Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-0644
(571 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 220 2e-56
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 186 3e-46
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 180 3e-44
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 166 3e-40
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 164 1e-39
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 162 6e-39
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 150 2e-35
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 146 3e-34
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 146 3e-34
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 146 4e-34
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 145 6e-34
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 145 7e-34
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 143 3e-33
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 141 1e-32
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n... 140 2e-32
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp... 140 2e-32
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 139 4e-32
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 139 5e-32
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 137 1e-31
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 136 3e-31
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 135 6e-31
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 135 8e-31
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 134 1e-30
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 133 3e-30
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 132 4e-30
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 132 4e-30
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 131 1e-29
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 129 4e-29
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 128 7e-29
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 128 9e-29
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 128 9e-29
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 127 2e-28
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 124 1e-27
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 124 1e-27
UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide S-succinyltra... 122 8e-27
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 122 8e-27
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ... 120 3e-26
UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n... 119 4e-26
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 117 2e-25
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n... 115 7e-25
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 113 3e-24
UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n... 111 1e-23
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 111 1e-23
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 111 1e-23
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 107 1e-22
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 87 3e-16
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom... 85 1e-15
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 85 1e-15
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 85 1e-15
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 84 3e-15
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario... 82 1e-14
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra... 81 2e-14
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 81 2e-14
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 79 1e-13
UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC ... 75 1e-12
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera... 74 2e-12
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 74 3e-12
UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 73 4e-12
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 73 5e-12
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 73 6e-12
UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue ac... 72 8e-12
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 71 2e-11
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ... 71 3e-11
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 70 3e-11
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 69 6e-11
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 69 6e-11
UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase comp... 69 6e-11
UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma j... 69 6e-11
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 69 8e-11
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=... 68 1e-10
UniRef50_Q4E6V7 Cluster: Putative uncharacterized protein; n=1; ... 68 1e-10
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 68 2e-10
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 67 3e-10
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 67 3e-10
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 67 3e-10
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 66 4e-10
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 66 5e-10
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 66 5e-10
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n... 66 7e-10
UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of ... 65 1e-09
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 65 1e-09
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 65 1e-09
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 64 2e-09
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 64 2e-09
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 64 2e-09
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss... 64 3e-09
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 64 3e-09
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 63 4e-09
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;... 63 4e-09
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 63 5e-09
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 63 5e-09
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 62 7e-09
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 62 7e-09
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 62 9e-09
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 9e-09
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 62 1e-08
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 62 1e-08
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 61 2e-08
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 61 2e-08
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera... 61 2e-08
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 61 2e-08
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 61 2e-08
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 60 3e-08
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 3e-08
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 60 3e-08
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 60 4e-08
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 60 4e-08
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 60 4e-08
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 4e-08
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 4e-08
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 5e-08
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 6e-08
UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1; ... 59 6e-08
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ... 59 6e-08
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 8e-08
UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 58 1e-07
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 58 1e-07
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario... 58 1e-07
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 58 1e-07
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario... 58 1e-07
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 58 1e-07
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 58 1e-07
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 58 1e-07
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 58 1e-07
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 58 1e-07
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans... 58 2e-07
UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;... 57 3e-07
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 57 3e-07
UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2 comp... 57 3e-07
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,... 57 3e-07
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 57 3e-07
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 57 3e-07
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 57 3e-07
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 57 3e-07
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 57 3e-07
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 56 4e-07
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 56 4e-07
UniRef50_Q1AZ52 Cluster: Catalytic domain of components of vario... 56 4e-07
UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid dehydrog... 56 4e-07
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 56 4e-07
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 56 4e-07
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans... 56 4e-07
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 56 4e-07
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 56 6e-07
UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2 com... 56 6e-07
UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1; ... 56 6e-07
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 56 6e-07
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo... 56 6e-07
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4... 56 8e-07
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 56 8e-07
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 55 1e-06
UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase e... 55 1e-06
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 55 1e-06
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 55 1e-06
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 55 1e-06
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 54 2e-06
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 54 2e-06
UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase, c... 54 2e-06
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 54 2e-06
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 54 3e-06
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 4e-06
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 53 4e-06
UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 4e-06
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ... 53 4e-06
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 53 4e-06
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 53 5e-06
UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 53 5e-06
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 53 5e-06
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 5e-06
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 52 7e-06
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 52 7e-06
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 52 7e-06
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans... 52 7e-06
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 52 1e-05
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 52 1e-05
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 52 1e-05
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 52 1e-05
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 52 1e-05
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla... 52 1e-05
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 52 1e-05
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 52 1e-05
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 52 1e-05
UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 51 2e-05
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario... 51 2e-05
UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1... 51 2e-05
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 51 2e-05
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 51 2e-05
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 51 2e-05
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 51 2e-05
UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 51 2e-05
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 50 3e-05
UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex dihydrol... 50 3e-05
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 50 4e-05
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 50 4e-05
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 50 4e-05
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 50 4e-05
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 50 4e-05
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh... 50 4e-05
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 50 4e-05
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 50 4e-05
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 50 5e-05
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 50 5e-05
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 50 5e-05
UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2... 50 5e-05
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 50 5e-05
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 50 5e-05
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 49 7e-05
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 49 7e-05
UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate... 49 9e-05
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 49 9e-05
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 49 9e-05
UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding pro... 49 9e-05
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera... 49 9e-05
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario... 48 1e-04
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 48 1e-04
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 48 2e-04
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 48 2e-04
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 48 2e-04
UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase co... 48 2e-04
UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n... 48 2e-04
UniRef50_Q14PE3 Cluster: Hypothetical dihydrolipoamide acetyltra... 48 2e-04
UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component, d... 47 3e-04
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;... 47 3e-04
UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2 comp... 47 3e-04
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 47 3e-04
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 47 4e-04
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 46 5e-04
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 46 5e-04
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 46 5e-04
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 46 6e-04
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 46 6e-04
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 46 6e-04
UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, compone... 46 6e-04
UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 46 8e-04
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 45 0.001
UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue succinyltra... 45 0.001
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog... 45 0.001
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 45 0.001
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 45 0.001
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q6XYS6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 44 0.003
UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2... 44 0.003
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 44 0.003
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 43 0.004
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 43 0.004
UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma j... 43 0.004
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ... 43 0.006
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 42 0.008
UniRef50_Q9SIT8 Cluster: Putative uncharacterized protein At2g13... 42 0.008
UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Eugl... 42 0.008
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 42 0.010
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 41 0.018
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 41 0.018
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 41 0.023
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 41 0.023
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 40 0.031
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ... 40 0.031
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 40 0.041
UniRef50_A2VSW6 Cluster: Outer membrane autotransporter barrel; ... 40 0.054
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 40 0.054
UniRef50_A5CEC1 Cluster: Putative uncharacterized protein; n=6; ... 39 0.072
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 39 0.072
UniRef50_Q744M7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.095
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 39 0.095
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 39 0.095
UniRef50_O00555 Cluster: Voltage-dependent P/Q-type calcium chan... 39 0.095
UniRef50_Q3ADI4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.13
UniRef50_Q1DJG4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 38 0.22
UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2 comp... 38 0.22
UniRef50_A4REY6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 37 0.29
UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 37 0.29
UniRef50_A0GGU8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.29
UniRef50_Q6CBR2 Cluster: Yarrowia lipolytica chromosome C of str... 37 0.29
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3... 37 0.38
UniRef50_Q4PB21 Cluster: Putative uncharacterized protein; n=1; ... 37 0.38
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 37 0.38
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf... 36 0.51
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su... 36 0.51
UniRef50_A6R9N6 Cluster: Predicted protein; n=24; Ajellomyces ca... 36 0.51
UniRef50_A6R5U3 Cluster: Predicted protein; n=10; Ajellomyces ca... 36 0.51
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 36 0.67
UniRef50_UPI0000DD8383 Cluster: PREDICTED: hypothetical protein;... 36 0.88
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 36 0.88
UniRef50_Q6QW20 Cluster: Putative uncharacterized protein; n=1; ... 36 0.88
UniRef50_Q08S44 Cluster: Putative uncharacterized protein; n=1; ... 36 0.88
UniRef50_A7DEP4 Cluster: Putative uncharacterized protein; n=1; ... 36 0.88
UniRef50_Q69K05 Cluster: CAX-interacting protein 4 (CAXIP4)-like... 36 0.88
UniRef50_Q013E2 Cluster: Chromosome 08 contig 1, DNA sequence; n... 36 0.88
UniRef50_Q7R5Q9 Cluster: GLP_487_22143_20965; n=1; Giardia lambl... 36 0.88
UniRef50_Q173D7 Cluster: Putative uncharacterized protein; n=2; ... 36 0.88
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 35 1.2
UniRef50_Q3VZ74 Cluster: Putative uncharacterized protein precur... 35 1.2
UniRef50_Q8WT68 Cluster: Elongation factor-1 alpha; n=3; Endopte... 35 1.2
UniRef50_Q8ZV49 Cluster: Arsenite transport protein, conjectural... 35 1.2
UniRef50_A1FX86 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5
UniRef50_A5K5T0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5
UniRef50_Q9HZM8 Cluster: Ribonuclease E; n=27; Gammaproteobacter... 34 2.0
UniRef50_Q4Q3F8 Cluster: Splicing factor ptsr1 interacting prote... 34 2.0
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 34 2.0
UniRef50_UPI0001555B84 Cluster: PREDICTED: similar to PP239 prot... 34 2.7
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 34 2.7
UniRef50_A7P3H2 Cluster: Chromosome chr1 scaffold_5, whole genom... 34 2.7
UniRef50_Q7QX76 Cluster: GLP_217_46197_51209; n=1; Giardia lambl... 34 2.7
UniRef50_P30373 Cluster: Zinc finger protein CKR1; n=2; Gallus g... 34 2.7
UniRef50_Q5RI63 Cluster: Novel protein; n=13; Danio rerio|Rep: N... 33 3.6
UniRef50_A3VGW1 Cluster: Putative uncharacterized protein; n=1; ... 33 3.6
UniRef50_A1SG60 Cluster: Peptidase C11, clostripain precursor; n... 33 3.6
UniRef50_Q4CZM2 Cluster: Putative uncharacterized protein; n=3; ... 33 3.6
UniRef50_Q5KGC9 Cluster: Putative uncharacterized protein; n=1; ... 33 3.6
UniRef50_Q1E5Y0 Cluster: Putative uncharacterized protein; n=1; ... 33 3.6
UniRef50_A6RFJ6 Cluster: Predicted protein; n=6; Ajellomyces cap... 33 3.6
UniRef50_UPI000065EE29 Cluster: Homolog of Homo sapiens "CTD-bin... 33 4.7
UniRef50_UPI0000F32593 Cluster: UPI0000F32593 related cluster; n... 33 4.7
UniRef50_A7BMP4 Cluster: Putative uncharacterized protein; n=1; ... 33 4.7
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp... 33 4.7
UniRef50_Q7RHM7 Cluster: Cyclophilin-RNA interacting protein; n=... 33 4.7
UniRef50_Q17JW4 Cluster: Pnuts protein; n=2; Fungi/Metazoa group... 33 4.7
UniRef50_Q0IER5 Cluster: Putative uncharacterized protein; n=1; ... 33 4.7
UniRef50_UPI0000F212F9 Cluster: PREDICTED: hypothetical protein;... 33 6.2
UniRef50_Q3WG61 Cluster: Erythronolide synthase; n=1; Frankia sp... 33 6.2
UniRef50_Q1QL19 Cluster: Putative uncharacterized protein precur... 33 6.2
UniRef50_A0T5S8 Cluster: Putative uncharacterized protein; n=3; ... 33 6.2
UniRef50_Q0JGY9 Cluster: Os01g0895300 protein; n=1; Oryza sativa... 33 6.2
UniRef50_Q38CJ3 Cluster: Putative uncharacterized protein; n=1; ... 33 6.2
UniRef50_A7AWZ5 Cluster: DEAD/DEAH box helicase and helicase con... 33 6.2
UniRef50_Q5KAL3 Cluster: Putative uncharacterized protein; n=1; ... 33 6.2
UniRef50_A3LT76 Cluster: Phosphatidylinositol kinase; n=1; Pichi... 33 6.2
UniRef50_Q9HWX4 Cluster: Riboflavin biosynthesis protein ribAB [... 33 6.2
UniRef50_Q6KC79 Cluster: Nipped-B-like protein; n=75; Deuterosto... 33 6.2
UniRef50_UPI00015B4CDB Cluster: PREDICTED: similar to ENSANGP000... 32 8.2
UniRef50_UPI00015B42FD Cluster: PREDICTED: similar to ENSANGP000... 32 8.2
UniRef50_UPI0000E49D1D Cluster: PREDICTED: similar to MGC83832 p... 32 8.2
UniRef50_Q3JUL6 Cluster: 200 kDa antigen p200, putative; n=3; Bu... 32 8.2
UniRef50_Q3JSX0 Cluster: Putative uncharacterized protein; n=1; ... 32 8.2
UniRef50_Q30Z91 Cluster: Cation ABC transporter, periplasmc-bind... 32 8.2
UniRef50_Q8RTM3 Cluster: HP790-like protein; n=3; Campylobactera... 32 8.2
UniRef50_A0UED9 Cluster: 200 kDa antigen p200, putative; n=2; Bu... 32 8.2
UniRef50_A0JZU9 Cluster: Catalytic domain of components of vario... 32 8.2
UniRef50_Q00XJ5 Cluster: EXTN_SORBI Extensin; n=1; Ostreococcus ... 32 8.2
UniRef50_Q00VW1 Cluster: Chromosome 14 contig 1, DNA sequence; n... 32 8.2
UniRef50_Q7RG66 Cluster: Stress responsive gene 6, Srg6; n=4; Pl... 32 8.2
UniRef50_Q6GYB0 Cluster: Splice factor; n=1; Toxoplasma gondii|R... 32 8.2
UniRef50_Q4UG80 Cluster: Ubiquitin-activating enzyme e1, putativ... 32 8.2
UniRef50_O44772 Cluster: Putative uncharacterized protein; n=2; ... 32 8.2
UniRef50_P16893 Cluster: Thrombospondin-related anonymous protei... 32 8.2
UniRef50_Q8NAV1 Cluster: Pre-mRNA-splicing factor 38A; n=34; Euk... 32 8.2
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 220 bits (537), Expect = 2e-56
Identities = 103/147 (70%), Positives = 128/147 (87%)
Frame = +2
Query: 62 RHAQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEI 241
+HAQ++E A V++PPQDY++EI GTRTEQRVKMNR R RIA+RLKDAQNTNAMLTTFNEI
Sbjct: 227 KHAQSLEGAKVQLPPQDYTREIIGTRTEQRVKMNRMRLRIAERLKDAQNTNAMLTTFNEI 286
Query: 242 DMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVD 421
DMS ++ FRK + ++F KK+ +KLG MSPF+ A+A AL DQPVVNAVI+ +I+YRDYVD
Sbjct: 287 DMSALIDFRKSNQESFQKKYGLKLGFMSPFIAASAYALKDQPVVNAVIDGTDIVYRDYVD 346
Query: 422 ISVAVATPKGLVVPVIRNVQNMTYADI 502
ISVAVATPKGLVVPV+R+V+N +A+I
Sbjct: 347 ISVAVATPKGLVVPVLRSVENKNFAEI 373
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 186 bits (453), Expect = 3e-46
Identities = 97/146 (66%), Positives = 112/146 (76%), Gaps = 3/146 (2%)
Frame = +2
Query: 74 AIETATVKVPPQDYSKEIA-GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMS 250
AI+ + P +++ A G RTE RVKMNR R RIAQRLK+AQNT AMLTTFNE+DMS
Sbjct: 206 AIKPSVAAASPAAHAEGAAKGVRTESRVKMNRMRLRIAQRLKEAQNTCAMLTTFNEVDMS 265
Query: 251 HIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDI 424
+I RK + D F KKH+IKLG MS FVKAAA AL DQP VN VI++ EI+YRDYVDI
Sbjct: 266 NISEMRKTYKDAFLKKHNIKLGFMSAFVKAAAYALADQPAVNGVIDDTTKEIVYRDYVDI 325
Query: 425 SVAVATPKGLVVPVIRNVQNMTYADI 502
SVAVATPKGLVVPVIRNV+ M +ADI
Sbjct: 326 SVAVATPKGLVVPVIRNVEGMNFADI 351
>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=48;
Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor - Homo
sapiens (Human)
Length = 453
Score = 180 bits (437), Expect = 3e-44
Identities = 88/126 (69%), Positives = 105/126 (83%), Gaps = 2/126 (1%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G R+E R KMNR RQRIAQRLK+AQNT AMLTTFNEIDMS+I R +H + F KKH++K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
LG MS FVKA+A AL +QPVVNAVI++ E++YRDY+DISVAVATP+GLVVPVIRNV+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 485 MTYADI 502
M +ADI
Sbjct: 338 MNFADI 343
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 166 bits (404), Expect = 3e-40
Identities = 77/122 (63%), Positives = 99/122 (81%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
RTE R +++ RQRI QRLKD+QNT A+L TFNE+DMS++M R K+ + F KKH++KLG
Sbjct: 333 RTETRQPLSKMRQRIGQRLKDSQNTYALLPTFNEVDMSNVMEIRNKYQEQFQKKHNVKLG 392
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
MS FVKAA AL QP+VNAVI+ EI+YR+YVDISVAVATP GL+VPV+RN +NM++A
Sbjct: 393 FMSFFVKAATAALQQQPIVNAVIDGKEIVYRNYVDISVAVATPTGLMVPVLRNTENMSFA 452
Query: 497 DI 502
D+
Sbjct: 453 DV 454
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 164 bits (399), Expect = 1e-39
Identities = 79/134 (58%), Positives = 101/134 (75%)
Frame = +2
Query: 140 TEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGL 319
+E RVKM R RQR AQRLKD+QNT AMLTTFNE+DMS +M RK + D F KKH +K G
Sbjct: 209 SETRVKMTRIRQRTAQRLKDSQNTAAMLTTFNELDMSALMNMRKTYKDEFEKKHGVKFGF 268
Query: 320 MSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
MS FVKA+ AL +QP+VNA +EEN+I+Y + V+I+VAV+ P+GLVVPVIRN +N+++AD
Sbjct: 269 MSAFVKASTIALKEQPIVNASVEENDIVYHNNVNINVAVSAPRGLVVPVIRNCENLSFAD 328
Query: 500 IRAHHSWASGKSEN 541
I SG + N
Sbjct: 329 IEKEIGRLSGLARN 342
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 162 bits (393), Expect = 6e-39
Identities = 76/120 (63%), Positives = 97/120 (80%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+RV M R R+R+A RLKD+QNT A+LTTFNE+DM+++M R ++ D F +KH +KLGLM
Sbjct: 235 ERRVPMTRLRKRVATRLKDSQNTFALLTTFNEVDMTNLMKLRSQYKDAFLEKHGVKLGLM 294
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
S F+KAA +AL QPVVNAVI+ ++IIYRDYVDIS+AV T KGLVVPVIR+ M +ADI
Sbjct: 295 SGFIKAAVSALQHQPVVNAVIDGDDIIYRDYVDISIAVGTSKGLVVPVIRDADKMNFADI 354
>UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza
sativa|Rep: Os02g0514700 protein - Oryza sativa subsp.
japonica (Rice)
Length = 497
Score = 150 bits (364), Expect = 2e-35
Identities = 73/120 (60%), Positives = 94/120 (78%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+RV M R R+RIA RLKD+QNT AML TFNE+DM+++M + D F +KH +KLGLM
Sbjct: 268 ERRVPMPRLRKRIANRLKDSQNTFAMLITFNEVDMTNLMKLLSDYKDQFVEKHGVKLGLM 327
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
S FVKAA +AL +QP+VNAVI+ ++IIYR+Y+DISVAV T KGLVV VI ++ M +ADI
Sbjct: 328 SCFVKAAVSALQNQPIVNAVIDGDDIIYREYIDISVAVGTSKGLVVLVIHDIDAMNFADI 387
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 146 bits (354), Expect = 3e-34
Identities = 73/136 (53%), Positives = 98/136 (72%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHL 280
P + G R E+RVKM+R RQRIAQRLK+AQNT AMLTTFNE+DM+ +MA R ++
Sbjct: 203 PAAQLPPAVEGPR-EERVKMSRLRQRIAQRLKEAQNTAAMLTTFNEVDMTAVMALRSQYK 261
Query: 281 DTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVV 460
+ F K++ +LG MS FVKAA +AL + P VNA I+ NEI++++Y DI VAV +P+GLVV
Sbjct: 262 EVFEKRNHARLGFMSFFVKAAISALQEFPAVNAEIQGNEIVFKNYYDIGVAVGSPQGLVV 321
Query: 461 PVIRNVQNMTYADIRA 508
PV+R M+ A I +
Sbjct: 322 PVLRGADAMSLAGIES 337
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 146 bits (354), Expect = 3e-34
Identities = 74/125 (59%), Positives = 96/125 (76%)
Frame = +2
Query: 128 AGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSI 307
A RT+ V+++ R+RIA RLK +QNT AMLTTFNEIDM+ + R K+ D F K+H +
Sbjct: 155 ADPRTKS-VRISSMRRRIADRLKASQNTCAMLTTFNEIDMTPLFQLRDKYKDEFHKRHDV 213
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
KLGLMSPFVKA+A AL D P+VNA ++ I Y ++VDI++AVATP+GLVVPVIR+VQNM
Sbjct: 214 KLGLMSPFVKASAIALKDVPIVNASFGKDTIDYHEFVDIAIAVATPRGLVVPVIRDVQNM 273
Query: 488 TYADI 502
A+I
Sbjct: 274 NLANI 278
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 146 bits (353), Expect = 4e-34
Identities = 69/138 (50%), Positives = 99/138 (71%)
Frame = +2
Query: 122 EIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH 301
++ +RT +RVKM R R+ IAQRLKD+QN A+L+TFNE+DM ++ RKK+ + F KKH
Sbjct: 189 DVKASRTIERVKMTRLRRTIAQRLKDSQNNAAILSTFNEVDMFNVSELRKKYKEEFEKKH 248
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQ 481
IKLG MS FVKAA AL + P++NA ++ +I+Y +Y DI VAV+T GLVVP+IRN +
Sbjct: 249 EIKLGFMSFFVKAATAALQELPIINAQVDGYDILYHNYCDIGVAVSTNSGLVVPIIRNAE 308
Query: 482 NMTYADIRAHHSWASGKS 535
++++A+I S K+
Sbjct: 309 HLSFAEIEMEISQLGKKA 326
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 145 bits (352), Expect = 6e-34
Identities = 72/122 (59%), Positives = 86/122 (70%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
RTE RVKMNR R RIA+RLK++QNT A LTTFNE+DMS +M RK + D KK K G
Sbjct: 233 RTETRVKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMRKLYKDEIIKKTGTKFG 292
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
M F KA A D P VN IE ++I+YRDY DISVAVATPKGLV PV+RN ++++
Sbjct: 293 FMGLFSKACTLAAKDIPAVNGAIEGDQIVYRDYTDISVAVATPKGLVTPVVRNAESLSVL 352
Query: 497 DI 502
DI
Sbjct: 353 DI 354
>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex,
mitochondrial - Coccidioides immitis
Length = 484
Score = 145 bits (351), Expect = 7e-34
Identities = 76/128 (59%), Positives = 90/128 (70%), Gaps = 4/128 (3%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G R E+RVKMNR R RIA+RLK +QNT A LTTFNE+DMS +M FRK + + KK IK
Sbjct: 248 GNRDERRVKMNRMRLRIAERLKQSQNTAASLTTFNEVDMSSLMEFRKLYKEDILKKTGIK 307
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIE----ENEIIYRDYVDISVAVATPKGLVVPVIRNV 478
LG MS F +A A+ + P VNA IE + I+YRDYVDISVAVAT KGLV PV+RNV
Sbjct: 308 LGFMSAFARACVLAMKEVPAVNASIEGPNGGDTIVYRDYVDISVAVATEKGLVTPVVRNV 367
Query: 479 QNMTYADI 502
+NM I
Sbjct: 368 ENMDLTTI 375
>UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=79; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bartonella quintana (Rochalimaea quintana)
Length = 410
Score = 143 bits (346), Expect = 3e-33
Identities = 67/120 (55%), Positives = 89/120 (74%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+RV+M + RQ IA+RLKDAQNT AMLTTFNE+DMS +M RK++ D F KKH +KLG M
Sbjct: 181 EERVRMTKLRQTIARRLKDAQNTAAMLTTFNEVDMSAVMDLRKRYKDLFEKKHGVKLGFM 240
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
F KA +AL + P VNA I+ +I+Y++YV+ +AV T KGLVVPV+R+ M+ A+I
Sbjct: 241 GFFTKAVCHALKEFPTVNAEIDGTDIVYKNYVNAGIAVGTDKGLVVPVVRDADQMSLAEI 300
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 141 bits (341), Expect = 1e-32
Identities = 66/122 (54%), Positives = 90/122 (73%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R EQRV M+R R RIA+RL ++Q TNA+LTTFNE++M +M R K+ D F K+H +KLG
Sbjct: 194 RPEQRVPMSRLRARIAERLLESQQTNAILTTFNEVNMQPVMDLRAKYKDKFEKEHGVKLG 253
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
MS FVKAA +AL P+VNA I+ N+I+Y Y DI +AV +P+GLVVP++RN ++ A
Sbjct: 254 FMSFFVKAAVHALKKFPLVNASIDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQLSLA 313
Query: 497 DI 502
+I
Sbjct: 314 EI 315
>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
- Aspergillus oryzae
Length = 448
Score = 140 bits (340), Expect = 2e-32
Identities = 67/125 (53%), Positives = 92/125 (73%), Gaps = 1/125 (0%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G+R+E +VKM+R R R A+RLK++QNT A LTTFNE DMS IMA R ++ D +KH +K
Sbjct: 215 GSRSETKVKMSRMRLRTAERLKESQNTAAFLTTFNEADMSKIMALRSQNKDDVLQKHGVK 274
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEENE-IIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
LG M P +A+A AL + P +NA IE ++ I++ DY+D+SVAVATPKGLV PV+RN++
Sbjct: 275 LGFMGPVARASALALREIPAINASIENDDTIVFHDYIDLSVAVATPKGLVTPVLRNMERQ 334
Query: 488 TYADI 502
+I
Sbjct: 335 GIVEI 339
>UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase
component; n=6; Anaplasmataceae|Rep: Dihydrolipoamide
acetyltransferase component - Anaplasma marginale
(strain St. Maries)
Length = 437
Score = 140 bits (339), Expect = 2e-32
Identities = 73/136 (53%), Positives = 96/136 (70%), Gaps = 3/136 (2%)
Frame = +2
Query: 98 VPPQDYSKEIAGTRT---EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFR 268
VP Q E+ G + E+RVKM++ RQ IA RLK++QNT A L+TFNE+DMS +MA R
Sbjct: 190 VPQQRVYDEVDGVISVPGERRVKMSKIRQVIASRLKESQNTAATLSTFNEVDMSAVMALR 249
Query: 269 KKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPK 448
K+ + F KK+ +KLG MS F++A AL + PV+NA I +EIIYRDY +I VAV T K
Sbjct: 250 GKYKEGFEKKYEVKLGFMSFFIRAVVLALREIPVINAEISGDEIIYRDYCNIGVAVGTDK 309
Query: 449 GLVVPVIRNVQNMTYA 496
GLVVPVIR + M++A
Sbjct: 310 GLVVPVIRGAETMSFA 325
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 139 bits (337), Expect = 4e-32
Identities = 66/120 (55%), Positives = 88/120 (73%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+RV+M + RQ IA+RLK+AQ+T AMLTTFNE+DMS +MA R K+ D F KKH +KLG M
Sbjct: 195 EERVRMTKLRQTIARRLKEAQSTAAMLTTFNEVDMSAVMALRTKYKDVFEKKHGVKLGFM 254
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
F KA +AL + P VNA I+ +IIY+++ + VAV T KGLVVPV+R+ M+ A+I
Sbjct: 255 GFFTKAVTHALKEIPAVNAEIDGTDIIYKNFAHVGVAVGTEKGLVVPVVRDADQMSIAEI 314
>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 415
Score = 139 bits (336), Expect = 5e-32
Identities = 72/134 (53%), Positives = 92/134 (68%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHL 280
P + E GTRTE KM+R R+ IAQRL DAQ A+L+TFNEIDMS +M RK+H
Sbjct: 175 PTPATAPEARGTRTE---KMSRLRRTIAQRLVDAQQEAAILSTFNEIDMSAVMNLRKQHK 231
Query: 281 DTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVV 460
D F KH I LG MS F KA A AL + P++NA ++ N IIY D+VD+ +AV+TPKGLVV
Sbjct: 232 DEFKDKHEIGLGFMSFFTKATAIALKEFPIMNAQVDGNSIIYHDFVDMGIAVSTPKGLVV 291
Query: 461 PVIRNVQNMTYADI 502
PVIR+ + ++ I
Sbjct: 292 PVIRDCDQLNFSGI 305
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 137 bits (332), Expect = 1e-31
Identities = 66/119 (55%), Positives = 90/119 (75%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
QRV+M+R R+ IAQRLKD+QNT A+LTTFNEIDMS ++A R ++ + F KKH +KLG MS
Sbjct: 173 QRVRMSRLRKTIAQRLKDSQNTAAILTTFNEIDMSKVIALRNQYKEEFEKKHLVKLGFMS 232
Query: 326 PFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
FVKA AL P VNA I+ ++++Y++Y DI VAV T +GLVVPV+R+ M +A++
Sbjct: 233 FFVKATIEALKLIPSVNAEIDGDDLVYKNYYDIGVAVGTEQGLVVPVVRDADKMGFAEV 291
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 136 bits (330), Expect = 3e-31
Identities = 65/122 (53%), Positives = 88/122 (72%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R E+RV M R R RIA+RL +Q+T A+LTTFNE++M IM R ++ D+F K+H IKLG
Sbjct: 194 RLEKRVPMTRLRMRIAERLVQSQSTAAILTTFNEVNMQAIMDLRARYKDSFEKEHGIKLG 253
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
S FVKA AL P++NA ++ N+IIY DY DI +AVA+P+GLVVP+IR+ +T+A
Sbjct: 254 FTSFFVKAVVAALKKFPIINASVDGNDIIYHDYYDIGIAVASPRGLVVPIIRDADKLTFA 313
Query: 497 DI 502
I
Sbjct: 314 GI 315
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 135 bits (327), Expect = 6e-31
Identities = 67/145 (46%), Positives = 99/145 (68%)
Frame = +2
Query: 68 AQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
A A E+A P ++ R+E+RV M R R+R+A+RL +A+N+ AMLTTFNE++M
Sbjct: 153 APAKESAPAAAAPA--AQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNM 210
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDIS 427
IM RK++ + F K+H I+LG MS +VKA AL P VNA I+ ++++Y +Y D+S
Sbjct: 211 KPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVS 270
Query: 428 VAVATPKGLVVPVIRNVQNMTYADI 502
+AV+TP+GLV PV+R+V + ADI
Sbjct: 271 MAVSTPRGLVTPVLRDVDTLGMADI 295
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 135 bits (326), Expect = 8e-31
Identities = 61/120 (50%), Positives = 92/120 (76%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+RV M+R R++I++RL + Q T AMLTTFNEI+M +M +R + F KK+ +KLGLM
Sbjct: 112 EERVPMSRLRKKISERLLNVQQTTAMLTTFNEINMQAVMNYRHDFQNDFVKKYGVKLGLM 171
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
S FV+AA AL PV+NA+I+ ++++YR Y +I +AVA+P+GLVVP++RN + +++ADI
Sbjct: 172 SFFVRAAVAALRQFPVINAMIDGDDVVYRRYCNIGIAVASPRGLVVPILRNAETLSFADI 231
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 134 bits (325), Expect = 1e-30
Identities = 68/135 (50%), Positives = 93/135 (68%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
RTE+R++M R+RIA+RLK++QNT A+LTTFNE DMS + R + D F KK+ KLG
Sbjct: 1401 RTEKRIRMLPMRKRIAERLKESQNTCALLTTFNECDMSKAIVLRTELKDIFQKKYGCKLG 1460
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+S F+ A+ AL P VNA I+ +EI+Y++Y+DISVAVATP GL VPVIR+ QN
Sbjct: 1461 FVSLFLYASTLALKKMPQVNAYIDNDEIVYKNYIDISVAVATPNGLTVPVIRDCQNKNLP 1520
Query: 497 DIRAHHSWASGKSEN 541
+ S + K++N
Sbjct: 1521 QLELALSDIAAKAKN 1535
>UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable
dihydrolipoyllysine-residue succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial precursor - Schizosaccharomyces pombe
(Fission yeast)
Length = 452
Score = 133 bits (321), Expect = 3e-30
Identities = 66/129 (51%), Positives = 89/129 (68%), Gaps = 4/129 (3%)
Frame = +2
Query: 134 TRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKL 313
+R E RVKMNR R RIA+RLK++QN A LTTFNE DMS ++A RKK+ D K+ +K+
Sbjct: 217 SRNEDRVKMNRMRLRIAERLKESQNRAASLTTFNECDMSAVVALRKKYKDEILKETGVKI 276
Query: 314 GLMSPFVKAAANALMDQPVVNAVIE----ENEIIYRDYVDISVAVATPKGLVVPVIRNVQ 481
G MS F KA A+ P +N IE + ++YRD+ D+S+AVATPKGLV PVIRN +
Sbjct: 277 GFMSFFSKACTQAMKQIPAINGSIEGEGKGDTLVYRDFCDLSIAVATPKGLVTPVIRNAE 336
Query: 482 NMTYADIRA 508
+M+ +I +
Sbjct: 337 SMSLLEIES 345
>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 413
Score = 132 bits (320), Expect = 4e-30
Identities = 63/120 (52%), Positives = 82/120 (68%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+RVKM R RQ IA+RLK+ QNT AMLTTFNE+DM+ +M R + + F KKH +KLG M
Sbjct: 184 EERVKMTRLRQTIARRLKEVQNTAAMLTTFNEVDMTGVMTLRTHYKEVFEKKHGVKLGFM 243
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
F KA AL D P NA I+ ++IY++Y I +AV T KGLVVPV+R+ + A+I
Sbjct: 244 GFFTKACVQALKDIPAANAEIDGTDLIYKNYYHIGIAVGTDKGLVVPVVRDCDRKSIAEI 303
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 132 bits (320), Expect = 4e-30
Identities = 61/122 (50%), Positives = 88/122 (72%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
+ RVKM R RQRIA+RL D++N AMLTTF+E++M I+ RKK+ + F KKH++++G
Sbjct: 189 KVTNRVKMTRLRQRIAERLLDSKNNTAMLTTFHEVNMKPIILLRKKYGEDFEKKHNVRIG 248
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
MS FVKA AL + P +NA I++ +I++ DIS+A++TP+GL+ PVIRN MT A
Sbjct: 249 FMSFFVKAVIQALKNFPEINAYIDQTDIVFYKNFDISIAISTPRGLITPVIRNADTMTMA 308
Query: 497 DI 502
+I
Sbjct: 309 EI 310
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 131 bits (317), Expect = 1e-29
Identities = 67/139 (48%), Positives = 90/139 (64%), Gaps = 1/139 (0%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G R+E+ M+ R+ IA RL AQ T A+LTTFNEI+M+ +MA R K+ D F KKH +K
Sbjct: 202 GYRSEEVKPMSMLRRTIASRLVQAQQTAALLTTFNEINMAPVMAIRSKYKDAFAKKHGVK 261
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMT 490
LG MS F KA AL P VNA I + ++YR+Y DI +A+ KGLVVPV+RNV+ M+
Sbjct: 262 LGFMSFFAKATVEALRRYPAVNAEIRGDSMVYRNYQDIGIAIGGGKGLVVPVLRNVERMS 321
Query: 491 YADIRAH-HSWASGKSENR 544
+A++ +A ENR
Sbjct: 322 FAEVEGSIAEYARLAGENR 340
>UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Chloroflexus|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Chloroflexus aggregans DSM 9485
Length = 469
Score = 129 bits (312), Expect = 4e-29
Identities = 63/134 (47%), Positives = 87/134 (64%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHL 280
PP G R E+R +++R R IA+RL +AQ+T AMLTTFNE+DMS +MA R +H
Sbjct: 226 PPATPVMTTNGDRREERQRLSRRRLTIARRLVEAQHTAAMLTTFNEVDMSAVMALRARHK 285
Query: 281 DTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVV 460
D+F ++H + LG MS F KA AL P+VNA I+ E++ + Y DI +AV +GLVV
Sbjct: 286 DSFKERHGVSLGYMSFFTKAVVGALKAFPMVNAEIQGEEVVIKYYYDIGIAVGVDEGLVV 345
Query: 461 PVIRNVQNMTYADI 502
PV+R+ T+A I
Sbjct: 346 PVVRDADRKTFAQI 359
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 128 bits (310), Expect = 7e-29
Identities = 64/135 (47%), Positives = 92/135 (68%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R+ +RVKM R R++I++RL +N A LTTFNE++M I+ R+K+ + F +KH IKLG
Sbjct: 179 RSIKRVKMTRLRKKISERLLSTKNNTASLTTFNEVNMQSILNLRRKYGELFKQKHGIKLG 238
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
LMS +VKA AL P +NA I+ +EIIY +Y DIS+A++TP+GLV PV++N M+ A
Sbjct: 239 LMSFYVKAVIEALKIFPEINASIDNDEIIYYNYFDISIAISTPRGLVTPVLKNADLMSMA 298
Query: 497 DIRAHHSWASGKSEN 541
+I S K +N
Sbjct: 299 EIEIKIKDFSEKGKN 313
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 128 bits (309), Expect = 9e-29
Identities = 59/122 (48%), Positives = 88/122 (72%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R+E+RV M R R+ +A RL +A+N+ AMLTTFNE++M IM RK++ D F +H I+LG
Sbjct: 171 RSEKRVPMTRLRKTVANRLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGDQFEARHGIRLG 230
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
MS +VKA AL P +NA I+ ++I+Y +Y DIS+AV+TP+GLV PV+++ + +A
Sbjct: 231 FMSFYVKAVTEALKRYPEINASIDGDDIVYHNYFDISMAVSTPRGLVTPVLKDCDTLGFA 290
Query: 497 DI 502
D+
Sbjct: 291 DV 292
>UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (E2)
of 2-oxoglutarate dehydrogenase; n=6; cellular
organisms|Rep: Dihydrolipoamide succinyl transferase
(E2) of 2-oxoglutarate dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 369
Score = 128 bits (309), Expect = 9e-29
Identities = 63/121 (52%), Positives = 86/121 (71%), Gaps = 1/121 (0%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS-IKLGL 319
E+RV M+R RQ IA+ LK AQNT A+LTTFNEIDMS A R ++ + F KKH +LG
Sbjct: 139 ERRVPMSRLRQTIARNLKAAQNTAAILTTFNEIDMSAAKALRAQYKEEFEKKHDGARLGF 198
Query: 320 MSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
MS F +A AL D P +NA IE +EI+YRD+V++ +AV T +GLVVPV+ + M++A+
Sbjct: 199 MSFFARAVVGALKDYPAINAQIEGDEIVYRDFVNLGIAVGTERGLVVPVLHDADQMSFAE 258
Query: 500 I 502
+
Sbjct: 259 L 259
>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=7; Flavobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Gramella forsetii (strain KT0803)
Length = 438
Score = 127 bits (306), Expect = 2e-28
Identities = 61/126 (48%), Positives = 86/126 (68%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
GTR E++ KM+ R+++A+RL A+N AMLTTFNE+DMS I RKK+ + F KH +
Sbjct: 197 GTRGEEKKKMSMFRRKLAERLVSAKNDTAMLTTFNEVDMSPIFELRKKYKEEFKDKHGVS 256
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMT 490
LG MS F A AL + P VN++I+ + I DY DIS+AV+ PKGL VPVIRN +N++
Sbjct: 257 LGFMSFFTLAVIRALDEYPAVNSMIDGDYQISYDYKDISIAVSGPKGLTVPVIRNAENLS 316
Query: 491 YADIRA 508
+ + +
Sbjct: 317 FRGVES 322
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 124 bits (300), Expect = 1e-27
Identities = 66/136 (48%), Positives = 88/136 (64%)
Frame = +2
Query: 95 KVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK 274
+VPP+ +A R M R+RIA + A+ AMLTTFNEIDMS + RK+
Sbjct: 200 RVPPRR-QVVLAPEELTVRKPMTPIRRRIADHMLQARLNTAMLTTFNEIDMSRLQEIRKQ 258
Query: 275 HLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGL 454
D F KKHS+ LG+MS F+KAAA AL + P +NA IE +EI+Y +Y+ I VAV +GL
Sbjct: 259 FRDLFQKKHSVSLGIMSFFLKAAAVALKELPELNAFIEGHEIVYHNYIHIGVAVGAERGL 318
Query: 455 VVPVIRNVQNMTYADI 502
VVPVIR+V + +AD+
Sbjct: 319 VVPVIRDVDKLGFADL 334
>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=4;
Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrococcus mobilis Nb-231
Length = 443
Score = 124 bits (299), Expect = 1e-27
Identities = 61/122 (50%), Positives = 82/122 (67%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R E+R M R RQRIA+RL +AQ AMLTTFNE +M IM+ R ++ + F + H IKLG
Sbjct: 212 RPERRAPMTRLRQRIAERLVEAQQNTAMLTTFNECNMQPIMSLRNRYKERFERYHGIKLG 271
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+MS FVK AL P VNA I+ +IIY Y DI +AV+T +GL+VPV+R+ + +A
Sbjct: 272 IMSFFVKTVIEALKRFPAVNASIDGKDIIYHGYYDIGIAVSTERGLLVPVLRDADQLGFA 331
Query: 497 DI 502
+I
Sbjct: 332 EI 333
>UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide
S-succinyltransferase, (2-oxogluturate dehydrogenase
complex E2 component), sucB; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Probable
dihydrolipoamide S-succinyltransferase, (2-oxogluturate
dehydrogenase complex E2 component), sucB -
Protochlamydia amoebophila (strain UWE25)
Length = 404
Score = 122 bits (293), Expect = 8e-27
Identities = 59/122 (48%), Positives = 82/122 (67%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R E R +++ RQ IA RL +AQ T AMLTTFNE+D+S I++ R+KH + F KK+ IKLG
Sbjct: 173 RQETRQPLSKIRQVIANRLIEAQQTMAMLTTFNEVDLSEIISLREKHQEIFIKKYGIKLG 232
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
MS FVKA +AL P VN+ +++ +I+ R Y DI +AV T +G VPV+R ++A
Sbjct: 233 FMSFFVKAVVSALKAFPTVNSYLDQQDIVERHYYDIGIAVGTERGTFVPVVRQCDQQSFA 292
Query: 497 DI 502
I
Sbjct: 293 QI 294
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 122 bits (293), Expect = 8e-27
Identities = 62/149 (41%), Positives = 93/149 (62%)
Frame = +2
Query: 95 KVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK 274
K PQ + + + + KM+R RQ IA+RL + Q T+AMLTTFNE+DM+ +M RK+
Sbjct: 171 KQQPQAQKAQQSFDKPVEVQKMSRRRQTIAKRLVEVQQTSAMLTTFNEVDMTAVMNLRKR 230
Query: 275 HLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGL 454
D F +++ +KLG MS F KA AL P++NA I+ +E+I + + DI +AVA +GL
Sbjct: 231 RKDQFFEQNEVKLGFMSFFTKAVVAALKKYPLLNAEIQGDELIVKKFYDIGIAVAAVEGL 290
Query: 455 VVPVIRNVQNMTYADIRAHHSWASGKSEN 541
VVPV+R+ +T+A I + K+ N
Sbjct: 291 VVPVVRDADRLTFAGIEKEIGELAKKARN 319
>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10947.1 - Gibberella zeae PH-1
Length = 442
Score = 120 bits (288), Expect = 3e-26
Identities = 62/149 (41%), Positives = 93/149 (62%), Gaps = 2/149 (1%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHL 280
P Q G R + KM+R R+ IA RLK +QNT A LTT E+DMS+++A+R K+
Sbjct: 198 PAQSSGAPNRGERVNLQEKMSRMRRTIAGRLKQSQNTCASLTTIQEVDMSNLIAWRAKYK 257
Query: 281 DTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIE-ENEII-YRDYVDISVAVATPKGL 454
+ ++H ++LG M F KA A P +NA I+ E EII Y DYVD+S+AV+ PKGL
Sbjct: 258 EEVAEEHGVRLGYMGAFTKATTIAAQKVPQINAQIDTEKEIITYHDYVDVSIAVSAPKGL 317
Query: 455 VVPVIRNVQNMTYADIRAHHSWASGKSEN 541
V PV+RN ++++ ++ + A+ K+ +
Sbjct: 318 VTPVLRNTESLSIVELERAVAAAAKKARD 346
>UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Succinyltransferase
- Chlamydia trachomatis
Length = 365
Score = 119 bits (287), Expect = 4e-26
Identities = 58/120 (48%), Positives = 82/120 (68%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E R M+ R+ I++RL + + +AMLTTFNEI M ++A RK+ + F K+ +KLG M
Sbjct: 137 ESRESMSAIRKTISRRLVQSLHDSAMLTTFNEIHMGPLIALRKERQEDFVAKYGVKLGFM 196
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
S FV+A ++L P VNA IE+NEI+YR Y DIS+A+ T +GLVVPVIRN ++ +I
Sbjct: 197 SFFVRAVVDSLKKYPRVNAYIEDNEIVYRHYYDISIAIGTDRGLVVPVIRNCDQLSSGEI 256
>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
succinyltransferase, putative - Babesia bovis
Length = 402
Score = 117 bits (282), Expect = 2e-25
Identities = 57/118 (48%), Positives = 87/118 (73%)
Frame = +2
Query: 149 RVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSP 328
+V+M R R+RI +RLK++Q T ML+TFNE DM IMA RK+ ++ K+ +KLG +S
Sbjct: 178 QVQMTRMRKRIGERLKESQQTTVMLSTFNECDMDAIMALRKELNES--GKYPVKLGYVSA 235
Query: 329 FVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
++KA+ AL+ P++N+ IE ++I+ + +VDISVAVATP GLVVPVIRN + ++ ++
Sbjct: 236 YMKASTMALLKMPIMNSYIEGDDIVTKHFVDISVAVATPTGLVVPVIRNCEGKSWIEL 293
>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Geobacter|Rep: Dihydrolipoamide succinyltransferase -
Geobacter metallireducens (strain GS-15 / ATCC 53774 /
DSM 7210)
Length = 418
Score = 115 bits (277), Expect = 7e-25
Identities = 55/118 (46%), Positives = 76/118 (64%)
Frame = +2
Query: 149 RVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSP 328
R M R+RIA+RL A+ AMLTTFNE D+ +M RKK+ + F KKH + LG MS
Sbjct: 191 RSPMTPIRKRIAERLLVARQQTAMLTTFNEADLGRVMELRKKYKEHFQKKHGVSLGFMSF 250
Query: 329 FVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
FVKA AL + P VN IE ++I++ Y I +A+ KGLVVPV+R+ +++A+I
Sbjct: 251 FVKACVEALKEYPAVNGSIEGDDIVFHHYYHIGIAIGAEKGLVVPVLRDADRLSFAEI 308
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 113 bits (272), Expect = 3e-24
Identities = 56/122 (45%), Positives = 79/122 (64%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R R ++ RQ +A+RL A+ AM TT NE D+S IM R ++ + F +++ IKLG
Sbjct: 166 RLSHREPLSPLRQTVARRLLAARQQTAMATTINEADLSRIMELRSQYGERFMERNGIKLG 225
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
LMS FVKA AL + PV+NA +EE I+Y+ + DI +AVAT +GLV PV+ N + +A
Sbjct: 226 LMSFFVKACVEALREFPVINARLEEEAIVYQHFYDIGIAVATDQGLVAPVLLNADRLNFA 285
Query: 497 DI 502
DI
Sbjct: 286 DI 287
>UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Thiobacillus denitrificans ATCC 25259|Rep:
Dihydrolipoamide succinyltransferase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 379
Score = 111 bits (267), Expect = 1e-23
Identities = 53/119 (44%), Positives = 81/119 (68%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+R M+R RQR+A+RL AQ+T AMLTTFNE++M + R++ F +H +KLG MS
Sbjct: 149 RREPMSRLRQRVAERLVAAQHTAAMLTTFNEVNMQPVNELRQRFKADFEVRHGVKLGYMS 208
Query: 326 PFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
FV+A AL P+VNA I+ N+I++ DI +A+++P+GLVVP++R Q ++ +I
Sbjct: 209 FFVRAVCRALEAFPIVNARIDGNDIVWHGDADIGIAISSPRGLVVPILRRAQQLSSDEI 267
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 111 bits (267), Expect = 1e-23
Identities = 51/122 (41%), Positives = 80/122 (65%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R +++ M+ R+ I++RL AMLTTFNE++M I++ R K+ D F K+ KLG
Sbjct: 167 RIFRKIAMSPLRKTISKRLLYTVKNTAMLTTFNEVNMQPIISIRNKYKDIFENKYKSKLG 226
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
MS +VK+ AL P +NA IE+ IIY DY DI++A++TP+GL+ P+++N N++
Sbjct: 227 FMSFYVKSVTQALKKFPEINASIEKKNIIYHDYYDINIAISTPRGLITPILKNTDNLSIY 286
Query: 497 DI 502
+I
Sbjct: 287 EI 288
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 111 bits (266), Expect = 1e-23
Identities = 58/120 (48%), Positives = 82/120 (68%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E RV + R R RIA+RLK AQ N MLTTFNE DMS + RK ++ + S KLG +
Sbjct: 231 ETRVPLTRMRMRIAERLKLAQTENVMLTTFNECDMSELTKVRKMLNES--GEVSCKLGFV 288
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
S F++A+ AL+ P++N+ I+ E++ ++YVDISVAVATP GL+VPVIRN + + ++
Sbjct: 289 SAFMRASTLALLKMPIMNSYIDGKEMVTKNYVDISVAVATPTGLLVPVIRNCEFKNWEEL 348
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 107 bits (258), Expect = 1e-22
Identities = 61/144 (42%), Positives = 87/144 (60%), Gaps = 1/144 (0%)
Frame = +2
Query: 74 AIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSH 253
A + T K+ Q+ SK + R KM+R ++ A++L + N AMLTTFNEIDM++
Sbjct: 176 AAKEETKKLTQQNPSKPVI------REKMSRRKKTAAKKLLEVSNNTAMLTTFNEIDMTN 229
Query: 254 IMAFRKKHLDTFTKKHS-IKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISV 430
+M RK+ + F K H KLG MS F KAA AL P VNA I+ +++I + Y DI V
Sbjct: 230 VMDLRKRKKEQFIKDHDGTKLGFMSFFTKAAVAALKKYPEVNAEIDGDDMITKQYYDIGV 289
Query: 431 AVATPKGLVVPVIRNVQNMTYADI 502
AV+T GL+VP +R+ +A+I
Sbjct: 290 AVSTEDGLLVPFVRDCDKKNFAEI 313
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
E2 component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 87.0 bits (206), Expect = 3e-16
Identities = 45/111 (40%), Positives = 67/111 (60%)
Frame = +2
Query: 155 KMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFV 334
KM+R R+ IAQR+K++ +A LTT E+D++ I R + D F KL + FV
Sbjct: 388 KMSRLRKVIAQRMKESLQNSAQLTTVIEVDVTKIARLRARAKDGFLATEGAKLTFLPFFV 447
Query: 335 KAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
KAA AL P +NA I+ I+Y ++S+AV TPKGL+ PVI++ ++
Sbjct: 448 KAAVEALKQHPSLNASIDGENIVYHGSENVSMAVDTPKGLITPVIKDAGDL 498
>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
Streptomyces coelicolor|Rep: Putative acyltransferase -
Streptomyces coelicolor
Length = 417
Score = 85.0 bits (201), Expect = 1e-15
Identities = 61/155 (39%), Positives = 82/155 (52%), Gaps = 3/155 (1%)
Frame = +2
Query: 68 AQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
A A A V+ P + + + G RT V M R R+ I LK A A LT+ E D+
Sbjct: 156 APAPAPAPVRAAPAEDASSLRG-RT---VAMTRIRRAIGNNLKKALLEQAQLTSTVEADV 211
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENE--IIYRDYVD 421
+ +M R + D F + +KL M FVKAAA AL PVVNA I E+E I Y D +
Sbjct: 212 TRLMRLRNRAKDGFLAREGLKLSPMPFFVKAAAQALKAHPVVNARINEDEGTITYFDSEN 271
Query: 422 ISVAVATPKGLVVPVIRNVQNMTYADI-RAHHSWA 523
I +AV T GL+ PV++ ++T A + RA H A
Sbjct: 272 IGIAVDTEAGLMTPVVKAAGDLTVAGLARAVHDLA 306
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 85.0 bits (201), Expect = 1e-15
Identities = 43/141 (30%), Positives = 87/141 (61%), Gaps = 1/141 (0%)
Frame = +2
Query: 122 EIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH 301
+++ + +++ ++M+R R+ IAQR+ D++ T+A +T+F E DM++I+ +R+K+ + +K
Sbjct: 192 QVSISASDEIIEMDRMRKMIAQRMVDSKKTSAHVTSFVEADMTNIVLWREKNKQAYREKF 251
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNV 478
+ F++A A A+ D P++N I+ ++II + ++I +AVA P G L+VPVIR
Sbjct: 252 GESITYTPFFIEAIAKAIRDFPMINISIDGDKIIKKKDINIGMAVALPSGNLIVPVIRKA 311
Query: 479 QNMTYADIRAHHSWASGKSEN 541
+ I + + ++ N
Sbjct: 312 DQLNLVGISKQVNDLANRARN 332
>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Tropheryma whipplei|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 84.6 bits (200), Expect = 1e-15
Identities = 41/116 (35%), Positives = 70/116 (60%)
Frame = +2
Query: 149 RVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSP 328
R+KM+R R IA+R + A L+T E+D++ I+ +R + F + + L ++
Sbjct: 232 RIKMSRLRNIIAERAVHSMQNTAQLSTVIEVDLTRIVDYRNSIKEKFKEAEGVNLTVLPF 291
Query: 329 FVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+ A AL PV+N+ I +++I++ DY +IS+AV T +GL+ PVI+N +MT A
Sbjct: 292 IINATVQALRKYPVINSHIVDDQIVFPDYENISLAVDTERGLLTPVIKNAGDMTVA 347
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 83.8 bits (198), Expect = 3e-15
Identities = 44/113 (38%), Positives = 70/113 (61%), Gaps = 1/113 (0%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
++M+R R+ IAQR+ D++ + +TTF E D+++I+ +R K F +KH K+ F
Sbjct: 224 IEMDRMRKMIAQRMVDSKRISPHVTTFVEADVTNIVMWRNKVKKEFQQKHGEKITFTPIF 283
Query: 332 VKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNM 487
++A A L D P+VN+ IE II + ++I +A A P G L+VPVI+N M
Sbjct: 284 IEAIAKTLGDFPLVNSSIEGENIIVKKDINIGMATALPSGNLIVPVIKNADQM 336
>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=18; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 597
Score = 81.8 bits (193), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 2/119 (1%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
VKM+R R+ IA R+ D+ T+A LT E+D+++I R + F + +KL + F
Sbjct: 367 VKMSRLRKIIATRMVDSLQTSAQLTQVVEVDVTNIARLRDEAKADFLSREGVKLSYLPFF 426
Query: 332 VKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
KAA +AL P +NA I E E+ Y D ++++AV T KGL+ PVI++ +++ A +
Sbjct: 427 AKAAIDALKHHPALNATIDTEAGEVTYYDRENLAIAVDTEKGLITPVIKDAGDLSIAGL 485
>UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 367
Score = 81.0 bits (191), Expect = 2e-14
Identities = 46/121 (38%), Positives = 73/121 (60%), Gaps = 2/121 (1%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G+ TE K+ R R+ IA+R+ ++ T A LTT E+D++ I R H D F ++ IK
Sbjct: 132 GSTTE---KLPRIRRTIAKRMVESLQTAAQLTTVLEVDVTAIARLRATHKDAFLQRTGIK 188
Query: 311 LGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
L + F +AA +AL + V+NA + + E+ Y D+ + +AV + KGL+VPVIR+ Q
Sbjct: 189 LSFLPFFAQAAVDALAEHRVLNASLNTDVTEVTYYDHCHLGMAVDSAKGLMVPVIRDAQQ 248
Query: 485 M 487
+
Sbjct: 249 L 249
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 81.0 bits (191), Expect = 2e-14
Identities = 47/143 (32%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Frame = +2
Query: 83 TATVKVPPQDYSKEIAG-TRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIM 259
T PP + ++ G R E+ K+ R+ IA ++ + T +T F++ D++ +
Sbjct: 224 TTPAVTPPGEQGEDAYGPVRIEKMAKI---RKTIANQMVMSWTTAPRVTNFDDADVTALE 280
Query: 260 AFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVA 433
A R++ D + +KL MS VKA A AL + P +NA+I E N+++Y++YV++ +A
Sbjct: 281 ALRQQSKDDYASA-GVKLTSMSFLVKAVALALRNNPAINALIDMENNQVVYKEYVNVGIA 339
Query: 434 VATPKGLVVPVIRNVQNMTYADI 502
V + +GLVVP IRN + +I
Sbjct: 340 VDSERGLVVPNIRNADRLAIPEI 362
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 78.6 bits (185), Expect = 1e-13
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +2
Query: 149 RVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSP 328
RVK++ R+ +A+R+ D+ + +T EIDMS + R + L ++ +L
Sbjct: 211 RVKLSGLRKVVAKRMVDSAFSAPHVTITTEIDMSSTIKIRSQLLGMIEQETGYRLSYTEI 270
Query: 329 FVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
+KA A+ALM P +NA ENEI+Y + V I +AVA GLVVPV+++V A +
Sbjct: 271 VMKAVAHALMSHPTINASFFENEIVYHEDVHIGLAVAVEGGLVVPVVKHVDKKGLAQLTN 330
Query: 509 H-HSWASGKSENR*AHDRKNG 568
+ A +NR + + +G
Sbjct: 331 ECKTVAMAARDNRLSQEMMSG 351
>UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC
14580|Rep: AcoC - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 377
Score = 74.9 bits (176), Expect = 1e-12
Identities = 41/152 (26%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Frame = +2
Query: 116 SKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTK 295
+K+ A E+R + R+ IA R+ ++ +A LT + D++ + +K+ +T
Sbjct: 141 NKQAAKAEAEERPPASPMRKTIAARMTESLQNSAQLTITMKADITKLTVLQKQLNETAQS 200
Query: 296 KHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRN 475
++ KL + +AA +L+D P +N+V ++ + ++V + VA A +GL VPVIR+
Sbjct: 201 RYDTKLTITDFAARAAVFSLLDHPAMNSVYQDGRLATFEHVHLGVAAALDEGLAVPVIRH 260
Query: 476 VQNMTYADIRAHHSWASGKS-ENR*AHDRKNG 568
+ + ++ W + K+ E R HD G
Sbjct: 261 AERLPLIELAKKIKWYAKKAREGRLLHDEIEG 292
>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Salinibacter ruber DSM
13855|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Salinibacter ruber (strain
DSM 13855)
Length = 639
Score = 74.1 bits (174), Expect = 2e-12
Identities = 42/149 (28%), Positives = 84/149 (56%), Gaps = 1/149 (0%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHL 280
P + ++ G R E + M+R R+ A+ + ++ T+A +T+F E D++ ++ R+ +
Sbjct: 391 PSDEELRQQYGDRIEVQ-PMDRMRKMTAEHMVRSKATSAHVTSFAEADVTGLVQLREANK 449
Query: 281 DTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVAT-PKGLV 457
+ F ++ +KL FVKAA AL + P++NA +E ++I+ + + +AVA KGL+
Sbjct: 450 EAFREREGVKLTYTPFFVKAAVEALREHPLLNASVEGDKIVIKHDFHVGIAVAIGNKGLL 509
Query: 458 VPVIRNVQNMTYADIRAHHSWASGKSENR 544
PVIRN + + + + + ++ N+
Sbjct: 510 APVIRNAGDYNVSGLARKAANVAERARNK 538
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 73.7 bits (173), Expect = 3e-12
Identities = 39/114 (34%), Positives = 72/114 (63%), Gaps = 2/114 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+R+K++ R+ I +R+ ++ T +E+D++ ++A+R++ + F ++ IK+ +
Sbjct: 208 EERIKLSMLRKTIGKRMTESFYTAPHALCIDEVDVTDLVAYREEMKNHFVEEKEIKITYL 267
Query: 323 SPFVKAAANALMDQPVVNAVI-EENE-IIYRDYVDISVAVATPKGLVVPVIRNV 478
+KA AL D P NA + EEN+ +I + Y +I +AV TP+GL VPVI++V
Sbjct: 268 PFMIKAVMLALKDYPRFNAQLDEENQMLILKKYYNIGIAVDTPEGLTVPVIKDV 321
>UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=1;
Mycoplasma pulmonis|Rep: DIHYDROLIPOAMIDE
ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE
COMPLEX - Mycoplasma pulmonis
Length = 315
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/134 (33%), Positives = 75/134 (55%), Gaps = 2/134 (1%)
Frame = +2
Query: 104 PQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLD 283
P SKE+A +R K+ R+ IA+ +K++Q+ A ++ +EIDM+ + RK ++
Sbjct: 73 PVSPSKEVAKLEA-RREKVTTIRKAIARAMKNSQDNVAYVSLVHEIDMTKLWDLRKSVVE 131
Query: 284 TFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLV 457
IKL + +KA A A+ D + A +E E++Y D V++ VAV T GL+
Sbjct: 132 KVKDLTGIKLTFLPFILKAIAIAIKDFQIFGAKYDEKTEELVYPDTVNLGVAVDTDHGLM 191
Query: 458 VPVIRNVQNMTYAD 499
VPVI+N Q++ +
Sbjct: 192 VPVIKNAQSLNLVE 205
>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=37; Bacillales|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Bacillus subtilis
Length = 424
Score = 72.9 bits (171), Expect = 5e-12
Identities = 41/136 (30%), Positives = 72/136 (52%)
Frame = +2
Query: 95 KVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK 274
K P++ + A ++ + + R+ IA +K ++ T E+D+++++A+R
Sbjct: 178 KPEPKEETSYPASAAGDKEIPVTGVRKAIASNMKRSKTEIPHAWTMMEVDVTNMVAYRNS 237
Query: 275 HLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGL 454
D+F K L + FVKA A AL + P +N++ ++II + ++IS+AVAT L
Sbjct: 238 IKDSFKKTEGFNLTFFAFFVKAVAQALKEFPQMNSMWAGDKIIQKKDINISIAVATEDSL 297
Query: 455 VVPVIRNVQNMTYADI 502
VPVI+N T I
Sbjct: 298 FVPVIKNADEKTIKGI 313
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/137 (29%), Positives = 73/137 (53%)
Frame = +2
Query: 104 PQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLD 283
P D + EQ ++ R+ IA R++ + T A LT E+++S ++ R + L
Sbjct: 182 PVDSPQPSDSPNHEQGKPLSAMRRTIADRMQQSLQTTAQLTDVREVEVSALVELRNR-LA 240
Query: 284 TFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVP 463
++ K+ F+KA A AL + P +N ++ + II D+V + +AV+ P GL+VP
Sbjct: 241 AKAERIGFKVSFTDLFLKATALALREVPELNVTVQADRIIEHDHVHLGMAVSVPDGLIVP 300
Query: 464 VIRNVQNMTYADIRAHH 514
V+R+ ++ +RA H
Sbjct: 301 VVRDADQLS---LRAIH 314
>UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue
acetyltransferase component e2 of pyruvate dehydrogenase
protein; n=1; Spiroplasma citri|Rep: Putative
dihydrolipoyllysine-residue acetyltransferase component
e2 of pyruvate dehydrogenase protein - Spiroplasma citri
Length = 427
Score = 72.1 bits (169), Expect = 8e-12
Identities = 43/129 (33%), Positives = 72/129 (55%), Gaps = 2/129 (1%)
Frame = +2
Query: 122 EIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH 301
+I T +R M+ R+ IA+++ ++ A T ID++ ++ R + L ++
Sbjct: 191 QINATGAVRREAMSPIRKAIAKQMTLSKTVIAEATLMKNIDVTKLIEIRAQ-LKGQAEQQ 249
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRN 475
+KL M F+KA A AL D P++NA E+ EII++DY +I +A TP GL+VPV++
Sbjct: 250 GVKLTYMPFFMKACAIALKDFPILNAAYDQEQQEIIFKDYYNIGMATDTPTGLMVPVVKG 309
Query: 476 VQNMTYADI 502
V + I
Sbjct: 310 VDQLNIMQI 318
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 70.9 bits (166), Expect = 2e-11
Identities = 41/126 (32%), Positives = 74/126 (58%), Gaps = 2/126 (1%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G E R KM+ R+ IA+ + ++++T +T +E+D+++++A RK+ + IK
Sbjct: 208 GEFPETREKMSGIRKAIAKAMVNSKHTAPHVTLMDEVDVTNLVAHRKQFKQVAADQ-GIK 266
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
L + VKA +AL PV+N I++ +E+I + Y +I +A T KGL+VPV++N
Sbjct: 267 LTYLPYVVKALTSALKKFPVLNTSIDDKTDEVIQKHYFNIGIAADTEKGLLVPVVKNADR 326
Query: 485 MTYADI 502
+ +I
Sbjct: 327 KSVFEI 332
>UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=1; Croceibacter atlanticus HTCC2559|Rep: Lipoamide
acyltransferase component of branched-chain
alpha-ketoacid dehydrogenase complex - Croceibacter
atlanticus HTCC2559
Length = 480
Score = 70.5 bits (165), Expect = 3e-11
Identities = 35/122 (28%), Positives = 71/122 (58%), Gaps = 1/122 (0%)
Frame = +2
Query: 140 TEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGL 319
T + V+M+R R IA + +++T+ +T + E DM+ I+ +R + F + + KL
Sbjct: 246 TGKIVEMDRMRSMIADHMVYSKHTSPHVTAYVEADMTDIVNWRNANKVKFQETYGEKLTF 305
Query: 320 MSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYA 496
FV+A ANA+ + P++N ++ II ++++++ +A A P G L+VPV+++
Sbjct: 306 TPLFVEAVANAITEFPMINVSVDGRNIIVKEHINVGMATALPSGNLIVPVVKDADKKNLQ 365
Query: 497 DI 502
++
Sbjct: 366 EL 367
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/112 (28%), Positives = 67/112 (59%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R++IA + ++ T+A + E+D + I+ R+K+ ++F +K +KL + +A A+
Sbjct: 332 RKKIADHMVMSKRTSAHVHGVFEVDFTKIVKLREKNKNSFQEKTGLKLTYTPFYARAVAH 391
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIR 505
AL P++NA +E I Y+ +++ +AVA GL+VPV++ +++ ++
Sbjct: 392 ALRAWPIINASVEGENIHYKKDINLGIAVALDWGLIVPVVKQADGLSFVGLQ 443
>UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 414
Score = 69.3 bits (162), Expect = 6e-11
Identities = 38/111 (34%), Positives = 65/111 (58%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA++++ + NT E+ M I+ R+ L++ K+ K+ L + +KAA
Sbjct: 197 RKIIAEKMQKSINTAPHFYVTMEVKMREILKLRET-LNSKLKEDEAKISLNTLLMKAAGI 255
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
A+ D P+ N+ +EE +II R+ ++I +AVA +GL+VPVIR V +I
Sbjct: 256 AIKDYPIFNSYVEEGQIILRNEINIGLAVALDEGLIVPVIREVDKKGLKEI 306
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 69.3 bits (162), Expect = 6e-11
Identities = 41/136 (30%), Positives = 74/136 (54%), Gaps = 2/136 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+R+ + R++IA+++ + T +T +E+D++ ++ RK +L + K IKL +
Sbjct: 200 EERIPLRGLRKKIAEKMVKSAYTAPHVTGMDEVDVTKLVEIRK-NLASELAKEQIKLTYL 258
Query: 323 SPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+KA AL P+ NA ++E NEI+ + I +A AT GLVVPVIR+ +
Sbjct: 259 PFIIKAVTRALKQYPMFNASLDEETNEIVLKKRYHIGIATATKAGLVVPVIRDADQKSIR 318
Query: 497 DIRAHHSWASGKSENR 544
++ + S K+ +
Sbjct: 319 ELAIEIAELSEKAHRQ 334
>UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase
component ofpyruvate deshydrogenase complex; n=1;
Mycoplasma agalactiae|Rep: Dihydrolipoamide
acetyltransferase component ofpyruvate deshydrogenase
complex - Mycoplasma agalactiae
Length = 244
Score = 69.3 bits (162), Expect = 6e-11
Identities = 41/123 (33%), Positives = 71/123 (57%), Gaps = 2/123 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+ ++ R+ IA+ LK+ ++A + + D++++ R K D +H++KL +
Sbjct: 13 EKEAPISGIRKAIAKNLKEVLESSAYCSLVLKADVTNLWNLRAKVKDKVFAEHNVKLTFL 72
Query: 323 SPFVKAAANALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
S VKA+A AL + P A + E ++ Y ++I +AV TP GL VPVIR V+N++
Sbjct: 73 SWIVKASAIALSEYPSFAARWDGVEGKVYYPGTLNIGIAVDTPFGLFVPVIRGVENLSII 132
Query: 497 DIR 505
DI+
Sbjct: 133 DIQ 135
>UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04170 protein - Schistosoma
japonicum (Blood fluke)
Length = 233
Score = 69.3 bits (162), Expect = 6e-11
Identities = 35/64 (54%), Positives = 42/64 (65%)
Frame = +2
Query: 65 HAQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEID 244
H + E+ P + TR EQRVKM+R R RIAQRLKDAQ T AML+TFNEID
Sbjct: 168 HPPSTESVPCYTSPPSVPTSLDSTRAEQRVKMSRMRLRIAQRLKDAQTTCAMLSTFNEID 227
Query: 245 MSHI 256
MS++
Sbjct: 228 MSNL 231
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 68.9 bits (161), Expect = 8e-11
Identities = 44/146 (30%), Positives = 78/146 (53%), Gaps = 2/146 (1%)
Frame = +2
Query: 71 QAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMS 250
Q ++T V S E G+ E+R+ + R+ IA+++ + T +T +EI+M
Sbjct: 159 QKVKTVPSGVANVQESIERTGSSAEKRIPLKGIRKAIAEKMIKSVATIPHVTHVDEIEMD 218
Query: 251 HIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDI 424
+ R++ L ++++ IKL + F+KA +AL + NA I+E NEI+ + I
Sbjct: 219 ALKELREQ-LKHYSEQKGIKLTFLPFFIKAIVSALKEFEYFNASIDEETNEIVLKKDYHI 277
Query: 425 SVAVATPKGLVVPVIRNVQNMTYADI 502
+A T KGL+VPVI+N + ++
Sbjct: 278 GIATDTEKGLIVPVIQNADQKSLLEL 303
>UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=5;
Legionellales|Rep: Pyruvate dehydrogenase E2 component -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 550
Score = 68.1 bits (159), Expect = 1e-10
Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 2/110 (1%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 394
+T F+E D++ + AFRK ++ K KL L++ AL P NA ++ +
Sbjct: 348 VTQFDEADITDLEAFRKSESES-AKNQDYKLTLLAFVCSVVCKALHAYPQFNASLDTSGE 406
Query: 395 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSENR 544
+IY+ Y +I +AV TP GLVVPVI+NV ++ DI S S K+ +
Sbjct: 407 NLIYKKYYNIGIAVDTPNGLVVPVIKNVDKLSVIDIAKEMSRLSTKAREK 456
>UniRef50_Q4E6V7 Cluster: Putative uncharacterized protein; n=1;
Wolbachia endosymbiont of Drosophila simulans|Rep:
Putative uncharacterized protein - Wolbachia
endosymbiont of Drosophila simulans
Length = 173
Score = 68.1 bits (159), Expect = 1e-10
Identities = 40/83 (48%), Positives = 51/83 (61%)
Frame = -2
Query: 366 GWSIRALAAAFTKGDIRPSLMLCFLVKVSRCFLRNAMMWDMSISLNVVNMAFVF*ASFKR 187
G S A AAF K DI+PS + F K S F+ +M + MSISLNVV++A VF +FKR
Sbjct: 13 GISFSACTAAFIKNDIKPSFIPYFFSKASLYFVLRSMTFFMSISLNVVSIAAVFCDAFKR 72
Query: 186 *AMRCLPLFILTRCSVRVPAISL 118
A+ CL L I TR S+ P +L
Sbjct: 73 AAITCLILLIFTRSSLCSPFTTL 95
>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase; n=4;
Geobacter|Rep: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase -
Geobacter sulfurreducens
Length = 392
Score = 67.7 bits (158), Expect = 2e-10
Identities = 38/135 (28%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+R+ + R+ IA+ + +Q A +T E D++ + R++ ++ L +
Sbjct: 162 ERIPLRGVRRSIARNVMTSQRNTAFVTGMEEADITELWHLREREQQA-VEQRGTHLTFLP 220
Query: 326 PFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
F+KA +AL + P +NA I++ EII + + +AV TP GL+VPVIRNV + +
Sbjct: 221 FFIKAVQHALREHPYLNAAIDDVAGEIILKKHYHFGIAVETPDGLMVPVIRNVDAKSIIE 280
Query: 500 IRAHHSWASGKSENR 544
+ + K+ R
Sbjct: 281 LASELQELGRKARER 295
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 66.9 bits (156), Expect = 3e-10
Identities = 33/121 (27%), Positives = 74/121 (61%), Gaps = 2/121 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
++V + R+ A+ +KD+ +T A++T F D++ M + L + +++ ++
Sbjct: 237 RKVPVRGVRKVTAKAVKDSLDTKALVTAFLTCDVTPTMELVNR-LRADRRFKGLRVSPLT 295
Query: 326 PFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
+ KA A+ P++NA ++ ++I++RD++++ +A ATP+GL+VPV+R+ Q+M +
Sbjct: 296 VWCKAVCLAMGRTPIINAAWDDAADQIVFRDHINLGIAAATPRGLMVPVVRDAQDMAMLE 355
Query: 500 I 502
+
Sbjct: 356 L 356
>UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase, E2 component
- Alcanivorax borkumensis (strain SK2 / ATCC 700651 /
DSM 11573)
Length = 564
Score = 66.9 bits (156), Expect = 3e-10
Identities = 42/135 (31%), Positives = 73/135 (54%), Gaps = 2/135 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+RV++N+ R+ AQ L + T +T + D++ + AFRK + ++ +KL +++
Sbjct: 337 ERVELNKLRKVSAQNLTRSWLTIPHVTQHDNADITDLEAFRKSQ-NKRLEREGVKLTMLA 395
Query: 326 PFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
V A A AL + P N+ +E + +I + Y++I +AV TP GLVVPVI++
Sbjct: 396 FLVAACARALKEYPRFNSSLENSGEALIEKRYINIGIAVDTPNGLVVPVIKDADKKGLKA 455
Query: 500 IRAHHSWASGKSENR 544
I + K+ NR
Sbjct: 456 IAQEMDELAEKARNR 470
>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
component; n=2; Alteromonadales|Rep: Apha keto acid
dehydrogenase complex, E2 component - Idiomarina baltica
OS145
Length = 515
Score = 66.9 bits (156), Expect = 3e-10
Identities = 39/131 (29%), Positives = 80/131 (61%), Gaps = 2/131 (1%)
Frame = +2
Query: 116 SKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTK 295
+++ GTRTE + + +A+++ ++ +T T +E D+++++A R+K + + K
Sbjct: 277 AQQSGGTRTEA---IRGVKAAMAKQMMNSVSTIPHFTYSDEFDLTNLIALREKLKEQY-K 332
Query: 296 KHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVI 469
+ ++L +M F+KA + AL + P++NA + ++ E+ Y D +I +AV T GL+VP +
Sbjct: 333 EQGVRLTVMPFFIKALSLALKEFPIMNAQVNDDCTEVTYFDDHNIGMAVDTKIGLLVPNV 392
Query: 470 RNVQNMTYADI 502
+ VQN + D+
Sbjct: 393 KQVQNKSIIDV 403
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 66.5 bits (155), Expect = 4e-10
Identities = 48/157 (30%), Positives = 76/157 (48%), Gaps = 2/157 (1%)
Frame = +2
Query: 80 ETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIM 259
E AT K P+ + + + ++ +M R++ A+RL A T +T + D++ +
Sbjct: 364 EAATAKAAPKVVLPDFSKWGSIEKEQMRSIRRKTAERLTQAWTTIPHVTQHDRADITELE 423
Query: 260 AFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIE--ENEIIYRDYVDISVA 433
R+K + KL + + +K A A+ P NA I+ EIIY+ YV I VA
Sbjct: 424 KLREKFAKQ-AEAAGGKLTVTAIALKVIAAAMKKFPKFNASIDIDREEIIYKKYVHIGVA 482
Query: 434 VATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSENR 544
V T GL+VPV+RNV I A + S ++ R
Sbjct: 483 VDTEAGLLVPVLRNVDQKNVYQIAAEMNELSKRARER 519
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 66.1 bits (154), Expect = 5e-10
Identities = 40/113 (35%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
++R+ + R+ IA+R+ ++ T +TT E+DM+ +MAFR + + +K IKL M
Sbjct: 219 DERIPLRGIRKVIAERMVKSKYTAPHVTTVEEVDMTELMAFRAQAKELAARK-GIKLSFM 277
Query: 323 SPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRN 475
+KA AL + P +NA I E EI+ I A+ T GL+VPVI++
Sbjct: 278 PFIIKAVVAALREFPYLNASIDDEAQEIVLHKRYHIGFALDTDAGLLVPVIKD 330
>UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2; unclassified
Gammaproteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - marine gamma
proteobacterium HTCC2143
Length = 568
Score = 66.1 bits (154), Expect = 5e-10
Identities = 45/151 (29%), Positives = 81/151 (53%), Gaps = 2/151 (1%)
Frame = +2
Query: 98 VPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH 277
VP D+SK + E K++R AQ + + +T F++ ++S + FR+
Sbjct: 329 VPDIDFSK-FGEVKLESLSKIHRAT---AQNMHRSWLNVPHVTQFDDANISDLEEFRQS- 383
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKG 451
L ++ +K+ + +KA A AL + P NA + + +++Y+ YV+I +AV TP G
Sbjct: 384 LKAEAERRGVKITPLPFLLKACAAALRENPKFNASLHTSGHQLVYKQYVNIGIAVDTPLG 443
Query: 452 LVVPVIRNVQNMTYADIRAHHSWASGKSENR 544
LVVPVIR+V + ++ A + K+++R
Sbjct: 444 LVVPVIRDVDKKSIWELAAETVEMAQKAKDR 474
>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Mycobacterium leprae|Rep: Dihydrolipoamide
succinyltransferase - Mycobacterium leprae
Length = 530
Score = 65.7 bits (153), Expect = 7e-10
Identities = 38/118 (32%), Positives = 63/118 (53%), Gaps = 2/118 (1%)
Frame = +2
Query: 155 KMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFV 334
K++R RQ A++ +++ A LT +E+DM+ I+ R K F ++ + L +
Sbjct: 297 KVSRIRQITAKKTRESLQATAQLTQTHEVDMAKIVGLRAKAKAAFAEREGVNLTFLPFIA 356
Query: 335 KAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
KAA +AL P +NA E+ EI Y D + A+ T KGL+ PVI +++ A +
Sbjct: 357 KAAIDALKIHPNINASYNEDTKEITYYDAEHLGFAIDTDKGLLSPVIHYAGDLSLAGL 414
>UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=8; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Bacteroides thetaiotaomicron
Length = 456
Score = 64.9 bits (151), Expect = 1e-09
Identities = 31/112 (27%), Positives = 66/112 (58%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 KMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFV 334
+M+R R+ IA + ++ + +T E+D++ ++ +R+K+ D F ++ +KL M
Sbjct: 231 EMDRVRRIIADHMVMSKKVSPHVTNVVEVDVTKLVRWREKNKDAFFRREGVKLTYMPVIT 290
Query: 335 KAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNM 487
+A A AL P VN ++ I+++ +++I +AV+ G L+VPV+ + ++
Sbjct: 291 EAVAKALAAYPQVNVSVDGYNILFKKHINIGIAVSLNDGNLIVPVVHDADHL 342
>UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacteria
(class)|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 487
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/144 (30%), Positives = 70/144 (48%), Gaps = 3/144 (2%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
Q K++R R +A+R+ ++ +A LTT E D++ I R + F + IKL +
Sbjct: 251 QTEKLSRLRALVARRMVESLQISAQLTTVVEADVTRIARLRDRAKSGFQAREGIKLSFLP 310
Query: 326 PFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
F A AL + P +N+ I E + Y ++ +AV + +GLVVPVI N ++
Sbjct: 311 FFALATCAALREFPQLNSSIDVEAGTVTYHGEENLGIAVDSERGLVVPVIHNAGDLNLIG 370
Query: 500 I-RAHHSWASGKSENR*AHDRKNG 568
+ R AS NR + D G
Sbjct: 371 LARKIDDLASRTRANRISPDELGG 394
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 64.9 bits (151), Expect = 1e-09
Identities = 37/124 (29%), Positives = 66/124 (53%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
GT + + + +++ R+ IA+RL ++ T EI M IM RK+ +K
Sbjct: 319 GTESYEEINVSQMRKTIAKRLASSKFTAPHFYVTMEIRMDAIMKARKQ----INAVSPVK 374
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMT 490
+ +KA+A A+ P +NA E++I Y +++ + +AVA GL VPV+R N+T
Sbjct: 375 VSFNDIIIKASALAIRKHPKINAYWLEDKIRYNNHIHVGMAVAVKDGLFVPVVRFADNLT 434
Query: 491 YADI 502
++ +
Sbjct: 435 FSQV 438
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Frame = +2
Query: 86 ATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAF 265
A++ +P Y AG E+RV M R++IA+ ++ +++ T +E + ++A
Sbjct: 295 ASMTIPKPAYQGP-AGA-AEERVPMIGIRKKIAENMQRSKHVIPHFTIMDEAKVDAMVAL 352
Query: 266 RKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVA 439
R+ L +K+ K+ + +KA + + P+ NA I++ EI+Y+ Y ++ A
Sbjct: 353 RES-LKEHAEKNGTKITYLPIIMKALIATIREFPMFNASIDDAAGEIVYKKYFNLGFAAD 411
Query: 440 TPKGLVVPVIRNVQNMTYADI 502
TP GLVVPVI+N + +I
Sbjct: 412 TPNGLVVPVIKNADQKSILEI 432
>UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2
component, putative; n=2; Streptococcus|Rep:
Dihydrolipoamide acetyl transferase, E2 component,
putative - Streptococcus sanguinis (strain SK36)
Length = 419
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/112 (32%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKK-HSIKLGLMSPFVKAAA 346
R+ IA+R+ ++ +A +T ++D+S ++AFR+ T + ++ + + KA A
Sbjct: 199 RKTIAERMMNSLQASAQVTLHRKVDISRLIAFRQDMKGKVTSPLENGEISITTLLTKAVA 258
Query: 347 NALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
AL D P +NA + + + I +A A GLVVPVIR+V +T AD+
Sbjct: 259 KALKDHPQLNAWYFNGQYQEVEDIHIGIATALSDGLVVPVIRHVDKLTLADL 310
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 64.1 bits (149), Expect = 2e-09
Identities = 37/121 (30%), Positives = 66/121 (54%), Gaps = 2/121 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+RV + R+ IAQ + + T +T F E D + ++ R++ + ++ +KL ++
Sbjct: 208 RRVPLTGIRKAIAQAMVRSTRTIPQVTHFGEADATRLVQHRRR-IQPLAEQQGVKLTYLA 266
Query: 326 PFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
VKA A L P++NA ++E EI+ +++ I AV T +GL+VPVIR+ +
Sbjct: 267 YVVKALAAVLKKYPMLNASLDEEREEIVIHEFIHIGFAVDTDRGLLVPVIRDADQKSLFQ 326
Query: 500 I 502
I
Sbjct: 327 I 327
>UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
AceF protein - Wigglesworthia glossinidia brevipalpis
Length = 496
Score = 63.7 bits (148), Expect = 3e-09
Identities = 35/110 (31%), Positives = 65/110 (59%), Gaps = 2/110 (1%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EEN 394
+T F ++D+S + +FRK +T K+ +K+ ++S +K+ AL + P+ N+ + ++N
Sbjct: 295 VTQFEQVDISELESFRKNQNNTL--KYKVKITILSFIIKSVFFALKEYPLFNSSLSKDKN 352
Query: 395 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSENR 544
++I + Y +I +AV+T GLVVPVI +V +I S K+ N+
Sbjct: 353 KLILKKYFNIGIAVSTDYGLVVPVIFDVDKKGIIEISHELFNISNKARNK 402
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 63.7 bits (148), Expect = 3e-09
Identities = 36/132 (27%), Positives = 72/132 (54%)
Frame = +2
Query: 107 QDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDT 286
+D +K ++ + Q + + R+ IA R++++ +A LT + D++ + +K+ T
Sbjct: 160 KDQAKPVSEQKA-QEIPVTGMRKVIAARMQESLANSAQLTITMKADITKLATLQKQLSPT 218
Query: 287 FTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPV 466
+++ KL + +AA AL PV+N+ + II +V + +AVA GLVVPV
Sbjct: 219 AEERYGTKLTITHFVSRAAVLALQAHPVLNSFYQNERIITHPHVHLGMAVALENGLVVPV 278
Query: 467 IRNVQNMTYADI 502
IR+ + ++ ++
Sbjct: 279 IRHAEKLSLIEL 290
>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
Pyruvate dehydrogenase E2 component dihydrolipoamide
acetyltransferase - Mycoplasma mobile
Length = 453
Score = 63.3 bits (147), Expect = 4e-09
Identities = 36/121 (29%), Positives = 68/121 (56%), Gaps = 2/121 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+R K+ R+ IA+ +K++ + A NEI++ +++ R+K D+ +K+ +
Sbjct: 224 KREKVTPIRKAIAKAMKNSWSNVAYTNLVNEINVGSLVSLREKIKDSVQDLTGVKVTFLP 283
Query: 326 PFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
+KA AL + PV+ A +E +E++Y ++I +AV T GL+VPVI+N + +
Sbjct: 284 FIIKAITLALKEFPVLMAKYDEQASELVYSGTLNIGIAVDTEAGLMVPVIKNADKLNIIE 343
Query: 500 I 502
I
Sbjct: 344 I 344
>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
catalytic domain - Anaeromyxobacter sp. Fw109-5
Length = 454
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 2/127 (1%)
Frame = +2
Query: 128 AGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSI 307
+G ++RV + R+RIA+ + ++ T A T + D++ + A K+ + K+ +
Sbjct: 218 SGGAADERVPLRGVRKRIAENMARSKRTAAHFTFVEQCDVTEL-ARVKERMAVAAKEEGV 276
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQ 481
KL + VKA AL P +NA + E E++ D+ +A AT GLVVPV+R
Sbjct: 277 KLTFLPFVVKAVVAALRKHPKLNATMDDERGELVLHRRYDVGIASATDAGLVVPVVRGAD 336
Query: 482 NMTYADI 502
+ ++
Sbjct: 337 RRSLVEL 343
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 62.9 bits (146), Expect = 5e-09
Identities = 40/137 (29%), Positives = 72/137 (52%), Gaps = 2/137 (1%)
Frame = +2
Query: 140 TEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGL 319
T +R M+ R+ + + A T M+T F++ D++ + RK+ +K KL +
Sbjct: 386 TVRREDMSGIRKATVRSMTTAWTTIPMVTHFDKADVTAMEETRKR-FGARVEKEGGKLTM 444
Query: 320 MSPFVKAAANALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 493
+K ANAL P NA ++ ++IY+++V+I VAV TP GL+VPV+++
Sbjct: 445 THILMKVVANALRKFPKFNASLDLGAEQVIYKEFVNIGVAVDTPVGLLVPVVKDADRKGI 504
Query: 494 ADIRAHHSWASGKSENR 544
++ S +G++ R
Sbjct: 505 TELVLDLSELAGRARER 521
>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
alpha-keto acid dehydrogenase E2 - Symbiobacterium
thermophilum
Length = 459
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/111 (28%), Positives = 63/111 (56%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+RIA ++ A++ T ++D+++++ R++ F + L + F+KA
Sbjct: 237 RRRIAAKMVQAKHEAPHAWTMMQVDVTNLVKLREQAGPEFRARTGRPLSYVPFFIKAVVE 296
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+L + P++N+ +EI+ R ++ISVAVAT L VPVI++ ++ A +
Sbjct: 297 SLREYPILNSQWNGDEIVIRQDINISVAVATEDALAVPVIKHADRLSIAGL 347
>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 555
Score = 62.5 bits (145), Expect = 7e-09
Identities = 42/131 (32%), Positives = 74/131 (56%), Gaps = 2/131 (1%)
Frame = +2
Query: 116 SKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTK 295
SK GTR E +++ + +A+++K + +T T EI M ++A R + D F++
Sbjct: 317 SKVQGGTRVE---RISGIKAAMARQMKHSVSTIPHFTVSEEIQMDALIALRSQLKDDFSE 373
Query: 296 KHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVI 469
+ +KL M F+KA + AL PV+N+ + ++ ++ Y + +I AV GL+VP I
Sbjct: 374 Q-GVKLSFMPFFIKALSLALKAYPVINSQVNDDCTQLTYFNEHNIGFAVDGKLGLMVPNI 432
Query: 470 RNVQNMTYADI 502
+ VQ+M+ DI
Sbjct: 433 KGVQDMSIFDI 443
>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
Drosophila melanogaster (Fruit fly)
Length = 462
Score = 62.5 bits (145), Expect = 7e-09
Identities = 36/93 (38%), Positives = 58/93 (62%), Gaps = 3/93 (3%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSI-KLGLMSPFVKAAANALMDQPVVNAVIE--ENEII 403
+EIDM+ +M FR + L K++ + KL M +KAA+ AL P+VN+ ++ ++
Sbjct: 261 DEIDMTQLMQFRNQ-LQLVAKENGVPKLTFMPFCIKAASIALSKYPIVNSSLDLASESLV 319
Query: 404 YRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
++ +ISVA+ TP+GLVVP I+N Q T +I
Sbjct: 320 FKGAHNISVAIDTPQGLVVPNIKNCQTKTIIEI 352
>UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component; n=1; Mycoplasma
penetrans|Rep: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component - Mycoplasma
penetrans
Length = 478
Score = 62.1 bits (144), Expect = 9e-09
Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
++M R+ IA +K + + A EID++ + R K D + ++KL L+
Sbjct: 252 LEMTSMRKAIANAMKRSWSNAAYTNLSVEIDVTDVWEQRNKIKDYILETENVKLNLLPFI 311
Query: 332 VKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+KA A L P+ NA+ ++ +I R+ V+I +AV T GL+VP I+N ++ +I
Sbjct: 312 IKAIAKTLKQFPIFNAINDDANGTLILRNEVNIGIAVDTKDGLIVPNIKNADKLSIIEI 370
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 62.1 bits (144), Expect = 9e-09
Identities = 34/120 (28%), Positives = 64/120 (53%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+R+ + R+ IA + + + ++ F ++D + M F K+ L + +K+ +
Sbjct: 226 EERILVKGVRKAIANAMVTSAFSAPHVSVFVDVDATRTMEFVKR-LKSAPDFVGVKVSPL 284
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
KA A+ P VN+ + EII R YV++ +A ATP+GL+VP ++ Q M+ ++
Sbjct: 285 LIMAKAIVWAVRRNPTVNSTWTDEEIIVRHYVNLGIAAATPRGLIVPNVKEAQGMSLLEL 344
>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
component - Deinococcus radiodurans
Length = 525
Score = 61.7 bits (143), Expect = 1e-08
Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E RV + R+ IA +++ + T +E++++ ++ FR++ D K +KL +
Sbjct: 293 ETRVPLRGMRRAIANQMQASHLYTVRTLTVDEVNLTKLVEFRQRVKDE-AKAADVKLSYL 351
Query: 323 SPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
KA AL P +N +E EI+ + Y ++ +AVAT GL VPVIR+V +
Sbjct: 352 PFIFKAITVALKKYPSLNTSFDEATQEIVQKSYYNLGMAVATEAGLTVPVIRDVDRKSIF 411
Query: 497 DI 502
D+
Sbjct: 412 DL 413
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 61.7 bits (143), Expect = 1e-08
Identities = 34/122 (27%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+R+ + R+ I+ L + A +T F++ D++ + R++ +K +K+ +
Sbjct: 198 EERIPLRGIRRTISDNLMRSLQHTAQVTVFDDADVTKLSELREQV--NGARKDGVKVSYL 255
Query: 323 SPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+ VKA + AL + PV+NA I E+ EI+ + Y +I +A+ TP+GL+V +++ +
Sbjct: 256 AFTVKAVSAALRNHPVLNASIDDEKGEIVLKKYYNIGLAIDTPRGLMVAPVKDADRKSIV 315
Query: 497 DI 502
I
Sbjct: 316 QI 317
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 36/133 (27%), Positives = 67/133 (50%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
++ + +N R+ IA+ + ++ E+D + ++ +R D+F K+ L
Sbjct: 186 DKEIPINGVRKAIAKHMSVSKQEIPHAWMMVEVDATGLVRYRNTVKDSFKKEEGYSLTYF 245
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ F+KA A AL + P +N+ ++II ++IS+A+A L VPVI+N + I
Sbjct: 246 AFFIKAVAQALKEFPQLNSTWAGDKIIEHANINISIAIAAGDLLYVPVIKNADEKSIKGI 305
Query: 503 RAHHSWASGKSEN 541
S +GK+ N
Sbjct: 306 AREISELAGKARN 318
>UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase
complex E2 component; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to 2-oxoglutarate
dehydrogenase complex E2 component - Candidatus Kuenenia
stuttgartiensis
Length = 416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 35/120 (29%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 119 KEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKK 298
K + E + ++ R+ A+R+ ++ T A++TT E+DM+ + +R+ + + K+
Sbjct: 165 KIVKEAERETLIPLHPKRKITAERMALSRQTAALVTTVFEVDMTPVTKYRELNREAM-KR 223
Query: 299 HSIKLGLMSPFVK-AAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRN 475
I L + PF+ A AL + +N+ +N I+ ++Y+++ +AVA GLVVPVI++
Sbjct: 224 EGIHLTYL-PFIAFAVVQALKEHVALNSSWTDNGILQKNYINLGIAVALEDGLVVPVIKD 282
>UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransferase;
n=1; Tetrahymena thermophila SB210|Rep: 2-oxo acid
dehydrogenases acyltransferase - Tetrahymena thermophila
SB210
Length = 462
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/145 (29%), Positives = 78/145 (53%), Gaps = 3/145 (2%)
Frame = +2
Query: 80 ETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIM 259
ET K S + + VKM+ ++ + + + +A NT L +E D++++
Sbjct: 204 ETTKPKAASTASSSGVLNETVKTTVKMSDFQKGMQKSMTEA-NTIPHLYLKDEYDLTNLT 262
Query: 260 AFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYV---DISV 430
R++ K + + M+ F+KA + AL + P++N++ + N+ V +IS+
Sbjct: 263 VLREQ----IKKSQNQSITFMTFFIKAFSLALKEYPILNSLYDVNKPFEYTLVQNHNISL 318
Query: 431 AVATPKGLVVPVIRNVQNMTYADIR 505
AV +PKGLVVP I+NVQN++ DI+
Sbjct: 319 AVDSPKGLVVPNIKNVQNLSILDIQ 343
>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 435
Score = 60.9 bits (141), Expect = 2e-08
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 3/158 (1%)
Frame = +2
Query: 104 PQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLD 283
P ++ G R ++ + R+RIA+ + + T +ID++ ++ RK+
Sbjct: 190 PAPVARPSVGPREDEYIPFRGMRRRIAEGMVKSYTEAVHYTYVEQIDVTKLVTLRKQ-AK 248
Query: 284 TFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLV 457
+ + L + +KA +AL P+VNA ++E I+ + I VA AT +GL+
Sbjct: 249 KAAAEQGVSLSYLPFIIKAVCHALKRFPIVNAELDEAQKRIVLKKRYSIGVAAATDQGLM 308
Query: 458 VPVIRNVQNMTYADI-RAHHSWASGKSENR*AHDRKNG 568
VPVI + ++ D+ R G R A D G
Sbjct: 309 VPVIHDADMLSLLDLAREVKRLGEGAKTGRLARDELTG 346
>UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein - Yarrowia lipolytica
(Candida lipolytica)
Length = 466
Score = 60.9 bits (141), Expect = 2e-08
Identities = 31/71 (43%), Positives = 47/71 (66%), Gaps = 4/71 (5%)
Frame = +2
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVIE----ENEIIYRDYVDISVAVATPKGLVVPVIRN 475
K+ M F+KA + AL D P+VNA ++ + ++ RDY +IS+A+ TP GL+VP I+N
Sbjct: 286 KISYMPFFIKALSLALKDYPMVNAKVDLSGDKPAVLMRDYHNISIAMDTPNGLLVPTIKN 345
Query: 476 VQNMTYADIRA 508
VQ+ T +I A
Sbjct: 346 VQDKTIVEIAA 356
>UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Tribolium
castaneum
Length = 429
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/92 (36%), Positives = 55/92 (59%), Gaps = 2/92 (2%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIY 406
+EI ++ + R+ L + +KL M F+KAA+NAL PV+NA ++EN + Y
Sbjct: 228 DEIAVTQLSQLRQT-LKKLPETQDLKLSFMPFFIKAASNALQRFPVLNASLDENCENVTY 286
Query: 407 RDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ +I VA+ T GL VPVI+NV+ ++ +I
Sbjct: 287 KSEHNIGVAMDTKVGLAVPVIKNVETLSIIEI 318
>UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Plesiocystis pacifica SIR-1|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Plesiocystis pacifica
SIR-1
Length = 436
Score = 60.5 bits (140), Expect = 3e-08
Identities = 41/134 (30%), Positives = 65/134 (48%)
Frame = +2
Query: 134 TRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKL 313
+R + V+++ R+ IA+ + A+ ++DM AFR + + K+
Sbjct: 204 SRPDDSVRLSMMRKAIARNMTKAKQETPHYYLTMDVDMEKAFAFRADFNEAVPE--GTKI 261
Query: 314 GLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 493
VKA A +L D P VNA + ++ I R V++ +AVA GLVVPV+R +
Sbjct: 262 SFNDLIVKAVARSLRDFPSVNASFDGDKAIIRGDVNVGIAVAVEDGLVVPVVRYADQKSL 321
Query: 494 ADIRAHHSWASGKS 535
I + S A GKS
Sbjct: 322 EAI-SRESKALGKS 334
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/136 (29%), Positives = 67/136 (49%)
Frame = +2
Query: 68 AQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
A+ E V+ P A R E+ + M+ R+ I+ R+ ++ + +T ID+
Sbjct: 198 AKQKEKTIVQEPENQAVTSKAAGRGEKVINMSSMRKVISARMSESVKISPTVTYNINIDI 257
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDIS 427
S + + DTF KL +K + AL P+VN I + I +DYV++
Sbjct: 258 SELKRLKNNLKDTF------KLTYTDFLIKIVSAALKQFPLVNCSISGGKFILKDYVNMG 311
Query: 428 VAVATPKGLVVPVIRN 475
VAVA +GL+VPV+++
Sbjct: 312 VAVALDEGLIVPVVKD 327
>UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase; n=3;
Staphylococcus|Rep: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 425
Score = 60.1 bits (139), Expect = 4e-08
Identities = 38/128 (29%), Positives = 67/128 (52%), Gaps = 2/128 (1%)
Frame = +2
Query: 158 MNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKK--HSIKLGLMSPF 331
+N RQRIAQ ++ + N+ A LT ++D ++ F K L T K+ +KL + +
Sbjct: 202 LNPMRQRIAQNMRQSLNSTAQLTLHRKVDADRLLDF-KDRLATELKQADQDVKLTVTTLL 260
Query: 332 VKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAH 511
KA AL + +NA E+ E+ + V + +A + +GL+VPVI + + + AH
Sbjct: 261 AKAVVLALKEYGAMNARYEQGELTEYEDVHLGIATSLDEGLMVPVINHADTKSIGTL-AH 319
Query: 512 HSWASGKS 535
+S ++
Sbjct: 320 EIKSSAEA 327
>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 432
Score = 60.1 bits (139), Expect = 4e-08
Identities = 34/123 (27%), Positives = 60/123 (48%)
Frame = +2
Query: 134 TRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKL 313
T ++ V + R+ IA+++ + N E D+++++ R D F ++ + L
Sbjct: 199 TSPDKIVSADPVRKAIAKKMVQSVNEIPHAWLMVEADVTNLVQLRNSLKDEFKQQEGLSL 258
Query: 314 GLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 493
F KA AL P +N ++ IIY V++S+AV T + L VPVI+ N +
Sbjct: 259 SFFPFFAKAVIQALKKNPKINTSWDDGSIIYHKDVNLSIAVTTDEHLYVPVIQQADNYSI 318
Query: 494 ADI 502
A +
Sbjct: 319 AGL 321
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 60.1 bits (139), Expect = 4e-08
Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 2/138 (1%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R E R RQ I + ++ T +T +E+D++ ++ R L + I+L
Sbjct: 305 RPESRKPYKGIRQTIGAAMTSSKYTAPHVTHQDEVDVTALVDARST-LRREAEAQDIRLT 363
Query: 317 LMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMT 490
M +KA A AL + P VN ++E EI+ + Y +I VA AT GL+VPV+ NV
Sbjct: 364 YMPFVMKACAAALQENPQVNVSLDEANEEIVEKQYYNIGVATATDDGLLVPVVENVDAKG 423
Query: 491 YADIRAHHSWASGKSENR 544
++ + + + K+ R
Sbjct: 424 LLEVASETNEKTQKARER 441
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4;
Magnoliophyta|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 637
Score = 60.1 bits (139), Expect = 4e-08
Identities = 37/113 (32%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+RL +++ L +++ + ++AFRK+ + H +K+ + +KA A
Sbjct: 416 RKIIAKRLLESKQKIPHLYLQSDVVLDPLLAFRKE----LQENHGVKVSVNDIVIKAVAV 471
Query: 350 ALMDQPVVNAV--IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
AL + NA E+ +I+ D VDIS+AVAT KGL+ P+I+N + + I
Sbjct: 472 ALRNVRQANAFWDAEKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSISAI 524
>UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=2; Mycoplasma|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
pneumoniae
Length = 402
Score = 60.1 bits (139), Expect = 4e-08
Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRL-KDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGL 319
E+ + + R+ IA+ + K +N A + TF ++ + + +R+ K+++K+
Sbjct: 172 EETIAITTMRKAIAEAMVKSHENIPATILTFY-VNATKLKQYRESVNGLALSKYNMKISF 230
Query: 320 MSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 493
+ FVKA NAL PV N E N I+ V++ +AV TP GL+VP I+ Q +
Sbjct: 231 FAFFVKAIVNALKKFPVFNGRYDKERNLIVLNKDVNVGIAVDTPDGLIVPNIKQAQTKSV 290
Query: 494 ADI 502
DI
Sbjct: 291 VDI 293
>UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=11; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Psychroflexus torquis
ATCC 700755
Length = 572
Score = 59.7 bits (138), Expect = 5e-08
Identities = 39/139 (28%), Positives = 73/139 (52%)
Frame = +2
Query: 128 AGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSI 307
AG + + VK ++ R+ IA+RL +++N+ E+DM + MA R H++ +
Sbjct: 344 AGEESFEDVKNSQMRKTIAKRLLESKNSAPHYYLNIEVDMENAMASRS-HINEMP---DV 399
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
K+ +KA+A AL P VN+ + +++ + VAVA +GL+VPV+
Sbjct: 400 KVSFNDLVIKASAMALRKHPQVNSSWDGEVTKIANHIHVGVAVAVDEGLLVPVLEFADQQ 459
Query: 488 TYADIRAHHSWASGKSENR 544
+ I ++ +GK++N+
Sbjct: 460 SLTQIGSNVKNLAGKAKNK 478
>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=1; Gramella forsetii KT0803|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Gramella forsetii
(strain KT0803)
Length = 507
Score = 59.3 bits (137), Expect = 6e-08
Identities = 40/126 (31%), Positives = 65/126 (51%), Gaps = 2/126 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ A+ A +T + F+E D+S I ++ ++ +K L + + K +A+
Sbjct: 288 RKATAKNTSAAWSTIPHVFQFDEADISDI----EERMEKLQEKADGNLTITAILAKISAS 343
Query: 350 ALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWA 523
AL P NA I E E+I + YV+I +AV T KGL+VPV+RN T +I +
Sbjct: 344 ALRQFPKFNASIDMENEEMILKKYVNIGIAVDTEKGLLVPVVRNADQKTIIEISTEITEL 403
Query: 524 SGKSEN 541
+ K+ N
Sbjct: 404 AEKARN 409
>UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 484
Score = 59.3 bits (137), Expect = 6e-08
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +2
Query: 125 IAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK-HLDTFTKKH 301
IA + +++ R I RL ++ T ++I ++ ++ R+ + D K +
Sbjct: 244 IAASNPYTDTEISNMRNIIGSRLLESTQTIPSYIVSSDISVTKLLRLRQSLNNDPANKNN 303
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRN 475
KL + VKA + A+ P VN E E + R + VD+SVAVATP GL+ P+++N
Sbjct: 304 DYKLSINDILVKAISLAVKRVPEVNTCWLEKENVIRQFENVDVSVAVATPTGLITPIVKN 363
Query: 476 VQN 484
V +
Sbjct: 364 VNS 366
>UniRef50_P11182 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial precursor (EC 2.3.1.168)
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase); n=29; Eumetazoa|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial
precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) - Homo sapiens (Human)
Length = 482
Score = 59.3 bits (137), Expect = 6e-08
Identities = 33/92 (35%), Positives = 56/92 (60%), Gaps = 2/92 (2%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIY 406
+EID++ ++ R++ L IKL M F+KAA+ L+ P++NA ++EN I Y
Sbjct: 280 DEIDLTELVKLREE-LKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 407 RDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ +I +A+ T +GL+VP ++NVQ + DI
Sbjct: 339 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDI 370
>UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 483
Score = 58.8 bits (136), Expect = 8e-08
Identities = 44/141 (31%), Positives = 65/141 (46%)
Frame = +2
Query: 80 ETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIM 259
E A P + + A + + ++ R+ IA RL +++N N ++M I+
Sbjct: 234 EAAAKATTPAASAADAAAPGDYEDLPLSNMRKIIASRLAESKNMNPHYYVTVSVNMEKII 293
Query: 260 AFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVA 439
R L+ KL + +KA AL P VNA + I VDIS+AVA
Sbjct: 294 RLRAA-LNAMADGR-YKLSVNDLVIKATTAALRQVPEVNAAWMGDFIRQYKNVDISMAVA 351
Query: 440 TPKGLVVPVIRNVQNMTYADI 502
TP GL+ PVIRN + A+I
Sbjct: 352 TPSGLITPVIRNTHALGLAEI 372
>UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=11;
Proteobacteria|Rep: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - Brucella
melitensis
Length = 421
Score = 58.4 bits (135), Expect = 1e-07
Identities = 47/159 (29%), Positives = 77/159 (48%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 AIETATVKVPPQDYSKEI-AGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMS 250
A A V P + SK I G + V R+ IA+RL +A+ T + ++
Sbjct: 172 AAAAAPVAAPAEVSSKAIPVGIGEYEAVPHTSMRRTIARRLLEAKTTVPHFYLNVDCEID 231
Query: 251 HIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISV 430
++A R + + ++ S ++ + +KA+A AL P N + + ++ VDI+V
Sbjct: 232 ALLALRSQINEK--REGSARISVNDFVIKASAAALRRVPDANVIWTDEALLKLKDVDIAV 289
Query: 431 AVATPKGLVVPVIRNVQNMTYADIRAH-HSWASGKSENR 544
AVAT GL+ P+IR+ M+ I A S A+ ENR
Sbjct: 290 AVATEGGLITPIIRSADQMSLGAISAQMKSLAARARENR 328
>UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=103;
Proteobacteria|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Shewanella oneidensis
Length = 677
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/89 (38%), Positives = 51/89 (57%), Gaps = 3/89 (3%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHS-IKLGLMSPFVKAAANALMDQPVVNAVIEEN- 394
+T F+E D++ + FRK+ D KK + K+ + +KA A L PV N+ + +
Sbjct: 473 VTQFDEADITEMEEFRKQQNDAAAKKKADYKITPLVFMMKAVAKTLQQFPVFNSSLSSDG 532
Query: 395 -EIIYRDYVDISVAVATPKGLVVPVIRNV 478
+I + Y I VAV TP GLVVPV+R+V
Sbjct: 533 ESLIQKKYFHIGVAVDTPNGLVVPVVRDV 561
>UniRef50_A6PJ30 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Shewanella sediminis
HAW-EB3|Rep: Catalytic domain of components of various
dehydrogenase complexes - Shewanella sediminis HAW-EB3
Length = 544
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/147 (27%), Positives = 80/147 (54%), Gaps = 3/147 (2%)
Frame = +2
Query: 77 IETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRI-AQRLKDAQNTNAMLTTFNEIDMSH 253
+ ++T+ P + G +T RV+ RG + + A+ + ++ +T T EID++
Sbjct: 290 VSSSTLSAPGMNTGSTDGG-QTIDRVEPIRGVKAVMAKMMTESVSTIPHFTYCEEIDLTE 348
Query: 254 IMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDIS 427
++ R+ ++ +KL +M F+K+ + AL PV+N+ + E+ E+ Y +I
Sbjct: 349 LVTLRESMKKKYSTDE-LKLTMMPFFMKSMSLALKQFPVINSRVNEDCSELTYLSSHNIG 407
Query: 428 VAVATPKGLVVPVIRNVQNMTYADIRA 508
+AV + GL+VP +++VQN + +I A
Sbjct: 408 MAVDSKVGLLVPNVKDVQNKSILEIAA 434
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/111 (30%), Positives = 59/111 (53%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA + + TT E+DM ++A R+++ +F ++ I+L + + V+A A
Sbjct: 215 RRVIADHMVRSLRDAPQATTVFEVDMGRVLAHRERYRSSF-EQQGIRLTVTAYIVQAVAT 273
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
AL P +N ++ II + I +AVA GL+VPV+R+ + A I
Sbjct: 274 ALRRVPALNTRFTDDGIITYRRIHIGIAVALDDGLIVPVLRDADEKSLAGI 324
>UniRef50_A4SZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes precursor; n=1; Polynucleobacter
sp. QLW-P1DMWA-1|Rep: Catalytic domain of components of
various dehydrogenase complexes precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 472
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/94 (36%), Positives = 52/94 (55%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 400
+T ++ D++ + FR L+ KK ++K+ L++ +KAA AL P NA ++ E+
Sbjct: 272 VTYHDDADITDLEKFRSD-LNKEGKKDAVKITLLAFLIKAAVAALKKYPTFNASLDGEEL 330
Query: 401 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
I + Y I AV T GLVVPVIRN +I
Sbjct: 331 ILKKYCHIGFAVDTNIGLVVPVIRNADQKGILEI 364
>UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 549
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/113 (32%), Positives = 62/113 (54%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+RL +++ T L ++ + ++AFR + ++H +K+ + +KA A
Sbjct: 357 RKVIAKRLLESKQTTPHLYLSQDVILDPLLAFRNE----LKEQHGVKVSVNDIVIKAVAL 412
Query: 350 ALMDQPVVNAVIEENEIIYRDYV--DISVAVATPKGLVVPVIRNVQNMTYADI 502
AL + P NA ++ + V DIS+AVAT KGL+ P+IRN T + I
Sbjct: 413 ALRNVPEANAYWNNDKEQAQKCVSVDISIAVATEKGLMTPIIRNADQKTISAI 465
>UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=10; Rickettsia|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rickettsia conorii
Length = 412
Score = 58.4 bits (135), Expect = 1e-07
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRG-RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH 277
P ++K ++ E R+ N R+ IA+RL +++ T E ++ ++ R+
Sbjct: 170 PSTAHNKIVSRNPEEYRLVPNNNIRKIIAKRLLESKQTVPHFYLSIECNVDKLLDIREDI 229
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLV 457
F++ S ++ + + A A AL + P NA E+ I Y + VDISVAVA GLV
Sbjct: 230 NKFFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVDISVAVAIENGLV 289
Query: 458 VPVIRNVQNMTYADI 502
P+++N ++
Sbjct: 290 TPIVKNANQKNILEL 304
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 58.0 bits (134), Expect = 1e-07
Identities = 34/129 (26%), Positives = 67/129 (51%), Gaps = 3/129 (2%)
Frame = +2
Query: 125 IAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK-HLDTFTKKH 301
++ ++RV + R++IA+++ ++ T E+D + ++A R + +
Sbjct: 177 VSSGAADERVPLRGLRKKIAEKMVRSKFTAPHFAFVEEVDATELVALRARLNAQLAAAGE 236
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRN 475
+IKL + +KA AL P +NA +E E++ R +I +A ATP GL V V+++
Sbjct: 237 NIKLNYLPFIIKATVAALKKFPHLNANFDEASQELVVRGEFNIGMAAATPDGLTVAVVKS 296
Query: 476 VQNMTYADI 502
+T A++
Sbjct: 297 ADRLTLAEL 305
>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
complex E2 component - Vesicomyosocius okutanii subsp.
Calyptogena okutanii (strain HA)
Length = 507
Score = 58.0 bits (134), Expect = 1e-07
Identities = 40/138 (28%), Positives = 75/138 (54%), Gaps = 2/138 (1%)
Frame = +2
Query: 95 KVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK 274
K P D+SK T T +K++R + + L + +T F+E++++ + A+R++
Sbjct: 273 KPPIIDFSK-FGNTET---IKLSRINKLSGKHLTTCWLSIPHVTQFDEVNINQMEAYRQE 328
Query: 275 HLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPK 448
K + IKL + +KA L + NA ++E+ +I + Y ++ +A+ TPK
Sbjct: 329 Q-----KANGIKLTPLVFIMKALVRTLKNHLRFNASLDESGENLIIKKYFNLGIAMDTPK 383
Query: 449 GLVVPVIRNVQNMTYADI 502
GL+VPVIR+V+ + D+
Sbjct: 384 GLIVPVIRDVEKKSLTDL 401
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 58.0 bits (134), Expect = 1e-07
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 3/139 (2%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R E+R+ + R+ A + + T +T F ID++ M + L + IKL
Sbjct: 313 RGEERIPVRGVRRETAAAMVRSAFTIPHVTEFVTIDVTPSMETLDR-LRNRPEFAGIKLS 371
Query: 317 LMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMT 490
++ KA AL P+VN+ ++ +EI+ R YV++ +A ATP+GLVVP I++ ++
Sbjct: 372 PLTLTAKAVLLALRRYPLVNSYWDDASDEIVVRHYVNLGIATATPRGLVVPNIKDADRLS 431
Query: 491 YADI-RAHHSWASGKSENR 544
D+ RA + A+ E R
Sbjct: 432 LIDLARAINELAATAREGR 450
>UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=47; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Azotobacter vinelandii
Length = 638
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/151 (30%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
Frame = +2
Query: 98 VPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH 277
+PP D++K G E V M R Q A L + +T F D++ + AFR
Sbjct: 399 IPPVDFAKY--GEIEE--VPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQ 454
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKG 451
+K +KL ++ +KA A L + P N+ + + +I + YV I AV TP G
Sbjct: 455 -KAVAEKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDG 513
Query: 452 LVVPVIRNVQNMTYADIRAHHSWASGKSENR 544
L+VPVIRNV + + A + + K+ ++
Sbjct: 514 LLVPVIRNVDQKSLLQLAAEAAELAEKARSK 544
>UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;
Bacteria|Rep: Dihydrolipoamide acyltransferases -
Thermoanaerobacter tengcongensis
Length = 219
Score = 57.2 bits (132), Expect = 3e-07
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +2
Query: 158 MNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVK 337
M+ R+ I+QR+K + +T ++D++ ++ R + K K K
Sbjct: 1 MDTMRRTISQRMKKSWTEIPHVTEDIKVDVTELVNLR----ENLNKSGEHKFTYTDLIAK 56
Query: 338 AAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHS 517
A AL PV+N IE +EII +++ +AVA GL+VPV++N +N + ++
Sbjct: 57 ACVIALKKNPVLNWSIEGDEIIKNPNINLGIAVALEDGLIVPVVKNAENKSLLELSKEIK 116
Query: 518 WASGKS-ENR*AHDRKNG 568
S K+ EN+ D G
Sbjct: 117 ELSEKARENKLTPDEITG 134
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/133 (27%), Positives = 64/133 (48%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
Q + + R+ IAQ + + E+D ++++ R H ++F + L +
Sbjct: 213 QSIPVKGVRKAIAQNMVTSVTEIPHGWMMLEVDATNLVKTRNHHKNSFKENEGYNLTFFA 272
Query: 326 PFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIR 505
FVKA A AL P++N+ + EII ++IS+AVA L VPVI++ + I
Sbjct: 273 FFVKAVAEALKSNPLLNSSWDGEEIILHKDINISIAVADEDKLYVPVIKHADEKSIKGIA 332
Query: 506 AHHSWASGKSENR 544
+ + K+ N+
Sbjct: 333 REINELALKARNK 345
>UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Baumannia cicadellinicola str. Hc (Homalodisca
coagulata)|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Baumannia cicadellinicola subsp. Homalodisca coagulata
Length = 358
Score = 57.2 bits (132), Expect = 3e-07
Identities = 33/89 (37%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFT-KKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN- 394
+T F+E +++ + FRK+ T KK +IK+ L+ +KA + AL P+ N+ + E+
Sbjct: 154 VTQFHEANITKLEKFRKEQNSTEEIKKLNIKITLLIFVMKAVSKALEIFPLFNSSLSEDG 213
Query: 395 -EIIYRDYVDISVAVATPKGLVVPVIRNV 478
++I + Y++I +AV TP GL+VPV NV
Sbjct: 214 TKLICKKYINIGIAVDTPSGLLVPVCHNV 242
>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
component, dihydrolipoamide succinyltransferase; n=2;
Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
succinyltransferase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 431
Score = 57.2 bits (132), Expect = 3e-07
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E R M R+ IA R D Q +T F+ +D+ ++ RK + I+L +
Sbjct: 200 EGRQPMAPVRKAIA-RAMDRQAAIPTVTNFDSVDVRKLVGHRKAFKEMARDDKGIRLTYL 258
Query: 323 SPFVKAAANALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRN 475
+ VKA A P +NA ++ EI+Y D V++ +AV P GL VPVI+N
Sbjct: 259 AYAVKALAAVAKKFPELNASVDMKAQEIVYHDDVNMGIAVDAPTGLFVPVIKN 311
>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase family protein; n=1;
Tetrahymena thermophila SB210|Rep: pyruvate
dehydrogenase complex dihydrolipoamide acetyltransferase
family protein - Tetrahymena thermophila SB210
Length = 646
Score = 56.8 bits (131), Expect = 3e-07
Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 2/138 (1%)
Frame = +2
Query: 95 KVPPQDYSKEIA--GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFR 268
K PQ E+ G Q++ + R+ IA+RL ++ T ++ M ++ R
Sbjct: 400 KPAPQQPKVEVVVQGGVEYQKIPITPMRKTIAERLVQSKTTVPHFYLNIDVQMDEVLHLR 459
Query: 269 KKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPK 448
K T ++ + K+ + VKA+A AL D P VN+ + I + D++VAV+T
Sbjct: 460 K----TLNEQSTSKISVNDLIVKASALALRDMPGVNSQWHGDHIRQFKHADVAVAVSTKT 515
Query: 449 GLVVPVIRNVQNMTYADI 502
GL+ P++ N + + + I
Sbjct: 516 GLITPIVFNAETLGLSQI 533
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 56.8 bits (131), Expect = 3e-07
Identities = 42/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 95 KVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK 274
+V P Y K+ G +E V + R+ IA+RL +++ T + + +++ I+ RK+
Sbjct: 249 RVAPPSY-KQTEGMFSE--VDLTGMRKVIAKRLTESKTTIPHYYSMVDCELTEIVRLRKQ 305
Query: 275 HLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGL 454
KK +IK+ + +KAAA AL P VN +DISVAVAT GL
Sbjct: 306 -----LKKDNIKVSVNDFIIKAAAMALKQVPEVNVTWNGQSATPLSSIDISVAVATDGGL 360
Query: 455 VVPVIRNVQNMTYADIRAH 511
+ P+++ +I A+
Sbjct: 361 ITPIVKGADAKGLMEISAN 379
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 56.8 bits (131), Expect = 3e-07
Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 4/147 (2%)
Frame = +2
Query: 71 QAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMS 250
+A + A K P K + + M+ R+ I++ + ++ T T +IDM+
Sbjct: 214 EAAKPAEAKAPAAKEEKVVDLAEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMT 273
Query: 251 HIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM--DQPVVNA--VIEENEIIYRDYV 418
++A RKK +D K +K+ A LM + +NA + + N+I +V
Sbjct: 274 EMIALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFV 333
Query: 419 DISVAVATPKGLVVPVIRNVQNMTYAD 499
++ +AV GL+VPVI M+ +D
Sbjct: 334 NLGIAVGLDDGLIVPVIHGADKMSLSD 360
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 56.8 bits (131), Expect = 3e-07
Identities = 38/145 (26%), Positives = 66/145 (45%)
Frame = +2
Query: 68 AQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
A A A PPQ E R + V + R+ IA+RL A+ ID
Sbjct: 183 AAAKAPAPAAAPPQP---EFEDLRASEEVPVTNIRRVIARRLTQAKQEIPHFYLRRRIDA 239
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDIS 427
+ FR + ++ +K+ + VKA A L D P VN+ +++++ +++
Sbjct: 240 EALREFRAQ-INEQLAPTGVKVSVNDLIVKAVATVLRDHPEVNSSWVDDKLLRHKRINVG 298
Query: 428 VAVATPKGLVVPVIRNVQNMTYADI 502
+AVA GLVVPV+ + + +++
Sbjct: 299 IAVAVDTGLVVPVLHDADTLALSEV 323
>UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1;
gamma proteobacterium HTCC2207|Rep: Dihydrolipoamide
acetyltransferase - gamma proteobacterium HTCC2207
Length = 496
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/144 (25%), Positives = 68/144 (47%)
Frame = +2
Query: 71 QAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMS 250
+A+ K+P Q S + T ++ R+ IA RL+ ++ T + ++
Sbjct: 248 EAVAALKNKIPTQTDSNTTVSSNTVASQPISGMRKTIAARLQASKQTAPHFRVHIDAEID 307
Query: 251 HIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISV 430
++A RK+ + T K+ + VKA A+AL+ P +N + ++ Y DISV
Sbjct: 308 ALLAVRKQINSSNT---DAKVSVNDFIVKACASALIKVPALNVQFDGEQLSYFSNADISV 364
Query: 431 AVATPKGLVVPVIRNVQNMTYADI 502
AVA GL+ P++ + + +I
Sbjct: 365 AVAIDDGLITPIVSDANHKGLVEI 388
>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex (E2)
protein; n=1; Nitrosomonas europaea|Rep: AceF;
dihydrolipoamide acetyltransferase component of pyruvate
dehydrogenase complex (E2) protein - Nitrosomonas
europaea
Length = 453
Score = 56.4 bits (130), Expect = 4e-07
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 4/89 (4%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIE---- 388
+T F+E D++ + A RK H +T + + KL +++ +KA AL P NA ++
Sbjct: 249 VTQFDEADVTDLEALRKNHNET-RQNNGTKLTILAFLIKAVTAALKKFPEFNASLDNSTT 307
Query: 389 ENEIIYRDYVDISVAVATPKGLVVPVIRN 475
E+++I + Y + A TP GLVVPVIR+
Sbjct: 308 ESQLIIKRYYHLGFAADTPNGLVVPVIRD 336
>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Gammaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Acinetobacter sp. (strain ADP1)
Length = 513
Score = 56.4 bits (130), Expect = 4e-07
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
+ MN R+ IA RL+ A+ E+++ + A R++ DT + +KL +
Sbjct: 290 IAMNAMRKAIASRLQLAKRNAPHFRLSIEVNVEALQALRQQINDTVPQ---LKLSINDML 346
Query: 332 VKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+KAAA AL+ P VN +E +I+ DISVAVA GL+ P+++ + A I
Sbjct: 347 IKAAAAALIKVPEVNVQYDEQKQQILQFKDADISVAVAIENGLITPIVKAANQKSLATI 405
>UniRef50_Q1AZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 396
Score = 56.4 bits (130), Expect = 4e-07
Identities = 27/91 (29%), Positives = 52/91 (57%)
Frame = +2
Query: 236 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 415
++D S ++ R++ + H + L ++A A A ++P+ N+ + + EI+ +
Sbjct: 201 QLDASALVGRRRELAGQIKRSHGVDLSYTDLLLEAVAGAAGEEPLANSSLVDGEILLYED 260
Query: 416 VDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
V++SVAVAT GL+VPV+R Q + ++ A
Sbjct: 261 VNVSVAVATGSGLLVPVVRWAQALELGELAA 291
>UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2 subunit; n=1; Stappia aggregata IAM
12614|Rep: Branched-chain alpha-keto acid dehydrogenase
E2 subunit - Stappia aggregata IAM 12614
Length = 301
Score = 56.4 bits (130), Expect = 4e-07
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 2/125 (1%)
Frame = +2
Query: 110 DYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTF 289
D + G TE+ V +R Q AQ + A +T + +M+ I A RK+ L T
Sbjct: 64 DVDHALYGPVTEEPV--SRFAQVAAQNMAAAHRLIPAVTHHDRAEMTAIEALRKQ-LRTE 120
Query: 290 TKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVP 463
+ +KL ++ KA + AL + P NA + + + +DYV + VAV T GL+VP
Sbjct: 121 AGERGVKLTALAFHAKALSKALREFPKFNASLSSDGKTLFLKDYVHLGVAVDTAHGLMVP 180
Query: 464 VIRNV 478
VIR+V
Sbjct: 181 VIRDV 185
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 56.4 bits (130), Expect = 4e-07
Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 2/121 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+RV + R+ A+ L A ++ + D++ + AFR+KH + L ++
Sbjct: 210 ERVPLRSVRRATAKHLARAWAEIPHVSHQDVADITELDAFRRKHKAEIREAGGA-LNMIV 268
Query: 326 PFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
+KAA AL P NA I E EI+++ Y +I VAV T +GL+VPVIR+V + +
Sbjct: 269 FVLKAAVAALKAFPGFNASIDPEREEIVFKRYYNIGVAVDTDRGLIVPVIRDVDRKSVRE 328
Query: 500 I 502
+
Sbjct: 329 L 329
>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
component; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase complex, E2 component - Aeropyrum pernix
Length = 412
Score = 56.4 bits (130), Expect = 4e-07
Identities = 38/135 (28%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
Frame = +2
Query: 86 ATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAF 265
A + P+ + E+R+ + ++ +AQ + +++ E+D + +
Sbjct: 159 AMLATAPKPEAPPPVAEEAEERIPVRGIKRSMAQSMSLSKSKIPHAYIAEEVDFTELSKL 218
Query: 266 RKKHLDTFTKKHSIKLGLMSPFV-KAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAV 436
R+ L ++ ++L + PFV KA A A+ P+VN+ +E EI+ + V+I AV
Sbjct: 219 REA-LKRDAEEKGVRLTYL-PFVFKAVAKAIRKYPLVNSEFDEEKMEIVVKKAVNIGFAV 276
Query: 437 ATPKGLVVPVIRNVQ 481
TP GLVVPV++NV+
Sbjct: 277 DTPHGLVVPVVKNVE 291
>UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=7; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Pseudomonas
aeruginosa
Length = 547
Score = 56.4 bits (130), Expect = 4e-07
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 2/151 (1%)
Frame = +2
Query: 98 VPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH 277
+P D+SK + V M R Q A L + +T F++ D++ + AFR
Sbjct: 308 IPEVDFSK----FGEVEEVAMTRLMQVGAANLHRSWLNVPHVTQFDQSDITDMEAFRVAQ 363
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKG 451
+K +KL ++ +KA A+ L + P N+ + + +I + YV I AV TP G
Sbjct: 364 -KAAAEKAGVKLTVLPILLKACAHLLKELPDFNSSLAPSGKALIRKKYVHIGFAVDTPDG 422
Query: 452 LVVPVIRNVQNMTYADIRAHHSWASGKSENR 544
L+VPVIR+V + + A + + K+ N+
Sbjct: 423 LLVPVIRDVDRKSLLQLAAEAADLADKARNK 453
>UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=11; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Haemophilus
influenzae
Length = 567
Score = 56.4 bits (130), Expect = 4e-07
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTK-KHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN- 394
+T F++ D++ + AFRK+ K K +K+ + +KA A AL P N+ I E+
Sbjct: 363 VTHFDKADITDLEAFRKEQNALREKQKLGVKITPVVFIMKAVAKALEAYPRFNSSITEDA 422
Query: 395 -EIIYRDYVDISVAVATPKGLVVPVIRNV 478
+I + Y++I VAV TP GLVVPV +NV
Sbjct: 423 QRLILKKYINIGVAVDTPNGLVVPVFKNV 451
>UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Leptospira|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2 -
Leptospira interrogans
Length = 458
Score = 56.0 bits (129), Expect = 6e-07
Identities = 33/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 137 RTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
R ++++++ R+ IA RL + +T E+D + + R + + S K+
Sbjct: 228 RQDRKLEITGMRKTIASRLAHSTSTIPHFYLTLELDATPLDTLRNSYNKDLKLEGSSKIS 287
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
L +KA + +L + P VN+ E+ I+ +DI VAV+ GL+ P IRN + +
Sbjct: 288 LNDLIIKACSLSLKEVPEVNSSWREDHILEHGRIDIGVAVSIEGGLITPYIRNADQKSVS 347
Query: 497 DI 502
+I
Sbjct: 348 EI 349
>UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2
component; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Dihydrolipoamide
acyltransferase E2 component - Candidatus Sulcia
muelleri str. Hc (Homalodisca coagulata)
Length = 371
Score = 56.0 bits (129), Expect = 6e-07
Identities = 35/123 (28%), Positives = 64/123 (52%)
Frame = +2
Query: 134 TRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKL 313
T + V + R+ I++RL +++ + + F E+ M +++ R + KK+ K+
Sbjct: 144 TISSNEVNHSNIRKIISKRLINSKIESPHYSLFIEVIMDNLIKLRDSINE---KKYLDKI 200
Query: 314 GLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 493
VKA+A A+ + P +N+ E I+Y + ++I +AVA GL+VPVI V +
Sbjct: 201 SFNDLIVKASALAIKENPKINSSWTEKSILYHNNINIGIAVALEDGLIVPVINQVNEKSL 260
Query: 494 ADI 502
I
Sbjct: 261 RQI 263
>UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1;
Spiroplasma citri|Rep: Putative uncharacterized protein -
Spiroplasma citri
Length = 992
Score = 56.0 bits (129), Expect = 6e-07
Identities = 39/129 (30%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Frame = +2
Query: 122 EIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH 301
E G T + +K+ R Q + +Q LT +EIDMS I+ ++K L H
Sbjct: 757 EPQGLETREEIKLTR--YPAIQSMIMSQAHVPPLTINSEIDMSSIIDQQRK-LKNANADH 813
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRN 475
++ MS VKA + L + P +N+ + N+I+ ++ I +A T +GLV+PVI+
Sbjct: 814 GVRFSTMSFLVKAVSLVLSEYPKLNSYYDSKTNQIVIKNSQHIGLATETSEGLVIPVIKF 873
Query: 476 VQNMTYADI 502
+ M+ I
Sbjct: 874 AERMSLKQI 882
>UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2
component, dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pyruvate
dehydrogenase complex , E2 component, dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 442
Score = 56.0 bits (129), Expect = 6e-07
Identities = 34/130 (26%), Positives = 62/130 (47%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
+ M + RQ IA R+ A ++ +I+M +M R + +++ +
Sbjct: 221 IPMTQMRQAIANRMVQASAGVPVIYLTTKIEMDRLMDLRAQ----INSMEGVRISINDFI 276
Query: 332 VKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAH 511
VKA +L P +N + ++I+ + VDISVAV+ P GL+ P++R+ + A I
Sbjct: 277 VKACGLSLAKFPAMNGAFQGDKIVQFNDVDISVAVSIPDGLITPIVRSADSKGLASISKD 336
Query: 512 HSWASGKSEN 541
GK+ +
Sbjct: 337 VKSLVGKARS 346
>UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1;
Dictyostelium discoideum AX4|Rep: Dihydrolipoyl
transacylase - Dictyostelium discoideum AX4
Length = 517
Score = 56.0 bits (129), Expect = 6e-07
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E RV + G ++I R +A + E M + R K + + IKL +
Sbjct: 286 ETRVPIT-GIRKIMVRSMNAACSVPHFGFTEEYIMDSLSDLRNK-VKPLAAEKGIKLSYL 343
Query: 323 SPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+KAA+ +L+ PV+N+ I ++ EIIY++Y +I +A+ +P+GL+VP I+NV++ +
Sbjct: 344 PFIIKAASLSLLRYPVLNSSISQDQTEIIYKNYHNIGIAMDSPQGLLVPNIKNVESKSIF 403
Query: 497 DI 502
+I
Sbjct: 404 EI 405
>UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=42;
Bacteria|Rep: Dihydrolipoamide acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 548
Score = 55.6 bits (128), Expect = 8e-07
Identities = 29/94 (30%), Positives = 51/94 (54%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 400
+T +E D++ + A R + L+ +K +K +++ +KA AL P NA ++ + +
Sbjct: 348 VTNNDEADITELEALRVQ-LNKEHEKAGVKFTMLAFVIKAVVAALKKFPTFNASLDGDNL 406
Query: 401 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+++ Y + A TP GLVVPVIR+ DI
Sbjct: 407 VFKQYYHVGFAADTPNGLVVPVIRDADKKGLVDI 440
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 55.6 bits (128), Expect = 8e-07
Identities = 45/156 (28%), Positives = 71/156 (45%)
Frame = +2
Query: 74 AIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSH 253
A E T K PQ + E E+ K++ R+ IA+RL +++ T +I +
Sbjct: 218 ASEEKTAKPAPQ--APEHGAPFEEE--KLSNVRKVIARRLTESKQTVPHYYLTMDIVLDP 273
Query: 254 IMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVA 433
++ RK+ L+ + +KL + +KA A AL+ P N + + DISVA
Sbjct: 274 LLKLRKE-LNASLEPDGVKLSVNDLLIKALARALIRVPQCNVSYHGDTMRKYSRADISVA 332
Query: 434 VATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSEN 541
VA P GL+ PVI A I +GK+ +
Sbjct: 333 VAAPSGLITPVITEADTKGLAQISKEMKELAGKARD 368
>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
AceF - Mycoplasma gallisepticum
Length = 440
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/129 (24%), Positives = 71/129 (55%), Gaps = 3/129 (2%)
Frame = +2
Query: 125 IAGTRTEQRVKMNRGRQRIAQRLKDA-QNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH 301
+A E ++ R+ IA+ + A + A + TFN D++ ++++RK+ D +
Sbjct: 204 VAANDNETYKEITSIRKAIAKAMTTAHEEIPATVLTFN-FDVTKLVSYRKQVKDAVLASY 262
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRN 475
++KL + +KA A++ P+ N+ ++ N ++ + +++ +AV T GL+VP I++
Sbjct: 263 NVKLSFLPFLLKAITKAVVAHPIFNSHYDKASNRLVLKKKINLGIAVDTADGLMVPNIKS 322
Query: 476 VQNMTYADI 502
Q+ + ++
Sbjct: 323 AQDKSVIEL 331
>UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E2
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 348
Score = 55.2 bits (127), Expect = 1e-06
Identities = 35/118 (29%), Positives = 63/118 (53%), Gaps = 2/118 (1%)
Frame = +2
Query: 155 KMNRGRQRIAQRLKDAQNTNAMLTTFN-EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
K N R +A+R+ ++ +A + TFN E+D + + R K +DT + +KL +
Sbjct: 125 KPNPMRATVAKRMSESY-FSAPVFTFNIEVDATELKVLRAKLIDTVKESTGVKLTMTDLI 183
Query: 332 VKAAANALMDQPVVNAVIEENEII-YRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
V A + L + +N+ + I Y+D V+I++AV +GL VPV++N + +I
Sbjct: 184 VMAVSKILPNHQALNSAWTDEGIFRYKD-VNIAIAVGLDEGLYVPVVKNANKKSLKEI 240
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 55.2 bits (127), Expect = 1e-06
Identities = 36/115 (31%), Positives = 58/115 (50%)
Frame = +2
Query: 158 MNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVK 337
++R RQ A+R+ ++Q + I+M I A K + H KL + +K
Sbjct: 224 LSRLRQTAAKRMVESQQQVPPFFVTSTIEMDAIQALLPK----LREAHGGKLSVTELLLK 279
Query: 338 AAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
A A AL P +N+ ++++ V ISVAVAT GL+ PV+RN +++ I
Sbjct: 280 ACAIALKKFPALNSTFAGDKLLVHKDVHISVAVATDAGLLAPVVRNCDSLSLGAI 334
>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=62; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Escherichia coli
(strain K12)
Length = 630
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTK-KHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN- 394
+T F++ D++ + AFRK+ + K K +K+ + +KA A AL P N+ + E+
Sbjct: 426 VTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDG 485
Query: 395 -EIIYRDYVDISVAVATPKGLVVPVIRNV 478
+ + Y++I VAV TP GLVVPV ++V
Sbjct: 486 QRLTLKKYINIGVAVDTPNGLVVPVFKDV 514
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/125 (29%), Positives = 62/125 (49%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+ L ++ T T +I++ +M RK ++ + K+ + +KA A
Sbjct: 255 RKSIAKALVQSKQTVPHFYTTVDIEVDALMDLRKG-MNGSADEGDPKVSVNDFLLKACAL 313
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASG 529
AL P VN + + + + DI++AVA GL+ PV+RNV DI A +G
Sbjct: 314 ALAKHPGVNVHVSDTGVTPFEQADIAMAVAIDGGLITPVVRNVGGRGLRDIAADAKALAG 373
Query: 530 KSENR 544
K+ +R
Sbjct: 374 KARDR 378
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 54.8 bits (126), Expect = 1e-06
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 2/140 (1%)
Frame = +2
Query: 62 RHAQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEI 241
R+A+ AT P K + + V + R+ +A+++ A+ E+
Sbjct: 131 RYAEETAKATAPAPAP---KAVEKAEEAEVVPVRGIRRAVAEKMSKAKRLIPHAYHLEEV 187
Query: 242 DMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDY 415
D + ++ R++ + +K I+L L+ KA A AL + P++N+ +E N I+ +
Sbjct: 188 DFTELIKLRER-VKAEAEKRGIRLTLLPFIAKAVAMALREYPMLNSEYDEEKNAIVVKKE 246
Query: 416 VDISVAVATPKGLVVPVIRN 475
V++ + V T +GLVV V++N
Sbjct: 247 VNLGIGVDTEQGLVVVVVKN 266
>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E...; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E... - Apis mellifera
Length = 598
Score = 54.4 bits (125), Expect = 2e-06
Identities = 36/124 (29%), Positives = 62/124 (50%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G T Q + ++ R IA+RL +++ T +I + I RK+ K I
Sbjct: 364 GPSTYQDIPVSNIRSIIAKRLGESKITIPHSYATIDIKIDKINEIRKE-----LKADGIN 418
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMT 490
+ + KA A+AL++ P +N + + ++II VDIS+AVA GL+ P++ + +
Sbjct: 419 ISINDFITKATAHALVECPFINTLYKNDQIIQMPRVDISIAVAIESGLITPIVFDATAKS 478
Query: 491 YADI 502
DI
Sbjct: 479 ILDI 482
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/140 (29%), Positives = 67/140 (47%)
Frame = +2
Query: 62 RHAQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEI 241
R A+A A V V P + + G +K R+ +A+R+ ++ + A LT
Sbjct: 195 RTAEAAPAAAV-VAPAAAAADFPGASASAPLK--GVRKVVAKRMMESLTSTAQLTLNTTA 251
Query: 242 DMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVD 421
+ + I+A RKK + K+ L A + L+ PV NA +E+ + + V
Sbjct: 252 NAAGILAMRKKVKNADEALGLNKITLNDLVCFAVSRTLLKYPVFNAHLEDGVLTEFEQVH 311
Query: 422 ISVAVATPKGLVVPVIRNVQ 481
+ A TP+GL+VPVIR+ Q
Sbjct: 312 LGFACDTPRGLLVPVIRSAQ 331
>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=3; Trypanosoma|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Trypanosoma brucei
Length = 439
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/100 (32%), Positives = 57/100 (57%), Gaps = 7/100 (7%)
Frame = +2
Query: 224 TTFNEIDMSHIMAFRKKHLDTFTK-----KHSIKLGLMSPFVKAAANALMDQPVVNAVI- 385
T +E+++S ++ F+ D + K+ LM F+KAA+ +L+ P +NA +
Sbjct: 227 TACDEVEVSQLLNFQHILRDALNSSSEGVRDGSKVSLMPLFIKAASQSLLQYPELNAHVS 286
Query: 386 -EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
E +++ + I A+ TPKGLVVPV+R+VQ + A++
Sbjct: 287 SECDKLFVKKAHHIGFAMDTPKGLVVPVVRDVQQKSVAEL 326
>UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase,
carboxy-end; n=2; cellular organisms|Rep:
Dihydrolipoamide S-acetyltransferase, carboxy-end -
Sulfolobus solfataricus
Length = 177
Score = 54.0 bits (124), Expect = 2e-06
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Frame = +2
Query: 305 IKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
+K+ VK A L D P +NA +E ++I + V+I +AVA +GL+VPVIRN
Sbjct: 1 MKITYTDILVKVVAKLLRDHPYLNATLEGDQIKIIEEVNIGIAVALDQGLIVPVIRNADT 60
Query: 485 MTYADI-RAHHSWASGKSENR*AHDRKNG 568
+I + H A EN+ D +G
Sbjct: 61 KPITEIAKESHELADKARENKLNPDEVSG 89
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 2/136 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+R R+ I +++ ++ T +++ +S ++ R++ L ++ + L
Sbjct: 316 ERREPYRGVRRSIGEQMARSRREVPHATHHDQVVVSGLVEARER-LAPLAEERDVTLTYT 374
Query: 323 SPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
VK A AL PV+N + E EI+YRD +I VA AT GLVVPV+ +V
Sbjct: 375 PFVVKCVAAALDKHPVLNTALDTENEEIVYRDAHNIGVAAATDHGLVVPVVNDVDGKGLV 434
Query: 497 DIRAHHSWASGKSENR 544
++ + G++ R
Sbjct: 435 ELAGEVNDLVGRARER 450
>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
complex, dihydrolipoamide acetyltransferase component;
n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
multienzyme complex, dihydrolipoamide acetyltransferase
component - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 583
Score = 53.6 bits (123), Expect = 3e-06
Identities = 32/111 (28%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIE---- 388
+T + D++ + AFR ++ +K KL +++ +KA+ AL P N ++
Sbjct: 379 VTYHEDADITDLEAFRVA-INKENEKSGKKLTMLAFIIKASVRALQQFPEFNTSLDASGG 437
Query: 389 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSEN 541
E ++Y+ Y +I+ A TP GLVVPVI+N + +I A + K+ +
Sbjct: 438 EMSLVYKKYFNIAFAADTPNGLVVPVIKNADRKSVFEIAAESGELAKKARD 488
>UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 370
Score = 53.6 bits (123), Expect = 3e-06
Identities = 24/35 (68%), Positives = 28/35 (80%)
Frame = +2
Query: 398 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
I+YRDYVDISVAVAT KGLV PV+RN ++M I
Sbjct: 228 IVYRDYVDISVAVATEKGLVTPVVRNTESMDLVGI 262
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 53.2 bits (122), Expect = 4e-06
Identities = 38/113 (33%), Positives = 58/113 (51%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+RL ++ T IDM +A R K ++ F +K+ +KA A
Sbjct: 335 RKVIAKRLSESLFTAPHFYLTMSIDMDGAIAARTK-INEFAP---VKISFNDMVLKAVAI 390
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
AL P VN+ ++I Y ++V+I VAVA GL+VPV+R + + I A
Sbjct: 391 ALKQHPAVNSSWLGDKIRYNEHVNIGVAVAVEDGLLVPVVRFADGKSLSHISA 443
>UniRef50_A4XEQ9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Sphingomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 480
Score = 53.2 bits (122), Expect = 4e-06
Identities = 35/113 (30%), Positives = 54/113 (47%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ +A+RL +A+ T + +M RK T K + VKA A
Sbjct: 265 RKVVARRLTEAKQTIPHFYLRVSASVDALMDLRK----TANLVLGTKASINDYLVKAVAL 320
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
AL+ P VN + + + + D+++AVA+PKGLV P++R M A I A
Sbjct: 321 ALVRHPDVNVQVHGDSVHSFPHADVAIAVASPKGLVTPIVRQADRMHIAQIAA 373
>UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=6; Bilateria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Caenorhabditis elegans
Length = 507
Score = 53.2 bits (122), Expect = 4e-06
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 3/120 (2%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH---LDTFTKKHSIKLGLM 322
+ ++ R+ IA+RL ++++T +EI + ++ R+K L T + K+ +
Sbjct: 278 IPLSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQATKISIN 337
Query: 323 SPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+KA+A A P N+ ++ I +VD+SVAV+TP GL+ P+I N A I
Sbjct: 338 DFIIKASALACQRVPEANSYWMDSFIRENHHVDVSVAVSTPAGLITPIIFNAHAKGLATI 397
>UniRef50_P09062 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=27; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas putida
Length = 423
Score = 53.2 bits (122), Expect = 4e-06
Identities = 37/106 (34%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R++IAQR++DA+ A + EID++ + A R++ L++ KL L+ V+A
Sbjct: 203 RRKIAQRMQDAKRRVAHFSYVEEIDVTALEALRQQ-LNSKHGDSRGKLTLLPFLVRALVV 261
Query: 350 ALMDQPVVNAVI-EENEIIYR-DYVDISVAVATPKGLVVPVIRNVQ 481
AL D P +NA +E +II R V + +A GL+VPV+R+ +
Sbjct: 262 ALRDFPQINATYDDEAQIITRHGAVHVGIATQGDNGLMVPVLRHAE 307
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 53.2 bits (122), Expect = 4e-06
Identities = 38/116 (32%), Positives = 64/116 (55%), Gaps = 2/116 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
EQ V + R++IAQ+++DA+ + EID++ + A R HL+ KL L+
Sbjct: 199 EQAVPVIGLRRKIAQKMQDAKRRIPHFSYVEEIDVTDLEALR-AHLNQKWGGQRGKLTLL 257
Query: 323 SPFVKAAANALMDQPVVNA-VIEENEIIYR-DYVDISVAVATPKGLVVPVIRNVQN 484
V+A AL D P +NA +E E++ R V + +A + GL+VPV+R+ ++
Sbjct: 258 PFLVRAMVVALRDFPQLNARYDDEAEVVTRYGAVHVGIATQSDNGLMVPVLRHAES 313
>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzymes; n=1; Nitrosococcus oceani ATCC
19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzymes - Nitrosococcus oceani (strain ATCC
19707 / NCIMB 11848)
Length = 447
Score = 52.8 bits (121), Expect = 5e-06
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+R M+R R++ A+++ A T +T ++ D++ + RK+ + KL L +
Sbjct: 219 EREPMSRVRRKTAEQMSQAW-TIPHVTQHDQADITRLEQARKRFAKRVEQAGG-KLTLTA 276
Query: 326 PFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
+K AA AL P N I+ + E++Y+ Y I VAV GL+VPVIR A
Sbjct: 277 IALKVAAAALQAFPRFNTSIDVDAKELVYKQYCHIGVAVDAEHGLLVPVIREADQKNIAQ 336
Query: 500 IRAHHSWASGKSENR 544
+ + + K+ +R
Sbjct: 337 LAVELTELAEKARSR 351
>UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 288
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 2/136 (1%)
Frame = +2
Query: 107 QDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDT 286
+DY +A + + + R+ IA RL +++ ++D+S + A R++ +D
Sbjct: 65 EDYEYGLARGQRAEDAATTKMRRTIASRLTESKTRTPHAYASADVDLSEVAALRRRVMDA 124
Query: 287 FTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVV 460
+K+ + + A AL + P +NA ++ R Y VD+ VAVAT GL+
Sbjct: 125 ----SGVKVSVNDCVMYAVGRALREVPELNAGWDDATGGRRAYESVDVCVAVATDDGLIT 180
Query: 461 PVIRNVQNMTYADIRA 508
P++ T +I A
Sbjct: 181 PIVTRADEKTLTEIGA 196
>UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial, putative; n=1; Babesia bovis|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial,
putative - Babesia bovis
Length = 417
Score = 52.8 bits (121), Expect = 5e-06
Identities = 41/135 (30%), Positives = 81/135 (60%), Gaps = 5/135 (3%)
Frame = +2
Query: 116 SKEIAGTRTEQRVKMNR-GRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAF--RKKHLDT 286
S+ ++G VK+N GR + + + + +T ++D++ + ++ +K+ L+T
Sbjct: 183 SQSVSGGIPGDFVKLNSVGRGMVKSMVASLEVPH--VTVGEDVDLTELKSYYLQKRALET 240
Query: 287 FTKKHSIKLGLMSPFV-KAAANALMDQPVVNAVIE-ENEIIYRDYVDISVAVATPKGLVV 460
IKL M+PF+ KA + AL + P++N+ + + I Y+++ +I+VAVAT GL+V
Sbjct: 241 -----DIKL-TMTPFLLKAFSLALSENPIMNSKFKGDGYIAYKEH-NINVAVATDHGLLV 293
Query: 461 PVIRNVQNMTYADIR 505
PVIRNV++ + +++
Sbjct: 294 PVIRNVESKSIRELQ 308
>UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=31; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Zymomonas mobilis
Length = 440
Score = 52.8 bits (121), Expect = 5e-06
Identities = 34/134 (25%), Positives = 66/134 (49%)
Frame = +2
Query: 71 QAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMS 250
QA +V P + S +I +K++ R+ IA+RL +++ + ++ M
Sbjct: 191 QASSNPSVSTP--EASGKITHDTPHNSIKLSNMRRVIARRLTESKQNIPHIYLTVDVQMD 248
Query: 251 HIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISV 430
++ R + L+ +IK+ + +KA A AL P VN + ++++ DISV
Sbjct: 249 ALLKLRSE-LNESLAVQNIKISVNDMLIKAQALALKATPNVNVAFDGDQMLQFSQADISV 307
Query: 431 AVATPKGLVVPVIR 472
AV+ GL+ P+++
Sbjct: 308 AVSVEGGLITPILK 321
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/127 (27%), Positives = 61/127 (48%)
Frame = +2
Query: 122 EIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH 301
++ G TE + ++ R+ IAQRL +++ + H+++ +KK D K
Sbjct: 174 QMHGHCTETSIPISPMRRVIAQRLVESKQNVPHFYLSVTCYLQHLLSAKKKFYDCLETKV 233
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQ 481
++ +KA A AL P +N E I +DISVAVA P GL+ P++ +
Sbjct: 234 TVN----DFVIKACAFALDKNPAMNVSWEGEFIRQNQTIDISVAVAIPDGLITPIVFSAD 289
Query: 482 NMTYADI 502
++ + I
Sbjct: 290 KLSLSSI 296
>UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 396
Score = 52.4 bits (120), Expect = 7e-06
Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 1/126 (0%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+RL ++ T + + M +++ K HL K+ + + + VK AA
Sbjct: 186 RREIAKRLLKSKTTIPHVYASTDCVMDNLLQL-KSHL----KERGLTVSVNDLLVKVAAV 240
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIR-AHHSWAS 526
L P +NAV EI Y +D++V VAT G++ PVIRN + + I H A+
Sbjct: 241 CLRKVPEMNAVWNGKEIEYLKDIDLAVDVATDVGIITPVIRNAAYLDLSQISLVAHDIAT 300
Query: 527 GKSENR 544
+N+
Sbjct: 301 RARDNK 306
>UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=40; Eukaryota|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Neurospora crassa
Length = 458
Score = 52.4 bits (120), Expect = 7e-06
Identities = 33/113 (29%), Positives = 55/113 (48%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA RLK++ N + +S ++ R+ + ++ KL + +KA
Sbjct: 236 RKTIAARLKESVTENPHFFVSTNLSVSKLLKLRQALNSSADGRY--KLSVNDFLIKAMGI 293
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
A P VN+ + I + VD+SVAVATP GL+ P+++ V+ I A
Sbjct: 294 ASKRVPTVNSSWRDGVIRQFETVDVSVAVATPNGLITPIVKGVEGKGLESISA 346
>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=3; Mollicutes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC27343 / NCTC 10154)
Length = 438
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 2/132 (1%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
V MN R+ + + + A T D++ R + L IKL ++
Sbjct: 213 VPMNGVRKATVKAMTKSHTEIAAFTGMKNTDITETHKMRTE-LKDHAAASGIKLTYLAFI 271
Query: 332 VKAAANALMDQPVVNAV--IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIR 505
+KA A +L D P +N N+I + ++I +AV TP GL+VPVI+ +++ +I
Sbjct: 272 IKAVAKSLRDMPNINVRGDFANNKIQFMHNINIGIAVDTPNGLMVPVIKGADHLSVFEIA 331
Query: 506 AHHSWASGKSEN 541
S + K+++
Sbjct: 332 IKISELANKAKD 343
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 52.0 bits (119), Expect = 1e-05
Identities = 34/124 (27%), Positives = 64/124 (51%), Gaps = 2/124 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
+Q +K+ R++IA+ + A+ T +T +EID++ + R H++ KL ++
Sbjct: 207 KQDIKVIGLRRKIAENMAHAKRTIPHITYVDEIDLTALEDLRA-HMNAKKSDDQTKLTII 265
Query: 323 SPFVKAAANALMDQPVVNAVIEENE--IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
V A +L P NA + + + D V +A ATP GL+VPVI++ +++
Sbjct: 266 PFLVLALVKSLPKFPQANAHFDTDGSLLTQHDGVHCGIAAATPNGLMVPVIKHAESLDIW 325
Query: 497 DIRA 508
++ A
Sbjct: 326 EVAA 329
>UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9;
Eurotiomycetidae|Rep: Dihydrolipoamide transacylase -
Aspergillus oryzae
Length = 476
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/100 (31%), Positives = 60/100 (60%), Gaps = 5/100 (5%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-----E 397
+E+++++I A RKK + K ++ +S +KA + AL + P++NA ++ + +
Sbjct: 272 DELNINNITALRKKLAND--PKDPRRITFLSFVIKAVSLALNEYPILNAKVDTSNPDKPQ 329
Query: 398 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHS 517
+I R +I VA+ TP+GL+VP +++V N + D+ A S
Sbjct: 330 LIMRPRHNIGVAMDTPQGLIVPNVKDVANRSIEDVAAEIS 369
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/123 (26%), Positives = 70/123 (56%), Gaps = 3/123 (2%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E+R+ + R+ +A+++ + + F E+D++ +++ R++ L ++ +KL +
Sbjct: 178 EERIPVRGIRRAVAEKMAKSASAIPHAYHFEEVDVTELVSLRER-LRQEAERLGVKLTYL 236
Query: 323 SPFV-KAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 493
PFV KA A AL + P++N+ +E EI+ + + + AV T +GL+V V+R+ +
Sbjct: 237 -PFVAKAVAVALREFPMLNSSFDEERGEIVVKRRIHLGFAVDTEQGLMVVVVRDADKKSV 295
Query: 494 ADI 502
+I
Sbjct: 296 LEI 298
>UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=46; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Homo sapiens (Human)
Length = 614
Score = 52.0 bits (119), Expect = 1e-05
Identities = 36/126 (28%), Positives = 62/126 (49%)
Frame = +2
Query: 98 VPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH 277
VPP T + ++ R+ IAQRL ++ T +++M ++ RK+
Sbjct: 372 VPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKE- 430
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLV 457
L+ + S K+ + +KA+A A + P N+ + I VD+SVAV+TP GL+
Sbjct: 431 LNKILEGRS-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLI 489
Query: 458 VPVIRN 475
P++ N
Sbjct: 490 TPIVFN 495
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/142 (24%), Positives = 72/142 (50%), Gaps = 3/142 (2%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
VK+ R R+ ++ + +++ +EI++ ++ FR + K IKL M+
Sbjct: 318 VKITRLRKAVSNAMTRSKSIIPETVLMDEINVDALVNFRNEAKGLAESK-GIKLTYMAFI 376
Query: 332 VKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIR 505
KA AL + P+ NA + +E+ + ++++ +AV TP GL+VP I+N ++ ++
Sbjct: 377 AKAVLIALKEFPMFNASFNHDTDEVYIKKFINLGMAVDTPDGLIVPNIKNADRLSVFELA 436
Query: 506 AH-HSWASGKSENR*AHDRKNG 568
+ S A + + D++ G
Sbjct: 437 SQVRSLADDTIARKISMDQQTG 458
>UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacylase;
n=2; Deuterostomia|Rep: PREDICTED: similar to
transacylase - Strongylocentrotus purpuratus
Length = 620
Score = 51.6 bits (118), Expect = 1e-05
Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 2/92 (2%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIY 406
+E+D++ ++A K H I+ F+KAA+ AL P +N ++E + Y
Sbjct: 325 DEVDVTELVAL-KSHFKAAAAARGIQFSFTPLFIKAASMALSFFPEINMSVDEQCENMTY 383
Query: 407 RDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ +I A+ +P+GL+VP ++NVQ +T ++
Sbjct: 384 KAAHNIGFAMDSPQGLIVPNVKNVQALTLMEV 415
>UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Sinorhizobium medicae WSM419
Length = 386
Score = 51.6 bits (118), Expect = 1e-05
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G R+ + R IA+ + ++ T +T E D S + R +H + +
Sbjct: 145 GEPESSRIPHSSMRAAIAEHMLNSVMTAPHVTAVFEADFSAVTRHRDEHRKKLAAR-GVN 203
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATP-KGLVVPVIRNVQNM 487
L + V A+ A+ P VN+ E+ + D ++I V ++ KGLVVPVIR QN+
Sbjct: 204 LSYTAYVVLASLAAMRAVPEVNSRWHEDALETFDDINIGVGISLGGKGLVVPVIRRAQNL 263
Query: 488 TYADIRA 508
+ A+I A
Sbjct: 264 SLAEIAA 270
>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
component; n=1; marine actinobacterium PHSC20C1|Rep:
Putative dihydrolipoamide acyltransferase component -
marine actinobacterium PHSC20C1
Length = 480
Score = 51.6 bits (118), Expect = 1e-05
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
EQR + R+ A + + T +T F ID++ M K K ++
Sbjct: 254 EQRTPIKSVRKATAAAMVSSAFTAPHVTEFLTIDVTRTMELVAK-----LKAGGTAASVL 308
Query: 323 SPFVKAAANALMDQPVVNAV--IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+ KA + P VN+ E NEI+ YV++ +AVATP+GL+VP +++ MT A
Sbjct: 309 AVLAKALCIGVARNPSVNSRWDAEANEIVEFGYVNLGIAVATPRGLMVPNLKDADMMTLA 368
Query: 497 DI 502
++
Sbjct: 369 EL 370
>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 474
Score = 51.6 bits (118), Expect = 1e-05
Identities = 29/122 (23%), Positives = 67/122 (54%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E R + R+ + Q + + T +T + +D++ M ++ L T + +++ +
Sbjct: 241 EWREPIKGVRKMMGQAMVQSAFTLPHVTEWVTVDVTATMELVER-LKTRREFREVRVSPL 299
Query: 323 SPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+A A+ P +N+ ++ +E++Y+ YV++ +A ATP+GLVVP +++ ++MT
Sbjct: 300 LVLARAVMLAMRRTPEINSWWDDAAHEVVYKRYVNLGIAAATPRGLVVPNVKDAESMTLL 359
Query: 497 DI 502
++
Sbjct: 360 EL 361
>UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 337
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/133 (31%), Positives = 62/133 (46%)
Frame = +2
Query: 77 IETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHI 256
IE +++ + R Q + ++ R IA+RL ++ ++ + I
Sbjct: 78 IENKSIEKKSDIFGANNRSLRHHQDIPLSNIRATIAKRLTASKQQIPHEYQGVDVRIDDI 137
Query: 257 MAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAV 436
+A R+K KK + L +KAAA AL P VN V E I VDISVAV
Sbjct: 138 LALRQK-----LKKSGTAVSLNDFIIKAAALALRSVPTVN-VRWTPEGIGLGSVDISVAV 191
Query: 437 ATPKGLVVPVIRN 475
ATP GL+ P++ N
Sbjct: 192 ATPTGLITPIVEN 204
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 51.2 bits (117), Expect = 2e-05
Identities = 41/160 (25%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
Frame = +2
Query: 77 IETATVKVPPQDYSKEIA---GTRTE--QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEI 241
I VK + KE+A G E +R+ M+ R+ I+QR+K + + +T ++
Sbjct: 132 ISEQKVKTEEEGPKKEVAVIEGQALEKVERMPMDNIRKTISQRMKKSWSEIPHVTEDIKV 191
Query: 242 DMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVD 421
D++ ++ R+ +L+ + L++ KA A+ PVVN IE II ++
Sbjct: 192 DVTELVNLRE-NLNHISDNKFTYTDLIA---KACVIAIKKNPVVNWSIEGEYIIKNSSIN 247
Query: 422 ISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSEN 541
+ +AVA GL+VPV++ + ++ + S ++ N
Sbjct: 248 LGIAVALDNGLIVPVVKEADKKSLLELSKNIKELSERARN 287
>UniRef50_A5V4B2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 420
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = +2
Query: 161 NRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKA 340
+R R IAQ + ++ +T E D + IMA R+KH F + L + F+ A
Sbjct: 197 DRMRLAIAQNMLNSVTVAPHVTAMFECDFTAIMAHRRKHKAAFAAE-GANLTFTAYFIAA 255
Query: 341 AANALMDQPVVNAVIEENEIIYRDYVDISVAVAT-PKGLVVPVIRNVQNMTYADI 502
A+ P +N+ ++ + D V+I + A KGLVVPV+ Q ++ I
Sbjct: 256 CVAAMKAAPAINSRWHDDRLDIFDDVNIGIGTALGDKGLVVPVVSKCQELSLLGI 310
>UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1164
- Rattus norvegicus (Rat)
Length = 539
Score = 50.8 bits (116), Expect = 2e-05
Identities = 37/116 (31%), Positives = 60/116 (51%)
Frame = +2
Query: 128 AGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSI 307
AGT TE + + R+ IA+RL ++++T D+ ++ R+ + K I
Sbjct: 259 AGTFTE--IPASNIRKVIAKRLTESKSTVPHAYATANCDLGAVLKVRRDLV-----KDDI 311
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRN 475
K+ + ++AAA L P VN + + VDISVAVAT KGL+ P+I++
Sbjct: 312 KVSVNDFIIRAAAVTLKQMPGVNVTWDGEGPKHLPSVDISVAVATDKGLITPIIKD 367
>UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E2
component of the pyruvate dehydrogenase complex; n=2;
Moraxellaceae|Rep: Dihydrolipoamide S-acetyltransferase,
E2 component of the pyruvate dehydrogenase complex -
Acinetobacter sp. (strain ADP1)
Length = 661
Score = 50.8 bits (116), Expect = 2e-05
Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 394
+T F+ D++ + A+R F KK I L +M+ +KA A+ L ++ + ++
Sbjct: 459 VTQFDLADITELEAWRNDLKGNF-KKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGK 517
Query: 395 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
++ R + + +AVATP GL VPV+RN T I
Sbjct: 518 SVLLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQI 553
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 50.8 bits (116), Expect = 2e-05
Identities = 33/122 (27%), Positives = 63/122 (51%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E R + R++ A + + T +T F +D++ + ++ L + + +
Sbjct: 187 ETRTPIRSVRKQTAAAMVRSAFTAPHVTEFVTVDVTRSVELLER-LRGLPDFEGLSVTPL 245
Query: 323 SPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
S KA AL + P +NA +E EI+ + YV++ +A ATP+GLVVP I+ Q+++
Sbjct: 246 SLVAKAMIVALRENPSLNASWDEENQEIVTKHYVNLGIAAATPRGLVVPNIKEAQSLSLL 305
Query: 497 DI 502
++
Sbjct: 306 EL 307
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 50.8 bits (116), Expect = 2e-05
Identities = 44/143 (30%), Positives = 62/143 (43%)
Frame = +2
Query: 80 ETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIM 259
E A++ PP I TE + + R+ IA+RL +A+ T + E+D
Sbjct: 172 EAASIS-PPASRLHLIDTPYTE--IPLTNIRKVIARRLTEAKATIPHF--YLEVDCEIDE 226
Query: 260 AFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVA 439
+ + L L +KAAA AL P N ++ II VDISVAVA
Sbjct: 227 LLKSRETLNARSDGQYNLSLNDLVIKAAALALRQVPEANTAWTDDAIIQFQDVDISVAVA 286
Query: 440 TPKGLVVPVIRNVQNMTYADIRA 508
T GL+ P++R A I A
Sbjct: 287 TDGGLITPIVRQADRRGLASISA 309
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 50.8 bits (116), Expect = 2e-05
Identities = 37/134 (27%), Positives = 64/134 (47%)
Frame = +2
Query: 101 PPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHL 280
PP + +A V ++ R+ I++R+ + + E+DM +A R +
Sbjct: 217 PPAPAAVSVAQPTAGAVVPLSNMRKTISRRMIQSWQQFPHIFVSIEVDMGAALALRAQAN 276
Query: 281 DTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVV 460
++ I + M VKA A AL+ P +NA ++ II V+I++AVA GL+
Sbjct: 277 AGRPREDQISVNDM--VVKACAVALLAFPNLNASYSDDGIILHPTVNIAIAVALESGLMA 334
Query: 461 PVIRNVQNMTYADI 502
PV+ N Q+ + I
Sbjct: 335 PVVANCQDRSLGSI 348
>UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=3;
Saccharomycetales|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 482
Score = 50.8 bits (116), Expect = 2e-05
Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 2/120 (1%)
Frame = +2
Query: 128 AGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSI 307
+ T + + V ++ R I +RL + ++I +S ++ R+ T K+
Sbjct: 246 SSTASYEDVPISTMRSIIGERLLQSTQGIPSYIVSSKISISKLLKLRQSLNATANDKY-- 303
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRNVQ 481
KL + VKA A P NA NE + R + VD+SVAVATP GL+ P+++N +
Sbjct: 304 KLSINDLLVKAITVAAKRVPDANAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCE 363
>UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=2;
Apocrita|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Apis mellifera
Length = 501
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/92 (32%), Positives = 56/92 (60%), Gaps = 2/92 (2%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI-EENEII-Y 406
+E +++ ++ +R + D+ K I L M F+KAA+ AL P +N+ + EEN+ +
Sbjct: 300 DECNINRLIDYRNEVKDSL-KDEGISLSFMPFFIKAASRALEKVPQLNSWLDEENQALRV 358
Query: 407 RDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ +I +A+ T +GL+VP I++VQN+ +I
Sbjct: 359 QKSHNIGIAMDTSEGLIVPNIKDVQNLNIIEI 390
>UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Anaeromyxobacter
sp. Fw109-5
Length = 574
Score = 50.4 bits (115), Expect = 3e-05
Identities = 28/94 (29%), Positives = 51/94 (54%)
Frame = +2
Query: 221 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 400
+T +E D++ + FR + L+ K +K+ L++ +KA AL P N+ +E +++
Sbjct: 374 VTQHDEADITELERFRVE-LNQERAKEGVKVTLLAFVLKACVAALRRFPEFNSSLEGDQL 432
Query: 401 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ + Y I A TP GLVVPV+++ +I
Sbjct: 433 VLKRYFHIGFAADTPGGLVVPVVKDADRKGVLEI 466
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 50.0 bits (114), Expect = 4e-05
Identities = 31/113 (27%), Positives = 57/113 (50%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+RL +++++ + ++ ++ RK+ K +IK+ + +KA A
Sbjct: 259 RKVIAKRLTESKSSIPHAYATTDCNLGAVLQLRKE-----LAKDNIKVSVNDFIIKATAA 313
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
AL P VN + +DIS+AVAT +GL+ P+I+ + +I A
Sbjct: 314 ALKQMPNVNVTWNGEGATTLESIDISIAVATDRGLITPIIKQAASKGIQEIAA 366
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Frame = +2
Query: 131 GTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIK 310
G E+R + R+R A + + T +TF +D + M HL T +
Sbjct: 276 GPAREERTPVTGVRKRTAAAMVTSATTIPQASTFVTVDCTATMELID-HLRTTPAFAGLS 334
Query: 311 LGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
L + KA AL + P VNA +E +I+ + YV + +A AT +GL+VP ++
Sbjct: 335 LTPLVVVAKAVLAALAEFPGVNAQWDEERQQIVTKRYVHLGIAAATDRGLLVPSVKEAHR 394
Query: 485 MTYADIRA 508
++ ++ A
Sbjct: 395 LSLRELCA 402
>UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Salinibacter ruber DSM 13855|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Salinibacter ruber
(strain DSM 13855)
Length = 465
Score = 50.0 bits (114), Expect = 4e-05
Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+RL +++ + +ID+ + R+ D ++ K+ KA A
Sbjct: 245 RETIARRLAESKYSAPHYYLTVDIDVERAIEVREDLNDLAEEQGRAKISFNDFITKACAL 304
Query: 350 ALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+L D P VNA +E EI + V I +AVA +GL+ PVIR+ +++
Sbjct: 305 SLHDHPYVNAAYRPDEGEIHKHNRVHIGIAVAIDEGLITPVIRDADRKGLSEL 357
>UniRef50_A6W003 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Marinomonas|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Marinomonas sp. MWYL1
Length = 414
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/113 (30%), Positives = 62/113 (54%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQ-NTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAA 346
R++IA + D+ +T+ +T+ E+DM I+ RK F ++ +KL + F+ A+A
Sbjct: 193 RKKIANHMVDSLLHTSPHVTSVFEMDMGRIIEHRKMCKMGF-EEAGVKLTFTAYFLAASA 251
Query: 347 NALMDQPVVNAVIEENEIIYRDYVDISVAVAT-PKGLVVPVIRNVQNMTYADI 502
A+ PVVN+ ++ + + ++I V A GL+VPV++ VQ +I
Sbjct: 252 KAMQKVPVVNSRFHDDCLEIFEDINIGVGTALGDDGLIVPVVKQVQEKNLFEI 304
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDA--QNTNAMLT-TFNEIDMSHIMAFRKKHLDTFTKKHSIKLG 316
+ + +N R+ A+RL ++ Q + LT T N + + A L + + K+
Sbjct: 221 EEIPLNTIRKITARRLTESMQQAPHFYLTRTLNAEPLIDVRARLNAALSS-ADPDTAKIS 279
Query: 317 LMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
L VK AA AL P VN +++ ++ I VAVA P GL+VPVIR+ +
Sbjct: 280 LNDLIVKVAAAALRKHPEVNVSYAGEKLLQHKHIHIGVAVAIPDGLIVPVIRDADTLGIR 339
Query: 497 DI 502
+I
Sbjct: 340 EI 341
>UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_34,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 419
Score = 50.0 bits (114), Expect = 4e-05
Identities = 39/146 (26%), Positives = 75/146 (51%), Gaps = 4/146 (2%)
Frame = +2
Query: 80 ETATVKVPPQDYSK-EIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHI 256
+T + K PQ +K I +KM+ ++ + + + +A N+ L E+D++ +
Sbjct: 170 QTQSPKEQPQSSTKINIKSESASTVIKMSDFQKGMQKSMTEA-NSIPHLYLKEEVDLTEL 228
Query: 257 MAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN---EIIYRDYVDIS 427
R++ KK + M+ +K+ + AL P++N+ + E ++S
Sbjct: 229 AQMREQ-----LKKEK-NITFMTLLIKSFSLALTKYPILNSTYDPTKQFEYTQHSSHNVS 282
Query: 428 VAVATPKGLVVPVIRNVQNMTYADIR 505
VA+ +PKGLVVP I+NVQN++ + I+
Sbjct: 283 VALDSPKGLVVPNIKNVQNLSISQIQ 308
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 50.0 bits (114), Expect = 4e-05
Identities = 33/113 (29%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ I +++ +++ T +T + + ++ R K L + +KL M +KA
Sbjct: 258 RRTIGEQMAESKYTAPHVTHHDTAVIDSLVETRSK-LKARAEAEDVKLTYMPFVMKAVVA 316
Query: 350 ALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
AL + PV+N+ + E+ EI + +I VAVAT GL+VPV+ +V + +I
Sbjct: 317 ALKEFPVLNSELREDDEEIALKQDYNIGVAVATDAGLMVPVVEHVDQKSMLEI 369
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 50.0 bits (114), Expect = 4e-05
Identities = 35/126 (27%), Positives = 61/126 (48%)
Frame = +2
Query: 98 VPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH 277
+PP + T + + R+ IA+RL ++++T + D+ ++ R+
Sbjct: 260 IPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL 319
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLV 457
+ K IK+ + +KAAA L P VN + ++DISVAVAT KGL+
Sbjct: 320 V-----KDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLL 374
Query: 458 VPVIRN 475
P+I++
Sbjct: 375 TPIIKD 380
>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
Oceanobacillus iheyensis
Length = 420
Score = 49.6 bits (113), Expect = 5e-05
Identities = 33/126 (26%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +2
Query: 107 QDYSKEIAGTRTEQRVKMNRGRQR-IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLD 283
Q+ +++ E + +GR++ IA+++ + T + E+DM+ ++ FRK+
Sbjct: 180 QETEEQVDAKEEEAEIIPFKGRRKQIAKKMTTSIYTIPHVHHMEEVDMTELLEFRKEI-- 237
Query: 284 TFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLV 457
K + + + F+KA AL + P+ NA + E+ EI + + +A T +GL+
Sbjct: 238 ----KSDADISVAAFFIKALTIALKEYPIFNAKLHEEKEEIRLEKGIHMGIATDTEEGLI 293
Query: 458 VPVIRN 475
VPVI++
Sbjct: 294 VPVIQS 299
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/113 (28%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+ ++ + + A LT + + ++AFR+ L T ++ H ++L L + A A
Sbjct: 190 RKTIARNMRASLHNTAQLTLHRKAHANALLAFRRL-LKTESESHQLQLKLSVTVLIARAT 248
Query: 350 ALMDQPV--VNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
L Q V +N+ E ++ + V + +A + GLVVPVIRN +++ +
Sbjct: 249 ILALQQVGAMNSRYENGQLKEFENVHLGIATSLDDGLVVPVIRNADHLSIGQL 301
>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex -
Psychrobacter arcticum
Length = 578
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 4/94 (4%)
Frame = +2
Query: 206 NTNAMLTTFNEIDMSHIMAFR--KKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNA 379
N N L + D+S I + L K I L +++ VKA A AL P N+
Sbjct: 366 NYNTYLPQVTQFDLSDITETEQLRSELKGGMKAEGIGLTILAFIVKATAYALTQHPRFNS 425
Query: 380 VIEEN--EIIYRDYVDISVAVATPKGLVVPVIRN 475
+ ++ ++I R V++ +AVAT GL+VPVI+N
Sbjct: 426 HLSDDNTQVILRKSVNMGIAVATDDGLIVPVIKN 459
>UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Mycoplasma synoviae|Rep: Dihydrolipoamide
acetyltransferase - Mycoplasma synoviae
Length = 309
Score = 49.6 bits (113), Expect = 5e-05
Identities = 29/127 (22%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IA+ + ++ + A + ++M+ + R D+ K +K+ + +KA +
Sbjct: 88 RKAIAKAMTNSWSNVAYTNLVHRVNMTKLWDLRSSIKDSLLKSEDVKITFLPFILKAVSV 147
Query: 350 ALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWA 523
AL + P+ +A E + + + +++ AV T GL+VPVI+N ++ D+ S
Sbjct: 148 ALKEFPLFSAKYNEAKSTLDFPGVINLGFAVDTEAGLMVPVIKNANALSVLDLAREVSRL 207
Query: 524 SGKSENR 544
+ + N+
Sbjct: 208 ASAARNK 214
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 49.6 bits (113), Expect = 5e-05
Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 2/135 (1%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+R K+N+ + A+ L + +T + D++ + RK + K+ + +
Sbjct: 220 ERKKLNKLSRVSAKNLSLSWQVIPHVTQHDLADITDLETARKLFISK-PNYSGPKVTMTA 278
Query: 326 PFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYAD 499
+KA A AL + P N+ + +EI+Y++Y++I VAV T GLVVPV+++V
Sbjct: 279 LAMKAIAIALHEYPSFNSSFDSQTDEIVYKNYINIGVAVDTENGLVVPVVKDVDKKNIIT 338
Query: 500 IRAHHSWASGKSENR 544
I + + K+ +R
Sbjct: 339 IANEMNALAIKARDR 353
>UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Buchnera aphidicola|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Buchnera aphidicola
subsp. Baizongia pistaciae
Length = 410
Score = 49.6 bits (113), Expect = 5e-05
Identities = 36/135 (26%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = +2
Query: 110 DYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTF 289
+Y K+ + +++ R + R ++ L + T +T F+E D++ + FR+K+ ++
Sbjct: 168 NYYKDNVTCDDFKSIELTRTQIRSSKNLLKSWLTIPHVTQFDESDITELENFRQKY-NSD 226
Query: 290 TKKHSIKLGLMSPFVKAAANALMDQPVVNA--VIEENE--IIYRDYVDISVAVATPKGLV 457
K S KL ++ +KA + AL P N + ++N I+ ++++I + V T GL+
Sbjct: 227 LKDKSKKLTILIFVIKAVSKALEMFPKFNGRLINKDNRIAIVLNEHINIGIVVDTDDGLL 286
Query: 458 VPVIRNVQNMTYADI 502
VPVI V + I
Sbjct: 287 VPVINRVNKKNISSI 301
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 49.2 bits (112), Expect = 7e-05
Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTK--KHSIKLGLMSPFVKAA 343
R+ I +RL +++ E++M ++ R + F K + KL + VKAA
Sbjct: 260 RRTIGKRLTESKQQLPHYYVTVEVNMDRVLKLR----EVFNKAGESKTKLSVNDFIVKAA 315
Query: 344 ANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
+ AL D P N+ I DI VAVATP GL+ P+I++V A I A
Sbjct: 316 SLALADVPEANSAWLGETIRTYKKADICVAVATPNGLITPIIKDVGAKGLATISA 370
>UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=2; Dictyostelium
discoideum|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Dictyostelium
discoideum (Slime mold)
Length = 592
Score = 49.2 bits (112), Expect = 7e-05
Identities = 28/85 (32%), Positives = 44/85 (51%)
Frame = +2
Query: 299 HSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNV 478
+++K+ + VKA+ AL D PVVN+ + I +DI+VAV TP+GL P++R V
Sbjct: 414 NTVKISVNDFIVKASLPALRDNPVVNSTWTDQFIRRYHNIDINVAVNTPQGLFTPIVRGV 473
Query: 479 QNMTYADIRAHHSWASGKSENR*AH 553
I + K++N H
Sbjct: 474 DMKGLNSISTSVKQLAEKAQNGKLH 498
>UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1; Nostoc
punctiforme PCC 73102|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Nostoc punctiforme PCC 73102
Length = 367
Score = 48.8 bits (111), Expect = 9e-05
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +2
Query: 278 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVV-NAVIEENEIIYRDYVDISVAVATPKGL 454
L + KKH I +GL +K A L + P ++I++N + + +I V + KGL
Sbjct: 186 LSDYGKKHDIIIGLPELLIKITATLLSEFPFFFGSLIDDNRFMPGEVANIGVTLDLGKGL 245
Query: 455 VVPVIRNVQNMTYADI 502
+PVI+NV ++ ADI
Sbjct: 246 FIPVIKNVGEISLADI 261
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 48.8 bits (111), Expect = 9e-05
Identities = 34/136 (25%), Positives = 67/136 (49%)
Frame = +2
Query: 125 IAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS 304
+A EQR++ + Q +A+R+ A+ + E ++S ++A R++ + +
Sbjct: 179 LAPAAGEQRIEASALVQSMARRMTQAKQVPHFYLSA-EAEVSALLALRQR---LNAQADA 234
Query: 305 IKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
+L L + A A AL P N + ++ I+ +D+ VAV+T +GL+ PV+ + +
Sbjct: 235 PRLTLNHFVIAAVARALAAMPHQNRIWNDDHIVQFQGIDVGVAVSTERGLMAPVLHGLDH 294
Query: 485 MTYADIRAHHSWASGK 532
+ DI A G+
Sbjct: 295 ASLDDIAAQSGALLGR 310
>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=9; Actinobacteria
(class)|Rep: Catalytic domain of components of various
dehydrogenase complexes - Arthrobacter sp. (strain FB24)
Length = 462
Score = 48.8 bits (111), Expect = 9e-05
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = +2
Query: 143 EQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLM 322
E R + R+ A + + T T F ID++ M + L KL +
Sbjct: 232 ETRTPIKGVRKLTAAAMVSSAFTAPHATEFLTIDVTPTMELLSR-LKASRTFEGFKLTPL 290
Query: 323 SPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYA 496
+ KA AL QP +N+ +E EI+ +YV++ +A ATP+GL VP I++ +M+
Sbjct: 291 TLVAKALLIALRRQPSLNSRWDEANQEIVQYNYVNLGIAAATPRGLTVPNIKDAHSMSLT 350
Query: 497 DI 502
++
Sbjct: 351 EL 352
>UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding
protein; n=2; Ascaris suum|Rep: Dihydrolipoyl
dehydrogenase-binding protein - Ascaris suum (Pig
roundworm) (Ascaris lumbricoides)
Length = 368
Score = 48.8 bits (111), Expect = 9e-05
Identities = 43/148 (29%), Positives = 64/148 (43%), Gaps = 1/148 (0%)
Frame = +2
Query: 68 AQAIETA-TVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEID 244
AQA A PQ SK T+ + + R IA+RL +++ +ID
Sbjct: 112 AQAAPAAPAAPAEPQLISKRRPPRYTD--IPLTNMRSVIARRLCESKQGIPHTYAIQKID 169
Query: 245 MSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDI 424
++ R K KK I + + +KA A AL P +N ++ VDI
Sbjct: 170 SDNVNKLRAK-----LKKEGISVSINDFIIKACACALRAVPELNVKWMKDHAEALPNVDI 224
Query: 425 SVAVATPKGLVVPVIRNVQNMTYADIRA 508
SVAVATP GL+ P++ + + I A
Sbjct: 225 SVAVATPAGLITPIVFKADTLGVSQIGA 252
>UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransferase,
putative; n=1; Aspergillus fumigatus|Rep: 2-oxo acid
dehydrogenases acyltransferase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 460
Score = 48.8 bits (111), Expect = 9e-05
Identities = 33/97 (34%), Positives = 55/97 (56%), Gaps = 5/97 (5%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI-----EENE 397
+E+ ++ I A RKK K K+ + +KA + AL + P++NA + E+ +
Sbjct: 256 DELKINDITALRKKLASD--PKDPKKVTFLPFVIKAVSLALNEYPLLNAKVDLSIPEKPK 313
Query: 398 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
+I R +I VA+ TP+GL+VP I++V N T +I A
Sbjct: 314 LIMRPKHNIGVALDTPQGLIVPNIKDVANRTIMEIAA 350
>UniRef50_A1RJV4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=25; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Shewanella sp. (strain W3-18-1)
Length = 536
Score = 48.4 bits (110), Expect = 1e-04
Identities = 34/130 (26%), Positives = 71/130 (54%), Gaps = 3/130 (2%)
Frame = +2
Query: 128 AGTRTEQRVKMNRGRQRIAQRLK-DAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS 304
A T+ V+ RG + + R+ ++ ++ T E D++ ++A R+ ++
Sbjct: 298 AATQRADTVEPIRGVKAVMARMMVESVSSIPHFTYCEEFDLTDLVALRESMKAKYSTDE- 356
Query: 305 IKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNV 478
+KL +M F+K+ + A+ PV+N+ + + E+ Y+ +I +AV + GL+VP I++V
Sbjct: 357 VKLTMMPFFMKSMSLAISQFPVMNSQVNADCTELTYKVRHNIGMAVDSKVGLLVPNIKDV 416
Query: 479 QNMTYADIRA 508
Q+ + +I A
Sbjct: 417 QDKSILEIAA 426
>UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=29; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rhizobium meliloti
(Sinorhizobium meliloti)
Length = 447
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS---IKLGLMSPFVKA 340
R+ IA+RL +++ T + ++ +MA R + +K KL + +KA
Sbjct: 226 RKTIAKRLVESKQTIPHFYVSVDCELDALMALRAQLNAAAPEKDGKPVYKLSVNDMVIKA 285
Query: 341 AANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQ 481
A AL D P N + ++ + D+ VAV+ P GL+ P++R +
Sbjct: 286 LALALRDVPDANVSWTDQNMVKHKHADVGVAVSIPGGLITPIVRQAE 332
>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=2; Leishmania|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Leishmania major
Length = 477
Score = 48.0 bits (109), Expect = 2e-04
Identities = 31/97 (31%), Positives = 54/97 (55%), Gaps = 5/97 (5%)
Frame = +2
Query: 227 TFNE-IDMSHIMAFRKKHLDTFTK--KHSIKLGLMSPFVKAAANALMDQPVVNA--VIEE 391
TF+E +++ +M R D + K KL M F+KAA+ AL P +NA ++
Sbjct: 269 TFSEECELTRLMEVRGSLKDVVKERSKGKAKLSFMPFFLKAASIALQHHPDINAHCPVDC 328
Query: 392 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+ ++ + +I A+ TP GL+VPV+++V+ + DI
Sbjct: 329 SALVRKAAHNIGFAMDTPNGLIVPVVKHVERKSILDI 365
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 47.6 bits (108), Expect = 2e-04
Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 7/118 (5%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTF----TKKHSI---KLGLMSP 328
R+ IA+RL +A++T + ++ ++A R + T+K + KL +
Sbjct: 229 RKTIARRLVEAKSTIPHFYLTLDCELDALLALRTQINAAAPMKKTEKGDVPAYKLSVNDM 288
Query: 329 FVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+KA A AL P NA E ++ + D+ VAV+ P GL+ P+IR+ T + I
Sbjct: 289 VIKAMAMALKAVPDANASWTETAMVKHKHADVGVAVSIPGGLITPIIRHADEKTLSTI 346
>UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Acetyltransferase -
Chlamydia trachomatis
Length = 429
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ I++RL+ A+ I S ++A K+ ++ +IKL + V+A A
Sbjct: 213 REVISKRLQAAKTFIPHFYVRQRIYASPLLALLKE-----LQEQNIKLSINDCIVRACAL 267
Query: 350 ALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIR 472
AL + P +N+ +N+II +DIS+AVA P G++ P++R
Sbjct: 268 ALKEFPEINSGFNSVDNKIIRFSTIDISIAVAIPDGVIAPIVR 310
>UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Novosphingobium aromaticivorans|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Sphingomonas aromaticivorans
Length = 406
Score = 47.6 bits (108), Expect = 2e-04
Identities = 34/106 (32%), Positives = 60/106 (56%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ IAQR+ +A LT E+D++ + A R+ + + LG+++ +AA
Sbjct: 196 RRTIAQRMVEAAAIPT-LTADMEVDLTALFARRR----SVEGNGASVLGMIA---EAAIA 247
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
AL+ +NA E+ ++ V + +AV TP+GLVVPV+RN +++
Sbjct: 248 ALLQHRRLNAHWREDAMVQFGAVHLGIAVDTPEGLVVPVVRNAESL 293
>UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n=3;
Bacteria|Rep: Dihydrolipoamide S-acetyltransferase -
Candidatus Pelagibacter ubique HTCC1002
Length = 434
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +2
Query: 191 LKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPV 370
L ++ T +T +E D++ + FR D +T + K+ ++ +KA +L P
Sbjct: 219 LVNSWTTIPHVTNHDEADITEMEVFRTSLTDMYTGERK-KITPLAFIIKALVASLKKFPS 277
Query: 371 VNAVI---EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSEN 541
N+ I E +I + Y + +AV TP GL+VP IR+ N + + I S + N
Sbjct: 278 FNSSIDNIENGKITIKKYFHVGIAVDTPHGLMVPKIRSADNKSISYISNELKTVSDQCRN 337
>UniRef50_Q14PE3 Cluster: Hypothetical dihydrolipoamide
acetyltransferase protein; n=1; Spiroplasma citri|Rep:
Hypothetical dihydrolipoamide acetyltransferase protein
- Spiroplasma citri
Length = 582
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/144 (22%), Positives = 77/144 (53%), Gaps = 2/144 (1%)
Frame = +2
Query: 116 SKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTK 295
+KE + +VK+N+ A+ + +++ A E+D+S +++ + +++
Sbjct: 345 TKENTQSLQVDKVKLNQEAIIRAKEIMESKKNIAHSFIDVEVDVSELVSLLSIMREAYSQ 404
Query: 296 KHSIKLGLMSPFVKAAANALMDQPVVNA--VIEENEIIYRDYVDISVAVATPKGLVVPVI 469
+ IKL L+ + KA + L P++NA + +E I+ + + +I+ +V + + +PV+
Sbjct: 405 -NDIKLTLLPFYAKAVYDGLKKFPILNASFISQEKAILLKWFYNIAFSVDSDTAVKMPVL 463
Query: 470 RNVQNMTYADIRAHHSWASGKSEN 541
N++N++ +I + + GKS N
Sbjct: 464 YNLKNVSIKEIASKVTKLIGKSIN 487
>UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative; n=2;
Chlamydiales|Rep: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative - Chlamydia
muridarum
Length = 428
Score = 47.2 bits (107), Expect = 3e-04
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ I++RL+ A+ I S ++A K+ + +IKL + V+A A
Sbjct: 212 RESISKRLQAAKTFIPHFYVRQRIYASPLLALLKE-----LQVQNIKLSINDCIVRACAL 266
Query: 350 ALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
AL + P +N+ +N II +DIS+AVA P G++ P+IR I A
Sbjct: 267 ALKEFPEINSGFNSVDNTIIRFSTIDISIAVAIPDGVITPIIRCADRKNVGTISA 321
>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 399
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/116 (25%), Positives = 56/116 (48%)
Frame = +2
Query: 140 TEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGL 319
T +RV + ++ + R+ + A T E+D+S ++ R + K+ +
Sbjct: 175 TARRVPLTPTQRLVGSRMLQSLRETAQYTLGREVDISALIKVRME-----LKQKGSPANI 229
Query: 320 MSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
KA A+++ PV+ AVI+ ++++ V + AVA L+VPVI+N +
Sbjct: 230 TDLIHKAVVQAILENPVMQAVIDGDDMVVPAEVHLGFAVARGDELLVPVIKNAHRL 285
>UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=9;
Rickettsiales|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Wolbachia pipientis wMel
Length = 454
Score = 47.2 bits (107), Expect = 3e-04
Identities = 32/110 (29%), Positives = 63/110 (57%), Gaps = 2/110 (1%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDA-QNT-NAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
V+++ RQ IAQRL ++ QN + LT ++D + K +++ + + + + +
Sbjct: 227 VEVSNMRQVIAQRLTESKQNVPHFYLTVDCQVDK---LISLKNEINSADENNKVTINDL- 282
Query: 326 PFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRN 475
+KAAA ++ P +N+ +N+I+ +DIS+AVA GL+ P+++N
Sbjct: 283 -IIKAAAFSMKKFPDINSSWIDNKILRYSNIDISIAVALEDGLITPIVKN 331
>UniRef50_Q7SH25 Cluster: Putative uncharacterized protein
NCU02704.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU02704.1 - Neurospora crassa
Length = 562
Score = 47.2 bits (107), Expect = 3e-04
Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 13/160 (8%)
Frame = +2
Query: 68 AQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
A A AT I G + E V + R ++ + + + + L +E+D
Sbjct: 291 AAAAAAATAASAFSSPDATIPGPQKETPVPLTRTQEMMFKSMTRSLTIPHFLYA-DEVDF 349
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMS-----PFV-KAAANALMDQPVVNAVIE------- 388
+ ++ R + L+ K + G +S PF+ KA + AL PV+NA +E
Sbjct: 350 TPLVELRTR-LNRVLSKSGLPEGQVSKLSYLPFIIKAVSMALYKYPVLNARVELDSNSNG 408
Query: 389 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRA 508
+ ++ R +I VA+ TP GL+VPVI+NV ++ I A
Sbjct: 409 KPSLVMRSQHNIGVAMDTPSGLLVPVIKNVGSLNILSIAA 448
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 46.8 bits (106), Expect = 4e-04
Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +2
Query: 77 IETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHI 256
IE A + PP AG+ + + R+ IA+RL ++++T E M +
Sbjct: 138 IERA-LSAPPAAPVTAPAGSGDFTEIAHSNMRRTIARRLSESKSTIPHFYLTVECRMERL 196
Query: 257 MAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAV 436
+A R + ++ K+ + V+A A AL + P N E+ + D++VAV
Sbjct: 197 LALRAE-INAPNNASRRKISINDLIVRAVAVALREVPQANVGWTESAMRQYAQADVAVAV 255
Query: 437 ATPKGLVVPVIRNV--QNMTYADIRAHH 514
AT GL+ P++ V + + ++RA H
Sbjct: 256 ATDGGLITPIVAVVTGERGSTQELRAAH 283
>UniRef50_A4XHV3 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Caldicellulosiruptor
saccharolyticus DSM 8903|Rep: Catalytic domain of
components of various dehydrogenase complexes -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 460
Score = 46.4 bits (105), Expect = 5e-04
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 1/136 (0%)
Frame = +2
Query: 71 QAIETATVKVPPQDYSKEIAGTRTE-QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
+A E+ ++ + S +I TE + ++ R+ IA+ + + T A LT D
Sbjct: 207 KAKESFKIQKSDIEISAQIIKDETEYEEAPLSNIRKTIAKAMYLSLTTTAQLTLHTSFDA 266
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDIS 427
S+I+ FRK+ + K + + + A + L +NA ++++ Y V +
Sbjct: 267 SNILEFRKRVKENREKLGLEDITINDIILFAVSRVLPKHKALNAHFLDDKMRYFKNVHLG 326
Query: 428 VAVATPKGLVVPVIRN 475
AV T +GL+VP I N
Sbjct: 327 FAVDTERGLMVPTIFN 342
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 46.4 bits (105), Expect = 5e-04
Identities = 32/126 (25%), Positives = 63/126 (50%), Gaps = 7/126 (5%)
Frame = +2
Query: 146 QRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMS 325
+R+ + R+ A+ + ++ ++ F ++D S M F K+ L IK+ +
Sbjct: 295 ERIPVKGVRKATAKAMVESAFAAPHVSIFVDVDASRTMEFVKR-LKVSRDFEGIKVSPLL 353
Query: 326 PFVKAAANALMDQPVVNAVIEEN-------EIIYRDYVDISVAVATPKGLVVPVIRNVQN 484
KA A P VNA ++ EI + ++++ +A ATP+GL+VP I+N Q+
Sbjct: 354 ILAKAVIWAAARNPSVNATWVDSADGSDTAEIHVKHFMNLGIAAATPRGLMVPNIKNAQD 413
Query: 485 MTYADI 502
++ ++
Sbjct: 414 LSLKEL 419
>UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=6; Trypanosomatidae|Rep: Dihydrolipoamide
acetyltransferase, putative - Leishmania major
Length = 463
Score = 46.4 bits (105), Expect = 5e-04
Identities = 36/105 (34%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAM-LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAA 346
R IA+RL ++N F++ + +++A K+ L+ K+ + VKA A
Sbjct: 238 RSVIAKRLHQSKNLEIPHYYLFDDCRVDNMLALIKQ-LNA-KGNGEYKITVNDYIVKAVA 295
Query: 347 NALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQ 481
A P VN+ + + I VD+SVAVATP GL+ P+IRN Q
Sbjct: 296 RANTLVPEVNSSWQGDFIRQYATVDVSVAVATPTGLITPIIRNAQ 340
>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
Bacillus sp. NRRL B-14911
Length = 391
Score = 46.0 bits (104), Expect = 6e-04
Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R+ A+++ + + T F ++D++ + FR++ KK ++ + + ++KA +
Sbjct: 171 RKMTAEKMVQSLSLIPHCTHFEDVDVTELSVFREE-----LKKQEKQVTMTAFYIKALSM 225
Query: 350 ALMDQPVVNAVIEENEIIYRDYVD--ISVAVATPKGLVVPVIRNVQNMTYADI 502
AL PV N+ ++E + + I VAV GL+VPVI N + T A+I
Sbjct: 226 ALKRFPVFNSRLDEKAGLIHLLPEHHIGVAVNAEDGLIVPVIGNAEEKTIAEI 278
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 46.0 bits (104), Expect = 6e-04
Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH-SIKLGLMSPFVKAAA 346
R+ IA RL +++ T + ++ ++ R + + F K H ++KL + +KA A
Sbjct: 209 RKVIASRLTESKTTIPHFYVSIDCEVDNLNLLRAE-FNAFYKDHENVKLTVNDFIIKAVA 267
Query: 347 NALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRN 475
A+ P +N++ + +DISVAV+T GL+ P++ N
Sbjct: 268 LAIHKHPEINSMWLSEGVKKNKNIDISVAVSTDDGLMTPIVFN 310
>UniRef50_A1SQ65 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Nocardioides sp.
JS614|Rep: Catalytic domain of components of various
dehydrogenase complexes - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 427
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 1/140 (0%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
V +R R+ +A RL +++ T + ++ R + + ++ L
Sbjct: 207 VPHSRLRRAVANRLAESKQTAPHFYLRATVRADRLVDLRAE----LNEGAETRVSLNDLV 262
Query: 332 VKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAH 511
VKA A A P +N V + + VD++VAVAT +GLV PV+R+V ++T + A
Sbjct: 263 VKAVAAAHARVPEMNVVWTPDAVRSFSSVDVAVAVATDRGLVTPVLRDVTSLTVTAVAAK 322
Query: 512 -HSWASGKSENR*AHDRKNG 568
A+ E R D G
Sbjct: 323 VQDLAARAREGRLKQDELEG 342
>UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, component
X; n=2; Dictyostelium discoideum|Rep: Pyruvate
dehydrogenase complex, component X - Dictyostelium
discoideum AX4
Length = 413
Score = 46.0 bits (104), Expect = 6e-04
Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 161 NRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKA 340
N R+ IA +L ++ E ++ +++A RK + ++K+ + ++A
Sbjct: 135 NNIRRVIATKLSQSKQQVPHFYMTVECELDNVLAMRK------SMPENVKISVNDFVLRA 188
Query: 341 AANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRN 475
A AL D P N+ E E I VDIS AV+T +GL+ P+I N
Sbjct: 189 CALALRDNPQANSKWSDEHGEAILNPTVDISFAVSTDRGLITPIITN 235
>UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1;
Azoarcus sp. BH72|Rep: Putative uncharacterized protein
- Azoarcus sp. (strain BH72)
Length = 237
Score = 45.6 bits (103), Expect = 8e-04
Identities = 26/67 (38%), Positives = 37/67 (55%)
Frame = +2
Query: 308 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 487
KL + + + A A AL P +NA++ E E+ D ++I VAVA GL+VPVIR
Sbjct: 67 KLSVNAFVLHAVAQALRAHPRLNALMREKEVELVDDINIGVAVALDDGLMVPVIRQADTK 126
Query: 488 TYADIRA 508
A + A
Sbjct: 127 PVAALAA 133
>UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 421
Score = 45.6 bits (103), Expect = 8e-04
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Frame = +2
Query: 182 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRK---KHLDTFTKKHSIKLGLMSPFVKAAANA 352
A+RL +++ ++ + ++M R+ K L K+ + VKA+A A
Sbjct: 203 AERLTESKQQLPHFYLTVDVRLDNMMGIRETLNKQLADDKAAEGAKISVNDFIVKASAKA 262
Query: 353 LMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGK 532
L+ P VNA ++I DISVAV T +GL+VP++R+ + I A +G+
Sbjct: 263 LLAVPDVNASWLGDKIRKYKKADISVAVQTERGLMVPIVRSACCLGLKSISAEVKSLAGR 322
Query: 533 SEN 541
+ +
Sbjct: 323 ARS 325
>UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2)
component of 2-oxoacid dehydrogenase complexes; n=1;
Burkholderia xenovorans LB400|Rep: Dihydrolipoamide
acyltransferase (E2) component of 2-oxoacid
dehydrogenase complexes - Burkholderia xenovorans
(strain LB400)
Length = 428
Score = 45.2 bits (102), Expect = 0.001
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 1/121 (0%)
Frame = +2
Query: 179 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN-AL 355
IA+RL ++ T E ++S + R + D + + ++ FV AA AL
Sbjct: 214 IARRLVTSKQTIPHFYLSVEAEISAVQRLRSQLNDAQSNRRFT----VNHFVVAAVGRAL 269
Query: 356 MDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKS 535
P N V +++ I D+ VAV T +GL+VPV+R+V ++ H S A G++
Sbjct: 270 ALVPEANRVWDDSGITSFAATDVGVAVHTERGLLVPVLRDVGRQALGEVARHASEAIGRA 329
Query: 536 E 538
+
Sbjct: 330 Q 330
>UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Shewanella frigidimarina NCIMB
400|Rep: Dihydrolipoyllysine-residue succinyltransferase
- Shewanella frigidimarina (strain NCIMB 400)
Length = 252
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/120 (28%), Positives = 60/120 (50%), Gaps = 9/120 (7%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK-----HLDTF--TKKHSIKLGLMSP 328
R+ IA + ++ +T +E+D+ I A R K D T++ I L+
Sbjct: 26 RRIIANNVLESWTHIPHVTHHDEVDIGAIEALRHKLNIEHSADVLGVTEEAQIHFTLLPF 85
Query: 329 FVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+KA AL P NA + ++ ++ + Y ++ +AV T GL+VPVI+NV +T ++
Sbjct: 86 ILKATIEALKLFPAFNASLSDDGETLMLKHYYNLGIAVDTSNGLLVPVIKNVDALTLEEL 145
>UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid
dehydrogenase E2 subunit; n=9; Magnoliophyta|Rep:
Branched chain alpha-keto acid dehydrogenase E2 subunit
- Arabidopsis thaliana (Mouse-ear cress)
Length = 483
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Frame = +2
Query: 302 SIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRN 475
+IK + +K+ + AL P VN+ E EII + +I VA+AT GLVVP I+N
Sbjct: 303 TIKHTFLPTLIKSLSMALTKYPFVNSCFNAESLEIILKGSHNIGVAMATEHGLVVPNIKN 362
Query: 476 VQNMTYADI 502
VQ+++ +I
Sbjct: 363 VQSLSLLEI 371
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/107 (27%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Frame = +2
Query: 152 VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF 331
+++ ++ A+RL +A+ T + E ++ ++ R + K S K+ +
Sbjct: 258 IELTNYKRVTAERLTEAKQTVPLFYVSVECEVDKLLTLRSQ----LNKIASTKISINDML 313
Query: 332 VKAAANALMDQPVVNAVIEENEII-YRDYVDISVAVATPKGLVVPVI 469
+KA + A + PV N+ + + Y+D VD+SVAV TP GL+ P++
Sbjct: 314 IKACSLACLKVPVTNSSWMGDFVRRYKD-VDMSVAVQTPNGLITPIV 359
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Frame = +2
Query: 158 MNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVK 337
++R R+ IA+ + +++ + E+D+ +MA R++ + T+ + + VK
Sbjct: 213 LSRMRKAIARAMNESKPGVPHIYLTIEVDVDALMALREQIAASGTR-----VSVNDLVVK 267
Query: 338 AAANALMDQPVVNAVIEENE-----IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
AAA AL P +N + I+ ++I VAVA GLV PV+R+ + + I
Sbjct: 268 AAAKALAKVPAINVSFSQTADGQPGIVRHSQINIGVAVALDDGLVAPVVRDADKKSVSTI 327
Query: 503 RA 508
A
Sbjct: 328 SA 329
>UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 490
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/96 (27%), Positives = 54/96 (56%), Gaps = 6/96 (6%)
Frame = +2
Query: 233 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN------ 394
+ +D S++ + RKK+ ++ + ++ + +KA + P++N+ ++
Sbjct: 285 DSVDFSNLTSMRKKY--NAGREKTDRITPLPVIIKAISLTFQQFPLLNSHLDTTSNPNKP 342
Query: 395 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADI 502
+I+ + +I VAV +P GL+VPVI+NVQN + A +
Sbjct: 343 QIVLKGSHNIGVAVDSPSGLLVPVIKNVQNHSIASL 378
>UniRef50_Q6XYS6 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Spiroplasma kunkelii|Rep: Dihydrolipoamide
acetyltransferase - Spiroplasma kunkelii
Length = 617
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/143 (22%), Positives = 77/143 (53%), Gaps = 2/143 (1%)
Frame = +2
Query: 119 KEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKK 298
KE T ++K+N+ A+ + +++ E+D+S +++ + +++
Sbjct: 381 KENPQTLQVDKIKLNQEAIIRAKEIMESKKNIVNGFIDVEVDVSELVSLLLIMREAYSQ- 439
Query: 299 HSIKLGLMSPFVKAAANALMDQPVVNA--VIEENEIIYRDYVDISVAVATPKGLVVPVIR 472
+ I+L L+ +VKA + L PV+NA + ++N+I+ + + +I+ +V + + +PV+
Sbjct: 440 NDIELTLLPFYVKAVYDGLKKFPVLNASFISQKNKILLKWFYNIAFSVDSYTAVKMPVLY 499
Query: 473 NVQNMTYADIRAHHSWASGKSEN 541
N++N++ +I + + KS N
Sbjct: 500 NLKNVSIKEIASKVTKLISKSIN 522
>UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2;
Sulfitobacter|Rep: Acetoin dehydrogenase E2 component -
Sulfitobacter sp. NAS-14.1
Length = 223
Score = 43.6 bits (98), Expect = 0.003
Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R IA + + T A LT D + +MA K L K S++ LM V+A
Sbjct: 11 RGMIADAMTKSLATAAQLTHHGSADATALMA-EKTRLGAAGTKISVEDLLMLAVVRA--- 66
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVV-PVIRNVQNMTYADIRA 508
L P N +E E+ D VD+SVA+A P L+V P + M ++RA
Sbjct: 67 -LKKNPDANGRVEGREVHLSDAVDLSVAIALPGNLLVAPAMFGADAMDVTELRA 119
>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_3,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 628
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/102 (29%), Positives = 48/102 (47%)
Frame = +2
Query: 170 RQRIAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 349
R IA RL +++ T + M ++ R++ K +K+ + +KA+A
Sbjct: 413 RLTIAARLLESKTTIPHYYLTMTVTMDKVLKVREE----LNKLQKVKISVNDFIIKASAL 468
Query: 350 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRN 475
AL D P N+ I DIS+AVAT GL+ P++ N
Sbjct: 469 ALKDVPQANSQWHGTYIRKFANADISIAVATDAGLITPIVFN 510
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 43.2 bits (97), Expect = 0.004
Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 2/132 (1%)
Frame = +2
Query: 86 ATVKVPPQDYSKEIA-GTRTEQR-VKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDMSHIM 259
A K P+ ++ A G+R + + ++ R+ IAQR+ + + +++M M
Sbjct: 290 AAAKKAPEAAARPAAPGSRPAPKTLPISTMRKVIAQRMSEVKPGVPHFYLTVDVEMDAAM 349
Query: 260 AFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVA 439
R++ K K+ + VKA A AL P +N ++ N I+ D+ +AVA
Sbjct: 350 KIREE-----AKALESKVSVNDIVVKAVAVALRRSPKMNVSLQGNTILQFATADVGIAVA 404
Query: 440 TPKGLVVPVIRN 475
GL+ P+I++
Sbjct: 405 IEDGLITPIIKD 416
>UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1;
marine actinobacterium PHSC20C1|Rep: Dihydrolipoamide
acetyltransferase - marine actinobacterium PHSC20C1
Length = 425
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/158 (22%), Positives = 68/158 (43%)
Frame = +2
Query: 68 AQAIETATVKVPPQDYSKEIAGTRTEQRVKMNRGRQRIAQRLKDAQNTNAMLTTFNEIDM 247
A A +A V P + A + R R+++A ++ A T + ++D+
Sbjct: 182 APAAPSAPVAAPAAAQAPTPAKVVDPVEARRLRTRKQVA-KVMSASALVPQFTAYVDLDL 240
Query: 248 SHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDIS 427
S + A RK L + + V+A A AL + +N + + +++ I+
Sbjct: 241 SALAAVRKTTLGGAS--------WTALLVRAQAIALAENAALNGTWTDEGVAANEHIGIA 292
Query: 428 VAVATPKGLVVPVIRNVQNMTYADIRAHHSWASGKSEN 541
+A+ P GL+ PV+ N T AD+ A + ++ N
Sbjct: 293 LAIDAPSGLIAPVLTNSHEGTLADLVAEIATVVDETRN 330
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 550,131,891
Number of Sequences: 1657284
Number of extensions: 10923593
Number of successful extensions: 39812
Number of sequences better than 10.0: 353
Number of HSP's better than 10.0 without gapping: 37439
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39616
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 38738010471
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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