Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ceN-0307
(651 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL590005-3|CAI14988.1| 5457|Homo sapiens dystonin protein. 225 1e-58
AL590005-2|CAI14989.1| 7543|Homo sapiens dystonin protein. 225 1e-58
AL512448-3|CAI16610.1| 5144|Homo sapiens dystonin protein. 225 1e-58
AL512448-2|CAI16608.1| 5457|Homo sapiens dystonin protein. 225 1e-58
AL512448-1|CAI16609.1| 7543|Homo sapiens dystonin protein. 225 1e-58
AL512422-3|CAI14342.1| 5457|Homo sapiens dystonin protein. 225 1e-58
AL512422-2|CAI14341.1| 7543|Homo sapiens dystonin protein. 225 1e-58
AL137008-4|CAI20332.1| 5144|Homo sapiens dystonin protein. 225 1e-58
AL137008-3|CAI20331.1| 5457|Homo sapiens dystonin protein. 225 1e-58
AL137008-2|CAI20330.1| 7543|Homo sapiens dystonin protein. 225 1e-58
AL096710-4|CAI22045.1| 5144|Homo sapiens dystonin protein. 225 1e-58
AL096710-3|CAI22043.1| 5457|Homo sapiens dystonin protein. 225 1e-58
AL096710-2|CAI22044.1| 7543|Homo sapiens dystonin protein. 225 1e-58
AF400226-1|AAL62061.1| 5171|Homo sapiens bullous pemphigoid anti... 225 1e-58
AB018271-1|BAA34448.2| 1637|Homo sapiens KIAA0728 protein protein. 225 1e-58
AL442071-4|CAH73671.1| 5938|Homo sapiens microtubule-actin cross... 223 4e-58
AL442071-2|CAH73669.1| 4433|Homo sapiens microtubule-actin cross... 223 4e-58
AL442071-1|CAH73668.1| 5430|Homo sapiens microtubule-actin cross... 223 4e-58
AL365277-12|CAI16422.1| 5938|Homo sapiens microtubule-actin cros... 223 4e-58
AL365277-10|CAI16420.1| 4433|Homo sapiens microtubule-actin cros... 223 4e-58
AL365277-7|CAI16417.1| 5430|Homo sapiens microtubule-actin cross... 223 4e-58
AL355477-1|CAH70156.1| 5430|Homo sapiens microtubule-actin cross... 223 4e-58
AL137853-3|CAI21816.1| 5938|Homo sapiens microtubule-actin cross... 223 4e-58
AL137853-2|CAI21815.1| 4433|Homo sapiens microtubule-actin cross... 223 4e-58
AL137853-1|CAI21814.1| 5430|Homo sapiens microtubule-actin cross... 223 4e-58
AB029290-1|BAA83821.1| 5430|Homo sapiens actin binding protein A... 223 4e-58
AB007934-1|BAA32310.3| 4433|Homo sapiens KIAA0465 protein protein. 223 4e-58
AF325341-2|AAL38997.1| 5314|Homo sapiens macrophin 1 isoform 4 p... 223 6e-58
AF325341-1|AAL39000.1| 4631|Homo sapiens macrophin 1 isoform 2 p... 223 6e-58
AF317696-1|AAL09459.1| 5938|Homo sapiens macrophin 1 isoform 4 p... 223 6e-58
AF141968-1|AAF06360.1| 5373|Homo sapiens trabeculin-alpha protein. 223 6e-58
AK025142-1|BAB15077.1| 167|Homo sapiens protein ( Homo sapiens ... 155 1e-37
AK055189-1|BAB70870.1| 1174|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AK096713-1|BAC04848.1| 990|Homo sapiens protein ( Homo sapiens ... 69 1e-11
X69086-1|CAA48829.1| 3433|Homo sapiens utrophin (dystrophin rela... 66 8e-11
AL590704-1|CAI10894.1| 3433|Homo sapiens utrophin protein. 66 8e-11
AL590488-1|CAI16497.1| 3433|Homo sapiens utrophin protein. 66 8e-11
AL513475-1|CAI13032.1| 3433|Homo sapiens utrophin protein. 66 8e-11
AL513184-1|CAI40502.1| 3433|Homo sapiens utrophin protein. 66 8e-11
AL357149-1|CAI40388.1| 3433|Homo sapiens utrophin protein. 66 8e-11
AL024474-2|CAI23353.1| 3433|Homo sapiens utrophin protein. 66 8e-11
BX537837-1|CAD97849.1| 1523|Homo sapiens hypothetical protein pr... 66 1e-10
BC090927-1|AAH90927.1| 997|Homo sapiens SYNE1 protein protein. 66 1e-10
AY184206-1|AAO27774.1| 3212|Homo sapiens nesprin-1 beta 2 protein. 66 1e-10
AY184203-1|AAO27771.1| 977|Homo sapiens nesprin-1 alpha 2 protein. 66 1e-10
AY061756-1|AAL33799.1| 982|Homo sapiens nesprin-1 alpha protein. 66 1e-10
AY061755-1|AAL33798.1| 3321|Homo sapiens nesprin-1 beta protein. 66 1e-10
AL450401-4|CAI40730.1| 2963|Homo sapiens spectrin repeat contain... 66 1e-10
AL450401-3|CAI40729.1| 3321|Homo sapiens spectrin repeat contain... 66 1e-10
AL450401-2|CAI40728.1| 982|Homo sapiens spectrin repeat contain... 66 1e-10
AL450401-1|CAI40727.1| 952|Homo sapiens spectrin repeat contain... 66 1e-10
AL357081-1|CAI41322.1| 3321|Homo sapiens spectrin repeat contain... 66 1e-10
AL138832-5|CAI42787.1| 2963|Homo sapiens spectrin repeat contain... 66 1e-10
AL138832-4|CAI42786.1| 3321|Homo sapiens spectrin repeat contain... 66 1e-10
AL138832-3|CAI42785.1| 982|Homo sapiens spectrin repeat contain... 66 1e-10
AL138832-2|CAI42784.1| 952|Homo sapiens spectrin repeat contain... 66 1e-10
AL078582-5|CAI42287.1| 2963|Homo sapiens spectrin repeat contain... 66 1e-10
AL078582-3|CAI42284.1| 3321|Homo sapiens spectrin repeat contain... 66 1e-10
AL078582-2|CAI42283.1| 982|Homo sapiens spectrin repeat contain... 66 1e-10
AL078582-1|CAI42282.1| 952|Homo sapiens spectrin repeat contain... 66 1e-10
AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein. 66 1e-10
AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein. 66 1e-10
AF444779-1|AAL38031.1| 1139|Homo sapiens myocyte inner nuclear m... 66 1e-10
AB018339-1|BAA34516.2| 1876|Homo sapiens KIAA0796 protein protein. 66 1e-10
AF043290-1|AAC02992.1| 374|Homo sapiens lymphocyte membrane ass... 58 2e-08
U83867-1|AAB41498.1| 2477|Homo sapiens alpha II spectrin protein. 56 1e-07
BC053521-1|AAH53521.1| 2452|Homo sapiens SPTAN1 protein protein. 56 1e-07
AL356481-4|CAH71405.1| 2472|Homo sapiens spectrin, alpha, non-er... 56 1e-07
AL356481-3|CAH71404.1| 2477|Homo sapiens spectrin, alpha, non-er... 56 1e-07
AB209860-1|BAD93097.1| 2506|Homo sapiens spectrin, alpha, non-er... 56 1e-07
AB191262-1|BAD52438.1| 2452|Homo sapiens non-erythrocytic spectr... 56 1e-07
J05243-1|AAA51790.1| 2472|Homo sapiens SPTAN1 protein. 54 4e-07
AY061759-1|AAL33802.1| 3270|Homo sapiens nesprin-2 gamma protein. 53 8e-07
AF495911-1|AAN60443.1| 6884|Homo sapiens nesprin-2 protein. 53 8e-07
AF435011-1|AAL33548.1| 6885|Homo sapiens NUANCE protein. 53 8e-07
AB023228-1|BAA76855.3| 3541|Homo sapiens KIAA1011 protein protein. 53 8e-07
X14298-1|CAA32479.1| 3685|Homo sapiens protein ( Human mRNA for ... 53 1e-06
M18533-1|AAA53189.1| 3685|Homo sapiens dystrophin protein. 53 1e-06
L05642-1|AAA74506.1| 428|Homo sapiens dystrophin protein. 53 1e-06
AL451144-4|CAI39566.1| 3685|Homo sapiens dystrophin (muscular dy... 53 1e-06
AL139278-1|CAI42991.1| 3685|Homo sapiens dystrophin (muscular dy... 53 1e-06
AL109609-3|CAI42950.1| 3685|Homo sapiens dystrophin (muscular dy... 53 1e-06
AL096699-2|CAI42225.1| 3685|Homo sapiens dystrophin (muscular dy... 53 1e-06
AL031643-3|CAI43058.1| 3685|Homo sapiens dystrophin (muscular dy... 53 1e-06
AL031542-2|CAI42229.1| 3685|Homo sapiens dystrophin (muscular dy... 53 1e-06
BC150141-1|AAI50142.1| 1243|Homo sapiens dystrophin (muscular dy... 52 1e-06
BC127103-1|AAI27104.2| 1225|Homo sapiens DMD protein protein. 52 1e-06
AB208836-1|BAD92073.1| 1392|Homo sapiens dystrophin Dp427c isofo... 52 1e-06
AK094883-1|BAC04449.1| 775|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF233523-1|AAF65317.1| 3674|Homo sapiens beta V spectrin protein. 51 4e-06
X06178-1|CAA29544.1| 655|Homo sapiens DMD protein. 50 7e-06
BX538095-1|CAD98013.1| 1287|Homo sapiens hypothetical protein pr... 48 2e-05
AL080133-1|CAB45729.1| 1092|Homo sapiens hypothetical protein pr... 48 2e-05
AK090430-1|BAC03411.1| 1752|Homo sapiens FLJ00347 protein protein. 48 2e-05
M61877-1|AAA60577.1| 2429|Homo sapiens erythroid alpha spectrin ... 48 3e-05
M61826-1|AAA60994.1| 2429|Homo sapiens alpha-spectrin protein. 48 3e-05
AL353894-3|CAH73936.1| 2416|Homo sapiens spectrin, alpha, erythr... 48 3e-05
AL353894-2|CAH73937.1| 2419|Homo sapiens spectrin, alpha, erythr... 48 3e-05
AB033077-1|BAA86565.1| 1483|Homo sapiens KIAA1251 protein protein. 47 7e-05
BX640974-1|CAE45988.1| 899|Homo sapiens hypothetical protein pr... 46 1e-04
AK074055-1|BAB84881.1| 878|Homo sapiens FLJ00126 protein protein. 46 1e-04
M19725-1|AAA59904.1| 475|Homo sapiens SPTAN1 protein. 45 2e-04
BC036103-1|AAH36103.1| 772|Homo sapiens DMD protein protein. 44 5e-04
AL451144-5|CAI39567.1| 719|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL451144-1|CAI39563.1| 772|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL096699-3|CAI42226.1| 719|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL096699-1|CAI42224.1| 772|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL050305-1|CAI42099.1| 772|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL049643-1|CAI43007.1| 719|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL031542-3|CAI42230.1| 719|Homo sapiens dystrophin (muscular dy... 44 5e-04
AL031542-1|CAI42228.1| 772|Homo sapiens dystrophin (muscular dy... 44 5e-04
M11049-1|AAA60569.1| 237|Homo sapiens SPTA1 protein. 42 0.002
X06179-1|CAA29545.1| 209|Homo sapiens DMD protein. 40 0.008
AF083131-1|AAF98241.1| 246|Homo sapiens unknown protein. 38 0.023
AY061757-1|AAL33800.1| 763|Homo sapiens nesprin-2 beta protein. 37 0.072
M96803-1|AAA60580.1| 2364|Homo sapiens beta-spectrin protein. 35 0.22
AF327441-1|AAO15362.1| 2155|Homo sapiens beta-spectrin 2 isoform... 35 0.22
AC093110-1|AAY24229.1| 2314|Homo sapiens unknown protein. 35 0.22
AB209748-1|BAD92985.1| 2377|Homo sapiens spectrin, beta, non-ery... 35 0.22
Z70281-2|CAO03505.1| 957|Homo sapiens dystrophin related protei... 34 0.51
Z70281-1|CAO03504.1| 353|Homo sapiens dystrophin related protei... 34 0.51
Z68331-3|CAI42016.2| 957|Homo sapiens dystrophin related protei... 34 0.51
U43519-1|AAC50538.1| 954|Homo sapiens dystrophin-related protei... 34 0.51
U26396-1|AAB60364.1| 719|Homo sapiens alpha II spectrin protein. 34 0.51
M24773-1|AAA52468.1| 920|Homo sapiens alpha-fodrin protein. 34 0.51
M18627-1|AAA51702.1| 920|Homo sapiens SPTAN1 protein. 34 0.51
BC111695-1|AAI11696.2| 954|Homo sapiens dystrophin related prot... 34 0.51
AL357081-3|CAI41324.1| 675|Homo sapiens RP11-809I23.2 protein. 34 0.51
AL049548-6|CAI42747.1| 675|Homo sapiens RP11-809I23.2 protein. 34 0.51
AK056122-1|BAB71097.1| 560|Homo sapiens protein ( Homo sapiens ... 34 0.51
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 33 0.67
AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein pro... 33 0.67
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 33 0.88
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 33 0.88
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 33 0.88
BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein. 33 0.88
BC108282-1|AAI08283.1| 723|Homo sapiens RAD50 protein protein. 33 0.88
BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein. 33 0.88
BC062603-1|AAH62603.1| 557|Homo sapiens RAD50 protein protein. 33 0.88
BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain cont... 33 0.88
BC033900-1|AAH33900.1| 335|Homo sapiens NDE1 protein protein. 33 0.88
BC001421-1|AAH01421.1| 335|Homo sapiens nudE nuclear distributi... 33 0.88
AK000108-1|BAA90949.1| 335|Homo sapiens protein ( Homo sapiens ... 33 0.88
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 33 0.88
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 33 0.88
S65762-1|AAB28324.1| 1252|Homo sapiens beta-fodrin protein. 33 1.2
BC150289-1|AAI50290.1| 1362|Homo sapiens Unknown (protein for IM... 32 1.5
AY184205-1|AAO27773.1| 668|Homo sapiens nesprin-2 beta 2 protein. 32 1.5
AL357081-2|CAI41323.1| 1362|Homo sapiens spectrin repeat contain... 32 1.5
AB033088-1|BAA86576.1| 1362|Homo sapiens KIAA1262 protein protein. 32 1.5
BC003542-1|AAH03542.2| 860|Homo sapiens M-phase phosphoprotein,... 32 2.0
AL359457-4|CAI16671.1| 860|Homo sapiens M-phase phosphoprotein,... 32 2.0
AL354808-3|CAI41002.1| 860|Homo sapiens M-phase phosphoprotein,... 32 2.0
X15495-1|CAA33518.1| 58|Homo sapiens protein ( Human Duchenne ... 31 3.6
X13048-1|CAA31454.1| 58|Homo sapiens protein ( Human Duchenne ... 31 3.6
DQ480334-1|ABF19573.1| 350|Homo sapiens catecholamine-regulated... 31 4.7
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 30 6.2
BC065536-1|AAH65536.1| 1143|Homo sapiens DST protein protein. 30 6.2
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 30 6.2
AL096710-5|CAI22046.1| 3060|Homo sapiens dystonin protein. 30 6.2
AK128631-1|BAC87539.1| 544|Homo sapiens protein ( Homo sapiens ... 30 6.2
AF400227-1|AAL62062.1| 3060|Homo sapiens bullous pemphigoid anti... 30 6.2
U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated pr... 30 8.2
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 30 8.2
BC039121-1|AAH39121.1| 510|Homo sapiens SYNE1 protein protein. 30 8.2
>AL590005-3|CAI14988.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4581 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4640
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4641 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4697
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4698 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4757
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4758 HGDIDLVMNLIDNHKAFQKEL 4778
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4370 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4427
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4428 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4487
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4488 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4547
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4548 QIDEHKVFANEVNSHR 4563
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4694 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4753
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4754 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4810
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4811 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4870
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4871 ALRTLIDQHKEFMKKLEEKRA 4891
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4485 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4544
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4545 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4602
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4603 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4662
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4663 EFQKSL 4668
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 3280 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3337
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3338 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3397
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3398 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3457
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3458 HKALEDDI 3465
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 4053 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 4110
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 4111 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 4170
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 4171 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 4230
Query: 595 LH 600
+
Sbjct: 4231 AY 4232
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 4147 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 4206
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 4207 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 4264
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 4265 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 4324
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 4325 KAIEIELAKHHVLQNDV 4341
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4800 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4859
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4860 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4917
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4918 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4976
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4977 PQEIEEVKALIAEHQTFMEEM 4997
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 3161 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 3219
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 3220 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 3277
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 3278 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3337
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3338 EFKVVKAQIQEQK 3350
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3821 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3880
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3881 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3937
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3938 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3997
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3998 QISENKNVSVDM 4009
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 4254 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 4313
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 4314 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4371
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4372 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4431
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4432 LPETAKEQLNVHME 4445
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3381 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3438
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3439 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3498
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3499 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3539
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2397 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2456
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2457 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2516
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2517 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2554
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2619 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2676
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2677 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2736
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2737 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2796
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2797 ESLIKDHKDFSKTL 2810
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3712 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3771
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3772 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3829
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3830 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3889
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3890 QQEEHRQLRE 3899
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2510 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2569
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2570 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2626
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2627 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2664
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3488 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3547
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3548 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3604
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3605 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3648
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1961 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 2020
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 2021 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 2080
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 2081 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 2121
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3929 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3988
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3989 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 4046
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 4047 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 4086
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 2041 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 2099
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 2100 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 2158
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 2159 ARFSEASHKHKETLAKMEE 2177
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2843 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2899
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2900 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2959
Query: 379 KTK 387
T+
Sbjct: 2960 VTE 2962
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2952 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 3011
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 3012 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 3067
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 3068 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 3127
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 3128 IKAFLKKLEALMASN 3142
>AL590005-2|CAI14989.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 6667 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 6726
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 6727 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 6783
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 6784 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 6843
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 6844 HGDIDLVMNLIDNHKAFQKEL 6864
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 6456 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 6513
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 6514 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 6573
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 6574 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 6633
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 6634 QIDEHKVFANEVNSHR 6649
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 6780 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 6839
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 6840 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 6896
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 6897 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 6956
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 6957 ALRTLIDQHKEFMKKLEEKRA 6977
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 6571 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 6630
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 6631 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 6688
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 6689 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 6748
Query: 580 QFEEDL 597
+F++ L
Sbjct: 6749 EFQKSL 6754
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 5366 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 5423
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 5424 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 5483
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 5484 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 5543
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 5544 HKALEDDI 5551
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 6139 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 6196
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 6197 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 6256
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 6257 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 6316
Query: 595 LH 600
+
Sbjct: 6317 AY 6318
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 6233 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 6292
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 6293 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 6350
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 6351 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 6410
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 6411 KAIEIELAKHHVLQNDV 6427
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 6886 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 6945
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 6946 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 7003
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 7004 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 7062
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 7063 PQEIEEVKALIAEHQTFMEEM 7083
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 5247 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 5305
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 5306 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 5363
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 5364 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 5423
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 5424 EFKVVKAQIQEQK 5436
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 5907 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 5966
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 5967 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 6023
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 6024 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 6083
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 6084 QISENKNVSVDM 6095
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 6340 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 6399
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 6400 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 6457
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 6458 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 6517
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 6518 LPETAKEQLNVHME 6531
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 5467 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 5524
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 5525 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 5584
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 5585 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 5625
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 4483 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 4542
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 4543 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 4602
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 4603 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 4640
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 4705 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 4762
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 4763 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 4822
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 4823 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 4882
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 4883 ESLIKDHKDFSKTL 4896
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 5798 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 5857
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 5858 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 5915
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 5916 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 5975
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 5976 QQEEHRQLRE 5985
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 4596 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 4655
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 4656 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 4712
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 4713 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 4750
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 5574 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 5633
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 5634 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 5690
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 5691 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 5734
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 4047 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 4106
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 4107 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 4166
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 4167 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 4207
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 6015 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 6074
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 6075 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 6132
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 6133 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 6172
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 4127 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 4185
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 4186 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 4244
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 4245 ARFSEASHKHKETLAKMEE 4263
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 4929 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 4985
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 4986 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 5045
Query: 379 KTK 387
T+
Sbjct: 5046 VTE 5048
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 5038 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 5097
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 5098 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 5153
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 5154 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 5213
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 5214 IKAFLKKLEALMASN 5228
>AL512448-3|CAI16610.1| 5144|Homo sapiens dystonin protein.
Length = 5144
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4255 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4314
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4315 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4371
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4372 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4431
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4432 HGDIDLVMNLIDNHKAFQKEL 4452
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4044 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4101
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4102 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4161
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4162 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4221
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4222 QIDEHKVFANEVNSHR 4237
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4368 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4427
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4428 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4484
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4485 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4544
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4545 ALRTLIDQHKEFMKKLEEKRA 4565
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4159 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4218
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4219 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4276
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4277 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4336
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4337 EFQKSL 4342
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 2954 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3011
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3012 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3071
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3072 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3131
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3132 HKALEDDI 3139
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 3727 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 3784
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 3785 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 3844
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 3845 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 3904
Query: 595 LH 600
+
Sbjct: 3905 AY 3906
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 3821 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 3880
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 3881 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 3938
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 3939 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 3998
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 3999 KAIEIELAKHHVLQNDV 4015
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4474 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4534 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4591
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4592 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4650
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4651 PQEIEEVKALIAEHQTFMEEM 4671
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 2835 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 2893
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 2894 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 2951
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 2952 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3011
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3012 EFKVVKAQIQEQK 3024
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3495 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3554
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3555 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3611
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3612 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3671
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3672 QISENKNVSVDM 3683
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 3928 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 3987
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 3988 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4045
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4046 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4105
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4106 LPETAKEQLNVHME 4119
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3055 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3112
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3113 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3172
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3173 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3213
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2071 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2130
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2131 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2190
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2191 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2228
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2293 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2350
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2351 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2410
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2411 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2470
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2471 ESLIKDHKDFSKTL 2484
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3386 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3445
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3446 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3503
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3504 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3563
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3564 QQEEHRQLRE 3573
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2184 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2243
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2244 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2300
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2301 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2338
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3162 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3221
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3222 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3278
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3279 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3322
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1635 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 1694
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 1695 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 1754
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 1755 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 1795
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3603 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3662
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3663 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 3720
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 3721 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 3760
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 1715 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 1773
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 1774 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 1832
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 1833 ARFSEASHKHKETLAKMEE 1851
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2517 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2573
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2574 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2633
Query: 379 KTK 387
T+
Sbjct: 2634 VTE 2636
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2626 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 2685
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 2686 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 2741
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 2742 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 2801
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 2802 IKAFLKKLEALMASN 2816
>AL512448-2|CAI16608.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4581 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4640
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4641 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4697
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4698 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4757
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4758 HGDIDLVMNLIDNHKAFQKEL 4778
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4370 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4427
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4428 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4487
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4488 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4547
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4548 QIDEHKVFANEVNSHR 4563
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4694 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4753
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4754 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4810
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4811 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4870
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4871 ALRTLIDQHKEFMKKLEEKRA 4891
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4485 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4544
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4545 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4602
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4603 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4662
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4663 EFQKSL 4668
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 3280 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3337
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3338 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3397
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3398 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3457
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3458 HKALEDDI 3465
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 4053 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 4110
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 4111 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 4170
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 4171 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 4230
Query: 595 LH 600
+
Sbjct: 4231 AY 4232
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 4147 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 4206
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 4207 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 4264
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 4265 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 4324
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 4325 KAIEIELAKHHVLQNDV 4341
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4800 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4859
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4860 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4917
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4918 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4976
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4977 PQEIEEVKALIAEHQTFMEEM 4997
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 3161 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 3219
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 3220 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 3277
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 3278 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3337
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3338 EFKVVKAQIQEQK 3350
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3821 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3880
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3881 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3937
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3938 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3997
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3998 QISENKNVSVDM 4009
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 4254 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 4313
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 4314 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4371
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4372 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4431
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4432 LPETAKEQLNVHME 4445
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3381 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3438
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3439 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3498
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3499 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3539
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2397 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2456
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2457 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2516
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2517 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2554
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2619 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2676
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2677 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2736
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2737 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2796
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2797 ESLIKDHKDFSKTL 2810
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3712 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3771
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3772 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3829
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3830 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3889
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3890 QQEEHRQLRE 3899
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2510 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2569
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2570 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2626
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2627 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2664
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3488 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3547
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3548 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3604
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3605 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3648
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1961 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 2020
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 2021 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 2080
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 2081 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 2121
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3929 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3988
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3989 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 4046
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 4047 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 4086
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 2041 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 2099
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 2100 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 2158
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 2159 ARFSEASHKHKETLAKMEE 2177
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2843 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2899
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2900 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2959
Query: 379 KTK 387
T+
Sbjct: 2960 VTE 2962
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2952 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 3011
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 3012 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 3067
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 3068 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 3127
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 3128 IKAFLKKLEALMASN 3142
>AL512448-1|CAI16609.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 6667 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 6726
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 6727 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 6783
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 6784 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 6843
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 6844 HGDIDLVMNLIDNHKAFQKEL 6864
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 6456 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 6513
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 6514 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 6573
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 6574 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 6633
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 6634 QIDEHKVFANEVNSHR 6649
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 6780 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 6839
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 6840 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 6896
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 6897 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 6956
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 6957 ALRTLIDQHKEFMKKLEEKRA 6977
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 6571 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 6630
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 6631 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 6688
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 6689 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 6748
Query: 580 QFEEDL 597
+F++ L
Sbjct: 6749 EFQKSL 6754
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 5366 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 5423
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 5424 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 5483
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 5484 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 5543
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 5544 HKALEDDI 5551
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 6139 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 6196
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 6197 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 6256
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 6257 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 6316
Query: 595 LH 600
+
Sbjct: 6317 AY 6318
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 6233 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 6292
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 6293 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 6350
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 6351 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 6410
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 6411 KAIEIELAKHHVLQNDV 6427
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 6886 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 6945
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 6946 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 7003
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 7004 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 7062
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 7063 PQEIEEVKALIAEHQTFMEEM 7083
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 5247 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 5305
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 5306 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 5363
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 5364 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 5423
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 5424 EFKVVKAQIQEQK 5436
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 5907 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 5966
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 5967 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 6023
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 6024 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 6083
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 6084 QISENKNVSVDM 6095
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 6340 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 6399
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 6400 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 6457
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 6458 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 6517
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 6518 LPETAKEQLNVHME 6531
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 5467 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 5524
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 5525 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 5584
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 5585 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 5625
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 4483 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 4542
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 4543 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 4602
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 4603 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 4640
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 4705 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 4762
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 4763 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 4822
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 4823 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 4882
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 4883 ESLIKDHKDFSKTL 4896
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 5798 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 5857
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 5858 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 5915
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 5916 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 5975
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 5976 QQEEHRQLRE 5985
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 4596 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 4655
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 4656 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 4712
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 4713 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 4750
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 5574 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 5633
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 5634 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 5690
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 5691 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 5734
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 4047 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 4106
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 4107 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 4166
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 4167 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 4207
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 6015 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 6074
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 6075 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 6132
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 6133 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 6172
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 4127 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 4185
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 4186 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 4244
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 4245 ARFSEASHKHKETLAKMEE 4263
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 4929 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 4985
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 4986 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 5045
Query: 379 KTK 387
T+
Sbjct: 5046 VTE 5048
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 5038 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 5097
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 5098 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 5153
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 5154 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 5213
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 5214 IKAFLKKLEALMASN 5228
>AL512422-3|CAI14342.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4581 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4640
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4641 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4697
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4698 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4757
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4758 HGDIDLVMNLIDNHKAFQKEL 4778
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4370 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4427
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4428 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4487
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4488 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4547
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4548 QIDEHKVFANEVNSHR 4563
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4694 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4753
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4754 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4810
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4811 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4870
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4871 ALRTLIDQHKEFMKKLEEKRA 4891
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4485 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4544
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4545 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4602
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4603 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4662
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4663 EFQKSL 4668
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 3280 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3337
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3338 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3397
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3398 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3457
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3458 HKALEDDI 3465
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 4053 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 4110
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 4111 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 4170
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 4171 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 4230
Query: 595 LH 600
+
Sbjct: 4231 AY 4232
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 4147 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 4206
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 4207 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 4264
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 4265 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 4324
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 4325 KAIEIELAKHHVLQNDV 4341
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4800 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4859
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4860 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4917
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4918 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4976
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4977 PQEIEEVKALIAEHQTFMEEM 4997
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 3161 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 3219
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 3220 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 3277
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 3278 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3337
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3338 EFKVVKAQIQEQK 3350
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3821 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3880
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3881 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3937
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3938 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3997
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3998 QISENKNVSVDM 4009
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 4254 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 4313
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 4314 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4371
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4372 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4431
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4432 LPETAKEQLNVHME 4445
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3381 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3438
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3439 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3498
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3499 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3539
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2397 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2456
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2457 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2516
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2517 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2554
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2619 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2676
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2677 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2736
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2737 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2796
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2797 ESLIKDHKDFSKTL 2810
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3712 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3771
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3772 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3829
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3830 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3889
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3890 QQEEHRQLRE 3899
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2510 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2569
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2570 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2626
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2627 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2664
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3488 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3547
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3548 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3604
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3605 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3648
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1961 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 2020
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 2021 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 2080
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 2081 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 2121
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3929 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3988
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3989 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 4046
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 4047 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 4086
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 2041 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 2099
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 2100 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 2158
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 2159 ARFSEASHKHKETLAKMEE 2177
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2843 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2899
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2900 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2959
Query: 379 KTK 387
T+
Sbjct: 2960 VTE 2962
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2952 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 3011
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 3012 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 3067
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 3068 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 3127
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 3128 IKAFLKKLEALMASN 3142
>AL512422-2|CAI14341.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 6667 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 6726
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 6727 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 6783
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 6784 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 6843
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 6844 HGDIDLVMNLIDNHKAFQKEL 6864
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 6456 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 6513
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 6514 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 6573
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 6574 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 6633
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 6634 QIDEHKVFANEVNSHR 6649
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 6780 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 6839
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 6840 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 6896
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 6897 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 6956
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 6957 ALRTLIDQHKEFMKKLEEKRA 6977
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 6571 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 6630
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 6631 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 6688
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 6689 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 6748
Query: 580 QFEEDL 597
+F++ L
Sbjct: 6749 EFQKSL 6754
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 5366 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 5423
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 5424 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 5483
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 5484 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 5543
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 5544 HKALEDDI 5551
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 6139 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 6196
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 6197 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 6256
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 6257 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 6316
Query: 595 LH 600
+
Sbjct: 6317 AY 6318
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 6233 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 6292
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 6293 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 6350
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 6351 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 6410
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 6411 KAIEIELAKHHVLQNDV 6427
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 6886 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 6945
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 6946 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 7003
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 7004 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 7062
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 7063 PQEIEEVKALIAEHQTFMEEM 7083
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 5247 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 5305
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 5306 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 5363
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 5364 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 5423
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 5424 EFKVVKAQIQEQK 5436
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 5907 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 5966
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 5967 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 6023
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 6024 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 6083
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 6084 QISENKNVSVDM 6095
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 6340 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 6399
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 6400 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 6457
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 6458 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 6517
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 6518 LPETAKEQLNVHME 6531
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 5467 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 5524
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 5525 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 5584
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 5585 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 5625
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 4483 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 4542
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 4543 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 4602
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 4603 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 4640
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 4705 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 4762
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 4763 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 4822
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 4823 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 4882
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 4883 ESLIKDHKDFSKTL 4896
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 5798 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 5857
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 5858 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 5915
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 5916 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 5975
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 5976 QQEEHRQLRE 5985
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 4596 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 4655
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 4656 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 4712
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 4713 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 4750
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 5574 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 5633
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 5634 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 5690
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 5691 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 5734
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 4047 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 4106
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 4107 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 4166
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 4167 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 4207
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 6015 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 6074
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 6075 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 6132
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 6133 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 6172
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 4127 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 4185
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 4186 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 4244
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 4245 ARFSEASHKHKETLAKMEE 4263
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 4929 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 4985
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 4986 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 5045
Query: 379 KTK 387
T+
Sbjct: 5046 VTE 5048
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 5038 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 5097
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 5098 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 5153
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 5154 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 5213
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 5214 IKAFLKKLEALMASN 5228
>AL137008-4|CAI20332.1| 5144|Homo sapiens dystonin protein.
Length = 5144
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4255 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4314
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4315 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4371
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4372 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4431
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4432 HGDIDLVMNLIDNHKAFQKEL 4452
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4044 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4101
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4102 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4161
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4162 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4221
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4222 QIDEHKVFANEVNSHR 4237
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4368 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4427
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4428 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4484
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4485 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4544
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4545 ALRTLIDQHKEFMKKLEEKRA 4565
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4159 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4218
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4219 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4276
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4277 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4336
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4337 EFQKSL 4342
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 2954 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3011
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3012 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3071
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3072 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3131
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3132 HKALEDDI 3139
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 3727 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 3784
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 3785 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 3844
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 3845 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 3904
Query: 595 LH 600
+
Sbjct: 3905 AY 3906
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 3821 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 3880
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 3881 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 3938
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 3939 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 3998
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 3999 KAIEIELAKHHVLQNDV 4015
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4474 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4534 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4591
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4592 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4650
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4651 PQEIEEVKALIAEHQTFMEEM 4671
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 2835 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 2893
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 2894 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 2951
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 2952 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3011
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3012 EFKVVKAQIQEQK 3024
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3495 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3554
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3555 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3611
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3612 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3671
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3672 QISENKNVSVDM 3683
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 3928 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 3987
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 3988 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4045
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4046 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4105
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4106 LPETAKEQLNVHME 4119
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3055 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3112
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3113 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3172
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3173 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3213
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2071 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2130
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2131 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2190
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2191 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2228
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2293 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2350
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2351 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2410
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2411 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2470
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2471 ESLIKDHKDFSKTL 2484
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3386 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3445
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3446 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3503
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3504 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3563
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3564 QQEEHRQLRE 3573
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2184 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2243
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2244 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2300
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2301 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2338
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3162 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3221
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3222 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3278
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3279 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3322
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1635 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 1694
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 1695 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 1754
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 1755 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 1795
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3603 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3662
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3663 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 3720
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 3721 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 3760
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 1715 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 1773
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 1774 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 1832
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 1833 ARFSEASHKHKETLAKMEE 1851
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2517 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2573
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2574 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2633
Query: 379 KTK 387
T+
Sbjct: 2634 VTE 2636
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2626 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 2685
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 2686 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 2741
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 2742 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 2801
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 2802 IKAFLKKLEALMASN 2816
>AL137008-3|CAI20331.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4581 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4640
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4641 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4697
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4698 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4757
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4758 HGDIDLVMNLIDNHKAFQKEL 4778
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4370 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4427
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4428 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4487
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4488 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4547
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4548 QIDEHKVFANEVNSHR 4563
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4694 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4753
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4754 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4810
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4811 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4870
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4871 ALRTLIDQHKEFMKKLEEKRA 4891
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4485 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4544
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4545 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4602
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4603 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4662
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4663 EFQKSL 4668
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 3280 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3337
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3338 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3397
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3398 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3457
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3458 HKALEDDI 3465
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 4053 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 4110
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 4111 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 4170
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 4171 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 4230
Query: 595 LH 600
+
Sbjct: 4231 AY 4232
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 4147 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 4206
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 4207 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 4264
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 4265 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 4324
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 4325 KAIEIELAKHHVLQNDV 4341
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4800 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4859
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4860 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4917
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4918 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4976
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4977 PQEIEEVKALIAEHQTFMEEM 4997
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 3161 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 3219
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 3220 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 3277
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 3278 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3337
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3338 EFKVVKAQIQEQK 3350
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3821 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3880
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3881 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3937
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3938 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3997
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3998 QISENKNVSVDM 4009
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 4254 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 4313
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 4314 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4371
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4372 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4431
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4432 LPETAKEQLNVHME 4445
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3381 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3438
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3439 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3498
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3499 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3539
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2397 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2456
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2457 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2516
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2517 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2554
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2619 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2676
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2677 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2736
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2737 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2796
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2797 ESLIKDHKDFSKTL 2810
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3712 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3771
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3772 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3829
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3830 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3889
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3890 QQEEHRQLRE 3899
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2510 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2569
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2570 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2626
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2627 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2664
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3488 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3547
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3548 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3604
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3605 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3648
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1961 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 2020
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 2021 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 2080
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 2081 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 2121
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3929 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3988
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3989 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 4046
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 4047 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 4086
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 2041 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 2099
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 2100 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 2158
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 2159 ARFSEASHKHKETLAKMEE 2177
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2843 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2899
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2900 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2959
Query: 379 KTK 387
T+
Sbjct: 2960 VTE 2962
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2952 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 3011
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 3012 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 3067
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 3068 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 3127
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 3128 IKAFLKKLEALMASN 3142
>AL137008-2|CAI20330.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 6667 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 6726
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 6727 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 6783
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 6784 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 6843
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 6844 HGDIDLVMNLIDNHKAFQKEL 6864
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 6456 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 6513
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 6514 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 6573
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 6574 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 6633
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 6634 QIDEHKVFANEVNSHR 6649
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 6780 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 6839
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 6840 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 6896
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 6897 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 6956
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 6957 ALRTLIDQHKEFMKKLEEKRA 6977
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 6571 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 6630
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 6631 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 6688
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 6689 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 6748
Query: 580 QFEEDL 597
+F++ L
Sbjct: 6749 EFQKSL 6754
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 5366 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 5423
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 5424 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 5483
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 5484 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 5543
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 5544 HKALEDDI 5551
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 6139 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 6196
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 6197 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 6256
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 6257 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 6316
Query: 595 LH 600
+
Sbjct: 6317 AY 6318
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 6233 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 6292
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 6293 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 6350
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 6351 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 6410
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 6411 KAIEIELAKHHVLQNDV 6427
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 6886 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 6945
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 6946 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 7003
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 7004 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 7062
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 7063 PQEIEEVKALIAEHQTFMEEM 7083
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 5247 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 5305
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 5306 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 5363
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 5364 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 5423
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 5424 EFKVVKAQIQEQK 5436
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 5907 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 5966
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 5967 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 6023
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 6024 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 6083
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 6084 QISENKNVSVDM 6095
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 6340 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 6399
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 6400 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 6457
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 6458 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 6517
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 6518 LPETAKEQLNVHME 6531
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 5467 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 5524
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 5525 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 5584
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 5585 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 5625
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 4483 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 4542
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 4543 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 4602
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 4603 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 4640
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 4705 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 4762
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 4763 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 4822
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 4823 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 4882
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 4883 ESLIKDHKDFSKTL 4896
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 5798 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 5857
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 5858 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 5915
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 5916 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 5975
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 5976 QQEEHRQLRE 5985
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 4596 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 4655
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 4656 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 4712
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 4713 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 4750
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 5574 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 5633
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 5634 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 5690
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 5691 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 5734
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 4047 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 4106
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 4107 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 4166
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 4167 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 4207
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 6015 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 6074
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 6075 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 6132
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 6133 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 6172
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 4127 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 4185
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 4186 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 4244
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 4245 ARFSEASHKHKETLAKMEE 4263
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 4929 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 4985
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 4986 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 5045
Query: 379 KTK 387
T+
Sbjct: 5046 VTE 5048
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 5038 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 5097
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 5098 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 5153
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 5154 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 5213
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 5214 IKAFLKKLEALMASN 5228
>AL096710-4|CAI22045.1| 5144|Homo sapiens dystonin protein.
Length = 5144
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4255 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4314
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4315 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4371
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4372 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4431
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4432 HGDIDLVMNLIDNHKAFQKEL 4452
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4044 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4101
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4102 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4161
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4162 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4221
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4222 QIDEHKVFANEVNSHR 4237
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4368 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4427
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4428 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4484
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4485 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4544
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4545 ALRTLIDQHKEFMKKLEEKRA 4565
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4159 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4218
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4219 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4276
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4277 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4336
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4337 EFQKSL 4342
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 2954 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3011
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3012 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3071
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3072 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3131
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3132 HKALEDDI 3139
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 3727 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 3784
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 3785 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 3844
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 3845 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 3904
Query: 595 LH 600
+
Sbjct: 3905 AY 3906
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 3821 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 3880
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 3881 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 3938
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 3939 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 3998
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 3999 KAIEIELAKHHVLQNDV 4015
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4474 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4534 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4591
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4592 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4650
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4651 PQEIEEVKALIAEHQTFMEEM 4671
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 2835 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 2893
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 2894 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 2951
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 2952 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3011
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3012 EFKVVKAQIQEQK 3024
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3495 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3554
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3555 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3611
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3612 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3671
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3672 QISENKNVSVDM 3683
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 3928 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 3987
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 3988 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4045
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4046 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4105
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4106 LPETAKEQLNVHME 4119
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3055 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3112
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3113 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3172
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3173 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3213
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2071 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2130
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2131 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2190
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2191 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2228
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2293 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2350
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2351 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2410
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2411 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2470
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2471 ESLIKDHKDFSKTL 2484
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3386 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3445
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3446 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3503
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3504 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3563
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3564 QQEEHRQLRE 3573
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2184 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2243
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2244 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2300
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2301 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2338
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3162 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3221
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3222 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3278
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3279 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3322
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1635 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 1694
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 1695 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 1754
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 1755 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 1795
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3603 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3662
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3663 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 3720
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 3721 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 3760
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 1715 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 1773
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 1774 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 1832
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 1833 ARFSEASHKHKETLAKMEE 1851
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2517 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2573
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2574 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2633
Query: 379 KTK 387
T+
Sbjct: 2634 VTE 2636
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2626 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 2685
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 2686 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 2741
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 2742 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 2801
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 2802 IKAFLKKLEALMASN 2816
>AL096710-3|CAI22043.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4581 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4640
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4641 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4697
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4698 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4757
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4758 HGDIDLVMNLIDNHKAFQKEL 4778
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4370 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4427
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4428 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4487
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4488 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4547
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4548 QIDEHKVFANEVNSHR 4563
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4694 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4753
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 4754 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 4810
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4811 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4870
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4871 ALRTLIDQHKEFMKKLEEKRA 4891
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4485 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4544
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4545 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4602
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4603 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4662
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4663 EFQKSL 4668
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 3280 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3337
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3338 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3397
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3398 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3457
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3458 HKALEDDI 3465
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 4053 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 4110
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 4111 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 4170
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 4171 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 4230
Query: 595 LH 600
+
Sbjct: 4231 AY 4232
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 4147 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 4206
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 4207 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 4264
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 4265 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 4324
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 4325 KAIEIELAKHHVLQNDV 4341
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4800 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4859
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4860 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4917
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4918 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4976
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4977 PQEIEEVKALIAEHQTFMEEM 4997
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 3161 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 3219
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 3220 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 3277
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 3278 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3337
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3338 EFKVVKAQIQEQK 3350
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3821 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3880
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 3881 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3937
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3938 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3997
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3998 QISENKNVSVDM 4009
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 4254 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 4313
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 4314 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 4371
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4372 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4431
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4432 LPETAKEQLNVHME 4445
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3381 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3438
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3439 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3498
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3499 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3539
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2397 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2456
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2457 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2516
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2517 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2554
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2619 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2676
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2677 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2736
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2737 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2796
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2797 ESLIKDHKDFSKTL 2810
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3712 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3771
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3772 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3829
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3830 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3889
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 3890 QQEEHRQLRE 3899
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2510 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2569
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2570 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2626
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2627 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2664
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3488 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3547
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3548 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3604
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3605 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3648
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1961 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 2020
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 2021 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 2080
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 2081 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 2121
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3929 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3988
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3989 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 4046
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 4047 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 4086
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 2041 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 2099
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 2100 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 2158
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 2159 ARFSEASHKHKETLAKMEE 2177
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2843 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2899
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2900 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 2959
Query: 379 KTK 387
T+
Sbjct: 2960 VTE 2962
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2952 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 3011
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 3012 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 3067
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 3068 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 3127
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 3128 IKAFLKKLEALMASN 3142
>AL096710-2|CAI22044.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 6667 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 6726
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 6727 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 6783
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 6784 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 6843
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 6844 HGDIDLVMNLIDNHKAFQKEL 6864
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 6456 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 6513
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 6514 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 6573
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 6574 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 6633
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 6634 QIDEHKVFANEVNSHR 6649
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 6780 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 6839
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 6840 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 6896
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 6897 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 6956
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 6957 ALRTLIDQHKEFMKKLEEKRA 6977
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 6571 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 6630
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 6631 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 6688
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 6689 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 6748
Query: 580 QFEEDL 597
+F++ L
Sbjct: 6749 EFQKSL 6754
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 5366 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 5423
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 5424 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 5483
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 5484 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 5543
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 5544 HKALEDDI 5551
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 6139 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 6196
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 6197 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 6256
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 6257 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 6316
Query: 595 LH 600
+
Sbjct: 6317 AY 6318
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 6233 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 6292
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 6293 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 6350
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 6351 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 6410
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 6411 KAIEIELAKHHVLQNDV 6427
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 6886 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 6945
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 6946 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 7003
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 7004 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 7062
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 7063 PQEIEEVKALIAEHQTFMEEM 7083
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 5247 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 5305
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 5306 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 5363
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 5364 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 5423
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 5424 EFKVVKAQIQEQK 5436
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 5907 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 5966
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 5967 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 6023
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 6024 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 6083
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 6084 QISENKNVSVDM 6095
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 6340 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 6399
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 6400 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 6457
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 6458 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 6517
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 6518 LPETAKEQLNVHME 6531
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 5467 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 5524
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 5525 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 5584
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 5585 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 5625
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 4483 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 4542
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 4543 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 4602
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 4603 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 4640
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 4705 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 4762
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 4763 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 4822
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 4823 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 4882
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 4883 ESLIKDHKDFSKTL 4896
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 5798 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 5857
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 5858 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 5915
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 5916 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 5975
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 5976 QQEEHRQLRE 5985
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 4596 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 4655
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 4656 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 4712
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 4713 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 4750
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 5574 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 5633
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 5634 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 5690
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 5691 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 5734
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 4047 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 4106
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 4107 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 4166
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 4167 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 4207
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 6015 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 6074
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 6075 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 6132
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 6133 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 6172
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 4127 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 4185
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 4186 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 4244
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 4245 ARFSEASHKHKETLAKMEE 4263
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 678 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 733
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 734 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 791
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 792 QLCQCVEQHIKENTAYFEFFNDAKEA 817
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 1270 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1328
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1329 TQLNQQKMLVSEIEMKQSKMDECQK 1353
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 4929 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 4985
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 4986 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 5045
Query: 379 KTK 387
T+
Sbjct: 5046 VTE 5048
Score = 29.9 bits (64), Expect = 8.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 5038 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 5097
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 5098 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 5153
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 5154 TLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 5213
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 5214 IKAFLKKLEALMASN 5228
>AF400226-1|AAL62061.1| 5171|Homo sapiens bullous pemphigoid antigen 1
eA protein.
Length = 5171
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 4255 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 4314
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 4315 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 4371
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 4372 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 4431
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 4432 HGDIDLVMNLIDNHKAFQKEL 4452
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 4044 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 4101
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 4102 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 4161
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 4162 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 4221
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 4222 QIDEHKVFANEVNSHR 4237
Score = 99 bits (238), Expect = 7e-21
Identities = 52/201 (25%), Positives = 100/201 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 4368 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 4427
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + D + +K +
Sbjct: 4428 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIXGS-RDDSSWVKVQM 4484
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 4485 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 4544
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 4545 ALRTLIDQHKEFMKKLEEKRA 4565
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 4159 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 4218
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 4219 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 4276
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 4277 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 4336
Query: 580 QFEEDL 597
+F++ L
Sbjct: 4337 EFQKSL 4342
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 2954 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 3011
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 3012 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 3071
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 3072 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 3131
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 3132 HKALEDDI 3139
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 3727 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEGPGI--DPSVVKQ 3784
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 3785 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 3844
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 3845 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 3904
Query: 595 LH 600
+
Sbjct: 3905 AY 3906
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 3821 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 3880
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 3881 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 3938
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 3939 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 3998
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 3999 KAIEIELAKHHVLQNDV 4015
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 4474 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 4533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 4534 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 4591
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 4592 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 4650
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 4651 PQEIEEVKALIAEHQTFMEEM 4671
Score = 64.5 bits (150), Expect = 3e-10
Identities = 48/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L EE +
Sbjct: 2835 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQRAEEHEE- 2893
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 2894 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 2951
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 2952 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 3011
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 3012 EFKVVKAQIQEQK 3024
Score = 61.7 bits (143), Expect = 2e-09
Identities = 40/192 (20%), Positives = 86/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 3495 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 3554
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++++A +P D KTG L + +P G+ ++
Sbjct: 3555 AL--EYETLRQQQEEHRQLRESIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 3611
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 3612 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKE 3671
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 3672 QISENKNVSVDM 3683
Score = 56.4 bits (130), Expect = 8e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 3928 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 3987
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 3988 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKGGNDLIESSAGEEASNLQ 4045
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 4046 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 4105
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 4106 LPETAKEQLNVHME 4119
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 3055 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 3112
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 3113 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 3172
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 3173 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 3213
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 2071 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 2130
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 2131 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 2190
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 2191 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 2228
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 2293 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 2350
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 2351 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 2410
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 2411 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 2470
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 2471 ESLIKDHKDFSKTL 2484
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/192 (16%), Positives = 75/192 (39%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 3386 LEKMVAEDNERYRLVSDTITQKVEEVDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 3445
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 3446 RL--EQDQTSAQLQVQKTFTMEILRHRDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 3503
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 3504 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 3563
Query: 562 LIEQHKQFEEDL 597
E+H+Q E +
Sbjct: 3564 QQEEHRQLRESI 3575
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 2184 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 2243
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 2244 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLRGIVKEQLAA 2300
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 2301 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 2338
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 3162 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 3221
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 3222 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 3278
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 3279 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 3322
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
+ + D L+ L E + SE DP ++++L + + Q ++S+Q A +
Sbjct: 1635 QHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKL 1694
Query: 301 MKTGKHLKDKAPK--GDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAM 474
KT + L D +N ++ + D+ ++ + +R KL+ L S +D +
Sbjct: 1695 KKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGL 1754
Query: 475 SALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+LDW + V + + +I ++ E+D+
Sbjct: 1755 DEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDI 1795
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 3603 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 3662
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 3663 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 3720
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 3721 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 3760
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/139 (15%), Positives = 57/139 (41%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L + R+E + ER L + D + +++W+ E L + +
Sbjct: 1715 IQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKE-QGQ 1773
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+N ++ ++K+ ++ +A +Q + + + K + + L+ + D+
Sbjct: 1774 VPLNS-TALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLS 1832
Query: 382 TKWTTVCSKAVDRQRKLEE 438
+++ K + K+EE
Sbjct: 1833 ARFSEASHKHKETLAKMEE 1851
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 30.3 bits (65), Expect = 6.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 2517 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 2573
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 2574 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKGVVTDENKSLIQKVDM 2633
Query: 379 KTK 387
T+
Sbjct: 2634 VTE 2636
Score = 30.3 bits (65), Expect = 6.2
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 2/195 (1%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ + + V + + L++ ++ KEF ++ L +EQLD +S +
Sbjct: 2626 SLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYS 2685
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPLKTMITDMKTKWT 393
+K L QK+L + + DL + + L +A KG + L + T + + +
Sbjct: 2686 NKYLTMLQTQ---QKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVET-IAQEHS 2741
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
T+ + ++ LE L G F++ + + + APV D +T+ E
Sbjct: 2742 TLSQQVDEKCSFLETKLQGIGHFRNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKET 2801
Query: 574 HKQFEEDLHFARAAD 618
K F + L A++
Sbjct: 2802 IKAFLKKLEALMASN 2816
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
>AB018271-1|BAA34448.2| 1637|Homo sapiens KIAA0728 protein protein.
Length = 1637
Score = 225 bits (550), Expect = 1e-58
Identities = 106/201 (52%), Positives = 142/201 (70%), Gaps = 2/201 (0%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLL+SVQ RWE+VV + ER R+LD K AK+F + W+ LM WL E+E+
Sbjct: 721 QKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKS 780
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN-P 354
LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+K D+N
Sbjct: 781 LD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLK 837
Query: 355 LKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW D PV
Sbjct: 838 LDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPV 897
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
HGD+D VM LI+ HK F+++L
Sbjct: 898 HGDIDLVMNLIDNHKAFQKEL 918
Score = 103 bits (248), Expect = 4e-22
Identities = 58/196 (29%), Positives = 101/196 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 510 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 567
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
P+ K++LN H E A +K+ Y M+ G+ + + PK E + I ++K
Sbjct: 568 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLK 627
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
KW +V +K +R+ KLEEAL + +F +++ ++W + LDTV+
Sbjct: 628 EKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLF 687
Query: 562 LIEQHKQFEEDLHFAR 609
I++HK F +++ R
Sbjct: 688 QIDEHKVFANEVNSHR 703
Score = 101 bits (241), Expect = 3e-21
Identities = 52/201 (25%), Positives = 101/201 (50%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 834 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 893
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ D D + ++ H+ FQK L + + ++ + L + + + D + +K +
Sbjct: 894 --DQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGS-RDDSSWVKVQM 950
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++ T+W TVC+ ++ +Q +LE AL + +F + ALL+W + D D
Sbjct: 951 QELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDED 1010
Query: 550 TVMALIEQHKQFEEDLHFARA 612
+ LI+QHK+F + L RA
Sbjct: 1011 ALRTLIDQHKEFMKKLEEKRA 1031
Score = 93.5 bits (222), Expect = 6e-19
Identities = 48/186 (25%), Positives = 95/186 (51%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+++ +WE V +K ER L+ A EF + + +NWL + E+ L+ + + + D
Sbjct: 625 NLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDT 684
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ ++++H+ F + S + KTG HLK + K D +K ++ ++++W V
Sbjct: 685 --VLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKV 742
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ V+R R L++A + QF +A S L++W + + + D D + + QHK
Sbjct: 743 VQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHK 802
Query: 580 QFEEDL 597
+F++ L
Sbjct: 803 EFQKSL 808
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 193 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 250
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 251 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 310
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 311 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 370
Query: 595 LH 600
+
Sbjct: 371 AY 372
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 287 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 346
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 347 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 404
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 405 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 464
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 465 KAIEIELAKHHVLQNDV 481
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/201 (22%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K + + RWE V + S + L+ ++A+EF + + L+ WL E E+ L
Sbjct: 940 RDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTL 999
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ + +D D ++ +++H+EF K L K+ + G + +K
Sbjct: 1000 -RFHG-VLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKH 1057
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++L A L+ + +A+ A L W + + +
Sbjct: 1058 WITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEV-I 1116
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
+++ V ALI +H+ F E++
Sbjct: 1117 PQEIEEVKALIAEHQTFMEEM 1137
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 394 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 453
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 454 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 511
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 512 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 571
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 572 LPETAKEQLNVHME 585
Score = 51.6 bits (118), Expect = 2e-06
Identities = 33/150 (22%), Positives = 68/150 (45%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
L WL ET+ + QL + A + + ++Q+ +HR+ ++ +A +P D KTG L +
Sbjct: 3 LWPWLTETQSIISQLPAPAL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLE 60
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
+P G+ ++ T ++ + R L+EA+ S QF D + +L+
Sbjct: 61 LSP-GEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIV 119
Query: 508 XXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+ +++ + I ++K D+
Sbjct: 120 ERLRQPPSISAEVEKIKEQISENKNVSVDM 149
Score = 38.7 bits (86), Expect = 0.018
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + ++ +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 69 IQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 128
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 129 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 186
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 187 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 226
>AL442071-4|CAH73671.1| 5938|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5938
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 5058 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 5117
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 5118 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 5173
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 5174 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 5233
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 5234 VHGDLDLVMNLMDAHKVFQKEL 5255
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 5170 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 5229
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 5230 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 5286
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 5287 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 5346
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 5347 EALQSLIDTHKEF 5359
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4842 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4901
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4902 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4959
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4960 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 5019
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 5020 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 5050
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4963 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 5021
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 5022 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 5080
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 5081 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 5140
Query: 583 FEEDL 597
F++ L
Sbjct: 5141 FQKTL 5145
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3745 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3802
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3803 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3862
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3863 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3922
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3923 KIQQQIIRHKALEEDI 3938
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4627 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4686
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4687 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4744
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4745 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4804
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4805 VELAKHHVLKNDV 4817
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 5277 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 5336
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 5337 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 5394
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 5395 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 5453
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 5454 PQNIDRVKALIAEHQTFMEEM 5474
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4736 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4793
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4794 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4853
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4854 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4913
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4914 EQLDTHMELYSQL 4926
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 3203 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 3260
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 3261 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 3320
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 3321 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 3358
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 4071 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 4130
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 4131 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 4188
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 4189 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 4248
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 4249 DQTTAQLQVQKAFSIDI 4265
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3858 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3915
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3916 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3975
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3976 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 4012
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3634 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3691
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3692 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3751
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3752 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3811
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3812 YKVVKAQIQEQKLLQRLLDDRKA 3834
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2865 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2924
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2925 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2984
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2985 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 3027
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 2403 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 2462
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 2463 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2522
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2523 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2560
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 4401 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 4460
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 4461 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4520
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4521 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4561
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2983 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 3042
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 3043 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 3098
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 3099 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 3158
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 3159 VKQQLEETSEIRSDL 3173
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 3313 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 3370
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 3371 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 3428
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 3429 QNMDAVTEELQAKTGSLEEMTQRLREFQES 3458
>AL442071-2|CAH73669.1| 4433|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 4433
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 3559 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 3618
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 3619 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 3674
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 3675 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 3734
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 3735 VHGDLDLVMNLMDAHKVFQKEL 3756
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 3671 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 3730
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 3731 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 3787
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 3788 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 3847
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 3848 EALQSLIDTHKEF 3860
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 3343 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 3402
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 3403 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 3460
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 3461 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 3520
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 3521 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 3551
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 3464 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 3522
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 3523 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 3581
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 3582 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 3641
Query: 583 FEEDL 597
F++ L
Sbjct: 3642 FQKTL 3646
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 3128 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 3187
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 3188 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 3245
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 3246 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 3305
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 3306 VELAKHHVLKNDV 3318
Score = 77.4 bits (182), Expect = 4e-14
Identities = 43/196 (21%), Positives = 86/196 (43%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 2355 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 2412
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 2413 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 2472
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 2473 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 2532
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK E++
Sbjct: 2533 KIQQQIIRHKALNEEI 2548
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 3778 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 3837
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 3838 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 3895
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 3896 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 3954
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 3955 PQNIDRVKALIAEHQTFMEEM 3975
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 3237 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 3294
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 3295 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 3354
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 3355 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 3414
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 3415 EQLDTHMELYSQL 3427
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 1813 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 1870
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 1871 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 1930
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 1931 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 1968
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 2572 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 2631
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 2632 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 2689
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 2690 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 2749
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 2750 DQTTAQLQVQKAFSIDI 2766
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/157 (23%), Positives = 78/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 2468 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 2525
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ + + +++ D +K G+ L + + ++ + +K
Sbjct: 2526 PVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIK 2585
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
T++ + + R LE+A + +F+ L W
Sbjct: 2586 TRYADITVTSSKALRTLEQARQLATKFQSTYEELTGW 2622
Score = 50.8 bits (116), Expect = 4e-06
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 1474 KTDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVL 1533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 1534 KSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWK 1593
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 1594 KIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 1637
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 2244 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 2301
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 2302 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 2361
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 2362 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 2421
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 2422 YKVVKAQIQEQKLLQRLLDDRKA 2444
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1034 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1093
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1094 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1153
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1154 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 1191
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 2902 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 2961
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 2962 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 3021
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 3022 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 3062
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 1593 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 1652
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 1653 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 1708
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 1709 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 1768
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 1769 VKQQLEETSEIRSDL 1783
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 1923 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 1980
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 1981 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2038
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2039 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2068
>AL442071-1|CAH73668.1| 5430|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5430
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4556 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4615
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4616 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 4671
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4672 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4731
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4732 VHGDLDLVMNLMDAHKVFQKEL 4753
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4668 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4727
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4728 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4784
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 4785 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 4844
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 4845 EALQSLIDTHKEF 4857
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4340 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4399
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4400 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4457
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4458 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4517
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4518 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4548
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4461 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4519
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4520 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4578
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4579 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4638
Query: 583 FEEDL 597
F++ L
Sbjct: 4639 FQKTL 4643
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3243 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3300
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3301 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3360
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3361 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3420
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3421 KIQQQIIRHKALEEDI 3436
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4125 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4184
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4185 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4242
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4243 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4302
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4303 VELAKHHVLKNDV 4315
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 4775 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 4834
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 4835 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 4892
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 4893 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 4951
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 4952 PQNIDRVKALIAEHQTFMEEM 4972
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4234 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4291
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4292 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4351
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4352 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4411
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4412 EQLDTHMELYSQL 4424
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2701 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2758
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2759 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2818
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2819 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2856
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3569 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3628
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3629 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3686
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3687 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3746
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3747 DQTTAQLQVQKAFSIDI 3763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3356 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3413
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3414 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3473
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3474 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3510
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3132 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3189
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3190 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3249
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3250 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3309
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3310 YKVVKAQIQEQKLLQRLLDDRKA 3332
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2363 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2422
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2423 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2482
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2483 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 2525
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1901 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1960
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1961 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2020
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2021 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2058
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3899 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3958
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3959 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4018
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4019 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4059
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2481 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 2540
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2541 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2596
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2597 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2656
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2657 VKQQLEETSEIRSDL 2671
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2811 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2868
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2869 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2926
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2927 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2956
>AL365277-12|CAI16422.1| 5938|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5938
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 5058 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 5117
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 5118 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 5173
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 5174 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 5233
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 5234 VHGDLDLVMNLMDAHKVFQKEL 5255
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 5170 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 5229
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 5230 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 5286
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 5287 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 5346
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 5347 EALQSLIDTHKEF 5359
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4842 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4901
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4902 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4959
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4960 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 5019
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 5020 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 5050
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4963 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 5021
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 5022 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 5080
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 5081 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 5140
Query: 583 FEEDL 597
F++ L
Sbjct: 5141 FQKTL 5145
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3745 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3802
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3803 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3862
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3863 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3922
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3923 KIQQQIIRHKALEEDI 3938
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4627 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4686
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4687 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4744
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4745 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4804
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4805 VELAKHHVLKNDV 4817
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 5277 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 5336
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 5337 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 5394
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 5395 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 5453
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 5454 PQNIDRVKALIAEHQTFMEEM 5474
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4736 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4793
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4794 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4853
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4854 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4913
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4914 EQLDTHMELYSQL 4926
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 3203 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 3260
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 3261 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 3320
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 3321 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 3358
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 4071 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 4130
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 4131 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 4188
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 4189 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 4248
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 4249 DQTTAQLQVQKAFSIDI 4265
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3858 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3915
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3916 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3975
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3976 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 4012
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3634 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3691
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3692 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3751
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3752 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3811
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3812 YKVVKAQIQEQKLLQRLLDDRKA 3834
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2865 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2924
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2925 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2984
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2985 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 3027
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 2403 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 2462
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 2463 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2522
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2523 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2560
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 4401 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 4460
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 4461 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4520
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4521 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4561
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2983 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 3042
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 3043 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 3098
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 3099 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 3158
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 3159 VKQQLEETSEIRSDL 3173
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 3313 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 3370
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 3371 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 3428
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 3429 QNMDAVTEELQAKTGSLEEMTQRLREFQES 3458
>AL365277-10|CAI16420.1| 4433|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 4433
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 3559 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 3618
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 3619 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 3674
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 3675 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 3734
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 3735 VHGDLDLVMNLMDAHKVFQKEL 3756
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 3671 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 3730
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 3731 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 3787
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 3788 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 3847
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 3848 EALQSLIDTHKEF 3860
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 3343 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 3402
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 3403 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 3460
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 3461 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 3520
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 3521 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 3551
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 3464 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 3522
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 3523 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 3581
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 3582 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 3641
Query: 583 FEEDL 597
F++ L
Sbjct: 3642 FQKTL 3646
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 3128 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 3187
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 3188 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 3245
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 3246 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 3305
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 3306 VELAKHHVLKNDV 3318
Score = 77.4 bits (182), Expect = 4e-14
Identities = 43/196 (21%), Positives = 86/196 (43%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 2355 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 2412
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 2413 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 2472
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 2473 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 2532
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK E++
Sbjct: 2533 KIQQQIIRHKALNEEI 2548
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 3778 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 3837
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 3838 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 3895
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 3896 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 3954
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 3955 PQNIDRVKALIAEHQTFMEEM 3975
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 3237 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 3294
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 3295 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 3354
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 3355 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 3414
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 3415 EQLDTHMELYSQL 3427
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 1813 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 1870
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 1871 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 1930
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 1931 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 1968
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 2572 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 2631
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 2632 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 2689
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 2690 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 2749
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 2750 DQTTAQLQVQKAFSIDI 2766
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/157 (23%), Positives = 78/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 2468 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 2525
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ + + +++ D +K G+ L + + ++ + +K
Sbjct: 2526 PVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIK 2585
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
T++ + + R LE+A + +F+ L W
Sbjct: 2586 TRYADITVTSSKALRTLEQARQLATKFQSTYEELTGW 2622
Score = 50.8 bits (116), Expect = 4e-06
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 1474 KTDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVL 1533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 1534 KSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWK 1593
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 1594 KIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 1637
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 2244 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 2301
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 2302 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 2361
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 2362 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 2421
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 2422 YKVVKAQIQEQKLLQRLLDDRKA 2444
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1034 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1093
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1094 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1153
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1154 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 1191
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 2902 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 2961
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 2962 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 3021
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 3022 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 3062
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 1593 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 1652
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 1653 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 1708
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 1709 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 1768
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 1769 VKQQLEETSEIRSDL 1783
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 1923 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 1980
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 1981 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2038
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2039 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2068
>AL365277-7|CAI16417.1| 5430|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5430
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4556 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4615
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4616 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 4671
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4672 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4731
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4732 VHGDLDLVMNLMDAHKVFQKEL 4753
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4668 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4727
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4728 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4784
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 4785 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 4844
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 4845 EALQSLIDTHKEF 4857
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4340 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4399
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4400 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4457
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4458 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4517
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4518 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4548
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4461 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4519
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4520 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4578
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4579 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4638
Query: 583 FEEDL 597
F++ L
Sbjct: 4639 FQKTL 4643
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3243 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3300
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3301 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3360
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3361 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3420
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3421 KIQQQIIRHKALEEDI 3436
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4125 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4184
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4185 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4242
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4243 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4302
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4303 VELAKHHVLKNDV 4315
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 4775 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 4834
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 4835 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 4892
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 4893 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 4951
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 4952 PQNIDRVKALIAEHQTFMEEM 4972
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4234 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4291
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4292 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4351
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4352 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4411
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4412 EQLDTHMELYSQL 4424
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2701 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2758
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2759 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2818
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2819 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2856
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3569 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3628
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3629 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3686
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3687 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3746
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3747 DQTTAQLQVQKAFSIDI 3763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3356 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3413
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3414 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3473
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3474 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3510
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3132 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3189
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3190 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3249
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3250 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3309
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3310 YKVVKAQIQEQKLLQRLLDDRKA 3332
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2363 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2422
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2423 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2482
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2483 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 2525
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1901 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1960
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1961 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2020
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2021 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2058
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3899 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3958
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3959 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4018
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4019 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4059
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2481 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 2540
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2541 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2596
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2597 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2656
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2657 VKQQLEETSEIRSDL 2671
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2811 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2868
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2869 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2926
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2927 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2956
>AL355477-1|CAH70156.1| 5430|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5430
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4556 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4615
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4616 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 4671
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4672 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4731
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4732 VHGDLDLVMNLMDAHKVFQKEL 4753
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4668 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4727
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4728 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4784
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 4785 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 4844
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 4845 EALQSLIDTHKEF 4857
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4340 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4399
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4400 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4457
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4458 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4517
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4518 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4548
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4461 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4519
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4520 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4578
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4579 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4638
Query: 583 FEEDL 597
F++ L
Sbjct: 4639 FQKTL 4643
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3243 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3300
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3301 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3360
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3361 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3420
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3421 KIQQQIIRHKALEEDI 3436
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4125 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4184
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4185 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4242
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4243 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4302
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4303 VELAKHHVLKNDV 4315
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 4775 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 4834
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 4835 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 4892
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 4893 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 4951
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 4952 PQNIDRVKALIAEHQTFMEEM 4972
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4234 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4291
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4292 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4351
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4352 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4411
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4412 EQLDTHMELYSQL 4424
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2701 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2758
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2759 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2818
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2819 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2856
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3569 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3628
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3629 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3686
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3687 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3746
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3747 DQTTAQLQVQKAFSIDI 3763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3356 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3413
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3414 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3473
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3474 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3510
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3132 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3189
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3190 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3249
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3250 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3309
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3310 YKVVKAQIQEQKLLQRLLDDRKA 3332
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2363 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2422
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2423 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2482
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2483 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 2525
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1901 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1960
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1961 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2020
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2021 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2058
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3899 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3958
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3959 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4018
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4019 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4059
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2481 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 2540
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2541 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2596
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2597 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2656
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2657 VKQQLEETSEIRSDL 2671
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2811 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2868
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2869 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2926
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2927 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2956
>AL137853-3|CAI21816.1| 5938|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5938
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 5058 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 5117
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 5118 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 5173
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 5174 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 5233
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 5234 VHGDLDLVMNLMDAHKVFQKEL 5255
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 5170 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 5229
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 5230 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 5286
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 5287 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 5346
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 5347 EALQSLIDTHKEF 5359
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4842 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4901
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4902 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4959
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4960 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 5019
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 5020 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 5050
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4963 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 5021
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 5022 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 5080
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 5081 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 5140
Query: 583 FEEDL 597
F++ L
Sbjct: 5141 FQKTL 5145
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3745 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3802
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3803 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3862
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3863 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3922
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3923 KIQQQIIRHKALEEDI 3938
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4627 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4686
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4687 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4744
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4745 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4804
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4805 VELAKHHVLKNDV 4817
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 5277 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 5336
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 5337 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 5394
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 5395 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 5453
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 5454 PQNIDRVKALIAEHQTFMEEM 5474
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4736 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4793
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4794 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4853
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4854 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4913
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4914 EQLDTHMELYSQL 4926
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 3203 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 3260
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 3261 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 3320
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 3321 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 3358
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 4071 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 4130
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 4131 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 4188
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 4189 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 4248
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 4249 DQTTAQLQVQKAFSIDI 4265
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3858 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3915
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3916 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3975
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3976 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 4012
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3634 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3691
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3692 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3751
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3752 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3811
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3812 YKVVKAQIQEQKLLQRLLDDRKA 3834
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2865 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2924
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2925 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2984
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2985 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 3027
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 2403 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 2462
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 2463 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2522
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2523 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2560
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 4401 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 4460
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 4461 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4520
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4521 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4561
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2983 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 3042
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 3043 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 3098
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 3099 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 3158
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 3159 VKQQLEETSEIRSDL 3173
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 3313 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 3370
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 3371 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 3428
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 3429 QNMDAVTEELQAKTGSLEEMTQRLREFQES 3458
>AL137853-2|CAI21815.1| 4433|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 4433
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 3559 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 3618
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 3619 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 3674
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 3675 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 3734
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 3735 VHGDLDLVMNLMDAHKVFQKEL 3756
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 3671 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 3730
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 3731 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 3787
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 3788 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 3847
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 3848 EALQSLIDTHKEF 3860
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 3343 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 3402
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 3403 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 3460
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 3461 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 3520
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 3521 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 3551
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 3464 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 3522
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 3523 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 3581
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 3582 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 3641
Query: 583 FEEDL 597
F++ L
Sbjct: 3642 FQKTL 3646
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 3128 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 3187
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 3188 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 3245
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 3246 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 3305
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 3306 VELAKHHVLKNDV 3318
Score = 77.4 bits (182), Expect = 4e-14
Identities = 43/196 (21%), Positives = 86/196 (43%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 2355 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 2412
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 2413 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 2472
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 2473 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 2532
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK E++
Sbjct: 2533 KIQQQIIRHKALNEEI 2548
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 3778 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 3837
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 3838 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 3895
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 3896 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 3954
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 3955 PQNIDRVKALIAEHQTFMEEM 3975
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 3237 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 3294
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 3295 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 3354
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 3355 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 3414
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 3415 EQLDTHMELYSQL 3427
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 1813 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 1870
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 1871 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 1930
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 1931 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 1968
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 2572 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 2631
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 2632 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 2689
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 2690 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 2749
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 2750 DQTTAQLQVQKAFSIDI 2766
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/157 (23%), Positives = 78/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 2468 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 2525
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ + + +++ D +K G+ L + + ++ + +K
Sbjct: 2526 PVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIK 2585
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
T++ + + R LE+A + +F+ L W
Sbjct: 2586 TRYADITVTSSKALRTLEQARQLATKFQSTYEELTGW 2622
Score = 50.8 bits (116), Expect = 4e-06
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 1474 KTDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVL 1533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 1534 KSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWK 1593
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 1594 KIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 1637
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 2244 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 2301
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 2302 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 2361
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 2362 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 2421
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 2422 YKVVKAQIQEQKLLQRLLDDRKA 2444
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1034 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1093
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1094 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1153
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1154 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 1191
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 2902 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 2961
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 2962 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 3021
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 3022 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 3062
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 1593 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 1652
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 1653 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 1708
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 1709 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 1768
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 1769 VKQQLEETSEIRSDL 1783
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 1923 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 1980
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 1981 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2038
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2039 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2068
>AL137853-1|CAI21814.1| 5430|Homo sapiens microtubule-actin
crosslinking factor 1 protein.
Length = 5430
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4556 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4615
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4616 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 4671
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4672 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4731
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4732 VHGDLDLVMNLMDAHKVFQKEL 4753
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4668 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4727
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4728 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4784
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 4785 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 4844
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 4845 EALQSLIDTHKEF 4857
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4340 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4399
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4400 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4457
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4458 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4517
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4518 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4548
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4461 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4519
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4520 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4578
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4579 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4638
Query: 583 FEEDL 597
F++ L
Sbjct: 4639 FQKTL 4643
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3243 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3300
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3301 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3360
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3361 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3420
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3421 KIQQQIIRHKALEEDI 3436
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4125 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4184
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4185 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4242
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4243 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4302
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4303 VELAKHHVLKNDV 4315
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 4775 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 4834
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 4835 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 4892
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 4893 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 4951
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 4952 PQNIDRVKALIAEHQTFMEEM 4972
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4234 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4291
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4292 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4351
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4352 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4411
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4412 EQLDTHMELYSQL 4424
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2701 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2758
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2759 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2818
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2819 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2856
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3569 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3628
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3629 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3686
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3687 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3746
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3747 DQTTAQLQVQKAFSIDI 3763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3356 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3413
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3414 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3473
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3474 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3510
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3132 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3189
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3190 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3249
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3250 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3309
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3310 YKVVKAQIQEQKLLQRLLDDRKA 3332
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2363 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2422
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2423 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2482
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2483 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 2525
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1901 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1960
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1961 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2020
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2021 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2058
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3899 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3958
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3959 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4018
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4019 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4059
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2481 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 2540
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2541 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2596
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2597 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2656
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2657 VKQQLEETSEIRSDL 2671
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2811 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2868
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2869 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2926
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2927 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2956
>AB029290-1|BAA83821.1| 5430|Homo sapiens actin binding protein ABP620
protein.
Length = 5430
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4556 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4615
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4616 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 4671
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4672 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4731
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4732 VHGDLDLVMNLMDAHKVFQKEL 4753
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4668 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4727
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4728 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4784
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 4785 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 4844
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 4845 EALQSLIDTHKEF 4857
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4340 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4399
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4400 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4457
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4458 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4517
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4518 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4548
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4461 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4519
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4520 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4578
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4579 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4638
Query: 583 FEEDL 597
F++ L
Sbjct: 4639 FQKTL 4643
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3243 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3300
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3301 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3360
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3361 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3420
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3421 KIQQQIIRHKALEEDI 3436
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4125 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4184
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4185 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4242
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4243 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4302
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4303 VELAKHHVLKNDV 4315
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 4775 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 4834
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 4835 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 4892
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 4893 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 4951
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 4952 PQNIDRVKALIAEHQTFMEEM 4972
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4234 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4291
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4292 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4351
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4352 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4411
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4412 EQLDTHMELYSQL 4424
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2701 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2758
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2759 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2818
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2819 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2856
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3569 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3628
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3629 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3686
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3687 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3746
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3747 DQTTAQLQVQKAFSIDI 3763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3356 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3413
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3414 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3473
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3474 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3510
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3132 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3189
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3190 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3249
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3250 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3309
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3310 YKVVKAQIQEQKLLQRLLDDRKA 3332
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2363 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2422
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2423 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2482
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2483 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLQPW 2525
Score = 48.4 bits (110), Expect = 2e-05
Identities = 30/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1901 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1960
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1961 DTAASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2020
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S +D++ +LL
Sbjct: 2021 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQDSLESLL 2058
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3899 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3958
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3959 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4018
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4019 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4059
Score = 37.1 bits (82), Expect = 0.054
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2481 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLQPWLMEKELMMGVLGPLS 2540
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2541 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2596
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2597 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2656
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2657 VKQQLEETSEIRSDL 2671
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2811 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2868
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2869 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2926
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2927 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2956
>AB007934-1|BAA32310.3| 4433|Homo sapiens KIAA0465 protein protein.
Length = 4433
Score = 223 bits (545), Expect = 4e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 3559 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 3618
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 3619 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DSQ 3674
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 3675 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 3734
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 3735 VHGDLDLVMNLMDAHKVFQKEL 3756
Score = 99.5 bits (237), Expect = 9e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 3671 EDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 3730
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 3731 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 3787
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 3788 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 3847
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 3848 EALQSLIDTHKEF 3860
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 3343 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 3402
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 3403 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 3460
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 3461 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 3520
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 3521 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 3551
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 3464 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 3522
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 3523 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 3581
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 3582 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 3641
Query: 583 FEEDL 597
F++ L
Sbjct: 3642 FQKTL 3646
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 3128 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 3187
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 3188 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 3245
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 3246 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 3305
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 3306 VELAKHHVLKNDV 3318
Score = 77.4 bits (182), Expect = 4e-14
Identities = 43/196 (21%), Positives = 86/196 (43%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 2355 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 2412
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 2413 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 2472
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 2473 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 2532
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK E++
Sbjct: 2533 KIQQQIIRHKALNEEI 2548
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 3778 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 3837
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 3838 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 3895
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 3896 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 3954
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 3955 PQNIDRVKALIAEHQTFMEEM 3975
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 3237 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 3294
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 3295 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 3354
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 3355 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 3414
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 3415 EQLDTHMELYSQL 3427
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 1813 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 1870
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 1871 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 1930
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 1931 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 1968
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 2572 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 2631
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 2632 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 2689
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 2690 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 2749
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 2750 DQTTAQLQVQKAFSIDI 2766
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/157 (23%), Positives = 78/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 2468 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 2525
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ + + +++ D +K G+ L + + ++ + +K
Sbjct: 2526 PVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIK 2585
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
T++ + + R LE+A + +F+ L W
Sbjct: 2586 TRYADITVTSSKALRTLEQARQLATKFQSTYEELTGW 2622
Score = 50.8 bits (116), Expect = 4e-06
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 1474 KTDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVL 1533
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 1534 KSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWK 1593
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 1594 KIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 1637
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 2244 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 2301
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 2302 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 2361
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 2362 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 2421
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 2422 YKVVKAQIQEQKLLQRLLDDRKA 2444
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1034 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1093
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1094 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1153
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1154 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 1191
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 2902 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 2961
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 2962 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 3021
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 3022 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 3062
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 1593 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 1652
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 1653 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 1708
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 1709 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 1768
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 1769 VKQQLEETSEIRSDL 1783
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 1923 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 1980
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 1981 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2038
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2039 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2068
>AF325341-2|AAL38997.1| 5314|Homo sapiens macrophin 1 isoform 4
protein.
Length = 5314
Score = 223 bits (544), Expect = 6e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 5058 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 5117
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 5118 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DTQ 5173
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 5174 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 5233
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 5234 VHGDLDLVMNLMDAHKVFQKEL 5255
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4842 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4901
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4902 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4959
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4960 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 5019
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 5020 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 5050
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4963 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 5021
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 5022 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 5080
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 5081 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 5140
Query: 583 FEEDL 597
F++ L
Sbjct: 5141 FQKTL 5145
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3745 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3802
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3803 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3862
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3863 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3922
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3923 KIQQQIIRHKALEEDI 3938
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4627 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4686
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4687 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4744
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4745 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4804
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4805 VELAKHHVLKNDV 4817
Score = 79.8 bits (188), Expect = 8e-15
Identities = 41/146 (28%), Positives = 75/146 (51%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 5170 EDTQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 5229
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 5230 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 5286
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEAL 444
+ ++ T+W TVC +V +Q +LE+AL
Sbjct: 5287 LQELSTRWDTVCKLSVSKQSRLEQAL 5312
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4736 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4793
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4794 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4853
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4854 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4913
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4914 EQLDTHMELYSQL 4926
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 3203 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 3260
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 3261 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 3320
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 3321 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 3358
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 4071 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 4130
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 4131 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 4188
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 4189 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 4248
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 4249 DQTTAQLQVQKAFSIDI 4265
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3858 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3915
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3916 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3975
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3976 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 4012
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3634 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3691
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3692 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3751
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3752 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3811
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3812 YKVVKAQIQEQKLLQRLLDDRKA 3834
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2865 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2924
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2925 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2984
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2985 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 3027
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 2403 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 2462
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 2463 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2522
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2523 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2560
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 4401 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 4460
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 4461 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4520
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4521 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4561
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2983 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 3042
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 3043 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 3098
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 3099 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 3158
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 3159 VKQQLEETSEIRSDL 3173
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 3313 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 3370
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 3371 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 3428
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 3429 QNMDAVTEELQAKTGSLEEMTQRLREFQES 3458
>AF325341-1|AAL39000.1| 4631|Homo sapiens macrophin 1 isoform 2
protein.
Length = 4631
Score = 223 bits (544), Expect = 6e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4375 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4434
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4435 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DTQ 4490
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4491 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4550
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4551 VHGDLDLVMNLMDAHKVFQKEL 4572
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4159 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4218
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4219 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4276
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4277 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4336
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4337 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4367
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4280 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4338
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4339 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4397
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4398 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4457
Query: 583 FEEDL 597
F++ L
Sbjct: 4458 FQKTL 4462
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3062 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3119
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3120 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3179
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3180 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3239
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3240 KIQQQIIRHKALEEDI 3255
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 3944 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4003
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4004 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4061
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4062 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4121
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4122 VELAKHHVLKNDV 4134
Score = 79.8 bits (188), Expect = 8e-15
Identities = 41/146 (28%), Positives = 75/146 (51%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4487 EDTQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4546
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4547 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4603
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEAL 444
+ ++ T+W TVC +V +Q +LE+AL
Sbjct: 4604 LQELSTRWDTVCKLSVSKQSRLEQAL 4629
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4053 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4110
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4111 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4170
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4171 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4230
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4231 EQLDTHMELYSQL 4243
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2520 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2577
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2578 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2637
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2638 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2675
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3388 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3447
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3448 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3505
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3506 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3565
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3566 DQTTAQLQVQKAFSIDI 3582
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3175 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3232
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3233 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3292
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3293 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3329
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 2951 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3008
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3009 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3068
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3069 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3128
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3129 YKVVKAQIQEQKLLQRLLDDRKA 3151
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2182 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2241
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2242 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2301
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2302 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 2344
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1720 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1779
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1780 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1839
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1840 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 1877
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3718 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3777
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3778 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 3837
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 3838 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 3878
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2300 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 2359
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2360 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2415
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2416 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2475
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2476 VKQQLEETSEIRSDL 2490
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2630 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2687
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2688 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2745
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2746 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2775
>AF317696-1|AAL09459.1| 5938|Homo sapiens macrophin 1 isoform 4
protein.
Length = 5938
Score = 223 bits (544), Expect = 6e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 5058 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 5117
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 5118 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DTQ 5173
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 5174 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 5233
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 5234 VHGDLDLVMNLMDAHKVFQKEL 5255
Score = 100 bits (239), Expect = 5e-21
Identities = 52/193 (26%), Positives = 96/193 (49%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 5170 EDTQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 5229
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 5230 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 5286
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W + D
Sbjct: 5287 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT 5346
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 5347 EALQSLIDTHKEF 5359
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4842 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4901
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4902 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4959
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4960 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 5019
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 5020 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 5050
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4963 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 5021
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 5022 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 5080
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 5081 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 5140
Query: 583 FEEDL 597
F++ L
Sbjct: 5141 FQKTL 5145
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3745 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3802
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3803 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3862
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3863 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3922
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3923 KIQQQIIRHKALEEDI 3938
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4627 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4686
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4687 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4744
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4745 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4804
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4805 VELAKHHVLKNDV 4817
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+ L
Sbjct: 5277 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTL 5336
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 5337 RFRG--ALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 5394
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 5395 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 5453
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 5454 PQNIDRVKALIAEHQTFMEEM 5474
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4736 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4793
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4794 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4853
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4854 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4913
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4914 EQLDTHMELYSQL 4926
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 3203 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 3260
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 3261 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 3320
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 3321 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 3358
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 4071 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 4130
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 4131 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 4188
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 4189 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 4248
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 4249 DQTTAQLQVQKAFSIDI 4265
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3858 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3915
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3916 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3975
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3976 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 4012
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3634 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3691
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3692 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3751
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3752 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3811
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3812 YKVVKAQIQEQKLLQRLLDDRKA 3834
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 1/163 (0%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2865 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLK 2924
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKT 363
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2925 SMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKK 2984
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2985 IQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 3027
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 2403 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 2462
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 2463 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 2522
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 2523 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2560
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 4401 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 4460
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 4461 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 4520
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 4521 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4561
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2983 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 3042
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 3043 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 3098
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 3099 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 3158
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 3159 VKQQLEETSEIRSDL 3173
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 3313 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 3370
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 3371 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 3428
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 3429 QNMDAVTEELQAKTGSLEEMTQRLREFQES 3458
>AF141968-1|AAF06360.1| 5373|Homo sapiens trabeculin-alpha protein.
Length = 5373
Score = 223 bits (544), Expect = 6e-58
Identities = 109/202 (53%), Positives = 141/202 (69%), Gaps = 3/202 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
QKQDV+LIKNLLVSVQ RWE+VV +S ER R+LD K AK+F + W L++WL + E
Sbjct: 4500 QKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESH 4559
Query: 181 LDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA--PKGDEN 351
LD SE + NDPDKIK +L+KH+EFQK L KQP YD T++TG+ LK+K P+ D
Sbjct: 4560 LD---SELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPE-DTQ 4615
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAP 531
L + +++ KW TVC K+V+RQ KLEEALL+SGQF DA+ AL+DW D P
Sbjct: 4616 KLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQP 4675
Query: 532 VHGDLDTVMALIEQHKQFEEDL 597
VHGDLD VM L++ HK F+++L
Sbjct: 4676 VHGDLDLVMNLMDAHKVFQKEL 4697
Score = 97.5 bits (232), Expect = 4e-20
Identities = 53/193 (27%), Positives = 97/193 (50%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+D + N L V+ +W+ V KS ER L+ + +F D L++WL + E QL
Sbjct: 4612 EDTQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLA 4671
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
+ + D D + ++ H+ FQK L + + ++G+ L + + + D +K
Sbjct: 4672 E--DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENS-RDDTTWVKGQ 4728
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ T+W TVC +V +Q +LE+AL + F+D + LL+W A + D
Sbjct: 4729 LQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQLRFRGA-LPDDT 4787
Query: 547 DTVMALIEQHKQF 585
+ + +LI+ HK+F
Sbjct: 4788 EALQSLIDTHKEF 4800
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +++ L ++ WE V+ K+ ER + L ++A+ F + + L E QL
Sbjct: 4284 DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSA 4343
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK-HLKDKAPKGDENPLKTM 366
S+ T P+ +++L+ H E L +K+ Y+ + G+ L + G + +
Sbjct: 4344 --SKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQS 4401
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ KW V SK +R+ KLEEAL + +F++++ ++W +P L
Sbjct: 4402 VALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLIL 4461
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDRPG 645
+TV++ IE+HK F +++ R D + D+ G
Sbjct: 4462 NTVLSQIEEHKVFANEVNAHR--DQIIELDQTG 4492
Score = 83.4 bits (197), Expect = 6e-16
Identities = 42/185 (22%), Positives = 89/185 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ +W V SK ER L+ A EF + +NWL E+ L+ + + + +
Sbjct: 4405 LEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNT- 4463
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ +H+ F + + + +TG LK + K D +K ++ ++++W V
Sbjct: 4464 -VLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVV 4522
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
++++R R L++A + QF +A L+DW + + + D D + + +HK+
Sbjct: 4523 QRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKE 4582
Query: 583 FEEDL 597
F++ L
Sbjct: 4583 FQKTL 4587
Score = 81.0 bits (191), Expect = 3e-15
Identities = 45/196 (22%), Positives = 87/196 (44%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
DV +++ + + RW + K A+R L +F D L++WL +TEE +
Sbjct: 3187 DVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELI-- 3244
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +K ++ + + Q+ L ++ D+ G + A D + +
Sbjct: 3245 ANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQL 3304
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLD 549
++++WT + SKA RQ++LE+ L+ + QF + + D+ PV
Sbjct: 3305 ESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA 3364
Query: 550 TVMALIEQHKQFEEDL 597
+ I +HK EED+
Sbjct: 3365 KIQQQIIRHKALEEDI 3380
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + + + WE + ER L+ + A ++ D + +WL+ T +L +
Sbjct: 4069 VRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPV 4128
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP-KGDENPLKTMITDM 378
T D + +K +LN+ +EF+ + +Q + G+ + KA + D + ++ +T++
Sbjct: 4129 GT--DLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTEL 4186
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
K W + K RQ KLE ALL GQF+ A+ L+ W + P+ GD +
Sbjct: 4187 KHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIE 4246
Query: 559 ALIEQHKQFEEDL 597
+ +H + D+
Sbjct: 4247 VELAKHHVLKNDV 4259
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/193 (23%), Positives = 76/193 (39%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I+ L ++H WE + K A R L+ +F LM+WL TEE LD
Sbjct: 4178 IIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDA--Q 4235
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
DP I+ L KH + + + Q + K G L + + D + L++ + M
Sbjct: 4236 RPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAM 4295
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
W +V K +R+++L+ L + F + L P G +T
Sbjct: 4296 NQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAR 4355
Query: 559 ALIEQHKQFEEDL 597
++ H + L
Sbjct: 4356 EQLDTHMELYSQL 4368
Score = 70.9 bits (166), Expect = 4e-12
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
+ D +K L + RW+ V S + L+ K+A+ F D + L+ WL+E E+
Sbjct: 4719 RDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQLR 4778
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKT 363
+ A +D + ++ ++ H+EF K + K+ + + G+ + +K
Sbjct: 4779 FR---GALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKH 4835
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSALLDWXXXXXXXXEGDAPV 534
IT ++ ++ V + A Q++LE A L+ + + + + A + W + + P+
Sbjct: 4836 WITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQE-PI 4894
Query: 535 HGDLDTVMALIEQHKQFEEDL 597
++D V ALI +H+ F E++
Sbjct: 4895 PQNIDRVKALIAEHQTFMEEM 4915
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L +V + + +A+R L ++F M++ L WL++ + Q Q +
Sbjct: 2645 LKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQ--QAKNC 2702
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDM 378
++++ +L ++ EFQK+L +Y++ + G+ L P G+E L+ + ++
Sbjct: 2703 PISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVEL 2762
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
K W + K DRQ +L++ + + +++ + L+ W
Sbjct: 2763 KNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPW 2800
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/197 (20%), Positives = 84/197 (42%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
++V+LI+ L ++ R+ + S++ R L+ + A +F + L WL E EE+L
Sbjct: 3513 EEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELA 3572
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
++ ++I Q + +E +K + + D + + L + P L +
Sbjct: 3573 TSGGQSPTG--EQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKL 3630
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
++D ++ V R +++ A+ S Q++ A A L W P+ +
Sbjct: 3631 VSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQ 3690
Query: 547 DTVMALIEQHKQFEEDL 597
D A ++ K F D+
Sbjct: 3691 DQTTAQLQVQKAFSIDI 3707
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/157 (22%), Positives = 77/157 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I L S++ RW ++SK+A R + L+ AK+F + + ++L+ TE++L NSE
Sbjct: 3300 ITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKL--ANSE 3357
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
KI+Q++ +H+ ++ + + +K G+ L ++ L I ++
Sbjct: 3358 PVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSEKIDSLQ 3417
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + + L++AL + F + +L+W
Sbjct: 3418 ARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNW 3454
Score = 50.8 bits (116), Expect = 4e-06
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D+ I+ + V ++E++ ER +L +E N+++ WL EE L
Sbjct: 2306 KTDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVL 2365
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+++ ++ + +K + ++ F L P + L P E K
Sbjct: 2366 KSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWK 2425
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ ++W V RQR+LEE+ + F+ A S L W
Sbjct: 2426 KIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPW 2469
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ +K L ++ + ++ + R L+ ++F L + EE +
Sbjct: 3076 DLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEA--E 3133
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKG-DENPLKT 363
+ + I Q+L + FQK Q G+ L A K D L+
Sbjct: 3134 ALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEH 3193
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD 543
+ ++ +W T+ K R +L+EALL+ G+F+DA+ LL W P +
Sbjct: 3194 DMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 3253
Query: 544 LDTVMALIEQHKQFEEDLHFARA 612
V A I++ K + L +A
Sbjct: 3254 YKVVKAQIQEQKLLQRLLDDRKA 3276
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1866 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1925
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1926 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1985
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1986 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 2023
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/161 (16%), Positives = 74/161 (45%), Gaps = 5/161 (3%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+++ ++ + ++ + +R ALD ++ + ++ + + L E +L
Sbjct: 3843 MVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRM 3902
Query: 199 EATVN-DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKT 363
+ + DKI++ ++ ++ L QP+++ + G+ L ++ D++ ++
Sbjct: 3903 PPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQD 3962
Query: 364 MITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ M W + ++A +R+ K + L + +F M+ALL
Sbjct: 3963 KLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALL 4003
Score = 36.7 bits (81), Expect = 0.072
Identities = 32/195 (16%), Positives = 75/195 (38%), Gaps = 4/195 (2%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K + + RWER + R R L+ F + L WL E E + L +
Sbjct: 2425 KKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLS 2484
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD----ENPLKTMIT 372
DP+ + + + + K +++ ++ + + + GD + ++ +
Sbjct: 2485 I--DPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGI--LTGPGDVSLSTSQVQKELQ 2540
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDT 552
+ KW + K R ++++A++ S Q+++ + L + + + +
Sbjct: 2541 SINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEA 2600
Query: 553 VMALIEQHKQFEEDL 597
V +E+ + DL
Sbjct: 2601 VKQQLEETSEIRSDL 2615
Score = 36.7 bits (81), Expect = 0.072
Identities = 23/150 (15%), Positives = 69/150 (46%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N LV +++ WE + K+A+R L ++A+++ +L+ W+ + + ++ +L
Sbjct: 2755 LQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELR-- 2812
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
DP +++ L + + + ++ ++ + + + + + DE+ ++ +
Sbjct: 2813 -VTLDPVQLESSLLRSKAMLNEVEKRRSLLEI-LNSAADILINSSEADEDGIRDEKAGIN 2870
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
V + + LEE +F+++
Sbjct: 2871 QNMDAVTEELQAKTGSLEEMTQRLREFQES 2900
>AK025142-1|BAB15077.1| 167|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21489 fis, clone COL05450. ).
Length = 167
Score = 155 bits (377), Expect = 1e-37
Identities = 74/145 (51%), Positives = 99/145 (68%), Gaps = 2/145 (1%)
Frame = +1
Query: 151 MNWLNETEEQLDQLNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
M WL E+E+ LD SE + NDPDKIK +L +H+EFQK+L +K YD T +TG+ LK+
Sbjct: 1 MEWLEESEKSLD---SELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKE 57
Query: 328 KAPKGDEN-PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXX 504
K D+N L M+++++ KW T+C K+V+RQ KLEEALL+SGQF DA+ AL+DW
Sbjct: 58 KTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRV 117
Query: 505 XXXXEGDAPVHGDLDTVMALIEQHK 579
D PVHGD+D VM LI+ HK
Sbjct: 118 EPQLAEDQPVHGDIDLVMNLIDNHK 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 19/81 (23%), Positives = 40/81 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + + ++L ++ +W+ + KS ER L+ + +F+D L++WL E QL +
Sbjct: 64 DNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAE 123
Query: 190 LNSEATVNDPDKIKQRLNKHR 252
+ D D + ++ H+
Sbjct: 124 --DQPVHGDIDLVMNLIDNHK 142
>AK055189-1|BAB70870.1| 1174|Homo sapiens protein ( Homo sapiens cDNA
FLJ30627 fis, clone CTONG2001955, moderately similar to
Homo sapiens mRNA for actin binding protein ABP620. ).
Length = 1174
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/188 (21%), Positives = 83/188 (44%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L V RW+ + K A+R L F D +L++W+ +TEE + N +
Sbjct: 513 LDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELV--ANQKPPSA 570
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
+ +K ++ + + Q+ L ++ ++ + G+ + A D+ + ++ + ++W
Sbjct: 571 EFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWE 630
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQ 573
+ +KA R R+LE + + QF + + L +W P+ + I Q
Sbjct: 631 ALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQ 690
Query: 574 HKQFEEDL 597
HK E+D+
Sbjct: 691 HKALEDDI 698
Score = 64.9 bits (151), Expect = 2e-10
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D++ IK L ++ + +++ ++ R ++ K +EF L + EE +
Sbjct: 394 DLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEE- 452
Query: 190 LNSEATVN-DPDKIKQRLNKHREFQKA-LASKQPAYDLTMKTGKHLKDKAPKGDENP-LK 360
S+ V + + I Q+LN + FQK + Q G+ L A K L+
Sbjct: 453 --SQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLE 510
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ D+ +W T+ K R +L+EALL+ G+F+DA+ +LL W P
Sbjct: 511 HDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSA 570
Query: 541 DLDTVMALIEQHK 579
+ V A I++ K
Sbjct: 571 EFKVVKAQIQEQK 583
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/161 (20%), Positives = 76/161 (47%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D + I L + RWE +++K+ R R L+ A++F + L WL E++L
Sbjct: 614 DKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL-- 671
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+N E K+++++ +H+ + + + + G+ LK + + D++ +++ +
Sbjct: 672 VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKL 731
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + + K+ R L++AL + F + L++W
Sbjct: 732 DFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNW 772
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/105 (24%), Positives = 52/105 (49%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 1054 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 1113
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP 336
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P
Sbjct: 1114 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP 1156
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 945 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 1004
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 1005 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 1062
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 1063 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 1122
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 1123 QQEEHRQLRE 1132
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
++D ++++ L Q + + KS R+ L AK F + LMNWLNE ++L
Sbjct: 721 REDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKL 780
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLK 360
+L+ + + + ++ ++ R Q+ + ++ D + G L K GDE ++
Sbjct: 781 SKLSVQD--YSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQ 837
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +K ++ + + D + LE+AL + + L W
Sbjct: 838 DKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTW 881
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/123 (20%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ W+ + ER L ++A ++ + L W+++ + L+++
Sbjct: 76 LNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIK---FCL 132
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK-----DKAPKGDENPLKTMITDM 378
DP + + + K + QK + +L T L DK DEN DM
Sbjct: 133 DPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDM 192
Query: 379 KTK 387
T+
Sbjct: 193 VTE 195
>AK096713-1|BAC04848.1| 990|Homo sapiens protein ( Homo sapiens cDNA
FLJ39394 fis, clone PLACE6007925, moderately similar to
Homo sapiens mRNA for actin binding protein ABP620. ).
Length = 990
Score = 68.9 bits (161), Expect = 1e-11
Identities = 44/182 (24%), Positives = 84/182 (46%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE + + ER L + A++F +L+ + +T++ + L DP +KQ
Sbjct: 561 WENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGI--DPSVVKQ 618
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAV 414
+ ++ + Q D+ + G L + D+ +K I ++ + W ++
Sbjct: 619 QQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWK 678
Query: 415 DRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEED 594
DR KLEEA+ + Q++D + A+ DW +P+ DL+TV IE+ KQF+ +
Sbjct: 679 DRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSE 738
Query: 595 LH 600
+
Sbjct: 739 AY 740
Score = 68.9 bits (161), Expect = 1e-11
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 1/197 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D ++K + + W+ + +R L+ + A ++ D + +W++ +L
Sbjct: 655 DKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLAS 714
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYD-LTMKTGKHLKDKAPKGDENPLKTM 366
++ T D + +KQ++ + ++F+ +Q + L + LK + D++ ++
Sbjct: 715 MSPIGT--DLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDP 772
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++K W ++ + ++RQ KLE ALL GQF+ A+ LL W PV GD
Sbjct: 773 LMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDP 832
Query: 547 DTVMALIEQHKQFEEDL 597
+ + +H + D+
Sbjct: 833 KAIEIELAKHHVLQNDV 849
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/109 (31%), Positives = 56/109 (51%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++N L + RW+ V+ K+ +R + LD ++AK F +L WL +TE L L S+
Sbjct: 878 LQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHL--LASK 935
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE 348
P+ K++LN H E A +K+ Y M+ G+ + + PK E
Sbjct: 936 PLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAE 984
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/192 (20%), Positives = 85/192 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L V ++ + ++ER L+ +F + + L WL ET+ + QL +
Sbjct: 329 MKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAP 388
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A + + ++Q+ +HR+ ++ +A +P D KTG L + +P G+ ++
Sbjct: 389 AL--EYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSP-GEGFSIQEKYVAAD 445
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
T ++ + R L+EA+ S QF D + +L+ + +++ +
Sbjct: 446 TLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEEIKE 505
Query: 562 LIEQHKQFEEDL 597
I ++K D+
Sbjct: 506 QISENKNVSVDM 517
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/194 (19%), Positives = 77/194 (39%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D +++ L+ ++ W+ + + R L+ +F + L+ WL TE
Sbjct: 762 EESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGL 821
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L + + DP I+ L KH Q + + Q + K G L + + + + L+
Sbjct: 822 LSE--QKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQ 879
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHG 540
+ + +W V K R+++L+ AL + F + L W P+ G
Sbjct: 880 NKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGG 939
Query: 541 DLDTVMALIEQHKQ 582
+T + H +
Sbjct: 940 LPETAKEQLNVHME 953
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/190 (16%), Positives = 74/190 (38%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ ++ R+ V ++ +D +++F + ++W+ ETE++L L
Sbjct: 220 LEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDI 279
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ D+ +L + F + + D +K+G + + ++ +K + +
Sbjct: 280 RL--EQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVL 337
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMA 561
+ T+C +R +LE A QF + L W + +T+
Sbjct: 338 KNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQ 397
Query: 562 LIEQHKQFEE 591
E+H+Q E
Sbjct: 398 QQEEHRQLRE 407
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 1/144 (0%)
Frame = +1
Query: 64 VVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLN 243
+ KS R+ L AK F + LMNWLNE ++L +L+ + + + ++ +
Sbjct: 16 IQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQD--YSTEGLWKQQS 73
Query: 244 KHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE-NPLKTMITDMKTKWTTVCSKAVDR 420
+ R Q+ + ++ D + G L K GDE ++ + +K ++ + + D
Sbjct: 74 ELRVLQEDILLRKQNVDQALLNGLELL-KQTTGDEVLIIQDKLEAIKARYKDITKLSTDV 132
Query: 421 QRKLEEALLYSGQFKDAMSALLDW 492
+ LE+AL + + L W
Sbjct: 133 AKTLEQALQLARRLHSTHEELCTW 156
>X69086-1|CAA48829.1| 3433|Homo sapiens utrophin (dystrophin related
protein) protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>AL590704-1|CAI10894.1| 3433|Homo sapiens utrophin protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>AL590488-1|CAI16497.1| 3433|Homo sapiens utrophin protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>AL513475-1|CAI13032.1| 3433|Homo sapiens utrophin protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>AL513184-1|CAI40502.1| 3433|Homo sapiens utrophin protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>AL357149-1|CAI40388.1| 3433|Homo sapiens utrophin protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>AL024474-2|CAI23353.1| 3433|Homo sapiens utrophin protein.
Length = 3433
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/161 (22%), Positives = 80/161 (49%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
+ I I++ L + +W+R+ ++R D +E ++F N+L W+ E EE L
Sbjct: 1942 EAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELL-- 1999
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+++ A D K R+++ +E + ++S QP++ +TG + K + D + LK +
Sbjct: 2000 VDTCAPGGSLDLEKARIHQ-QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKL 2058
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + ++ DRQ +L+ +++ + ++ W
Sbjct: 2059 AGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICW 2099
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD 327
++ WL E+ + + + +D +++K + H F L + Q + ++ G L
Sbjct: 321 VLTWLLSAEDTFQEQDDIS--DDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378
Query: 328 KAPKGDENP--LKTMITDMKTKWTTVCSKAVDRQRKLEEALL-YSGQFKDAMSALLDWXX 498
+ DE ++ +T + +W + +++DRQ +L + L+ + +SA L
Sbjct: 379 QGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTE 438
Query: 499 XXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
E P+ D+ ++ L+E+HK + DL
Sbjct: 439 ERIQKME-TCPLDDDVKSLQKLLEEHKSLQSDL 470
Score = 44.0 bits (99), Expect = 5e-04
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + RWE + +S +R L E ++ L WL TEE++ ++ +
Sbjct: 390 IQEQMTLLNARWEALRVESMDRQSRLHDVLMELQK--KQLQQLSAWLTLTEERIQKMETC 447
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+D +++ L +H+ Q L ++Q + + + + + L+ + +
Sbjct: 448 PLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLG 507
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+WT VC +R +L+E + + + L W
Sbjct: 508 ERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAW 544
Score = 44.0 bits (99), Expect = 5e-04
Identities = 21/93 (22%), Positives = 46/93 (49%)
Frame = +1
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
DPD I+ L+K + K L+ + + +KTG+H+ K + + +T +K +
Sbjct: 1467 DPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYN 1526
Query: 394 TVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ ++ + ++ LE A + + K ++L +W
Sbjct: 1527 DLGAQVTEGKQDLERASQLARKMKKEAASLSEW 1559
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/197 (15%), Positives = 74/197 (37%), Gaps = 5/197 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQL--- 192
+K ++ W + A+R AL+ ++ + N + W+ E E ++ L
Sbjct: 2413 VKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDA 2472
Query: 193 -NSEATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTM 366
+ E + D ++ + ++ Q + + + + K +K + L+
Sbjct: 2473 SHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHR 2532
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ DM +W + +K+ + LE + + ++ L+ W + P+ GD+
Sbjct: 2533 LDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDV 2592
Query: 547 DTVMALIEQHKQFEEDL 597
+ + K +L
Sbjct: 2593 PALQLQYDHCKALRREL 2609
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/184 (18%), Positives = 69/184 (37%), Gaps = 2/184 (1%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFK--EAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDK 225
R++ V +R + L++ K + + L + LN++E + S +ND K
Sbjct: 885 RYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQV--SLNVLNDLAK 942
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+++ L + + + L +++PA + K L+ E K D++ KW +
Sbjct: 943 VEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKV 1002
Query: 406 KAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQF 585
LEE L F+ + + W GD + ++Q F
Sbjct: 1003 LVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAF 1062
Query: 586 EEDL 597
++
Sbjct: 1063 VNEI 1066
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/131 (16%), Positives = 53/131 (40%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K L + RW+ +V++ +R L K+ ++ + ++ WL + E + +
Sbjct: 2050 DGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQK 2109
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ + +++ L + E +L M + K L P+ D+ + +
Sbjct: 2110 RSTTELGENLQELRD-LTQEMEVHAEKLKWLNRTELEMLSDKSL--SLPERDK--ISESL 2164
Query: 370 TDMKTKWTTVC 402
+ W +C
Sbjct: 2165 RTVNMTWNKIC 2175
>BX537837-1|CAD97849.1| 1523|Homo sapiens hypothetical protein
protein.
Length = 1523
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 1146 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 1205
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 1206 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 1264
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 1265 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 1323
Query: 592 DLH 600
H
Sbjct: 1324 IKH 1326
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 263 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 320
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 321 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 380
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 381 KSASMRLEEQKKKL 394
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 472 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 531
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 532 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 585
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 586 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 626
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 581 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 640
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 641 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 699
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 700 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 740
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 701 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 760
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 761 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 818
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 819 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 876
Query: 580 QFEEDL 597
F++++
Sbjct: 877 AFQQEI 882
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 804 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 863
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 864 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 919
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 920 RYCQEVFGRVERYHKKL 936
>BC090927-1|AAH90927.1| 997|Homo sapiens SYNE1 protein protein.
Length = 997
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 708 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 767
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 768 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 826
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 827 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 885
Query: 592 DLH 600
H
Sbjct: 886 IKH 888
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 34 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 93
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 94 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 147
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 148 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 188
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 143 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 202
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 203 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 261
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 262 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 302
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 263 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 322
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 323 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 380
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 381 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 438
Query: 580 QFEEDL 597
F++++
Sbjct: 439 AFQQEI 444
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 366 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 425
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 426 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 481
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 482 RYCQEVFGRVERYHKKL 498
>AY184206-1|AAO27774.1| 3212|Homo sapiens nesprin-1 beta 2 protein.
Length = 3212
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2835 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 2894
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 2895 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 2953
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 2954 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 3012
Query: 592 DLH 600
H
Sbjct: 3013 IKH 3015
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 1952 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 2009
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 2010 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 2069
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 2070 KSASMRLEEQKKKL 2083
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 2161 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 2220
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 2221 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2274
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2275 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2315
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 2270 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2329
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2330 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2388
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2389 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2429
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2390 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2449
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2450 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2507
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2508 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2565
Query: 580 QFEEDL 597
F++++
Sbjct: 2566 AFQQEI 2571
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 1191 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 1250
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 1251 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1309
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1310 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1337
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2493 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2552
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2553 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2608
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2609 RYCQEVFGRVERYHKKL 2625
>AY184203-1|AAO27771.1| 977|Homo sapiens nesprin-1 alpha 2 protein.
Length = 977
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 600 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 659
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 660 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 718
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 719 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 777
Query: 592 DLH 600
H
Sbjct: 778 IKH 780
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 132 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 191
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 192 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 249
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 250 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 307
Query: 580 QFEEDL 597
F++++
Sbjct: 308 AFQQEI 313
Score = 37.5 bits (83), Expect = 0.041
Identities = 26/140 (18%), Positives = 60/140 (42%), Gaps = 4/140 (2%)
Frame = +1
Query: 85 RTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQK 264
R + L ++ ++L WL E +L + + N ++I+++LN+ +E Q+
Sbjct: 33 RVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNS-EEIQRKLNEQQELQR 91
Query: 265 ALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMITDMKTKWTTVCSKAVDRQRKL 432
+ + + L A + + ++ ++ +W +C+ +++R+ K+
Sbjct: 92 DIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKI 151
Query: 433 EEALLYSGQFKDAMSALLDW 492
EE +F D S DW
Sbjct: 152 EETWRLWQKFLDDYSRFEDW 171
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 235 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 294
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 295 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 350
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 351 RYCQEVFGRVERYHKKL 367
>AY061756-1|AAL33799.1| 982|Homo sapiens nesprin-1 alpha protein.
Length = 982
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 605 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 664
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 665 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 723
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 724 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 782
Query: 592 DLH 600
H
Sbjct: 783 IKH 785
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 17 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 76
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 77 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 135
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 136 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 176
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 137 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 196
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 197 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 254
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 255 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 312
Query: 580 QFEEDL 597
F++++
Sbjct: 313 AFQQEI 318
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 240 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 299
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 300 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 355
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 356 RYCQEVFGRVERYHKKL 372
>AY061755-1|AAL33798.1| 3321|Homo sapiens nesprin-1 beta protein.
Length = 3321
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2944 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 3003
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 3004 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 3062
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 3063 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 3121
Query: 592 DLH 600
H
Sbjct: 3122 IKH 3124
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 2061 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 2118
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 2119 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 2178
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 2179 KSASMRLEEQKKKL 2192
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 2270 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 2329
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 2330 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2383
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2384 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2424
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 2379 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2438
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2439 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2497
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2498 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2538
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2499 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2558
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2559 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2616
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2617 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2674
Query: 580 QFEEDL 597
F++++
Sbjct: 2675 AFQQEI 2680
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 1300 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 1359
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 1360 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1418
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1419 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1446
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2602 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2661
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2662 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2717
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2718 RYCQEVFGRVERYHKKL 2734
>AL450401-4|CAI40730.1| 2963|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 2963
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2586 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 2645
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 2646 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 2704
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 2705 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 2763
Query: 592 DLH 600
H
Sbjct: 2764 IKH 2766
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 1680 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 1737
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 1738 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 1797
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 1798 KSASMRLEEQKKKL 1811
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 1889 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 1948
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 1949 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2002
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2003 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2043
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 1998 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2057
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2058 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2116
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2117 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2157
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2118 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2177
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2178 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2235
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2236 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2293
Query: 580 QFEEDL 597
F++++
Sbjct: 2294 AFQQEI 2299
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 919 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 978
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 979 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1037
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1038 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1065
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2221 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2280
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2281 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2336
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2337 RYCQEVFGRVERYHKKL 2353
>AL450401-3|CAI40729.1| 3321|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 3321
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2944 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 3003
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 3004 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 3062
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 3063 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 3121
Query: 592 DLH 600
H
Sbjct: 3122 IKH 3124
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 2061 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 2118
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 2119 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 2178
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 2179 KSASMRLEEQKKKL 2192
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 2270 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 2329
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 2330 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2383
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2384 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2424
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 2379 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2438
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2439 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2497
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2498 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2538
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2499 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2558
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2559 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2616
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2617 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2674
Query: 580 QFEEDL 597
F++++
Sbjct: 2675 AFQQEI 2680
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 1300 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 1359
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 1360 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1418
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1419 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1446
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2602 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2661
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2662 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2717
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2718 RYCQEVFGRVERYHKKL 2734
>AL450401-2|CAI40728.1| 982|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 982
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 605 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 664
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 665 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 723
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 724 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 782
Query: 592 DLH 600
H
Sbjct: 783 IKH 785
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 17 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 76
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 77 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 135
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 136 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 176
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 137 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 196
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 197 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 254
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 255 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 312
Query: 580 QFEEDL 597
F++++
Sbjct: 313 AFQQEI 318
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 240 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 299
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 300 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 355
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 356 RYCQEVFGRVERYHKKL 372
>AL450401-1|CAI40727.1| 952|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 952
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 575 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 634
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 635 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 693
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 694 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 752
Query: 592 DLH 600
H
Sbjct: 753 IKH 755
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 130 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 189
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 190 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 247
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 248 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 305
Query: 580 QFEEDL 597
F++++
Sbjct: 306 AFQQEI 311
Score = 37.5 bits (83), Expect = 0.041
Identities = 26/140 (18%), Positives = 60/140 (42%), Gaps = 4/140 (2%)
Frame = +1
Query: 85 RTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQK 264
R + L ++ ++L WL E +L + + N ++I+++LN+ +E Q+
Sbjct: 31 RVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNS-EEIQRKLNEQQELQR 89
Query: 265 ALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMITDMKTKWTTVCSKAVDRQRKL 432
+ + + L A + + ++ ++ +W +C+ +++R+ K+
Sbjct: 90 DIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKI 149
Query: 433 EEALLYSGQFKDAMSALLDW 492
EE +F D S DW
Sbjct: 150 EETWRLWQKFLDDYSRFEDW 169
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 233 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 292
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 293 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 348
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 349 RYCQEVFGRVERYHKKL 365
>AL357081-1|CAI41322.1| 3321|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 3321
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2944 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 3003
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 3004 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 3062
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 3063 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 3121
Query: 592 DLH 600
H
Sbjct: 3122 IKH 3124
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 2061 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 2118
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 2119 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 2178
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 2179 KSASMRLEEQKKKL 2192
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 2270 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 2329
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 2330 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2383
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2384 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2424
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 2379 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2438
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2439 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2497
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2498 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2538
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2499 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2558
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2559 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2616
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2617 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2674
Query: 580 QFEEDL 597
F++++
Sbjct: 2675 AFQQEI 2680
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 1300 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 1359
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 1360 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1418
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1419 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1446
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2602 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2661
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2662 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2717
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2718 RYCQEVFGRVERYHKKL 2734
>AL138832-5|CAI42787.1| 2963|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 2963
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2586 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 2645
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 2646 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 2704
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 2705 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 2763
Query: 592 DLH 600
H
Sbjct: 2764 IKH 2766
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 1680 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 1737
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 1738 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 1797
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 1798 KSASMRLEEQKKKL 1811
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 1889 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 1948
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 1949 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2002
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2003 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2043
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 1998 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2057
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2058 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2116
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2117 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2157
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2118 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2177
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2178 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2235
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2236 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2293
Query: 580 QFEEDL 597
F++++
Sbjct: 2294 AFQQEI 2299
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 919 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 978
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 979 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1037
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1038 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1065
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2221 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2280
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2281 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2336
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2337 RYCQEVFGRVERYHKKL 2353
>AL138832-4|CAI42786.1| 3321|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 3321
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2944 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 3003
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 3004 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 3062
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 3063 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 3121
Query: 592 DLH 600
H
Sbjct: 3122 IKH 3124
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 2061 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 2118
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 2119 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 2178
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 2179 KSASMRLEEQKKKL 2192
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 2270 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 2329
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 2330 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2383
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2384 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2424
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 2379 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2438
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2439 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2497
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2498 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2538
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2499 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2558
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2559 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2616
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2617 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2674
Query: 580 QFEEDL 597
F++++
Sbjct: 2675 AFQQEI 2680
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 1300 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 1359
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 1360 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1418
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1419 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1446
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2602 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2661
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2662 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2717
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2718 RYCQEVFGRVERYHKKL 2734
>AL138832-3|CAI42785.1| 982|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 982
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 605 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 664
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 665 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 723
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 724 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 782
Query: 592 DLH 600
H
Sbjct: 783 IKH 785
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 17 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 76
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 77 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 135
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 136 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 176
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 137 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 196
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 197 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 254
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 255 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 312
Query: 580 QFEEDL 597
F++++
Sbjct: 313 AFQQEI 318
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 240 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 299
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 300 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 355
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 356 RYCQEVFGRVERYHKKL 372
>AL138832-2|CAI42784.1| 952|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 952
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 575 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 634
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 635 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 693
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 694 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 752
Query: 592 DLH 600
H
Sbjct: 753 IKH 755
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 130 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 189
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 190 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 247
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 248 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 305
Query: 580 QFEEDL 597
F++++
Sbjct: 306 AFQQEI 311
Score = 37.5 bits (83), Expect = 0.041
Identities = 26/140 (18%), Positives = 60/140 (42%), Gaps = 4/140 (2%)
Frame = +1
Query: 85 RTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQK 264
R + L ++ ++L WL E +L + + N ++I+++LN+ +E Q+
Sbjct: 31 RVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNS-EEIQRKLNEQQELQR 89
Query: 265 ALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMITDMKTKWTTVCSKAVDRQRKL 432
+ + + L A + + ++ ++ +W +C+ +++R+ K+
Sbjct: 90 DIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKI 149
Query: 433 EEALLYSGQFKDAMSALLDW 492
EE +F D S DW
Sbjct: 150 EETWRLWQKFLDDYSRFEDW 169
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 233 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 292
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 293 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 348
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 349 RYCQEVFGRVERYHKKL 365
>AL078582-5|CAI42287.1| 2963|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 2963
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2586 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 2645
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 2646 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 2704
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 2705 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 2763
Query: 592 DLH 600
H
Sbjct: 2764 IKH 2766
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 1680 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 1737
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 1738 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 1797
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 1798 KSASMRLEEQKKKL 1811
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 1889 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 1948
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 1949 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2002
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2003 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2043
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 1998 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2057
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2058 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2116
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2117 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2157
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2118 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2177
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2178 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2235
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2236 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2293
Query: 580 QFEEDL 597
F++++
Sbjct: 2294 AFQQEI 2299
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 919 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 978
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 979 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1037
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1038 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1065
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2221 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2280
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2281 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2336
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2337 RYCQEVFGRVERYHKKL 2353
>AL078582-3|CAI42284.1| 3321|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 3321
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 2944 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 3003
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 3004 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 3062
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 3063 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 3121
Query: 592 DLH 600
H
Sbjct: 3122 IKH 3124
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 2061 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 2118
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 2119 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 2178
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 2179 KSASMRLEEQKKKL 2192
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 2270 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 2329
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 2330 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 2383
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 2384 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 2424
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 2379 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 2438
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 2439 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 2497
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2498 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 2538
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 2499 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 2558
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 2559 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 2616
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 2617 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 2674
Query: 580 QFEEDL 597
F++++
Sbjct: 2675 AFQQEI 2680
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 1300 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 1359
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 1360 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 1418
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 1419 IPAVQEKLHQLQMDKLPSRHAISEVMSW 1446
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 2602 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 2661
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 2662 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 2717
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 2718 RYCQEVFGRVERYHKKL 2734
>AL078582-2|CAI42283.1| 982|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 982
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 605 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 664
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 665 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 723
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 724 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 782
Query: 592 DLH 600
H
Sbjct: 783 IKH 785
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 17 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 76
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 77 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 135
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 136 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 176
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 137 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 196
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 197 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 254
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 255 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 312
Query: 580 QFEEDL 597
F++++
Sbjct: 313 AFQQEI 318
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 240 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 299
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 300 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 355
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 356 RYCQEVFGRVERYHKKL 372
>AL078582-1|CAI42282.1| 952|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 952
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 575 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 634
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 635 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 693
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 694 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 752
Query: 592 DLH 600
H
Sbjct: 753 IKH 755
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 130 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 189
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 190 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 247
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 248 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 305
Query: 580 QFEEDL 597
F++++
Sbjct: 306 AFQQEI 311
Score = 37.5 bits (83), Expect = 0.041
Identities = 26/140 (18%), Positives = 60/140 (42%), Gaps = 4/140 (2%)
Frame = +1
Query: 85 RTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQK 264
R + L ++ ++L WL E +L + + N ++I+++LN+ +E Q+
Sbjct: 31 RVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNS-EEIQRKLNEQQELQR 89
Query: 265 ALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMITDMKTKWTTVCSKAVDRQRKL 432
+ + + L A + + ++ ++ +W +C+ +++R+ K+
Sbjct: 90 DIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKI 149
Query: 433 EEALLYSGQFKDAMSALLDW 492
EE +F D S DW
Sbjct: 150 EETWRLWQKFLDDYSRFEDW 169
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 233 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 292
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 293 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 348
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 349 RYCQEVFGRVERYHKKL 365
>AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein.
Length = 8749
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 8372 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 8431
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 8432 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 8490
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 8491 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 8549
Query: 592 DLH 600
H
Sbjct: 8550 IKH 8552
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 7466 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 7523
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 7524 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 7583
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 7584 KSASMRLEEQKKKL 7597
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 7675 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 7734
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 7735 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 7788
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 7789 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 7829
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 7784 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 7843
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 7844 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 7902
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 7903 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 7943
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 7904 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 7963
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 7964 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 8021
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 8022 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 8079
Query: 580 QFEEDL 597
F++++
Sbjct: 8080 AFQQEI 8085
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 6705 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 6764
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 6765 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 6823
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 6824 IPAVQEKLHQLQMDKLPSRHAISEVMSW 6851
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/168 (19%), Positives = 78/168 (46%), Gaps = 5/168 (2%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K+ +I+ L +++ W ++S S L+ + ++ + N L W+ ++++
Sbjct: 2704 KEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKI 2763
Query: 184 DQ-LNSEATVNDP----DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE 348
+ L + + + D ++ L++ + +AL + L K+ + L +K DE
Sbjct: 2764 EHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRAL------HRLIAKS-RELYEKTE--DE 2814
Query: 349 NPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ T ++KT++ + + A ++ RK+EE + + DA+ DW
Sbjct: 2815 SFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDW 2862
Score = 39.5 bits (88), Expect = 0.010
Identities = 28/103 (27%), Positives = 51/103 (49%)
Frame = +1
Query: 97 LDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALAS 276
L+ G AKEFSD L W+ E +E L + E + +K K +L+K++ Q+ + S
Sbjct: 3796 LEKGLHLAKEFSDKCKALTQWIAEYQEIL-HVPEEPKMELYEK-KAQLSKYKSLQQTVLS 3853
Query: 277 KQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCS 405
+P+ + G+ L + + LK I +++ + +CS
Sbjct: 3854 HEPSVKSVREKGEALLELV---QDVTLKDKIDQLQSDYQDLCS 3893
Score = 37.1 bits (82), Expect = 0.054
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 4/106 (3%)
Frame = +1
Query: 139 WNNLMNWLNETEEQLDQ-LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK 315
+ NL + +++ E + + T+ D + +K +KH + + KQ D GK
Sbjct: 2098 YQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGK 2157
Query: 316 HLKDKAPKGDENPLKTMITDMKT---KWTTVCSKAVDRQRKLEEAL 444
HL + K + + TDM++ KW V K + +L +L
Sbjct: 2158 HLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSL 2203
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 8007 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 8066
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 8067 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 8122
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 8123 RYCQEVFGRVERYHKKL 8139
Score = 36.3 bits (80), Expect = 0.095
Identities = 34/165 (20%), Positives = 69/165 (41%), Gaps = 2/165 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
KQ V I+ + ++ + + + +AL E F D L W++E EE+
Sbjct: 2486 KQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERF 2545
Query: 184 DQLN-SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA-PKGDENPL 357
+ N E+ + P+K K ++K F L + + + D + G+ L ++ G E L
Sbjct: 2546 NTENLGESKQHIPEK-KNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRL 2604
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + T + ++ R + AL ++A+ ++ W
Sbjct: 2605 ---CSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFW 2646
Score = 33.9 bits (74), Expect = 0.51
Identities = 31/173 (17%), Positives = 64/173 (36%), Gaps = 1/173 (0%)
Frame = +1
Query: 82 ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQ 261
E+ LD E +FS L +W+ + LD +D + R K
Sbjct: 3277 EKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCH--PTSDKSVLDSRTLKLEALL 3334
Query: 262 KALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEE 438
K+ + + G+ L++ +P+G ++ + +K W ++ S + + +LE
Sbjct: 3335 SVKQEKEIQMKMIVTRGESVLQNTSPEGIPT-IQQQLQSVKDMWASLLSAGIRCKSQLEG 3393
Query: 439 ALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
AL ++D + W H +L ++ + K E++
Sbjct: 3394 ALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEV 3446
Score = 32.3 bits (70), Expect = 1.5
Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
+ +V RW R+ + + ++ + L+ E W N + + E +DQL + +
Sbjct: 5114 MTTVWQRWTRLRAVAQDQEKILEDAVDE-------WTGFNNKVKKATEMIDQLQDKLPGS 5166
Query: 214 DPDKIKQR-----LNKHREFQKALASKQPAYD-LTMKTGKHLKDKA--PKGDENPLKTMI 369
+K + L H F L +Q A L +T L+D A G+E PL I
Sbjct: 5167 SAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEI 5226
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEAL 444
T M+ + + K + +++ L
Sbjct: 5227 TAMQDRCLNMQEKVKTNGKLVKQEL 5251
Score = 29.9 bits (64), Expect = 8.2
Identities = 23/157 (14%), Positives = 70/157 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + + W+ S ++ AL++ + K+F + +WL++TE+ + + +S
Sbjct: 3150 IQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHE-SSN 3208
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ P K +++ K + + + +P + + + L + + + ++ +
Sbjct: 3209 RLYDLPAKRREQ-QKLQSVLEEIHCYEPQLNRLKEKAQQLWE--GQAASKSFRHRVSQLS 3265
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + ++ +L+ + QF + L DW
Sbjct: 3266 SQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDW 3302
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/151 (16%), Positives = 54/151 (35%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D L+K ++ RW ++ + + +E + LM W E + + +
Sbjct: 4239 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 4298
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ PD + L H L +KQ +K + + ++ +
Sbjct: 4299 ALKQSP--PPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKAL 4356
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF 462
+D ++ + R++ L +AL QF
Sbjct: 4357 SDAQSHVNCLSDLVGQRRKYLNKALSEKTQF 4387
>AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein.
Length = 8797
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 8420 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 8479
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 8480 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 8538
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 8539 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 8597
Query: 592 DLH 600
H
Sbjct: 8598 IKH 8600
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 7537 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 7594
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 7595 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 7654
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 7655 KSASMRLEEQKKKL 7668
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 7746 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 7805
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 7806 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 7859
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 7860 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 7900
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 7855 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 7914
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 7915 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 7973
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 7974 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 8014
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 7975 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 8034
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 8035 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 8092
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 8093 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 8150
Query: 580 QFEEDL 597
F++++
Sbjct: 8151 AFQQEI 8156
Score = 43.6 bits (98), Expect = 6e-04
Identities = 37/168 (22%), Positives = 70/168 (41%), Gaps = 1/168 (0%)
Frame = +1
Query: 97 LDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALAS 276
L+ G AKEFSD L W+ E +E L + E + +K K +L+K++ Q+ + S
Sbjct: 3811 LEKGLHLAKEFSDKCKALTQWIAEYQEIL-HVPEEPKMELYEK-KAQLSKYKSLQQTVLS 3868
Query: 277 KQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSG 456
+P+ + G+ L + + LK I +++ + +CS + LE +
Sbjct: 3869 HEPSVKSVREKGEALLELV---QDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHE 3925
Query: 457 QFKDAMSALLDWXXXXXXXXEG-DAPVHGDLDTVMALIEQHKQFEEDL 597
+ + + W D L+T+ + HK E++
Sbjct: 3926 DYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEI 3973
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/148 (18%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATV--NDPDKI 228
W +K ++ L+ K + +L++WL +++L+ ++ + + +
Sbjct: 6776 WLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMV 6835
Query: 229 KQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSK 408
+ LN EF K + ++ + TG L + K D L++ ++ + ++WT + +
Sbjct: 6836 RDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLL-RLKKVDTATLRSELSRIDSQWTDLLTN 6894
Query: 409 AVDRQRKLEEALLYSGQFKDAMSALLDW 492
Q KL + + + A+S ++ W
Sbjct: 6895 IPAVQEKLHQLQMDKLPSRHAISEVMSW 6922
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/168 (19%), Positives = 78/168 (46%), Gaps = 5/168 (2%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K+ +I+ L +++ W ++S S L+ + ++ + N L W+ ++++
Sbjct: 2697 KEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKI 2756
Query: 184 DQ-LNSEATVNDP----DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDE 348
+ L + + + D ++ L++ + +AL + L K+ + L +K DE
Sbjct: 2757 EHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRAL------HRLIAKS-RELYEKTE--DE 2807
Query: 349 NPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ T ++KT++ + + A ++ RK+EE + + DA+ DW
Sbjct: 2808 SFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDW 2855
Score = 37.1 bits (82), Expect = 0.054
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 4/106 (3%)
Frame = +1
Query: 139 WNNLMNWLNETEEQLDQ-LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK 315
+ NL + +++ E + + T+ D + +K +KH + + KQ D GK
Sbjct: 2091 YQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGK 2150
Query: 316 HLKDKAPKGDENPLKTMITDMKT---KWTTVCSKAVDRQRKLEEAL 444
HL + K + + TDM++ KW V K + +L +L
Sbjct: 2151 HLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSL 2196
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 8078 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 8137
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 8138 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 8193
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 8194 RYCQEVFGRVERYHKKL 8210
Score = 36.3 bits (80), Expect = 0.095
Identities = 34/165 (20%), Positives = 69/165 (41%), Gaps = 2/165 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
KQ V I+ + ++ + + + +AL E F D L W++E EE+
Sbjct: 2479 KQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERF 2538
Query: 184 DQLN-SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA-PKGDENPL 357
+ N E+ + P+K K ++K F L + + + D + G+ L ++ G E L
Sbjct: 2539 NTENLGESKQHIPEK-KNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRL 2597
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + T + ++ R + AL ++A+ ++ W
Sbjct: 2598 ---CSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFW 2639
Score = 33.9 bits (74), Expect = 0.51
Identities = 31/173 (17%), Positives = 64/173 (36%), Gaps = 1/173 (0%)
Frame = +1
Query: 82 ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQ 261
E+ LD E +FS L +W+ + LD +D + R K
Sbjct: 3270 EKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCH--PTSDKSVLDSRTLKLEALL 3327
Query: 262 KALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEE 438
K+ + + G+ L++ +P+G ++ + +K W ++ S + + +LE
Sbjct: 3328 SVKQEKEIQMKMIVTRGESVLQNTSPEGIPT-IQQQLQSVKDMWASLLSAGIRCKSQLEG 3386
Query: 439 ALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
AL ++D + W H +L ++ + K E++
Sbjct: 3387 ALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEV 3439
Score = 32.3 bits (70), Expect = 1.5
Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
+ +V RW R+ + + ++ + L+ E W N + + E +DQL + +
Sbjct: 5185 MTTVWQRWTRLRAVAQDQEKILEDAVDE-------WTGFNNKVKKATEMIDQLQDKLPGS 5237
Query: 214 DPDKIKQR-----LNKHREFQKALASKQPAYD-LTMKTGKHLKDKA--PKGDENPLKTMI 369
+K + L H F L +Q A L +T L+D A G+E PL I
Sbjct: 5238 SAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEI 5297
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEAL 444
T M+ + + K + +++ L
Sbjct: 5298 TAMQDRCLNMQEKVKTNGKLVKQEL 5322
Score = 29.9 bits (64), Expect = 8.2
Identities = 23/157 (14%), Positives = 70/157 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + + W+ S ++ AL++ + K+F + +WL++TE+ + + +S
Sbjct: 3143 IQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHE-SSN 3201
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ P K +++ K + + + +P + + + L + + + ++ +
Sbjct: 3202 RLYDLPAKRREQ-QKLQSVLEEIHCYEPQLNRLKEKAQQLWE--GQAASKSFRHRVSQLS 3258
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + ++ +L+ + QF + L DW
Sbjct: 3259 SQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDW 3295
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/151 (16%), Positives = 54/151 (35%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D L+K ++ RW ++ + + +E + LM W E + + +
Sbjct: 4310 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 4369
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ PD + L H L +KQ +K + + ++ +
Sbjct: 4370 ALKQSP--PPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKAL 4427
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF 462
+D ++ + R++ L +AL QF
Sbjct: 4428 SDAQSHVNCLSDLVGQRRKYLNKALSEKTQF 4458
>AF444779-1|AAL38031.1| 1139|Homo sapiens myocyte inner nuclear
membrane protein protein.
Length = 1139
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 762 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 821
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 822 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 880
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 881 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 939
Query: 592 DLH 600
H
Sbjct: 940 IKH 942
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 88 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 147
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 148 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 201
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 202 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 242
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 197 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 256
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 257 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 315
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 316 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 356
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 317 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 376
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 377 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 434
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 435 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 492
Query: 580 QFEEDL 597
F++++
Sbjct: 493 AFQQEI 498
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 420 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 479
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 480 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 535
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 536 RYCQEVFGRVERYHKKL 552
>AB018339-1|BAA34516.2| 1876|Homo sapiens KIAA0796 protein protein.
Length = 1876
Score = 65.7 bits (153), Expect = 1e-10
Identities = 43/183 (23%), Positives = 85/183 (46%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + +++ + + ++ ++F+ N++ WL +TEE+L+QL D I+
Sbjct: 1499 RWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIE 1558
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
++ K +E QKA+ ++ A L++ +A + L+ ++ M +W VCS
Sbjct: 1559 LQIKKLKELQKAVDHRK-AIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLL 1617
Query: 412 VDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEE 591
+ + L++AL+ F + LL P+ +LD + L + HKQ +
Sbjct: 1618 EEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQ 1676
Query: 592 DLH 600
H
Sbjct: 1677 IKH 1679
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + ++W+ V+ ++ +R +D ++ + + +M L WL E ++ +V
Sbjct: 616 LTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWL--VEVSYLPMSGLGSVP 673
Query: 214 DPDKIKQRLNKHREF-QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
P + + L +F +K +Q +Y LT++ GK L A G E L+ + +++ KW
Sbjct: 674 IPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKW 733
Query: 391 TTVCSKAVDRQRKL 432
+ + ++++KL
Sbjct: 734 KSASMRLEEQKKKL 747
Score = 47.6 bits (108), Expect = 4e-05
Identities = 32/161 (19%), Positives = 73/161 (45%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D+ ++ + +Q +WE + + + R + + E FS+ L WL + E ++ Q
Sbjct: 825 DISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQ 884
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
N + + +++ ++L K ++Q+ +A Q + G+ L + + + ++ +
Sbjct: 885 -NGDILI---EEMIEKLKK--DYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKL 938
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W + R +KL+E L+ Q MS+L W
Sbjct: 939 GKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW 979
Score = 47.2 bits (107), Expect = 5e-05
Identities = 32/161 (19%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ L V RW+ ++ A R + L ++ ++L WL E +L +
Sbjct: 934 IEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVY 993
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK----APKGDENPLKTMI 369
+ N ++I+++LN+ +E Q+ + + + L A + + ++
Sbjct: 994 DSCNS-EEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT 1052
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
++ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 1053 RNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDW 1093
Score = 46.4 bits (105), Expect = 9e-05
Identities = 36/186 (19%), Positives = 75/186 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
++ RW + + S ER ++ ++ ++F D ++ +WL +E +S +
Sbjct: 1054 NLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTV 1113
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L K FQ+ + +L K + L + LK M+ + +W +
Sbjct: 1114 --AKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNL 1171
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHK 579
+ R+L+ + +F+ A ++L W H V A I+Q K
Sbjct: 1172 QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIE--HFSECDVQAKIKQLK 1229
Query: 580 QFEEDL 597
F++++
Sbjct: 1230 AFQQEI 1235
Score = 37.1 bits (82), Expect = 0.054
Identities = 26/137 (18%), Positives = 59/137 (43%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF ++++ WL E + QL +
Sbjct: 1157 LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHF 1216
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ + KIKQ + FQ+ ++ + + G+ L +K+ D ++ + +++
Sbjct: 1217 SECDVQAKIKQL----KAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELR 1272
Query: 382 TKWTTVCSKAVDRQRKL 432
V + +KL
Sbjct: 1273 RYCQEVFGRVERYHKKL 1289
>AF043290-1|AAC02992.1| 374|Homo sapiens lymphocyte membrane
associated protein protein.
Length = 374
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/160 (25%), Positives = 74/160 (46%)
Frame = +1
Query: 121 KEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLT 300
++F+ N++ WL +TEE+L+QL D I+ ++ K +E QKA+ ++ A L+
Sbjct: 9 QQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRK-AIILS 67
Query: 301 MKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSA 480
+ +A + L+ ++ M +W VCS + + L++AL+ F +
Sbjct: 68 INLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHG 127
Query: 481 LLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDLH 600
LL P+ +LD + L + HKQ + H
Sbjct: 128 LLLMLENIDRRKNEIVPIDSNLDAEI-LQDHHKQLMQIKH 166
>U83867-1|AAB41498.1| 2477|Homo sapiens alpha II spectrin protein.
Length = 2477
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 1/196 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1736 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1792
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1793 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1850
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1851 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1907
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 1908 AAIQGLLKKHEAFETD 1923
Score = 43.2 bits (97), Expect = 8e-04
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ + WL+E E L SE
Sbjct: 1634 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDFDFWLSEVEA---LLASE 1689
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1690 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1747
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1748 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1805
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1806 NLRKKHKRLEAEL 1818
Score = 40.3 bits (90), Expect = 0.006
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 22 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 76
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 77 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 135
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 136 EKMREKGIKLLQAQKLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 193
Query: 583 FEEDL 597
F+ D+
Sbjct: 194 FQTDM 198
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 542 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 594
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 595 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 652
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 653 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 710
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 711 TNVQNLQKKHALLE--------ADVAAHQDR 733
Score = 35.9 bits (79), Expect = 0.13
Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 5/163 (3%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1459 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1515
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1516 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1571
Query: 508 XXXEGDA---PVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ P + L +++ ++H+ FE +LH AD +R
Sbjct: 1572 QTASDESYKDPTNIQLSKLLSKHQKHQAFEAELH--ANADRIR 1612
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 916
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 917 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 966
Score = 31.1 bits (67), Expect = 3.6
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 481 NWMSKQEAFL--LNEDLG-DSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 537
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 538 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 595
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 596 ATDEA--YKDPSNLQGKVQKHQAFEAEL 621
>BC053521-1|AAH53521.1| 2452|Homo sapiens SPTAN1 protein protein.
Length = 2452
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 1/196 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1711 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1767
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1768 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1825
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1826 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1882
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 1883 AAIQGLLKKHEAFETD 1898
Score = 43.2 bits (97), Expect = 8e-04
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ + WL+E E L SE
Sbjct: 1609 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDFDFWLSEVEA---LLASE 1664
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1665 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1722
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1723 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1780
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1781 NLRKKHKRLEAEL 1793
Score = 40.3 bits (90), Expect = 0.006
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 22 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 76
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 77 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 135
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 136 EKMREKGIKLLQAQKLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 193
Query: 583 FEEDL 597
F+ D+
Sbjct: 194 FQTDM 198
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 542 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 594
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 595 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 652
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 653 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 710
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 711 TNVQNLQKKHALLE--------ADVAAHQDR 733
Score = 34.7 bits (76), Expect = 0.29
Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1439 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1495
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1496 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1551
Query: 508 XXXEGDAPVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ + D + + ++H+ FE +LH AD +R
Sbjct: 1552 QTASDES--YKDPTNIQSKHQKHQAFEAELH--ANADRIR 1587
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 916
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 917 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 966
Score = 31.1 bits (67), Expect = 3.6
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 481 NWMSKQEAFL--LNEDLG-DSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 537
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 538 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 595
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 596 ATDEA--YKDPSNLQGKVQKHQAFEAEL 621
>AL356481-4|CAH71405.1| 2472|Homo sapiens spectrin, alpha,
non-erythrocytic 1 (alpha-fodrin) protein.
Length = 2472
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 1/196 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1731 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1787
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1788 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1845
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1846 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1902
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 1903 AAIQGLLKKHEAFETD 1918
Score = 43.2 bits (97), Expect = 8e-04
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ + WL+E E L SE
Sbjct: 1629 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDFDFWLSEVEA---LLASE 1684
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1685 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1742
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1743 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1800
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1801 NLRKKHKRLEAEL 1813
Score = 40.3 bits (90), Expect = 0.006
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 22 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 76
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 77 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 135
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 136 EKMREKGIKLLQAQKLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 193
Query: 583 FEEDL 597
F+ D+
Sbjct: 194 FQTDM 198
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 542 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 594
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 595 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 652
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 653 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 710
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 711 TNVQNLQKKHALLE--------ADVAAHQDR 733
Score = 34.7 bits (76), Expect = 0.29
Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1459 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1515
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1516 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1571
Query: 508 XXXEGDAPVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ + D + + ++H+ FE +LH AD +R
Sbjct: 1572 QTASDES--YKDPTNIQSKHQKHQAFEAELH--ANADRIR 1607
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 916
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 917 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 966
Score = 31.1 bits (67), Expect = 3.6
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 481 NWMSKQEAFL--LNEDLG-DSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 537
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 538 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 595
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 596 ATDEA--YKDPSNLQGKVQKHQAFEAEL 621
>AL356481-3|CAH71404.1| 2477|Homo sapiens spectrin, alpha,
non-erythrocytic 1 (alpha-fodrin) protein.
Length = 2477
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 1/196 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1736 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1792
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1793 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1850
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1851 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1907
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 1908 AAIQGLLKKHEAFETD 1923
Score = 43.2 bits (97), Expect = 8e-04
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ + WL+E E L SE
Sbjct: 1634 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDFDFWLSEVEA---LLASE 1689
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1690 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1747
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1748 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1805
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1806 NLRKKHKRLEAEL 1818
Score = 40.3 bits (90), Expect = 0.006
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 22 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 76
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 77 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 135
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 136 EKMREKGIKLLQAQKLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 193
Query: 583 FEEDL 597
F+ D+
Sbjct: 194 FQTDM 198
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 542 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 594
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 595 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 652
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 653 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 710
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 711 TNVQNLQKKHALLE--------ADVAAHQDR 733
Score = 35.9 bits (79), Expect = 0.13
Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 5/163 (3%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1459 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1515
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1516 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1571
Query: 508 XXXEGDA---PVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ P + L +++ ++H+ FE +LH AD +R
Sbjct: 1572 QTASDESYKDPTNIQLSKLLSKHQKHQAFEAELH--ANADRIR 1612
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 916
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 917 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 966
Score = 31.1 bits (67), Expect = 3.6
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 481 NWMSKQEAFL--LNEDLG-DSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 537
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 538 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 595
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 596 ATDEA--YKDPSNLQGKVQKHQAFEAEL 621
>AB209860-1|BAD93097.1| 2506|Homo sapiens spectrin, alpha,
non-erythrocytic 1 (alpha-fodrin) variant protein.
Length = 2506
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 1/196 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1765 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1821
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1822 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1879
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1880 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1936
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 1937 AAIQGLLKKHEAFETD 1952
Score = 43.2 bits (97), Expect = 8e-04
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ + WL+E E L SE
Sbjct: 1663 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDFDFWLSEVEA---LLASE 1718
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1719 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1776
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1777 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1834
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1835 NLRKKHKRLEAEL 1847
Score = 40.3 bits (90), Expect = 0.006
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 56 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 110
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 111 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 169
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 170 EKMREKGIKLLQAQKLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 227
Query: 583 FEEDL 597
F+ D+
Sbjct: 228 FQTDM 232
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 576 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 628
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 629 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 686
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 687 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 744
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 745 TNVQNLQKKHALLE--------ADVAAHQDR 767
Score = 34.7 bits (76), Expect = 0.29
Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1493 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1549
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1550 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1605
Query: 508 XXXEGDAPVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ + D + + ++H+ FE +LH AD +R
Sbjct: 1606 QTASDES--YKDPTNIQSKHQKHQAFEAELH--ANADRIR 1641
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 895 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 950
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 951 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 1000
Score = 31.1 bits (67), Expect = 3.6
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 515 NWMSKQEAFL--LNEDLG-DSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 571
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 572 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 629
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 630 ATDEA--YKDPSNLQGKVQKHQAFEAEL 655
>AB191262-1|BAD52438.1| 2452|Homo sapiens non-erythrocytic spectrin
alpha protein.
Length = 2452
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 1/196 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1711 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1767
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1768 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1825
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1826 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1882
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 1883 AAIQGLLKKHEAFETD 1898
Score = 43.2 bits (97), Expect = 8e-04
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ + WL+E E L SE
Sbjct: 1609 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDFDFWLSEVEA---LLASE 1664
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1665 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1722
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1723 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1780
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1781 NLRKKHKRLEAEL 1793
Score = 40.3 bits (90), Expect = 0.006
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 22 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 76
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 77 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 135
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 136 EKMREKGIKLLQAQKLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 193
Query: 583 FEEDL 597
F+ D+
Sbjct: 194 FQTDM 198
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 542 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 594
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 595 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 652
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 653 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 710
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 711 TNVQNLQKKHALLE--------ADVAAHQDR 733
Score = 34.7 bits (76), Expect = 0.29
Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1439 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1495
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1496 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1551
Query: 508 XXXEGDAPVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ + D + + ++H+ FE +LH AD +R
Sbjct: 1552 QTASDES--YKDPTNIQSKHQKHQAFEAELH--ANADRIR 1587
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 916
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 917 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 966
Score = 31.1 bits (67), Expect = 3.6
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 481 NWMSKQEAFL--LNEDLG-DSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 537
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 538 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 595
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 596 ATDEA--YKDPSNLQGKVQKHQAFEAEL 621
>J05243-1|AAA51790.1| 2472|Homo sapiens SPTAN1 protein.
Length = 2472
Score = 54.0 bits (124), Expect = 4e-07
Identities = 46/194 (23%), Positives = 86/194 (44%), Gaps = 1/194 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +K+ ++ R++++ S +A R L+ + + F DM ++ +W+ E + +
Sbjct: 1731 DTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDM-DDEESWIKEKKLLV-- 1787
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 1788 -GSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE-IQQRL 1845
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 1846 AQFVEHWKELKQLAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 1902
Query: 547 DTVMALIEQHKQFE 588
+ L+++H+ FE
Sbjct: 1903 AAIQGLLKKHEAFE 1916
Score = 44.8 bits (101), Expect = 3e-04
Identities = 46/193 (23%), Positives = 83/193 (43%), Gaps = 1/193 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L ++ +W+ +V KSAE+++ L K+ + F+ ++ WL+E E L SE
Sbjct: 1629 VKARLAALADQWQFLVQKSAEKSQKLKEANKQ-QNFNTGIKDIAFWLSEVEA---LLASE 1684
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + L KH+ + +++ + DL + + A D + +K +
Sbjct: 1685 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA--FDTSQVKDKRDTI 1742
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVM 558
++ + S A R+ KL E+ F+D M W G DL V
Sbjct: 1743 NGRFQKIKSMAASRRAKLNESHRLHQFFRD-MDDEESWIKEKKLLV-GSEDYGRDLTGVQ 1800
Query: 559 ALIEQHKQFEEDL 597
L ++HK+ E +L
Sbjct: 1801 NLRKKHKRLEAEL 1813
Score = 39.9 bits (89), Expect = 0.008
Identities = 38/185 (20%), Positives = 81/185 (43%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V R+ R S R + L+ ++ + F L W+ +E+L Q+ S+ DP
Sbjct: 22 VLDRYHRFKELSTLRRQKLEDSYR-FQFFQRDAEELEKWI---QEKL-QIASDENYKDPT 76
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
++ +L KH+ F+ + + A +TG + + E ++T + ++ +W +
Sbjct: 77 NLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASET-IRTRLMELHRQWELLL 135
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
K ++ KL +A Q+ ++DW + + DL+ V L ++ ++
Sbjct: 136 EKMREKGIKLLQAQNLV-QYLRECEDVMDWINDKEAIVTSE-ELGQDLEHVEVLQKKFEE 193
Query: 583 FEEDL 597
F+ D+
Sbjct: 194 FQTDM 198
Score = 37.9 bits (84), Expect = 0.031
Identities = 49/211 (23%), Positives = 84/211 (39%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV ++ L+S R + ++ R L F + F D + L +W+NE ++
Sbjct: 542 EDVATRRDALLS---RRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNE---KMK 594
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
EA DP ++ ++ KH+ F+ L++ Q D K G+ L D ++ +
Sbjct: 595 TATDEA-YKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLID-VNHYAKDEVAAR 652
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDL 546
+ ++ + W + + KL EA QF + + W D DL
Sbjct: 653 MNEVISLWKKLLEATELKGIKLREA-NQQQQFNRNVEDIELWLYEVEGHLASD-DYGKDL 710
Query: 547 DTVMALIEQHKQFEEDLHFARAADAVRHQDR 639
V L ++H E AD HQDR
Sbjct: 711 TNVQNLQKKHALLE--------ADVAAHQDR 733
Score = 34.7 bits (76), Expect = 0.29
Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL--KD 327
NW+ E L N+E + D ++ + KH +F KA+ ++ L
Sbjct: 1459 NWMAAREAFL---NTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAG 1515
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
KGD + + + D +W + ++ ++++ KL E+ QF + + W
Sbjct: 1516 HYAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGESQTLQ-QFSRDVDEIEAWISEKL 1571
Query: 508 XXXEGDAPVHGDLDTVMALIEQHKQFEEDLHFARAADAVR 627
++ + D + + ++H+ FE +LH AD +R
Sbjct: 1572 QTASDES--YKDPTNIQSKHQKHQAFEAELH--ANADRIR 1607
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 916
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 917 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 966
Score = 29.9 bits (64), Expect = 8.2
Identities = 29/148 (19%), Positives = 66/148 (44%)
Frame = +1
Query: 154 NWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
NW+++ E L LN + + D ++ L KH +F+K+L++++ + L
Sbjct: 481 NWMSKQEAFL--LNEDLG-DFLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN 537
Query: 334 PKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXX 513
E+ + T + ++ + +A+ R+ +L ++ F+D+ L W
Sbjct: 538 HYAMED-VATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDS-DELKSWVNEKMKT 595
Query: 514 XEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+A + D + +++H+ FE +L
Sbjct: 596 ATDEA--YKDPSNLQGKVQKHQAFEAEL 621
>AY061759-1|AAL33802.1| 3270|Homo sapiens nesprin-2 gamma protein.
Length = 3270
Score = 53.2 bits (122), Expect = 8e-07
Identities = 36/198 (18%), Positives = 77/198 (38%), Gaps = 4/198 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + ++ +W + K L K ++ + L WL ++ L+ +
Sbjct: 1299 LEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWKEQ 1358
Query: 202 A--TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
+ D D I+ +N EF K + K + G L + D L+ +
Sbjct: 1359 SLNVSQDLDTIRSNINNFFEFSKEVDEKSSLKTAVISIGNQLLH-LKETDTATLRASLAQ 1417
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVH--GDLD 549
+ KWT + ++ D Q KL + + + A++ ++ W + VH
Sbjct: 1418 FEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSAS 1477
Query: 550 TVMALIEQHKQFEEDLHF 603
V L+++HK+F ++ +
Sbjct: 1478 QVKHLLQKHKEFRMEMDY 1495
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 2377 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 2435
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 2436 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 2495
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2496 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 2536
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 2497 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 2554
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 2555 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 2614
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 2615 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 2645
Score = 38.3 bits (85), Expect = 0.023
Identities = 27/167 (16%), Positives = 68/167 (40%), Gaps = 3/167 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D ++ L + +W ++++ + L E +++W+N E Q
Sbjct: 1404 KETDTATLRASLAQFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQ 1463
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD---KAPKGDEN 351
+S + + ++K L KH+EF+ + KQ D ++ L ++ + +
Sbjct: 1464 TSDEDSVHSPSSASQVKHLLQKHKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERT 1523
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +M +W V + + L++ L + ++ + L +W
Sbjct: 1524 EFAEHLGEMNRQWHRVHGMLNRKIQHLDQLLESITESENKIQILNNW 1570
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 2600 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 2659
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 2660 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 2699
Score = 32.7 bits (71), Expect = 1.2
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 13/135 (9%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W RV + + LD + E + L NWL EE+L L +V
Sbjct: 1529 LGEMNRQWHRVHGMLNRKIQHLDQLLESITESENKIQILNNWLEAQEERLKTLQKPESVI 1588
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYD------LTMKTG--KHLKDKAPKGDE-----NP 354
K+ L ++ + LA K A D LT+++G L+D A + DE +
Sbjct: 1589 SVQKL---LLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASRIDELFQKRSS 1645
Query: 355 LKTMITDMKTKWTTV 399
+ T + +KT +V
Sbjct: 1646 VLTQVNQLKTSMQSV 1660
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 2267 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 2326
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 2327 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 2380
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 2381 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 2422
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 3027 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 3086
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 3087 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 3139
>AF495911-1|AAN60443.1| 6884|Homo sapiens nesprin-2 protein.
Length = 6884
Score = 53.2 bits (122), Expect = 8e-07
Identities = 36/198 (18%), Positives = 77/198 (38%), Gaps = 4/198 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + ++ +W + K L K ++ + L WL ++ L+ +
Sbjct: 4913 LEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWKEQ 4972
Query: 202 A--TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
+ D D I+ +N EF K + K + G L + D L+ +
Sbjct: 4973 SLNVSQDLDTIRSNINNFFEFSKEVDEKSSLKTAVISIGNQLLH-LKETDTATLRASLAQ 5031
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVH--GDLD 549
+ KWT + ++ D Q KL + + + A++ ++ W + VH
Sbjct: 5032 FEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSAS 5091
Query: 550 TVMALIEQHKQFEEDLHF 603
V L+++HK+F ++ +
Sbjct: 5092 QVKHLLQKHKEFRMEMDY 5109
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 5991 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 6049
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 6050 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 6109
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 6110 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 6150
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 6111 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 6168
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 6169 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 6228
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 6229 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 6259
Score = 38.3 bits (85), Expect = 0.023
Identities = 27/167 (16%), Positives = 68/167 (40%), Gaps = 3/167 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D ++ L + +W ++++ + L E +++W+N E Q
Sbjct: 5018 KETDTATLRASLAQFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQ 5077
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD---KAPKGDEN 351
+S + + ++K L KH+EF+ + KQ D ++ L ++ + +
Sbjct: 5078 TSDEDSVHSPSSASQVKHLLQKHKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERT 5137
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +M +W V + + L++ L + ++ + L +W
Sbjct: 5138 EFAEHLGEMNRQWHRVHGMLNRKIQHLDQLLESITESENKIQILNNW 5184
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 6214 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 6273
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 6274 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 6313
Score = 32.7 bits (71), Expect = 1.2
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 13/135 (9%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W RV + + LD + E + L NWL EE+L L +V
Sbjct: 5143 LGEMNRQWHRVHGMLNRKIQHLDQLLESITESENKIQILNNWLEAQEERLKTLQKPESVI 5202
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYD------LTMKTG--KHLKDKAPKGDE-----NP 354
K+ L ++ + LA K A D LT+++G L+D A + DE +
Sbjct: 5203 SVQKL---LLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASRIDELFQKRSS 5259
Query: 355 LKTMITDMKTKWTTV 399
+ T + +KT +V
Sbjct: 5260 VLTQVNQLKTSMQSV 5274
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 5881 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 5940
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 5941 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 5994
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 5995 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 6036
Score = 31.9 bits (69), Expect = 2.0
Identities = 31/153 (20%), Positives = 70/153 (45%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
+++++I+ L+ R +S+ E + L E + F+D+ +++++W+ E +E
Sbjct: 2006 EEEEIIMEATCLMDRYQTLLRQLSEIEEEDKLLP---TEDQSFNDLAHDVIHWIKEIKES 2062
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L LNS +++R+ K +E + +P D ++T + +A + ++
Sbjct: 2063 LMVLNSS---EGKMPLEERIQKIKE----IILLKPEGDARIET---IMKQAESSEAPLVQ 2112
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQ 459
+TD+ +W A +E LL G+
Sbjct: 2113 KTLTDISNQWDNTLHLA-STYLSHQEKLLLEGE 2144
Score = 30.3 bits (65), Expect = 6.2
Identities = 26/130 (20%), Positives = 57/130 (43%)
Frame = +1
Query: 28 NLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEAT 207
NL++ Q ++++V ++ RT L+ + +E+SD+ + W+ T L A
Sbjct: 3757 NLMIPFQ-QYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLL------AN 3809
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTK 387
D D ++ + Q AL + ++L L+D + + + L I ++ +
Sbjct: 3810 PADYDSLRTLSHHASTVQMALEDSEQKHNLLHSIFMDLEDLSIIFETDELTQSIQELSNQ 3869
Query: 388 WTTVCSKAVD 417
T + K ++
Sbjct: 3870 VTALQQKIME 3879
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 6641 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 6700
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 6701 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 6753
>AF435011-1|AAL33548.1| 6885|Homo sapiens NUANCE protein.
Length = 6885
Score = 53.2 bits (122), Expect = 8e-07
Identities = 36/198 (18%), Positives = 77/198 (38%), Gaps = 4/198 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + ++ +W + K L K ++ + L WL ++ L+ +
Sbjct: 4914 LEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWKEQ 4973
Query: 202 A--TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
+ D D I+ +N EF K + K + G L + D L+ +
Sbjct: 4974 SLNVSQDLDTIRSNINNFFEFSKEVDEKSSLKTAVISIGNQLLH-LKETDTATLRASLAQ 5032
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVH--GDLD 549
+ KWT + ++ D Q KL + + + A++ ++ W + VH
Sbjct: 5033 FEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSAS 5092
Query: 550 TVMALIEQHKQFEEDLHF 603
V L+++HK+F ++ +
Sbjct: 5093 QVKHLLQKHKEFRMEMDY 5110
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 5992 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 6050
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 6051 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 6110
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 6111 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 6151
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 6112 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 6169
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 6170 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 6229
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 6230 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 6260
Score = 39.5 bits (88), Expect = 0.010
Identities = 28/167 (16%), Positives = 68/167 (40%), Gaps = 3/167 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D ++ L + +W ++++ + L E +++W+N E Q
Sbjct: 5019 KETDTATLRASLAQFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQ 5078
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD---KAPKGDEN 351
+S + + ++K L KH+EF+ + KQ D ++ L ++ + +
Sbjct: 5079 TSDEDSVHSPSSASQVKHLLQKHKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERT 5138
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +M +W V + + LE+ L + ++ + L +W
Sbjct: 5139 EFAEHLGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNW 5185
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 6215 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 6274
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 6275 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 6314
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 5882 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 5941
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 5942 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 5995
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 5996 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 6037
Score = 31.9 bits (69), Expect = 2.0
Identities = 31/153 (20%), Positives = 70/153 (45%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
+++++I+ L+ R +S+ E + L E + F+D+ +++++W+ E +E
Sbjct: 2007 EEEEIIMEATCLMDRYQTLLRQLSEIEEEDKLLP---TEDQSFNDLAHDVIHWIKEIKES 2063
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
L LNS +++R+ K +E + +P D ++T + +A + ++
Sbjct: 2064 LMVLNSS---EGKMPLEERIQKIKE----IILLKPEGDARIET---IMKQAESSEAPLVQ 2113
Query: 361 TMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQ 459
+TD+ +W A +E LL G+
Sbjct: 2114 KTLTDISNQWDNTLHLA-STYLSHQEKLLLEGE 2145
Score = 30.3 bits (65), Expect = 6.2
Identities = 26/130 (20%), Positives = 57/130 (43%)
Frame = +1
Query: 28 NLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEAT 207
NL++ Q ++++V ++ RT L+ + +E+SD+ + W+ T L A
Sbjct: 3758 NLMIPFQ-QYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLL------AN 3810
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTK 387
D D ++ + Q AL + ++L L+D + + + L I ++ +
Sbjct: 3811 PADYDSLRTLSHHASTVQMALEDSEQKHNLLHSIFMDLEDLSIIFETDELTQSIQELSNQ 3870
Query: 388 WTTVCSKAVD 417
T + K ++
Sbjct: 3871 VTALQQKIME 3880
Score = 30.3 bits (65), Expect = 6.2
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 13/135 (9%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W RV + + L+ + E + L NW+ EE+L L +V
Sbjct: 5144 LGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNWMEAQEERLKTLQKPESVI 5203
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYD------LTMKTG--KHLKDKAPKGDE-----NP 354
K+ L ++ + LA K A D LT+++G L+D A + DE +
Sbjct: 5204 SVQKL---LLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASRIDELFQKRSS 5260
Query: 355 LKTMITDMKTKWTTV 399
+ T + +KT +V
Sbjct: 5261 VLTQVNQLKTSMQSV 5275
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 6642 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 6701
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 6702 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 6754
>AB023228-1|BAA76855.3| 3541|Homo sapiens KIAA1011 protein protein.
Length = 3541
Score = 53.2 bits (122), Expect = 8e-07
Identities = 36/198 (18%), Positives = 77/198 (38%), Gaps = 4/198 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ + ++ +W + K L K ++ + L WL ++ L+ +
Sbjct: 1548 LEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWKEQ 1607
Query: 202 A--TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
+ D D I+ +N EF K + K + G L + D L+ +
Sbjct: 1608 SLNVSQDLDTIRSNINNFFEFSKEVDEKSSLKTAVISIGNQLLH-LKETDTATLRASLAQ 1666
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVH--GDLD 549
+ KWT + ++ D Q KL + + + A++ ++ W + VH
Sbjct: 1667 FEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSAS 1726
Query: 550 TVMALIEQHKQFEEDLHF 603
V L+++HK+F ++ +
Sbjct: 1727 QVKHLLQKHKEFRMEMDY 1744
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 2626 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 2684
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 2685 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 2744
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 2745 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 2785
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 2746 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 2803
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 2804 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 2863
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 2864 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 2894
Score = 39.5 bits (88), Expect = 0.010
Identities = 28/167 (16%), Positives = 68/167 (40%), Gaps = 3/167 (1%)
Frame = +1
Query: 1 QKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQ 180
++ D ++ L + +W ++++ + L E +++W+N E Q
Sbjct: 1653 KETDTATLRASLAQFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQ 1712
Query: 181 LDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKD---KAPKGDEN 351
+S + + ++K L KH+EF+ + KQ D ++ L ++ + +
Sbjct: 1713 TSDEDSVHSPSSASQVKHLLQKHKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERT 1772
Query: 352 PLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +M +W V + + LE+ L + ++ + L +W
Sbjct: 1773 EFAEHLGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNW 1819
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 2849 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 2908
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 2909 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 2948
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 2516 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 2575
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 2576 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 2629
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 2630 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 2671
Score = 31.1 bits (67), Expect = 3.6
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 13/135 (9%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W RV + + L+ + E + L NWL EE+L L +V
Sbjct: 1778 LGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNWLEAQEERLKTLQKPESVI 1837
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYD------LTMKTG--KHLKDKAPKGDE-----NP 354
K+ L ++ + LA K A D LT+++G L+D A + DE +
Sbjct: 1838 SVQKL---LLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASRIDELFQKRSS 1894
Query: 355 LKTMITDMKTKWTTV 399
+ T + +KT +V
Sbjct: 1895 VLTQVNQLKTSMQSV 1909
Score = 30.3 bits (65), Expect = 6.2
Identities = 26/130 (20%), Positives = 57/130 (43%)
Frame = +1
Query: 28 NLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEAT 207
NL++ Q ++++V ++ RT L+ + +E+SD+ + W+ T L A
Sbjct: 392 NLMIPFQ-QYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLL------AN 444
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTK 387
D D ++ + Q AL + ++L L+D + + + L I ++ +
Sbjct: 445 PADYDSLRTLSHHASTVQMALEDSEQKHNLLHSIFMDLEDLSIIFETDELTQSIQELSNQ 504
Query: 388 WTTVCSKAVD 417
T + K ++
Sbjct: 505 VTALQQKIME 514
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 3299 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 3358
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 3359 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 3411
>X14298-1|CAA32479.1| 3685|Homo sapiens protein ( Human mRNA for
dystrophin. ).
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 39.5 bits (88), Expect = 0.010
Identities = 23/135 (17%), Positives = 58/135 (42%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAFEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>M18533-1|AAA53189.1| 3685|Homo sapiens dystrophin protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 36.3 bits (80), Expect = 0.095
Identities = 23/96 (23%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P ++ E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVQ-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>L05642-1|AAA74506.1| 428|Homo sapiens dystrophin protein.
Length = 428
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 42 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 99
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 100 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 159
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 160 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 189
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 148 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 205
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 206 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 265
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 266 WLCTRLNGKCKTLEE 280
Score = 36.7 bits (81), Expect = 0.072
Identities = 22/113 (19%), Positives = 48/113 (42%)
Frame = +1
Query: 259 QKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEE 438
Q +L +Q T K + KAP ++ +++ +W + S+ V+ +KLEE
Sbjct: 3 QSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRWKKLSSQLVEHCQKLEE 62
Query: 439 ALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+ + ++ + L W + + P GD + + ++Q + D+
Sbjct: 63 QMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDI 115
>AL451144-4|CAI39566.1| 3685|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>AL139278-1|CAI42991.1| 3685|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>AL109609-3|CAI42950.1| 3685|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>AL096699-2|CAI42225.1| 3685|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>AL031643-3|CAI43058.1| 3685|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>AL031542-2|CAI42229.1| 3685|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 3685
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/150 (18%), Positives = 73/150 (48%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
++ RW+++ S+ E + L+ + ++ + L W+ E + L + + D +
Sbjct: 1025 IEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKE--EWPALGDSE 1082
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+K++L + R + + QP+ + + G+ +K++A + L+T + ++ T+W +C
Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMC 1142
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+ L+ L + + +S + +W
Sbjct: 1143 QQVYARKEALKGGLEKTVSLQKDLSEMHEW 1172
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 2665 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 2724
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 2725 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 2784
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 2785 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 2844
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 2845 NDVHRAFKREL 2855
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 912 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 969
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 970 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 1029
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 1030 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 1089
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 1090 QCRLLVSDI 1098
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/159 (20%), Positives = 66/159 (41%)
Frame = +1
Query: 16 ILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN 195
+ ++ L + +WE+V +R D ++ + F WL E E+ L +
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQ 2131
Query: 196 SEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITD 375
K K L +E Q + +Q TG+ + ++ K D + L+ +
Sbjct: 2132 IPENWEHA-KYKWYL---KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGS 2187
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W VC + DR+++LEE +F+ ++ + W
Sbjct: 2188 LNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW 2226
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 351 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 408
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 409 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 466
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 467 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 500
Score = 40.3 bits (90), Expect = 0.006
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 4 KQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL 183
K D +++ L S+ RW+ V + ++R + L+ EF N + WL E + +
Sbjct: 2175 KTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEA-DNI 2233
Query: 184 DQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAP--KGDENPL 357
+ E ++K++L + + + L +Q +TG + AP +++ L
Sbjct: 2234 ASIPLEP--GKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKL 2291
Query: 358 KTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSAL 483
+ + +W V ++Q ++E + GQ + + L
Sbjct: 2292 ENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDL 2333
Score = 39.9 bits (89), Expect = 0.008
Identities = 23/135 (17%), Positives = 59/135 (43%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W+ + + R AL G ++ + + W+ + EE+ L +
Sbjct: 1131 LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY--LERDFEYK 1188
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWT 393
PD++++ + + + ++ K+ L ++ + +AP + LK + + T +
Sbjct: 1189 TPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQ 1248
Query: 394 TVCSKAVDRQRKLEE 438
+C++ + + LEE
Sbjct: 1249 WLCTRLNGKCKTLEE 1263
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 430 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 487
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 488 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 547
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 548 EDRWVLLQDILL 559
Score = 37.9 bits (84), Expect = 0.031
Identities = 24/96 (25%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P +K E + A+ +KQP
Sbjct: 2328 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVK-------ETEIAVQAKQPDV 2379
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 2380 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 2413
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 2771 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 2827
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 2828 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 2868
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 2549 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 2608
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 2609 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 2666
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 2667 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 2704
>BC150141-1|AAI50142.1| 1243|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 1243
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 205 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 264
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 265 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 324
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 325 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 384
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 385 NDVHRAFKREL 395
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 311 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 367
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 368 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 89 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 148
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 149 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 206
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 207 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 244
>BC127103-1|AAI27104.2| 1225|Homo sapiens DMD protein protein.
Length = 1225
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 205 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 264
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 265 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 324
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 325 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 384
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 385 NDVHRAFKREL 395
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 311 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 367
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 368 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 89 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 148
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 149 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 206
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 207 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 244
>AB208836-1|BAD92073.1| 1392|Homo sapiens dystrophin Dp427c isoform
variant protein.
Length = 1392
Score = 52.4 bits (120), Expect = 1e-06
Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 5/191 (2%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQL----DQLNSEAT 207
++ W + + +ER AL+ + ++F + WL E E D E
Sbjct: 367 NINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERL 426
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAY-DLTMKTGKHLKDKAPKGDENPLKTMITDMKT 384
+ D +K+ + + ++ Q + + Y +L + K L+ D L+ + +M
Sbjct: 427 LEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNF 486
Query: 385 KWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMAL 564
KW+ + K+++ + LE + + ++ LL W AP+ GD V
Sbjct: 487 KWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQ 546
Query: 565 IEQHKQFEEDL 597
+ H+ F+ +L
Sbjct: 547 NDVHRAFKREL 557
Score = 37.1 bits (82), Expect = 0.054
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D +L++ L ++ +W + KS L+ + K L+ WL + D+
Sbjct: 473 DAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DE 529
Query: 190 LNSEATV-NDPDKIKQRLNKHREFQKALASKQPAYDLTMKT 309
L+ +A + D ++++ + HR F++ L +K+P T++T
Sbjct: 530 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 570
Score = 36.3 bits (80), Expect = 0.095
Identities = 23/96 (23%), Positives = 46/96 (47%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
K+ ++ + N+L+ WL+ QL+ N + P ++ E + A+ +KQP
Sbjct: 30 KKLEDLEEQLNHLLLWLSPIRNQLEIYN-QPNQEGPFDVQ-------ETEIAVQAKQPDV 81
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
+ + G+HL + P P+K + D+ ++W V
Sbjct: 82 EEILSKGQHLYKEKPA--TQPVKRKLEDLSSEWKAV 115
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/158 (16%), Positives = 61/158 (38%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
+I + + +Q++W+ V R + L+ K++ ++ + L + +L+
Sbjct: 251 IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKE 310
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D I++++ + ++ K L Q D+ L D + + ++
Sbjct: 311 GPYT--VDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENI 368
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
W ++ + +R+ LEE QF + L W
Sbjct: 369 NASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAW 406
>AK094883-1|BAC04449.1| 775|Homo sapiens protein ( Homo sapiens
cDNA FLJ37564 fis, clone BRCOC2000816, weakly similar to
Homo sapiens mRNA for actin binding protein ABP620. ).
Length = 775
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/158 (19%), Positives = 70/158 (44%), Gaps = 1/158 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + H +E + ++ L+ + ++ + + +M WL + + +
Sbjct: 315 IKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQT 374
Query: 202 ATVNDPDKIKQRLNKHREFQKALASK-QPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
D + +K ++ +++ F+ L +L K + L++ + K M+T++
Sbjct: 375 PAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEI 434
Query: 379 KTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+KW + +DRQ+KLEE+ QF+ + L W
Sbjct: 435 DSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQW 472
Score = 50.4 bits (115), Expect = 5e-06
Identities = 35/194 (18%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
++K L +V +W+ + + ++R +D ++ ++ + +L + L++ + +L +S
Sbjct: 537 IVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLS--SS 594
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD-ENPLKTMITD 375
A PD + Q+L ++ ++ + ++ + + L + + L +
Sbjct: 595 LAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEG 654
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
+ + V KA + + L+ A S QF+ W P+ LD +
Sbjct: 655 ILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVL 714
Query: 556 MALIEQHKQFEEDL 597
+LI+ HK F + L
Sbjct: 715 ESLIKDHKDFSKTL 728
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/158 (18%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 25 KNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEA 204
K +L + +W+ + + +R + L+ +F + L WL E E + L +
Sbjct: 428 KQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLS 487
Query: 205 TVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD---ENPLKTMITD 375
DP+ + + + + + A+++P Y+ G+ + + P D +K +
Sbjct: 488 I--DPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSR-PGEDPSLHGIVKEQLAA 544
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLD 489
+ KW ++ + DR +++A++ S Q++ + +L D
Sbjct: 545 VTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSD 582
>AF233523-1|AAF65317.1| 3674|Homo sapiens beta V spectrin protein.
Length = 3674
Score = 50.8 bits (116), Expect = 4e-06
Identities = 46/194 (23%), Positives = 85/194 (43%), Gaps = 3/194 (1%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
++ L S+Q +W R+ +S +R R L + +E+ LM W+ E S
Sbjct: 1285 VREQLQSIQAQWTRLQGRSEQRRRQLLASL-QLQEWKQDVAELMQWMEEKGLMAAHEPSG 1343
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
A N I Q L +H + L + + + + G+ L + P G E+ ++T + ++
Sbjct: 1344 ARRN----ILQTLKRHEAAESELLATRRHVEALQQVGRELLSRRPCGQED-IQTRLQGLR 1398
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEG---DAPVHGDLDT 552
+KW + K +R +L++A GQ + + L D EG + DL +
Sbjct: 1399 SKWEALNRKMTERGDELQQA----GQQEQLLRQLQD-AKEQLEQLEGALQSSETGQDLRS 1453
Query: 553 VMALIEQHKQFEED 594
L ++H+Q E +
Sbjct: 1454 SQRLQKRHQQLESE 1467
Score = 33.1 bits (72), Expect = 0.88
Identities = 36/185 (19%), Positives = 78/185 (42%)
Frame = +1
Query: 43 VQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPD 222
V W ++ S++ +R ALD +A++ M L+ Q+D + P
Sbjct: 2448 VAESWWQLRSRAQKRREALD-ALHQAQKLQAMLQELLVSAQRLRAQMD---TSPAPRSPV 2503
Query: 223 KIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVC 402
+ ++ L +H+E + L S + L TG+ L A + ++ ++ ++ + +++
Sbjct: 2504 EARRMLEEHQECKAELDSWTDSISLARSTGQQLL-TAGHPFSSDIRQVLAGLEQELSSLE 2562
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQ 582
+ Q +L++AL F ++ + W + + L + L+ +HK
Sbjct: 2563 GAWQEHQLQLQQALELQ-LFLSSVEKMERWLCSKEDSLASEG-LWDPLAPMEPLLWKHKM 2620
Query: 583 FEEDL 597
E DL
Sbjct: 2621 LEWDL 2625
>X06178-1|CAA29544.1| 655|Homo sapiens DMD protein.
Length = 655
Score = 50.0 bits (114), Expect = 7e-06
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 2/189 (1%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAK--EFSDMWNNLMNWLNETEEQLDQLNSEATV 210
V+ + +++V S R + L F + + + + W+ ++E +L + +V
Sbjct: 428 VAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSI--PQLSV 485
Query: 211 NDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKW 390
D + ++QRL + + Q +L +Q T K + KAP ++ +++ +W
Sbjct: 486 TDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRW 545
Query: 391 TTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIE 570
+ S+ V+ +KLEE + + ++ + L W + + P GD + + ++
Sbjct: 546 KKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLK 605
Query: 571 QHKQFEEDL 597
Q + D+
Sbjct: 606 QCRLLVSDI 614
>BX538095-1|CAD98013.1| 1287|Homo sapiens hypothetical protein
protein.
Length = 1287
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 380 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 438
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 439 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 498
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 499 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 539
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 500 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 557
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 558 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 617
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 618 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 648
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 603 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 662
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 663 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 702
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 270 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 329
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 330 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 383
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 384 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 425
>AL080133-1|CAB45729.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 199 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 257
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 258 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 317
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 318 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 358
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 319 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 376
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 377 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 436
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 437 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 467
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 422 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 481
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 482 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 521
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 89 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 148
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 149 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 202
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 203 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 244
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 849 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 908
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 909 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 961
>AK090430-1|BAC03411.1| 1752|Homo sapiens FLJ00347 protein protein.
Length = 1752
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 4/161 (2%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I + L + RW+ + R + L F ++ +NL WL E +L +
Sbjct: 860 IDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVV 918
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMI 369
V D +I++RL + ++ Q+ + + H D E + ++
Sbjct: 919 YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTT 978
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ +W +C+ +++R+ K+EE +F D S DW
Sbjct: 979 RSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDW 1019
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 980 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 1037
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 1038 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 1097
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 1098 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 1128
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 1083 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 1142
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 1143 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 1182
Score = 32.3 bits (70), Expect = 1.5
Identities = 30/162 (18%), Positives = 68/162 (41%)
Frame = +1
Query: 7 QDVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLD 186
+DV+++K + + +WE + + A R + ++ F++ L WL + E ++
Sbjct: 750 EDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVL 809
Query: 187 QLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTM 366
Q ++ ++ +++ ++L K + L S+ + G L + K +
Sbjct: 810 Q-TADISI---EEMIEKLQKDCMEEINLFSENKLQ--LKQMGDQLIKASNKSRAAEIDDK 863
Query: 367 ITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ + +W + R +KL+E + Q MS L W
Sbjct: 864 LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTW 905
Score = 30.3 bits (65), Expect = 6.2
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 13/135 (9%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L + +W RV + + L+ + E + L NW+ EE+L L +V
Sbjct: 12 LGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNWMEAQEERLKTLQKPESVI 71
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYD------LTMKTG--KHLKDKAPKGDE-----NP 354
K+ L ++ + LA K A D LT+++G L+D A + DE +
Sbjct: 72 SVQKL---LLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASRIDELFQKRSS 128
Query: 355 LKTMITDMKTKWTTV 399
+ T + +KT +V
Sbjct: 129 VLTQVNQLKTSMQSV 143
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 1510 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 1569
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 1570 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 1622
>M61877-1|AAA60577.1| 2429|Homo sapiens erythroid alpha spectrin
protein.
Length = 2429
Score = 48.0 bits (109), Expect = 3e-05
Identities = 45/186 (24%), Positives = 79/186 (42%), Gaps = 1/186 (0%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+V R+ V +A L + + F D+ ++ +W+ EE+L +++S+ D
Sbjct: 1689 NVNKRFLNVQELAAAHHEKLKEAYALFQFFQDL-DDEESWI---EEKLIRVSSQDYGRDL 1744
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
++ L KH+ + L + +PA + + LKDKA G E ++ + W +
Sbjct: 1745 QGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEE-IQLRLAQFVEHWEKL 1803
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-LDTVMALIEQH 576
A R KLEE+L Y ++A GD GD L +L+ +H
Sbjct: 1804 KELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDC---GDTLAATQSLLMKH 1860
Query: 577 KQFEED 594
+ E D
Sbjct: 1861 EALEND 1866
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/216 (22%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + R + + K+A R R L K + D ++L NW+N+ ++ D +
Sbjct: 553 IKAIRDGLLARRDALREKAATRRRLLKESLLLQKLYEDS-DDLKNWINKKKKLAD----D 607
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
D +K R+ K + F+K LA + + KTG+ + + +N + T ++++
Sbjct: 608 EDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDN-VTTRLSEVA 666
Query: 382 TKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSAL--LDWXXXXXXXXEGDAPV---- 534
+ W + + +L EA L + +D L ++W +G A V
Sbjct: 667 SLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLAEVQNRL 726
Query: 535 --HGDLDTVMALIEQHKQFEEDLHFARAADAVRHQD 636
HG L++ +A + DL A + + H D
Sbjct: 727 RKHGLLESAVAARQDQVDILTDL--AAYFEEIGHPD 760
Score = 41.9 bits (94), Expect = 0.002
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSA-ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
I L V RW+ + ++ ERT+ D+ K+F L W++E +
Sbjct: 1471 IATRLQRVLDRWKALKAQLIDERTKLGDYA--NLKQFYRDLEELEEWISE----MLPTAC 1524
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
+ + D I+++ KH+ F + + + G L +++ G+E +K + +
Sbjct: 1525 DESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIERSCDGNEEAMKEQLEQL 1584
Query: 379 KTKWTTVCSKAVDRQRKLEEA 441
K W + + D+ +KL EA
Sbjct: 1585 KEHWDHLLERTNDKGKKLNEA 1605
>M61826-1|AAA60994.1| 2429|Homo sapiens alpha-spectrin protein.
Length = 2429
Score = 48.0 bits (109), Expect = 3e-05
Identities = 45/186 (24%), Positives = 79/186 (42%), Gaps = 1/186 (0%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+V R+ V +A L + + F D+ ++ +W+ EE+L +++S+ D
Sbjct: 1689 NVNKRFLNVQELAAAHHEKLKEAYALFQFFQDL-DDEESWI---EEKLIRVSSQDYGRDL 1744
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
++ L KH+ + L + +PA + + LKDKA G E ++ + W +
Sbjct: 1745 QGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEE-IQLRLAQFVEHWEKL 1803
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-LDTVMALIEQH 576
A R KLEE+L Y ++A GD GD L +L+ +H
Sbjct: 1804 KELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDC---GDTLAATQSLLMKH 1860
Query: 577 KQFEED 594
+ E D
Sbjct: 1861 EALEND 1866
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/216 (22%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + R + + K+A R R L K + D ++L NW+N+ ++ D +
Sbjct: 553 IKAIRDGLLARRDALREKAATRRRLLKESLLLQKLYEDS-DDLKNWINKKKKLAD----D 607
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
D +K R+ K + F+K LA + + KTG+ + + +N + T ++++
Sbjct: 608 EDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDN-VTTRLSEVA 666
Query: 382 TKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSAL--LDWXXXXXXXXEGDAPV---- 534
+ W + + +L EA L + +D L ++W +G A V
Sbjct: 667 SLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLAEVQNRL 726
Query: 535 --HGDLDTVMALIEQHKQFEEDLHFARAADAVRHQD 636
HG L++ +A + DL A + + H D
Sbjct: 727 RKHGLLESAVAARQDQVDILTDL--AAYFEEIGHPD 760
Score = 41.9 bits (94), Expect = 0.002
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSA-ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
I L V RW+ + ++ ERT+ D+ K+F L W++E +
Sbjct: 1471 IATRLQRVLDRWKALKAQLIDERTKLGDYA--NLKQFYRDLEELEEWISE----MLPTAC 1524
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
+ + D I+++ KH+ F + + + G L +++ G+E +K + +
Sbjct: 1525 DESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIERSCDGNEEAMKEQLEQL 1584
Query: 379 KTKWTTVCSKAVDRQRKLEEA 441
K W + + D+ +KL EA
Sbjct: 1585 KEHWDHLLERTNDKGKKLNEA 1605
>AL353894-3|CAH73936.1| 2416|Homo sapiens spectrin, alpha,
erythrocytic 1 (elliptocytosis 2) protein.
Length = 2416
Score = 48.0 bits (109), Expect = 3e-05
Identities = 45/186 (24%), Positives = 79/186 (42%), Gaps = 1/186 (0%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+V R+ V +A L + + F D+ ++ +W+ EE+L +++S+ D
Sbjct: 1690 NVNKRFLNVQELAAAHHEKLKEAYALFQFFQDL-DDEESWI---EEKLIRVSSQDYGRDL 1745
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
++ L KH+ + L + +PA + + LKDKA G E ++ + W +
Sbjct: 1746 QGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEE-IQLRLAQFVEHWEKL 1804
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-LDTVMALIEQH 576
A R KLEE+L Y ++A GD GD L +L+ +H
Sbjct: 1805 KELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDC---GDTLAATQSLLMKH 1861
Query: 577 KQFEED 594
+ E D
Sbjct: 1862 EALEND 1867
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/216 (22%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + R + + K+A R R L K + D ++L NW+N+ ++ D +
Sbjct: 553 IKAIRDGLLARRDALREKAATRRRLLKESLLLQKLYEDS-DDLKNWINKKKKLAD----D 607
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
D +K R+ K + F+K LA + + KTG+ + + +N + T ++++
Sbjct: 608 EDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDN-VTTRLSEVA 666
Query: 382 TKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSAL--LDWXXXXXXXXEGDAPV---- 534
+ W + + +L EA L + +D L ++W +G A V
Sbjct: 667 SLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLAEVQNRL 726
Query: 535 --HGDLDTVMALIEQHKQFEEDLHFARAADAVRHQD 636
HG L++ +A + DL A + + H D
Sbjct: 727 RKHGLLESAVAARQDQVDILTDL--AAYFEEIGHPD 760
>AL353894-2|CAH73937.1| 2419|Homo sapiens spectrin, alpha,
erythrocytic 1 (elliptocytosis 2) protein.
Length = 2419
Score = 48.0 bits (109), Expect = 3e-05
Identities = 45/186 (24%), Positives = 79/186 (42%), Gaps = 1/186 (0%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
+V R+ V +A L + + F D+ ++ +W+ EE+L +++S+ D
Sbjct: 1690 NVNKRFLNVQELAAAHHEKLKEAYALFQFFQDL-DDEESWI---EEKLIRVSSQDYGRDL 1745
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
++ L KH+ + L + +PA + + LKDKA G E ++ + W +
Sbjct: 1746 QGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEE-IQLRLAQFVEHWEKL 1804
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-LDTVMALIEQH 576
A R KLEE+L Y ++A GD GD L +L+ +H
Sbjct: 1805 KELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDC---GDTLAATQSLLMKH 1861
Query: 577 KQFEED 594
+ E D
Sbjct: 1862 EALEND 1867
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/216 (22%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
IK + + R + + K+A R R L K + D ++L NW+N+ ++ D +
Sbjct: 553 IKAIRDGLLARRDALREKAATRRRLLKESLLLQKLYEDS-DDLKNWINKKKKLAD----D 607
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
D +K R+ K + F+K LA + + KTG+ + + +N + T ++++
Sbjct: 608 EDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDN-VTTRLSEVA 666
Query: 382 TKWTTVCSKAVDRQRKLEEA---LLYSGQFKDAMSAL--LDWXXXXXXXXEGDAPV---- 534
+ W + + +L EA L + +D L ++W +G A V
Sbjct: 667 SLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLAEVQNRL 726
Query: 535 --HGDLDTVMALIEQHKQFEEDLHFARAADAVRHQD 636
HG L++ +A + DL A + + H D
Sbjct: 727 RKHGLLESAVAARQDQVDILTDL--AAYFEEIGHPD 760
>AB033077-1|BAA86565.1| 1483|Homo sapiens KIAA1251 protein protein.
Length = 1483
Score = 46.8 bits (106), Expect = 7e-05
Identities = 29/158 (18%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 19 LIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
L+K+ L R+ + SK L+ + +F + ++L W+ E +++L S
Sbjct: 1034 LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLS 1093
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK--DKAPKGDENPLKTMIT 372
+ +DP ++++L ++ Q+ LA Q + K + + + P D ++
Sbjct: 1094 DTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTD 1153
Query: 373 DMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALL 486
+ + + ++ +R L++A+ S ++++ +LL
Sbjct: 1154 SILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLL 1191
>BX640974-1|CAE45988.1| 899|Homo sapiens hypothetical protein
protein.
Length = 899
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 104 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 161
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 162 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 221
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 222 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 252
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 4/140 (2%)
Frame = +1
Query: 85 RTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQK 264
R + L F ++ +NL WL E +L + V D +I++RL + ++ Q+
Sbjct: 5 RVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVVYDVCDDQEIQKRLAEQQDLQR 63
Query: 265 ALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMITDMKTKWTTVCSKAVDRQRKL 432
+ + H D E + ++ + +W +C+ +++R+ K+
Sbjct: 64 DIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRMKI 123
Query: 433 EEALLYSGQFKDAMSALLDW 492
EE +F D S DW
Sbjct: 124 EETWRLWQKFLDDYSRFEDW 143
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 207 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 266
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 267 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 306
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 657 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 716
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 717 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 769
>AK074055-1|BAB84881.1| 878|Homo sapiens FLJ00126 protein protein.
Length = 878
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/151 (19%), Positives = 61/151 (40%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+ RW + + S ER ++ ++ ++F D ++ +WL E NS +
Sbjct: 105 SLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLY-- 162
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTV 399
K+ L + FQ+ + + +L K + L + + LK M+ + +W +
Sbjct: 163 TSAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNL 222
Query: 400 CSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+ R+L +F+ ++L W
Sbjct: 223 QRRVTAVLRRLRHFTNQREEFEGTRESILVW 253
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/144 (21%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Frame = +1
Query: 73 KSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHR 252
KS R + L F ++ +NL WL E +L + V D +I++RL + +
Sbjct: 2 KSYRRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK-PVVYDVCDDQEIQKRLAEQQ 60
Query: 253 EFQKALASKQPAYDLTMKTGK---HLKDKAPKGDE-NPLKTMITDMKTKWTTVCSKAVDR 420
+ Q+ + + H D E + ++ + +W +C+ +++R
Sbjct: 61 DLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMER 120
Query: 421 QRKLEEALLYSGQFKDAMSALLDW 492
+ K+EE +F D S DW
Sbjct: 121 RMKIEETWRLWQKFLDDYSRFEDW 144
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 208 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 267
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 268 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 307
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 635 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 694
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 695 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 747
>M19725-1|AAA59904.1| 475|Homo sapiens SPTAN1 protein.
Length = 475
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Frame = +1
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
+ SE D ++ KH+ + LA+ +PA + TGK L D G E ++ +
Sbjct: 17 VGSEDYGRDLTGVQNLRKKHKRLEGRLAAHEPAIQGVLDTGKKLTDDNTIGKEE-IQQRL 75
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGD-L 546
W + A R ++LEE+L Y QF + W + +GD L
Sbjct: 76 AQFVEHWKELTELAAARGQRLEESLEYQ-QFVANVEEEEAWINEKMTLVASED--YGDTL 132
Query: 547 DTVMALIEQHKQFEED 594
+ L+++H+ FE D
Sbjct: 133 AAIQGLLKKHEAFETD 148
>BC036103-1|AAH36103.1| 772|Homo sapiens DMD protein protein.
Length = 772
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 343 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 400
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 401 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 458
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 459 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 492
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 422 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 479
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 480 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 539
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 540 EDRWVLLQDILL 551
>AL451144-5|CAI39567.1| 719|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 719
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 347 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 404
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 405 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 462
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 463 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 496
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 426 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 483
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 484 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 543
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 544 EDRWVLLQDILL 555
>AL451144-1|CAI39563.1| 772|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 772
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 343 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 400
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 401 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 458
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 459 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 492
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 422 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 479
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 480 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 539
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 540 EDRWVLLQDILL 551
>AL096699-3|CAI42226.1| 719|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 719
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 347 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 404
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 405 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 462
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 463 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 496
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 426 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 483
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 484 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 543
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 544 EDRWVLLQDILL 555
>AL096699-1|CAI42224.1| 772|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 772
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 343 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 400
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 401 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 458
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 459 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 492
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 422 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 479
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 480 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 539
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 540 EDRWVLLQDILL 551
>AL050305-1|CAI42099.1| 772|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 772
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 343 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 400
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 401 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 458
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 459 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 492
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 422 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 479
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 480 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 539
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 540 EDRWVLLQDILL 551
>AL049643-1|CAI43007.1| 719|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 719
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 347 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 404
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 405 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 462
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 463 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 496
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 426 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 483
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 484 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 543
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 544 EDRWVLLQDILL 555
>AL031542-3|CAI42230.1| 719|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 719
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 347 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 404
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 405 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 462
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 463 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 496
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 426 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 483
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 484 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 543
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 544 EDRWVLLQDILL 555
>AL031542-1|CAI42228.1| 772|Homo sapiens dystrophin (muscular
dystrophy, Duchenne and Becker types) protein.
Length = 772
Score = 44.0 bits (99), Expect = 5e-04
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 148 LMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHL-- 321
+++WL E+ L Q E + ND + +K + + H + L + Q ++ G L
Sbjct: 343 VLSWLLSAEDTL-QAQGEIS-NDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIG 400
Query: 322 KDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXX 501
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 401 TGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTK 458
Query: 502 XXXXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 459 TEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 492
Score = 39.5 bits (88), Expect = 0.010
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 422 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 479
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 480 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 539
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 540 EDRWVLLQDILL 551
>M11049-1|AAA60569.1| 237|Homo sapiens SPTA1 protein.
Length = 237
Score = 41.9 bits (94), Expect = 0.002
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSA-ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNS 198
I L V RW+ + ++ ERT+ D+ K+F L W++E +
Sbjct: 21 IATRLQRVLDRWKALKAQLIDERTKLGDYA--NLKQFYRDLEELEEWISE----MLPTAC 74
Query: 199 EATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDM 378
+ + D I+++ KH+ F + + + G L +++ G+E +K + +
Sbjct: 75 DESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIERSCDGNEEAMKEQLEQL 134
Query: 379 KTKWTTVCSKAVDRQRKLEEA 441
K W + + D+ +KL EA
Sbjct: 135 KEHWDHLLERTNDKGKKLNEA 155
>X06179-1|CAA29545.1| 209|Homo sapiens DMD protein.
Length = 209
Score = 39.9 bits (89), Expect = 0.008
Identities = 27/132 (20%), Positives = 57/132 (43%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RWE + S E+ L + + + L +WL +TEE+ ++ E D + +K
Sbjct: 27 RWECLRVASMEKQSNLHRVLMDLQ--NQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLK 84
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKA 411
+++ +H+ Q+ L +Q + + + + L+ + + +W +C
Sbjct: 85 RQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWT 144
Query: 412 VDRQRKLEEALL 447
DR L++ LL
Sbjct: 145 EDRWVLLQDTLL 156
Score = 30.3 bits (65), Expect = 6.2
Identities = 19/92 (20%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 328 KAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXX 507
K + +E ++ + + ++W + ++++Q L L+ K + L DW
Sbjct: 8 KLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQK--LKELNDWLTKTE 65
Query: 508 XXXEG--DAPVHGDLDTVMALIEQHKQFEEDL 597
+ P+ DL+ + ++QHK +EDL
Sbjct: 66 ERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDL 97
>AF083131-1|AAF98241.1| 246|Homo sapiens unknown protein.
Length = 246
Score = 38.3 bits (85), Expect = 0.023
Identities = 30/160 (18%), Positives = 74/160 (46%), Gaps = 5/160 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ V+ + + +R ALD ++ +F D + ++ L E+L Q S
Sbjct: 9 IQEKYVAADTLYSHIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSI 68
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDEN----PLKTMI 369
+ + +KIK+++++++ + QP Y+ + G+ + ++ D++ ++ +
Sbjct: 69 SA--EVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKL 126
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF-KDAMSALL 486
M W + + +R+ KL + + + +F D MS ++
Sbjct: 127 DQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIV 166
>AY061757-1|AAL33800.1| 763|Homo sapiens nesprin-2 beta protein.
Length = 763
Score = 36.7 bits (81), Expect = 0.072
Identities = 26/139 (18%), Positives = 55/139 (39%)
Frame = +1
Query: 76 SAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHRE 255
S ER ++ ++ ++F D ++ +WL E NS + K+ L +
Sbjct: 2 SMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYT--SAKEELKRFEA 59
Query: 256 FQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLE 435
FQ+ + + +L K + L + + LK M+ + +W + + R+L
Sbjct: 60 FQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNLQRRVTAVLRRLR 119
Query: 436 EALLYSGQFKDAMSALLDW 492
+F+ ++L W
Sbjct: 120 HFTNQREEFEGTRESILVW 138
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K ++ RW+ + + R L H + +EF +++ WL E + QL +
Sbjct: 93 LKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHF 152
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ + DK++Q LN FQ+ + D + G+ L K+
Sbjct: 153 SESDADDKMRQ-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 192
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 520 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 579
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 580 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 632
>M96803-1|AAA60580.1| 2364|Homo sapiens beta-spectrin protein.
Length = 2364
Score = 35.1 bits (77), Expect = 0.22
Identities = 29/148 (19%), Positives = 63/148 (42%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVND 216
++VQ ++ ++ ER L KE +F+ + + W+ E ++ S ++
Sbjct: 1461 LTVQTKFMELLEPLNERKHNL-LASKEIHQFNRDVEDEILWVGE---RMPLATSTDHGHN 1516
Query: 217 PDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTT 396
++ + K++ QK + QP D + +++ + ++ + D+K W
Sbjct: 1517 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGL 1576
Query: 397 VCSKAVDRQRKLEEALLYSGQFKDAMSA 480
+ + R R+LEEA + DA A
Sbjct: 1577 LIEETEKRHRRLEEAHRAQQYYFDAAEA 1604
Score = 30.7 bits (66), Expect = 4.7
Identities = 24/110 (21%), Positives = 46/110 (41%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
++ ++F L W+NE ++ + N + + KH+ F LAS +
Sbjct: 1275 RDLQKFLQDCQELSLWINEKMLTAQDMSYDEARN----LHSKWLKHQAFMAELASNKEWL 1330
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEA 441
D K G L + P+ E +K +T + W + S + ++L +A
Sbjct: 1331 DKIEKEGMQLISEKPE-TEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDA 1379
>AF327441-1|AAO15362.1| 2155|Homo sapiens beta-spectrin 2 isoform 2
protein.
Length = 2155
Score = 35.1 bits (77), Expect = 0.22
Identities = 29/148 (19%), Positives = 63/148 (42%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVND 216
++VQ ++ ++ ER L KE +F+ + + W+ E ++ S ++
Sbjct: 1448 LTVQTKFMELLEPLNERKHNL-LASKEIHQFNRDVEDEILWVGE---RMPLATSTDHGHN 1503
Query: 217 PDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTT 396
++ + K++ QK + QP D + +++ + ++ + D+K W
Sbjct: 1504 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGL 1563
Query: 397 VCSKAVDRQRKLEEALLYSGQFKDAMSA 480
+ + R R+LEEA + DA A
Sbjct: 1564 LIEETEKRHRRLEEAHRAQQYYFDAAEA 1591
Score = 30.7 bits (66), Expect = 4.7
Identities = 24/110 (21%), Positives = 46/110 (41%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
++ ++F L W+NE ++ + N + + KH+ F LAS +
Sbjct: 1262 RDLQKFLQDCQELSLWINEKMLTAQDMSYDEARN----LHSKWLKHQAFMAELASNKEWL 1317
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEA 441
D K G L + P+ E +K +T + W + S + ++L +A
Sbjct: 1318 DKIEKEGMQLISEKPE-TEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDA 1366
>AC093110-1|AAY24229.1| 2314|Homo sapiens unknown protein.
Length = 2314
Score = 35.1 bits (77), Expect = 0.22
Identities = 29/148 (19%), Positives = 63/148 (42%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVND 216
++VQ ++ ++ ER L KE +F+ + + W+ E ++ S ++
Sbjct: 1411 LTVQTKFMELLEPLNERKHNL-LASKEIHQFNRDVEDEILWVGE---RMPLATSTDHGHN 1466
Query: 217 PDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTT 396
++ + K++ QK + QP D + +++ + ++ + D+K W
Sbjct: 1467 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGL 1526
Query: 397 VCSKAVDRQRKLEEALLYSGQFKDAMSA 480
+ + R R+LEEA + DA A
Sbjct: 1527 LIEETEKRHRRLEEAHRAQQYYFDAAEA 1554
Score = 32.7 bits (71), Expect = 1.2
Identities = 33/162 (20%), Positives = 65/162 (40%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
++ ++F L W+NE ++ + N + + KH+ F LAS +
Sbjct: 1225 RDLQKFLQDCQELSLWINEKMLTAQDMSYDEARN----LHSKWLKHQAFMAELASNKEWL 1280
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
D K G L + P+ E +K +T + W + S + ++L +A + F +
Sbjct: 1281 DKIEKEGMQLISEKPE-TEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDA-NKAELFTQS 1338
Query: 472 MSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+ L W + D DL +V L+++ + E +
Sbjct: 1339 CADLDKWLHGLESQIQSD-DYGKDLTSVNILLKKQQMLENQM 1379
>AB209748-1|BAD92985.1| 2377|Homo sapiens spectrin, beta,
non-erythrocytic 1 isoform 1 variant protein.
Length = 2377
Score = 35.1 bits (77), Expect = 0.22
Identities = 29/148 (19%), Positives = 63/148 (42%)
Frame = +1
Query: 37 VSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVND 216
++VQ ++ ++ ER L KE +F+ + + W+ E ++ S ++
Sbjct: 1474 LTVQTKFMELLEPLNERKHNL-LASKEIHQFNRDVEDEILWVGE---RMPLATSTDHGHN 1529
Query: 217 PDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTT 396
++ + K++ QK + QP D + +++ + ++ + D+K W
Sbjct: 1530 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGL 1589
Query: 397 VCSKAVDRQRKLEEALLYSGQFKDAMSA 480
+ + R R+LEEA + DA A
Sbjct: 1590 LIEETEKRHRRLEEAHRAQQYYFDAAEA 1617
Score = 32.7 bits (71), Expect = 1.2
Identities = 33/162 (20%), Positives = 65/162 (40%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
++ ++F L W+NE ++ + N + + KH+ F LAS +
Sbjct: 1288 RDLQKFLQDCQELSLWINEKMLTAQDMSYDEARN----LHSKWLKHQAFMAELASNKEWL 1343
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
D K G L + P+ E +K +T + W + S + ++L +A + F +
Sbjct: 1344 DKIEKEGMQLISEKPE-TEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDA-NKAELFTQS 1401
Query: 472 MSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+ L W + D DL +V L+++ + E +
Sbjct: 1402 CADLDKWLHGLESQIQSD-DYGKDLTSVNILLKKQQMLENQM 1442
>Z70281-2|CAO03505.1| 957|Homo sapiens dystrophin related protein 2
protein.
Length = 957
Score = 33.9 bits (74), Expect = 0.51
Identities = 17/74 (22%), Positives = 32/74 (43%)
Frame = +1
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
M W + K+ + + +LE +SG+ + + ++DW P+ GD+ V
Sbjct: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
Query: 556 MALIEQHKQFEEDL 597
E H F E++
Sbjct: 139 QQEKETHAAFMEEV 152
>Z70281-1|CAO03504.1| 353|Homo sapiens dystrophin related protein 2
protein.
Length = 353
Score = 33.9 bits (74), Expect = 0.51
Identities = 17/74 (22%), Positives = 32/74 (43%)
Frame = +1
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
M W + K+ + + +LE +SG+ + + ++DW P+ GD+ V
Sbjct: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
Query: 556 MALIEQHKQFEEDL 597
E H F E++
Sbjct: 139 QQEKETHAAFMEEV 152
>Z68331-3|CAI42016.2| 957|Homo sapiens dystrophin related protein 2
protein.
Length = 957
Score = 33.9 bits (74), Expect = 0.51
Identities = 17/74 (22%), Positives = 32/74 (43%)
Frame = +1
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
M W + K+ + + +LE +SG+ + + ++DW P+ GD+ V
Sbjct: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
Query: 556 MALIEQHKQFEEDL 597
E H F E++
Sbjct: 139 QQEKETHAAFMEEV 152
>U43519-1|AAC50538.1| 954|Homo sapiens dystrophin-related protein 2
protein.
Length = 954
Score = 33.9 bits (74), Expect = 0.51
Identities = 17/74 (22%), Positives = 32/74 (43%)
Frame = +1
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
M W + K+ + + +LE +SG+ + + ++DW P+ GD+ V
Sbjct: 76 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 135
Query: 556 MALIEQHKQFEEDL 597
E H F E++
Sbjct: 136 QQEKETHAAFMEEV 149
>U26396-1|AAB60364.1| 719|Homo sapiens alpha II spectrin protein.
Length = 719
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 51 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 106
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 107 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 156
>M24773-1|AAA52468.1| 920|Homo sapiens alpha-fodrin protein.
Length = 920
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 186 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 241
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 242 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 291
>M18627-1|AAA51702.1| 920|Homo sapiens SPTAN1 protein.
Length = 920
Score = 33.9 bits (74), Expect = 0.51
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
+K L + +WE + +K+++R + L+ + + F+D N +W+ E E + S
Sbjct: 186 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA-NEAESWMREKE---PIVGST 241
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDK-APKGDE 348
D D + L KH L++ + + + + + AP DE
Sbjct: 242 DYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDE 291
>BC111695-1|AAI11696.2| 954|Homo sapiens dystrophin related protein
2 protein.
Length = 954
Score = 33.9 bits (74), Expect = 0.51
Identities = 17/74 (22%), Positives = 32/74 (43%)
Frame = +1
Query: 376 MKTKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTV 555
M W + K+ + + +LE +SG+ + + ++DW P+ GD+ V
Sbjct: 76 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 135
Query: 556 MALIEQHKQFEEDL 597
E H F E++
Sbjct: 136 QQEKETHAAFMEEV 149
>AL357081-3|CAI41324.1| 675|Homo sapiens RP11-809I23.2 protein.
Length = 675
Score = 33.9 bits (74), Expect = 0.51
Identities = 31/173 (17%), Positives = 64/173 (36%), Gaps = 1/173 (0%)
Frame = +1
Query: 82 ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQ 261
E+ LD E +FS L +W+ + LD +D + R K
Sbjct: 370 EKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCH--PTSDKSVLDSRTLKLEALL 427
Query: 262 KALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEE 438
K+ + + G+ L++ +P+G ++ + +K W ++ S + + +LE
Sbjct: 428 SVKQEKEIQMKMIVTRGESVLQNTSPEGIPT-IQQQLQSVKDMWASLLSAGIRCKSQLEG 486
Query: 439 ALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
AL ++D + W H +L ++ + K E++
Sbjct: 487 ALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEV 539
Score = 29.9 bits (64), Expect = 8.2
Identities = 23/157 (14%), Positives = 70/157 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + + W+ S ++ AL++ + K+F + +WL++TE+ + + +S
Sbjct: 243 IQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHE-SSN 301
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ P K +++ K + + + +P + + + L + + + ++ +
Sbjct: 302 RLYDLPAKRREQ-QKLQSVLEEIHCYEPQLNRLKEKAQQLWE--GQAASKSFRHRVSQLS 358
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + ++ +L+ + QF + L DW
Sbjct: 359 SQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDW 395
>AL049548-6|CAI42747.1| 675|Homo sapiens RP11-809I23.2 protein.
Length = 675
Score = 33.9 bits (74), Expect = 0.51
Identities = 31/173 (17%), Positives = 64/173 (36%), Gaps = 1/173 (0%)
Frame = +1
Query: 82 ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQ 261
E+ LD E +FS L +W+ + LD +D + R K
Sbjct: 370 EKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCH--PTSDKSVLDSRTLKLEALL 427
Query: 262 KALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEE 438
K+ + + G+ L++ +P+G ++ + +K W ++ S + + +LE
Sbjct: 428 SVKQEKEIQMKMIVTRGESVLQNTSPEGIPT-IQQQLQSVKDMWASLLSAGIRCKSQLEG 486
Query: 439 ALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
AL ++D + W H +L ++ + K E++
Sbjct: 487 ALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEV 539
Score = 29.9 bits (64), Expect = 8.2
Identities = 23/157 (14%), Positives = 70/157 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + + W+ S ++ AL++ + K+F + +WL++TE+ + + +S
Sbjct: 243 IQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHE-SSN 301
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ P K +++ K + + + +P + + + L + + + ++ +
Sbjct: 302 RLYDLPAKRREQ-QKLQSVLEEIHCYEPQLNRLKEKAQQLWE--GQAASKSFRHRVSQLS 358
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + ++ +L+ + QF + L DW
Sbjct: 359 SQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDW 395
>AK056122-1|BAB71097.1| 560|Homo sapiens protein ( Homo sapiens
cDNA FLJ31560 fis, clone NT2RI2001409, weakly similar to
DYSTROPHIN. ).
Length = 560
Score = 33.9 bits (74), Expect = 0.51
Identities = 31/173 (17%), Positives = 64/173 (36%), Gaps = 1/173 (0%)
Frame = +1
Query: 82 ERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQ 261
E+ LD E +FS L +W+ + LD +D + R K
Sbjct: 352 EKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCH--PTSDKSVLDSRTLKLEALL 409
Query: 262 KALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEE 438
K+ + + G+ L++ +P+G ++ + +K W ++ S + + +LE
Sbjct: 410 SVKQEKEIQMKMIVTRGESVLQNTSPEGIPT-IQQQLQSVKDMWASLLSAGIRCKSQLEG 468
Query: 439 ALLYSGQFKDAMSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
AL ++D + W H +L ++ + K E++
Sbjct: 469 ALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEV 521
Score = 29.9 bits (64), Expect = 8.2
Identities = 23/157 (14%), Positives = 70/157 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + + W+ S ++ AL++ + K+F + +WL++TE+ + + +S
Sbjct: 225 IQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHE-SSN 283
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ P K +++ K + + + +P + + + L + + + ++ +
Sbjct: 284 RLYDLPAKRREQ-QKLQSVLEEIHCYEPQLNRLKEKAQQLWE--GQAASKSFRHRVSQLS 340
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + ++ +L+ + QF + L DW
Sbjct: 341 SQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDW 377
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 33.5 bits (73), Expect = 0.67
Identities = 16/77 (20%), Positives = 35/77 (45%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+R+ + R L+ K+ + + D + WL + + + D L S D + +
Sbjct: 866 RWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQDSLES-MKFGDSNTVM 924
Query: 232 QRLNKHREFQKALASKQ 282
+ LN+ + ++ K+
Sbjct: 925 RFLNEQKNLHSEISGKR 941
>AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein protein.
Length = 2319
Score = 33.5 bits (73), Expect = 0.67
Identities = 16/77 (20%), Positives = 35/77 (45%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+R+ + R L+ K+ + + D + WL + + + D L S D + +
Sbjct: 913 RWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQDSLES-MKFGDSNTVM 971
Query: 232 QRLNKHREFQKALASKQ 282
+ LN+ + ++ K+
Sbjct: 972 RFLNEQKNLHSEISGKR 988
>Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50
protein.
Length = 1318
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 257 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 315
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 316 NHQRTVR--EKERKLVDCHRELEK 337
>U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein.
Length = 1312
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 251 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 309
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 310 NHQRTVR--EKERKLVDCHRELEK 331
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 33.1 bits (72), Expect = 0.88
Identities = 16/77 (20%), Positives = 35/77 (45%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+R+ + R L+ K+ + + D + WL + + + D L S D + +
Sbjct: 866 RWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDRKRRQDSLES-MKFGDSNTVM 924
Query: 232 QRLNKHREFQKALASKQ 282
+ LN+ + ++ K+
Sbjct: 925 RFLNEQKNLHSEISGKR 941
>BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein.
Length = 949
Score = 33.1 bits (72), Expect = 0.88
Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 2/38 (5%)
Frame = +1
Query: 346 ENPLKTMITDMKTKWTTVCSKAV--DRQRKLEEALLYS 453
E+P + +++ KW +K + DRQRK+EE ++YS
Sbjct: 318 EHPFSAVKQELQRKWIEELNKQIEDDRQRKIEEKIIYS 355
>BC108282-1|AAI08283.1| 723|Homo sapiens RAD50 protein protein.
Length = 723
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 251 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 309
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 310 NHQRTVR--EKERKLVDCHRELEK 331
>BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein.
Length = 723
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 251 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 309
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 310 NHQRTVR--EKERKLVDCHRELEK 331
>BC062603-1|AAH62603.1| 557|Homo sapiens RAD50 protein protein.
Length = 557
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 251 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 309
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 310 NHQRTVR--EKERKLVDCHRELEK 331
>BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain
containing 66 protein.
Length = 831
Score = 33.1 bits (72), Expect = 0.88
Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 2/38 (5%)
Frame = +1
Query: 346 ENPLKTMITDMKTKWTTVCSKAV--DRQRKLEEALLYS 453
E+P + +++ KW +K + DRQRK+EE ++YS
Sbjct: 201 EHPFSAVKQELQRKWIEELNKQIEDDRQRKIEEKIIYS 238
>BC033900-1|AAH33900.1| 335|Homo sapiens NDE1 protein protein.
Length = 335
Score = 33.1 bits (72), Expect = 0.88
Identities = 22/100 (22%), Positives = 47/100 (47%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ ++E S+ + AL+ + K D + L + + L++ AT+
Sbjct: 75 LETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK-RATIM 133
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ +QRLN+ E L S+ + +++ + LKD+A
Sbjct: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
>BC001421-1|AAH01421.1| 335|Homo sapiens nudE nuclear distribution
gene E homolog 1 (A. nidulans) protein.
Length = 335
Score = 33.1 bits (72), Expect = 0.88
Identities = 22/100 (22%), Positives = 47/100 (47%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ ++E S+ + AL+ + K D + L + + L++ AT+
Sbjct: 75 LETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK-RATIM 133
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ +QRLN+ E L S+ + +++ + LKD+A
Sbjct: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
>AK000108-1|BAA90949.1| 335|Homo sapiens protein ( Homo sapiens
cDNA FLJ20101 fis, clone COL04655. ).
Length = 335
Score = 33.1 bits (72), Expect = 0.88
Identities = 22/100 (22%), Positives = 47/100 (47%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
L +++ ++E S+ + AL+ + K D + L + + L++ AT+
Sbjct: 75 LETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK-RATIM 133
Query: 214 DPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
+ +QRLN+ E L S+ + +++ + LKD+A
Sbjct: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
>AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein
protein.
Length = 1173
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 112 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 170
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 171 NHQRTVR--EKERKLVDCHRELEK 192
>AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein.
Length = 1312
Score = 33.1 bits (72), Expect = 0.88
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEA-KEFSDMWNNLMNWLNETEEQLDQL-- 192
+KN L ++H +++ E +ALD K+ K+ S++ + T+EQL+ L
Sbjct: 251 LKNRLKEIEHNLSKIMKLDNE-IKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYH 309
Query: 193 NSEATVNDPDKIKQRLNKHREFQK 264
N + TV +K ++ ++ HRE +K
Sbjct: 310 NHQRTVR--EKERKLVDCHRELEK 331
>S65762-1|AAB28324.1| 1252|Homo sapiens beta-fodrin protein.
Length = 1252
Score = 32.7 bits (71), Expect = 1.2
Identities = 33/162 (20%), Positives = 65/162 (40%)
Frame = +1
Query: 112 KEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAY 291
++ ++F L W+NE ++ + N + + KH+ F LAS +
Sbjct: 983 RDLQKFLQDCQELSLWINEKMLTAQDMSYDEARN----LHSKWLKHQAFMAELASNKEWL 1038
Query: 292 DLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQRKLEEALLYSGQFKDA 471
D K G L + P+ E +K +T + W + S + ++L +A + F +
Sbjct: 1039 DKIEKEGMQLISEKPE-TEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDA-NKAELFTQS 1096
Query: 472 MSALLDWXXXXXXXXEGDAPVHGDLDTVMALIEQHKQFEEDL 597
+ L W + D DL +V L+++ + E +
Sbjct: 1097 CADLDKWLHGLESQIQSD-DYGKDLTSVNILLKKQQMLENQM 1137
>BC150289-1|AAI50290.1| 1362|Homo sapiens Unknown (protein for
IMAGE:8860128) protein.
Length = 1362
Score = 32.3 bits (70), Expect = 1.5
Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
+ +V RW R+ + + ++ + L+ E W N + + E +DQL + +
Sbjct: 967 MTTVWQRWTRLRAVAQDQEKILEDAVDE-------WTGFNNKVKKATEMIDQLQDKLPGS 1019
Query: 214 DPDKIKQR-----LNKHREFQKALASKQPAYD-LTMKTGKHLKDKA--PKGDENPLKTMI 369
+K + L H F L +Q A L +T L+D A G+E PL I
Sbjct: 1020 SAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEI 1079
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEAL 444
T M+ + + K + +++ L
Sbjct: 1080 TAMQDRCLNMQEKVKTNGKLVKQEL 1104
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/151 (16%), Positives = 54/151 (35%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D L+K ++ RW ++ + + +E + LM W E + + +
Sbjct: 92 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 151
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ PD + L H L +KQ +K + + ++ +
Sbjct: 152 ALKQSP--PPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKAL 209
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF 462
+D ++ + R++ L +AL QF
Sbjct: 210 SDAQSHVNCLSDLVGQRRKYLNKALSEKTQF 240
>AY184205-1|AAO27773.1| 668|Homo sapiens nesprin-2 beta 2 protein.
Length = 668
Score = 32.3 bits (70), Expect = 1.5
Identities = 23/94 (24%), Positives = 42/94 (44%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ + + R L H + +EF +++ WL E + QL + + + DK++
Sbjct: 8 RWDNLQRRVTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMR 67
Query: 232 QRLNKHREFQKALASKQPAYDLTMKTGKHLKDKA 333
Q LN FQ+ + D + G+ L K+
Sbjct: 68 Q-LN---GFQQEITLNTNKIDQLIVFGEQLIQKS 97
Score = 29.9 bits (64), Expect = 8.2
Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 2/113 (1%)
Frame = +1
Query: 55 WERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQ 234
WE L + ++F + NL+ WL + + + + DP + +
Sbjct: 425 WEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLE 484
Query: 235 RLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGD--ENPLKTMITDMKTK 387
+ + +K L +QP D+ + L K D E K + + K K
Sbjct: 485 CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLK 537
>AL357081-2|CAI41323.1| 1362|Homo sapiens spectrin repeat containing,
nuclear envelope 1 protein.
Length = 1362
Score = 32.3 bits (70), Expect = 1.5
Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
+ +V RW R+ + + ++ + L+ E W N + + E +DQL + +
Sbjct: 967 MTTVWQRWTRLRAVAQDQEKILEDAVDE-------WTGFNNKVKKATEMIDQLQDKLPGS 1019
Query: 214 DPDKIKQR-----LNKHREFQKALASKQPAYD-LTMKTGKHLKDKA--PKGDENPLKTMI 369
+K + L H F L +Q A L +T L+D A G+E PL I
Sbjct: 1020 SAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEI 1079
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEAL 444
T M+ + + K + +++ L
Sbjct: 1080 TAMQDRCLNMQEKVKTNGKLVKQEL 1104
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/151 (16%), Positives = 54/151 (35%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D L+K ++ RW ++ + + +E + LM W E + + +
Sbjct: 92 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 151
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ PD + L H L +KQ +K + + ++ +
Sbjct: 152 ALKQSP--PPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKAL 209
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF 462
+D ++ + R++ L +AL QF
Sbjct: 210 SDAQSHVNCLSDLVGQRRKYLNKALSEKTQF 240
>AB033088-1|BAA86576.1| 1362|Homo sapiens KIAA1262 protein protein.
Length = 1362
Score = 32.3 bits (70), Expect = 1.5
Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +1
Query: 34 LVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVN 213
+ +V RW R+ + + ++ + L+ E W N + + E +DQL + +
Sbjct: 967 MTTVWQRWTRLRAVAQDQEKILEDAVDE-------WTGFNNKVKKATEMIDQLQDKLPGS 1019
Query: 214 DPDKIKQR-----LNKHREFQKALASKQPAYD-LTMKTGKHLKDKA--PKGDENPLKTMI 369
+K + L H F L +Q A L +T L+D A G+E PL I
Sbjct: 1020 SAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEI 1079
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEAL 444
T M+ + + K + +++ L
Sbjct: 1080 TAMQDRCLNMQEKVKTNGKLVKQEL 1104
Score = 29.9 bits (64), Expect = 8.2
Identities = 25/151 (16%), Positives = 54/151 (35%)
Frame = +1
Query: 10 DVILIKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQ 189
D L+K ++ RW ++ + + +E + LM W E + + +
Sbjct: 92 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 151
Query: 190 LNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMI 369
++ PD + L H L +KQ +K + + ++ +
Sbjct: 152 ALKQSP--PPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKAL 209
Query: 370 TDMKTKWTTVCSKAVDRQRKLEEALLYSGQF 462
+D ++ + R++ L +AL QF
Sbjct: 210 SDAQSHVNCLSDLVGQRRKYLNKALSEKTQF 240
>BC003542-1|AAH03542.2| 860|Homo sapiens M-phase phosphoprotein,
mpp8 protein.
Length = 860
Score = 31.9 bits (69), Expect = 2.0
Identities = 24/81 (29%), Positives = 39/81 (48%)
Frame = +1
Query: 145 NLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK 324
+L N + E DQ + P K K++L + E K+ A K GK LK
Sbjct: 126 SLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKA-----KAGK-LK 179
Query: 325 DKAPKGDENPLKTMITDMKTK 387
DK+ E+ L++++ D++TK
Sbjct: 180 DKSKPDLESSLESLVFDLRTK 200
>AL359457-4|CAI16671.1| 860|Homo sapiens M-phase phosphoprotein,
mpp protein.
Length = 860
Score = 31.9 bits (69), Expect = 2.0
Identities = 24/81 (29%), Positives = 39/81 (48%)
Frame = +1
Query: 145 NLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK 324
+L N + E DQ + P K K++L + E K+ A K GK LK
Sbjct: 126 SLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKA-----KAGK-LK 179
Query: 325 DKAPKGDENPLKTMITDMKTK 387
DK+ E+ L++++ D++TK
Sbjct: 180 DKSKPDLESSLESLVFDLRTK 200
>AL354808-3|CAI41002.1| 860|Homo sapiens M-phase phosphoprotein,
mpp protein.
Length = 860
Score = 31.9 bits (69), Expect = 2.0
Identities = 24/81 (29%), Positives = 39/81 (48%)
Frame = +1
Query: 145 NLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLK 324
+L N + E DQ + P K K++L + E K+ A K GK LK
Sbjct: 126 SLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKA-----KAGK-LK 179
Query: 325 DKAPKGDENPLKTMITDMKTK 387
DK+ E+ L++++ D++TK
Sbjct: 180 DKSKPDLESSLESLVFDLRTK 200
>X15495-1|CAA33518.1| 58|Homo sapiens protein ( Human Duchenne
muscle dystrophy (Dmd) gene for dystrophin exon 45. ).
Length = 58
Score = 31.1 bits (67), Expect = 3.6
Identities = 13/58 (22%), Positives = 27/58 (46%)
Frame = +1
Query: 253 EFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQR 426
E Q + +Q TG+ + ++ K D + L+ + + +W VC + DR++
Sbjct: 1 ELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKK 58
>X13048-1|CAA31454.1| 58|Homo sapiens protein ( Human Duchenne
muscular dystrophy gene exon 48 and flanks. ).
Length = 58
Score = 31.1 bits (67), Expect = 3.6
Identities = 13/58 (22%), Positives = 27/58 (46%)
Frame = +1
Query: 253 EFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTKWTTVCSKAVDRQR 426
E Q + +Q TG+ + ++ K D + L+ + + +W VC + DR++
Sbjct: 1 ELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKK 58
>DQ480334-1|ABF19573.1| 350|Homo sapiens catecholamine-regulated
protein 40 protein.
Length = 350
Score = 30.7 bits (66), Expect = 4.7
Identities = 24/96 (25%), Positives = 48/96 (50%)
Frame = +1
Query: 73 KSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIKQRLNKHR 252
K+AE+ D KE E +M + +++TE +++ + ++ +K+K+ ++K R
Sbjct: 230 KNAEKYAEEDRRKKERVEAVNMAEGI---IHDTETKMEGFKDQLPADECNKLKEEISKMR 286
Query: 253 EFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLK 360
E LA K D +TG++++ A + LK
Sbjct: 287 EL---LARKDSEKD--SETGENIRQAASSLQQASLK 317
>L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2649
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
>BC065536-1|AAH65536.1| 1143|Homo sapiens DST protein protein.
Length = 1143
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
>AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein.
Length = 2649
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
>AL096710-5|CAI22046.1| 3060|Homo sapiens dystonin protein.
Length = 3060
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
>AK128631-1|BAC87539.1| 544|Homo sapiens protein ( Homo sapiens
cDNA FLJ46790 fis, clone TRACH3029329. ).
Length = 544
Score = 30.3 bits (65), Expect = 6.2
Identities = 26/130 (20%), Positives = 57/130 (43%)
Frame = +1
Query: 28 NLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEAT 207
NL++ Q ++++V ++ RT L+ + +E+SD+ + W+ T L A
Sbjct: 150 NLMIPFQ-QYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLL------AN 202
Query: 208 VNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMKTK 387
D D ++ + Q AL + ++L L+D + + + L I ++ +
Sbjct: 203 PADYDSLRTLSHHASTVQMALEDSEQKHNLLHSIFTDLEDLSIIFETDELTQSIQELSNQ 262
Query: 388 WTTVCSKAVD 417
T + K ++
Sbjct: 263 VTALQQKIME 272
>AF400227-1|AAL62062.1| 3060|Homo sapiens bullous pemphigoid antigen
1 eB protein.
Length = 3060
Score = 30.3 bits (65), Expect = 6.2
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%)
Frame = +1
Query: 49 HRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLN-SEATVNDPDK 225
HR E +K +R + F N + WLNE EE+ + SE N
Sbjct: 352 HRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTN---- 407
Query: 226 IKQRLNKHREFQKALASKQPAYDLTMKTGKH-LKDKAPKGDENPLKTMITDMKTKWTTVC 402
I ++ + H E + L K+ + + L + P ++ M+T+W+ +
Sbjct: 408 IARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPA--RLTIEAYRAAMQTQWSWIL 465
Query: 403 SKAVDRQRKLEEALLYSGQFKDAMSA 480
++ ++E Y F DA A
Sbjct: 466 QLCQCVEQHIKENTAYFEFFNDAKEA 491
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 944 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 1002
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 1003 TQLNQQKMLVSEIEMKQSKMDECQK 1027
>U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated
protein 1A protein.
Length = 1604
Score = 29.9 bits (64), Expect = 8.2
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Frame = +1
Query: 40 SVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDP 219
S+Q + VSK A+R ++ G KEA+ + L L +TE++ + +SE P
Sbjct: 245 SLQATTKTAVSKLAKREEVVEEGAKEAR------SELAKELAKTEKKAKE-SSEKPPEKP 297
Query: 220 DKIKQRLNKHREFQKALASKQPAYDLTMKTG-KHLKDKAPKGDE 348
K ++ + E KA K + K G KHLK+K K +E
Sbjct: 298 AKPERVKTESSEALKAEKRKL----IKDKVGKKHLKEKISKLEE 337
>M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2095
Score = 29.9 bits (64), Expect = 8.2
Identities = 19/85 (22%), Positives = 35/85 (41%)
Frame = +1
Query: 52 RWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSEATVNDPDKIK 231
RW+ V + R R L+ K K + D ++ L +W+ + E ++ N +
Sbjct: 390 RWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENS-KTLA 448
Query: 232 QRLNKHREFQKALASKQPAYDLTMK 306
+LN+ + + KQ D K
Sbjct: 449 TQLNQQKMLVSEIEMKQSKMDECQK 473
>BC039121-1|AAH39121.1| 510|Homo sapiens SYNE1 protein protein.
Length = 510
Score = 29.9 bits (64), Expect = 8.2
Identities = 23/157 (14%), Positives = 70/157 (44%)
Frame = +1
Query: 22 IKNLLVSVQHRWERVVSKSAERTRALDHGFKEAKEFSDMWNNLMNWLNETEEQLDQLNSE 201
I+ + + + W+ S ++ AL++ + K+F + +WL++TE+ + + +S
Sbjct: 259 IQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHE-SSN 317
Query: 202 ATVNDPDKIKQRLNKHREFQKALASKQPAYDLTMKTGKHLKDKAPKGDENPLKTMITDMK 381
+ P K +++ K + + + +P + + + L + + + ++ +
Sbjct: 318 RLYDLPAKRREQ-QKLQSVLEEIHCYEPQLNRLKEKAQQLWE--GQAASKSFRHRVSQLS 374
Query: 382 TKWTTVCSKAVDRQRKLEEALLYSGQFKDAMSALLDW 492
+++ + + ++ +L+ + QF + L DW
Sbjct: 375 SQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDW 411
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.314 0.129 0.379
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 87,616,628
Number of Sequences: 237096
Number of extensions: 1738241
Number of successful extensions: 15586
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 13414
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15056
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.5 bits)
- SilkBase 1999-2023 -