Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-2245
(708 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC012173-1|AAH12173.1| 354|Homo sapiens KTI12 homolog, chromati... 100 6e-21
AL445685-3|CAI17029.1| 354|Homo sapiens novel protein protein. 100 6e-21
AF327348-1|AAL56009.1| 354|Homo sapiens hypothetical protein SB... 100 6e-21
AK057426-1|BAB71480.1| 723|Homo sapiens protein ( Homo sapiens ... 38 0.047
BC035344-1|AAH35344.1| 348|Homo sapiens phosphoseryl-tRNA kinas... 34 0.43
AK127173-1|BAC86867.1| 289|Homo sapiens protein ( Homo sapiens ... 34 0.43
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 31 5.3
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 31 5.3
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 31 5.3
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 31 5.3
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 31 5.3
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 30 9.3
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 30 9.3
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 30 9.3
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 30 9.3
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 30 9.3
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 30 9.3
>BC012173-1|AAH12173.1| 354|Homo sapiens KTI12 homolog, chromatin
associated (S. cerevisiae) protein.
Length = 354
Score = 100 bits (239), Expect = 6e-21
Identities = 50/113 (44%), Positives = 77/113 (68%)
Frame = +1
Query: 22 MPLIIICGTPVSGKTTRAKELKQFFEEKHGKTVEIVSEDEAIAKLGYEKNSMFLDSQKEK 201
MPL++ CG P SGK+ RA+EL+ + G+ V +V D+A A LG E +++ DS +EK
Sbjct: 1 MPLVVFCGLPYSGKSRRAEELRVALAAE-GRAVYVV--DDA-AVLGAEDPAVYGDSAREK 56
Query: 202 RVRGYLKSEAIRLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLR 360
+RG L++ R + + +VVILD NYIKG+RYELYC ++A+++ C +Y +R
Sbjct: 57 ALRGALRASVERRLSRHDVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVR 109
Score = 45.2 bits (102), Expect = 2e-04
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Frame = +1
Query: 301 ELYCA-SKASKSTQCTIYTLRNHEEAWQANQKRISTDNSDQ---------YTEEVFNALT 450
EL+ A S + S Q + EE+ A + T +S++ Y+ E+ ALT
Sbjct: 154 ELHTADSVVNGSAQADVPKELEREESGAAESPALVTPDSEKSAKHGSGAFYSPELLEALT 213
Query: 451 RLRFEEPNSNNRWDSPLFTVLPTDN-IDLENIYKVLF 558
LRFE P+S NRWD PLFT++ + + L I LF
Sbjct: 214 -LRFEAPDSRNRWDRPLFTLVGLEEPLPLAGIRSALF 249
>AL445685-3|CAI17029.1| 354|Homo sapiens novel protein protein.
Length = 354
Score = 100 bits (239), Expect = 6e-21
Identities = 50/113 (44%), Positives = 77/113 (68%)
Frame = +1
Query: 22 MPLIIICGTPVSGKTTRAKELKQFFEEKHGKTVEIVSEDEAIAKLGYEKNSMFLDSQKEK 201
MPL++ CG P SGK+ RA+EL+ + G+ V +V D+A A LG E +++ DS +EK
Sbjct: 1 MPLVVFCGLPYSGKSRRAEELRVALAAE-GRAVYVV--DDA-AVLGAEDPAVYGDSAREK 56
Query: 202 RVRGYLKSEAIRLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLR 360
+RG L++ R + + +VVILD NYIKG+RYELYC ++A+++ C +Y +R
Sbjct: 57 ALRGALRASVERRLSRHDVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVR 109
Score = 45.2 bits (102), Expect = 2e-04
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Frame = +1
Query: 301 ELYCA-SKASKSTQCTIYTLRNHEEAWQANQKRISTDNSDQ---------YTEEVFNALT 450
EL+ A S + S Q + EE+ A + T +S++ Y+ E+ ALT
Sbjct: 154 ELHTADSVVNGSAQADVPKELEREESGAAESPALVTPDSEKSAKHGSGAFYSPELLEALT 213
Query: 451 RLRFEEPNSNNRWDSPLFTVLPTDN-IDLENIYKVLF 558
LRFE P+S NRWD PLFT++ + + L I LF
Sbjct: 214 -LRFEAPDSRNRWDRPLFTLVGLEEPLPLAGIRSALF 249
>AF327348-1|AAL56009.1| 354|Homo sapiens hypothetical protein
SBBI81 protein.
Length = 354
Score = 100 bits (239), Expect = 6e-21
Identities = 50/113 (44%), Positives = 77/113 (68%)
Frame = +1
Query: 22 MPLIIICGTPVSGKTTRAKELKQFFEEKHGKTVEIVSEDEAIAKLGYEKNSMFLDSQKEK 201
MPL++ CG P SGK+ RA+EL+ + G+ V +V D+A A LG E +++ DS +EK
Sbjct: 1 MPLVVFCGLPYSGKSRRAEELRVALAAE-GRAVYVV--DDA-AVLGAEDPAVYGDSAREK 56
Query: 202 RVRGYLKSEAIRLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLR 360
+RG L++ R + + +VVILD NYIKG+RYELYC ++A+++ C +Y +R
Sbjct: 57 ALRGALRASVERRLSRHDVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVR 109
Score = 45.2 bits (102), Expect = 2e-04
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Frame = +1
Query: 301 ELYCA-SKASKSTQCTIYTLRNHEEAWQANQKRISTDNSDQ---------YTEEVFNALT 450
EL+ A S + S Q + EE+ A + T +S++ Y+ E+ ALT
Sbjct: 154 ELHTADSVVNGSAQADVPKELEREESGAAESPALVTPDSEKSAKHGSGAFYSPELLEALT 213
Query: 451 RLRFEEPNSNNRWDSPLFTVLPTDN-IDLENIYKVLF 558
LRFE P+S NRWD PLFT++ + + L I LF
Sbjct: 214 -LRFEAPDSRNRWDRPLFTLVGLEEPLPLAGIRSALF 249
>AK057426-1|BAB71480.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ32864 fis, clone TESTI2003625. ).
Length = 723
Score = 37.5 bits (83), Expect = 0.047
Identities = 21/47 (44%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Frame = +1
Query: 22 MPL-IIICGTPVSGKTTRAKELKQFFEEKHGKTVEIVSEDEAIAKLG 159
MP+ I I G P GK++ AKEL ++++ H + +++S EAIAKLG
Sbjct: 366 MPIKICILGPPAVGKSSIAKELAKYYKLHHIQLKDVIS--EAIAKLG 410
>BC035344-1|AAH35344.1| 348|Homo sapiens phosphoseryl-tRNA kinase
protein.
Length = 348
Score = 34.3 bits (75), Expect = 0.43
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +1
Query: 19 KMPLIIICGTPVSGKTTRAKELKQFFEEKHGKTVEIVSEDEAI 147
K L ++CG P +GK+T A+ L +++ G + +V+ D+ +
Sbjct: 17 KRGLCVLCGLPAAGKSTFARALAHRLQQEQGWAIGVVAYDDVM 59
>AK127173-1|BAC86867.1| 289|Homo sapiens protein ( Homo sapiens
cDNA FLJ45238 fis, clone BRCOC2001355. ).
Length = 289
Score = 34.3 bits (75), Expect = 0.43
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +1
Query: 19 KMPLIIICGTPVSGKTTRAKELKQFFEEKHGKTVEIVSEDEAI 147
K L ++CG P +GK+T A+ L +++ G + +V+ D+ +
Sbjct: 17 KRGLCVLCGLPAAGKSTFARALAHRLQQEQGWAIGVVAYDDVM 59
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 30.7 bits (66), Expect = 5.3
Identities = 19/51 (37%), Positives = 23/51 (45%)
Frame = +1
Query: 328 KSTQCTIYTLRNHEEAWQANQKRISTDNSDQYTEEVFNALTRLRFEEPNSN 480
KSTQ I+TLRN +K + D EE F L R EE + N
Sbjct: 914 KSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKN 964
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 30.7 bits (66), Expect = 5.3
Identities = 19/51 (37%), Positives = 23/51 (45%)
Frame = +1
Query: 328 KSTQCTIYTLRNHEEAWQANQKRISTDNSDQYTEEVFNALTRLRFEEPNSN 480
KSTQ I+TLRN +K + D EE F L R EE + N
Sbjct: 914 KSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKN 964
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 30.7 bits (66), Expect = 5.3
Identities = 19/51 (37%), Positives = 23/51 (45%)
Frame = +1
Query: 328 KSTQCTIYTLRNHEEAWQANQKRISTDNSDQYTEEVFNALTRLRFEEPNSN 480
KSTQ I+TLRN +K + D EE F L R EE + N
Sbjct: 914 KSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKN 964
>AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envelope
precursor protein.
Length = 1756
Score = 30.7 bits (66), Expect = 5.3
Identities = 19/51 (37%), Positives = 23/51 (45%)
Frame = +1
Query: 328 KSTQCTIYTLRNHEEAWQANQKRISTDNSDQYTEEVFNALTRLRFEEPNSN 480
KSTQ I+TLRN +K + D EE F L R EE + N
Sbjct: 914 KSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKN 964
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 30.7 bits (66), Expect = 5.3
Identities = 19/51 (37%), Positives = 23/51 (45%)
Frame = +1
Query: 328 KSTQCTIYTLRNHEEAWQANQKRISTDNSDQYTEEVFNALTRLRFEEPNSN 480
KSTQ I+TLRN +K + D EE F L R EE + N
Sbjct: 584 KSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKN 634
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 29.9 bits (64), Expect = 9.3
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 RLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLRNHEEAWQANQKRISTDNS 414
+++ K+++VI G + GYR EL ++ + +C++ + +A + D
Sbjct: 788 KVVNKESLVI-SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAK----ADDIV 842
Query: 415 DQYTEEVF-NALTRLRFEEPNSNN 483
T E+F N + L ++EP N
Sbjct: 843 GPVTHEIFENNVVHLMWQEPKEPN 866
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 29.9 bits (64), Expect = 9.3
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 RLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLRNHEEAWQANQKRISTDNS 414
+++ K+++VI G + GYR EL ++ + +C++ + +A + D
Sbjct: 800 KVVNKESLVI-SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAK----ADDIV 854
Query: 415 DQYTEEVF-NALTRLRFEEPNSNN 483
T E+F N + L ++EP N
Sbjct: 855 GPVTHEIFENNVVHLMWQEPKEPN 878
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 29.9 bits (64), Expect = 9.3
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 RLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLRNHEEAWQANQKRISTDNS 414
+++ K+++VI G + GYR EL ++ + +C++ + +A + D
Sbjct: 800 KVVNKESLVI-SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAK----ADDIV 854
Query: 415 DQYTEEVF-NALTRLRFEEPNSNN 483
T E+F N + L ++EP N
Sbjct: 855 GPVTHEIFENNVVHLMWQEPKEPN 878
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 29.9 bits (64), Expect = 9.3
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 RLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLRNHEEAWQANQKRISTDNS 414
+++ K+++VI G + GYR EL ++ + +C++ + +A + D
Sbjct: 788 KVVNKESLVI-SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAK----ADDIV 842
Query: 415 DQYTEEVF-NALTRLRFEEPNSNN 483
T E+F N + L ++EP N
Sbjct: 843 GPVTHEIFENNVVHLMWQEPKEPN 866
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 29.9 bits (64), Expect = 9.3
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Frame = +1
Query: 52 VSGKTTRAKELKQFFEEKHGKTVEIVSEDEAIAKLGY-------EKNSMFLDSQKEKRVR 210
+S + ELKQF E + K + S + + +L E M + ++ KRV+
Sbjct: 1520 ISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQ 1579
Query: 211 GYLKSEAIRLIGKDN---VVILDGSNYIKGYRYELYCASKASKSTQCTIYTLRNHEEAWQ 381
L+ E +L K+N +V + K Y++ A ++ C I L+ E +
Sbjct: 1580 EALQIERDQL--KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQK 1637
Query: 382 ANQKRISTDN 411
N + I T+N
Sbjct: 1638 LNLENIETEN 1647
>AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor variant
protein.
Length = 833
Score = 29.9 bits (64), Expect = 9.3
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 RLIGKDNVVILDGSNYIKGYRYELYCASKASKSTQCTIYTLRNHEEAWQANQKRISTDNS 414
+++ K+++VI G + GYR EL ++ + +C++ + +A + D
Sbjct: 251 KVVNKESLVI-SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAK----ADDIV 305
Query: 415 DQYTEEVF-NALTRLRFEEPNSNN 483
T E+F N + L ++EP N
Sbjct: 306 GPVTHEIFENNVVHLMWQEPKEPN 329
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,777,131
Number of Sequences: 237096
Number of extensions: 1831033
Number of successful extensions: 7986
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 7842
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7983
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8231208258
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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