bits (65), Expect = 5.4
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 1/123 (0%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRR-WLEHREQSMSRKMVIHERLWTSKKILRKQ 369
RKL+R+ +Q Q R+ R + +RR E R + + ER ++ +Q
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Query: 368 LEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHRRQRCGH 189
L + + E Q +R + R + ++ + R+EQQ R +Q RR++
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR--REQQLRREQQLR 396
Query: 188 RER 180
RE+
Sbjct: 397 REQ 399
Score = 30.3 bits (65), Expect = 5.4
Identities = 35/141 (24%), Positives = 70/141 (49%), Gaps = 3/141 (2%)
Frame = -1
Query: 560 QPQVQRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSRKMVIHERLWTSKKI 381
+P+ +R+ +RER Q R +L+ + +R E RE+ +++ ER + ++
Sbjct: 1097 EPEKRRRQERER-----QCREEEELQQEEEQLLR---EEREKRRRQEL---ERQYREEEE 1145
Query: 380 LRKQLEKWSWSQPEMQHKRTMV-QWRTNMLGQ*HMSMLV--QQHKRRQEQQWS**RLEQH 210
++++ E+ +PE + ++ + Q+R Q L+ +Q KRRQE++ E+
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 209 RRQRCGHRERCELSKKRPKTQ 147
+RQ+ R R E + K Q
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQ 1226
>BC070050-1|AAH70050.1| 1022|Homo sapiens SRRM2 protein protein.
Length = 1022
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSR 423
R+ R RSP R+ RS S+ RGRS R R +S SR
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672
>AF201422-1|AAF21439.1| 2296|Homo sapiens splicing coactivator
subunit SRm300 protein.
Length = 2296
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSR 423
R+ R RSP R+ RS S+ RGRS R R +S SR
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672
>AB016092-1|BAA83718.1| 2752|Homo sapiens RNA binding protein
protein.
Length = 2752
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSR 423
R+ R RSP R+ RS S+ RGRS R R +S SR
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672
>AB016088-1|BAA83714.1| 956|Homo sapiens RNA binding protein
protein.
Length = 956
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSR 423
R+ R RSP R+ RS S+ RGRS R R +S SR
Sbjct: 597 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 637
>AB016087-1|BAA83713.1| 1262|Homo sapiens RNA binding protein
protein.
Length = 1262
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSR 423
R+ R RSP R+ RS S+ RGRS R R +S SR
Sbjct: 422 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 462
>AB002322-1|BAA20782.3| 2800|Homo sapiens KIAA0324 protein protein.
Length = 2800
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = -1
Query: 545 RKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSR 423
R+ R RSP R+ RS S+ RGRS R R +S SR
Sbjct: 680 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 720
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens
cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 30.3 bits (65), Expect = 5.4
Identities = 29/130 (22%), Positives = 55/130 (42%)
Frame = -1
Query: 563 RQPQVQRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSRKMVIHERLWTSKK 384
RQ Q + K+ R+ R+Q + R + E + K E +W ++
Sbjct: 405 RQEQ-EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 463
Query: 383 ILRKQLEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQHKRRQEQQWS**RLEQHRR 204
+R+Q E W Q E H++ + + + + M Q+ K R++++ + E+ R
Sbjct: 464 KIREQEE--IWRQKEKMHEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 521
Query: 203 QRCGHRERCE 174
Q RE+ E
Sbjct: 522 QEEKIREQEE 531
Score = 29.5 bits (63), Expect = 9.4
Identities = 23/113 (20%), Positives = 49/113 (43%), Gaps = 1/113 (0%)
Frame = -1
Query: 572 WSWRQPQVQRKLQRERSP*RQQARSTSQLRV*RGRSMRRWLEHREQSMSRKMVIHERLWT 393
W+ Q + K+ R+ Q+ Q + + R + +E+ M R+ E +W
Sbjct: 285 WNRLNQQQEEKMWRQEEK-IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ---EEMMWE 340
Query: 392 SKKILRKQLEKWSWSQPEMQHKRTMVQW-RTNMLGQ*HMSMLVQQHKRRQEQQ 237
++ +R+Q E+ W + E + + W + + + M Q+ R QE++
Sbjct: 341 KEEKMRRQ-EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 392
>BC035621-1|AAH35621.1| 893|Homo sapiens chromosome 12 open reading
frame 25 protein.
Length = 893
Score = 29.5 bits (63), Expect = 9.4
Identities = 16/65 (24%), Positives = 31/65 (47%)
Frame = -1
Query: 440 EQSMSRKMVIHERLWTSKKILRKQLEKWSWSQPEMQHKRTMVQWRTNMLGQ*HMSMLVQQ 261
E+ R+M +LW ++ + +Q +K W+ E +H+ + QW L + VQ
Sbjct: 481 EEEFGREM--RRQLWLEEEEMWQQRQK-KWALLEQEHQEKLRQWNLEDLAREQQRRWVQL 537
Query: 260 HKRRQ 246
K ++
Sbjct: 538 EKEQE 542
>BC027450-1|AAH27450.1| 469|Homo sapiens SETD1A protein protein.
Length = 469
Score = 29.5 bits (63), Expect = 9.4
Identities = 11/32 (34%), Positives = 17/32 (53%)
Frame = +3
Query: 393 RPQPLMDHHLSRHTLLTVLQPSPHTPPTLHPQ 488
RP+PL+ H L H ++P+P P P+
Sbjct: 50 RPRPLLSHILLEHNYALAVKPTPPAPALRPPE 81
>AB002337-1|BAA20797.2| 1709|Homo sapiens KIAA0339 protein protein.
Length = 1709
Score = 29.5 bits (63), Expect = 9.4
Identities = 11/32 (34%), Positives = 17/32 (53%)
Frame = +3
Query: 393 RPQPLMDHHLSRHTLLTVLQPSPHTPPTLHPQ 488
RP+PL+ H L H ++P+P P P+
Sbjct: 1290 RPRPLLSHILLEHNYALAVKPTPPAPALRPPE 1321
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 67,589,165
Number of Sequences: 237096
Number of extensions: 1375738
Number of successful extensions: 4797
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4361
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4751
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6268037466
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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