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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ceN-0309
         (681 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

DQ118293-1|AAZ99029.1| 2391|Homo sapiens filaggrin 2 protein.          38   0.033
AY827490-1|AAX12417.1| 2391|Homo sapiens ifapsoriasin protein.         38   0.033
AL356504-2|CAC13173.2| 2391|Homo sapiens filaggrin 2 protein.          38   0.033
AY396741-1|AAR91619.1| 2850|Homo sapiens hornerin precursor prot...    31   3.8  
AL589986-3|CAH70026.1| 2850|Homo sapiens hornerin protein.             31   3.8  
BC023660-1|AAH23660.1|  410|Homo sapiens epithelial stromal inte...    31   5.0  
AL445217-1|CAM17275.1|  410|Homo sapiens epithelial stromal inte...    31   5.0  
AL137878-1|CAM13100.1|  410|Homo sapiens epithelial stromal inte...    31   5.0  
U41060-1|AAA96258.2|  749|Homo sapiens estrogen regulated LIV-1 ...    30   6.6  
AB104446-1|BAC57496.1|  493|Homo sapiens hornerin protein.             30   6.6  

>DQ118293-1|AAZ99029.1| 2391|Homo sapiens filaggrin 2 protein.
          Length = 2391

 Score = 37.9 bits (84), Expect = 0.033
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621 YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGTS 487
           +  H + S  +SG G   SRSH+ +     SG S+S  + QHGS++G TS
Sbjct: 820 FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869



 Score = 34.7 bits (76), Expect = 0.31
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGT 490
            +  H   S   SG G   SRSH+ +     SG S+S  + QHGS++G T
Sbjct: 897  FGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQT 945



 Score = 34.7 bits (76), Expect = 0.31
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGTS 487
            +  H   S  +SG G   SRS + +     SG S+S  + QHGS +G TS
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTS 1100



 Score = 33.5 bits (73), Expect = 0.71
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRD-----ASGRSRSVDFDQHGSTAGGTS 487
            +  H++ S  +SG G   SRS +       SG S+S  + QHGS++G T+
Sbjct: 974  FGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTT 1023


>AY827490-1|AAX12417.1| 2391|Homo sapiens ifapsoriasin protein.
          Length = 2391

 Score = 37.9 bits (84), Expect = 0.033
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621 YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGTS 487
           +  H + S  +SG G   SRSH+ +     SG S+S  + QHGS++G TS
Sbjct: 820 FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869



 Score = 34.7 bits (76), Expect = 0.31
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGT 490
            +  H   S   SG G   SRSH+ +     SG S+S  + QHGS++G T
Sbjct: 897  FGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQT 945



 Score = 34.7 bits (76), Expect = 0.31
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGTS 487
            +  H   S  +SG G   SRS + +     SG S+S  + QHGS +G TS
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTS 1100



 Score = 33.5 bits (73), Expect = 0.71
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRD-----ASGRSRSVDFDQHGSTAGGTS 487
            +  H++ S  +SG G   SRS +       SG S+S  + QHGS++G T+
Sbjct: 974  FGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTT 1023


>AL356504-2|CAC13173.2| 2391|Homo sapiens filaggrin 2 protein.
          Length = 2391

 Score = 37.9 bits (84), Expect = 0.033
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621 YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGTS 487
           +  H + S  +SG G   SRSH+ +     SG S+S  + QHGS++G TS
Sbjct: 820 FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869



 Score = 34.7 bits (76), Expect = 0.31
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGT 490
            +  H   S   SG G   SRSH+ +     SG S+S  + QHGS++G T
Sbjct: 897  FGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQT 945



 Score = 34.7 bits (76), Expect = 0.31
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDA-----SGRSRSVDFDQHGSTAGGTS 487
            +  H   S  +SG G   SRS + +     SG S+S  + QHGS +G TS
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTS 1100



 Score = 33.5 bits (73), Expect = 0.71
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 5/50 (10%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRD-----ASGRSRSVDFDQHGSTAGGTS 487
            +  H++ S  +SG G   SRS +       SG S+S  + QHGS++G T+
Sbjct: 974  FGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTT 1023


>AY396741-1|AAR91619.1| 2850|Homo sapiens hornerin precursor
           protein.
          Length = 2850

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
 Frame = -1

Query: 621 YDDHDNHSAHNSGIGNITSRS--------HRDASGRSRSVDFDQHGSTAG---GTSKRRR 475
           Y  H + S H+SG G   SRS        HR +SG S S  + QHGS +    G  ++  
Sbjct: 244 YSQHGSGSGHSSGYGQHGSRSGQSSRGDRHRSSSGSSSS--YGQHGSGSRQSLGHGRQGS 301

Query: 474 ENRYSISE*REG 439
            +R S S  R G
Sbjct: 302 GSRQSPSHVRHG 313



 Score = 31.1 bits (67), Expect = 3.8
 Identities = 16/46 (34%), Positives = 26/46 (56%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTSK 484
            Y  H + S H+SG G   SRS + + G       ++HGS++G +S+
Sbjct: 2120 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSSR 2158



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
 Frame = -1

Query: 594  HNSGIGNITSRSHRDASGRSRSVDFDQHGSTAG-GTSKRRRENRYSISE*REGRAQDSFA 418
            H SG G  +   H+ +SG+S    + QHGS +G  +S  +  +R   S   E     S +
Sbjct: 922  HGSGSGQSSGFGHKSSSGQSSG--YTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979

Query: 417  LVS*GDAVRGSVPPHGRAQ 361
              S G    GS    G  Q
Sbjct: 980  SSSYGQHGSGSRQSLGHGQ 998



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTS 487
            Y  H + S H+SG G   SRS + + G       ++HGS++G +S
Sbjct: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSS 1217



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGR-----SRSVD-FDQHGSTAGGTSKRRRENRYS 460
            Y  H + S H+SG G   SRS + + G      SRS   + QHGS +  +S   R+   S
Sbjct: 1650 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGS 1709

Query: 459  ISE*REGR 436
                  GR
Sbjct: 1710 GQSPSRGR 1717



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTS 487
            Y  H + S H+SG G   SRS + + G       ++HGS++G +S
Sbjct: 2590 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSS 2627



 Score = 29.9 bits (64), Expect = 8.8
 Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 6/48 (12%)
 Frame = -1

Query: 612  HDNHSAHNSGIGNITSRSHRDA------SGRSRSVDFDQHGSTAGGTS 487
            +++ S+H+SG+G+  SRS + +      S    S    QHGST+G +S
Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1557


>AL589986-3|CAH70026.1| 2850|Homo sapiens hornerin protein.
          Length = 2850

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
 Frame = -1

Query: 621 YDDHDNHSAHNSGIGNITSRS--------HRDASGRSRSVDFDQHGSTAG---GTSKRRR 475
           Y  H + S H+SG G   SRS        HR +SG S S  + QHGS +    G  ++  
Sbjct: 244 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS--YGQHGSGSRQSLGHGRQGS 301

Query: 474 ENRYSISE*REG 439
            +R S S  R G
Sbjct: 302 GSRQSPSHVRHG 313



 Score = 31.1 bits (67), Expect = 3.8
 Identities = 16/46 (34%), Positives = 26/46 (56%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTSK 484
            Y  H + S H+SG G   SRS + + G       ++HGS++G +S+
Sbjct: 2120 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSSR 2158



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
 Frame = -1

Query: 594  HNSGIGNITSRSHRDASGRSRSVDFDQHGSTAG-GTSKRRRENRYSISE*REGRAQDSFA 418
            H SG G  +   H+ +SG+S    + QHGS +G  +S  +  +R   S   E     S +
Sbjct: 922  HGSGSGQSSGFGHKSSSGQSSG--YTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979

Query: 417  LVS*GDAVRGSVPPHGRAQ 361
              S G    GS    G  Q
Sbjct: 980  SSSYGQHGSGSRQSLGHGQ 998



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTS 487
            Y  H + S H+SG G   SRS + + G       ++HGS++G +S
Sbjct: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSS 1217



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGR-----SRSVD-FDQHGSTAGGTSKRRRENRYS 460
            Y  H + S H+SG G   SRS + + G      SRS   + QHGS +  +S   R+   S
Sbjct: 1650 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGS 1709

Query: 459  ISE*REGR 436
                  GR
Sbjct: 1710 GQSPSRGR 1717



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 621  YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTS 487
            Y  H + S H+SG G   SRS + + G       ++HGS++G +S
Sbjct: 2590 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSS 2627



 Score = 29.9 bits (64), Expect = 8.8
 Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 6/48 (12%)
 Frame = -1

Query: 612  HDNHSAHNSGIGNITSRSHRDA------SGRSRSVDFDQHGSTAGGTS 487
            +++ S+H+SG+G+  SRS + +      S    S    QHGST+G +S
Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1557


>BC023660-1|AAH23660.1|  410|Homo sapiens epithelial stromal
           interaction 1 (breast) protein.
          Length = 410

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = +2

Query: 470 FSRRRFEVPPAVEPCWSKSTDLERPEASLWERLVIFPI 583
           FSR        + P W  STDLE+P   L+  +++F +
Sbjct: 322 FSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSL 359


>AL445217-1|CAM17275.1|  410|Homo sapiens epithelial stromal
           interaction 1 (breast) protein.
          Length = 410

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = +2

Query: 470 FSRRRFEVPPAVEPCWSKSTDLERPEASLWERLVIFPI 583
           FSR        + P W  STDLE+P   L+  +++F +
Sbjct: 322 FSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSL 359


>AL137878-1|CAM13100.1|  410|Homo sapiens epithelial stromal
           interaction 1 (breast) protein.
          Length = 410

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = +2

Query: 470 FSRRRFEVPPAVEPCWSKSTDLERPEASLWERLVIFPI 583
           FSR        + P W  STDLE+P   L+  +++F +
Sbjct: 322 FSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSL 359


>U41060-1|AAA96258.2|  749|Homo sapiens estrogen regulated LIV-1
           protein protein.
          Length = 749

 Score = 30.3 bits (65), Expect = 6.6
 Identities = 15/50 (30%), Positives = 21/50 (42%)
 Frame = -1

Query: 627 HLYDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTSKRR 478
           H++ DHD+HS H     +     H D    S       H   A G +KR+
Sbjct: 91  HIHHDHDHHSDHEH---HSDHERHSDHEHHSDHEHHSDHNHAASGKNKRK 137


>AB104446-1|BAC57496.1|  493|Homo sapiens hornerin protein.
          Length = 493

 Score = 30.3 bits (65), Expect = 6.6
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 621 YDDHDNHSAHNSGIGNITSRSHRDASGRSRSVDFDQHGSTAGGTS 487
           Y  H + S H+SG G   SRS + + G       ++HGS++G +S
Sbjct: 233 YSQHGSGSGHSSGYGQHGSRSGQSSRG-------ERHGSSSGSSS 270


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,309,146
Number of Sequences: 237096
Number of extensions: 1856325
Number of successful extensions: 4714
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4369
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4643
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7727256732
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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