Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-0349
(769 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 263 6e-70
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 263 6e-70
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 263 6e-70
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 263 6e-70
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 263 6e-70
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 253 6e-67
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 253 6e-67
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 253 6e-67
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 253 6e-67
AL359195-3|CAI13696.1| 145|Homo sapiens methionine adenosyltran... 103 5e-22
AF260332-1|AAG44663.1| 280|Homo sapiens DC33 protein. 31 6.0
BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, mem... 30 7.9
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 263 bits (644), Expect = 6e-70
Identities = 123/156 (78%), Positives = 141/156 (90%), Gaps = 1/156 (0%)
Frame = +2
Query: 80 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 256
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 257 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 436
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 437 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLT 544
A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLT 153
Score = 57.6 bits (133), Expect = 5e-08
Identities = 26/36 (72%), Positives = 29/36 (80%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNM 653
+VLAHKLN K+AELRRNG W RPDSKTQVT+ M
Sbjct: 154 IVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 263 bits (644), Expect = 6e-70
Identities = 123/156 (78%), Positives = 141/156 (90%), Gaps = 1/156 (0%)
Frame = +2
Query: 80 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 256
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 257 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 436
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 437 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLT 544
A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLT 153
Score = 57.6 bits (133), Expect = 5e-08
Identities = 26/36 (72%), Positives = 29/36 (80%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNM 653
+VLAHKLN K+AELRRNG W RPDSKTQVT+ M
Sbjct: 154 IVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 263 bits (644), Expect = 6e-70
Identities = 123/156 (78%), Positives = 141/156 (90%), Gaps = 1/156 (0%)
Frame = +2
Query: 80 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 256
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 257 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 436
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 437 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLT 544
A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLT 153
Score = 57.6 bits (133), Expect = 5e-08
Identities = 26/36 (72%), Positives = 29/36 (80%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNM 653
+VLAHKLN K+AELRRNG W RPDSKTQVT+ M
Sbjct: 154 IVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 263 bits (644), Expect = 6e-70
Identities = 123/156 (78%), Positives = 141/156 (90%), Gaps = 1/156 (0%)
Frame = +2
Query: 80 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 256
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 257 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 436
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 437 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLT 544
A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLT 153
Score = 57.6 bits (133), Expect = 5e-08
Identities = 26/36 (72%), Positives = 29/36 (80%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNM 653
+VLAHKLN K+AELRRNG W RPDSKTQVT+ M
Sbjct: 154 IVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 263 bits (644), Expect = 6e-70
Identities = 123/156 (78%), Positives = 141/156 (90%), Gaps = 1/156 (0%)
Frame = +2
Query: 80 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 256
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 257 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 436
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 437 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLT 544
A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLT 153
Score = 57.6 bits (133), Expect = 5e-08
Identities = 26/36 (72%), Positives = 29/36 (80%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNM 653
+VLAHKLN K+AELRRNG W RPDSKTQVT+ M
Sbjct: 154 IVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 253 bits (619), Expect = 6e-67
Identities = 113/144 (78%), Positives = 134/144 (93%)
Frame = +2
Query: 113 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 292
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 293 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 472
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 473 VGAGDQGLMFGYATDETEECMPLT 544
VGAGDQGLMFGYATDETEECMPLT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLT 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNMYLLGGATVP 680
++LAHKLN ++A+LRR+G W RPDSKTQVT+ M GA +P
Sbjct: 154 IILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQ-DNGAVIP 197
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 253 bits (619), Expect = 6e-67
Identities = 113/144 (78%), Positives = 134/144 (93%)
Frame = +2
Query: 113 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 292
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 293 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 472
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 473 VGAGDQGLMFGYATDETEECMPLT 544
VGAGDQGLMFGYATDETEECMPLT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLT 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNMYLLGGATVP 680
++LAHKLN ++A+LRR+G W RPDSKTQVT+ M GA +P
Sbjct: 154 IILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQ-DNGAVIP 197
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 253 bits (619), Expect = 6e-67
Identities = 113/144 (78%), Positives = 134/144 (93%)
Frame = +2
Query: 113 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 292
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 293 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 472
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 473 VGAGDQGLMFGYATDETEECMPLT 544
VGAGDQGLMFGYATDETEECMPLT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLT 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNMYLLGGATVP 680
++LAHKLN ++A+LRR+G W RPDSKTQVT+ M GA +P
Sbjct: 154 IILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQ-DNGAVIP 197
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 253 bits (619), Expect = 6e-67
Identities = 113/144 (78%), Positives = 134/144 (93%)
Frame = +2
Query: 113 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 292
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 293 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 472
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 473 VGAGDQGLMFGYATDETEECMPLT 544
VGAGDQGLMFGYATDETEECMPLT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLT 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNMYLLGGATVP 680
++LAHKLN ++A+LRR+G W RPDSKTQVT+ M GA +P
Sbjct: 154 IILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQ-DNGAVIP 197
>AL359195-3|CAI13696.1| 145|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 145
Score = 103 bits (248), Expect = 5e-22
Identities = 47/68 (69%), Positives = 59/68 (86%), Gaps = 3/68 (4%)
Frame = +2
Query: 350 HIGYDDSSK---GFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFGYATDE 520
H+ D ++K GFD+KTC+V++AL+QQSP+IA VH +RN+E+VGAGDQGLMFGYATDE
Sbjct: 23 HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDE 82
Query: 521 TEECMPLT 544
TEECMPLT
Sbjct: 83 TEECMPLT 90
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/81 (51%), Positives = 49/81 (60%)
Frame = +2
Query: 152 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKV 331
ESVGEGHPDK+CDQISDA+LDAHL QDP+AKVAC KT VL+ E S +
Sbjct: 1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHL 60
Query: 332 VRETVKHIGYDDSSKGFDYKT 394
R + +G D F Y T
Sbjct: 61 DRNE-EDVGAGDQGLMFGYAT 80
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +3
Query: 546 VVLAHKLNQKIAELRRNGEFWWARPDSKTQVTLPNMYLLGGATVP 680
++LAHKLN ++A+LRR+G W RPDSKTQVT+ M GA +P
Sbjct: 91 IILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQ-DNGAVIP 134
>AF260332-1|AAG44663.1| 280|Homo sapiens DC33 protein.
Length = 280
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/55 (23%), Positives = 21/55 (38%)
Frame = +2
Query: 458 RNDEEVGAGDQGLMFGYATDETEECMPLTRSACTQTQSENCRAQAKWRILVGKTR 622
+N D ++ T C P +SAC + + R+ A W + TR
Sbjct: 141 KNRTRTTPADSSALYPATTTSPSRCCPSGKSACPSSPPQGARSDAPWASVTPPTR 195
>BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, member
15 protein.
Length = 691
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/66 (30%), Positives = 31/66 (46%)
Frame = +2
Query: 41 WANSKFRMPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAH 220
W K + P T+ M G++K + +D GS S + P +M D +SDAI
Sbjct: 235 WKKIK-KDPYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLK 288
Query: 221 LNQDPD 238
+NQ +
Sbjct: 289 INQQEE 294
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,535,545
Number of Sequences: 237096
Number of extensions: 2997522
Number of successful extensions: 9484
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 9223
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9484
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9255747988
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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