Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-2176
(772 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X76228-1|CAA53814.1| 226|Homo sapiens vacuolar H+ ATPase E subu... 222 1e-57
X71491-1|CAA50592.1| 226|Homo sapiens vacuolar proton ATPase pr... 222 1e-57
CR456385-1|CAG30271.1| 226|Homo sapiens ATP6E protein. 222 1e-57
BT007128-1|AAP35792.1| 226|Homo sapiens ATPase, H+ transporting... 222 1e-57
BC004443-1|AAH04443.1| 226|Homo sapiens ATPase, H+ transporting... 222 1e-57
BC034808-1|AAH34808.1| 226|Homo sapiens ATPase, H+ transporting... 197 4e-50
BC008981-1|AAH08981.1| 226|Homo sapiens ATPase, H+ transporting... 197 4e-50
AK058055-1|BAB71643.1| 226|Homo sapiens protein ( Homo sapiens ... 197 4e-50
AC018682-1|AAY14833.1| 226|Homo sapiens unknown protein. 197 4e-50
AB074759-1|BAC00847.1| 226|Homo sapiens V-ATPase E1 subunit pro... 197 4e-50
BC112028-1|AAI12029.1| 259|Homo sapiens hypothetical protein FL... 34 0.65
BC112026-1|AAI12027.1| 259|Homo sapiens hypothetical protein LO... 34 0.65
AK097823-1|BAC05178.1| 259|Homo sapiens protein ( Homo sapiens ... 34 0.65
>X76228-1|CAA53814.1| 226|Homo sapiens vacuolar H+ ATPase E subunit
protein.
Length = 226
Score = 222 bits (542), Expect = 1e-57
Identities = 115/224 (51%), Positives = 150/224 (66%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSDADVQKQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
IQ SN++NQARLKVL+ R+D + ++L+EA++RL++V KDT Y LL L++Q
Sbjct: 63 QIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L+QL+EP + +R R+ D LV++ + KA YK K DV +++D E++L D GG+E
Sbjct: 123 GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD 762
+ +IK+SNTLESRL+LIAQQ++PE+R ALFG N NRKF D
Sbjct: 183 IYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>X71491-1|CAA50592.1| 226|Homo sapiens vacuolar proton ATPase
protein.
Length = 226
Score = 222 bits (542), Expect = 1e-57
Identities = 115/224 (51%), Positives = 150/224 (66%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSDADVQKQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDADVQKQIKHMMAFIEQEANEKAEEIDRKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
IQ SN++NQARLKVL+ R+D + ++L+EA++RL++V KDT Y LL L++Q
Sbjct: 63 QIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L+QL+EP + +R R+ D LV++ + KA YK K DV +++D E++L D GG+E
Sbjct: 123 GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD 762
+ +IK+SNTLESRL+LIAQQ++PE+R ALFG N NRKF D
Sbjct: 183 IYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>CR456385-1|CAG30271.1| 226|Homo sapiens ATP6E protein.
Length = 226
Score = 222 bits (542), Expect = 1e-57
Identities = 115/224 (51%), Positives = 150/224 (66%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSDADVQKQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
IQ SN++NQARLKVL+ R+D + ++L+EA++RL++V KDT Y LL L++Q
Sbjct: 63 QIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L+QL+EP + +R R+ D LV++ + KA YK K DV +++D E++L D GG+E
Sbjct: 123 GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD 762
+ +IK+SNTLESRL+LIAQQ++PE+R ALFG N NRKF D
Sbjct: 183 IYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>BT007128-1|AAP35792.1| 226|Homo sapiens ATPase, H+ transporting,
lysosomal 31kDa, V1 subunit E isoform 1 protein.
Length = 226
Score = 222 bits (542), Expect = 1e-57
Identities = 115/224 (51%), Positives = 150/224 (66%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSDADVQKQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
IQ SN++NQARLKVL+ R+D + ++L+EA++RL++V KDT Y LL L++Q
Sbjct: 63 QIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L+QL+EP + +R R+ D LV++ + KA YK K DV +++D E++L D GG+E
Sbjct: 123 GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD 762
+ +IK+SNTLESRL+LIAQQ++PE+R ALFG N NRKF D
Sbjct: 183 IYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>BC004443-1|AAH04443.1| 226|Homo sapiens ATPase, H+ transporting,
lysosomal 31kDa, V1 subunit E1 protein.
Length = 226
Score = 222 bits (542), Expect = 1e-57
Identities = 115/224 (51%), Positives = 150/224 (66%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSDADVQKQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
IQ SN++NQARLKVL+ R+D + ++L+EA++RL++V KDT Y LL L++Q
Sbjct: 63 QIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L+QL+EP + +R R+ D LV++ + KA YK K DV +++D E++L D GG+E
Sbjct: 123 GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD 762
+ +IK+SNTLESRL+LIAQQ++PE+R ALFG N NRKF D
Sbjct: 183 IYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
>BC034808-1|AAH34808.1| 226|Homo sapiens ATPase, H+ transporting,
lysosomal 31kDa, V1 subunit E2 protein.
Length = 226
Score = 197 bits (480), Expect = 4e-50
Identities = 105/222 (47%), Positives = 139/222 (62%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSD DV+KQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
I S M NQARLKVL+ R D + ++L EA+ RL+ + +D ++Y LL L++Q
Sbjct: 63 QIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L +L+EP + +R R D LVE+ + KA +Y +K V +++D E +L+ + GG+E
Sbjct: 123 GLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKF 756
+ + RIK+SNTLESRL+L A+Q +PEIR ALFG N NRKF
Sbjct: 183 VYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKF 224
>BC008981-1|AAH08981.1| 226|Homo sapiens ATPase, H+ transporting,
lysosomal 31kDa, V1 subunit E2 protein.
Length = 226
Score = 197 bits (480), Expect = 4e-50
Identities = 105/222 (47%), Positives = 139/222 (62%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSD DV+KQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
I S M NQARLKVL+ R D + ++L EA+ RL+ + +D ++Y LL L++Q
Sbjct: 63 QIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L +L+EP + +R R D LVE+ + KA +Y +K V +++D E +L+ + GG+E
Sbjct: 123 GLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKF 756
+ + RIK+SNTLESRL+L A+Q +PEIR ALFG N NRKF
Sbjct: 183 VYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKF 224
>AK058055-1|BAB71643.1| 226|Homo sapiens protein ( Homo sapiens
cDNA FLJ25326 fis, clone TST00424. ).
Length = 226
Score = 197 bits (480), Expect = 4e-50
Identities = 105/222 (47%), Positives = 139/222 (62%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSD DV+KQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
I S M NQARLKVL+ R D + ++L EA+ RL+ + +D ++Y LL L++Q
Sbjct: 63 QIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L +L+EP + +R R D LVE+ + KA +Y +K V +++D E +L+ + GG+E
Sbjct: 123 GLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKF 756
+ + RIK+SNTLESRL+L A+Q +PEIR ALFG N NRKF
Sbjct: 183 VYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKF 224
>AC018682-1|AAY14833.1| 226|Homo sapiens unknown protein.
Length = 226
Score = 197 bits (480), Expect = 4e-50
Identities = 105/222 (47%), Positives = 139/222 (62%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSD DV+KQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
I S M NQARLKVL+ R D + ++L EA+ RL+ + +D ++Y LL L++Q
Sbjct: 63 QIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L +L+EP + +R R D LVE+ + KA +Y +K V +++D E +L+ + GG+E
Sbjct: 123 GLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKF 756
+ + RIK+SNTLESRL+L A+Q +PEIR ALFG N NRKF
Sbjct: 183 VYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKF 224
>AB074759-1|BAC00847.1| 226|Homo sapiens V-ATPase E1 subunit
protein.
Length = 226
Score = 197 bits (480), Expect = 4e-50
Identities = 105/222 (47%), Positives = 139/222 (62%)
Frame = +1
Query: 91 LSDADVQKQIKHMMAFIEQXXXXXXXXXXXXXXXXFNIEKGRLVQQQRLKIMXXXXXXXX 270
LSD DV+KQIKHMMAFIEQ FNIEKGRLVQ QRLKIM
Sbjct: 3 LSDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEK 62
Query: 271 XXXXXXXIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDTKLYSELLVTLIVQ 450
I S M NQARLKVL+ R D + ++L EA+ RL+ + +D ++Y LL L++Q
Sbjct: 63 QIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLVLQ 122
Query: 451 ALFQLMEPTVTIRVRQTDKALVESLLGKAQTDYKNKIKKDVVLKVDTENFLSPDTCGGIE 630
L +L+EP + +R R D LVE+ + KA +Y +K V +++D E +L+ + GG+E
Sbjct: 123 GLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGGVE 182
Query: 631 LVAARGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKF 756
+ + RIK+SNTLESRL+L A+Q +PEIR ALFG N NRKF
Sbjct: 183 VYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKF 224
>BC112028-1|AAI12029.1| 259|Homo sapiens hypothetical protein
FLJ40504 protein.
Length = 259
Score = 33.9 bits (74), Expect = 0.65
Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Frame = -1
Query: 433 PAALSTVW------CPLALQPGACELRQVHYVRDLHELSVPSDELGS-ACSKIGSS 287
P+AL+ W CPLAL PG EL H + LH+L VP G+ C+++ SS
Sbjct: 15 PSALTKNWPSKPESCPLALLPGQHELH--HLLHPLHQLPVPGHCPGTQLCAQLVSS 68
>BC112026-1|AAI12027.1| 259|Homo sapiens hypothetical protein
LOC284085 protein.
Length = 259
Score = 33.9 bits (74), Expect = 0.65
Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Frame = -1
Query: 433 PAALSTVW------CPLALQPGACELRQVHYVRDLHELSVPSDELGS-ACSKIGSS 287
P+AL+ W CPLAL PG EL H + LH+L VP G+ C+++ SS
Sbjct: 15 PSALTKNWPSKPESCPLALLPGQHELH--HLLHPLHQLPVPGHCPGTQLCAQLVSS 68
>AK097823-1|BAC05178.1| 259|Homo sapiens protein ( Homo sapiens
cDNA FLJ40504 fis, clone TESTI2045509, highly similar to
KERATIN, TYPE I CYTOSKELETAL 18. ).
Length = 259
Score = 33.9 bits (74), Expect = 0.65
Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Frame = -1
Query: 433 PAALSTVW------CPLALQPGACELRQVHYVRDLHELSVPSDELGS-ACSKIGSS 287
P+AL+ W CPLAL PG EL H + LH+L VP G+ C+++ SS
Sbjct: 15 PSALTKNWPSKPESCPLALLPGQHELH--HLLHPLHQLPVPGHCPGTQLCAQLVSS 68
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,360,809
Number of Sequences: 237096
Number of extensions: 2247946
Number of successful extensions: 6209
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5951
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6197
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9311505506
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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