Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-1548
(708 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L38951-1|AAC41763.1| 876|Homo sapiens importin beta subunit pro... 220 3e-57
BT009797-1|AAP88799.1| 876|Homo sapiens karyopherin (importin) ... 220 3e-57
BC036703-1|AAH36703.1| 876|Homo sapiens karyopherin (importin) ... 220 3e-57
BC024045-1|AAH24045.1| 876|Homo sapiens karyopherin (importin) ... 220 3e-57
BC003572-1|AAH03572.1| 876|Homo sapiens karyopherin (importin) ... 220 3e-57
L39793-1|AAA82869.1| 876|Homo sapiens nuclear factor p97 protein. 220 5e-57
AB040942-1|BAA96033.1| 1326|Homo sapiens KIAA1509 protein protein. 32 1.7
BC131711-1|AAI31712.1| 676|Homo sapiens GRB2-associated binding... 30 7.1
AB018413-1|BAA76737.1| 676|Homo sapiens Gab2 protein. 30 7.1
AB011143-1|BAA25497.2| 683|Homo sapiens KIAA0571 protein protein. 30 7.1
Z69028-1|CAA93152.1| 494|Homo sapiens beta 2 isoform of 61kDa r... 30 9.3
L42374-1|AAC37602.1| 497|Homo sapiens protein phosphatase 2A B5... 30 9.3
BC045619-1|AAH45619.1| 497|Homo sapiens PPP2R5B protein protein. 30 9.3
>L38951-1|AAC41763.1| 876|Homo sapiens importin beta subunit
protein.
Length = 876
Score = 220 bits (538), Expect = 3e-57
Identities = 110/175 (62%), Positives = 132/175 (75%)
Frame = +3
Query: 105 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 284
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 285 LKNHLTSKDPTLKQQYQQRWLALAEDVRLYIKENILAAIGTENSRPSSAAQCVAYVAVAE 464
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GTE RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 465 LPVGQWNDLIPILVENVVHVQSTELKKEATLEAIGYICQDIDAEVLTERSNQILT 629
+PV QW +LIP LV NV + STE KE+TLEAIGYICQDID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/30 (70%), Positives = 24/30 (80%)
Frame = +1
Query: 619 KFLPAIIHGMRSTEPSNHVRLAATQALLNS 708
+ L AII GMR EPSN+V+LAAT ALLNS
Sbjct: 172 EILTAIIQGMRKEEPSNNVKLAATNALLNS 201
>BT009797-1|AAP88799.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 220 bits (538), Expect = 3e-57
Identities = 110/175 (62%), Positives = 132/175 (75%)
Frame = +3
Query: 105 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 284
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 285 LKNHLTSKDPTLKQQYQQRWLALAEDVRLYIKENILAAIGTENSRPSSAAQCVAYVAVAE 464
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GTE RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 465 LPVGQWNDLIPILVENVVHVQSTELKKEATLEAIGYICQDIDAEVLTERSNQILT 629
+PV QW +LIP LV NV + STE KE+TLEAIGYICQDID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/30 (70%), Positives = 24/30 (80%)
Frame = +1
Query: 619 KFLPAIIHGMRSTEPSNHVRLAATQALLNS 708
+ L AII GMR EPSN+V+LAAT ALLNS
Sbjct: 172 EILTAIIQGMRKEEPSNNVKLAATNALLNS 201
>BC036703-1|AAH36703.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 220 bits (538), Expect = 3e-57
Identities = 110/175 (62%), Positives = 132/175 (75%)
Frame = +3
Query: 105 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 284
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 285 LKNHLTSKDPTLKQQYQQRWLALAEDVRLYIKENILAAIGTENSRPSSAAQCVAYVAVAE 464
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GTE RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 465 LPVGQWNDLIPILVENVVHVQSTELKKEATLEAIGYICQDIDAEVLTERSNQILT 629
+PV QW +LIP LV NV + STE KE+TLEAIGYICQDID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/30 (70%), Positives = 24/30 (80%)
Frame = +1
Query: 619 KFLPAIIHGMRSTEPSNHVRLAATQALLNS 708
+ L AII GMR EPSN+V+LAAT ALLNS
Sbjct: 172 EILTAIIQGMRKEEPSNNVKLAATNALLNS 201
>BC024045-1|AAH24045.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 220 bits (538), Expect = 3e-57
Identities = 110/175 (62%), Positives = 132/175 (75%)
Frame = +3
Query: 105 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 284
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 285 LKNHLTSKDPTLKQQYQQRWLALAEDVRLYIKENILAAIGTENSRPSSAAQCVAYVAVAE 464
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GTE RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 465 LPVGQWNDLIPILVENVVHVQSTELKKEATLEAIGYICQDIDAEVLTERSNQILT 629
+PV QW +LIP LV NV + STE KE+TLEAIGYICQDID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/30 (70%), Positives = 24/30 (80%)
Frame = +1
Query: 619 KFLPAIIHGMRSTEPSNHVRLAATQALLNS 708
+ L AII GMR EPSN+V+LAAT ALLNS
Sbjct: 172 EILTAIIQGMRKEEPSNNVKLAATNALLNS 201
>BC003572-1|AAH03572.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 220 bits (538), Expect = 3e-57
Identities = 110/175 (62%), Positives = 132/175 (75%)
Frame = +3
Query: 105 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 284
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 285 LKNHLTSKDPTLKQQYQQRWLALAEDVRLYIKENILAAIGTENSRPSSAAQCVAYVAVAE 464
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GTE RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 465 LPVGQWNDLIPILVENVVHVQSTELKKEATLEAIGYICQDIDAEVLTERSNQILT 629
+PV QW +LIP LV NV + STE KE+TLEAIGYICQDID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/30 (70%), Positives = 24/30 (80%)
Frame = +1
Query: 619 KFLPAIIHGMRSTEPSNHVRLAATQALLNS 708
+ L AII GMR EPSN+V+LAAT ALLNS
Sbjct: 172 EILTAIIQGMRKEEPSNNVKLAATNALLNS 201
>L39793-1|AAA82869.1| 876|Homo sapiens nuclear factor p97 protein.
Length = 876
Score = 220 bits (537), Expect = 5e-57
Identities = 110/175 (62%), Positives = 132/175 (75%)
Frame = +3
Query: 105 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 284
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 285 LKNHLTSKDPTLKQQYQQRWLALAEDVRLYIKENILAAIGTENSRPSSAAQCVAYVAVAE 464
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GTE RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLHTLGTETYRPSSASQCVAGIACAE 120
Query: 465 LPVGQWNDLIPILVENVVHVQSTELKKEATLEAIGYICQDIDAEVLTERSNQILT 629
+PV QW +LIP LV NV + STE KE+TLEAIGYICQDID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/30 (70%), Positives = 24/30 (80%)
Frame = +1
Query: 619 KFLPAIIHGMRSTEPSNHVRLAATQALLNS 708
+ L AII GMR EPSN+V+LAAT ALLNS
Sbjct: 172 EILTAIIQGMRKEEPSNNVKLAATNALLNS 201
>AB040942-1|BAA96033.1| 1326|Homo sapiens KIAA1509 protein protein.
Length = 1326
Score = 32.3 bits (70), Expect = 1.7
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Frame = +3
Query: 90 HAETTLTLIQILEKTVSPDRN------ELEAAVRYLDHAATTNFTTFIKMLS----DVLL 239
H E T+ L+++ ++ + +RN E + L H T N T ++L+ L
Sbjct: 343 HKEATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFL 402
Query: 240 QGGNSQVARMAAGLQLKNH-LTSKDPTLKQQY 332
Q N+ + A LQ++N L+S+ L QY
Sbjct: 403 QEHNTTLQTQTAKLQVENSTLSSQSAALTAQY 434
>BC131711-1|AAI31712.1| 676|Homo sapiens GRB2-associated binding
protein 2 protein.
Length = 676
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = -2
Query: 329 LLFKCRIFRSEMIFQLQTSCHPSHLTVTTLEKDIGQHFDECCEICGGSMVEVSNCCFQFI 150
L F + + +F ++TS +L T E+D+ + C+ICG + E S + +
Sbjct: 73 LTFNKKELQDSFVFDIKTSERTFYLVAET-EEDMNKWVQSICQICGFNQAEESTDSLRNV 131
Query: 149 S 147
S
Sbjct: 132 S 132
>AB018413-1|BAA76737.1| 676|Homo sapiens Gab2 protein.
Length = 676
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = -2
Query: 329 LLFKCRIFRSEMIFQLQTSCHPSHLTVTTLEKDIGQHFDECCEICGGSMVEVSNCCFQFI 150
L F + + +F ++TS +L T E+D+ + C+ICG + E S + +
Sbjct: 73 LTFNKKELQDSFVFDIKTSERTFYLVAET-EEDMNKWVQSICQICGFNQAEESTDSLRNV 131
Query: 149 S 147
S
Sbjct: 132 S 132
>AB011143-1|BAA25497.2| 683|Homo sapiens KIAA0571 protein protein.
Length = 683
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = -2
Query: 329 LLFKCRIFRSEMIFQLQTSCHPSHLTVTTLEKDIGQHFDECCEICGGSMVEVSNCCFQFI 150
L F + + +F ++TS +L T E+D+ + C+ICG + E S + +
Sbjct: 80 LTFNKKELQDSFVFDIKTSERTFYLVAET-EEDMNKWVQSICQICGFNQAEESTDSLRNV 138
Query: 149 S 147
S
Sbjct: 139 S 139
>Z69028-1|CAA93152.1| 494|Homo sapiens beta 2 isoform of 61kDa
regulatory subunit of PP2A protein.
Length = 494
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/58 (20%), Positives = 26/58 (44%)
Frame = +3
Query: 63 HKLKNSETMHAETTLTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVL 236
H +K+ HA+ ++Q LEK + + + ++Y T F+ + ++L
Sbjct: 283 HSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEIL 340
>L42374-1|AAC37602.1| 497|Homo sapiens protein phosphatase 2A
B56-beta protein.
Length = 497
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/58 (20%), Positives = 26/58 (44%)
Frame = +3
Query: 63 HKLKNSETMHAETTLTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVL 236
H +K+ HA+ ++Q LEK + + + ++Y T F+ + ++L
Sbjct: 286 HSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEIL 343
>BC045619-1|AAH45619.1| 497|Homo sapiens PPP2R5B protein protein.
Length = 497
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/58 (20%), Positives = 26/58 (44%)
Frame = +3
Query: 63 HKLKNSETMHAETTLTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVL 236
H +K+ HA+ ++Q LEK + + + ++Y T F+ + ++L
Sbjct: 286 HSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEIL 343
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,012,772
Number of Sequences: 237096
Number of extensions: 1979173
Number of successful extensions: 8089
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7917
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8089
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8231208258
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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