Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-1306
(796 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VW35 Cluster: CG8743-PA; n=6; Endopterygota|Rep: CG87... 217 3e-55
UniRef50_Q8T666 Cluster: CUP-5L; n=5; Caenorhabditis|Rep: CUP-5L... 109 8e-23
UniRef50_UPI0000E4616D Cluster: PREDICTED: similar to mucolipin-... 94 4e-18
UniRef50_Q4RU61 Cluster: Chromosome 1 SCAF14995, whole genome sh... 86 8e-16
UniRef50_Q9GZU1 Cluster: Mucolipin-1; n=83; Coelomata|Rep: Mucol... 86 1e-15
UniRef50_Q99J21 Cluster: Mucolipin-1; n=11; Euteleostomi|Rep: Mu... 85 1e-15
UniRef50_A7S163 Cluster: Predicted protein; n=2; Nematostella ve... 83 6e-15
UniRef50_Q4RZS0 Cluster: Chromosome 18 SCAF14786, whole genome s... 82 2e-14
UniRef50_Q52KN5 Cluster: MGC115291 protein; n=2; Xenopus|Rep: MG... 79 1e-13
UniRef50_UPI00004D7419 Cluster: Mucolipin-2.; n=1; Xenopus tropi... 79 1e-13
UniRef50_A7S161 Cluster: Predicted protein; n=1; Nematostella ve... 73 8e-12
UniRef50_A0DNM4 Cluster: Chromosome undetermined scaffold_58, wh... 37 0.51
UniRef50_A6LRY0 Cluster: Putative uncharacterized protein; n=2; ... 35 2.7
UniRef50_Q8S479 Cluster: Putative pol protein; n=1; Zea mays|Rep... 35 2.7
UniRef50_Q23DW9 Cluster: Putative uncharacterized protein; n=1; ... 34 3.6
UniRef50_UPI00006CD094 Cluster: hypothetical protein TTHERM_0019... 33 6.2
UniRef50_Q7XBD2 Cluster: Retrotransposon Opie-2; n=1; Zea mays|R... 33 6.2
UniRef50_Q8RE47 Cluster: Serine protease, V8 family; n=1; Fusoba... 33 8.3
>UniRef50_Q9VW35 Cluster: CG8743-PA; n=6; Endopterygota|Rep:
CG8743-PA - Drosophila melanogaster (Fruit fly)
Length = 652
Score = 217 bits (530), Expect = 3e-55
Identities = 96/149 (64%), Positives = 115/149 (77%)
Frame = +2
Query: 239 PNANNEQDFPHQSTSFSPPTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVL 418
P+ + ++ P S S + EE+MRRKLQFFFMNPIEKW+AKRKFPYKFVVQ++KI L
Sbjct: 71 PSVDGREEQPEFPGS-SAASYQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFL 129
Query: 419 VTFQLCLFAHNRYNHVNYTWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYN 598
VT QLCLFAH+RYNH+NYT DNR AFSHLFL GWDS+RE+ +YPP GP ALY EF++
Sbjct: 130 VTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFD 189
Query: 599 TLDYAVAGYTNLSNAIGPYSYNDENNFMP 685
T+ YAV GY N+S +IGPY Y NN MP
Sbjct: 190 TVQYAVNGYANVSRSIGPYDYPTPNNTMP 218
Score = 36.3 bits (80), Expect = 0.89
Identities = 13/24 (54%), Positives = 18/24 (75%)
Frame = +3
Query: 708 NYKQGIIYGFNESYQFNSEVFETC 779
NY++G I+GFNESY F+ + E C
Sbjct: 226 NYREGTIFGFNESYIFDPHIDEVC 249
>UniRef50_Q8T666 Cluster: CUP-5L; n=5; Caenorhabditis|Rep: CUP-5L -
Caenorhabditis elegans
Length = 668
Score = 109 bits (262), Expect = 8e-23
Identities = 56/147 (38%), Positives = 80/147 (54%), Gaps = 4/147 (2%)
Frame = +2
Query: 236 RPNANNEQ---DFPHQSTSFSPPTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVI 406
RP N ++ D PH + E++RR LQFFFMNP+EKWK + + PYK V+QV+
Sbjct: 26 RPTINFQEIMEDLPHHER------ETGERLRRHLQFFFMNPMEKWKVRHQLPYKLVLQVL 79
Query: 407 KIVLVTFQLCLFAHNRYNHVNYTWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKID 586
KIV VT QL LFA R +HV++ D H FL W+ R+ YPP G ++Y
Sbjct: 80 KIVFVTMQLILFAEMRMSHVDFLEDTTTVMRHRFLKEWNDDRDALQYPPAEGRYSVYDDQ 139
Query: 587 EFYNTLDYAVAGYTNLSN-AIGPYSYN 664
L + + Y ++ N + +SY+
Sbjct: 140 GLSEHLSFLINSYYSIRNDSFASFSYD 166
>UniRef50_UPI0000E4616D Cluster: PREDICTED: similar to mucolipin-3;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to mucolipin-3 - Strongylocentrotus purpuratus
Length = 696
Score = 93.9 bits (223), Expect = 4e-18
Identities = 50/144 (34%), Positives = 84/144 (58%), Gaps = 1/144 (0%)
Frame = +2
Query: 236 RPNANNEQDFPHQSTSFSPPTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIV 415
+P ++ E+D TS +E MR +L++FFMNP K+K + + P+K +Q++KI+
Sbjct: 136 KPTSSMEEDDVF-GTSIGTLRSRQE-MRWELRYFFMNPYLKYKKRGRKPWKLGIQLLKII 193
Query: 416 LVTFQLCLFAHNRYNHVNYTWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFY 595
VT QL LF ++++ + N+ +F HLFL W++ + AYP A+Y+ + +
Sbjct: 194 FVTIQLVLFGTSQFSLNKFYEGNQESFEHLFLKDWNTGYDSTAYPKSDELYAIYEKEVLF 253
Query: 596 NTLDYAVAGYTNL-SNAIGPYSYN 664
LDY ++NL +NAIG Y Y+
Sbjct: 254 RHLDYVAYQFSNLETNAIGTYGYD 277
>UniRef50_Q4RU61 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF14995, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 546
Score = 86.2 bits (204), Expect = 8e-16
Identities = 46/135 (34%), Positives = 79/135 (58%), Gaps = 1/135 (0%)
Frame = +2
Query: 275 STSFSPPTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNR 454
S+S S T ++ +R L+F+FMNP EK++A++ P+K VQV+KI++VT QL LF +
Sbjct: 15 SSSVSQDTVKDDSLRDDLRFYFMNPCEKYQARKHIPWKLGVQVLKIIMVTTQLVLFGLSN 74
Query: 455 YNHVNYTWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNL 634
V+Y ++ +AF LF+ R+ A++ +FY+++ YA Y+ L
Sbjct: 75 QLVVSYKEESTMAFKQLFV------RDYGGEDQDGYCTAVFTQQDFYHSVFYATEQYSQL 128
Query: 635 SN-AIGPYSYNDENN 676
++GP SY+++ N
Sbjct: 129 GQLSVGPLSYSEDEN 143
>UniRef50_Q9GZU1 Cluster: Mucolipin-1; n=83; Coelomata|Rep:
Mucolipin-1 - Homo sapiens (Human)
Length = 580
Score = 85.8 bits (203), Expect = 1e-15
Identities = 51/128 (39%), Positives = 78/128 (60%), Gaps = 3/128 (2%)
Frame = +2
Query: 287 SPPTQMEEK-MRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNH 463
+PPT EE+ +RR+L++FFM+P +K++AK + P K ++QV+KI++VT QL LF +
Sbjct: 31 APPTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLA 90
Query: 464 VNYTWDNRIAFSHLFLLGWDSTREINAYPPGA-GPLALYKIDEFYNTLDYAVAGYTNLSN 640
V + +N IAF HLFLLG Y GA A Y ++ Y + +AV Y L +
Sbjct: 91 VTFREENTIAFRHLFLLG---------YSDGADDTFAAYTREQLYQAIFHAVDQYLALPD 141
Query: 641 -AIGPYSY 661
++G Y+Y
Sbjct: 142 VSLGRYAY 149
>UniRef50_Q99J21 Cluster: Mucolipin-1; n=11; Euteleostomi|Rep:
Mucolipin-1 - Mus musculus (Mouse)
Length = 580
Score = 85.4 bits (202), Expect = 1e-15
Identities = 50/130 (38%), Positives = 77/130 (59%), Gaps = 2/130 (1%)
Frame = +2
Query: 278 TSFSPPTQMEEK-MRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNR 454
TS +P T EE+ +RR+L++FFM+P +K++AK + P K ++QV+KI++VT QL LF +
Sbjct: 28 TSPAPTTPTEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSN 87
Query: 455 YNHVNYTWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNL 634
V + +N IAF HLFLLG+ + A Y ++ Y + YAV Y L
Sbjct: 88 QLVVTFREENTIAFRHLFLLGYSDGSD--------DTFAAYTQEQLYQAIFYAVDQYLIL 139
Query: 635 SN-AIGPYSY 661
++G Y+Y
Sbjct: 140 PEISLGRYAY 149
>UniRef50_A7S163 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 475
Score = 83.4 bits (197), Expect = 6e-15
Identities = 45/127 (35%), Positives = 75/127 (59%)
Frame = +2
Query: 311 KMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNHVNYTWDNRI 490
++R ++++ FMNP EK+KA+ + P+K ++Q+ KI++VT Q+ LF +R++ VN+ DN+
Sbjct: 1 RLRAQIEYHFMNPWEKYKARNRKPWKLLIQIFKIIIVTVQVYLFGADRFSVVNFMDDNQE 60
Query: 491 AFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNLSNAIGPYSYNDE 670
A +LFL D + NA +Y ++ Y L YA Y N++ A G Y+Y D
Sbjct: 61 ALRYLFLK--DYGGDANAV------RTVYTKNQVYMYLKYAHEQYYNIAEAAGSYAYTDL 112
Query: 671 NNFMPDP 691
+ F P
Sbjct: 113 DIFGDPP 119
>UniRef50_Q4RZS0 Cluster: Chromosome 18 SCAF14786, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF14786, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 554
Score = 81.8 bits (193), Expect = 2e-14
Identities = 44/120 (36%), Positives = 70/120 (58%), Gaps = 1/120 (0%)
Frame = +2
Query: 305 EEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNHVNYTWDN 484
EE +RRKL++FFM+P +K+ AK + PYK V+Q++KI++VT QL +F + V + +N
Sbjct: 2 EECLRRKLKYFFMSPCDKYHAKGRKPYKLVLQLLKIIIVTAQLVMFGLSNQVVVTFKEEN 61
Query: 485 RIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNL-SNAIGPYSY 661
+ F HLFL +D + + + A+Y + Y + YAV Y L +G Y+Y
Sbjct: 62 TMTFKHLFLKDYDESSDAS--------FAVYTQKDVYEHIFYAVDQYLALPETTVGRYAY 113
>UniRef50_Q52KN5 Cluster: MGC115291 protein; n=2; Xenopus|Rep:
MGC115291 protein - Xenopus laevis (African clawed frog)
Length = 497
Score = 79.4 bits (187), Expect = 1e-13
Identities = 47/129 (36%), Positives = 72/129 (55%), Gaps = 1/129 (0%)
Frame = +2
Query: 293 PTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNHVNY 472
P+ E ++RR+L++FFM+P +K++AK + PYK +Q++KI+ VT QL LF + V +
Sbjct: 38 PSPEEIQLRRRLKYFFMSPCDKFRAKGRKPYKLGLQLLKIMFVTVQLILFGLSNQMVVQF 97
Query: 473 TWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNLSN-AIG 649
+N AF HLFL + + Y A+Y ++ Y L YAV Y +LSN
Sbjct: 98 KEENTEAFKHLFLKDYTDDAD-KTY-------AIYTQEDVYEHLYYAVEQYFSLSNQTTA 149
Query: 650 PYSYNDENN 676
Y+Y N
Sbjct: 150 RYAYTQHFN 158
>UniRef50_UPI00004D7419 Cluster: Mucolipin-2.; n=1; Xenopus
tropicalis|Rep: Mucolipin-2. - Xenopus tropicalis
Length = 533
Score = 79.0 bits (186), Expect = 1e-13
Identities = 44/137 (32%), Positives = 79/137 (57%), Gaps = 2/137 (1%)
Frame = +2
Query: 257 QDFPH-QSTSFSPPTQMEEKMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQL 433
+DFP + TS + + E ++ L+F+FMNP +K++A+ + P+K ++QV+KIV+VT QL
Sbjct: 12 RDFPWARRTSMAQLDREENILKEDLKFYFMNPCDKYRARHQIPWKLLLQVLKIVMVTTQL 71
Query: 434 CLFAHNRYNHVNYTWDNRIAFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYA 613
LF + V+Y ++ +AF HLFL G+ E + +Y + Y+++ +A
Sbjct: 72 VLFGLSNQLVVSYKEESTMAFKHLFLKGYTGRDEDDC------SRTVYTQKDVYDSIFFA 125
Query: 614 VAGYTNLSN-AIGPYSY 661
+ Y L ++G +Y
Sbjct: 126 IEQYRRLKEISLGTVAY 142
>UniRef50_A7S161 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 463
Score = 72.9 bits (171), Expect = 8e-12
Identities = 41/117 (35%), Positives = 73/117 (62%), Gaps = 1/117 (0%)
Frame = +2
Query: 311 KMRRKLQFFFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNHVNYTWDNRI 490
++R++L+ FM P +K+K + + P+K ++Q+IKI++VT Q+CLF + ++ V+Y +N
Sbjct: 1 QIRKRLKSHFMTPYQKFKHRGRKPWKLLIQLIKIIIVTAQVCLFGNELFSIVDYLENNLD 60
Query: 491 AFSHLFLLGWDSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNLS-NAIGPYS 658
F+HLF+L +STR A A+Y +FY + + + Y +S +A+G YS
Sbjct: 61 TFNHLFIL--NSTR--------ANGGAIYTRTQFYTQVRHTLNQYYAISQDAVGVYS 107
>UniRef50_A0DNM4 Cluster: Chromosome undetermined scaffold_58, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_58,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 654
Score = 37.1 bits (82), Expect = 0.51
Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Frame = +2
Query: 335 FFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFA-HNRYN 460
F ++P EK+ +FP+KF++ + + TFQ+ L + H YN
Sbjct: 14 FTLSPFEKYSKYGRFPFKFLISCALVFMTTFQVILISEHYTYN 56
>UniRef50_A6LRY0 Cluster: Putative uncharacterized protein; n=2;
Clostridium beijerinckii NCIMB 8052|Rep: Putative
uncharacterized protein - Clostridium beijerinckii NCIMB
8052
Length = 492
Score = 34.7 bits (76), Expect = 2.7
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +2
Query: 602 LDYAVAGYTNLSNAIGPYSYNDENNFMPDPVFW 700
LDY + Y+ S+ YSYN NF+PD + W
Sbjct: 407 LDYTIPRYSGTSSNHTSYSYNISLNFVPDLILW 439
>UniRef50_Q8S479 Cluster: Putative pol protein; n=1; Zea mays|Rep:
Putative pol protein - Zea mays (Maize)
Length = 1553
Score = 34.7 bits (76), Expect = 2.7
Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Frame = +2
Query: 41 YYSNLKFYVAF-QTLVIVKKTSSNVRDKLTLSF*KIILEVIPMDEIMHAPDDTTCSEGED 217
Y SN K Y F ++ +V+ +S V D+ S + ++++ +DE +D +
Sbjct: 926 YDSNTKAYRVFNKSSGLVEVSSDVVFDETNGSPREQVVDLDDVDE-----EDVPTAAIRT 980
Query: 218 DHKKEIRPNANNEQDFPHQSTSFSPPTQMEEKMRRK 325
++RP EQD P ST PPTQ +E++ ++
Sbjct: 981 MAIGDVRPQEQKEQDQPSSSTMVHPPTQDDEQVHQE 1016
>UniRef50_Q23DW9 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 837
Score = 34.3 bits (75), Expect = 3.6
Identities = 15/39 (38%), Positives = 27/39 (69%)
Frame = +2
Query: 335 FFMNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHN 451
F ++PIEK++ K+P K +V V+ ++L T Q+ L++ N
Sbjct: 76 FLLSPIEKYQKYGKWPIKLIVHVMLVLLTTSQI-LYSSN 113
>UniRef50_UPI00006CD094 Cluster: hypothetical protein
TTHERM_00191760; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00191760 - Tetrahymena
thermophila SB210
Length = 592
Score = 33.5 bits (73), Expect = 6.2
Identities = 23/106 (21%), Positives = 50/106 (47%)
Frame = +2
Query: 341 MNPIEKWKAKRKFPYKFVVQVIKIVLVTFQLCLFAHNRYNHVNYTWDNRIAFSHLFLLGW 520
++P +K+ +FP+KF++ ++ ++ T+Q R +H + F ++ L G
Sbjct: 9 LSPFQKYYKFNRFPWKFLIHILLVIFTTYQALSMVSLRTSH---SRAQHQVFKYI-LFGS 64
Query: 521 DSTREINAYPPGAGPLALYKIDEFYNTLDYAVAGYTNLSNAIGPYS 658
D E N+ P YK+++F + +NL++ + Y+
Sbjct: 65 DD--ESNSVP-------FYKLEQFTENVRNVCTTLSNLNDKLLQYA 101
>UniRef50_Q7XBD2 Cluster: Retrotransposon Opie-2; n=1; Zea mays|Rep:
Retrotransposon Opie-2 - Zea mays (Maize)
Length = 1512
Score = 33.5 bits (73), Expect = 6.2
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 41 YYSNLKFYVAF-QTLVIVKKTSSNVRDKLTLSF*KIILEVIPMDEIMHAPDDTTCSEGED 217
Y SN K Y F ++ +V+ +S V D+ S + +++ +DE +D +
Sbjct: 936 YDSNTKAYRVFNKSSGLVEVSSDVVFDETNGSPREQVVDCDDVDE-----EDVPTAAIRT 990
Query: 218 DHKKEIRPNANNEQDFPHQSTSFSPPTQMEEK 313
E+RP +E+D P ST+ PPTQ +E+
Sbjct: 991 MAIGEVRPQEQDERDQPSSSTTVHPPTQDDEQ 1022
>UniRef50_Q8RE47 Cluster: Serine protease, V8 family; n=1;
Fusobacterium nucleatum subsp. nucleatum|Rep: Serine
protease, V8 family - Fusobacterium nucleatum subsp.
nucleatum
Length = 579
Score = 33.1 bits (72), Expect = 8.3
Identities = 12/33 (36%), Positives = 20/33 (60%)
Frame = +2
Query: 599 TLDYAVAGYTNLSNAIGPYSYNDENNFMPDPVF 697
T ++ + Y SN+I ++Y D+ NFMP P +
Sbjct: 110 TNNHVINSYEVASNSIAEFNYQDDENFMPCPTY 142
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 728,105,820
Number of Sequences: 1657284
Number of extensions: 14972165
Number of successful extensions: 37931
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 36234
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37908
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67908372675
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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