Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--2249
(625 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D5595A Cluster: PREDICTED: similar to CG18214-PA... 292 4e-78
UniRef50_Q7KY09 Cluster: Trio; n=10; Diptera|Rep: Trio - Drosoph... 281 1e-74
UniRef50_O60229 Cluster: Kalirin; n=25; Eumetazoa|Rep: Kalirin -... 248 6e-65
UniRef50_UPI000065D244 Cluster: Triple functional domain protein... 246 3e-64
UniRef50_O75962 Cluster: Triple functional domain protein; n=71;... 246 3e-64
UniRef50_A7RXC9 Cluster: Predicted protein; n=1; Nematostella ve... 199 5e-50
UniRef50_Q4RFA4 Cluster: Chromosome 8 SCAF15119, whole genome sh... 120 1e-47
UniRef50_UPI0000F34917 Cluster: UPI0000F34917 related cluster; n... 145 9e-34
UniRef50_Q4S0P7 Cluster: Chromosome 2 SCAF14781, whole genome sh... 143 4e-33
UniRef50_O15068 Cluster: Guanine nucleotide exchange factor DBS;... 142 5e-33
UniRef50_Q4SUB9 Cluster: Chromosome 3 SCAF13974, whole genome sh... 118 5e-32
UniRef50_Q4RY59 Cluster: Chromosome 3 SCAF14978, whole genome sh... 132 7e-30
UniRef50_O61528 Cluster: Guanine nucleotide exchange factor UNC-... 130 3e-29
UniRef50_P10911 Cluster: Proto-oncogene DBL (Proto-oncogene MCF-... 130 3e-29
UniRef50_UPI000065F563 Cluster: Homolog of Brachydanio rerio "Qu... 125 1e-27
UniRef50_Q96PX9 Cluster: KIAA1909 protein; n=12; Euteleostomi|Re... 124 1e-27
UniRef50_UPI000058400D Cluster: PREDICTED: hypothetical protein;... 124 2e-27
UniRef50_Q4RP67 Cluster: Chromosome 1 SCAF15008, whole genome sh... 87 9e-27
UniRef50_UPI00015B606E Cluster: PREDICTED: similar to ENSANGP000... 120 2e-26
UniRef50_UPI0000F211CF Cluster: PREDICTED: similar to RAC/CDC42 ... 118 9e-26
UniRef50_Q1RLV0 Cluster: Zgc:136817; n=3; Danio rerio|Rep: Zgc:1... 118 1e-25
UniRef50_UPI0000DB73BC Cluster: PREDICTED: similar to Guanine nu... 118 2e-25
UniRef50_Q4SVF8 Cluster: Chromosome 7 SCAF13760, whole genome sh... 118 2e-25
UniRef50_Q7Z2K2 Cluster: Transforming gene product TGAT; n=2; Eu... 118 2e-25
UniRef50_Q9Y2A5 Cluster: Serine/threonine-protein kinase Duet; n... 117 2e-25
UniRef50_Q6DN89 Cluster: Quattro; n=2; Eumetazoa|Rep: Quattro - ... 117 3e-25
UniRef50_Q16L87 Cluster: Dbl; n=3; Fungi/Metazoa group|Rep: Dbl ... 116 5e-25
UniRef50_UPI0000D55959 Cluster: PREDICTED: similar to CG18214-PD... 115 8e-25
UniRef50_UPI00004D56CF Cluster: Puratrophin-1 (Pleckstrin homolo... 114 1e-24
UniRef50_UPI0000F1E6F8 Cluster: PREDICTED: hypothetical protein;... 114 2e-24
UniRef50_UPI0000F1E2DD Cluster: PREDICTED: similar to RAC/CDC42 ... 113 2e-24
UniRef50_UPI000065F2B5 Cluster: Huntingtin-associated protein-in... 113 3e-24
UniRef50_Q4RTS6 Cluster: Chromosome 2 SCAF14997, whole genome sh... 111 1e-23
UniRef50_A7SVF8 Cluster: Predicted protein; n=1; Nematostella ve... 111 2e-23
UniRef50_A0NEN5 Cluster: ENSANGP00000031634; n=2; Culicidae|Rep:... 111 2e-23
UniRef50_UPI0000F2B983 Cluster: PREDICTED: similar to FLJ00068 p... 110 2e-23
UniRef50_Q7K4E0 Cluster: LD43457p; n=2; Sophophora|Rep: LD43457p... 109 5e-23
UniRef50_UPI0000F21533 Cluster: PREDICTED: hypothetical protein;... 109 7e-23
UniRef50_UPI00015A5797 Cluster: UPI00015A5797 related cluster; n... 109 7e-23
UniRef50_UPI00015B51B1 Cluster: PREDICTED: similar to conserved ... 108 9e-23
UniRef50_Q86VW2 Cluster: RhoA/RAC/CDC42 exchange factor; n=52; T... 108 9e-23
UniRef50_Q7KU89 Cluster: CG33275-PA, isoform A; n=7; Diptera|Rep... 106 4e-22
UniRef50_UPI0000E80D31 Cluster: PREDICTED: hypothetical protein;... 75 4e-22
UniRef50_UPI00005A5680 Cluster: PREDICTED: similar to pleckstrin... 106 5e-22
UniRef50_UPI0001554F5B Cluster: PREDICTED: similar to FLJ00068 p... 104 2e-21
UniRef50_UPI0000519A5C Cluster: PREDICTED: similar to CG33275-PC... 103 5e-21
UniRef50_Q4S810 Cluster: Chromosome 9 SCAF14710, whole genome sh... 101 1e-20
UniRef50_Q17DQ5 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20
UniRef50_Q58EX7 Cluster: Puratrophin-1; n=18; Eutheria|Rep: Pura... 101 2e-20
UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB... 95 2e-18
UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP000... 92 9e-18
UniRef50_A7SFH2 Cluster: Predicted protein; n=1; Nematostella ve... 90 3e-17
UniRef50_Q86YR7 Cluster: Rho family guanine-nucleotide exchange ... 89 1e-16
UniRef50_UPI0000EB3077 Cluster: pleckstrin homology domain conta... 87 3e-16
UniRef50_A1L390 Cluster: Pleckstrin homology domain-containing f... 87 3e-16
UniRef50_Q4VAC9 Cluster: Pleckstrin homology domain-containing f... 87 4e-16
UniRef50_Q4SEW8 Cluster: Chromosome undetermined SCAF14611, whol... 85 2e-15
UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome s... 84 2e-15
UniRef50_Q9ULL1 Cluster: Pleckstrin homology domain-containing f... 84 3e-15
UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep: ... 83 5e-15
UniRef50_Q4RLN1 Cluster: Chromosome 10 SCAF15019, whole genome s... 81 2e-14
UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -... 81 2e-14
UniRef50_Q4S6V2 Cluster: Chromosome 14 SCAF14723, whole genome s... 81 2e-14
UniRef50_UPI0000F210AF Cluster: PREDICTED: hypothetical protein;... 79 6e-14
UniRef50_UPI00015A58C2 Cluster: Pleckstrin homology domain-conta... 79 6e-14
UniRef50_UPI000065FF36 Cluster: Homolog of Homo sapiens "pleckst... 77 3e-13
UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ... 75 1e-12
UniRef50_Q17LU2 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12
UniRef50_O02133 Cluster: Temporarily assigned gene name protein ... 73 6e-12
UniRef50_A1ZBA1 Cluster: CG30115-PD, isoform D; n=4; Sophophora|... 72 1e-11
UniRef50_Q4SB72 Cluster: Chromosome undetermined SCAF14677, whol... 70 4e-11
UniRef50_A0NBJ0 Cluster: ENSANGP00000029817; n=1; Anopheles gamb... 70 5e-11
UniRef50_Q9H7P9 Cluster: Pleckstrin homology domain-containing f... 70 5e-11
UniRef50_UPI0000DA3D65 Cluster: PREDICTED: similar to mcf.2 tran... 69 7e-11
UniRef50_Q4RXW9 Cluster: Chromosome 11 SCAF14979, whole genome s... 69 9e-11
UniRef50_UPI0000D55943 Cluster: PREDICTED: similar to Pleckstrin... 65 1e-09
UniRef50_Q7QGJ0 Cluster: ENSANGP00000019802; n=4; Culicidae|Rep:... 65 1e-09
UniRef50_UPI000065DEA3 Cluster: Homolog of Brachydanio rerio "Qu... 65 1e-09
UniRef50_UPI000051ACFC Cluster: PREDICTED: similar to Pleckstrin... 63 5e-09
UniRef50_Q96N96 Cluster: Spermatogenesis-associated protein 13; ... 62 1e-08
UniRef50_UPI00015B4CDD Cluster: PREDICTED: similar to pleckstrin... 62 1e-08
UniRef50_O96035 Cluster: PEM-2; n=1; Ciona savignyi|Rep: PEM-2 -... 61 2e-08
UniRef50_UPI000155FBE9 Cluster: PREDICTED: hypothetical protein;... 60 3e-08
UniRef50_UPI0000D575D3 Cluster: PREDICTED: similar to Rho guanin... 60 4e-08
UniRef50_Q4SQR9 Cluster: Chromosome undetermined SCAF14531, whol... 60 4e-08
UniRef50_Q5ZLR6 Cluster: Rho guanine nucleotide exchange factor ... 60 4e-08
UniRef50_Q17KZ4 Cluster: Putative uncharacterized protein; n=2; ... 60 6e-08
UniRef50_UPI0000F3273F Cluster: pleckstrin homology domain conta... 59 7e-08
UniRef50_P40995 Cluster: Rho guanine nucleotide exchange factor ... 59 7e-08
UniRef50_Q4SFB4 Cluster: Chromosome 6 SCAF14605, whole genome sh... 59 1e-07
UniRef50_Q4SIP5 Cluster: Chromosome 21 SCAF14577, whole genome s... 58 1e-07
UniRef50_A4R6Z2 Cluster: Putative uncharacterized protein; n=2; ... 58 1e-07
UniRef50_UPI000069EC71 Cluster: CDNA FLJ43173 fis, clone FCBBF30... 56 5e-07
UniRef50_Q9XXM9 Cluster: Putative uncharacterized protein uig-1;... 56 7e-07
UniRef50_Q4PBU1 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q4RY71 Cluster: Chromosome 3 SCAF14978, whole genome sh... 55 2e-06
UniRef50_UPI0000F21464 Cluster: PREDICTED: hypothetical protein;... 54 3e-06
UniRef50_UPI0000E463E9 Cluster: PREDICTED: similar to Cdc42 guan... 54 3e-06
UniRef50_UPI0000DA28FB Cluster: PREDICTED: similar to DEP domain... 54 3e-06
UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob... 54 4e-06
UniRef50_Q9NR80 Cluster: Rho guanine nucleotide exchange factor ... 53 5e-06
UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor ... 53 6e-06
UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome sh... 52 8e-06
UniRef50_A7RTF1 Cluster: Predicted protein; n=8; Eumetazoa|Rep: ... 52 8e-06
UniRef50_Q70Z35 Cluster: DEP domain-containing protein 2 (Phosph... 52 8e-06
UniRef50_Q7S4Y3 Cluster: Putative uncharacterized protein NCU060... 52 1e-05
UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep... 52 1e-05
UniRef50_Q4RP06 Cluster: Chromosome 10 SCAF15009, whole genome s... 51 2e-05
UniRef50_UPI000049A257 Cluster: Rho guanine nucleotide exchange ... 51 3e-05
UniRef50_Q17KZ0 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_A0FEW6 Cluster: Cdc24; n=2; Filobasidiella neoformans|R... 51 3e-05
UniRef50_Q960B3 Cluster: SD09786p; n=4; Sophophora|Rep: SD09786p... 50 3e-05
UniRef50_A7RK39 Cluster: Predicted protein; n=1; Nematostella ve... 50 3e-05
UniRef50_Q6CBW7 Cluster: Yarrowia lipolytica chromosome C of str... 50 3e-05
UniRef50_Q14155 Cluster: Rho guanine nucleotide exchange factor ... 50 3e-05
UniRef50_Q13009 Cluster: T-lymphoma invasion and metastasis-indu... 50 5e-05
UniRef50_UPI0001555B97 Cluster: PREDICTED: similar to FLJ00056 p... 50 6e-05
UniRef50_Q7Z628 Cluster: Neuroepithelial cell-transforming gene ... 50 6e-05
UniRef50_UPI0000F1DCF3 Cluster: PREDICTED: hypothetical protein;... 49 8e-05
UniRef50_UPI0000519B3F Cluster: PREDICTED: similar to FYVE, RhoG... 49 8e-05
UniRef50_UPI000049A4D9 Cluster: Rho guanine nucleotide exchange ... 49 8e-05
UniRef50_Q5RH33 Cluster: Novel protein similar to human and mous... 49 8e-05
UniRef50_Q16JM6 Cluster: Rho guanine exchange factor; n=2; Culic... 49 8e-05
UniRef50_Q0UQ03 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05
UniRef50_Q8TCU6 Cluster: Phosphatidylinositol 3,4,5-trisphosphat... 49 8e-05
UniRef50_UPI0000F1FC93 Cluster: PREDICTED: hypothetical protein;... 49 1e-04
UniRef50_UPI0000E477CD Cluster: PREDICTED: similar to GH10341p; ... 49 1e-04
UniRef50_UPI0000E47B1C Cluster: PREDICTED: similar to TUBA; n=2;... 48 1e-04
UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ... 48 1e-04
UniRef50_Q54GP2 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_UPI000049A2CA Cluster: Rho guanine nucleotide exchange ... 48 2e-04
UniRef50_Q553D3 Cluster: Pleckstrin homology (PH) domain-contain... 48 2e-04
UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:... 48 2e-04
UniRef50_P91621 Cluster: Protein still life, isoform SIF type 1;... 48 2e-04
UniRef50_UPI0000E4A769 Cluster: PREDICTED: similar to vav 2 onco... 48 2e-04
UniRef50_Q1RMS9 Cluster: FGD6 protein; n=11; Amniota|Rep: FGD6 p... 48 2e-04
UniRef50_Q17DC1 Cluster: Still life, putative; n=5; Endopterygot... 48 2e-04
UniRef50_UPI000049976C Cluster: hypothetical protein 115.t00004;... 47 3e-04
UniRef50_Q6ZV73 Cluster: FYVE, RhoGEF and PH domain-containing p... 47 3e-04
UniRef50_UPI00015B50AC Cluster: PREDICTED: similar to FYVE, RhoG... 47 4e-04
UniRef50_UPI0000498C66 Cluster: actin-binding protein; n=1; Enta... 47 4e-04
UniRef50_Q4S0P4 Cluster: Chromosome 2 SCAF14781, whole genome sh... 47 4e-04
UniRef50_Q7Z6J4 Cluster: FYVE, RhoGEF and PH domain-containing p... 47 4e-04
UniRef50_Q54DW7 Cluster: Pleckstrin homology (PH) domain-contain... 46 6e-04
UniRef50_Q1ZXN6 Cluster: Pleckstrin homology (PH) domain-contain... 46 6e-04
UniRef50_Q96M96 Cluster: FYVE, RhoGEF and PH domain-containing p... 46 6e-04
UniRef50_Q6WKY8 Cluster: Guanine nucleotide exchange factor; n=2... 46 7e-04
UniRef50_Q9VS45 Cluster: CG8606-PA, isoform A; n=4; Sophophora|R... 46 0.001
UniRef50_Q9GTU9 Cluster: Rho guanine nucleotide exchange factor ... 46 0.001
UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.001
UniRef50_Q5JSP0 Cluster: FYVE, RhoGEF and PH domain-containing p... 46 0.001
UniRef50_Q4RFR9 Cluster: Chromosome 16 SCAF15113, whole genome s... 45 0.001
UniRef50_A6S9L4 Cluster: Putative uncharacterized protein; n=2; ... 45 0.001
UniRef50_UPI0001555442 Cluster: PREDICTED: similar to FYVE, RhoG... 45 0.002
UniRef50_Q4RJT9 Cluster: Chromosome 9 SCAF15033, whole genome sh... 45 0.002
UniRef50_Q8TER5 Cluster: FLJ00128 protein; n=30; Tetrapoda|Rep: ... 45 0.002
UniRef50_Q86HN1 Cluster: Similar to PH (Pleckstrin homology) dom... 44 0.002
UniRef50_A0CSX7 Cluster: Chromosome undetermined scaffold_26, wh... 44 0.002
UniRef50_P98174 Cluster: FYVE, RhoGEF and PH domain-containing p... 44 0.002
UniRef50_UPI0000DA2C9A Cluster: PREDICTED: similar to FYVE, RhoG... 44 0.003
UniRef50_UPI00004992B4 Cluster: Rho guanine nucleotide exchange ... 44 0.003
UniRef50_Q4TC49 Cluster: Chromosome undetermined SCAF7053, whole... 44 0.003
UniRef50_Q4S5A8 Cluster: Chromosome 19 SCAF14731, whole genome s... 44 0.003
UniRef50_Q54B37 Cluster: Pleckstrin homology (PH) domain-contain... 44 0.003
UniRef50_Q9NR81 Cluster: Rho guanine nucleotide exchange factor ... 44 0.003
UniRef50_Q504F6 Cluster: Zgc:109904; n=5; Euteleostomi|Rep: Zgc:... 44 0.004
UniRef50_Q1ZXH8 Cluster: Pleckstrin homology (PH) domain-contain... 44 0.004
UniRef50_Q9UKW0 Cluster: T-cell lymphoma invasion and metastasis... 44 0.004
UniRef50_Q9HF59 Cluster: Cdc24; n=2; Saccharomycetaceae|Rep: Cdc... 44 0.004
UniRef50_Q1E796 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q54DE0 Cluster: Calmodulin-binding protein; n=2; Dictyo... 43 0.005
UniRef50_A2F0J5 Cluster: Kelch motif family protein; n=1; Tricho... 43 0.005
UniRef50_A6QW04 Cluster: Putative uncharacterized protein; n=1; ... 43 0.005
UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Interse... 43 0.007
UniRef50_Q4SFX7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 43 0.007
UniRef50_Q54MM3 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_Q54BY9 Cluster: Pleckstrin homology (PH) domain-contain... 43 0.007
UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersecti... 42 0.009
UniRef50_UPI0000499324 Cluster: Rho guanine nucleotide exchange ... 42 0.009
UniRef50_UPI00006A1ACD Cluster: FYVE, RhoGEF and PH domain-conta... 42 0.009
UniRef50_Q6Q427 Cluster: Guanine nucleotide exchange factor; n=4... 42 0.009
UniRef50_A7SEJ8 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.009
UniRef50_UPI0000E46C3C Cluster: PREDICTED: hypothetical protein;... 42 0.012
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.012
UniRef50_A1ZAQ4 Cluster: CG15611-PA, isoform A; n=5; Sophophora|... 42 0.012
UniRef50_UPI0000D577DA Cluster: PREDICTED: similar to CG7893-PA,... 42 0.016
UniRef50_UPI00004983B6 Cluster: cell division control protein CD... 42 0.016
UniRef50_Q4SEL7 Cluster: Chromosome 10 SCAF14616, whole genome s... 42 0.016
UniRef50_A7SS01 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.021
UniRef50_A2QIY3 Cluster: Complex: the S. pombe proteins scd1; n=... 41 0.021
UniRef50_UPI0000D55C29 Cluster: PREDICTED: similar to CG8606-PA,... 41 0.028
UniRef50_Q4SU01 Cluster: Chromosome 7 SCAF14053, whole genome sh... 41 0.028
UniRef50_A7SKW6 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.028
UniRef50_A0C114 Cluster: Chromosome undetermined scaffold_140, w... 41 0.028
UniRef50_O94887 Cluster: FERM, RhoGEF and pleckstrin domain-cont... 41 0.028
UniRef50_A5DJC8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.037
UniRef50_UPI00005887C8 Cluster: PREDICTED: similar to Rho guanin... 40 0.048
UniRef50_Q4SCD4 Cluster: Chromosome undetermined SCAF14659, whol... 40 0.048
UniRef50_Q54VX2 Cluster: Pleckstrin homology (PH) domain-contain... 40 0.048
UniRef50_Q54J14 Cluster: Putative uncharacterized protein; n=1; ... 40 0.048
UniRef50_A7S9N2 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.048
UniRef50_A7S9L2 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.048
UniRef50_A5E275 Cluster: Putative uncharacterized protein; n=1; ... 40 0.048
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 40 0.048
UniRef50_UPI0000DB6CBB Cluster: PREDICTED: similar to dynamin bi... 40 0.064
UniRef50_UPI0000499FFA Cluster: Rho guanine nucleotide exchange ... 40 0.064
UniRef50_Q54UJ2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.064
UniRef50_A0E1W1 Cluster: Chromosome undetermined scaffold_74, wh... 40 0.064
UniRef50_Q9UTR5 Cluster: Rho1 guanine nucleotide exchange factor... 40 0.064
UniRef50_A0D0E6 Cluster: Chromosome undetermined scaffold_33, wh... 39 0.085
UniRef50_Q96PE2 Cluster: Rho guanine nucleotide exchange factor ... 39 0.085
UniRef50_UPI000049A230 Cluster: hypothetical protein 13.t00058; ... 39 0.11
UniRef50_UPI000065F5D5 Cluster: Rho guanine nucleotide exchange ... 39 0.11
UniRef50_Q4SSS2 Cluster: Chromosome undetermined SCAF14347, whol... 39 0.11
UniRef50_Q54J11 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11
UniRef50_Q18372 Cluster: Putative uncharacterized protein exc-5;... 39 0.11
UniRef50_A0CZ33 Cluster: Chromosome undetermined scaffold_31, wh... 39 0.11
UniRef50_Q5KI94 Cluster: GrfA protein, putative; n=2; Filobasidi... 39 0.11
UniRef50_A1DEX6 Cluster: Rho guanyl nucleotide exchange factor (... 39 0.11
UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep: ... 39 0.11
UniRef50_UPI0000E49080 Cluster: PREDICTED: hypothetical protein;... 38 0.15
UniRef50_A0MTB7 Cluster: Intersectin 1-like protien; n=1; Trichi... 38 0.15
UniRef50_Q9Y7U6 Cluster: Rho1 guanine nucleotide exchange factor... 38 0.15
UniRef50_UPI0000E48DF2 Cluster: PREDICTED: similar to Bcr protei... 38 0.20
UniRef50_Q6FIT2 Cluster: Candida glabrata strain CBS138 chromoso... 38 0.20
UniRef50_A2F021 Cluster: RhoGEF domain containing protein; n=1; ... 38 0.26
UniRef50_Q6CDY6 Cluster: Similar to tr|Q9Y7U6 Schizosaccharomyce... 38 0.26
UniRef50_A3LN99 Cluster: Gdp-GTP Exchange Protein (GEP) for the ... 38 0.26
UniRef50_P52746 Cluster: Zinc finger protein 142; n=20; Eutheria... 38 0.26
UniRef50_Q4SPQ5 Cluster: Chromosome 16 SCAF14537, whole genome s... 37 0.34
UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG3351... 37 0.34
UniRef50_Q4P5Y6 Cluster: Putative uncharacterized protein; n=1; ... 37 0.34
UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep: Int... 37 0.34
UniRef50_UPI0000DB6CE7 Cluster: PREDICTED: similar to Guanine nu... 37 0.45
UniRef50_UPI0000499563 Cluster: 158792 GrfA protein; n=1; Entamo... 37 0.45
UniRef50_UPI0000498C1F Cluster: Rho guanine nucleotide exchange ... 37 0.45
UniRef50_Q4RG84 Cluster: Chromosome 2 SCAF15106, whole genome sh... 37 0.45
UniRef50_Q54SR5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.45
UniRef50_A7SRN5 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.45
UniRef50_Q5VV41 Cluster: Rho guanine nucleotide exchange factor ... 37 0.45
UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB... 36 0.60
UniRef50_UPI00006CB721 Cluster: RhoGEF domain containing protein... 36 0.60
UniRef50_Q54YZ6 Cluster: RhoGEF domain-containing protein; n=1; ... 36 0.60
UniRef50_Q54PK2 Cluster: Putative uncharacterized protein; n=1; ... 36 0.60
UniRef50_Q54C56 Cluster: Putative uncharacterized protein; n=1; ... 36 0.60
UniRef50_Q21653 Cluster: Uncharacterized protein R02F2.2; n=1; C... 36 0.60
UniRef50_UPI0000F1F644 Cluster: PREDICTED: hypothetical protein;... 36 0.79
UniRef50_UPI000051A1F0 Cluster: PREDICTED: similar to CG3799-PA,... 36 0.79
UniRef50_UPI000049944B Cluster: Rho guanine nucleotide exchange ... 36 0.79
UniRef50_A7CXR3 Cluster: ABC transporter related; n=1; Opitutace... 36 0.79
UniRef50_A0CQC8 Cluster: Chromosome undetermined scaffold_24, wh... 36 0.79
UniRef50_Q875H9 Cluster: Guanine nucleotide exchange factor Cdc2... 36 0.79
UniRef50_Q02425 Cluster: Putative transcriptional regulator mtlR... 36 0.79
UniRef50_Q4T952 Cluster: Chromosome undetermined SCAF7638, whole... 36 1.0
UniRef50_Q4SKH1 Cluster: Chromosome 13 SCAF14566, whole genome s... 36 1.0
UniRef50_Q9A3T3 Cluster: Efflux system protein, putative; n=2; C... 36 1.0
UniRef50_A1ZN71 Cluster: Naringenin-chalcone synthase; n=1; Micr... 36 1.0
UniRef50_A7RJS1 Cluster: Predicted protein; n=2; Nematostella ve... 36 1.0
UniRef50_A0E7D3 Cluster: Chromosome undetermined scaffold_81, wh... 36 1.0
UniRef50_A0D4V7 Cluster: Chromosome undetermined scaffold_38, wh... 36 1.0
UniRef50_Q6BKC6 Cluster: Similarities with CA4497|IPF4064 Candid... 36 1.0
UniRef50_Q1DHH2 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_P11433 Cluster: Cell division control protein 24; n=3; ... 36 1.0
UniRef50_UPI00006CC97C Cluster: RhoGEF domain containing protein... 35 1.4
UniRef50_UPI0000499B27 Cluster: Rho guanine nucleotide exchange ... 35 1.4
UniRef50_UPI0000498811 Cluster: protein with RhoGEF and ArfGAP d... 35 1.4
UniRef50_UPI000023D96C Cluster: hypothetical protein FG08568.1; ... 35 1.4
UniRef50_Q4RW86 Cluster: Chromosome 9 SCAF14991, whole genome sh... 35 1.4
UniRef50_A7NY29 Cluster: Chromosome chr6 scaffold_3, whole genom... 35 1.4
UniRef50_Q4Q834 Cluster: Putative uncharacterized protein; n=3; ... 35 1.4
UniRef50_Q21430 Cluster: Putative uncharacterized protein pix-1;... 35 1.4
UniRef50_Q17J92 Cluster: Putative uncharacterized protein; n=1; ... 35 1.4
UniRef50_Q2GWA2 Cluster: Putative uncharacterized protein; n=2; ... 35 1.4
UniRef50_UPI00015B5708 Cluster: PREDICTED: similar to ENSANGP000... 35 1.8
UniRef50_UPI00015B49F8 Cluster: PREDICTED: similar to conserved ... 35 1.8
UniRef50_UPI0000F2028B Cluster: PREDICTED: hypothetical protein;... 35 1.8
UniRef50_UPI0000DB6C3F Cluster: PREDICTED: similar to CG7397-PA;... 35 1.8
UniRef50_UPI0000498513 Cluster: Rho guanine nucleotide exchange ... 35 1.8
UniRef50_Q4S825 Cluster: Chromosome 9 SCAF14710, whole genome sh... 35 1.8
UniRef50_Q1LYR1 Cluster: Novel protein; n=5; Danio rerio|Rep: No... 35 1.8
UniRef50_Q3W6S5 Cluster: Transcriptional regulatory protein, C t... 35 1.8
UniRef50_Q9NVK9 Cluster: CDNA FLJ10665 fis, clone NT2RP2006200; ... 35 1.8
UniRef50_UPI0000DB70D0 Cluster: PREDICTED: similar to pebble CG8... 34 2.4
UniRef50_UPI000049A5B0 Cluster: Rho guanine nucleotide exchange ... 34 2.4
UniRef50_UPI0000498DC6 Cluster: protein with RhoGEF and ArfGAP d... 34 2.4
UniRef50_UPI0000498657 Cluster: Rho guanine nucleotide exchange ... 34 2.4
UniRef50_UPI0000498409 Cluster: Rho guanine nucleotide exchange ... 34 2.4
UniRef50_UPI000069FF5A Cluster: Dynamin-binding protein (Scaffol... 34 2.4
UniRef50_Q55G61 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4
UniRef50_Q290B3 Cluster: GA15699-PA; n=1; Drosophila pseudoobscu... 34 2.4
UniRef50_Q1ZYL3 Cluster: Rho guanine nucleotide exchange factor ... 34 2.4
UniRef50_Q9Y7U5 Cluster: Rho1 guanine nucleotide exchange factor... 34 2.4
UniRef50_UPI0000E46C03 Cluster: PREDICTED: similar to Intersecti... 34 3.2
UniRef50_UPI000049A2CD Cluster: hypothetical protein 130.t00020;... 34 3.2
UniRef50_UPI0000498ACC Cluster: Rho guanine nucleotide exchange ... 34 3.2
UniRef50_Q6GLN1 Cluster: LOC443708 protein; n=2; Xenopus|Rep: LO... 34 3.2
UniRef50_Q4H389 Cluster: Transcription factor protein; n=1; Cion... 34 3.2
UniRef50_A2FCU5 Cluster: Kelch motif family protein; n=1; Tricho... 34 3.2
UniRef50_A6RIQ1 Cluster: Putative uncharacterized protein; n=2; ... 34 3.2
UniRef50_UPI0000E49D6D Cluster: PREDICTED: similar to Ect2 prote... 33 4.2
UniRef50_UPI0000DB72CE Cluster: PREDICTED: similar to CG7323-PA;... 33 4.2
UniRef50_UPI000049943D Cluster: Rho guanine nucleotide exchange ... 33 4.2
UniRef50_UPI00015A61A4 Cluster: UPI00015A61A4 related cluster; n... 33 4.2
UniRef50_Q54SG9 Cluster: RhoGEF domain-containing protein; n=2; ... 33 4.2
UniRef50_Q29EA3 Cluster: GA16778-PA; n=3; Diptera|Rep: GA16778-P... 33 4.2
UniRef50_Q1RPY9 Cluster: Zinc finger protein; n=1; Ciona intesti... 33 4.2
UniRef50_A7RG07 Cluster: Predicted protein; n=1; Nematostella ve... 33 4.2
UniRef50_A0DT23 Cluster: Chromosome undetermined scaffold_62, wh... 33 4.2
UniRef50_Q11100 Cluster: Putative protein tag-52; n=2; Caenorhab... 33 4.2
UniRef50_UPI00015B4785 Cluster: PREDICTED: similar to ENSANGP000... 33 5.6
UniRef50_UPI00015B40BC Cluster: PREDICTED: similar to GA20259-PA... 33 5.6
UniRef50_UPI0000E8080B Cluster: PREDICTED: similar to TUBA; n=3;... 33 5.6
UniRef50_UPI0000E46F96 Cluster: PREDICTED: hypothetical protein;... 33 5.6
UniRef50_UPI0000E4620F Cluster: PREDICTED: hypothetical protein;... 33 5.6
UniRef50_UPI0000499880 Cluster: conserved hypothetical protein; ... 33 5.6
UniRef50_UPI0000498AB5 Cluster: hypothetical protein 22.t00029; ... 33 5.6
UniRef50_UPI0000660B3F Cluster: Rho guanine nucleotide exchange ... 33 5.6
UniRef50_UPI0000ECB580 Cluster: UPI0000ECB580 related cluster; n... 33 5.6
UniRef50_Q550V3 Cluster: Pleckstrin homology (PH) domain-contain... 33 5.6
UniRef50_Q54YP1 Cluster: Pleckstrin homology (PH) domain-contain... 33 5.6
UniRef50_Q4DFS4 Cluster: Putative uncharacterized protein; n=3; ... 33 5.6
UniRef50_UPI0000DA1F1A Cluster: PREDICTED: hypothetical protein;... 33 7.3
UniRef50_UPI0000499A44 Cluster: Rho guanine nucleotide exchange ... 33 7.3
UniRef50_UPI000049978D Cluster: Rho guanine nucleotide exchange ... 33 7.3
UniRef50_Q7ZZ90 Cluster: Novel protein similar to human MCF.2 ce... 33 7.3
UniRef50_Q6PEG8 Cluster: Serine/arginine repetitive matrix 1; n=... 33 7.3
UniRef50_Q965J0 Cluster: Temporarily assigned gene name protein ... 33 7.3
UniRef50_UPI00015B633C Cluster: PREDICTED: similar to dicer-1; n... 32 9.7
UniRef50_UPI00015B5EE5 Cluster: PREDICTED: similar to ENSANGP000... 32 9.7
UniRef50_UPI0001554ED1 Cluster: PREDICTED: similar to type XVIII... 32 9.7
UniRef50_Q4UKV4 Cluster: Guanosine polyphosphate pyrophosphohydr... 32 9.7
UniRef50_Q3JY69 Cluster: Putative uncharacterized protein; n=2; ... 32 9.7
UniRef50_Q9VEF9 Cluster: CG7397-PA; n=5; Diptera|Rep: CG7397-PA ... 32 9.7
UniRef50_Q7QDX8 Cluster: ENSANGP00000013669; n=2; Culicidae|Rep:... 32 9.7
UniRef50_Q55G27 Cluster: RhoGEF domain-containing protein; n=1; ... 32 9.7
UniRef50_Q1ZX99 Cluster: RhoGEF domain-containing protein; n=1; ... 32 9.7
UniRef50_Q17AI6 Cluster: Guanine nucleotide exchange factor; n=3... 32 9.7
UniRef50_A2EUZ9 Cluster: Kelch motif family protein; n=1; Tricho... 32 9.7
UniRef50_A0BKK3 Cluster: Chromosome undetermined scaffold_112, w... 32 9.7
UniRef50_Q5KIY2 Cluster: Putative uncharacterized protein; n=1; ... 32 9.7
UniRef50_Q5KH07 Cluster: Putative uncharacterized protein; n=2; ... 32 9.7
UniRef50_Q4PGM7 Cluster: Putative uncharacterized protein; n=1; ... 32 9.7
UniRef50_Q2HHQ1 Cluster: Putative uncharacterized protein; n=4; ... 32 9.7
UniRef50_P25042 Cluster: Repressor ROX1; n=2; Saccharomyces cere... 32 9.7
>UniRef50_UPI0000D5595A Cluster: PREDICTED: similar to CG18214-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG18214-PA, isoform A - Tribolium castaneum
Length = 1611
Score = 292 bits (717), Expect = 4e-78
Identities = 130/192 (67%), Positives = 158/192 (82%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN 190
P + GK+++IFGNIEEI+ FH +FL+EL+KYETMPEDVGHCFVTWA++FD+YV YC+N
Sbjct: 1278 PAAIHGKDEIIFGNIEEIYNFHNSIFLKELEKYETMPEDVGHCFVTWAQKFDIYVHYCKN 1337
Query: 191 KPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
KP+SN+ +VQH G YFE +Q+K K+EHP+AAYLIKPVQRITKYQLLLKDLQ+CC EGQGE
Sbjct: 1338 KPESNSLLVQHGGGYFEELQKKHKVEHPIAAYLIKPVQRITKYQLLLKDLQSCCNEGQGE 1397
Query: 371 IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTREES 550
IKDGLEVML+VPKKANDAMHLSL+EGCDV + LGEVVLQ S P +KG
Sbjct: 1398 IKDGLEVMLNVPKKANDAMHLSLVEGCDVSANKLGEVVLQDAFSVWDPKQLIRKGRERHI 1457
Query: 551 LLFDLHLAFWRK 586
LF+L+L F ++
Sbjct: 1458 FLFELYLLFTKE 1469
>UniRef50_Q7KY09 Cluster: Trio; n=10; Diptera|Rep: Trio - Drosophila
melanogaster (Fruit fly)
Length = 2263
Score = 281 bits (688), Expect = 1e-74
Identities = 128/191 (67%), Positives = 150/191 (78%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYC 184
SVP L G+ED+IFGNI+EIH FH+++FLREL+KYETMPEDVGHCFVTWA +FDMYV YC
Sbjct: 1318 SVPSALIGQEDVIFGNIKEIHHFHQKIFLRELEKYETMPEDVGHCFVTWASKFDMYVHYC 1377
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
+NKP SN +VQH G +FE +QR+ +++HPL AYLIKPVQRITKYQLLLKDL +CC E
Sbjct: 1378 KNKPTSNNLLVQHGGSFFEELQRRLEVDHPLPAYLIKPVQRITKYQLLLKDLLSCCEESH 1437
Query: 365 GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTRE 544
GEIK+GLEVML+VPKKANDAMHLSLLE CDV D LGEVVLQ +KG
Sbjct: 1438 GEIKEGLEVMLNVPKKANDAMHLSLLENCDVSVDKLGEVVLQDAFQAWDTKQIIRKGRER 1497
Query: 545 ESLLFDLHLAF 577
LF+L+L F
Sbjct: 1498 RVFLFELYLLF 1508
Score = 93.1 bits (221), Expect = 5e-18
Identities = 66/202 (32%), Positives = 104/202 (51%), Gaps = 10/202 (4%)
Frame = +2
Query: 2 ASVPLPLQ---GKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMY 172
+ +P+P GK L+F NI++I+ +H FLR L + P D+G A +F +Y
Sbjct: 1976 SDIPMPEDLKGGKMKLVFNNIKDIYEWHRDFFLRALRNCQKSPADLGPLIKRSATKFALY 2035
Query: 173 VSYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACC 352
+YC NKP S V H YF+ +++K L+ +IKPVQRITKY+LL+K++
Sbjct: 2036 YTYCSNKPLSEYIVSAHY-QYFDSIRQKLGHRLDLSNLIIKPVQRITKYELLIKEI-IKA 2093
Query: 353 AEGQG------EIKDGLEVMLSVPKKANDAM-HLSLLEGCDVPTDSLGEVVLQGLLSRVG 511
EG G +++ + M V K ND M L L+ D + G +++QG ++ V
Sbjct: 2094 TEGAGLYKEVPMLQEAYQQMKVVVKTVNDMMVVLRSLQDFDGEITAQGSLLMQGPMNCVV 2153
Query: 512 PSSDHQKGTREESLLFDLHLAF 577
++ QK + LF + F
Sbjct: 2154 DAA--QKHRELQVFLFQQIIIF 2173
Score = 41.1 bits (92), Expect = 0.021
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +3
Query: 489 KDSFHVWDLRQIIKKGRERRVFFSTCIWLFGE 584
+D+F WD +QII+KGRERRVF LF +
Sbjct: 1479 QDAFQAWDTKQIIRKGRERRVFLFELYLLFAK 1510
>UniRef50_O60229 Cluster: Kalirin; n=25; Eumetazoa|Rep: Kalirin - Homo
sapiens (Human)
Length = 1663
Score = 248 bits (608), Expect = 6e-65
Identities = 110/190 (57%), Positives = 144/190 (75%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P + KE +IFGNI+EI+ FH +FL+EL+KYE +PEDVGHCFVTWA +F MYV+YC+
Sbjct: 1318 IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCK 1377
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKPDSN +++HAG +F+ +Q++ L + +++YLIKPVQRITKYQLLLK+L CC EG+G
Sbjct: 1378 NKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKG 1437
Query: 368 EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTREE 547
E+KDGLEVMLSVPKKANDAMH+S+LEG D D GE++LQ P S +KG
Sbjct: 1438 ELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERH 1497
Query: 548 SLLFDLHLAF 577
LF++ L F
Sbjct: 1498 LFLFEISLVF 1507
>UniRef50_UPI000065D244 Cluster: Triple functional domain protein (EC
2.7.11.1) (PTPRF-interacting protein).; n=1; Takifugu
rubripes|Rep: Triple functional domain protein (EC
2.7.11.1) (PTPRF-interacting protein). - Takifugu
rubripes
Length = 3108
Score = 246 bits (602), Expect = 3e-64
Identities = 107/190 (56%), Positives = 146/190 (76%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P + KE +IFGN+++++ FH +FL+EL+KYE +PEDVGHCFVTWA +F MYV+YC+
Sbjct: 1387 IPPGVINKEHIIFGNMQDLYEFHHNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVNYCK 1446
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKPDS +++HAG+YF+ +Q++ +L + +++YLIKPVQRITKYQLLLK+L CC EG+G
Sbjct: 1447 NKPDSTQLILEHAGNYFDEIQQRHRLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKG 1506
Query: 368 EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTREE 547
EIKDGLEVMLSVPK+ANDAMHLS+LEG D +S GE++LQ P + +KG
Sbjct: 1507 EIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERH 1566
Query: 548 SLLFDLHLAF 577
LF++ L F
Sbjct: 1567 LFLFEMSLIF 1576
Score = 122 bits (293), Expect = 9e-27
Identities = 70/194 (36%), Positives = 111/194 (57%), Gaps = 4/194 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P ++GK+ +FGNI +I+ +H +FL EL+K + +G F+ R+ +MYV YC+
Sbjct: 2036 IPDDMKGKDKTVFGNINQIYDWHRDIFLGELEKCLEDSDQLGPLFLKHERKLNMYVVYCQ 2095
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEG- 361
NKP S V ++ YFE ++++ + + ++ LIKPVQRI KYQLLLKD L+ G
Sbjct: 2096 NKPKSEHIVSEYIDTYFEDMRQQLRHKLQISDLLIKPVQRIMKYQLLLKDFLKHSKKAGL 2155
Query: 362 -QGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGT 538
E++ +EVM VPK+ ND M++ L+G D + G ++LQ P H
Sbjct: 2156 ESVELEKAVEVMCIVPKRCNDMMNVGRLQGFDGKIVAQGRLLLQDTFMVSDPEGGHLGRM 2215
Query: 539 REESL-LFDLHLAF 577
+E + LF+ + F
Sbjct: 2216 KERRVFLFEQLVIF 2229
Score = 33.9 bits (74), Expect = 3.2
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +3
Query: 489 KDSFHVWDLRQIIKKGRERRVFFSTCIWLFGE 584
++SF VWD + +I+KGRER +F +F +
Sbjct: 1547 QESFQVWDPKTLIRKGRERHLFLFEMSLIFSK 1578
>UniRef50_O75962 Cluster: Triple functional domain protein; n=71;
Eumetazoa|Rep: Triple functional domain protein - Homo
sapiens (Human)
Length = 3038
Score = 246 bits (602), Expect = 3e-64
Identities = 109/190 (57%), Positives = 144/190 (75%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P + KE +IFGN++EI+ FH +FL+EL+KYE +PEDVGHCFVTWA +F MYV+YC+
Sbjct: 1270 IPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCK 1329
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKPDS +++HAG YF+ +Q++ L + +++YLIKPVQRITKYQLLLK+L CC EG+G
Sbjct: 1330 NKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKG 1389
Query: 368 EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTREE 547
EIKDGLEVMLSVPK+ANDAMHLS+LEG D +S GE++LQ P + +KG
Sbjct: 1390 EIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERH 1449
Query: 548 SLLFDLHLAF 577
LF++ L F
Sbjct: 1450 LFLFEMSLVF 1459
Score = 121 bits (292), Expect = 1e-26
Identities = 64/164 (39%), Positives = 97/164 (59%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H FL EL+K PE +G FV R MY++YC+
Sbjct: 1945 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQ 2004
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ- 364
NKP S V ++ +FE ++++ L LIKPVQRI KYQLLLKD +
Sbjct: 2005 NKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL 2064
Query: 365 --GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
E++ +EVM VP++ ND M++ L+G D + G+++LQ
Sbjct: 2065 DTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQ 2108
>UniRef50_A7RXC9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1529
Score = 199 bits (485), Expect = 5e-50
Identities = 92/191 (48%), Positives = 127/191 (66%), Gaps = 1/191 (0%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF-DMYVSYC 184
VP L GKE +IFGNI++I++FH FL+E++KYET PEDVG F+ W F YVSYC
Sbjct: 1265 VPAGLVGKESIIFGNIQDIYKFHSNTFLQEMEKYETHPEDVGEAFIEWGETFVRFYVSYC 1324
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
+NKP SN+ +++H G++F +Q ++AYLIKPVQRITKYQLLLKDL CC +
Sbjct: 1325 KNKPFSNSLLIEHGGNFFSDLQASYGHGLSISAYLIKPVQRITKYQLLLKDLLTCCEGSE 1384
Query: 365 GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTRE 544
++ GL+VMLSVP++ANDAM++++L G + D LG ++LQ + P +KG
Sbjct: 1385 NSLQAGLDVMLSVPRRANDAMYVNMLHGLEENLDHLGRIILQDAFTVFDPKLLRRKGKDR 1444
Query: 545 ESLLFDLHLAF 577
LF+ L F
Sbjct: 1445 HVFLFEQALVF 1455
>UniRef50_Q4RFA4 Cluster: Chromosome 8 SCAF15119, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15119, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1294
Score = 120 bits (289), Expect(2) = 1e-47
Identities = 45/80 (56%), Positives = 64/80 (80%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P + KE +IFGN+++++ FH +FL+EL+KYE +PEDVGHCFVTWA +F MYVSYC+
Sbjct: 33 IPAGIVNKEHIIFGNMQDLYEFHHNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVSYCK 92
Query: 188 NKPDSNAAVVQHAGDYFERV 247
NKPDS +++HAG YF+ +
Sbjct: 93 NKPDSTQLILEHAGAYFDEL 112
Score = 97.5 bits (232), Expect = 2e-19
Identities = 47/111 (42%), Positives = 69/111 (62%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H+ FL EL+K P+ + F+ R MY+ YC+
Sbjct: 671 VPDDMRGKDKIVFGNIHQIYDWHKDFFLGELEKCLENPDRLAPLFIKQERRLHMYIVYCQ 730
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
NKP S V ++ YFE ++++ + LIKPVQRI KYQLLLKDL
Sbjct: 731 NKPKSEHIVSEYIDTYFEDLKQRLGHRLQITDLLIKPVQRIMKYQLLLKDL 781
Score = 92.7 bits (220), Expect(2) = 1e-47
Identities = 46/81 (56%), Positives = 55/81 (67%)
Frame = +2
Query: 335 DLQACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGP 514
+L CC EG+GEIKDGLEVMLSVPKKANDAMHLS+LEG D DS GE++LQ P
Sbjct: 111 ELLTCCEEGKGEIKDGLEVMLSVPKKANDAMHLSMLEGFDGNIDSQGELILQESFQVWDP 170
Query: 515 SSDHQKGTREESLLFDLHLAF 577
+ +KG LF++ L F
Sbjct: 171 KTLIRKGRDRHLFLFEMSLVF 191
>UniRef50_UPI0000F34917 Cluster: UPI0000F34917 related cluster; n=2;
Bos taurus|Rep: UPI0000F34917 UniRef100 entry - Bos
Taurus
Length = 821
Score = 145 bits (351), Expect = 9e-34
Identities = 77/177 (43%), Positives = 113/177 (63%), Gaps = 5/177 (2%)
Frame = +2
Query: 20 LQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPD 199
LQ K+D++FGN+EEI+ FH R+FLREL+ Y PE VG CF+ EF +Y YC+NKP
Sbjct: 508 LQNKKDILFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEEFQIYEKYCQNKPR 567
Query: 200 SNAAVVQHAG-DYFERVQRKKKLEHPLA--AYLIKPVQRITKYQLLLKDL--QACCAEGQ 364
S + Q + +F+ Q KKL+H L+ +YL+KPVQRITKYQLLLK++ + EG
Sbjct: 568 SESLWRQCSDCPFFQECQ--KKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSKSCEGA 625
Query: 365 GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKG 535
++++ L +L + K ND+MHL + G + LG +++QG S +DH++G
Sbjct: 626 EDLQEALSSILGILKAVNDSMHLIAITGYEGNLSDLGRLLMQGSFS---VWTDHKRG 679
>UniRef50_Q4S0P7 Cluster: Chromosome 2 SCAF14781, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1108
Score = 143 bits (346), Expect = 4e-33
Identities = 76/181 (41%), Positives = 114/181 (62%), Gaps = 5/181 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P PLQ K++++FGN+ EI+ FH+R FLREL++Y PE VG CF+ + +Y YC
Sbjct: 586 IPAPLQNKKEVLFGNMSEIYHFHKRTFLRELEQYTDCPELVGRCFLQRMTDLQIYEKYCH 645
Query: 188 NKPDSNAAVVQHAG-DYFERVQRKKKLEHPLA--AYLIKPVQRITKYQLLLKDL--QACC 352
NKP S + Q + +F+ Q KKLEH L +YL+KPVQRITKYQLLLK++ +
Sbjct: 646 NKPRSESLWRQCSDCAFFQECQ--KKLEHKLGLDSYLLKPVQRITKYQLLLKEMLKYSKT 703
Query: 353 AEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQK 532
EG ++++ L +L + K ND+MHL + G + LG++++QG S ++H+K
Sbjct: 704 CEGADDLQEALASILGILKAVNDSMHLIAITGYEGNLSELGKLLMQGSFS---VWTEHKK 760
Query: 533 G 535
G
Sbjct: 761 G 761
>UniRef50_O15068 Cluster: Guanine nucleotide exchange factor DBS;
n=69; Euteleostomi|Rep: Guanine nucleotide exchange
factor DBS - Homo sapiens (Human)
Length = 1137
Score = 142 bits (345), Expect = 5e-33
Identities = 74/175 (42%), Positives = 110/175 (62%), Gaps = 3/175 (1%)
Frame = +2
Query: 20 LQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPD 199
L K+D++FGN+EEI+ FH R+FLREL+ Y PE VG CF+ +F +Y YC+NKP
Sbjct: 674 LHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPR 733
Query: 200 SNAAVVQHAG-DYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL--QACCAEGQGE 370
S + Q + +F+ QRK + L +YL+KPVQRITKYQLLLK++ + EG +
Sbjct: 734 SESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAED 793
Query: 371 IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKG 535
+++ L +L + K ND+MHL + G D LG++++QG S +DH++G
Sbjct: 794 LQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFS---VWTDHKRG 845
>UniRef50_Q4SUB9 Cluster: Chromosome 3 SCAF13974, whole genome shotgun
sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 3
SCAF13974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2492
Score = 118 bits (284), Expect = 1e-25
Identities = 64/164 (39%), Positives = 99/164 (60%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P ++GK+ ++FGNI++I+ +H FL EL++ + + F+ R MYV YC+
Sbjct: 2070 IPEDMRGKDKIVFGNIQQIYDWHRDFFLVELERCLQNHDLLADLFIRHERRLHMYVVYCQ 2129
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQ 364
NKP S V+++ +FE +Q + ++ YLIKP+QRITKYQLLLKD L+ G
Sbjct: 2130 NKPRSEFLVIEYE-KFFEEIQHEISCRMSVSDYLIKPIQRITKYQLLLKDFLKYTSKAGL 2188
Query: 365 G--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
EI+ LE+M VPK+ ND M+L L+G + S G+++ Q
Sbjct: 2189 DCEEIEKALELMSLVPKRCNDMMNLGRLQGYEGKLTSQGKLLQQ 2232
Score = 83.8 bits (198), Expect(2) = 5e-32
Identities = 39/65 (60%), Positives = 49/65 (75%)
Frame = +2
Query: 140 FVTWAREFDMYVSYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKY 319
FV A +F MYV+YCRNKPDS+ + QH +FE VQR+ L + +++ LIKPVQRITKY
Sbjct: 1376 FVCQADKFHMYVTYCRNKPDSSLLIQQHGVGFFEEVQRRHGLANSVSSALIKPVQRITKY 1435
Query: 320 QLLLK 334
QLLLK
Sbjct: 1436 QLLLK 1440
Score = 77.0 bits (181), Expect(2) = 5e-32
Identities = 29/48 (60%), Positives = 39/48 (81%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTW 151
VP L K+D++FGNI++I+ FH +FL+EL+ YE +PEDVGHCFVTW
Sbjct: 1303 VPPGLVNKDDIVFGNIQDIYEFHNSIFLKELENYEQLPEDVGHCFVTW 1350
Score = 69.3 bits (162), Expect(2) = 9e-12
Identities = 29/39 (74%), Positives = 37/39 (94%)
Frame = +2
Query: 332 KDLQACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEG 448
++L ACC EG+GEIK+GL+VMLSVPK+ANDAMH+S+LEG
Sbjct: 1483 QELLACCEEGKGEIKEGLDVMLSVPKRANDAMHVSMLEG 1521
Score = 23.0 bits (47), Expect(2) = 9e-12
Identities = 16/48 (33%), Positives = 25/48 (52%)
Frame = +2
Query: 473 GEVVLQGLLSRVGPSSDHQKGTREESLLFDLHLAFWRKK*RIPTGKTQ 616
GE++LQ P S +KG LF+L L F K+ + +G+T+
Sbjct: 1560 GELLLQDSFLVWEPKSLIRKGRDRHLFLFELSLIF-SKEIKDSSGRTK 1606
>UniRef50_Q4RY59 Cluster: Chromosome 3 SCAF14978, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 3
SCAF14978, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1113
Score = 132 bits (319), Expect = 7e-30
Identities = 69/155 (44%), Positives = 102/155 (65%), Gaps = 5/155 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P LQ K+D++FGN+ EI++FH+R FL+EL+ Y PE VG CF+ ++ +Y +YC+
Sbjct: 601 IPNSLQNKKDILFGNMSEIYQFHKRTFLKELEAYTDCPELVGRCFLERMKDLQIYEAYCQ 660
Query: 188 NKPDSNAAVVQHAG-DYFERVQRKKKLEHPLA--AYLIKPVQRITKYQLLLKDL--QACC 352
NKP S + Q + +F+ Q KKLEH L +YL+KPVQRITKYQLLLK+L +
Sbjct: 661 NKPRSESLWRQCSDCAFFQECQ--KKLEHKLGLDSYLLKPVQRITKYQLLLKELLKYSRG 718
Query: 353 AEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDV 457
EG ++++ L +L + K ND+MHL + G +V
Sbjct: 719 CEGCDDLQEALTSILGILKAVNDSMHLIAITGYEV 753
>UniRef50_O61528 Cluster: Guanine nucleotide exchange factor UNC-73A;
n=7; Caenorhabditis|Rep: Guanine nucleotide exchange
factor UNC-73A - Caenorhabditis elegans
Length = 2488
Score = 130 bits (314), Expect = 3e-29
Identities = 70/187 (37%), Positives = 105/187 (56%), Gaps = 5/187 (2%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF-DMYVSYCRNKPDSNAAVV 217
IFGNIE+I +FH L EL KYE PE VG F+ W ++Y YC NK N +
Sbjct: 1254 IFGNIEKIFKFHNDKLLHELIKYENQPEAVGASFIVWIDLLNELYTEYCVNKEQKNHVIA 1313
Query: 218 Q-HAGDYFERVQRKKKLE--HPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLE 388
A +F ++ + LE + +A+ LIKPVQRIT+Y+LL++ L C + ++K+ E
Sbjct: 1314 TPDAVSFFTGIRERHGLEINNEIASLLIKPVQRITRYRLLIEQLMRSCTDKTNDLKEAYE 1373
Query: 389 VMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQ-KGTREESLLFDL 565
V+ SVP+K ND +H + L+ D D LG V Q L+ P + + +G + LFD+
Sbjct: 1374 VVCSVPRKVNDLIHYNCLDLKDFKVDELGPFVTQDTLTFWEPRAYFKGRGKERQVFLFDI 1433
Query: 566 HLAFWRK 586
+ F ++
Sbjct: 1434 SIVFAKR 1440
Score = 106 bits (255), Expect = 4e-22
Identities = 66/170 (38%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF-DMYVSYC 184
+P L GK+ +IF NI I FH+ FL+E++K E G FV + R +YV+YC
Sbjct: 1844 LPADLVGKDKIIFANIVNILEFHKTNFLKEIEKCSENYEAAGAAFVKYERRLHTLYVTYC 1903
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAA--YLIKPVQRITKYQLLLKDLQACCAE 358
+NKP S+ + Q + F K KL H +A LIKPVQRI KYQLLLKD+
Sbjct: 1904 QNKPKSDYLLAQDDFEAF-FADTKAKLGHKVALCDLLIKPVQRIMKYQLLLKDILKFTER 1962
Query: 359 GQGE---IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLL 499
+ + +K L+VM VPK +D M + L+ D + G+++ QG L
Sbjct: 1963 AKDKTDTLKKALQVMHVVPKACDDMMQVGRLQNFDKSLSAQGKLIHQGTL 2012
>UniRef50_P10911 Cluster: Proto-oncogene DBL (Proto-oncogene MCF-2)
[Contains: MCF2-transforming protein; DBL-transforming
protein]; n=36; Tetrapoda|Rep: Proto-oncogene DBL
(Proto-oncogene MCF-2) [Contains: MCF2-transforming
protein; DBL-transforming protein] - Homo sapiens (Human)
Length = 925
Score = 130 bits (313), Expect = 3e-29
Identities = 68/165 (41%), Positives = 99/165 (60%), Gaps = 3/165 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+ K+D++FGN+ EI+ FH +FL L+ PE VG CF+ +F MY YC+
Sbjct: 534 MPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDDFQMYAKYCQ 593
Query: 188 NKPDSNAAVVQHAG-DYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL--QACCAE 358
NKP S +++ +F+ QRK K L +YL+KPVQRITKYQLLLK+L + E
Sbjct: 594 NKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYSKDCE 653
Query: 359 GQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQG 493
G +K L+ ML + K ND+MH + G + LG++++QG
Sbjct: 654 GSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQG 698
>UniRef50_UPI000065F563 Cluster: Homolog of Brachydanio rerio
"Quattro.; n=1; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Quattro. - Takifugu rubripes
Length = 1628
Score = 125 bits (301), Expect = 1e-27
Identities = 63/167 (37%), Positives = 96/167 (57%), Gaps = 4/167 (2%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY 181
A VP L+G+ +IFGN+E++H FH+ FL EL+ P VG C + F +Y Y
Sbjct: 1318 ADVPQDLRGQRGIIFGNLEKLHDFHQHHFLSELEGCVNEPFRVGRCVLRHVESFALYALY 1377
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
+NKP S+A + H +F++ Q K + L +YL+KPVQRI+KY LLL+D+ A C G
Sbjct: 1378 SKNKPQSDALFISHGQSFFKQKQLKLGDKMDLWSYLLKPVQRISKYSLLLQDMMADCGPG 1437
Query: 362 Q----GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
Q E+K LEV+ + N+ + + ++ CDV G+++ Q
Sbjct: 1438 QSREMAEVKAALEVIHFQLRHGNNLLAMDAIQHCDVNLKEQGQLIRQ 1484
>UniRef50_Q96PX9 Cluster: KIAA1909 protein; n=12; Euteleostomi|Rep:
KIAA1909 protein - Homo sapiens (Human)
Length = 1287
Score = 124 bits (300), Expect = 1e-27
Identities = 65/164 (39%), Positives = 101/164 (61%), Gaps = 6/164 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+GK +IFGN+E++H FH++ FLREL++ + P VG F+ +F MYV Y +
Sbjct: 856 LPQGLRGKHHVIFGNLEKLHDFHQQHFLRELERCQHCPLAVGRSFLRHEEQFGMYVIYSK 915
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL--QACC--A 355
NKP S+A + H +F+ QR+ + LA+YL++PVQR+ KY LLL+DL +A C A
Sbjct: 916 NKPQSDALLSSHGNAFFKDKQRELGDKMDLASYLLRPVQRVAKYALLLQDLLKEASCGLA 975
Query: 356 EGQ--GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEV 481
+GQ GE++ V+ + ND + + + GCDV G++
Sbjct: 976 QGQELGELRAAEVVVCFQLRHGNDLLAMDAIRGCDVNLKEQGQL 1019
>UniRef50_UPI000058400D Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 565
Score = 124 bits (299), Expect = 2e-27
Identities = 68/164 (41%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+GK ++FGN+E+I+ FH RVFLREL T P VG CF+ +EF +Y Y
Sbjct: 78 IPQALRGKRSIVFGNLEKIYHFHSRVFLRELKGCMTTPLQVGQCFLKHRQEFGLYALYNM 137
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL-QACCAEGQ 364
NKP S++ + G +F QR+ K LA+YL+KPVQR+ KY LLL+DL + C E Q
Sbjct: 138 NKPRSDSLLADF-GHFFRSKQRRLKDSMDLASYLLKPVQRLGKYALLLRDLIRQCGTEDQ 196
Query: 365 GEIK-DGLEVMLSVP-KKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+ EVM+ + ND + + L+ CDV GE++ Q
Sbjct: 197 EQNHLRAAEVMIEFQMRHGNDLLAMDSLQDCDVNLREQGELIRQ 240
>UniRef50_Q4RP67 Cluster: Chromosome 1 SCAF15008, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1263
Score = 87.0 bits (206), Expect(2) = 9e-27
Identities = 50/118 (42%), Positives = 71/118 (60%), Gaps = 4/118 (3%)
Frame = +2
Query: 161 FDMYVSYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLA--AYLIKPVQRITKYQLLLK 334
F MY YC+NKP S+A Q + +F + + +K LEH L +YL+KPVQR+TKYQLLLK
Sbjct: 887 FQMYECYCQNKPRSDALWRQFSDCHFFQ-ECQKNLEHKLGLDSYLLKPVQRLTKYQLLLK 945
Query: 335 DL--QACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLS 502
+L + +G E++ L ML + K ND+MH + G + LG V++QG S
Sbjct: 946 ELLKYSTDCKGTSELQGALTAMLDLLKSVNDSMHQIAITGYEGDICELGRVLMQGSFS 1003
Score = 56.0 bits (129), Expect(2) = 9e-27
Identities = 23/57 (40%), Positives = 38/57 (66%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVS 178
+P L K+D++FGN+ EI+ FH R+FL++L+ PE VG CF+ R+ ++V+
Sbjct: 793 LPPILHSKQDILFGNMPEIYNFHSRIFLQDLEGCLETPESVGACFLERVRQRKLFVN 849
>UniRef50_UPI00015B606E Cluster: PREDICTED: similar to
ENSANGP00000031634; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000031634 - Nasonia
vitripennis
Length = 820
Score = 120 bits (290), Expect = 2e-26
Identities = 73/198 (36%), Positives = 107/198 (54%), Gaps = 8/198 (4%)
Frame = +2
Query: 8 VPLPLQ---GKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVS 178
+PLP GK+ ++FGNIE ++ +H FL+ L+ PE++G F + R+ MYV
Sbjct: 505 IPLPDDLKGGKDKMVFGNIEAMYEWHRDCFLKSLEHCLERPEELGPLFKRYERKLHMYVV 564
Query: 179 YCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACC-- 352
YC+NKP S V ++ YFE +++K L LIKPVQRITKYQLLL++
Sbjct: 565 YCQNKPVSEYIVSEYIDTYFEELRQKLGHRLQLCDLLIKPVQRITKYQLLLREALRLTQR 624
Query: 353 AEGQGEIKD---GLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSD 523
Q EI+ VM +PK AND M + L+G D + G+++L G L SS
Sbjct: 625 THRQSEIEGLTAAAHVMHVIPKAANDMMDVGRLQGFDGKITAQGKLLLHGPLMVAELSSL 684
Query: 524 HQKGTREESLLFDLHLAF 577
+G + LF+ ++ F
Sbjct: 685 PSRGREWQVFLFEQNIIF 702
>UniRef50_UPI0000F211CF Cluster: PREDICTED: similar to RAC/CDC42
exchange factor; n=3; Danio rerio|Rep: PREDICTED:
similar to RAC/CDC42 exchange factor - Danio rerio
Length = 749
Score = 118 bits (285), Expect = 9e-26
Identities = 62/164 (37%), Positives = 95/164 (57%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P ++GK+ ++FGNI +I+ +H+ FL EL+K PE + F+ R MYV YC+
Sbjct: 362 IPEDMKGKDKIVFGNIHQIYDWHKDYFLAELEKCVAEPERLAQLFIKHERRLHMYVVYCQ 421
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG-- 361
NKP S V ++ YFE ++++ L LIKPVQRI KYQLLLKD +
Sbjct: 422 NKPKSEHIVSEYIETYFEELKQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFHKYYTKAGM 481
Query: 362 -QGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
E++ +EVM VPK+ ND M++ L+G + + G+++ Q
Sbjct: 482 DTEELEKAVEVMCFVPKRCNDMMNVGRLQGFEGKITAQGKLLQQ 525
>UniRef50_Q1RLV0 Cluster: Zgc:136817; n=3; Danio rerio|Rep:
Zgc:136817 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 471
Score = 118 bits (284), Expect = 1e-25
Identities = 66/164 (40%), Positives = 98/164 (59%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP + GK+ ++FGNI +I+ +H+ FL EL+K + + F+ R MYV YC+
Sbjct: 82 VPEDMTGKDKIVFGNIHQIYDWHKEFFLCELEKCLQDHDKLAELFIKHERRLHMYVIYCQ 141
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQ 364
NKP S V ++ YFE VQ++ ++ YLIKP+QRITKYQLLLKD L+ G
Sbjct: 142 NKPRSEFVVAEY-DKYFEGVQQEINSRLAISDYLIKPIQRITKYQLLLKDFLKYSTKAGL 200
Query: 365 G--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
EI+ +E+M VPK+ ND M+L L+G + + G+++ Q
Sbjct: 201 DCKEIEKAVELMSLVPKQCNDMMNLGRLQGYEGKLTAQGKLLQQ 244
>UniRef50_UPI0000DB73BC Cluster: PREDICTED: similar to Guanine
nucleotide exchange factor DBS (DBLs big sister) (MCF2
transforming sequence-like protein); n=2; Apocrita|Rep:
PREDICTED: similar to Guanine nucleotide exchange factor
DBS (DBLs big sister) (MCF2 transforming sequence-like
protein) - Apis mellifera
Length = 1340
Score = 118 bits (283), Expect = 2e-25
Identities = 74/181 (40%), Positives = 106/181 (58%), Gaps = 6/181 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWARE--FDMYVSY 181
+P L GK D++FGN+E+I+ FH FL++L+ + E V CFV RE F +Y Y
Sbjct: 910 IPAVLIGKGDILFGNLEDIYIFHGETFLKDLENCISNTELVALCFVQ-RREVFFRLYSYY 968
Query: 182 CRNKPDSNAA--VVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCA 355
C+N P S +Q+ + Q++ + PLAAYL+KPVQRITKYQLLLKDL
Sbjct: 969 CQNIPRSERLREQIQNEPQFLAACQQRLGHKLPLAAYLLKPVQRITKYQLLLKDLLKYSD 1028
Query: 356 EGQ--GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQ 529
E E+++ L+ ML V K ND+MH + + G ++ GE++LQG S V SS +
Sbjct: 1029 EPSCCTELQEALDCMLVVLKCVNDSMHQTAITGFGGDLNAQGELLLQGSFS-VWSSSKRE 1087
Query: 530 K 532
+
Sbjct: 1088 R 1088
>UniRef50_Q4SVF8 Cluster: Chromosome 7 SCAF13760, whole genome shotgun
sequence; n=2; Tetraodontidae|Rep: Chromosome 7
SCAF13760, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 942
Score = 118 bits (283), Expect = 2e-25
Identities = 70/167 (41%), Positives = 98/167 (58%), Gaps = 5/167 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L ++DL+FGN+ EI++ VFL++L PE VG CF+ +F +Y YC+
Sbjct: 579 LPSALHSQKDLLFGNMPEIYQ----VFLQDLQGCLETPERVGSCFLQRKEKFQVYERYCQ 634
Query: 188 NKPDSNAAVVQHAGD-YFERVQRKKKLEHPLA--AYLIKPVQRITKYQLLLKDLQACCAE 358
NKP S Q +F+ Q KKLEH L +YL+KPVQR+TKYQLLLK+L C E
Sbjct: 635 NKPRSELLWRQCCDSPFFQECQ--KKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKHCRE 692
Query: 359 G--QGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQG 493
+ ++++ L+ ML + K ND+MH + G LG VVLQG
Sbjct: 693 ERYRQQLQEALDSMLELLKSVNDSMHQIAITGYQGDLSQLGRVVLQG 739
>UniRef50_Q7Z2K2 Cluster: Transforming gene product TGAT; n=2;
Eutheria|Rep: Transforming gene product TGAT - Homo
sapiens (Human)
Length = 255
Score = 118 bits (283), Expect = 2e-25
Identities = 61/152 (40%), Positives = 90/152 (59%), Gaps = 3/152 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H FL EL+K PE +G FV R MY++YC+
Sbjct: 84 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQ 143
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ- 364
NKP S V ++ +FE ++++ L LIKPVQRI KYQLLLKD +
Sbjct: 144 NKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL 203
Query: 365 --GEIKDGLEVMLSVPKKANDAMHLSLLEGCD 454
E++ +EVM VP++ ND M++ L+G D
Sbjct: 204 DTSELERAVEVMCIVPRRCNDMMNVGRLQGFD 235
>UniRef50_Q9Y2A5 Cluster: Serine/threonine-protein kinase Duet;
n=20; Mammalia|Rep: Serine/threonine-protein kinase Duet
- Homo sapiens (Human)
Length = 1289
Score = 117 bits (282), Expect = 2e-25
Identities = 67/194 (34%), Positives = 110/194 (56%), Gaps = 4/194 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H+ FL EL+K + + F+ R+ +YV YC+
Sbjct: 267 VPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQ 326
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ- 364
NKP S V ++ YFE V+++ L+ +LIKP+QRITKYQLLLKD +
Sbjct: 327 NKPRSEYIVAEYDA-YFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGL 385
Query: 365 --GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGT 538
+I+ +E+M VPK+ ND M+L L+G + + G+++ Q + + Q T
Sbjct: 386 ECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRT 445
Query: 539 REESL-LFDLHLAF 577
+E + LF+ + F
Sbjct: 446 KERRVFLFEQIVIF 459
>UniRef50_Q6DN89 Cluster: Quattro; n=2; Eumetazoa|Rep: Quattro - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1989
Score = 117 bits (281), Expect = 3e-25
Identities = 63/167 (37%), Positives = 97/167 (58%), Gaps = 6/167 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP L+G+ LIFGN+E++ FH+ F++EL+ P VG CF+ F +Y Y +
Sbjct: 1540 VPQDLRGQRGLIFGNLEKLRDFHQHHFIQELELCLEKPFSVGRCFLKHKESFGLYALYSK 1599
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACC----- 352
NKP S ++QH D+F++ Q++ K L++YL+KPVQRI+KY LLL+DL C
Sbjct: 1600 NKPRSENLLIQHGKDFFKQKQQQLKDALDLSSYLLKPVQRISKYSLLLQDLLRECECVTN 1659
Query: 353 AEGQ-GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
AE Q EI L ++ + N+ + + + GCDV G+++ Q
Sbjct: 1660 AELQRTEIHTALNIIQFQLRHGNNLLAMDDIYGCDVNLKEQGQLIRQ 1706
>UniRef50_Q16L87 Cluster: Dbl; n=3; Fungi/Metazoa group|Rep: Dbl -
Aedes aegypti (Yellowfever mosquito)
Length = 1538
Score = 116 bits (279), Expect = 5e-25
Identities = 70/166 (42%), Positives = 93/166 (56%), Gaps = 5/166 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF-DMYVSYC 184
VP LQGK D++FGN+ E++ FH +FL++L+ + E V CFV F +Y YC
Sbjct: 1069 VPPGLQGKADILFGNLHELYTFHNDIFLKDLENCISTTELVALCFVQRRDTFFRLYSYYC 1128
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAE 358
+N P S + + +KKL H PLAAYL+KPVQRITKYQLLLKDL
Sbjct: 1129 QNIPRSERLRETLVDTHLFLQECQKKLGHKLPLAAYLLKPVQRITKYQLLLKDLLKFSDT 1188
Query: 359 G--QGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
G E++ L+ ML V K ND+MH + G GE++LQ
Sbjct: 1189 GTCSRELQKALDCMLVVLKCVNDSMHQIAITGFPADLSQQGELLLQ 1234
>UniRef50_UPI0000D55959 Cluster: PREDICTED: similar to CG18214-PD,
isoform D; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG18214-PD, isoform D - Tribolium castaneum
Length = 1411
Score = 115 bits (277), Expect = 8e-25
Identities = 63/173 (36%), Positives = 99/173 (57%), Gaps = 8/173 (4%)
Frame = +2
Query: 8 VPLP---LQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVS 178
+P+P GK+ ++FGNIE I+ +H+ +FL+ L K P ++ F + R+ MYV
Sbjct: 457 IPMPEDLRDGKDKMVFGNIEAIYDWHKDIFLKSLKKAIENPTELAQLFRRYERKLHMYVV 516
Query: 179 YCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL-----Q 343
YC+NKP S V ++ YFE ++ K + L LIKPVQRI KYQL+LKD+ +
Sbjct: 517 YCKNKPVSEYIVSEYLESYFEELRVKLGHKLQLCDLLIKPVQRIMKYQLMLKDILKYTER 576
Query: 344 ACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLS 502
A ++ ++M+ +PK AND M + L+G D + G+++L G L+
Sbjct: 577 AGLTAEAEPLRTAYQIMVDLPKAANDMMDVGRLQGFDGKITAQGKLLLHGPLT 629
>UniRef50_UPI00004D56CF Cluster: Puratrophin-1 (Pleckstrin homology
domain-containing family G member 4) (Purkinje cell
atrophy-associated protein 1).; n=1; Xenopus
tropicalis|Rep: Puratrophin-1 (Pleckstrin homology
domain-containing family G member 4) (Purkinje cell
atrophy-associated protein 1). - Xenopus tropicalis
Length = 1025
Score = 114 bits (275), Expect = 1e-24
Identities = 60/165 (36%), Positives = 93/165 (56%), Gaps = 4/165 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+GK +IFGN+E++ FH + FL+EL+ P V HCF+ +F MY Y +
Sbjct: 599 LPQDLRGKRGIIFGNLEKLRDFHSQYFLKELESCCNHPLRVSHCFLRHKDQFGMYALYSK 658
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP S+A + H +F+ Q + LA+YL+KP+QR++KY LLLKDL C E Q
Sbjct: 659 NKPRSDALLGSHGNIFFKNKQCLLGDKMDLASYLLKPIQRMSKYALLLKDLIKECEEAQE 718
Query: 368 E----IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+ ++ E++ + ND + + + CDV G++V Q
Sbjct: 719 QELAYLRAAEEMVKFQLRHGNDLLAMDAIRDCDVNLKEQGQLVRQ 763
>UniRef50_UPI0000F1E6F8 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1671
Score = 114 bits (274), Expect = 2e-24
Identities = 58/167 (34%), Positives = 95/167 (56%), Gaps = 4/167 (2%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY 181
A +P L+GK +IFGN+E++ FH + FL+EL+ P V HCF+ +F +Y Y
Sbjct: 1200 ADLPQDLRGKRSVIFGNLEKLVDFHSQYFLKELESCCNHPLRVSHCFLRHQDQFSLYALY 1259
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
+NKP S+ + H ++F+ Q + + LA+YL+KP+QR++KY LLLKDL +E
Sbjct: 1260 SKNKPKSDTLLASHGNNFFKHKQMELGDKMDLASYLLKPIQRMSKYALLLKDLIKEVSEV 1319
Query: 362 QGE----IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
Q + ++ E++ + ND + + + CDV G++V Q
Sbjct: 1320 QEQELTYLRAAAEMVKFQLRHGNDLLAMDAIRDCDVNLKEQGQLVRQ 1366
>UniRef50_UPI0000F1E2DD Cluster: PREDICTED: similar to RAC/CDC42
exchange factor; n=3; Danio rerio|Rep: PREDICTED:
similar to RAC/CDC42 exchange factor - Danio rerio
Length = 640
Score = 113 bits (273), Expect = 2e-24
Identities = 62/164 (37%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP L+GK+ ++FGNI +I+ +H+ FL EL+K + P+ + F+ R +MYV YC+
Sbjct: 305 VPEYLEGKDKIVFGNIHQIYDWHKDYFLGELEKCVSEPDLLAQLFIKHERRLNMYVVYCQ 364
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
N P S V ++ YFE ++++ L LIKPVQRI KYQLLLKD +
Sbjct: 365 NMPKSEHIVSEYIETYFEDLRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYTKAGR 424
Query: 368 EIKD---GLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+ +D +EVM VPK+ ND M++ L+G + + G+++ Q
Sbjct: 425 QTEDLERAVEVMCFVPKRCNDMMNVGRLQGFEGQLRAQGKLLQQ 468
>UniRef50_UPI000065F2B5 Cluster: Huntingtin-associated
protein-interacting protein (Protein Duo).; n=2;
Euteleostomi|Rep: Huntingtin-associated
protein-interacting protein (Protein Duo). - Takifugu
rubripes
Length = 2988
Score = 113 bits (272), Expect = 3e-24
Identities = 62/164 (37%), Positives = 97/164 (59%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H F+ EL+K E + F+ R MYV YC+
Sbjct: 2019 VPDDMKGKDKIVFGNIHQIYDWHREFFVGELEKCLDDHEHLPELFIKHERRLHMYVIYCQ 2078
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQ 364
NKP S V ++ YF+ +Q+ + ++ +LIKP+QRITKYQLLLKD L+ G
Sbjct: 2079 NKPKSEFIVAEY-DTYFDGIQQDIQSRLTISDFLIKPIQRITKYQLLLKDFLKFSSKAGM 2137
Query: 365 G--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+I+ +++M VPK ND M+L L+G + S G+++ Q
Sbjct: 2138 DCEQIEKAVDLMSQVPKLCNDMMNLGRLQGYEGKLTSQGKLLQQ 2181
Score = 94.3 bits (224), Expect = 2e-18
Identities = 64/207 (30%), Positives = 103/207 (49%), Gaps = 1/207 (0%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAR-EFDMYVSYC 184
+P + KE +IFGN+++I+ FH +FL+EL YE +PEDVGHCFVTW + +
Sbjct: 1348 IPPGIANKEHIIFGNMQDIYDFHNNIFLKELINYEQLPEDVGHCFVTWVSVSINSGYFFI 1407
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
++ + D F K P ++ LI + + +L +CC EG+
Sbjct: 1408 LMVVNTYPSTFFPQADKFHIYVDYCK-NKPDSSQLI-----LEQAGTFFDELLSCCEEGK 1461
Query: 365 GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTRE 544
GEIKDGL+++L+ ++ SL G + + GE++LQ P S +KG
Sbjct: 1462 GEIKDGLDLVLTSHLSFFFSLS-SLPSGFEENLEVQGELILQDSFQVWDPRSLIRKGRDR 1520
Query: 545 ESLLFDLHLAFWRKK*RIPTGKTQIHF 625
LF+ L F K+ + G+T+ +
Sbjct: 1521 HLFLFEFSLVF-SKEIKDSAGRTKYQY 1546
>UniRef50_Q4RTS6 Cluster: Chromosome 2 SCAF14997, whole genome
shotgun sequence; n=3; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF14997, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1334
Score = 111 bits (268), Expect = 1e-23
Identities = 60/153 (39%), Positives = 92/153 (60%), Gaps = 3/153 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H F+ EL+K E + F+ R MYV YC+
Sbjct: 238 VPDDMKGKDKIVFGNIHQIYDWHREFFVGELEKCLDDHEHLPELFIKHERRLHMYVIYCQ 297
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQ 364
NKP S V ++ YF+ +Q+ + ++ +LIKP+QRITKYQLLLKD L+ G
Sbjct: 298 NKPKSEFIVAEY-DTYFDGIQQDIQSRLTISDFLIKPIQRITKYQLLLKDFLKFSSKAGM 356
Query: 365 G--EIKDGLEVMLSVPKKANDAMHLSLLEGCDV 457
+I+ +++M VPK ND M+L L+G +V
Sbjct: 357 DCEQIEKAVDLMSQVPKLCNDMMNLGRLQGYEV 389
>UniRef50_A7SVF8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 792
Score = 111 bits (266), Expect = 2e-23
Identities = 65/165 (39%), Positives = 87/165 (52%), Gaps = 4/165 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P+ L + + IFGNIEEI FH FL EL+K P+ VG F EF+ Y YC+
Sbjct: 521 IPIELFDQRETIFGNIEEILEFHRCDFLEELNKCSETPKSVGKVFTERRGEFEKYALYCK 580
Query: 188 NKPDSNAAVVQHAG-DYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
NKP S A Q Y Q + PL AYL+KPVQRITKYQLLL+++ +
Sbjct: 581 NKPASEALQQQLINVPYIRECQANLGHKLPLTAYLLKPVQRITKYQLLLREMMKNTKNDR 640
Query: 365 ---GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+ + M +V + ND MH S L+G LG+++LQ
Sbjct: 641 IAYMNLMEAFHAMQNVLRHLNDVMHSSGLKGYHGNLGDLGKLLLQ 685
>UniRef50_A0NEN5 Cluster: ENSANGP00000031634; n=2; Culicidae|Rep:
ENSANGP00000031634 - Anopheles gambiae str. PEST
Length = 541
Score = 111 bits (266), Expect = 2e-23
Identities = 71/189 (37%), Positives = 102/189 (53%), Gaps = 5/189 (2%)
Frame = +2
Query: 26 GKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSN 205
GKE ++FGNIE I+ +H FL+ L K P ++G R+ MYV YC+NKP S
Sbjct: 262 GKERMVFGNIEAIYEWHRDHFLKALQKCLQNPYELGPLIKRSERKLHMYVVYCQNKPVSE 321
Query: 206 AAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-----LQACCAEGQGE 370
V +H YF+ ++ K K + L LIKPVQRI KY+LLLKD L+A E
Sbjct: 322 HIVQEHM-SYFDELRLKLKYKLCLGDMLIKPVQRIMKYELLLKDILKHTLRAGLTEEVPG 380
Query: 371 IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTREES 550
+K+ + +M VPK AND M + L+ + + G+++L G L S + QK
Sbjct: 381 LKEAMHIMQVVPKAANDMMDVGRLQKFEGKITTQGKLLLHGPL--YCNSYNSQKPKELHV 438
Query: 551 LLFDLHLAF 577
LF+ ++ F
Sbjct: 439 FLFEQNIIF 447
>UniRef50_UPI0000F2B983 Cluster: PREDICTED: similar to FLJ00068
protein; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to FLJ00068 protein - Monodelphis domestica
Length = 1760
Score = 110 bits (265), Expect = 2e-23
Identities = 58/173 (33%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY 181
A VP L+G+ +FGN+E++ FH FLREL+ P V H F+ +F +Y Y
Sbjct: 1307 ADVPQVLRGQRAQLFGNLEKLWDFHRHFFLRELESCSQHPLRVAHAFLRHREQFGLYALY 1366
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
+NKP S+ + H +F+ QR+ LA+YL+KP+QR++KY LLL++L C EG
Sbjct: 1367 SKNKPRSDMLLASHGNAFFKDKQRQLGDHLDLASYLLKPIQRMSKYALLLQELSQTCEEG 1426
Query: 362 QG----------EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
G ++ +++ + ND + + + GCDV G++V Q
Sbjct: 1427 PGPSWAREPDLAALRAARDLVRFQLRHGNDLLAMDAIRGCDVNLKEQGQLVRQ 1479
>UniRef50_Q7K4E0 Cluster: LD43457p; n=2; Sophophora|Rep: LD43457p -
Drosophila melanogaster (Fruit fly)
Length = 1057
Score = 109 bits (262), Expect = 5e-23
Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 5/167 (2%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF-DMYVSY 181
S P LQGK +++FGN+ EI+ FH VFL++L+ ++ E V CFV +F +Y Y
Sbjct: 653 SAPASLQGKANVLFGNLNEIYSFHNDVFLKDLENCISVTERVALCFVKRRDKFYQLYSFY 712
Query: 182 CRN--KPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCA 355
C+N + + + +F+ Q + PL AYL+KPVQRITKYQLLLKDL
Sbjct: 713 CQNIQRSEKLRETLVDTHMFFKECQIGLGHKLPLGAYLLKPVQRITKYQLLLKDLLLFTD 772
Query: 356 EG--QGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+ E+K+ L+ ML V K ND+MH + G GE+++Q
Sbjct: 773 NDSCRNELKNALDCMLIVLKCVNDSMHQISITGFSGDLAKQGELLMQ 819
>UniRef50_UPI0000F21533 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1652
Score = 109 bits (261), Expect = 7e-23
Identities = 58/165 (35%), Positives = 92/165 (55%), Gaps = 4/165 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP L+G+ IFGN+E+++ FH + F +EL + P G CF+ F +Y Y +
Sbjct: 1209 VPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSK 1268
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP S+A + H YF+R Q + L++YL+KPVQRI+KY LLL+++ C Q
Sbjct: 1269 NKPQSDALIQHHR--YFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQS 1326
Query: 368 ----EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
EI+ LEV+ + ND + + + CD+ + G+++ Q
Sbjct: 1327 PEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQ 1371
>UniRef50_UPI00015A5797 Cluster: UPI00015A5797 related cluster; n=1;
Danio rerio|Rep: UPI00015A5797 UniRef100 entry - Danio
rerio
Length = 1772
Score = 109 bits (261), Expect = 7e-23
Identities = 58/165 (35%), Positives = 92/165 (55%), Gaps = 4/165 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP L+G+ IFGN+E+++ FH + F +EL + P G CF+ F +Y Y +
Sbjct: 1431 VPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSK 1490
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP S+A + H YF+R Q + L++YL+KPVQRI+KY LLL+++ C Q
Sbjct: 1491 NKPQSDALIQHHR--YFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQS 1548
Query: 368 ----EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
EI+ LEV+ + ND + + + CD+ + G+++ Q
Sbjct: 1549 PEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQ 1593
>UniRef50_UPI00015B51B1 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1155
Score = 108 bits (260), Expect = 9e-23
Identities = 57/165 (34%), Positives = 96/165 (58%), Gaps = 4/165 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+G+ ++IFGN+E+I+ FH + FLREL++ E P VG CF+ ++F +Y Y +
Sbjct: 694 IPQSLRGQRNVIFGNVEKIYEFHSQYFLRELEQCEQSPMMVGQCFLRHEKKFYLYALYNK 753
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP+S++ + ++ +F+ Q + + LA+YL+KPVQR+ KY LLL+ L +
Sbjct: 754 NKPNSDSLMAEYGTAFFKAKQMELGDKMDLASYLLKPVQRMGKYALLLQQLVKAGTDLSE 813
Query: 368 EIKDGL---EVMLSVP-KKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
++ L E M+ + ND + + L CDV G ++ Q
Sbjct: 814 QLSADLRAAEQMVRFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQ 858
>UniRef50_Q86VW2 Cluster: RhoA/RAC/CDC42 exchange factor; n=52;
Tetrapoda|Rep: RhoA/RAC/CDC42 exchange factor - Homo
sapiens (Human)
Length = 580
Score = 108 bits (260), Expect = 9e-23
Identities = 62/164 (37%), Positives = 93/164 (56%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP L+G++ ++FGNI++I+ +H FL+EL + P+ + F+ R MYV Y +
Sbjct: 195 VPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYYQ 254
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQ 364
NKP S V + YFE ++++ L LIKPVQRI KYQLLLKD L+ G
Sbjct: 255 NKPKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGM 314
Query: 365 --GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
+++ +EVM VPK+ ND M L L G + + G+++ Q
Sbjct: 315 DTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQ 358
>UniRef50_Q7KU89 Cluster: CG33275-PA, isoform A; n=7; Diptera|Rep:
CG33275-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1876
Score = 106 bits (255), Expect = 4e-22
Identities = 59/172 (34%), Positives = 94/172 (54%), Gaps = 11/172 (6%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P PL+G+ ++IFGNIE+I FH FL EL++YE P VG F+ +F +Y Y +
Sbjct: 1356 IPQPLRGQRNVIFGNIEKIFEFHNSHFLGELERYERNPLKVGAAFLEMESKFYLYALYNK 1415
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP S+ + ++ +F+ Q + + + LA+YL+KPVQR+ KY LLL+ L C +G
Sbjct: 1416 NKPKSDTLLSEYGSSFFKPKQMQLQDKLDLASYLLKPVQRMGKYALLLQQLVKACKGVEG 1475
Query: 368 -----------EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
E++ E++ + ND + + L CDV G ++ Q
Sbjct: 1476 AALQEIAADVEELQRAEEMVKFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQ 1527
>UniRef50_UPI0000E80D31 Cluster: PREDICTED: hypothetical protein;
n=2; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 1260
Score = 74.5 bits (175), Expect(2) = 4e-22
Identities = 31/78 (39%), Positives = 48/78 (61%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+GK +IFGN+E+++ FH + FLREL+ P V HCF+ +F MY Y +
Sbjct: 746 LPQDLRGKRSVIFGNLEKLYDFHSQYFLRELESCCNHPLRVSHCFLRHKDQFGMYALYSK 805
Query: 188 NKPDSNAAVVQHAGDYFE 241
NKP S++ + H +F+
Sbjct: 806 NKPKSDSLLASHGNTFFK 823
Score = 52.8 bits (121), Expect(2) = 4e-22
Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 4/94 (4%)
Frame = +2
Query: 236 FERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ----GEIKDGLEVMLSV 403
F++VQ K++ LA+YL+KP+QR++KY LLLKDL C+E Q G ++ E++
Sbjct: 855 FKQVQLGDKMD--LASYLLKPIQRMSKYALLLKDLIKECSEAQEQELGYLRAAEEMVKFQ 912
Query: 404 PKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSR 505
+ ND + + + CD + QG L R
Sbjct: 913 LRHGNDLLAMDAIRDCDAVPCGQVNLKEQGQLVR 946
>UniRef50_UPI00005A5680 Cluster: PREDICTED: similar to pleckstrin
homology domain containing, family G (with RhoGef domain)
member 4; n=2; Canis lupus familiaris|Rep: PREDICTED:
similar to pleckstrin homology domain containing, family
G (with RhoGef domain) member 4 - Canis familiaris
Length = 1405
Score = 106 bits (254), Expect = 5e-22
Identities = 58/167 (34%), Positives = 91/167 (54%), Gaps = 6/167 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+GK ++FGN+E ++ FH + FL EL++ + P G F+ +F MY Y +
Sbjct: 968 LPQDLRGKHSIVFGNLENLYDFHRQHFLAELERCQHCPLAAGRGFLRHEEQFGMYALYSK 1027
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL----QACCA 355
NKP S+A + H +F+ QR+ + LA+YL+KPVQR+ KY LLL+DL C
Sbjct: 1028 NKPQSDALLCSHGNAFFKDKQRQLGDKMDLASYLLKPVQRMGKYALLLQDLVREAGRCPV 1087
Query: 356 EGQ--GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
Q E++ V+ + ND + + + GCDV G++ Q
Sbjct: 1088 PEQELSELRAAQGVVRFQLRHGNDLLAMDAVRGCDVNLKEQGQLRCQ 1134
>UniRef50_UPI0001554F5B Cluster: PREDICTED: similar to FLJ00068
protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to FLJ00068 protein - Ornithorhynchus anatinus
Length = 1384
Score = 104 bits (249), Expect = 2e-21
Identities = 49/127 (38%), Positives = 77/127 (60%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P PL+G+ +FGN+E++ FH FLREL+ P V + F+ +F MY Y +
Sbjct: 915 LPQPLRGQRARLFGNLEKLSDFHRNFFLRELESCAQHPLRVANAFLRHREQFGMYALYTK 974
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP S+ + H +F++ Q++ LA+YL+KP+QR++KY LLL++L C EG+
Sbjct: 975 NKPKSDVLMASHGNAFFKKKQQQLGDRLDLASYLLKPIQRMSKYALLLRELARACGEGR- 1033
Query: 368 EIKDGLE 388
+ GLE
Sbjct: 1034 --EQGLE 1038
>UniRef50_UPI0000519A5C Cluster: PREDICTED: similar to CG33275-PC,
isoform C isoform 1; n=1; Apis mellifera|Rep: PREDICTED:
similar to CG33275-PC, isoform C isoform 1 - Apis
mellifera
Length = 1121
Score = 103 bits (246), Expect = 5e-21
Identities = 46/111 (41%), Positives = 78/111 (70%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+G+ ++IFGN+E+I+ FH + FLREL++ E P +VG CF+ ++F +Y Y +
Sbjct: 649 IPQALRGQRNVIFGNVEKIYEFHGQHFLRELEQCEQSPMNVGQCFLRHEKKFYLYALYNK 708
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
NKP+S++ + ++ +F++ Q + + LA+YL+KPVQR+ KY LLL+ L
Sbjct: 709 NKPNSDSLMAEYGTAFFKQKQLELGDKMDLASYLLKPVQRMGKYALLLQQL 759
>UniRef50_Q4S810 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
SCAF14710, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 442
Score = 101 bits (243), Expect = 1e-20
Identities = 47/113 (41%), Positives = 71/113 (62%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY 181
A VP L+GK +IFGN+E++H FH FL EL+ E V CF+ + F +Y Y
Sbjct: 37 ADVPQDLRGKRGVIFGNLEKLHDFHSHYFLPELEACEREAAMVARCFLRHSESFGLYALY 96
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+NKP S+A ++ D F+R Q++ L++YL++P+QRI+KY LLL+D+
Sbjct: 97 SKNKPQSDALILHRPHDIFKRKQQELGDLMDLSSYLLRPIQRISKYSLLLQDV 149
>UniRef50_Q17DQ5 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1433
Score = 101 bits (243), Expect = 1e-20
Identities = 65/199 (32%), Positives = 101/199 (50%), Gaps = 15/199 (7%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+G+ ++IFGNIE I FH++ FL EL+ E P VG F+ +F +Y Y +
Sbjct: 906 IPQALRGQRNVIFGNIERICEFHQQHFLSELESCEHHPIKVGSAFLRHESKFYLYALYNK 965
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ- 364
NKP S++ + ++ +F+ Q + + LA+YL+KPVQR+ KY LLL+ L C+ Q
Sbjct: 966 NKPKSDSLMSENGTQFFKAKQMELNDKMDLASYLLKPVQRMGKYALLLQQLMKACSAAQE 1025
Query: 365 ---GEIKDGLEVMLSVP-------KKANDAMHLSLLEGCDVPTDSLGEVVLQGLL----S 502
EI + +E + + ND + + L CDV G ++ Q
Sbjct: 1026 TTNPEILEDMEELQKAEEMVRFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQNEFLVWEG 1085
Query: 503 RVGPSSDHQKGTREESLLF 559
+ G S Q EE +LF
Sbjct: 1086 KAGKKSLRQVFLFEELVLF 1104
>UniRef50_Q58EX7 Cluster: Puratrophin-1; n=18; Eutheria|Rep:
Puratrophin-1 - Homo sapiens (Human)
Length = 1191
Score = 101 bits (241), Expect = 2e-20
Identities = 56/164 (34%), Positives = 87/164 (53%), Gaps = 3/164 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP L+G+ +FGN+E++ FH FLREL+ P V + F+ +F MY Y +
Sbjct: 767 VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSK 826
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
NKP S+A + + +F+ Q+ LA+YL+KP+QR+ KY LLL++L C
Sbjct: 827 NKPRSDALMSSYGHTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQ 886
Query: 368 EIKDGLEVMLSVP---KKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
E+ E V + ND + + ++GCDV G++V Q
Sbjct: 887 ELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQ 930
>UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG33519-PB - Apis mellifera
Length = 1306
Score = 94.7 bits (225), Expect = 2e-18
Identities = 51/164 (31%), Positives = 89/164 (54%), Gaps = 5/164 (3%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++ +D+IF N+++I FH V + + Y P +G F+ R+FD +V+YCR
Sbjct: 60 VPRAVRDNKDIIFTNLKQIADFHNTVLIEGVKYYADQPRMLGKTFLRLERDFDKHVAYCR 119
Query: 188 NKPDSNAAVVQH--AGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL---QACC 352
++P + + + +YFE + + + + L+ +L P+QRI YQLLLK+L
Sbjct: 120 DEPAAQEFLQMNDVVREYFEELSQTLRDDKSLSEHLKLPIQRINDYQLLLKELVKYSTRL 179
Query: 353 AEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVV 484
E +++ LE+ML +P +A D +S +EG LG ++
Sbjct: 180 GENCDDLQKALELMLGIPHRATDNKFISNIEGYKGNIHKLGRLL 223
>UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to
ENSANGP00000021721; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021721 - Nasonia
vitripennis
Length = 1247
Score = 92.3 bits (219), Expect = 9e-18
Identities = 50/165 (30%), Positives = 89/165 (53%), Gaps = 5/165 (3%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYC 184
+VP ++ +++IF N+++I FH V + + Y P +G F+ R+FD +V+YC
Sbjct: 60 AVPRAVRDNKEIIFTNLKQIAEFHNTVLIEGVKYYADQPRMLGKTFLRLERDFDKHVAYC 119
Query: 185 RNKPDSNAAVVQH--AGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL---QAC 349
R++P + + + +YFE + K + ++ +L P+QRI YQLLLK+L
Sbjct: 120 RDEPVAQDFLQSNNEVREYFEELSHKLGDDKSVSEHLKLPIQRINDYQLLLKELVKYSTR 179
Query: 350 CAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVV 484
E +++ LE+ML +P +A D +S +EG LG ++
Sbjct: 180 LGEDCDDLQKALELMLGIPHRATDNKFISNIEGYKGNIHKLGRLL 224
>UniRef50_A7SFH2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1005
Score = 90.2 bits (214), Expect = 3e-17
Identities = 47/113 (41%), Positives = 66/113 (58%), Gaps = 2/113 (1%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF--DMYV 175
AS P L+G + IF NI++IH +H F L E MP +G F T+A ++Y
Sbjct: 354 ASAPSELKGNQKFIFSNIQDIHDWHANKFYTFLKDCEDMPSQLGDVF-TYAESKLEELYT 412
Query: 176 SYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLK 334
YCRNKP S++ V+ + +F+ + + + YLIKPVQRITKYQLLL+
Sbjct: 413 VYCRNKPKSDSLVMTYKDTFFQECRHRLGHRLQITDYLIKPVQRITKYQLLLR 465
>UniRef50_Q86YR7 Cluster: Rho family guanine-nucleotide exchange
factor; n=10; Eutheria|Rep: Rho family
guanine-nucleotide exchange factor - Homo sapiens
(Human)
Length = 1031
Score = 88.6 bits (210), Expect = 1e-16
Identities = 47/113 (41%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P LQ +D +FGNI E++ FH R FL+EL+K PE + HCF+ + +Y Y +
Sbjct: 575 IPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAENPELLAHCFLKRKEDLQIYFKYHK 634
Query: 188 NKPDSNAAVVQHAGD--YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
N P + A+ Q D YF QR+ PL YL P QR+ KYQ+LLK L
Sbjct: 635 NLPRAR-AIWQECQDCAYFGVCQRQLDHNLPLFKYLKGPSQRLIKYQMLLKGL 686
>UniRef50_UPI0000EB3077 Cluster: pleckstrin homology domain
containing, family G, member 3; n=3; Canis lupus
familiaris|Rep: pleckstrin homology domain containing,
family G, member 3 - Canis familiaris
Length = 1224
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/123 (41%), Positives = 76/123 (61%), Gaps = 5/123 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+FGNIE I+ + ++ LR+LD + P V CFV ++EFD+Y YC N P+S AA+ +
Sbjct: 137 LFGNIENIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTE 195
Query: 221 HAGDYFERV---QRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGL 385
D + R++ L+H PL +YL+KPVQRI KY LLL+++ A+ E +DG
Sbjct: 196 CMRDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEI----AKHFDEEEDGF 251
Query: 386 EVM 394
EV+
Sbjct: 252 EVV 254
>UniRef50_A1L390 Cluster: Pleckstrin homology domain-containing
family G member 3; n=4; Homo/Pan/Gorilla group|Rep:
Pleckstrin homology domain-containing family G member 3
- Homo sapiens (Human)
Length = 1219
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/123 (41%), Positives = 76/123 (61%), Gaps = 5/123 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+FGNIE I+ + ++ LR+LD + P V CFV ++EFD+Y YC N P+S AA+ +
Sbjct: 138 LFGNIENIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTE 196
Query: 221 HAGDYFERV---QRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGL 385
D + R++ L+H PL +YL+KPVQRI KY LLL+++ A+ E +DG
Sbjct: 197 CMRDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEI----AKHFDEEEDGF 252
Query: 386 EVM 394
EV+
Sbjct: 253 EVV 255
>UniRef50_Q4VAC9 Cluster: Pleckstrin homology domain-containing
family G member 3; n=21; Tetrapoda|Rep: Pleckstrin
homology domain-containing family G member 3 - Mus
musculus (Mouse)
Length = 1341
Score = 86.6 bits (205), Expect = 4e-16
Identities = 50/123 (40%), Positives = 76/123 (61%), Gaps = 5/123 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+FGNIE I+ + ++ LR+LD + P V CFV ++EFD+Y YC N P+S AA+ +
Sbjct: 138 LFGNIESIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTE 196
Query: 221 HAGDYFERV---QRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGL 385
D + R++ L+H PL +YL+KPVQR+ KY LLL+++ A+ E +DG
Sbjct: 197 CMQDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRVLKYHLLLQEI----AKHFDEEEDGF 252
Query: 386 EVM 394
EV+
Sbjct: 253 EVV 255
>UniRef50_Q4SEW8 Cluster: Chromosome undetermined SCAF14611, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14611, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1152
Score = 84.6 bits (200), Expect = 2e-15
Identities = 64/200 (32%), Positives = 98/200 (49%), Gaps = 32/200 (16%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY 181
A +P L+GK ++FGN+E++ FH + FL+EL+ P HCF+ +F +Y Y
Sbjct: 707 ADLPQDLRGKRSVVFGNLEKLLDFHSQYFLKELEACWKHPLRAPHCFLRHQEQFGLYALY 766
Query: 182 CRNKPDSNAAVVQHAGDYFERVQ----------------------RKKKLE----HPLAA 283
+NKP S+A + H ++F RV+ + K++E L++
Sbjct: 767 SKNKPKSDALLASHGTEFF-RVRSASPCEGAADPILNVCLGSSGSQGKQMELGDKMDLSS 825
Query: 284 YLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPK----KANDAMHLSLLEGC 451
YL+KPVQR++KY LLL DL + Q L+ S+ K ND + + + C
Sbjct: 826 YLLKPVQRMSKYALLLTDLMKEVSSSQEAELSTLQAATSMVKFQLRHGNDLLAMDAIREC 885
Query: 452 DVPTDSLGEVVL--QGLLSR 505
DV S +V L QG L R
Sbjct: 886 DVDLCSSLQVNLKEQGQLIR 905
>UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14556, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2646
Score = 84.2 bits (199), Expect = 2e-15
Identities = 51/173 (29%), Positives = 97/173 (56%), Gaps = 12/173 (6%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN 190
P + +++ IF NIE+I FH RVF +L++ ET +DV CF+ F+ Y+ Y
Sbjct: 1924 PSEVSSQKEAIFRNIEDIKSFHNRVFFSKLNECET-DDDVAMCFLKNKEGFEKYMQYLVG 1982
Query: 191 KPDSNAAVVQHA-----GDYFERVQRKKKLE----HPLAAYLIKPVQRITKYQLLLKDL- 340
+ + +AV +Y +++Q K E H ++AYL +P++RI KY+++LK+L
Sbjct: 1983 QSPAESAVGDRTVHRFFKEYTDKIQAGKAPEDPAVHSVSAYLQQPLERIQKYKVVLKELI 2042
Query: 341 QACCAEGQG--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQG 493
+ GQ +++ ++ ++P+++ ++ H+S++E + LGE + QG
Sbjct: 2043 RNKARNGQNCCLLEEAYAMVSALPQRSENSHHVSMIENYPATLEVLGEPIRQG 2095
>UniRef50_Q9ULL1 Cluster: Pleckstrin homology domain-containing
family G member 1; n=29; Eumetazoa|Rep: Pleckstrin
homology domain-containing family G member 1 - Homo
sapiens (Human)
Length = 1385
Score = 83.8 bits (198), Expect = 3e-15
Identities = 51/145 (35%), Positives = 77/145 (53%), Gaps = 9/145 (6%)
Frame = +2
Query: 14 LPLQGKE-DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN 190
LPL +E +FGNI++I+ F+ + L++L+ E P + CFV+ + EF +Y YC N
Sbjct: 149 LPLGTEERSALFGNIQDIYHFNSEL-LQDLENCENDPVAIAECFVSKSEEFHIYTQYCTN 207
Query: 191 KPDSNAAVVQHAGD-----YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACC- 352
P S A + + + +F Q K PL +YL+KPVQRI KY LLL +++
Sbjct: 208 YPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLD 267
Query: 353 --AEGQGEIKDGLEVMLSVPKKAND 421
EG + D ++ M V ND
Sbjct: 268 KDTEGYDVVLDAIDTMQRVAWHIND 292
>UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep:
Obscurin-MLCK - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 2009
Score = 83.0 bits (196), Expect = 5e-15
Identities = 58/211 (27%), Positives = 102/211 (48%), Gaps = 12/211 (5%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VPL + +++ IF NI +I FHE L +L+ + +DV CFV +A +F+MY+ +
Sbjct: 34 VPLTILSQKEYIFRNIRDIASFHECCILPKLEMCFS-DDDVAQCFVGYAADFEMYLQFIT 92
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEH------PLAAYLIKPVQRITKYQLLLKDLQAC 349
P + A + +F + +L + YL +P++RI Y+ +LK++
Sbjct: 93 GLPQAEACISDKNTQHFFKQYANIELADLDTQVFSVGTYLQRPMERIETYKTVLKEMIRN 152
Query: 350 CAE-GQG--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLS---RVG 511
A+ GQ ++D ++ S+P +A + HLS++E P LGE + QG + +
Sbjct: 153 KAKSGQNCCLLEDAFAMVSSLPWRAENLHHLSMIENYPAPLKGLGEPIRQGHFTAWEEIP 212
Query: 512 PSSDHQKGTREESLLFDLHLAFWRKK*RIPT 604
Q+G LF + F + K + T
Sbjct: 213 EVKSSQRGHHRHVFLFKDCIVFCKPKREVGT 243
>UniRef50_Q4RLN1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 729
Score = 81.4 bits (192), Expect = 2e-14
Identities = 47/135 (34%), Positives = 72/135 (53%), Gaps = 8/135 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVV- 217
+FGNIE+I+ F+ + L+ LD ++ P + CFV + F +Y YC N P+S AA+
Sbjct: 167 LFGNIEDIYEFNSEL-LQSLDMCDSDPVAIAQCFVDKSEYFQIYTQYCTNYPNSVAALTD 225
Query: 218 ----QHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQA---CCAEGQGEIK 376
+ +F Q K PL +YL+KPVQRI KY LLL+++ EG ++
Sbjct: 226 CMRNKTLAKFFRDRQASLKCSLPLGSYLLKPVQRILKYHLLLQEIAKHLDLHEEGYEVVQ 285
Query: 377 DGLEVMLSVPKKAND 421
+ ++ M V ND
Sbjct: 286 EAIDTMTGVAWYIND 300
>UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin - Homo
sapiens (Human)
Length = 7968
Score = 81.4 bits (192), Expect = 2e-14
Identities = 59/209 (28%), Positives = 105/209 (50%), Gaps = 15/209 (7%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP+ + G++ +IF N+ +I RFH FL+EL + +T +DV CF+ F+ Y+ +
Sbjct: 5729 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDT-DDDVAMCFIKNQAAFEQYLEFLV 5786
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKL---------EHPLAAYLIKPVQRITKYQLLLKDL 340
+ + + VV A F + ++ L PL YL +PV+R+ +YQ LLK+L
Sbjct: 5787 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 5846
Query: 341 ---QACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQG--LLSR 505
+A + ++ V+ ++P++A + +H+SL+E +LGE + QG ++
Sbjct: 5847 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHFIVWE 5906
Query: 506 VGPSSDHQ-KGTREESLLFDLHLAFWRKK 589
P + KG LF HL + +
Sbjct: 5907 GAPGARMPWKGHNRHVFLFRNHLVICKPR 5935
>UniRef50_Q4S6V2 Cluster: Chromosome 14 SCAF14723, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF14723, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1484
Score = 81.0 bits (191), Expect = 2e-14
Identities = 46/109 (42%), Positives = 67/109 (61%), Gaps = 6/109 (5%)
Frame = +2
Query: 32 EDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
++ +FGNI++I+ F+ R L EL+K P + CFV+ + EF +Y YC N P S AA
Sbjct: 151 KEALFGNIQDIYHFN-RDLLHELEKCHADPVAIAECFVSKSEEFHIYTQYCTNYPRSVAA 209
Query: 212 VVQ----HAGDYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDL 340
+ + A F R +R++ L H PL +YL+KPVQRI KY LLL ++
Sbjct: 210 LTECMRNKALAKFFR-ERQESLRHSLPLGSYLLKPVQRILKYHLLLHEI 257
>UniRef50_UPI0000F210AF Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1446
Score = 79.4 bits (187), Expect = 6e-14
Identities = 49/138 (35%), Positives = 79/138 (57%), Gaps = 6/138 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+FGNI +I+RF+ + LR+L+K P + CFV + +F +Y YC N P S A + +
Sbjct: 177 LFGNIRDIYRFNSEL-LRDLEKCNANPVAIAKCFVAKSEDFHIYTQYCTNYPRSVAVLTE 235
Query: 221 HAGD----YFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDG 382
+ F R +R++ L+H PL +YL+KPVQRI KY LLL ++ A E E+ D
Sbjct: 236 CMRNKMVAKFLR-ERQESLKHSLPLGSYLLKPVQRILKYHLLLHEI-ATHLEKDSEMYDV 293
Query: 383 LEVMLSVPKKANDAMHLS 436
++ + ++ A H++
Sbjct: 294 IQEAIDTMQRV--AWHIN 309
>UniRef50_UPI00015A58C2 Cluster: Pleckstrin homology
domain-containing family G member 1.; n=1; Danio
rerio|Rep: Pleckstrin homology domain-containing family
G member 1. - Danio rerio
Length = 1281
Score = 79.4 bits (187), Expect = 6e-14
Identities = 49/138 (35%), Positives = 79/138 (57%), Gaps = 6/138 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+FGNI +I+RF+ + LR+L+K P + CFV + +F +Y YC N P S A + +
Sbjct: 134 LFGNIRDIYRFNSEL-LRDLEKCNANPVAIAKCFVAKSEDFHIYTQYCTNYPRSVAVLTE 192
Query: 221 HAGD----YFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDG 382
+ F R +R++ L+H PL +YL+KPVQRI KY LLL ++ A E E+ D
Sbjct: 193 CMRNKMVAKFLR-ERQESLKHSLPLGSYLLKPVQRILKYHLLLHEI-ATHLEKDSEMYDV 250
Query: 383 LEVMLSVPKKANDAMHLS 436
++ + ++ A H++
Sbjct: 251 IQEAIDTMQRV--AWHIN 266
>UniRef50_UPI000065FF36 Cluster: Homolog of Homo sapiens "pleckstrin
homology domain containing, family G (with RhoGef
domain) member 3 (PLEKHG3), mRNA; n=3;
Clupeocephala|Rep: Homolog of Homo sapiens "pleckstrin
homology domain containing, family G (with RhoGef
domain) member 3 (PLEKHG3), mRNA - Takifugu rubripes
Length = 2512
Score = 77.4 bits (182), Expect = 3e-13
Identities = 48/135 (35%), Positives = 72/135 (53%), Gaps = 8/135 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+FGNIE+I+ F+ + L+ LD + V CF+ F++Y YC N P+S AA+ +
Sbjct: 55 LFGNIEDIYEFNSEL-LQALDLCDNDAVAVARCFIMKGEFFEIYTQYCTNYPNSVAALTE 113
Query: 221 -----HAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL-QACCAEGQG--EIK 376
+F Q K PL +YL+KPVQRI KY LLL+++ + E QG ++
Sbjct: 114 CMRKKSLATFFRERQASLKCSLPLGSYLLKPVQRILKYHLLLQEIAKHFDPEEQGYEVVE 173
Query: 377 DGLEVMLSVPKKAND 421
+ + M SV ND
Sbjct: 174 EAIYTMTSVAWYIND 188
>UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin - Mus
musculus (Mouse)
Length = 8891
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/174 (28%), Positives = 89/174 (51%), Gaps = 12/174 (6%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP + ++ +IF N+++I FH FL+EL T +DV CF+ F+ Y+ +
Sbjct: 6669 VPAAVASQKTVIFRNVQDISHFHSS-FLKELQGCGT-DDDVAMCFIKNQEAFEKYLEFLV 6726
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEH---------PLAAYLIKPVQRITKYQLLLKDL 340
+ + + VV F + ++ L PL YL +PV+R+ KYQ LLK+L
Sbjct: 6727 GRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKEL 6786
Query: 341 ---QACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQG 493
+A + ++ V+ ++P++A + +H+SL+E ++LGE + QG
Sbjct: 6787 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQG 6840
>UniRef50_Q17LU2 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 1450
Score = 73.7 bits (173), Expect = 3e-12
Identities = 45/128 (35%), Positives = 71/128 (55%), Gaps = 5/128 (3%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA-- 208
+++F NI+EI F+ R+ L L++ + P + CF+ FD Y +YC P++ A
Sbjct: 481 EILFSNIQEIWDFNSRL-LDRLNETKGDPVKISGCFIDLHENFDCYTTYCTRYPEAIALL 539
Query: 209 -AVVQHAGDYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKD 379
+++Q + +K L H PL +YL+KPVQRI KY LLL +L+ C + Q +
Sbjct: 540 TSLLQATHTNALLIHTQKMLNHNLPLGSYLLKPVQRILKYHLLLDNLRKHCDDKQ--VSH 597
Query: 380 GLEVMLSV 403
E+M SV
Sbjct: 598 AHELMKSV 605
>UniRef50_O02133 Cluster: Temporarily assigned gene name protein
150, isoform b; n=3; Caenorhabditis|Rep: Temporarily
assigned gene name protein 150, isoform b -
Caenorhabditis elegans
Length = 638
Score = 72.9 bits (171), Expect = 6e-12
Identities = 52/168 (30%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY- 181
S+P L+GK D +FGN+ E+++FH R L +L + E C V +YV+Y
Sbjct: 279 SLPDTLRGKPDCLFGNVRELYKFHHRTVLEDLVAARSTAE---MCRVLMQHRNQIYVTYR 335
Query: 182 --CRNKPDSNAAVVQHAGD--YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQA 346
C+ SN V + +F+ QR +++YL+KP+QRI KYQLLL + +
Sbjct: 336 TYCQIH-GSNQKVRDSVKNHPFFKECQRNANHNMDMSSYLLKPIQRIMKYQLLLGNIMDD 394
Query: 347 CCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
C A+ + E+ + M+ + + + +M + G + SLG + LQ
Sbjct: 395 CPADVRDEVAMTRDSMVELLNQIDASMQQLHISGYNGDLKSLGLLRLQ 442
>UniRef50_A1ZBA1 Cluster: CG30115-PD, isoform D; n=4; Sophophora|Rep:
CG30115-PD, isoform D - Drosophila melanogaster (Fruit
fly)
Length = 1593
Score = 71.7 bits (168), Expect = 1e-11
Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAV- 214
++F NIEEI+ F+ + L+ L P + CF+ FD+Y +YC + P++ + +
Sbjct: 628 ILFANIEEIYEFNS-MLLQRLINTGRDPGRIARCFIDLRDGFDVYTTYCTSYPEAISLLT 686
Query: 215 --VQHAGDYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDG 382
+Q Y +K L+H PL +YL+KPVQRI KY LLL L+ C ++K+
Sbjct: 687 KLLQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHC-----DVKEV 741
Query: 383 LEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQKGTREESLLFD 562
+E + + + A++ + + L +L G L GP R+E LL +
Sbjct: 742 VEAHVIMRQVAHNIDQVKRKQEQQSRVKELSG-ILDGWL---GPELTVLGELRQEGLLME 797
Query: 563 LH 568
H
Sbjct: 798 QH 799
>UniRef50_Q4SB72 Cluster: Chromosome undetermined SCAF14677, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14677,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 856
Score = 70.1 bits (164), Expect = 4e-11
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 11/147 (7%)
Frame = +2
Query: 14 LPLQGKE-DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN 190
LPL+ ++ +F NIE+I+ F+ + L +L++ + + CFV + FD+Y YC N
Sbjct: 68 LPLKPEQVSTLFCNIEDIYEFNSDL-LEDLERSQHAAA-IAECFVERSEAFDIYTLYCMN 125
Query: 191 KPDSNAAV-----VQHAGDYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQAC 349
P S A + + +F+ +R+ L H PL YL+KPVQRI KY LLL++L
Sbjct: 126 YPSSVAVLRECMNTRSLAQFFQ--ERRTTLNHSLPLETYLLKPVQRILKYHLLLQELSKH 183
Query: 350 CAE---GQGEIKDGLEVMLSVPKKAND 421
+ G ++D + M +V ND
Sbjct: 184 FDKSDPGYEVVEDAIVTMTAVAWYIND 210
>UniRef50_A0NBJ0 Cluster: ENSANGP00000029817; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000029817 - Anopheles gambiae
str. PEST
Length = 1684
Score = 69.7 bits (163), Expect = 5e-11
Identities = 39/114 (34%), Positives = 67/114 (58%), Gaps = 5/114 (4%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA--- 208
++F NI+E++ F+ ++ L L + + P + +CF+ EF Y +YC + P++ +
Sbjct: 580 VLFSNIQEVYDFNFKL-LNRLREAKGDPVTISNCFIDLHAEFCCYTTYCTSYPEAISLLT 638
Query: 209 AVVQHAGDYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
++Q V +K L+H PL +YL+KPVQRI KY LLL +L+ C++ Q
Sbjct: 639 TLLQATHTNALLVSTQKMLKHTLPLGSYLLKPVQRILKYHLLLDNLRKHCSDQQ 692
>UniRef50_Q9H7P9 Cluster: Pleckstrin homology domain-containing
family G member 2; n=24; Euteleostomi|Rep: Pleckstrin
homology domain-containing family G member 2 - Homo
sapiens (Human)
Length = 1386
Score = 69.7 bits (163), Expect = 5e-11
Identities = 41/114 (35%), Positives = 63/114 (55%), Gaps = 5/114 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+F NIE+I+ F + L +L+ + + CFV + +FD+Y YC N P S A + +
Sbjct: 148 LFANIEDIYEFSSEL-LEDLEN-SSSAGGIAECFVQRSEDFDIYTLYCMNYPSSLALLRE 205
Query: 221 -----HAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
A + + Q + + PL ++L+KPVQRI KY LLL++L AEG G
Sbjct: 206 LSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPG 259
>UniRef50_UPI0000DA3D65 Cluster: PREDICTED: similar to mcf.2
transforming; n=1; Rattus norvegicus|Rep: PREDICTED:
similar to mcf.2 transforming - Rattus norvegicus
Length = 600
Score = 69.3 bits (162), Expect = 7e-11
Identities = 28/65 (43%), Positives = 41/65 (63%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+ K+D++FGN+ EI+ FH +F+ L+ PE VG CF+ +F MY YC+
Sbjct: 372 MPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLERKEDFQMYAKYCQ 431
Query: 188 NKPDS 202
NKP S
Sbjct: 432 NKPRS 436
>UniRef50_Q4RXW9 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14979, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 511
Score = 68.9 bits (161), Expect = 9e-11
Identities = 31/78 (39%), Positives = 46/78 (58%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
VP ++GK+ ++FGNI +I+ +H+ FL EL+K P+ + F+ R MYV YC+
Sbjct: 84 VPEDMRGKDRMVFGNIHQIYDWHKDYFLGELEKCLADPDSLAQLFIKHERRLHMYVVYCQ 143
Query: 188 NKPDSNAAVVQHAGDYFE 241
NKP S V + YFE
Sbjct: 144 NKPKSEHIVSEFIETYFE 161
>UniRef50_UPI0000D55943 Cluster: PREDICTED: similar to Pleckstrin
homology domain-containing family G member 1; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to Pleckstrin
homology domain-containing family G member 1 - Tribolium
castaneum
Length = 1421
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/132 (34%), Positives = 69/132 (52%), Gaps = 6/132 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+F N+EEI+RF+ R FL +L + P + + F+ F +Y YC N P + + +
Sbjct: 633 LFSNLEEIYRFN-RSFLDQLRAADFNPTKIANVFIQNDSGFAVYNEYCTNYPRTMEVLSE 691
Query: 221 HAGDY-FERVQRKKK--LEH--PLAAYLIKPVQRITKYQLLLKDL-QACCAEGQGEIKDG 382
D + R+K+ L H PL +YL+KPVQRI KY LLL+ L + C + + +
Sbjct: 692 LTRDEKMASLFREKQMALSHALPLGSYLLKPVQRILKYHLLLQRLSKQCDTDHKPAVDLA 751
Query: 383 LEVMLSVPKKAN 418
L M +V N
Sbjct: 752 LATMTAVASSIN 763
>UniRef50_Q7QGJ0 Cluster: ENSANGP00000019802; n=4; Culicidae|Rep:
ENSANGP00000019802 - Anopheles gambiae str. PEST
Length = 309
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/114 (29%), Positives = 66/114 (57%), Gaps = 2/114 (1%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAR--EFDMYVS 178
++P L+G++ IFGNIE+IH H+ FL L+ + F+ + +F Y+
Sbjct: 34 NLPPGLRGQKYHIFGNIEKIHNLHQNQFLPMLESNRASIAGIAETFIWFLENDKFYCYIM 93
Query: 179 YCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ N+P S ++ D+F+R Q++ + L ++L++P+QR+ +Y+LLL ++
Sbjct: 94 FALNRPKSERICNKNL-DFFQRRQQEVDDKLGLNSFLLQPIQRLPRYKLLLAEI 146
>UniRef50_UPI000065DEA3 Cluster: Homolog of Brachydanio rerio
"Quattro.; n=2; Euteleostomi|Rep: Homolog of Brachydanio
rerio "Quattro. - Takifugu rubripes
Length = 413
Score = 64.9 bits (151), Expect = 1e-09
Identities = 46/156 (29%), Positives = 82/156 (52%), Gaps = 4/156 (2%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCR 187
+P L+GK +IFGN+E++ FH + FL++L E HC + +S C
Sbjct: 36 LPQDLRGKRSIIFGNVEKLWDFHTQYFLKDL-------ESCAHC--------PLSISSC- 79
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ- 364
++H ++++ K++ LA+YL+KP+QR++KY LLLKDL C++ Q
Sbjct: 80 --------FLRHN----KQIELGDKMD--LASYLLKPIQRMSKYALLLKDLIKECSQSQE 125
Query: 365 ---GEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPT 463
+++ +++ + ND + + + GCD PT
Sbjct: 126 QELSDLRTAEDMVKFQLRHGNDLLAMDAIRGCDDPT 161
>UniRef50_UPI000051ACFC Cluster: PREDICTED: similar to Pleckstrin
homology domain-containing family G member 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pleckstrin homology
domain-containing family G member 1 - Apis mellifera
Length = 1354
Score = 63.3 bits (147), Expect = 5e-09
Identities = 45/141 (31%), Positives = 67/141 (47%), Gaps = 15/141 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVV- 217
+F NIE+I F+ R FL+E+++ P V + F+ F +Y YC N P + + +
Sbjct: 303 LFSNIEDIFEFN-REFLKEIEECGLDPVSVANTFIKHKSGFKVYTEYCTNYPSTVSVLTD 361
Query: 218 ----QHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQ----ACC------A 355
+ F+ Q K PL ++L+ PVQRI KY LLL++L A C
Sbjct: 362 LMSQEKTACAFQERQAALKHALPLGSFLLTPVQRILKYHLLLENLSKEYAADCEVRENKT 421
Query: 356 EGQGEIKDGLEVMLSVPKKAN 418
EG I+ L M + K N
Sbjct: 422 EGSKAIEAALAAMTDIAKHIN 442
>UniRef50_Q96N96 Cluster: Spermatogenesis-associated protein 13;
n=29; Euteleostomi|Rep: Spermatogenesis-associated
protein 13 - Homo sapiens (Human)
Length = 652
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/140 (32%), Positives = 72/140 (51%), Gaps = 13/140 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPE----DVGHCFVTWAREFDMYVSYCRNKPDS-- 202
IFGNIE+I++F +R FL++L+K E ++G CF+ F +Y YC N P +
Sbjct: 285 IFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACL 343
Query: 203 NAAVVQHAGDY---FERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
A + G Y FE + ++ ++ + +L+ PVQ+I KY L L +L + G+
Sbjct: 344 ELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 403
Query: 371 ---IKDGLEVMLSVPKKAND 421
IK E M +V N+
Sbjct: 404 YSNIKAAYEAMKNVACLINE 423
>UniRef50_UPI00015B4CDD Cluster: PREDICTED: similar to pleckstrin
homology domain containing, family G (with RhoGef
domain) member 1; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to pleckstrin homology domain
containing, family G (with RhoGef domain) member 1 -
Nasonia vitripennis
Length = 1440
Score = 61.7 bits (143), Expect = 1e-08
Identities = 39/105 (37%), Positives = 59/105 (56%), Gaps = 5/105 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
+F NIE+I F+ R FL LD P V + F+ F +Y YC N P + + + +
Sbjct: 279 LFSNIEDIFEFN-RNFLSALDSSGLDPIAVANTFIEHNSGFKVYTEYCTNYPTTVSILTE 337
Query: 221 -HAGDYFERVQRKKK--LEH--PLAAYLIKPVQRITKYQLLLKDL 340
+ + R R+++ L H PL ++L+KPVQRI KY LLL++L
Sbjct: 338 LMSQEVIARAFRERQAALGHLLPLGSFLLKPVQRILKYHLLLENL 382
>UniRef50_O96035 Cluster: PEM-2; n=1; Ciona savignyi|Rep: PEM-2 -
Ciona savignyi (Pacific transparent sea squirt)
Length = 820
Score = 61.3 bits (142), Expect = 2e-08
Identities = 44/140 (31%), Positives = 70/140 (50%), Gaps = 13/140 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLREL----DKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
+FGNIE+I+ F +R F EL D T ++G+ F+ F +Y YC N P + A
Sbjct: 440 LFGNIEDIYLF-QREFAAELEASLDNVSTHATNIGNVFLKHKDGFCIYSEYCNNHPQAVA 498
Query: 209 AVVQHAGD-----YFERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
+ Q + +FE + ++ ++ PL +L+ PVQ+I KY L L +L G +
Sbjct: 499 ELAQLLTNKKFMHFFEACRLLQRMIDIPLDGFLLTPVQKICKYPLQLAELLKYTHPGHQD 558
Query: 371 ---IKDGLEVMLSVPKKAND 421
+K LE M V + N+
Sbjct: 559 YEAVKSALEAMKGVARMINE 578
>UniRef50_UPI000155FBE9 Cluster: PREDICTED: hypothetical protein; n=2;
Laurasiatheria|Rep: PREDICTED: hypothetical protein -
Equus caballus
Length = 1407
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 13/140 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPE----DVGHCFVTWAREFDMYVSYCRNKPDSNA 208
IFGNIE+I++F +R FL++L+K E ++G CF+ F +Y YC N P + A
Sbjct: 1040 IFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQHQEGFAIYSEYCNNHPGACA 1098
Query: 209 AV--VQHAGDY---FERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
+ + G Y FE + ++ ++ + +L+ PVQ+I KY L L +L + +
Sbjct: 1099 ELSSLMKQGRYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHSD 1158
Query: 371 ---IKDGLEVMLSVPKKAND 421
IK E M +V N+
Sbjct: 1159 YNNIKAAYEAMKNVACLINE 1178
>UniRef50_UPI0000D575D3 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor 4 isoform b; n=2;
Endopterygota|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor 4 isoform b - Tribolium
castaneum
Length = 1627
Score = 60.1 bits (139), Expect = 4e-08
Identities = 47/140 (33%), Positives = 69/140 (49%), Gaps = 13/140 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK---YETMPED-VGHCFVTWAREFDMYVSYCRNKPDSNA 208
IF N+E+I F F+++L+ +E + VG CF+ F MY YC + P + A
Sbjct: 1271 IFINLEDILHFQAN-FVKDLEAQIDFEAPYKSCVGGCFLKHRAGFKMYSEYCNSHPTATA 1329
Query: 209 AVVQ-----HAGDYFERVQRKKKL-EHPLAAYLIKPVQRITKYQLLLKDLQACCA---EG 361
A+ + H +FE + + L E PL YL+ PVQRI KY L L +L +
Sbjct: 1330 ALQELYQYNHYSKFFEACRLMRGLIEIPLDGYLLTPVQRICKYPLQLAELLKYTRPDHKD 1389
Query: 362 QGEIKDGLEVMLSVPKKAND 421
EIK+ L+ M V N+
Sbjct: 1390 YDEIKEALDAMRGVAVLINE 1409
>UniRef50_Q4SQR9 Cluster: Chromosome undetermined SCAF14531, whole
genome shotgun sequence; n=3; Clupeocephala|Rep:
Chromosome undetermined SCAF14531, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 954
Score = 60.1 bits (139), Expect = 4e-08
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 5/209 (2%)
Frame = +2
Query: 2 ASVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSY 181
+ P ++GK D +F + FH L ++ CF + +F Y Y
Sbjct: 591 SDTPASIRGKADALFPTWTSLSSFHSHNLLPAMEGALVQSLLQQDCFSKYRDQFLQYSHY 650
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAY-----LIKPVQRITKYQLLLKDLQA 346
R KPD ++ +V A D+F + K L PL+ L PVQR+ +Y L++L
Sbjct: 651 IRTKPDLDSPLVTQAADFF---KGKLPLASPLSPLSFPHCLGAPVQRLEQYCEALEELGG 707
Query: 347 CCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDH 526
L ++ + D L+ GC +P G++V QG L+ G
Sbjct: 708 I----NPACDSALSILRHAQRHGEDLRASDLILGCPIPVAERGDLVRQGELTVCGGPRRK 763
Query: 527 QKGTREESLLFDLHLAFWRKK*RIPTGKT 613
+ G R L+ L F + K P G+T
Sbjct: 764 RAGVR-NVFLYQHVLIFTKLKSPSP-GRT 790
>UniRef50_Q5ZLR6 Cluster: Rho guanine nucleotide exchange factor 6;
n=19; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 6 - Gallus gallus (Chicken)
Length = 764
Score = 60.1 bits (139), Expect = 4e-08
Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 7/138 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERV--FLRELDKYETMPEDVGHCFVTWAREF-DMYVSYCRNKPDSNAA 211
+ GN+EEI F + + L ++ K + VG CF+ +F +Y++YC N P + +
Sbjct: 277 LLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSV 336
Query: 212 VVQHAGDYFERVQRKKKLEHP----LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKD 379
+ QH+ D E+ + +P L L KP R+ KY LL++L+ E + +D
Sbjct: 337 LTQHS-DELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHED 395
Query: 380 GLEVMLSVPKKANDAMHL 433
L+ + S + L
Sbjct: 396 VLKAITSFKSLVSQCQEL 413
>UniRef50_Q17KZ4 Cluster: Putative uncharacterized protein; n=2;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 741
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 16/125 (12%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAR--EFDMYVS 178
++P L+G+ + +FGN+EEIH H+ FL L + E + CF+ + +F YV
Sbjct: 187 NLPGGLRGQRNNLFGNVEEIHELHQDDFLPALRRCYQNVEKIAQCFIHYVETGKFYCYVK 246
Query: 179 YCRNKPDSNAAVVQHAGDYFERVQRKKKL--------------EHPLAAYLIKPVQRITK 316
Y N+ S+ +H DYF ++ + +H L ++L++P+QR+ +
Sbjct: 247 YALNRRKSDTIFERHR-DYFSVIKLLHQTSCHQIMEFIILQSNQHELNSFLLQPIQRLPR 305
Query: 317 YQLLL 331
Y+L L
Sbjct: 306 YKLFL 310
>UniRef50_UPI0000F3273F Cluster: pleckstrin homology domain
containing, family G (with RhoGef domain) member 3; n=2;
Tetrapoda|Rep: pleckstrin homology domain containing,
family G (with RhoGef domain) member 3 - Bos Taurus
Length = 892
Score = 59.3 bits (137), Expect = 7e-08
Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 5/86 (5%)
Frame = +2
Query: 152 AREFDMYVSYCRNKPDSNAAVVQHAGD-----YFERVQRKKKLEHPLAAYLIKPVQRITK 316
++EFD+Y YC N P+S AA+ + D +F Q + PL +YL+KPVQRI K
Sbjct: 118 SQEFDIYTQYCNNYPNSVAALTECMQDKQQAKFFRDQQDLLQHSLPLGSYLLKPVQRILK 177
Query: 317 YQLLLKDLQACCAEGQGEIKDGLEVM 394
Y LLL+++ A+ E +DG EV+
Sbjct: 178 YHLLLQEI----AKHFDEEEDGFEVV 199
>UniRef50_P40995 Cluster: Rho guanine nucleotide exchange factor
scd1; n=1; Schizosaccharomyces pombe|Rep: Rho guanine
nucleotide exchange factor scd1 - Schizosaccharomyces
pombe (Fission yeast)
Length = 872
Score = 59.3 bits (137), Expect = 7e-08
Identities = 40/137 (29%), Positives = 66/137 (48%), Gaps = 6/137 (4%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED---VGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF N+ EI F R FL L+ ++P + +G F+ F +Y +C N P++
Sbjct: 271 IFTNLNEILDFQRR-FLVGLEMNLSLPVEEQRLGALFIALEEGFSVYQVFCTNFPNAQQL 329
Query: 212 VVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG---QGEIKDG 382
++ + +V + + L A LIKP+QRI KY LLL L G + E+K G
Sbjct: 330 IIDNQNQLL-KVANLLEPSYELPALLIKPIQRICKYPLLLNQLLKGTPSGYQYEEELKQG 388
Query: 383 LEVMLSVPKKANDAMHL 433
+ ++ V + N+ +
Sbjct: 389 MACVVRVANQVNETRRI 405
>UniRef50_Q4SFB4 Cluster: Chromosome 6 SCAF14605, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 6 SCAF14605, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1667
Score = 58.8 bits (136), Expect = 1e-07
Identities = 58/216 (26%), Positives = 99/216 (45%), Gaps = 30/216 (13%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPE-----DVGHCFVTWAREFDMYVSYCRNKPDS 202
++F NIEEI H R FL +D PE ++G CF+ + F +Y YC N +
Sbjct: 51 VLFSNIEEILAVH-RDFLSMVDDL-LQPEPHAHHEIGRCFLHFRSRFQVYDEYCGNHEKA 108
Query: 203 NAAVVQHAGDYFER--------VQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAE 358
+++ R + +K E PL YL+ P+QRI KY LLL++L
Sbjct: 109 QRLLLELNKIRSVRTCLLNCMLLGGRKNTEVPLEGYLVAPIQRICKYPLLLRELLKRTPR 168
Query: 359 GQGE---IKDGLEVMLSVPKKANDA--------------MHLSLLEGCDVPTDSLGEVVL 487
+ +++ L++M +V N+A H+ EG ++ TD+ E+++
Sbjct: 169 KHSDYVLVQESLQMMKAVCSSINEAKRQMEKLEILEEWQSHIEGWEGSNI-TDTCTELLM 227
Query: 488 QGLLSRVGPSSDHQKGTREESLLFDLHLAFWRKK*R 595
G+L ++ + ++ LFD L + +KK R
Sbjct: 228 HGVLLKISAGNIQER----IFFLFDKLLVYCKKKNR 259
>UniRef50_Q4SIP5 Cluster: Chromosome 21 SCAF14577, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 21 SCAF14577, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1228
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/60 (46%), Positives = 39/60 (65%)
Frame = +2
Query: 155 REFDMYVSYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLK 334
R +MYV YC+NKP S V ++ YFE ++++ + ++ L KPVQRI KYQLLLK
Sbjct: 219 RRLNMYVLYCQNKPKSEHIVSEYIDTYFEDLRQQLGHKLQISDLLFKPVQRIMKYQLLLK 278
>UniRef50_A4R6Z2 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1127
Score = 58.4 bits (135), Expect = 1e-07
Identities = 51/150 (34%), Positives = 79/150 (52%), Gaps = 15/150 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV---GHCFVTWAREFD-MYVSYCRNKPDSNA 208
IFGNI+ I F R FL ++ +MP +V G FV FD +Y + N+ A
Sbjct: 361 IFGNIDAILDFQRR-FLIRVETTNSMPGEVQQWGSPFVAMEASFDPIYTPFIANQ--RKA 417
Query: 209 AVVQHAGDYFERVQRKKKLEHPLAA-------YLIKPVQRITKYQLLLKDLQACCAEGQG 367
A++ A F+++ K +EHP+A +L+KP+QR+ KY LLLKDL
Sbjct: 418 ALI--AQSEFDKI---KSIEHPVACDFNTLDGFLLKPMQRLVKYPLLLKDLLK--KSEDD 470
Query: 368 EIKDGLEVMLSVP----KKANDAMHLSLLE 445
++KD L + ++ +KAN+A+ LL+
Sbjct: 471 KVKDDLSLGIAAAERTLQKANEAVDRDLLD 500
>UniRef50_UPI000069EC71 Cluster: CDNA FLJ43173 fis, clone
FCBBF3007540, weakly similar to GUANINE NUCLEOTIDE
EXCHANGE FACTOR DBS.; n=1; Xenopus tropicalis|Rep: CDNA
FLJ43173 fis, clone FCBBF3007540, weakly similar to
GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS. - Xenopus
tropicalis
Length = 286
Score = 56.4 bits (130), Expect = 5e-07
Identities = 43/167 (25%), Positives = 83/167 (49%), Gaps = 5/167 (2%)
Frame = +2
Query: 47 GNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHA 226
G+IE++ FH R FLR+L + P V +CF+ R F M+V +K A++ H
Sbjct: 33 GSIEQLLNFHTR-FLRDLQNCVSQPLTVSYCFLQHVRYFLMFV-VATHKKIQIFAILYH- 89
Query: 227 GDYFERVQRK-KKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQGE---IKDGLEV 391
YF++ +R+ +K E L +P++++ +YQ L D +Q C E + E + E+
Sbjct: 90 --YFQQGRRRDQKEEDDSRIILQRPLEQLDQYQRFLGDMMQECDQENEQERQSLHTAREL 147
Query: 392 MLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSSDHQK 532
+ S+ + + + + G +V G ++L+ + + + Q+
Sbjct: 148 VSSLVPYGKNLLAVEAIRGFEVDEKEHGRLLLKDVFTVISGRKKSQR 194
>UniRef50_Q9XXM9 Cluster: Putative uncharacterized protein uig-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein uig-1 - Caenorhabditis elegans
Length = 919
Score = 56.0 bits (129), Expect = 7e-07
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 10/137 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN--KPDSNAAV 214
+FG IE I F+++++ +LD + + CFV + +F+ Y+ YC N + S
Sbjct: 270 LFGCIERIFAFNKQLY-NQLDAADLDCVKMSRCFVESSGKFEDYIEYCTNYHRMMSTLYH 328
Query: 215 VQHAGDYFERVQ-RKKKLEHPL--AAYLIKPVQRITKYQLLLKDL-----QACCAEGQGE 370
+Q +Q R+ L H L +AYL+KPVQRI KY L L+++ E +
Sbjct: 329 LQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELIQ 388
Query: 371 IKDGLEVMLSVPKKAND 421
+K EVM S + ND
Sbjct: 389 VKRAHEVMTSQAARIND 405
>UniRef50_Q4PBU1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1102
Score = 55.2 bits (127), Expect = 1e-06
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 12/143 (8%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED--VGHCFVTWAREFDMYVSYCRNKPDSNAAV 214
+FGN+ ++ R + + P++ GH F+T +F +Y +C N + +
Sbjct: 316 LFGNLNKLVDVQRRFLICVEENVRRTPDEQHFGHVFMTMEEDFSVYEPFCANYNLALDLI 375
Query: 215 VQHAGDYFERVQRKKKLE-------HPLAAYLIKPVQRITKYQLLLKDL---QACCAEGQ 364
Q A + R++ E + L ++IKPVQRI KY LLL+ L + A
Sbjct: 376 NQEAHNLI-RLKGMPSAEGCYLDPAYELPTFMIKPVQRICKYPLLLEQLLKKTSDDAPRY 434
Query: 365 GEIKDGLEVMLSVPKKANDAMHL 433
E+++GLEVM + K N+ L
Sbjct: 435 QELQNGLEVMRRITDKVNETSRL 457
>UniRef50_Q4RY71 Cluster: Chromosome 3 SCAF14978, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14978, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 504
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/107 (31%), Positives = 58/107 (54%), Gaps = 7/107 (6%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED---VGHCFVTWAREF-DMYVSYCRNKPDSNA 208
I GN+EEI F +++ ++ L+++ +PE+ +G F++ + MYV+YC N P + +
Sbjct: 76 ILGNLEEISTF-QQMLVQSLEEHTKLPENQQRIGGFFLSLMPQMKSMYVAYCSNHPSAVS 134
Query: 209 AVVQHA---GDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ QH+ G+Y E L L KP R+ +Y LLK+L
Sbjct: 135 VLTQHSQELGEYMESKGASSPGILILTTSLSKPFTRLERYPALLKEL 181
>UniRef50_UPI0000F21464 Cluster: PREDICTED: hypothetical protein; n=4;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1223
Score = 54.0 bits (124), Expect = 3e-06
Identities = 36/111 (32%), Positives = 62/111 (55%), Gaps = 11/111 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPE-----DVGHCFVTWAREFDMYVSYCRNKPDSN 205
IF NIE+I+RF +R FL++L++ + PE ++G CF+ F +Y YC P +
Sbjct: 854 IFSNIEDIYRF-QRKFLKDLER-KYNPENPHLSEIGSCFLQQEEGFSIYSEYCNTHPVAC 911
Query: 206 AAVVQ-----HAGDYFERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
A + + +FE + ++ ++ +A +L+ PVQ+I KY L L +L
Sbjct: 912 AELQRLMKQSRYKHFFEACRLLQQMIDISIAGFLLTPVQKICKYPLQLGEL 962
>UniRef50_UPI0000E463E9 Cluster: PREDICTED: similar to Cdc42 guanine
nucleotide exchange factor (GEF) 9; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Cdc42 guanine nucleotide exchange factor (GEF) 9 -
Strongylocentrotus purpuratus
Length = 1951
Score = 54.0 bits (124), Expect = 3e-06
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 13/140 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKY--ETMPE--DVGHCFVTWAREFDMYVSYCRNKPDSNA 208
+F NIEEI+ F +R FL +L+ + MP +G CF+ + FD+Y YC N P +
Sbjct: 1621 LFCNIEEIYCFQQR-FLADLETCIDKEMPNLSAIGDCFLKYKSTFDIYGEYCNNYPHAMN 1679
Query: 209 AVVQHAGD-----YFERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
D +FE + + ++ L +L+ PVQ+I KY L L +L +
Sbjct: 1680 EFQTLMRDNKYVQFFEACRLLQSMIKIQLDGFLLTPVQKICKYPLQLNELLKYTRPQHPD 1739
Query: 371 ---IKDGLEVMLSVPKKAND 421
+K LE M V + N+
Sbjct: 1740 YQPLKSALEAMREVAQSINE 1759
>UniRef50_UPI0000DA28FB Cluster: PREDICTED: similar to DEP domain
containing 2 isoform a; n=1; Rattus norvegicus|Rep:
PREDICTED: similar to DEP domain containing 2 isoform a
- Rattus norvegicus
Length = 1599
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/144 (27%), Positives = 69/144 (47%), Gaps = 15/144 (10%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKY----ETMPEDVGHCFVTWAREFDMYVSYCRNKPDSN 205
++F NIEEI H+ FL+ +++ ++VG CF+ + +F +Y YC N +
Sbjct: 64 MLFSNIEEILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLNFKDKFRIYDEYCSNHEKAQ 122
Query: 206 AAVVQHAGDYFER--------VQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
+++ R + +K + PL YL+ P+QRI KY LLLK+L
Sbjct: 123 KLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRK 182
Query: 362 QGE---IKDGLEVMLSVPKKANDA 424
+ + + L+ M +V N+A
Sbjct: 183 HSDYTAVMEALQAMKAVCSNINEA 206
>UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio
"Obscurin-MLCK.; n=1; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Obscurin-MLCK. - Takifugu rubripes
Length = 1948
Score = 53.6 bits (123), Expect = 4e-06
Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 4/134 (2%)
Frame = +2
Query: 113 TMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHA-GDYFERVQRKKKLEHPLAAYL 289
T +DV ++ A F+ Y+ Y + + A + A YF+ + + ++
Sbjct: 2 TTDDDVAMLLISHAENFEKYLHYMVGQAQAEACIADKAVQQYFKVMCLPTSPAMDVLTFI 61
Query: 290 IKPVQRITKYQLLLKDLQACCAE-GQG--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVP 460
+PV+RI YQ LLK+L A+ GQ ++ ++ S+P ++++ +SL+E P
Sbjct: 62 QQPVERIQTYQALLKELIKNKAKSGQSCCLLEKSFSMVSSLPWRSDNLHQVSLIENYPAP 121
Query: 461 TDSLGEVVLQGLLS 502
+LGE V QG+ +
Sbjct: 122 LTALGEPVRQGVFT 135
>UniRef50_Q9NR80 Cluster: Rho guanine nucleotide exchange factor 4;
n=65; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 4 - Homo sapiens (Human)
Length = 657
Score = 53.2 bits (122), Expect = 5e-06
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 13/140 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKY--ETMPE--DVGHCFVTWAREFDMYVSYCRNKPD--- 199
IFGNIE+I+R ++ F++ L++ P ++G CF+ +F +Y YC N P+
Sbjct: 296 IFGNIEDIYRC-QKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACV 354
Query: 200 --SNAAVVQHAGDYFERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
S + +FE + +K ++ L +L+ PVQ+I KY L L +L +
Sbjct: 355 ELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRD 414
Query: 371 IKD---GLEVMLSVPKKAND 421
KD L M +V + N+
Sbjct: 415 FKDVEAALHAMKNVAQLINE 434
>UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor 6;
n=14; Tetrapoda|Rep: Rho guanine nucleotide exchange
factor 6 - Homo sapiens (Human)
Length = 776
Score = 52.8 bits (121), Expect = 6e-06
Identities = 35/127 (27%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREF-DMYVSYCRNKPDSNAA 211
+ GN EE+ F + + L E K+ VG C ++ F MY++YC N P +
Sbjct: 285 LLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNV 344
Query: 212 VVQHAGDYFERVQRKKKLEHP----LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKD 379
+ QH+ D E+ + P L L KP R+ KY LL++L+ + + +D
Sbjct: 345 LTQHS-DELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQD 403
Query: 380 GLEVMLS 400
L+ +++
Sbjct: 404 ILKAIVA 410
>UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome shotgun
sequence; n=4; Tetraodontidae|Rep: Chromosome 1
SCAF14995, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 5505
Score = 52.4 bits (120), Expect = 8e-06
Identities = 48/170 (28%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Frame = +2
Query: 32 EDLI-FGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
EDL G+ E +R R + L + T +DV F+T F+ Y+ Y + + A
Sbjct: 4080 EDLDGIGSTGEEYRRSLRSIIPGLRECAT-DDDVAMLFITHTDSFEKYLHYMEGQAQAEA 4138
Query: 209 AVVQHAGDYFERVQ----RKKKLEHPLAA-----YLIKPVQRITKYQLLLKDLQACCAE- 358
+ A F +V R+ AA ++ +PV+RI YQ LLK+L A+
Sbjct: 4139 CITDKAIQQFFKVTNLTTRESAASLEAAAMDVLTFIQQPVERIQTYQALLKELIKNKAKS 4198
Query: 359 GQG--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLS 502
GQ +++ ++ S+P ++++ +SL+E P +LGE V QG+ +
Sbjct: 4199 GQSCCLLENSFSLVSSLPWRSDNLHQVSLIENYPAPLTALGEPVRQGIFT 4248
>UniRef50_A7RTF1 Cluster: Predicted protein; n=8; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 430
Score = 52.4 bits (120), Expect = 8e-06
Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKY-ETMPED--VGHCFVTWAREFDMYVSYCRNKPDSNA 208
L+F NIE+I+ FH+++ L+ D Y + P D +G F+ F +Y YC N P + A
Sbjct: 136 LLFSNIEQIYEFHQKLLLQLEDCYLKDNPCDSMIGRVFLENKEGFQIYSEYCNNHPHAIA 195
Query: 209 AV--VQHAGDY---FERVQ-RKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ + + +Y FE + + + L +L+ PVQ+I KY L L +L
Sbjct: 196 ELKTLCESNNYKHFFEACRLLQDMINISLDGFLLTPVQKICKYPLQLAEL 245
>UniRef50_Q70Z35 Cluster: DEP domain-containing protein 2
(Phosphatidylinositol 3,4,5- trisphosphate-dependent Rac
exchanger 2) (PtdIns(3,4,5)-dependent Rac exchanger 2);
n=33; Euteleostomi|Rep: DEP domain-containing protein 2
(Phosphatidylinositol 3,4,5- trisphosphate-dependent Rac
exchanger 2) (PtdIns(3,4,5)-dependent Rac exchanger 2) -
Homo sapiens (Human)
Length = 1606
Score = 52.4 bits (120), Expect = 8e-06
Identities = 52/215 (24%), Positives = 99/215 (46%), Gaps = 29/215 (13%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKY----ETMPEDVGHCFVTWAREFDMYVSYCRNKPDSN 205
++F NIE+I H+ FL+ +++ ++VG CF+ + +F +Y YC N +
Sbjct: 72 MLFSNIEDILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQ 130
Query: 206 AAVVQHAGDYFER--------VQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
+++ R + +K + PL YL+ P+QRI KY L+LK+L
Sbjct: 131 KLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRK 190
Query: 362 QGE---IKDGLEVMLSVPKKANDA--------------MHLSLLEGCDVPTDSLGEVVLQ 490
+ + + L+ M +V N+A H+ EG ++ TD+ E+++
Sbjct: 191 HSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNI-TDTCTEMLMC 249
Query: 491 GLLSRVGPSSDHQKGTREESLLFDLHLAFWRKK*R 595
G+L ++ + ++ LFD L + ++K R
Sbjct: 250 GVLLKISSGNIQER----VFFLFDNLLVYCKRKHR 280
>UniRef50_Q7S4Y3 Cluster: Putative uncharacterized protein
NCU06067.1; n=2; Sordariomycetes|Rep: Putative
uncharacterized protein NCU06067.1 - Neurospora crassa
Length = 970
Score = 52.0 bits (119), Expect = 1e-05
Identities = 46/147 (31%), Positives = 74/147 (50%), Gaps = 12/147 (8%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPE---DVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF NI I H+R FL ++ +MP+ + G FVT F +Y + N+ +
Sbjct: 253 IFLNINAILD-HQRKFLIRVETTNSMPQARQEWGSLFVTAEENFGIYQPFIANQRKA--- 308
Query: 212 VVQHAGDYFERVQRKKKLEHPLAA-------YLIKPVQRITKYQLLLKDL--QACCAEGQ 364
Q A F+++Q + HP+A +L+KP+QR+ KY LLLKDL ++ +
Sbjct: 309 -AQVATQVFDKIQ---EAGHPVACDFNTLDGFLLKPMQRLVKYPLLLKDLLKKSEDEHTK 364
Query: 365 GEIKDGLEVMLSVPKKANDAMHLSLLE 445
++ G+ V KAN A+ ++LE
Sbjct: 365 EDLAAGIAAAERVLMKANSAVDKNILE 391
>UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep:
LOC572412 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1095
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/173 (26%), Positives = 84/173 (48%), Gaps = 12/173 (6%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN 190
P + +++ IF NI ++ FH + L +L +T +D+ F+ + F+ Y+ Y
Sbjct: 246 PPEITMQKETIFRNINDLKAFHSSL-LPDLRDCDT-DDDIAMHFLKNSEGFEKYLQYLIG 303
Query: 191 KPD-----SNAAVVQHAGDY-FERVQRKKKLEHPLA---AYLIKPVQRITKYQLLLKDL- 340
+ S V Q+ DY + E P+ AYL +P +RI KY+ LLK+L
Sbjct: 304 QLQAESIISEKQVHQYFKDYSVSELANVDPSEGPVLSINAYLQRPPERIQKYRALLKELI 363
Query: 341 QACCAEGQG--EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQG 493
+ GQ ++ ++ S+ +++ + H+SL+E ++LGE + QG
Sbjct: 364 RNKARNGQNCCLLEQAYAMVSSLSQRSENTHHVSLIENYPANLEALGEPIRQG 416
>UniRef50_Q4RP06 Cluster: Chromosome 10 SCAF15009, whole genome
shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 10
SCAF15009, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2108
Score = 51.2 bits (117), Expect = 2e-05
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 24/157 (15%)
Frame = +2
Query: 23 QGKEDLIFGNIEEIHRFHERVFLRELD-KYETMPE---------------DVGHCFVTWA 154
Q + + +FG++ E+ F +RVFL+ L+ K + P+ +G F+ +A
Sbjct: 1538 QDEMESLFGSLPEMLDF-QRVFLQTLEEKIASSPDCSTLETPAQFKKLLFSLGGSFLYYA 1596
Query: 155 REFDMYVSYCRN-----KPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKY 319
F +Y +C N K A Q ++ E K+ L +YLIKPVQR+ KY
Sbjct: 1597 DHFKLYSGFCANHIKVQKVLERAKTDQAFKEFLEARNLTKQHSSTLESYLIKPVQRVLKY 1656
Query: 320 QLLLKDLQA---CCAEGQGEIKDGLEVMLSVPKKAND 421
LLL++L + C +E + + L+ M V N+
Sbjct: 1657 PLLLRELVSLTDCDSEEHYHLTEALKAMEKVASHINE 1693
>UniRef50_UPI000049A257 Cluster: Rho guanine nucleotide exchange
factor; n=3; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 489
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 10/120 (8%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYVSYC 184
PL + LIFG + I+ + + LRE T G +T+ +Y YC
Sbjct: 155 PLLTPEQMKLIFGGVSVIYGVNTALLENLREKLSVYTQNSRFGRIVLTFTPLLRVYSDYC 214
Query: 185 RNKPDSNAAV----VQHAGDYFERVQRKKKLEH----PLAAYLIKPVQRITKYQLLLKDL 340
+ P N V V H F ++Q K+ EH L + LI P+QR+ +Y+LLLKDL
Sbjct: 215 QIYPQINQLVSSMKVPHPFGTFYKLQMKQAPEHLQGFDLLSLLITPIQRLPRYRLLLKDL 274
>UniRef50_Q17KZ0 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 956
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAR--EFDMYVSYC 184
P+ L+ + +FGNIE IH+FH+ +FL +L + + F + F YV Y
Sbjct: 280 PIELKNMKYHLFGNIEFIHKFHKTIFLPKLMACGKDVQKLAKVFCQYLENDSFYGYVLYA 339
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
S Q A +FE Q + + +++++P+QR+ +Y++LL+++ +
Sbjct: 340 LYNTKSQRLCEQLA-KFFESQQNCSGDKLGVKSFILQPIQRLPRYKILLENIAKALRSSE 398
Query: 365 GEIKDGLEVMLSVPKKANDAM 427
D L+ A M
Sbjct: 399 SVSGDESSTQLNAVLGAKQMM 419
>UniRef50_A0FEW6 Cluster: Cdc24; n=2; Filobasidiella neoformans|Rep:
Cdc24 - Cryptococcus neoformans var. grubii
(Filobasidiella neoformans var.grubii)
Length = 1112
Score = 50.8 bits (116), Expect = 3e-05
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV---------GHCFVTWAREFDMYVSYCRNK 193
IF N+ +I FH + ++ +YE + E G F+ EFD Y YC N
Sbjct: 345 IFSNLSKILDFHRKFLIKLETEYEPIQERGPGAWAEGVWGRPFILSEAEFDCYGPYCANY 404
Query: 194 PDSNAAVVQHAGDYFERVQRKKKLEHP-------LAAYLIKPVQRITKYQLLLKDLQACC 352
D+ VV R Q E P L A++IKP+QRITKY LLL +
Sbjct: 405 LDA-ITVVNEQMPILMRGQELSPGERPCLDPQRELQAFMIKPIQRITKYGLLLDAILHAT 463
Query: 353 AEGQGEIKDGLEVMLSVPKK 412
A+ + + LE + K+
Sbjct: 464 AKHEYPFRPELEEASAAVKR 483
>UniRef50_Q960B3 Cluster: SD09786p; n=4; Sophophora|Rep: SD09786p -
Drosophila melanogaster (Fruit fly)
Length = 592
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/110 (30%), Positives = 60/110 (54%), Gaps = 2/110 (1%)
Frame = +2
Query: 8 VPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWARE--FDMYVSY 181
+PL L+GK+ +FGNIE+I FH FL L + + + F+ + + F YV +
Sbjct: 267 LPLGLRGKKYDLFGNIEQIAEFHRDEFLPMLQRNRRDLKRLFDEFLQFLDQHCFYGYVIF 326
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLL 331
NK S + +YF ++ ++ + + ++L++P+QR+ +Y LLL
Sbjct: 327 TMNKQKS-LKLCDLYKNYFTSIRLERDDKLGINSFLVQPIQRMARYPLLL 375
>UniRef50_A7RK39 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 265
Score = 50.4 bits (115), Expect = 3e-05
Identities = 59/219 (26%), Positives = 98/219 (44%), Gaps = 26/219 (11%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYE---TMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF NI IH+FH L +L++ T +G T A MY +Y N +N
Sbjct: 5 IFANIGSIHKFHSDFLLPKLEERMAQWTTNNTLGDILKTLAPFLKMYSAYVGNFDKANET 64
Query: 212 V------VQHAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
V + +QR + E+ L ++++P+QR+ +Y+LLL D E +
Sbjct: 65 VSVWLKKLPKFASVINEIQRSPESENLTLQHHMLEPIQRVPRYKLLLTDYINKLPEDSPD 124
Query: 371 I---KDGLEVMLSVPKKANDAMHLS------------LLEGCDVPTDSLGEVVLQGLLSR 505
+ KD L ++ +++N+ M + LLE D+ T S E V +G++ +
Sbjct: 125 VNATKDALAIVSKAAQQSNEIMKKTERFQKLLEIQERLLEQSDIITPS-REFVKEGVIRK 183
Query: 506 VGPSSDHQKGTREESL-LFDLHLAFWRKK*RIPTGKTQI 619
V S+ G ++ L LF+ L K PTGK ++
Sbjct: 184 V--SARKHVGQQDRYLILFNDKLLCCSK---FPTGKLKM 217
>UniRef50_Q6CBW7 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome C of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 769
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
L+F N+ + F RV + + + G F+ F +Y Y N+ S+
Sbjct: 310 LMFLNVSALVDFQRRVLVGIEHVCSLPVEEQRFGALFLNMEAGFHIYEPYALNQKASSDL 369
Query: 212 VVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQ---GEIKDG 382
VQ A + + + L A+LIKP+QRI KY LLL++L + E+ DG
Sbjct: 370 AVQEAPK-LTALAHIIEPTYELQAFLIKPIQRICKYPLLLRELVKVSSSDHPYASELLDG 428
Query: 383 LEVMLSVPKKAND 421
LE + V N+
Sbjct: 429 LEAIKRVTNSVNE 441
>UniRef50_Q14155 Cluster: Rho guanine nucleotide exchange factor 7;
n=50; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 7 - Homo sapiens (Human)
Length = 803
Score = 50.4 bits (115), Expect = 3e-05
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 6/107 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFD-MYVSYCRNKPDSNAA 211
+ GN+EEI F + + L E K + VG CF+ + +Y++YC N P +
Sbjct: 315 LMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNV 374
Query: 212 VVQHA---GDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQ 343
+ +H+ G++ E L L KP R+ KY LLK+L+
Sbjct: 375 LTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELE 421
>UniRef50_Q13009 Cluster: T-lymphoma invasion and metastasis-inducing
protein 1; n=31; Euteleostomi|Rep: T-lymphoma invasion
and metastasis-inducing protein 1 - Homo sapiens (Human)
Length = 1591
Score = 50.0 bits (114), Expect = 5e-05
Identities = 33/124 (26%), Positives = 64/124 (51%), Gaps = 5/124 (4%)
Frame = +2
Query: 89 LRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHAGD-----YFERVQR 253
L ++D+++ + +G F+ +A F +Y ++C + +V+ D + +
Sbjct: 1115 LEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNP 1174
Query: 254 KKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKANDAMHL 433
K++ L +YLIKP+QRI KY LLL++L A + + E L+V + K A H+
Sbjct: 1175 KQQHSSTLESYLIKPIQRILKYPLLLRELFA-LTDAESEEHYHLDVAIKTMNKV--ASHI 1231
Query: 434 SLLE 445
+ ++
Sbjct: 1232 NEMQ 1235
>UniRef50_UPI0001555B97 Cluster: PREDICTED: similar to FLJ00056
protein, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to FLJ00056 protein, partial -
Ornithorhynchus anatinus
Length = 558
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/158 (21%), Positives = 68/158 (43%), Gaps = 4/158 (2%)
Frame = +2
Query: 29 KEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
K + + G E +HRFH FL EL P VG CF+ + +F +Y Y +++ +
Sbjct: 155 KWNALLGARERLHRFHRLHFLPELQGCAARPLRVGACFLRYGDQFSLYTQYMKHRHELET 214
Query: 209 AVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLE 388
+ + P L +P++++ Y LL++L +G + L
Sbjct: 215 RLAALSTPTKGSGPSGTSEGCPSPWPLQRPLEQLGHYGRLLRELLQEAGSERGPERQALA 274
Query: 389 VMLSV----PKKANDAMHLSLLEGCDVPTDSLGEVVLQ 490
L + ++ ++ + + + GC+V G ++L+
Sbjct: 275 AALQLLQDQEEEGHNLLAVEAVRGCEVDLKEQGPLLLR 312
>UniRef50_Q7Z628 Cluster: Neuroepithelial cell-transforming gene 1
protein; n=18; Euteleostomi|Rep: Neuroepithelial
cell-transforming gene 1 protein - Homo sapiens (Human)
Length = 596
Score = 49.6 bits (113), Expect = 6e-05
Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +2
Query: 14 LPLQGKEDL--IFGNIEEIHRFHERVFLR--ELDKYETMPEDVGHCFVTWAREFDMYVSY 181
L + +E+L IFG+++ HE + R E K + E +GH V+W + Y Y
Sbjct: 207 LSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGY 266
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHP------LAAYLIKPVQRITKYQLLLKDL 340
C N+ + A + Q D + ++ LE P L ++L P R+ KY LLLK++
Sbjct: 267 CSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEI 325
>UniRef50_UPI0000F1DCF3 Cluster: PREDICTED: hypothetical protein; n=1;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1384
Score = 49.2 bits (112), Expect = 8e-05
Identities = 40/103 (38%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +2
Query: 140 FVTWAREFDMYVSY----CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQR 307
+ T+ REFD V+ CR P ++ V Q FE R L L YL+KPVQR
Sbjct: 913 YSTYIREFDRNVALLDEQCRKNPPFSSVVRQ-----FETSPRCASLA--LKHYLLKPVQR 965
Query: 308 ITKYQLLLKDLQACCAEGQGEIKD---GLEVMLSVPKKANDAM 427
I +YQLLL D E + KD L V+ V AND M
Sbjct: 966 IPQYQLLLTDYLKNLPEDSSDYKDTQTALSVVKEVANHANDIM 1008
>UniRef50_UPI0000519B3F Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 4 isoform 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to FYVE, RhoGEF and PH
domain containing 4 isoform 1 - Apis mellifera
Length = 729
Score = 49.2 bits (112), Expect = 8e-05
Identities = 52/202 (25%), Positives = 90/202 (44%), Gaps = 25/202 (12%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK----YETMPE--DVGHCFVTWAREFDMYVS---YCRNK 193
+F NI+ I++FH L +L + +++ P D+ F + + + YV Y N
Sbjct: 229 MFSNIKSIYKFHNDFLLPQLQERMQNWDSNPRIGDIMKNFAPFLKMYTEYVKNFDYAMNL 288
Query: 194 PDSNAAVVQHAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
S V + +Q+ + L +++ P+QR+ +Y+LLLKD E +
Sbjct: 289 IQSLQTKVTRFAAIIDEIQKLDECAKLSLPHHMLSPIQRLPRYELLLKDYLKNLTEENAD 348
Query: 371 IKD---GLEVMLSVPKKANDAMH--------LSLLEGCDVPTDSLG---EVVLQGLLSRV 508
KD LE++ + NDAM L + E TD + E++ +G + ++
Sbjct: 349 YKDTKKALELVSTAANHTNDAMKKIDKFKKLLEIQESIYDTTDLVSATRELIKEGRIVKI 408
Query: 509 GP-SSDHQKGTREESLLFDLHL 571
S DHQ+ R+ L DL L
Sbjct: 409 SARSGDHQE--RQLFLFSDLLL 428
>UniRef50_UPI000049A4D9 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 730
Score = 49.2 bits (112), Expect = 8e-05
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 9/111 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFL--RELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
D+IF + +E+ ++ FL ++L + + +G F + F +Y Y + DSN
Sbjct: 50 DIIFEHYDEVLNINKNFFLALKKLQETHKIETHLGQIFKLFTPFFKVYFLYISHYDDSNQ 109
Query: 209 AVVQHAGD-YFERVQRKKKLEHP------LAAYLIKPVQRITKYQLLLKDL 340
+ ++ + F + + + P L +YLI PVQR+ +Y+LLLKDL
Sbjct: 110 VLTEYEKNPKFNELLASLQTQIPTTTNLDLRSYLIMPVQRLPRYELLLKDL 160
>UniRef50_Q5RH33 Cluster: Novel protein similar to human and mouse
FYVE, RhoGEF and PH domain containing 6; n=3; Danio
rerio|Rep: Novel protein similar to human and mouse FYVE,
RhoGEF and PH domain containing 6 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 1315
Score = 49.2 bits (112), Expect = 8e-05
Identities = 40/103 (38%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +2
Query: 140 FVTWAREFDMYVSY----CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQR 307
+ T+ REFD V+ CR P ++ V Q FE R L L YL+KPVQR
Sbjct: 864 YSTYIREFDRNVALLDEQCRKNPPFSSVVRQ-----FETSPRCASLA--LKHYLLKPVQR 916
Query: 308 ITKYQLLLKDLQACCAEGQGEIKD---GLEVMLSVPKKANDAM 427
I +YQLLL D E + KD L V+ V AND M
Sbjct: 917 IPQYQLLLTDYLKNLPEDSSDYKDTQTALSVVKEVANHANDIM 959
>UniRef50_Q16JM6 Cluster: Rho guanine exchange factor; n=2;
Culicidae|Rep: Rho guanine exchange factor - Aedes
aegypti (Yellowfever mosquito)
Length = 977
Score = 49.2 bits (112), Expect = 8e-05
Identities = 34/108 (31%), Positives = 57/108 (52%), Gaps = 6/108 (5%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDS---- 202
++IF N+E+I RF ++ FL L + +G F+ + F +Y +YC + P +
Sbjct: 486 NIIFSNLEKIWRF-QQTFLDAL-RIAVPANRIGEVFLEYQSAFMIYSAYCNSYPRALMEL 543
Query: 203 -NAAVVQHAGDYFERVQRKKKL-EHPLAAYLIKPVQRITKYQLLLKDL 340
N + A E + + L E PL+A+L+ P+QRI +Y L L +L
Sbjct: 544 ENYTNNKEACTILESCRVSQNLPELPLSAHLLAPIQRICRYPLHLSEL 591
>UniRef50_Q0UQ03 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1029
Score = 49.2 bits (112), Expect = 8e-05
Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV--GHCFVTWAREFDMYVSYCRNKPDSNAAV 214
IF N+ + F R +R PE+ G+ FV + F +Y Y N+
Sbjct: 312 IFLNLNALLDFQRRFLIRVEQTNAQPPEEQNWGNLFVLYKEAFKVYEPYIANQKKCEQIA 371
Query: 215 VQHAGDYFER---VQRKKKLEHP--LAAYLIKPVQRITKYQLLLKDL--QACCAEG-QGE 370
++ E + ++ +E P L ++L+KP QR+TKY LLL L + EG + +
Sbjct: 372 MREFEKLKETGGSPEMRQMVESPTLLTSFLLKPFQRLTKYPLLLSQLRDKGDLDEGRRDD 431
Query: 371 IKDGLEVMLSVPKKANDAM 427
I G+E SV NDA+
Sbjct: 432 ISRGIEAASSVLAGTNDAI 450
>UniRef50_Q8TCU6 Cluster: Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein;
n=33; Eukaryota|Rep: Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein -
Homo sapiens (Human)
Length = 1659
Score = 49.2 bits (112), Expect = 8e-05
Identities = 57/221 (25%), Positives = 99/221 (44%), Gaps = 30/221 (13%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPE-----DVGHCFVTWAREFDMYVSYCRNKPDS 202
++F NIE+I H+ FL L+ Y PE ++G+ F+ + +F +Y YC N +
Sbjct: 98 VLFSNIEDILEVHKD-FLAALE-YCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKA 155
Query: 203 NAAVVQHAGDYFER--------VQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAE 358
+V+ R + +K + PL YL+ P+QRI KY LLLK+L
Sbjct: 156 LRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPG 215
Query: 359 GQGE---IKDGLEVMLSVPKKANDA--------------MHLSLLEGCDVPTDSLGEVVL 487
+ ++ L+ M +V N+ H+ EG ++ TD +++L
Sbjct: 216 KHPDHPAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNL-TDICTQLLL 274
Query: 488 QGLLSRVGPSSDHQKGTREESLLFDLHLAFWRKK*RIPTGK 610
QG L ++ + ++ LFD L + ++K R+ K
Sbjct: 275 QGTLLKISAGNIQERA----FFLFDNLLVYCKRKSRVTGSK 311
>UniRef50_UPI0000F1FC93 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1585
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)
Frame = +2
Query: 77 ERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHAGD-----YFE 241
ERV L L+ + D+ + + FD+Y YC N P+S + + +F+
Sbjct: 269 ERVALEILETEQAYVRDLKS--IVESEAFDIYTIYCMNYPNSVTVLRDCMKNESLVRFFQ 326
Query: 242 RVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAE---GQGEIKDGLEVMLSVPKK 412
Q PL YL+KPVQRI KY LLL++L + G ++D + M +V
Sbjct: 327 ERQATLCHSLPLETYLLKPVQRILKYHLLLQELSKHFDKSDPGYEVVEDAIITMTAVAWY 386
Query: 413 AND 421
ND
Sbjct: 387 IND 389
>UniRef50_UPI0000E477CD Cluster: PREDICTED: similar to GH10341p; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
GH10341p - Strongylocentrotus purpuratus
Length = 1150
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 24/157 (15%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELD-------KYETM--PED-------VGHCFVTWAREFD 166
D +FGNI+EI +F + FL+ L+ + T+ P++ +G F+ + F
Sbjct: 609 DALFGNIKEIIKF-QTGFLKSLEDPISKEPNFSTLDSPDEFKRILFSLGGSFLYYMEHFK 667
Query: 167 MYVSYCRNKPDSNAAVVQHAGD-----YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLL 331
+Y ++C S + G+ + E K++ LA+YLIKP+QR+ KY LLL
Sbjct: 668 LYSAFCACHSRSQKILDPAKGNSALMQFLEARNPKQQHSASLASYLIKPIQRVLKYPLLL 727
Query: 332 KDLQACCAEGQGE---IKDGLEVMLSVPKKANDAMHL 433
+++ E + + L+ M V + ND M +
Sbjct: 728 SEMRTHLDRDSYEHYHLSEALKGMNKVAEHINDMMRV 764
>UniRef50_UPI0000E47B1C Cluster: PREDICTED: similar to TUBA; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
TUBA - Strongylocentrotus purpuratus
Length = 1790
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 23/140 (16%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMP-EDV-------------GHCFVTWAREF-DM 169
D++FGN+E++ E FL ++D P ED G F+ +R +
Sbjct: 1203 DVLFGNMEQVIEVAES-FLHDIDAAAEKPIEDQLFGELALESGFRRGKIFMDHSRNLHEA 1261
Query: 170 YVSYCRNKPDSNAAVVQH-----AGDYFER---VQRKKKLEHPLAAYLIKPVQRITKYQL 325
Y YCRN D++A + ++ +Y + + R+ LA++LIKPVQRI KY L
Sbjct: 1262 YAQYCRNHDDASALLEKYEENPEVQEYINQGLELVRQSTNCWDLASFLIKPVQRILKYHL 1321
Query: 326 LLKDLQACCAEGQGEIKDGL 385
L+ +L GQ + D L
Sbjct: 1322 LIAELYKYRHRGQEAMSDKL 1341
>UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep:
MGC166429 protein - Bos taurus (Bovine)
Length = 813
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/77 (32%), Positives = 47/77 (61%), Gaps = 3/77 (3%)
Frame = +2
Query: 272 PLAAYLIKPVQRITKYQLLLKDL---QACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLL 442
PL +L +PV+R+ +YQ LLK+L +A + ++ V+ ++P++A + +H+SL+
Sbjct: 30 PLQHFLEQPVERVQQYQALLKELIRNKARNGQNCALLEQAYAVVSALPQRAENQLHVSLM 89
Query: 443 EGCDVPTDSLGEVVLQG 493
E ++LGE + QG
Sbjct: 90 ENYPGTLEALGEPIRQG 106
>UniRef50_Q54GP2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 805
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 7/107 (6%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYE-TMPED---VGHCFVTWAREFDMYVSYCRNKPDSNA 208
+FGNIE + + + ++ KYE ++PED +G ++ +E +YV+Y N ++
Sbjct: 525 LFGNIEALLVISKDLLIKL--KYEFSLPEDQQRIGDLYIEKTKEMKLYVAYINNYENAMT 582
Query: 209 AVVQH---AGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ + +F+ Q + K + + LI PVQRI +Y+LL +++
Sbjct: 583 TLKKIDTLQPKFFKECQSRYKYSLDIGSLLIMPVQRIPRYELLFREI 629
>UniRef50_UPI000049A2CA Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 588
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 17/145 (11%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPED---VGHCFVTWAREFDMYVSYCRNKPDSNA 208
LIF +I I+ +E+ FL+ + +E +G F F MY YC N +S+
Sbjct: 205 LIFSDITTIYSVNEQ-FLKLIKSFECQDYANVLIGQIFNQMGPLFKMYADYCMNYHESDI 263
Query: 209 AVVQHAGDY-----------FERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL---QA 346
+ Q ++ FE + K + ++A+LI PVQR+ +Y+LLL DL
Sbjct: 264 LIRQMEAEHHPFISWYSKQVFENASPQYK-KFKISAFLITPVQRLPRYKLLLADLLKYTP 322
Query: 347 CCAEGQGEIKDGLEVMLSVPKKAND 421
C +K L+++ V N+
Sbjct: 323 ACHPDHENVKQALKLITEVTITVNN 347
>UniRef50_Q553D3 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 1173
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN----KPDSNA 208
+F N++ I + + ++ P +G FV +A F +YV Y N P A
Sbjct: 881 VFSNLKSILQISTEITHLLEERLSVSPVKIGDIFVKFAPIFKIYVEYVNNFDKVAPQLKA 940
Query: 209 AVVQ-HAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE---IK 376
+ +F + K ++ + + LI PVQR +Y+LLL+++ E E IK
Sbjct: 941 MTENPQSKKFFSEQRNKSRVATDINSLLIMPVQRCPRYELLLREILKHTQEDHVEFKNIK 1000
Query: 377 DGLEVMLSVPKKAND 421
E + + K ND
Sbjct: 1001 SAYESIKDINKYIND 1015
>UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:
Protein vav-1 - Caenorhabditis elegans
Length = 1007
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 27/156 (17%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFL------------------RELDKYETMPEDVGHCFVTWARE 160
++IFGNIEEI+ H + R + E +P+ +G F+ + +
Sbjct: 281 NIIFGNIEEINVLHTALLADLEYPVKVALGLSDATPPRPISLNECVPQTIGEVFIKYRDQ 340
Query: 161 FDMYVSYCRNKPDSN--AAVVQHAGDYFER----VQRKKKLEHPLAAYLIKPVQRITKYQ 322
F Y YC N PDS + + ++ R + + + + L P QR+TKY
Sbjct: 341 FLAYGKYCSNLPDSRKLSNELLKTNEFISRNINELTAQGNCKFGMNDLLCVPFQRLTKYP 400
Query: 323 LLLKDLQA---CCAEGQGEIKDGLEVMLSVPKKAND 421
LLLK+LQ + + +++ +EVM V N+
Sbjct: 401 LLLKELQKKTDLASPDRKSLEEAVEVMEDVCNYINE 436
>UniRef50_P91621 Cluster: Protein still life, isoform SIF type 1; n=7;
Endopterygota|Rep: Protein still life, isoform SIF type 1
- Drosophila melanogaster (Fruit fly)
Length = 2072
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 21/122 (17%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED----------------VGHCFVTWAREFDMY 172
+FGNI EI F +R FL+ L++ + D +G F+ + F +Y
Sbjct: 1480 LFGNIHEIVTF-QRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFKLY 1538
Query: 173 VSYCRNKPDSNAAVVQHAGDYFER---VQRKKKLEHP--LAAYLIKPVQRITKYQLLLKD 337
S+C + + + + G++ + R K +H L +YLIKP+QRI KY LLL+
Sbjct: 1539 SSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQ 1598
Query: 338 LQ 343
++
Sbjct: 1599 MR 1600
>UniRef50_UPI0000E4A769 Cluster: PREDICTED: similar to vav 2
oncogene, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to vav 2 oncogene,
partial - Strongylocentrotus purpuratus
Length = 318
Score = 47.6 bits (108), Expect = 2e-04
Identities = 40/111 (36%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLREL-DKYETMPEDVGHCFVTWAREFDMYVSYCRN------- 190
D IF NIEE+ R H R FLR+L D + + H F +F +Y YC +
Sbjct: 189 DKIFLNIEELLRRH-RGFLRDLEDAFRRPTPTMAHAFKKHKPDFLIYGFYCAHMLGAQNH 247
Query: 191 -KPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ SN ++ + FER +K L L P+QRI KY LLLK+L
Sbjct: 248 IEKVSNNPQIRAKIEEFERKANDRKFR--LRDLLSVPMQRILKYHLLLKEL 296
>UniRef50_Q1RMS9 Cluster: FGD6 protein; n=11; Amniota|Rep: FGD6
protein - Bos taurus (Bovine)
Length = 1092
Score = 47.6 bits (108), Expect = 2e-04
Identities = 38/103 (36%), Positives = 52/103 (50%), Gaps = 7/103 (6%)
Frame = +2
Query: 140 FVTWAREFDMYVSY----CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQR 307
+ T+ +EFD ++ C+ P AAVV+ FE R L L YL+KPVQR
Sbjct: 628 YSTYIKEFDKNIALLDEQCKKNPGF-AAVVRE----FEMSPRCANLA--LKHYLLKPVQR 680
Query: 308 ITKYQLLLKDLQACCAEGQGEIK---DGLEVMLSVPKKANDAM 427
I +Y+LLL D E G+ + D L V++ V AND M
Sbjct: 681 IPQYRLLLTDYLKNLLEDSGDYRDTQDALAVVIEVANHANDTM 723
>UniRef50_Q17DC1 Cluster: Still life, putative; n=5;
Endopterygota|Rep: Still life, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 2068
Score = 47.6 bits (108), Expect = 2e-04
Identities = 37/122 (30%), Positives = 60/122 (49%), Gaps = 21/122 (17%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED----------------VGHCFVTWAREFDMY 172
+FGNI+EI F +R FL L++ + D +G F+ + F +Y
Sbjct: 1340 LFGNIQEIVTF-QRQFLSNLEEALDLEPDFHQLEHPSQFKNVLFAIGSAFLYYVNHFKLY 1398
Query: 173 VSYCRNKPDSNAAVVQHAGDYFER---VQRKKKLEHP--LAAYLIKPVQRITKYQLLLKD 337
S+C + + + + G+ + V R K +H L ++LIKP+QRI KY LLL+
Sbjct: 1399 SSFCASHSKAQKVLHPNEGNQALQEFLVARNPKQQHSSTLESFLIKPIQRILKYPLLLQQ 1458
Query: 338 LQ 343
L+
Sbjct: 1459 LR 1460
>UniRef50_UPI000049976C Cluster: hypothetical protein 115.t00004; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein
115.t00004 - Entamoeba histolytica HM-1:IMSS
Length = 948
Score = 47.2 bits (107), Expect = 3e-04
Identities = 31/109 (28%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPE-------DVGHCFVTWAREFDMYVSYCRNKPD 199
+F NI EI+ H+ +F + +++E + D+ + F + +++Y+ Y K D
Sbjct: 679 LFNNIGEIYEIHKTLFKQIEERWEEQKDIPLIIVSDIYNKFFSDKETYNIYMEYY-TKAD 737
Query: 200 S--NAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
S N Q + + ++V K+ P+ +LI+P+QR+ +Y LLLK+L
Sbjct: 738 SGLNFNYQQCSPEVMKQVLEFKQKRIPIDQFLIQPIQRLPRYVLLLKEL 786
>UniRef50_Q6ZV73 Cluster: FYVE, RhoGEF and PH domain-containing
protein 6; n=18; Eumetazoa|Rep: FYVE, RhoGEF and PH
domain-containing protein 6 - Homo sapiens (Human)
Length = 1430
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/103 (36%), Positives = 52/103 (50%), Gaps = 7/103 (6%)
Frame = +2
Query: 140 FVTWAREFDMYVSY----CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQR 307
+ T+ +EFD ++ C+ P AAVV+ FE R L L YL+KPVQR
Sbjct: 966 YSTYIKEFDKNIALLDEQCKKNPGF-AAVVRE----FEMSPRCANLA--LKHYLLKPVQR 1018
Query: 308 ITKYQLLLKDLQACCAEGQGEIK---DGLEVMLSVPKKANDAM 427
I +Y+LLL D E G+ + D L V++ V AND M
Sbjct: 1019 IPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTM 1061
>UniRef50_UPI00015B50AC Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 1; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to FYVE, RhoGEF and
PH domain containing 1 - Nasonia vitripennis
Length = 777
Score = 46.8 bits (106), Expect = 4e-04
Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 25/189 (13%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELD-KYETMPED--VGHCFVTWAREFDMYVSYCRNKP---DS 202
+F NI+ I++FH L +L+ + E D +G +A MY Y +N +
Sbjct: 279 MFSNIKSIYKFHNDFLLPQLETRIEAWDADPRIGDIMKNFAPFLKMYTEYVKNFDYAINL 338
Query: 203 NAAVVQHAGDYFERVQRKKKLEH----PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
+ + Q + + +KL+ LA +++ P+QR+ +Y+LLLKD + +
Sbjct: 339 ISTLQQKVPRFAAIINEIQKLDECAKLSLAHHMLSPIQRLPRYELLLKDYLRNLVKDNPD 398
Query: 371 IKD---GLEVMLSVPKKANDAMH--------LSLLEGCDVPTDSLG---EVVLQGLLSRV 508
+D LE++ + N+AM L + E TD + E+V +G + ++
Sbjct: 399 YEDTKKALELVSTAANHTNEAMKKIDKFKKLLEIQESIYDSTDLVSATRELVKEGRIVKI 458
Query: 509 GP-SSDHQK 532
S DHQ+
Sbjct: 459 SARSGDHQE 467
>UniRef50_UPI0000498C66 Cluster: actin-binding protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: actin-binding
protein - Entamoeba histolytica HM-1:IMSS
Length = 433
Score = 46.8 bits (106), Expect = 4e-04
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Frame = +2
Query: 29 KEDLIFGNIEEIHRFHERVFLRELDK---YETMPEDVGHCFVTWAREFDMYVSYCRNKPD 199
++ +F NIE + + + +VF +L K +G+ F+T+ +Y YC N
Sbjct: 152 EQKTLFSNIETVFQIN-KVFCSDLIKGCCRFNSNTTIGNIFLTFIPFLKVYNEYCSNFRH 210
Query: 200 SNAAV----VQHA-GDYFERVQRKKK--LEHPLAAYLIKPVQRITKYQLLLKDLQACCAE 358
+ + H ++ ++Q K+ + ++ LI PVQR+ +YQLLLKDL +
Sbjct: 211 TIDLIKTLKYPHKFAPFYSKIQYKQSPYSKSSISDLLITPVQRLPRYQLLLKDLLKHTQQ 270
Query: 359 GQ---GEIKDGLEVMLSVPKKANDAMHLSLL 442
IK LE++ V K N+ ++ L
Sbjct: 271 SHIDYNNIKKALEMIQEVANKVNETSKINEL 301
>UniRef50_Q4S0P4 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=7; Clupeocephala|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 974
Score = 46.8 bits (106), Expect = 4e-04
Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 7/109 (6%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPED---VGHCFVTWAREFD-MYVSYCRNKPDSN 205
LI GN+EEI F +++ ++ L++ +PE VG F+ + +Y SYC N P +
Sbjct: 404 LILGNLEEICTF-QQMLVQSLEECTKLPETQQRVGGFFLNLMPQMRALYSSYCSNHPSAV 462
Query: 206 AAVVQHA---GDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQ 343
+ Q + GD+ E L L KP R+ KY LLK+L+
Sbjct: 463 NVLTQQSEVLGDFMEGRGAVSPGILTLTTGLSKPFMRLDKYPTLLKELE 511
>UniRef50_Q7Z6J4 Cluster: FYVE, RhoGEF and PH domain-containing
protein 2; n=22; Theria|Rep: FYVE, RhoGEF and PH
domain-containing protein 2 - Homo sapiens (Human)
Length = 655
Score = 46.8 bits (106), Expect = 4e-04
Identities = 40/144 (27%), Positives = 68/144 (47%), Gaps = 14/144 (9%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFL----RELDKYETMPEDVGHCFVTWAREFDMYVSYCRN--KPD 199
+IF NI I++FH + FL R LD + P +G A MY Y +N +
Sbjct: 149 VIFSNISSIYQFHSQFFLPELQRRLDDWTANPR-IGDVIQKLAPFLKMYSEYVKNFERAA 207
Query: 200 SNAAVVQHAGDYFERVQRKKKLEHP-----LAAYLIKPVQRITKYQLLLKD-LQACCAEG 361
A F+ V + + L ++++PVQRI +Y+LLLK+ +Q A+
Sbjct: 208 ELLATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQA 267
Query: 362 --QGEIKDGLEVMLSVPKKANDAM 427
Q + + L+++ S + +N A+
Sbjct: 268 PDQADAQKALDMIFSAAQHSNAAI 291
>UniRef50_Q54DW7 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 986
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPED--VGHCFVTWAREFDMYVSYCRNKPDSNAA 211
+IFG+IE++ + + D+ T +D +G F A +Y YC N + A
Sbjct: 76 IIFGHIEDLLSLNTELLTSIQDRMTTWYQDKRLGDIFTKMAPYLKVYTEYCGNYDKAVAR 135
Query: 212 VVQHAGD------YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ Q + + + +RV + L + L+ P+QRI +Y+LLL+ L
Sbjct: 136 LKQKSDESRDLQMFLKRVTSENSFGLDLNSLLVTPIQRIPRYKLLLQSL 184
>UniRef50_Q1ZXN6 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=2; Dictyostelium discoideum|Rep: Pleckstrin
homology (PH) domain-containing protein - Dictyostelium
discoideum AX4
Length = 1145
Score = 46.4 bits (105), Expect = 6e-04
Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 9/121 (7%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKY--ETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
+IF NI+ + ++ + L K E VG CF+ + + +Y YC N+ S
Sbjct: 498 IIFSNIQLLLNVNKELLSDLLQKAPDEKPNHTVGTCFIYFFKYLKIYSGYCANQTISADH 557
Query: 212 VVQHAG------DYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
+ + + + E Q + L ++LIKPVQR+ KY LLL++L EG +
Sbjct: 558 IARCSKKIPSFKQFLEEKQASTECRQCNLESFLIKPVQRLCKYPLLLRELIKNSCEGHPD 617
Query: 371 I 373
+
Sbjct: 618 L 618
>UniRef50_Q96M96 Cluster: FYVE, RhoGEF and PH domain-containing
protein 4; n=34; Amniota|Rep: FYVE, RhoGEF and PH
domain-containing protein 4 - Homo sapiens (Human)
Length = 766
Score = 46.4 bits (105), Expect = 6e-04
Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 14/143 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK----YETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
IF NI I+ FH + L EL+K +ET P +G A MY Y + ++
Sbjct: 253 IFSNISSINAFHSKFLLPELEKRMQEWETTPR-IGDILQKLAPFLKMYGEYVKGFDNAME 311
Query: 209 AV------VQHAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKD-LQACCAEG- 361
V + E +Q++K L ++++PVQRI +Y++LLKD L+ +
Sbjct: 312 LVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSL 371
Query: 362 -QGEIKDGLEVMLSVPKKANDAM 427
+ K LE++ + +N A+
Sbjct: 372 DWNDAKKSLEIISTAASHSNSAI 394
>UniRef50_Q6WKY8 Cluster: Guanine nucleotide exchange factor; n=2;
Entamoeba histolytica|Rep: Guanine nucleotide exchange
factor - Entamoeba histolytica
Length = 630
Score = 46.0 bits (104), Expect = 7e-04
Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETM---PEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF +I+ I +E+ FL+ K + +G F+ A +Y YC+N P++
Sbjct: 227 IFSDIQMILSVNEQ-FLQSFQKVISQWNSESKIGGLFIKLAPFLKIYGEYCKNYPEA-LK 284
Query: 212 VVQHAGD-------YFERVQRKKKLEHP---LAAYLIKPVQRITKYQLLLKDLQACCAEG 361
V++ G Y+ +++ E+ L ++LI P+QRI +Y+LLL DL +
Sbjct: 285 VLKELGSGHEFFKFYYSQIRNNAPDEYKNFELTSFLITPIQRIPRYKLLLNDLLKHTPQN 344
Query: 362 QGEIKD---GLEVMLSVPKKAND 421
+ KD G ++ V N+
Sbjct: 345 HPDFKDLSNGFNIVSQVAISVNE 367
>UniRef50_Q9VS45 Cluster: CG8606-PA, isoform A; n=4; Sophophora|Rep:
CG8606-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 647
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 6/107 (5%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVV 217
L+FG IE IH + FLREL E E+V H F+ A F +Y Y + + +
Sbjct: 113 LLFGQIEMIHNLNGE-FLREL---EANMENVAHAFLKMAPFFKLYSVYAFDYRGALFIIQ 168
Query: 218 QHAGD------YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ E+ + + +++ L + +I P+QR+ +Y+LLL+ +
Sbjct: 169 DLISKNPVFRKFLEQTESRPEVQRKLNSLMIVPIQRVPRYKLLLEQV 215
>UniRef50_Q9GTU9 Cluster: Rho guanine nucleotide exchange factor 3;
n=9; Sophophora|Rep: Rho guanine nucleotide exchange
factor 3 - Drosophila melanogaster (Fruit fly)
Length = 1011
Score = 45.6 bits (103), Expect = 0.001
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 13/178 (7%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAV- 214
LIF NI I++F +R FL L + V F+ + F Y +YC P + +
Sbjct: 563 LIFSNITAIYKF-QRKFLEALRR-GIEQNQVAKVFLKMHKGFLCYSTYCNAYPRALIELE 620
Query: 215 ----VQHAGDYFERVQRKKKL-EHPLAAYLIKPVQRITKYQLLLKD-LQACCAEG--QGE 370
V+ A E + + L E PL+A+L+ PVQRI +Y L L + +++ +G +G
Sbjct: 621 TYDRVKDARTILENCRESQNLAELPLSAHLLAPVQRICRYPLHLNEIIKSALEKGAKEGN 680
Query: 371 IKDGLEVMLSVPKKANDAMHLSLLEGCDVP----TDSLGEVVLQGLLSRVGPSSDHQK 532
DG + K D L + E D+P T +L ++G+ V H +
Sbjct: 681 DTDGAK----SAGKTTDYEQLDVTE-LDIPDSQDTVNLALEAMRGITEAVNEGKRHSE 733
>UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1695
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 10/112 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLR-ELDKYETMPEDVGHCFVTWAREF-DMYVSYCRNKPDSNA 208
+++FGN+ + R+ E + +++G CF A E +Y +YC+N D+
Sbjct: 1016 EVLFGNMHSVVETSTRLLGSFEAALQDDKQQELGKCFAEHAEEIKSVYSTYCKNHDDAIG 1075
Query: 209 AVVQHAGDYFERVQRKKKLEH--------PLAAYLIKPVQRITKYQLLLKDL 340
+ ++ + +K L+ L+++LIKPVQR+ KY LLL +L
Sbjct: 1076 LLEKYEDCLEAQEAFRKCLDAVRDTTKCWDLSSFLIKPVQRVLKYPLLLSEL 1127
>UniRef50_Q5JSP0 Cluster: FYVE, RhoGEF and PH domain-containing
protein 3; n=28; Euteleostomi|Rep: FYVE, RhoGEF and PH
domain-containing protein 3 - Homo sapiens (Human)
Length = 725
Score = 45.6 bits (103), Expect = 0.001
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 15/144 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLREL-----DKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSN 205
IF NI IHRFH + L EL ++++T P +G A MY Y +N +
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPR-LGDILQKLAPFLKMYGEYVKNFDRAV 258
Query: 206 AAV---VQHAG---DYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQ 364
V Q + D +Q+++ + L ++++PVQR+ +Y+LLLKD +
Sbjct: 259 GLVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDA 318
Query: 365 GEIKD---GLEVMLSVPKKANDAM 427
+ KD LE++ + +N A+
Sbjct: 319 PDRKDAERSLELISTAANHSNAAI 342
>UniRef50_Q4RFR9 Cluster: Chromosome 16 SCAF15113, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 16
SCAF15113, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1512
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 5/76 (6%)
Frame = +2
Query: 128 VGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHAGD-YFERV--QRKKKLEHP--LAAYLI 292
+G F+ +A F +Y ++C + +V+ D F+ +R K +H L +YLI
Sbjct: 1112 LGGSFLYYADRFKIYSAFCASHTKVPKVLVKAKSDPNFKAFLDERNPKQQHSSTLESYLI 1171
Query: 293 KPVQRITKYQLLLKDL 340
KP+QR+ KY LLLK+L
Sbjct: 1172 KPIQRVLKYPLLLKEL 1187
>UniRef50_A6S9L4 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1066
Score = 45.2 bits (102), Expect = 0.001
Identities = 51/183 (27%), Positives = 83/183 (45%), Gaps = 19/183 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV---GHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF NI I F R FL +++ + P D G F + F +Y + N+ + A+
Sbjct: 303 IFLNINAILDFQRR-FLIKIETTNSQPVDKQEWGLPFRNYEEAFGIYQPFIANQRKA-AS 360
Query: 212 VVQHAGDYFERVQRKKKLE-HPLAAYLIKPVQRITKYQLLLKDLQ---ACCAEGQGEIKD 379
+ + D ++ + L +L+KP+QR+ KY LLLKDL+ E + ++
Sbjct: 361 IAKDNFDKITMADHPVVVDFNTLDGFLLKPMQRLVKYPLLLKDLRDKTNASDEAKEDLTL 420
Query: 380 GLEVMLSVPKKANDAMHL-----SLLEGC-------DVPTDSLGEVVLQGLLSRVGPSSD 523
G+E V +AN A+ +LL+ C + D G+++L G V SD
Sbjct: 421 GIEASNRVLHQANAAVDRELRGEALLDLCGRVDDWKNHRVDHFGDLILHGHFPVVTGKSD 480
Query: 524 HQK 532
QK
Sbjct: 481 VQK 483
>UniRef50_UPI0001555442 Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 2; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to FYVE, RhoGEF and PH
domain containing 2 - Ornithorhynchus anatinus
Length = 644
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 11/111 (9%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFL----RELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSN 205
LIF NI IH+FH + FL R ++ +++ P +G MY + +N +
Sbjct: 268 LIFSNISSIHQFHSQFFLPELQRRMENWDSNPR-IGDVIQKLGPFLKMYSEFVKNFDRAV 326
Query: 206 AAVVQHA------GDYFERVQRKK-KLEHPLAAYLIKPVQRITKYQLLLKD 337
+ + + +QR + + L ++++PVQR+ +Y+LLLKD
Sbjct: 327 ELLAEWTEKCPPFQEIIANIQRSEASAQLSLQHHMLEPVQRVPRYELLLKD 377
>UniRef50_Q4RJT9 Cluster: Chromosome 9 SCAF15033, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
SCAF15033, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 725
Score = 44.8 bits (101), Expect = 0.002
Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED----VGHCFVTWAREFDMYVSYCRNKPDSNA 208
IF NI I+ FH++ L EL T D +G A MY Y +N +
Sbjct: 227 IFSNISSIYCFHDKFLLPELKTRITGEWDSNPRIGDILQKLAPFMKMYGEYVKNFDRAMD 286
Query: 209 AV---VQHAGDYFERVQRKKKLEH----PLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
V Q + + VQ +K E L ++++PVQRI +Y+LLLKD E
Sbjct: 287 LVNTWTQRSSQFKSVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEDAL 346
Query: 368 EIKDGLEVMLSVPKKAN 418
+ KD + + + AN
Sbjct: 347 DRKDAEKALELISTAAN 363
>UniRef50_Q8TER5 Cluster: FLJ00128 protein; n=30; Tetrapoda|Rep:
FLJ00128 protein - Homo sapiens (Human)
Length = 1546
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Frame = +2
Query: 56 EEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYC--RNKPDSNAAVVQHAG 229
E + FH FLREL T P +G CF+ +F +Y Y R+K ++ A + +
Sbjct: 1158 ERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLENGLAALSPSS 1217
Query: 230 DYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKD-LQACCAEGQGEIKD-GLEVMLSV 403
+ + L L +P++++T+Y LL++ L+ E E + G V L
Sbjct: 1218 ------KGSMEAGPYLPRALQQPLEQLTRYGRLLEELLREAGPELSSECRALGAAVQLLR 1271
Query: 404 PKKA--NDAMHLSLLEGCDVPTDSLGEVV 484
++A D + + + GC++ G+++
Sbjct: 1272 EQEARGRDLLAVEAVRGCEIDLKEQGQLL 1300
>UniRef50_Q86HN1 Cluster: Similar to PH (Pleckstrin homology) domain
[Caenorhabditis elegans]; n=2; Dictyostelium
discoideum|Rep: Similar to PH (Pleckstrin homology)
domain [Caenorhabditis elegans] - Dictyostelium
discoideum (Slime mold)
Length = 1165
Score = 44.4 bits (100), Expect = 0.002
Identities = 37/161 (22%), Positives = 74/161 (45%), Gaps = 16/161 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREF-DMYVSYCRNKP------- 196
IF NIE I F E + K+E EDV F+ ++ ++Y+ Y N
Sbjct: 163 IFSNIESIKDFSEELIKDMKKKFEDGSEDVATPFILKEKQVRELYIPYATNHANLVEGLS 222
Query: 197 ---DSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
+ + Q E K KL+ P ++LI PVQR+ +YQ+L ++ +
Sbjct: 223 KMIEKRPMLAQFLQQVKENPLNKSKLDLP--SFLIMPVQRMVRYQMLFNEILKHTEKEHT 280
Query: 368 E---IKDGLEVMLSVPKKANDAM--HLSLLEGCDVPTDSLG 475
+ +++ ++ + + + N+ + H +LL+ ++ ++ +G
Sbjct: 281 DYQRLEEATQMSMLITRTINEQIRRHQNLLKVQEIQSNLIG 321
>UniRef50_A0CSX7 Cluster: Chromosome undetermined scaffold_26, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_26,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1085
Score = 44.4 bits (100), Expect = 0.002
Identities = 43/150 (28%), Positives = 68/150 (45%), Gaps = 13/150 (8%)
Frame = +2
Query: 29 KEDL-IFGNIEEIHRFHERVFLRELDKYETMPED---VGHCFVTWAREFDMYVSYCRNKP 196
K+D+ + NI EI +F+ FL EL K + + V V F Y YC+
Sbjct: 292 KDDIKMMFNIHEILKFNTE-FLSELQKKNNLKDPNAIVMDSIVPLLNGFIFYYEYCKAYE 350
Query: 197 DSNAAVVQH-AGDYFERVQRKKKLEHPLAA-----YLIKPVQRITKYQLLLKDLQACCAE 358
+ Q+ A F++ + ++++ L Y IKPVQR+ KY LL KDL +
Sbjct: 351 QARKITTQYEAIPAFQQCIKDIEVQNLLKGLSLNDYTIKPVQRLPKYVLLFKDLLKHTMQ 410
Query: 359 GQGE---IKDGLEVMLSVPKKANDAMHLSL 439
+ +K+ LE + + K N M + L
Sbjct: 411 SHPDYQNVKNCLETIEKINDKNNSEMDVYL 440
>UniRef50_P98174 Cluster: FYVE, RhoGEF and PH domain-containing
protein 1; n=24; Euteleostomi|Rep: FYVE, RhoGEF and PH
domain-containing protein 1 - Homo sapiens (Human)
Length = 961
Score = 44.4 bits (100), Expect = 0.002
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 14/143 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK----YETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
IF NI I+ FH++ L EL+K ++ P +G A MY Y +N +
Sbjct: 421 IFSNICSIYCFHQQFLLPELEKRMEEWDRYPR-IGDILQKLAPFLKMYGEYVKNFDRAVE 479
Query: 209 AV---VQHAGDY---FERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
V + + + VQ+++ + L ++++PVQRI +Y+LLLKD G
Sbjct: 480 LVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSP 539
Query: 368 EIKD---GLEVMLSVPKKANDAM 427
+ KD LE++ + + +N A+
Sbjct: 540 DSKDAQKSLELIATAAEHSNAAI 562
>UniRef50_UPI0000DA2C9A Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 6; n=1; Rattus norvegicus|Rep:
PREDICTED: similar to FYVE, RhoGEF and PH domain
containing 6 - Rattus norvegicus
Length = 1445
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/150 (28%), Positives = 64/150 (42%), Gaps = 11/150 (7%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRN 190
P PL+ K+D G ++H + + E + D+ FV MY Y +
Sbjct: 893 PDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVAEQQRIADI---FVKKGPYLKMYSMYIKE 949
Query: 191 KPDSNAAVVQHA---GDYFERVQRKKKLEH-----PLAAYLIKPVQRITKYQLLLKDLQA 346
D N A++ F V R+ ++ L YL+KPVQRI +Y+LLL D
Sbjct: 950 F-DKNIALLDEQCKKNSGFATVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLK 1008
Query: 347 CCAE---GQGEIKDGLEVMLSVPKKANDAM 427
E + +D L V++ V AND M
Sbjct: 1009 NLLEDSVDHRDTQDALAVVIEVANHANDTM 1038
>UniRef50_UPI00004992B4 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 696
Score = 44.0 bits (99), Expect = 0.003
Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 10/116 (8%)
Frame = +2
Query: 23 QGKEDLIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKP 196
+ K D+IF + ++ + F L+E + + + +G FV +A F +Y N
Sbjct: 74 KNKLDVIFLHFPDVQSMNSSFFEQLKEQKEKGKLYDCIGSIFVEFAHFFKVYKLIVGNS- 132
Query: 197 DSNAAVVQ------HAGDYFE--RVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
++ AV++ H Y E R++ K++ L +YLI PVQR+ +Y LLL +L
Sbjct: 133 EAVLAVLKDVCSSPHVSRYLEQQRLRINAKVQLDLRSYLITPVQRLPRYNLLLNEL 188
>UniRef50_Q4TC49 Cluster: Chromosome undetermined SCAF7053, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7053,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 481
Score = 44.0 bits (99), Expect = 0.003
Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Frame = +2
Query: 128 VGHCFVTWAREFDMYVSYCRN-----KPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLI 292
+G F+ +A F Y S+C N K A + ++ E + L +YLI
Sbjct: 110 LGGSFLFYADHFKHYGSFCANHIKVQKVLERAKTDRAFKEFLEAKNPTNQHSSSLESYLI 169
Query: 293 KPVQRITKYQLLLKDLQACCAEGQGE---IKDGLEVMLSVPKKANDAMHL 433
KPVQR+ KY LLL++L G E + + L M +V N +
Sbjct: 170 KPVQRLLKYPLLLRELVTLTQPGSPEHTHLAEALRAMEAVAAHVNQMQQI 219
>UniRef50_Q4S5A8 Cluster: Chromosome 19 SCAF14731, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 19
SCAF14731, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1225
Score = 44.0 bits (99), Expect = 0.003
Identities = 33/98 (33%), Positives = 46/98 (46%)
Frame = +2
Query: 140 FVTWAREFDMYVSYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKY 319
+ T+ R+FD V+ + N A + FE R L L YL+KPVQRI +Y
Sbjct: 811 YSTYIRQFDNNVALLDEQCRKNTAFAAVVRE-FEMSPRCASLA--LKHYLLKPVQRIPQY 867
Query: 320 QLLLKDLQACCAEGQGEIKDGLEVMLSVPKKANDAMHL 433
QLLL D E + KD + V + AN A ++
Sbjct: 868 QLLLTDYLKNLPEESADYKDTQAALSIVKEVANHANNI 905
>UniRef50_Q54B37 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 1155
Score = 44.0 bits (99), Expect = 0.003
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 6/112 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
IF NIE+I + +++++ + T +G F + +Y YC S ++ Q
Sbjct: 742 IFSNIEQIWQINKQLYENLISNTLT----IGQVFSNMSDSLKVYSVYCNYHQKSLDSLNQ 797
Query: 221 -----HAGDYFERVQRKKKLEHPLA-AYLIKPVQRITKYQLLLKDLQACCAE 358
+F+++ K +L ++LIKPVQRI KY LLLK+L AE
Sbjct: 798 LLKTPQNESFFDQLLSKPELRGMGPHSFLIKPVQRICKYPLLLKELLKATAE 849
>UniRef50_Q9NR81 Cluster: Rho guanine nucleotide exchange factor 3;
n=67; Fungi/Metazoa group|Rep: Rho guanine nucleotide
exchange factor 3 - Homo sapiens (Human)
Length = 526
Score = 44.0 bits (99), Expect = 0.003
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 8/108 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAV 214
IFG ++ + HE + LR++ K + E VG V W Y SYC N+ + A +
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALL 225
Query: 215 VQHAGDYFERVQRKKKLEHPLAA------YLIKPVQRITKYQLLLKDL 340
D+ + ++ LE P + +L P R+ KY LLL+++
Sbjct: 226 DHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREI 273
>UniRef50_Q504F6 Cluster: Zgc:109904; n=5; Euteleostomi|Rep:
Zgc:109904 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 506
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLR--ELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAV 214
IFG ++ + HE + +R L E ++VG + W + Y++YC N+ + A +
Sbjct: 179 IFGTLDSLIPLHEDLLVRLEGLRGAEKTVQEVGPTMMDWFPCLEAYITYCCNQVGAKALL 238
Query: 215 VQHAGD----YFERVQRKKKLEHPLAA--YLIKPVQRITKYQLLLKDLQ 343
Q D F R+ ++ L +L P R+ KY LLLK++Q
Sbjct: 239 DQKKQDKRVEQFLRLCQESSFSRKLDLWNFLDLPRSRLVKYPLLLKEIQ 287
>UniRef50_Q1ZXH8 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 1316
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 9/136 (6%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK---YETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF IE IHR++ + + + + + + + +G F+ + +Y Y N +S
Sbjct: 502 IFSQIEIIHRYNSLILEKLVSRNKIWYSSGQKIGDIFIEMSAFLKVYTIYVNNYNNSIQT 561
Query: 212 VVQHAG-DYFERVQRKKKLEH--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKD- 379
+ + F + K + + L+A+LI P+QRI +Y LLL+DL E + +D
Sbjct: 562 ITECMEIPKFASLLEKNRNQFGLDLSAFLIAPIQRIPRYILLLQDLLKNTKESHPDHQDL 621
Query: 380 --GLEVMLSVPKKAND 421
L+ M V + N+
Sbjct: 622 SLALKKMKDVAEYVNE 637
>UniRef50_Q9UKW0 Cluster: T-cell lymphoma invasion and metastasis 2;
n=16; Amniota|Rep: T-cell lymphoma invasion and
metastasis 2 - Homo sapiens (Human)
Length = 1077
Score = 43.6 bits (98), Expect = 0.004
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Frame = +2
Query: 128 VGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHAGD-----YFERVQRKKKLEHPLAAYLI 292
+G F+ +A F +Y +C N + + D + + K+ L +YLI
Sbjct: 563 LGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLI 622
Query: 293 KPVQRITKYQLLLKDLQACC---AEGQGEIKDGLEVMLSVPKKAND 421
KPVQR+ KY LLLK+L + +E + + L+ M V N+
Sbjct: 623 KPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 668
>UniRef50_Q9HF59 Cluster: Cdc24; n=2; Saccharomycetaceae|Rep: Cdc24
- Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 761
Score = 43.6 bits (98), Expect = 0.004
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 11/139 (7%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMP---EDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
++F N+ EI F R FL L+ +P + +G F+ F +Y + + NA
Sbjct: 305 MLFPNLNEIIDFQRR-FLVALEINGQVPAQAQRIGALFMHSKHFFKLYEPWSIGQ---NA 360
Query: 209 AVVQHAGDYFERVQRKKKL---EHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQG---- 367
A+ F+++Q ++ + + L ++L+KPVQR+ +Y LLLKDL + +
Sbjct: 361 AI-NFISSSFDKMQSQEFVIGNKMELQSFLLKPVQRLCRYPLLLKDLLKLSVKTKSDVDT 419
Query: 368 -EIKDGLEVMLSVPKKAND 421
E++ LE+ S+ + N+
Sbjct: 420 KELQTALEISKSIARSINE 438
>UniRef50_Q1E796 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 977
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 10/139 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV---GHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF N+ + F +R FL ++++ +PE+ G F+ F Y + N+ +A
Sbjct: 210 IFLNLNNLLDFAQR-FLIRMEQHNALPEESQNWGELFINHQEGFRQYEPFIANQLRCDAV 268
Query: 212 VVQ-----HAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL--QACCAEGQGE 370
++ HA +Q+ L + +KP QR+TKY L+L +L Q + +
Sbjct: 269 CLREWDKIHAAPRSLDLQQMVAQLSTLNGFFVKPFQRLTKYPLMLMELKKQTDREDLSAD 328
Query: 371 IKDGLEVMLSVPKKANDAM 427
I ++++ V +AN A+
Sbjct: 329 ITTAIDIIQLVLDRANSAI 347
>UniRef50_Q54DE0 Cluster: Calmodulin-binding protein; n=2;
Dictyostelium discoideum|Rep: Calmodulin-binding protein
- Dictyostelium discoideum AX4
Length = 1737
Score = 43.2 bits (97), Expect = 0.005
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 10/109 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK-YETMPED--VGHCFVTWAREFDMYVSYCRNKPDSNAA 211
+F NIE + + V L+ L+K + + E+ VG F+ + MY +YC N+ ++
Sbjct: 1433 LFSNIEILFSINMNV-LKALEKDKDPLCENISVGQTFLDMSHYLKMYTTYCSNQQNALKI 1491
Query: 212 VVQHA------GDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKD 337
+ + +Y E PL +++IKPVQRI KY LL+K+
Sbjct: 1492 LEEEKIKNQPFREYLEFCMNDSVCRGLPLNSFIIKPVQRICKYPLLIKE 1540
>UniRef50_A2F0J5 Cluster: Kelch motif family protein; n=1;
Trichomonas vaginalis G3|Rep: Kelch motif family protein
- Trichomonas vaginalis G3
Length = 971
Score = 43.2 bits (97), Expect = 0.005
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 5/104 (4%)
Frame = +2
Query: 44 FGNIEEIHRFHERVFLRELDKY-ETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ 220
FG+I H+ +FL EL + + V FV+ + F++ ++Y N P N +V+
Sbjct: 231 FGSILNCHQ----IFLDELTQLMHSYSTQVAGLFVSHSSMFEVAITYIANYPQINDTIVE 286
Query: 221 HAGDYFERVQ----RKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
R + ++ ++LI PVQRI +YQL ++DL
Sbjct: 287 KCKSNSVRKELLELSNQQNGQDFLSFLITPVQRIPRYQLFIRDL 330
>UniRef50_A6QW04 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 929
Score = 43.2 bits (97), Expect = 0.005
Identities = 35/140 (25%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV---GHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF N+ + F +R FL ++++ +PED+ G F+ F Y + N+ +A
Sbjct: 210 IFLNLNNLLDFAQR-FLIRMEQHNALPEDMQNWGDLFIQHQEGFRQYEPFIANQLRCDA- 267
Query: 212 VVQHAGDYFERVQRKKKLEHPLA------AYLIKPVQRITKYQLLLKDL--QACCAEGQG 367
V Q + + R + +A + +KP QR+TKY L+L +L Q +
Sbjct: 268 VCQREWEKIKAAPRSADFQQMVAQPSTLNGFFVKPFQRLTKYPLMLMELKKQTDREDLVA 327
Query: 368 EIKDGLEVMLSVPKKANDAM 427
++ ++++ +V +AN A+
Sbjct: 328 DVATAIDMVQTVLDQANHAV 347
>UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Intersectin
2 (SH3 domain-containing protein 1B) (SH3P18)
(SH3P18-like WASP associated protein). SPLICE ISOFORM 2;
n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens
"Intersectin 2 (SH3 domain-containing protein 1B)
(SH3P18) (SH3P18-like WASP associated protein). SPLICE
ISOFORM 2 - Takifugu rubripes
Length = 1529
Score = 42.7 bits (96), Expect = 0.007
Identities = 24/58 (41%), Positives = 37/58 (63%)
Frame = +2
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
N+PD + + A DY R K + PL+++L+KP+QRIT+Y L +K++ C AEG
Sbjct: 1161 NEPDFKTFLKKIATDY-----RCKGM--PLSSFLLKPMQRITRYPLHIKNILECTAEG 1211
>UniRef50_Q4SFX7 Cluster: Chromosome 7 SCAF14601, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1982
Score = 42.7 bits (96), Expect = 0.007
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Frame = +2
Query: 128 VGHCFVTWAREFDMYVSYCRN--KPDSNAAVVQHAGDYFERV-QRKKKLEHP--LAAYLI 292
+G F+ +A F +Y ++C + K A + D+ + +R + +H L +YLI
Sbjct: 1479 LGGSFLYYADRFKIYSAFCASHTKVPKVLAKAKTDSDFKTFLAERNPRQQHSSTLESYLI 1538
Query: 293 KPVQRITKYQLLLKDLQACCAEGQGE 370
KP+QR+ KY LLLK+L C + E
Sbjct: 1539 KPIQRVLKYPLLLKELY-CLTDPDSE 1563
>UniRef50_Q54MM3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 971
Score = 42.7 bits (96), Expect = 0.007
Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 13/122 (10%)
Frame = +2
Query: 14 LPLQGK-----EDL--IFGNIEEIHRFHER--VFLRELDKYETMPEDVGHCFVTWAREFD 166
LPL+ K +DL IF N E IH+F+ L E + + +G F
Sbjct: 634 LPLRSKSIISNDDLSTIFSNSEVIHQFNSGFLALLEEKINNWSTNQSIGEVFNYLENSVQ 693
Query: 167 MYVSYCRNKPDSNAAVVQHAGDYFERVQ----RKKKLEHPLAAYLIKPVQRITKYQLLLK 334
Y +Y N +S A+ D + V+ +++K L YLI PVQR+ +Y +LL+
Sbjct: 694 CYSTYVNNYNNSIKALEDCKRDNEKFVEFLADQREKASIELPGYLIMPVQRMPRYVMLLE 753
Query: 335 DL 340
DL
Sbjct: 754 DL 755
>UniRef50_Q54BY9 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 667
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/110 (23%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLR---ELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
+FGN E +++ + + + +LD + ++ + +G F+ Y Y N S
Sbjct: 335 VFGNWERLYKINSDLLVLIQCKLDNW-SIDQTIGDLFIENTDSLFEYTPYVTNYDHSRKL 393
Query: 212 VVQHAG------DYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDL 340
+ + ++ + QR K+ ++ ++++LI+P+QR+ +Y+LLL+DL
Sbjct: 394 LAKLTSGNTNFRNFLDAAQRDKRSKYLDISSFLIQPIQRLPRYELLLRDL 443
>UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersectin 1;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
intersectin 1 - Tribolium castaneum
Length = 1577
Score = 42.3 bits (95), Expect = 0.009
Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV-GHCFVTWAREFDMYVSYCRNKPDSNAAV- 214
IF N + I + + R FL +L + + D+ G + +Y +C + DS A +
Sbjct: 1128 IFLNWQAILQCNRR-FLSDLYDWTSSGSDILGPVISKHLQNMQVYEVFCGKQLDSAALLQ 1186
Query: 215 -VQHAGDYFERVQRKKKLE-----HPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIK 376
+ F + RK + PL+++LIKP+QRIT+Y LL+ + AE + +
Sbjct: 1187 KLTETSTAFRDLMRKCQNNVATKGMPLSSFLIKPMQRITRYPLLISKIIENTAEDHPDYE 1246
Query: 377 DGLEVMLSVPKKAND 421
E + + K ND
Sbjct: 1247 SLQEALRNAEKFLND 1261
>UniRef50_UPI0000499324 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 457
Score = 42.3 bits (95), Expect = 0.009
Identities = 36/148 (24%), Positives = 75/148 (50%), Gaps = 16/148 (10%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYE------TMPEDVGHCFVTWAREFDMYVSYCRNKPD 199
++F ++++R + + L+EL+ + ++ +G F + ++Y +Y N
Sbjct: 53 IVFKGFDDVYRINSNL-LQELNNLKNHVDGKSLDTHLGEAFSQFIPLLNVYKTYVGNTEA 111
Query: 200 SNAAVVQ-HAGDYFERV----QRKKKLEHPL--AAYLIKPVQRITKYQLLLKDLQACCAE 358
AA+ + + F+++ Q K + H L +YLI PVQR+ +Y+LLL+DL E
Sbjct: 112 QFAALDRLESKSSFKKLCFNLQSKISVGHALNLRSYLITPVQRLPRYKLLLEDLIRNTPE 171
Query: 359 GQ---GEIKDGLEVMLSVPKKANDAMHL 433
G +K+ L+ ++S+ N ++ +
Sbjct: 172 GHCDLARLKNALDKVMSINLNVNHSVDI 199
>UniRef50_UPI00006A1ACD Cluster: FYVE, RhoGEF and PH
domain-containing protein 4 (Actin filament- binding
protein frabin) (FGD1-related F-actin-binding protein)
(Zinc finger FYVE domain-containing protein 6).; n=4;
Euteleostomi|Rep: FYVE, RhoGEF and PH domain-containing
protein 4 (Actin filament- binding protein frabin)
(FGD1-related F-actin-binding protein) (Zinc finger FYVE
domain-containing protein 6). - Xenopus tropicalis
Length = 579
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 11/110 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELD---KYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF NI I FH + L EL+ K ++ +G A MY Y +N ++
Sbjct: 48 IFSNISSIQSFHGQFLLPELESRMKEWSISPKIGDILQKLAPFLKMYAEYVKNFDNAMET 107
Query: 212 V-------VQHAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKD 337
+ VQ + E +QR+ K + L +++ PVQRI +Y++LLKD
Sbjct: 108 LRGWMEKSVQFK-NVVEEIQREGKCGNLTLQHHMLGPVQRIPRYEMLLKD 156
>UniRef50_Q6Q427 Cluster: Guanine nucleotide exchange factor; n=4;
Entamoeba|Rep: Guanine nucleotide exchange factor -
Entamoeba dispar
Length = 571
Score = 42.3 bits (95), Expect = 0.009
Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 15/143 (10%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVS------YCR--NK 193
+IFGNI +I ++H + F EL+K ++ + F++++ Y + YC+ N
Sbjct: 289 IIFGNIIDIEKYHHK-FSNELEKCLSLCNEEKLEFISFSDILLKYFTPSMLDLYCKYANN 347
Query: 194 PDSNAAVVQHAG----DYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
D A D V+ H + ++LI+P+QRI +Y LLL+ L C E
Sbjct: 348 VDIGMAKFNELSRTDVDVGCIVKELSSKGHYVPSFLIQPIQRIPRYVLLLESLIKCLPEY 407
Query: 362 QGE---IKDGLEVMLSVPKKAND 421
E IK L + S+ + N+
Sbjct: 408 LDEAKKIKTCLNKIRSIANEINE 430
>UniRef50_A7SEJ8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 634
Score = 42.3 bits (95), Expect = 0.009
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 12/112 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLR---ELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IFG IE + H + ++ + M + +G + W YV YC N+ ++ A
Sbjct: 265 IFGYIETLLEIHSDIIVKLKAARSSADGMTDSIGQIMLEWFPRLSCYVKYCANQFEAKAM 324
Query: 212 VVQ------HAGDYFERVQR---KKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ + + D+ +R Q +KL+ L ++L P R+ KY L+LK +
Sbjct: 325 LDEKMKSDNNVKDFLQRCQASPFSRKLD--LWSFLDSPRSRLVKYPLMLKSI 374
>UniRef50_UPI0000E46C3C Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 1115
Score = 41.9 bits (94), Expect = 0.012
Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 17/168 (10%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLREL-DKYETMPED--VGHCFVTWAREFDMYVSYCRNKPDS- 202
++IF NI I+ FH++ L +L D+ E ++ +G V + +Y Y N +
Sbjct: 618 NIIFSNISTIYEFHKKFLLTQLEDRMEEWEKNPCLGDILVRLSPFLKLYTDYVGNFDKAV 677
Query: 203 ---NAAVVQ--HAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKD-LQACCAEG 361
N +V+ + +Q+K L ++++PVQRI +Y+LLLK+ L+ AE
Sbjct: 678 KCLNTWMVKIPSFASLLQEIQKKPICMFLTLQHHMLEPVQRIPRYELLLKEYLKKLPAES 737
Query: 362 --QGEIKDGLEVMLSVPKKANDAM----HLSLLEGCDVPTDSLGEVVL 487
+ + + L ++ +ND M H + L + D GE ++
Sbjct: 738 VDRTDAERALGLISKAAHHSNDTMQTMDHFAKLMKLNEKIDFNGETII 785
>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 983
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Frame = +2
Query: 53 IEEIHRFHERVFLRELDKYETMPE-DVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHAG 229
+ E+H+ H + + D M ++ F+ +F Y +YC PD+ + + +
Sbjct: 314 VHELHKMHSKFVFKLEDACNRMDGVNISKLFLDCRDDFLKYGNYCARMPDAQVHIDELSR 373
Query: 230 ------DYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLL 331
D E Q++ + L + L+ P QR+ KY LLL
Sbjct: 374 RDAKFKDILEECQKRANSKFTLRSLLVVPFQRVLKYPLLL 413
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +2
Query: 32 EDLIFGNIEEIHRFHERVFLRELDKYETMP-EDVGHCFVTWAREFDMYVSYCRNKPDS 202
++LIF NIEE+H+ H + + D M ++ F+ +F Y +YC PD+
Sbjct: 255 KELIFINIEELHKMHSKFVFKLEDACNRMDGVNISKLFLDCRDDFLKYGNYCARMPDA 312
>UniRef50_A1ZAQ4 Cluster: CG15611-PA, isoform A; n=5;
Sophophora|Rep: CG15611-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 508
Score = 41.9 bits (94), Expect = 0.012
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Frame = +2
Query: 8 VPLPLQG--KEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDM---- 169
+P L G K+ ++ GNI+EI HE+ L + + + D+ F +A F+
Sbjct: 199 LPEALSGETKQKMLLGNIKEILELHEKEILPLMLRNQ---RDLKGLFDEFAAHFEKNSFY 255
Query: 170 -YVSYCRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLK 334
YVS+ K S+ + Q + + Q + K + + ++L++P+QR+T+Y LLL+
Sbjct: 256 CYVSFTMGKK-SSMQLRQDNRLWLQTYQTQIKDKLGIDSFLVQPIQRLTRYPLLLQ 310
>UniRef50_UPI0000D577DA Cluster: PREDICTED: similar to CG7893-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7893-PA, isoform A - Tribolium castaneum
Length = 719
Score = 41.5 bits (93), Expect = 0.016
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 15/152 (9%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAV 214
+++F I ++H H F REL ++ + F+ W F +Y YC N + +
Sbjct: 249 EVVFYKIYDLHEIH-LAFYRELTRFRDPGFRLSSIFMNWRERFLVYGGYCANLTRA-TNL 306
Query: 215 VQHAGDYFER-----VQRKKKLEH---PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE 370
+Q D E V +K+ + L L P+QRI KY LLL+ L E
Sbjct: 307 LQELCDCDENFNATIVAYEKEDNNGRFKLRDVLSVPMQRILKYHLLLEKLIENTDPNDEE 366
Query: 371 IKD---GLEVMLSVP----KKANDAMHLSLLE 445
D E ML V + A D+ HL++++
Sbjct: 367 CNDLRRAREAMLDVAGFINEAARDSEHLAVIQ 398
>UniRef50_UPI00004983B6 Cluster: cell division control protein
CDC24; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell
division control protein CDC24 - Entamoeba histolytica
HM-1:IMSS
Length = 749
Score = 41.5 bits (93), Expect = 0.016
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKY-ETMPEDVGHCFVTWARE--FDMYVSYCRNKPDSNA 208
+IF N+EEI++F+ + FL +L K E M + V E +Y Y N +S
Sbjct: 260 IIFNNMEEIYQFNSK-FLNDLKKATEDMKPNKPWINVYKELEGALSVYTPYLVNYSESIE 318
Query: 209 AVVQHAGDYFER--VQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQ 343
V Q R + ++K + +++YLI P+QR+ +Y LLL +L+
Sbjct: 319 RVEQILCIECVRDALMKEKGNDKDMSSYLIMPIQRLPRYVLLLNELK 365
>UniRef50_Q4SEL7 Cluster: Chromosome 10 SCAF14616, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF14616, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1085
Score = 41.5 bits (93), Expect = 0.016
Identities = 39/114 (34%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPED---VGHCFV-TWAREF--DMYVSYCRNKP 196
D IF I EI HE FL+++ D VG + ++++E +MY +Y N
Sbjct: 98 DEIFFQIPEILEHHEN-FLKQVAGCVAQWHDRQTVGQILIQSFSKETLANMYSAYIDNFL 156
Query: 197 DSNAAV--VQHAGDYF----ERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
++ AV + A F E+ R+ K + L +IKPVQRI +Y+LL+KDL
Sbjct: 157 NAKDAVRTAKEAKPAFHKFLEQSMRENKEKQALGDLMIKPVQRIPRYELLVKDL 210
>UniRef50_A7SS01 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 229
Score = 41.1 bits (92), Expect = 0.021
Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%)
Frame = +2
Query: 23 QGKEDLIFGNIEEIHRFH-------ERVFLRE--LDKYETMPE------DVGHCFVTWAR 157
Q + + G ++EI F ER+ E D ++T+P+ +G F+ +
Sbjct: 32 QAEVKALVGTVDEILDFQITFLSEMERLLSSETGFDAFDTIPQFQNVIYTIGETFLQYTE 91
Query: 158 EFDMYVSYCRNKPDSNAAVVQHAG--------DYFERVQRKKKLEHPLAAYLIKPVQ-RI 310
F +Y ++C S++ VV+ G ++ + K + L +Y IKP+Q RI
Sbjct: 92 HFKLYSAFC----SSHSRVVELLGPGKNEALRNFLDARNPKNQHSGTLESYFIKPIQQRI 147
Query: 311 TKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKA 415
+Y LLL+ + E E K LE ++++ K A
Sbjct: 148 LRYPLLLRTILKLLDETSEEYKVLLEAVVAIEKVA 182
>UniRef50_A2QIY3 Cluster: Complex: the S. pombe proteins scd1; n=8;
Trichocomaceae|Rep: Complex: the S. pombe proteins scd1
- Aspergillus niger
Length = 924
Score = 41.1 bits (92), Expect = 0.021
Identities = 36/140 (25%), Positives = 66/140 (47%), Gaps = 11/140 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPEDV---GHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF N+ + F +R FL ++++ +PE+ G F+ F Y + N+ +
Sbjct: 221 IFLNLNNLLDFAQR-FLIRIEQHYALPEEKQNWGELFIQHEEAFRQYEPFIANQMRCDEI 279
Query: 212 VVQHAGDYFERVQRKKKLEHPLA------AYLIKPVQRITKYQLLLKDL--QACCAEGQG 367
++ D R K L +A + +KP QR+TKY L+L +L Q + +
Sbjct: 280 CLRD-WDKIHMAPRSKDLLQMVAQPATLNGFFVKPFQRLTKYPLMLGELLKQTENPDLRT 338
Query: 368 EIKDGLEVMLSVPKKANDAM 427
+I+ ++ + +V ANDA+
Sbjct: 339 DIQRAIDAIQTVLDSANDAI 358
>UniRef50_UPI0000D55C29 Cluster: PREDICTED: similar to CG8606-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG8606-PA, isoform A - Tribolium castaneum
Length = 426
Score = 40.7 bits (91), Expect = 0.028
Identities = 33/108 (30%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYC---RNKPD-- 199
D++FG+ I++ ++ + +EL K P++V F A F Y Y RN D
Sbjct: 107 DVLFGDFNTIYKVNKEL-RQELRKN---PKNVAGAFSKIAPFFKCYSFYASGFRNSLDIL 162
Query: 200 SNA-AVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
N Q G + E + + +++ L+A LI P+QR+ +Y+LLL L
Sbjct: 163 QNCHRDNQKFGKFLEMQETRPEVQSKLSALLIAPIQRVPRYKLLLSSL 210
>UniRef50_Q4SU01 Cluster: Chromosome 7 SCAF14053, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 7
SCAF14053, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 798
Score = 40.7 bits (91), Expect = 0.028
Identities = 48/203 (23%), Positives = 79/203 (38%), Gaps = 18/203 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPEDV--GHCFVTWAREFDMYVSYCRNKPDS-- 202
D IF I++I H+ + L + E V GH F A + +Y ++ N ++
Sbjct: 247 DTIFYKIQDIFEMHKEFYDALLPSVQQWDEKVTVGHLFQKLASQLGVYKAFVDNYKEAVE 306
Query: 203 NAAVVQHAGDYFERVQRKKKLEHP-----------LAAYLIKPVQRITKYQLLLKDLQAC 349
A HA F+ + K++ P + A L KP+ R+T+ L+L DL
Sbjct: 307 TAEKCSHANLQFQNISENLKVKCPKDSKDSATTVSMEALLYKPIDRVTRSTLVLHDLLKH 366
Query: 350 CAEGQGE---IKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLLSRVGPSS 520
+ + ++D L + + N+ + P ++V G L V SS
Sbjct: 367 TPKDHPDFPLLQDALRISQNFLSSINEEID-PRRTAVTTPKGEARQLVKDGFLVEVSESS 425
Query: 521 DHQKGTREESLLFDLHLAFWRKK 589
+ R L DL L KK
Sbjct: 426 ---RKVRHVFLFTDLLLCAKMKK 445
>UniRef50_A7SKW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1067
Score = 40.7 bits (91), Expect = 0.028
Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 9/137 (6%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREF-DMYVSYCRNKPDSNA 208
++ GN EE+ RF + +F L E + +G F+ A + ++Y++YC N P +
Sbjct: 393 VLCGNFEELVRFQQTLFGILDECAHLPLSSQRIGANFLQIAPQMKELYLTYCANHPRAVE 452
Query: 209 AVVQHAGDYFERVQRKKKLEH---PLAAYLIKPVQRITKYQLLLKDLQACCAEG---QGE 370
+ +++ + ++ K L L KP + KY LLK+L+ +G + +
Sbjct: 453 VLTKYSDELSAFIESKGAPAPGILTLTTSLSKPFCHLDKYPTLLKELERHLEDGHIDELD 512
Query: 371 IKDGLEVMLSVPKKAND 421
K + V ++ N+
Sbjct: 513 TKKAIPVFQNIKTSCNE 529
>UniRef50_A0C114 Cluster: Chromosome undetermined scaffold_140,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_140,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 891
Score = 40.7 bits (91), Expect = 0.028
Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPEDV--GHCFVTWAREFDMYVSYCRNKP----D 199
L+F N+++I+ +++ +++ + G F + + F +Y Y
Sbjct: 89 LLFRNLKQIYLLNKQFLFEISERFSNFTQHTCFGKIFDKYVQFFKIYFEYTSGFSIEVVS 148
Query: 200 SNAAVVQHAGDYFERVQRKKKLEHP-LAAYLIKPVQRITKYQLLLKDL 340
S + D+ ++ + L +YLIKPVQR+ KY LLLKDL
Sbjct: 149 SLRKEIPKLNDFISELEEADIFKGGNLESYLIKPVQRLPKYVLLLKDL 196
>UniRef50_O94887 Cluster: FERM, RhoGEF and pleckstrin
domain-containing protein 2; n=50; Euteleostomi|Rep:
FERM, RhoGEF and pleckstrin domain-containing protein 2 -
Homo sapiens (Human)
Length = 1054
Score = 40.7 bits (91), Expect = 0.028
Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 19/181 (10%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMPE--DVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
L+F NI+ I+ FH R FLRE+++ + E H + R D+ + R + +
Sbjct: 578 LLFSNIDPIYEFH-RGFLREVEQRLALWEGPSKAHTKGSHQRIGDILLRNMRQLKEFTSY 636
Query: 212 VVQH---AGDYFERVQRKKKLEH-------------PLAAYLIKPVQRITKYQLLLKDLQ 343
+H + + +R KKLE PL +L+KP+QR+ Y+LLL+ L
Sbjct: 637 FQRHDEVLTELEKATKRCKKLEAVYKEFELQKVCYLPLNTFLLKPIQRLLHYRLLLRRLC 696
Query: 344 ACCAEGQGEIKDGLEVMLSVPKKANDAMHLSL-LEGCDVPTDSLGEVVLQGLLSRVGPSS 520
+ G + D + + ++ + H+ + LE T+ ++V G+ + + P
Sbjct: 697 GHYSPGHHDYADCHDALKAITEVTTTLQHILIRLENLQKLTELQRDLV--GIENLIAPGR 754
Query: 521 D 523
+
Sbjct: 755 E 755
>UniRef50_A5DJC8 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 718
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Frame = +2
Query: 275 LAAYLIKPVQRITKYQLLLKDL---QACCAEGQGEIKDGLEVMLSVPKKANDA 424
L +Y++KPVQR+ KY LLLK+L + G E+ LE M V K N+A
Sbjct: 395 LHSYVLKPVQRLCKYPLLLKELVKSTSTLNPGYEELTLALEAMKEVAHKVNEA 447
>UniRef50_UPI00005887C8 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor 3; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor 3 - Strongylocentrotus
purpuratus
Length = 399
Score = 39.9 bits (89), Expect = 0.048
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTW-AREFDMYVSYCRNKPDSN 205
++IFG++EE+ HE + L++ E+VG + W ++YV+YC N+ +
Sbjct: 104 NIIFGSLEELRMIHEELVCDLQKQRGNNGATEEVGKVLLKWLPLVTEVYVTYCTNQLAAK 163
Query: 206 AAVVQ-----HAGDYFER-VQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ + D+ ER ++ + L +L P R+ KY LL K++
Sbjct: 164 TLLDEKKQDSKVNDFLERCIESPFSRKLDLWNFLDVPRSRLVKYPLLFKNI 214
>UniRef50_Q4SCD4 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14659,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 787
Score = 39.9 bits (89), Expect = 0.048
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Frame = +2
Query: 254 KKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE---IKDGLEVMLSVPKKAND 421
KK + PL YL+ P+QRI KY LLLK+L + + +++ L+ M +V N+
Sbjct: 57 KKSTDIPLEGYLLTPIQRICKYPLLLKELLKRTPKKHADYPAVEEALQAMKAVCSNINE 115
>UniRef50_Q54VX2 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 1137
Score = 39.9 bits (89), Expect = 0.048
Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Frame = +2
Query: 20 LQGKEDL--IFGNIEEIHRFHERVFL---RELDKYETMPEDVGHCFVTWAREFDMYVSYC 184
L +ED+ IFG I+ I + + LDK+ T +G CF T Y Y
Sbjct: 540 LISQEDVKFIFGGIDSISAINNTLMNDIESVLDKW-TPYSVLGSCFTTMGVYLKAYTDYV 598
Query: 185 RNKPDSNAAVVQHAGD-----YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+N + Q D + + + K L + LI PVQRI +Y LLL+DL
Sbjct: 599 KNFDFGLQRICQCGKDSKFTAFIKAAEEKTVPRSRLESLLITPVQRIPRYVLLLQDL 655
>UniRef50_Q54J14 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 928
Score = 39.9 bits (89), Expect = 0.048
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 10/110 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMPED----VGHCFVTWAREFDMYVSYCRNKPDSNA 208
IF N EE++ +++ L+ + ++ + F+ ++ F Y SY + N
Sbjct: 531 IFSNFEEVYHISLKIYPMLLNCIPLLEKNQYPNIEEVFLFNSKSFQRYGSYLSSHDSCNK 590
Query: 209 AVV------QHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ Q A F+++ KL + L ++LIKP QR+ KY LLLK+L
Sbjct: 591 FLQEILLTNQTAAQIFQKLIPICKLNN-LHSFLIKPCQRLCKYPLLLKEL 639
>UniRef50_A7S9N2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1363
Score = 39.9 bits (89), Expect = 0.048
Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 12/115 (10%)
Frame = +2
Query: 119 PEDVGHCFVTWAREFDMYVSYCRNKPDS----NAAVVQHAG--DYFERVQRKKKLEH--P 274
P D+ F + + F+ Y++YC + ++++ Y + + +
Sbjct: 498 PMDMNEAFPMFDKRFEPYITYCMEESRCLKYFKEKIIENEDFRTYITWCEEHRLCTNRLK 557
Query: 275 LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVML----SVPKKANDAM 427
L YL+KP+QR+TKY LLLK + + E+K+G+ M+ S+ K N AM
Sbjct: 558 LTDYLVKPMQRLTKYPLLLKAIHKKTQD--EEMKEGIWKMILTVESLLSKVNGAM 610
>UniRef50_A7S9L2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 469
Score = 39.9 bits (89), Expect = 0.048
Identities = 32/143 (22%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Frame = +2
Query: 23 QGKEDLIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWARE-FDMYVSYCRNK 193
+ ++ ++FGN++ + E+ LR+ + + + A + FD+Y+ YC ++
Sbjct: 67 KSQQRVLFGNVKGVLEASEKFLTALRQRQRKSYVISTISDIIEEHATQYFDIYIKYCSHQ 126
Query: 194 PDSNAAVVQHAGDYFERVQRKKKLEHPLAA-------YLIKPVQRITKYQLLLKDLQACC 352
+ +++ G V+ ++LE A +L+ P+QRIT+ LL+ + C
Sbjct: 127 VYQDR-ILKELGKNPRFVEAVRRLEQCSTAQCLSFQSFLVLPMQRITRLPLLVDAICHRC 185
Query: 353 AEGQGEIKDGLEVMLSVPKKAND 421
EG E + + S+ K +D
Sbjct: 186 EEGSDEFVRTDKALKSINKVVHD 208
>UniRef50_A5E275 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 949
Score = 39.9 bits (89), Expect = 0.048
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 7/123 (5%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELDKYETMP---EDVGHCFVTWAR-EFDMYVSYCRNKPDSN 205
++F NI EI F R FL L+ +P + +G F+ + F Y + + +N
Sbjct: 362 MLFPNITEIVDFQRR-FLNGLESNINVPVKYQRLGSVFIHASLGPFKAYEPWTIGQLAAN 420
Query: 206 AAVVQHAGDYFERVQRKKKLEHP---LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIK 376
+++ A + +++ L P L ++++KP+QR+ KY LLLK+L E +
Sbjct: 421 DLIIKEAAN----LRKSSTLIDPGFELQSFILKPIQRLCKYPLLLKELIKHSPEASSKSS 476
Query: 377 DGL 385
D +
Sbjct: 477 DAI 479
>UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep:
Protein vav-2 - Homo sapiens (Human)
Length = 878
Score = 39.9 bits (89), Expect = 0.048
Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 10/137 (7%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYETMP-EDVGHCFVTWAREFDMYVSYCRNKPDSNAAVV 217
+F N+E++ + H FLR +D + + F+ + +Y YC + + +
Sbjct: 240 VFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLN 298
Query: 218 QHAG---DYFERVQ----RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAE--GQGE 370
Q D+ ++V+ + + + L L+ P+QR+ KY LLLK+L + AE + +
Sbjct: 299 QLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQ 358
Query: 371 IKDGLEVMLSVPKKAND 421
+K+ LE M + N+
Sbjct: 359 LKEALEAMQDLAMYINE 375
>UniRef50_UPI0000DB6CBB Cluster: PREDICTED: similar to dynamin
binding protein; n=1; Apis mellifera|Rep: PREDICTED:
similar to dynamin binding protein - Apis mellifera
Length = 1021
Score = 39.5 bits (88), Expect = 0.064
Identities = 32/134 (23%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF---LRELDKYETMPEDVGHCFVTWAREFD-MYVSYCRNKPDSNA 208
+FGN+ ++ + E + L+ + + + +G CF+ + +YV YC N
Sbjct: 456 LFGNLYDVIQVAEELLDMILKAMKGCDEELQTIGPCFIEMNEKLKGVYVKYCGN------ 509
Query: 209 AVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE---IKD 379
H R + +++ LIKPVQRI KY L+L +L C + + +++
Sbjct: 510 ----HEAALGIETLRYQIACFDMSSILIKPVQRILKYPLILYELVKCTEDNHPDKYTVEE 565
Query: 380 GLEVMLSVPKKAND 421
+ M +V N+
Sbjct: 566 AWKTMTAVASHINE 579
>UniRef50_UPI0000499FFA Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 631
Score = 39.5 bits (88), Expect = 0.064
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 10/95 (10%)
Frame = +2
Query: 86 FLRELDKY---ETMPEDVGHCFVTWAREFDMYVSYCRNKP---DSNAAVVQH--AGDYFE 241
FL++++ Y +T+ V CF + +Y + N + AA+ + + E
Sbjct: 93 FLKDMESYRNNKTLENKVVDCFKRFIPYLKVYKMFIGNNEICLHALAAIEKSPIVVSFLE 152
Query: 242 --RVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
R++ K + PL + LI PVQRI +Y LLLKDL
Sbjct: 153 QCRIKIPSKSQQPLRSILIMPVQRIPRYVLLLKDL 187
>UniRef50_Q54UJ2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 651
Score = 39.5 bits (88), Expect = 0.064
Identities = 28/104 (26%), Positives = 50/104 (48%)
Frame = +2
Query: 29 KEDLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
K + IF NIEEI H ++ + + ET P + ++ +F +Y Y +N ++
Sbjct: 75 KVNNIFSNIEEIRELHITIYNKLI---ETKPLIITELYLEMLPKFTIYYPYVKNYNNAYK 131
Query: 209 AVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ + E Q + + L ++LI PVQ+ +Y LL +L
Sbjct: 132 IYSTLSEEDEEFAQLAESFGY-LPSFLILPVQQTPRYLLLFSEL 174
>UniRef50_A0E1W1 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_74,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 866
Score = 39.5 bits (88), Expect = 0.064
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Frame = +2
Query: 14 LPLQGKE---DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFDMYVSYC 184
LP++ E IF N+ +I + +++ + + K + + + F+ Y YC
Sbjct: 66 LPMRSDEKYISAIFMNVSDIRKENQKFYDQVKSKAANINRNSVIFDNVDVKGFETYYHYC 125
Query: 185 RNKPDSNAAV---VQHAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDL 340
RN DS A+ +Q ++ ++ + L +L+KPVQR+ KY L K+L
Sbjct: 126 RNYNDSLKALKLLLQKQPQLEHSLKNRENMRGLQLVDFLVKPVQRLPKYVLFWKEL 181
>UniRef50_Q9UTR5 Cluster: Rho1 guanine nucleotide exchange factor 2;
n=1; Schizosaccharomyces pombe|Rep: Rho1 guanine
nucleotide exchange factor 2 - Schizosaccharomyces pombe
(Fission yeast)
Length = 1158
Score = 39.5 bits (88), Expect = 0.064
Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKP------ 196
+F NI +IH + R+ L + + +G F+ + +F+ ++ Y N+
Sbjct: 495 VFHNIMQIHAVNSRLSNALNRTQTLQPVVNTIGDLFLDYVPKFEPFIKYGANQAIAKFEF 554
Query: 197 DSNAAVVQHAGDYF---ERVQRKKKLEHPLAAYLIKPVQRITKYQLLL 331
+ + ++ +Y ER++ +KLE L YL KP R+ +Y LLL
Sbjct: 555 EREKSTNRNFANYVHEVERLRESRKLE--LNGYLTKPTTRLARYPLLL 600
>UniRef50_A0D0E6 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 544
Score = 39.1 bits (87), Expect = 0.085
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 10/106 (9%)
Frame = +2
Query: 44 FGNIEEIHRFHERVFLRELDKYETMPED---VGHCFVTWAREFDMYVSYCRNKPDSNAAV 214
F NI +I+ + + FLREL K + VG F+ + F MY Y + ++
Sbjct: 123 FSNISQIYDLN-KTFLRELQKKLEFYHNNVCVGQIFLKYIPFFKMYFQYLQEFNIDQISI 181
Query: 215 VQHAGDYFERVQRKKKLEHP-------LAAYLIKPVQRITKYQLLL 331
+++ F+ K LE L ++LIKPVQR+ +Y LL+
Sbjct: 182 LRNQYQDFDNFL--KNLEEACVFKGGDLNSFLIKPVQRLPRYSLLI 225
>UniRef50_Q96PE2 Cluster: Rho guanine nucleotide exchange factor 17;
n=21; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 17 - Homo sapiens (Human)
Length = 2063
Score = 39.1 bits (87), Expect = 0.085
Identities = 17/36 (47%), Positives = 26/36 (72%)
Frame = +2
Query: 233 YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ E+ R+ K + L+ +IKPVQRI +Y+LL+KDL
Sbjct: 1188 FLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDL 1223
>UniRef50_UPI000049A230 Cluster: hypothetical protein 13.t00058;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 13.t00058 - Entamoeba histolytica HM-1:IMSS
Length = 558
Score = 38.7 bits (86), Expect = 0.11
Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 14/119 (11%)
Frame = +2
Query: 26 GKEDL--IFGNIEEIHRFHERVFLRELDKYETMPE---DVGHCFVTWAREFDMYVSYCR- 187
G EDL +F ++I F++++ LRE Y E VG F+ F++Y+ Y +
Sbjct: 45 GSEDLRKMFMYYQDIIEFNKQL-LREFKDYLEKGELIKYVGTVFIANENHFNVYIKYFKA 103
Query: 188 --NKPDSNAAVVQHAGDYF-----ERVQRKKKLE-HPLAAYLIKPVQRITKYQLLLKDL 340
+ + +V + F + + KK ++ L +YLI PVQR+ +YQ+LL L
Sbjct: 104 STKRQEVYGRIVNNLQQNFYLRSIQETEYKKGIQLQSLDSYLILPVQRLPRYQMLLIQL 162
>UniRef50_UPI000065F5D5 Cluster: Rho guanine nucleotide exchange
factor (GEF) 17; n=1; Takifugu rubripes|Rep: Rho guanine
nucleotide exchange factor (GEF) 17 - Takifugu rubripes
Length = 1756
Score = 38.7 bits (86), Expect = 0.11
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +2
Query: 233 YFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ E+ R+ K + L +IKPVQRI +Y+LL+KDL
Sbjct: 897 FLEQSMRENKEKQALGDLMIKPVQRIPRYELLVKDL 932
>UniRef50_Q4SSS2 Cluster: Chromosome undetermined SCAF14347, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14347,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 650
Score = 38.7 bits (86), Expect = 0.11
Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDK----YETMPEDVGHCFVTWAREFDMYVSYCRNKPDSN- 205
IF N+ I+ FH + L +L+ + P +GH + MY Y RN +
Sbjct: 92 IFSNVSSIYSFHSQFLLPDLETCLRCWSERP-GLGHVLLQHGPFLRMYADYVRNFDQAVE 150
Query: 206 -AAVVQHAGDYFERVQRKKKLEH-----PLAAYLIKPVQRITKYQLLLKD 337
V F + + + + L ++++PVQRI +Y+LLLKD
Sbjct: 151 LVRVWNERSAAFRSITQDIQSQEVCGSLSLQHHMLEPVQRIPRYELLLKD 200
>UniRef50_Q54J11 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1166
Score = 38.7 bits (86), Expect = 0.11
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 14/115 (12%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELD-----KYETMPEDVGHCFVTWAREFDMYVSYCRNKPDS- 202
IF NIEE++ R++ L+ +E ++ F+ ++ F Y SY S
Sbjct: 669 IFSNIEELYYVSLRLYPMLLNIIPVLDHENQYPNIEEIFLYNSKAFQRYGSYLSTHDHSI 728
Query: 203 ---NAA-----VVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQ 343
N+ VV Y + + K+L L ++LIKP QR+ KY LLL++L+
Sbjct: 729 KVLNSLIDGNNVVNQIFQYVKSLPHSKQLN--LQSFLIKPCQRLCKYPLLLRELK 781
>UniRef50_Q18372 Cluster: Putative uncharacterized protein exc-5;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein exc-5 - Caenorhabditis elegans
Length = 844
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 14/143 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLREL-----DKYETMPEDVGHCFVTWAREFDMYVSYCRN----- 190
+ N+ +++FH FL +L D + T + + + A MY Y N
Sbjct: 341 LLANVSSLYQFHNTHFLPQLLESIRDWHTT--KRIANVVRKQAPFLKMYSEYTNNYDRAT 398
Query: 191 KPDSNAAVVQHAGDYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
K + D + ++++ + E PL +LI PVQR+ +YQLLL++ +
Sbjct: 399 KLFEELKKKKKFADVVKEIEKQAECEGLPLGHHLICPVQRVMRYQLLLQEYKKHLQPSDV 458
Query: 368 EIKD---GLEVMLSVPKKANDAM 427
+ D LE++L AN+ M
Sbjct: 459 DFDDTTVALELVLQAAAHANEMM 481
>UniRef50_A0CZ33 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 938
Score = 38.7 bits (86), Expect = 0.11
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPED--VGHCFVTWAREFDMYVSYCRNKPDSNA 208
++IF N+++++ + FL++L+ + +G A F +Y Y S A
Sbjct: 117 EIIFNNLQQLYELNSS-FLQDLEGFLPYNRSKLLGPIIKGLAPFFKVYFPYYEGFNKSMA 175
Query: 209 AVVQHAGD------YFERVQRKKKLEHP-LAAYLIKPVQRITKYQLLLKDL 340
+ Q D + + + K + + ++LIKPVQRI KY LLL+DL
Sbjct: 176 TLKQCINDKEDFRKFLKNMSSIKDYNNQDIDSFLIKPVQRIPKYNLLLEDL 226
>UniRef50_Q5KI94 Cluster: GrfA protein, putative; n=2; Filobasidiella
neoformans|Rep: GrfA protein, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 1314
Score = 38.7 bits (86), Expect = 0.11
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 6/55 (10%)
Frame = +2
Query: 254 KKKLEHP------LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLS 400
KK EHP L +YL+ P+QR+ +Y+LLL +L C ++D L+ L+
Sbjct: 1085 KKAREHPMHSQISLESYLLLPIQRVPRYKLLLTELAMCTPARSDGLRDALDDALT 1139
>UniRef50_A1DEX6 Cluster: Rho guanyl nucleotide exchange factor
(Rom2), putative; n=18; Pezizomycotina|Rep: Rho guanyl
nucleotide exchange factor (Rom2), putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 1199
Score = 38.7 bits (86), Expect = 0.11
Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Frame = +2
Query: 11 PLPLQGKEDLI---FGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYV 175
P+P +E I FGN E+ + + + L K + + VG F+ FD ++
Sbjct: 539 PIPEHRREKFIRTVFGNCLEVLKVNGALCEALNARQKESPVVKTVGDIFLQHVPNFDPFI 598
Query: 176 SYCRNK----------PDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQL 325
Y N+ SN A + + ER++ +KLE L YL KP R+ +Y L
Sbjct: 599 KYGANQLYGKYEFEKEKASNPAFARFVEET-ERLKESRKLE--LNGYLTKPTTRLARYPL 655
Query: 326 LLKDLQACCAEGQGEIKD 379
LL+ + +G + +D
Sbjct: 656 LLEQVVKNTKDGNPDKED 673
>UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep:
Intersectin-2 - Homo sapiens (Human)
Length = 1696
Score = 38.7 bits (86), Expect = 0.11
Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 12/118 (10%)
Frame = +2
Query: 23 QGKEDLIFGNIEEIHRFHERVF----LRELDKYETMP-EDVGHCFVTWAREFDMYVSYCR 187
+G+ LIF N +E+ + ++ +R+ E MP + +G Y+ +C
Sbjct: 1246 EGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCS 1305
Query: 188 NKPDSNAAVVQHAGDYFERVQRKKKLEH-------PLAAYLIKPVQRITKYQLLLKDL 340
+ + A + Q + + + KKL PL+++L+KP+QRIT+Y LL++ +
Sbjct: 1306 CQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSI 1363
>UniRef50_UPI0000E49080 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 898
Score = 38.3 bits (85), Expect = 0.15
Identities = 19/40 (47%), Positives = 28/40 (70%)
Frame = +2
Query: 239 ERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAE 358
E+ R K+L+ L LI P+QRITKY LLL+D++ C ++
Sbjct: 763 EQDSRCKRLQ--LTDLLITPIQRITKYTLLLRDIRNCTSQ 800
>UniRef50_A0MTB7 Cluster: Intersectin 1-like protien; n=1;
Trichinella spiralis|Rep: Intersectin 1-like protien -
Trichinella spiralis (Trichina worm)
Length = 327
Score = 38.3 bits (85), Expect = 0.15
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 11/113 (9%)
Frame = +2
Query: 272 PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKK--------ANDAM 427
PL YL+ P+ R TKY L+L+ L + Q + D LE +S K+ A++A
Sbjct: 182 PLNYYLLLPMTRFTKYPLMLQQLLKQTSPAQAD-HDHLEQAVSALKQLCVKVNRLASEAE 240
Query: 428 HLSLLEGCD--VPTD-SLGEVVLQGLLSRVGPSSDHQKGTREESLLFDLHLAF 577
++ +L C V D ++ ++V GL +R+GP G +++ L +AF
Sbjct: 241 NVHMLHWCQNHVRCDNTVPKLVFNGLTNRLGPRQFLHAGPLQKAKSGRLLVAF 293
>UniRef50_Q9Y7U6 Cluster: Rho1 guanine nucleotide exchange factor 1;
n=1; Schizosaccharomyces pombe|Rep: Rho1 guanine
nucleotide exchange factor 1 - Schizosaccharomyces pombe
(Fission yeast)
Length = 1334
Score = 38.3 bits (85), Expect = 0.15
Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 15/141 (10%)
Frame = +2
Query: 2 ASVPLPLQGKEDLI---FGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFD 166
AS +P + KE I F N E+ + ++ L + Y+ + +++ F+ +F+
Sbjct: 653 ASSCIPERKKEKFIRTVFLNALEVQAVNSKLAEALTKRQNYKPIVDNIADIFLEHVPKFE 712
Query: 167 MYVSY----------CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITK 316
++ Y + SN A + D ER++ +KLE L YL KP R+ +
Sbjct: 713 PFIRYGAGQLYGKYEFEKEKSSNPAFAKFVSDV-ERLKESRKLE--LNGYLTKPTTRLAR 769
Query: 317 YQLLLKDLQACCAEGQGEIKD 379
Y LLL+ + EG + +D
Sbjct: 770 YPLLLEAVLKYTDEGNPDKQD 790
>UniRef50_UPI0000E48DF2 Cluster: PREDICTED: similar to Bcr protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Bcr protein - Strongylocentrotus purpuratus
Length = 856
Score = 37.9 bits (84), Expect = 0.20
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 10/122 (8%)
Frame = +2
Query: 5 SVPLPLQGKEDLIFGNIEEIHRFHERVFLRELDKY--ETMPEDV-GHCFVTWAREFDMYV 175
S P+ + D +F I E+ H R F+ ++ E PE + G F A FD++
Sbjct: 109 SDPVMTDEEYDTMFFRIPELFNVH-RQFVNHMEPKMKEWTPEQMQGDSFKLLASHFDIHE 167
Query: 176 SYCRN--KPDSNAAVVQHAGDYFERV-QRKKKLE----HPLAAYLIKPVQRITKYQLLLK 334
Y N + S +Q + F + Q+ KL + L A L P+Q ITK ++L
Sbjct: 168 EYIANYKRAMSTLQHLQSENELFRNIAQQALKLSSGEMYTLEAMLYSPLQGITKLTMILN 227
Query: 335 DL 340
DL
Sbjct: 228 DL 229
>UniRef50_Q6FIT2 Cluster: Candida glabrata strain CBS138 chromosome
M complete sequence; n=2; Saccharomycetales|Rep: Candida
glabrata strain CBS138 chromosome M complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 840
Score = 37.9 bits (84), Expect = 0.20
Identities = 36/136 (26%), Positives = 65/136 (47%), Gaps = 8/136 (5%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVFLRELD---KYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNA 208
++F N+ E F R FL L+ E + +G F+ F +Y + + NA
Sbjct: 371 MLFPNLGEAIDFQRR-FLASLEINALVEPSKQRIGALFMHSKYFFKLYEPWSIGQ---NA 426
Query: 209 AVVQHAGDYFERVQRKK---KLEHPLAAYLIKPVQRITKYQLLLKDL--QACCAEGQGEI 373
A+ + ++V + K + L ++L KPVQR+ +Y LLL++L Q+ + E+
Sbjct: 427 AI-EFLSSTLQKVSEEDFVIKNKMELQSFLYKPVQRLCRYPLLLRELAQQSVNDKSAKEL 485
Query: 374 KDGLEVMLSVPKKAND 421
LE+ S+ + N+
Sbjct: 486 DAALEISRSIARSINE 501
>UniRef50_A2F021 Cluster: RhoGEF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: RhoGEF domain containing
protein - Trichomonas vaginalis G3
Length = 802
Score = 37.5 bits (83), Expect = 0.26
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
Frame = +2
Query: 131 GHCFVTWAREFDMYVSYCRNKPDSNAAVVQ-HAGDYFERVQRK---KKLEHPLAAYLIKP 298
G+CF M+V Y + P+ + ++ + A + R+ + KK P+++ +I P
Sbjct: 560 GNCFTNAKHLIKMFVPYIEHYPEIDLSIKKLTAMNKKFRIACEAVVKKGVQPISSLVIMP 619
Query: 299 VQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKANDA 424
VQR+ KY LLL+++ E E + LE ++ K+A+ A
Sbjct: 620 VQRMPKYVLLLREIYKATPEWH-EDRKLLEDAMASLKEASSA 660
>UniRef50_Q6CDY6 Cluster: Similar to tr|Q9Y7U6 Schizosaccharomyces
pombe Rho1 gdp-gtp exchange protein 1; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q9Y7U6 Schizosaccharomyces
pombe Rho1 gdp-gtp exchange protein 1 - Yarrowia
lipolytica (Candida lipolytica)
Length = 1313
Score = 37.5 bits (83), Expect = 0.26
Identities = 33/143 (23%), Positives = 66/143 (46%), Gaps = 15/143 (10%)
Frame = +2
Query: 38 LIFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWAREFDMYVSY---------- 181
++F I ++H + ++ L + +++ + VG F+ F+ ++ Y
Sbjct: 655 MVFSFIMDVHAVNIKLAEALTKREQFAPVVRRVGDIFLQHVPRFEPFIKYGASQLYGKYE 714
Query: 182 CRNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEG 361
+ SN A + D ER+++ +KLE L YL KP R+ +Y LLL+ + E
Sbjct: 715 YEREKSSNPAFAKFVNDT-ERLEQSRKLE--LNGYLTKPTTRLARYPLLLEAVLKHTKED 771
Query: 362 Q---GEIKDGLEVMLSVPKKAND 421
G+I + ++ + + K N+
Sbjct: 772 NPDYGDIPEAIKQIKAYLMKVNE 794
>UniRef50_A3LN99 Cluster: Gdp-GTP Exchange Protein (GEP) for the
Rho1p Small GTP-binding Protein; n=5;
Saccharomycetales|Rep: Gdp-GTP Exchange Protein (GEP)
for the Rho1p Small GTP-binding Protein - Pichia
stipitis (Yeast)
Length = 896
Score = 37.5 bits (83), Expect = 0.26
Identities = 25/107 (23%), Positives = 52/107 (48%), Gaps = 10/107 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERV---FLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKP----- 196
+FG + ++ R + + R + + + E +G F+ + F+ ++ Y NK
Sbjct: 242 VFGGVGDLLRLAKNMSEALTRRQQQQKPVVETLGDVFLDYVGNFEPFIRYSGNKVFASFE 301
Query: 197 -DSNAAVVQHAGDYFERVQRK-KKLEHPLAAYLIKPVQRITKYQLLL 331
+ V + + +++K + + L+++LIK VQR +YQLLL
Sbjct: 302 HERQQQVNMRYARFLDAIEKKPESRKQDLSSFLIKGVQRPARYQLLL 348
>UniRef50_P52746 Cluster: Zinc finger protein 142; n=20; Eutheria|Rep:
Zinc finger protein 142 - Homo sapiens (Human)
Length = 1687
Score = 37.5 bits (83), Expect = 0.26
Identities = 24/50 (48%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Frame = -3
Query: 239 QSNRR--RVGRQPHCCLACCDSTTRTYRTRAPKSRSSG-RRLPASSRICP 99
Q +RR G +PH C C STTR YR A +SR +G R+P SS CP
Sbjct: 1187 QQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS--CP 1234
>UniRef50_Q4SPQ5 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
SCAF14537, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 936
Score = 37.1 bits (82), Expect = 0.34
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 12/139 (8%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWARE-FDMYVSYCRNKPDSNAA 211
+F NI ++ ++ F L E + + + + A+ FD Y++YC N+
Sbjct: 546 LFSNISDVCEASQKFFKELEERHQQSIVIDSISDIVCKRAQSSFDPYITYCSNEVYQQRT 605
Query: 212 VVQHAG-----DYFERVQRKKKLEH-PLAAYLIKPVQRITKYQLLLKDLQACCAEGQG-- 367
+ + D R++ + P+ ++LI P+QRIT+ LL+ + +
Sbjct: 606 LQKLVSKKPFKDVLTRIEAHPDCRNLPMISFLILPMQRITRLPLLMDTICQKTPKDSAQY 665
Query: 368 -EIKDGLEVMLSVPKKAND 421
E K L+ + V +K N+
Sbjct: 666 EECKKALQAVSKVVRKCNE 684
>UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep:
CG33519-PB - Drosophila melanogaster (Fruit fly)
Length = 4129
Score = 37.1 bits (82), Expect = 0.34
Identities = 28/79 (35%), Positives = 37/79 (46%)
Frame = +2
Query: 251 RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKANDAMH 430
R + HP L P KY L LK E +++ LE+MLSVP +A D
Sbjct: 127 RTPQAPHPANKRL--PAADFIKYSLSLK-------ENVKDLERALELMLSVPSRAYDNRF 177
Query: 431 LSLLEGCDVPTDSLGEVVL 487
LS +EGC LG ++L
Sbjct: 178 LSSIEGCRGNIYKLGRLLL 196
>UniRef50_Q4P5Y6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 2184
Score = 37.1 bits (82), Expect = 0.34
Identities = 18/49 (36%), Positives = 31/49 (63%)
Frame = +2
Query: 275 LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKAND 421
L++ LIKPVQR+ KY LLLK++ A + +I++ + + K A++
Sbjct: 1536 LSSLLIKPVQRVLKYPLLLKEILASTSHKHPDIENLSAASVEIQKVADN 1584
>UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep:
Intersectin-1 - Homo sapiens (Human)
Length = 1721
Score = 37.1 bits (82), Expect = 0.34
Identities = 23/85 (27%), Positives = 45/85 (52%), Gaps = 8/85 (9%)
Frame = +2
Query: 110 ETMP-EDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQ---HAGDYFERVQR----KKKL 265
E MP + +G Y+ +C + + A + Q A D+ E V+R +
Sbjct: 1308 EKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCK 1367
Query: 266 EHPLAAYLIKPVQRITKYQLLLKDL 340
PL+++++KP+QR+T+Y L++K++
Sbjct: 1368 GMPLSSFILKPMQRVTRYPLIIKNI 1392
>UniRef50_UPI0000DB6CE7 Cluster: PREDICTED: similar to Guanine
nucleotide exchange factor GEF64C CG32239-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Guanine nucleotide
exchange factor GEF64C CG32239-PA - Apis mellifera
Length = 1726
Score = 36.7 bits (81), Expect = 0.45
Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 10/139 (7%)
Frame = +2
Query: 86 FLRELDKYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAV--VQHAGDYFERVQRKK 259
F +E + + DVG F+ R + SYC + ++ + ++ + +
Sbjct: 1398 FAQESGDEDLLTVDVGKIFLESERMLHAFESYCTRQGSASLLLQNLEKEKELLRIFLKVS 1457
Query: 260 KLEHP------LAAYLIKPVQRITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKAND 421
++E+ L ++L+ PVQR+TKY LLL L + +I++ E + +AN
Sbjct: 1458 QMENTVLRRMNLNSFLMVPVQRVTKYPLLLARLLKATPSVRPDIQEAKERLKQA--QANI 1515
Query: 422 AMHLSLL--EGCDVPTDSL 472
+HL + E DV + L
Sbjct: 1516 ELHLEHMNAEAKDVTSTKL 1534
>UniRef50_UPI0000499563 Cluster: 158792 GrfA protein; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: 158792 GrfA protein -
Entamoeba histolytica HM-1:IMSS
Length = 1012
Score = 36.7 bits (81), Expect = 0.45
Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Frame = +2
Query: 104 KYETMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAAVVQHAGD-----YFERVQRKKKLE 268
K T + VG F+ ++ F +Y ++ N + + + D Y E Q +
Sbjct: 446 KNNTFEDSVGELFLKFSPFFIVYRNFLINHNKAFTLLTKLEEDTKLERYLESCQTQFNTN 505
Query: 269 H--PLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE---IKDGLEVMLSVPKKANDAM 427
L YLI PVQR+ +Y LLL DL + I LE M V K N+++
Sbjct: 506 QNLDLRDYLIMPVQRLPRYSLLLTDLLKHTPTNHCDYQNITKALEAMKEVTTKVNESI 563
>UniRef50_UPI0000498C1F Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 555
Score = 36.7 bits (81), Expect = 0.45
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 263 LEHPLAAYLIKPVQRITKYQLLLKDLQ 343
++H L ++LI PVQR+ +Y LLLK+LQ
Sbjct: 141 IKHDLRSFLIMPVQRLPRYVLLLKELQ 167
>UniRef50_Q4RG84 Cluster: Chromosome 2 SCAF15106, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2
SCAF15106, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1410
Score = 36.7 bits (81), Expect = 0.45
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 15/143 (10%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPEDVGHCFVTWAREFD-MYVSYCRNKPDS--- 202
D +FGNI + +R+ LD + + +G F+ + E + +Y YC+N D+
Sbjct: 625 DGLFGNIGSVIDLSQRL----LDALQET-DFIGKTFLDFKAELEEVYKIYCQNHDDAISL 679
Query: 203 ------NAAVVQHAGDYFERVQRK-----KKLEHPLAAYLIKPVQRITKYQLLLKDLQAC 349
++ +H ER++ K L ++LIKPVQR+ +Y LLL +L
Sbjct: 680 LESYEKEESIQRHVLQCLERLRAMYREWGKTNYINLGSFLIKPVQRVMRYPLLLMELLGA 739
Query: 350 CAEGQGEIKDGLEVMLSVPKKAN 418
E + + L L K+ N
Sbjct: 740 TPESHPD-RPELTKALQAVKEIN 761
>UniRef50_Q54SR5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 481
Score = 36.7 bits (81), Expect = 0.45
Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 3/65 (4%)
Frame = +2
Query: 251 RKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACCAEGQGE---IKDGLEVMLSVPKKAND 421
R +KL+ L +YLI+PVQRIT+Y +LL+++ + + + + +M V AN+
Sbjct: 195 RTRKLD--LRSYLIQPVQRITRYHMLLEEVLKHTDQSHTDYPPLTESYRLMKQVTSDANE 252
Query: 422 AMHLS 436
A+ S
Sbjct: 253 AIKKS 257
>UniRef50_A7SRN5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1253
Score = 36.7 bits (81), Expect = 0.45
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Frame = +2
Query: 236 FERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDLQACC---AEGQGEIKDGLEVMLSVP 406
++ + +K PL A+L+KP QR+ Y+ LL+ L C +E +I+ LE ++
Sbjct: 822 YKEFETQKICYLPLNAFLLKPSQRLLHYRFLLERLLKYCVRDSEDSQDIQGALEELVGAV 881
Query: 407 KKANDAM 427
K ++M
Sbjct: 882 KSTEESM 888
>UniRef50_Q5VV41 Cluster: Rho guanine nucleotide exchange factor 16;
n=24; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 16 - Homo sapiens (Human)
Length = 709
Score = 36.7 bits (81), Expect = 0.45
Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVF--LRELDKYETMPEDVGHCFVTWA-REFDMYVSYCRNKPDSNAA 211
+F NI ++ +R F L + K + + ED+ A + F Y++YC N+
Sbjct: 328 LFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRT 387
Query: 212 VVQHAGDYFERVQRKKKLEH-------PLAAYLIKPVQRITKYQLLLKDLQACCAEGQG 367
+ + + +++E P+ ++LI P+QR+T+ LL+ L C + QG
Sbjct: 388 LQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTL---CLKTQG 443
>UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB;
n=2; Tribolium castaneum|Rep: PREDICTED: similar to
CG33519-PB - Tribolium castaneum
Length = 4089
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/59 (33%), Positives = 29/59 (49%)
Frame = +2
Query: 308 ITKYQLLLKDLQACCAEGQGEIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVV 484
I Y + L AC E +++ LE+MLSVP +A D S +EG LG ++
Sbjct: 18 ILYYIIELVRYSACLGEDNSDLQKALELMLSVPHRAQDEKFTSNIEGYRGSIHKLGRLL 76
>UniRef50_UPI00006CB721 Cluster: RhoGEF domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: RhoGEF domain
containing protein - Tetrahymena thermophila SB210
Length = 1093
Score = 36.3 bits (80), Expect = 0.60
Identities = 28/112 (25%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Frame = +2
Query: 20 LQGKEDL--IFGNIEEIHRFHERV--FLREL-DKYETMPEDVGHCFVTWAREFDMYVSYC 184
L ++D+ IF NI++I ++ +++E+ DKY + +V + + F++ + Y
Sbjct: 100 LNNEQDIQKIFSNIQQILELNQDFLEYIKEVFDKYIQVTIPYFKIYVDYMQNFEVSMQYL 159
Query: 185 RNKPDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
+ + DY ++ + + +++ LI PVQRI +Y+LL K L
Sbjct: 160 EKLKEGRKDI----RDYLKQFESEND---NISSLLILPVQRIPRYELLFKTL 204
>UniRef50_Q54YZ6 Cluster: RhoGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RhoGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 1218
Score = 36.3 bits (80), Expect = 0.60
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Frame = +2
Query: 11 PLPLQGKEDLIFGNIEEIHRFHERVFLRELDKYETMPED--VGHCFVTWAREFDMYVSYC 184
P+ Q + IF + I +++R+ + + + D +G F+ ++ +Y Y
Sbjct: 811 PIISQEEVQSIFSEVSIILSYNKRLLIDLEGRTKDWKVDTLIGDIFIKFSNFLKIYSQYS 870
Query: 185 RNKPDSNAAVVQ-----HAGDYFERVQRKKK--LEHPLAAYLIKPVQRITKYQLLLKDL 340
R+ ++ + + Y +V+ + L YLI+P+QRI +Y LL+KD+
Sbjct: 871 RSYSEAMGVLNECKKQTKFKSYLNKVKESNEEIKLRGLEDYLIRPIQRIPRYSLLIKDM 929
>UniRef50_Q54PK2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1170
Score = 36.3 bits (80), Expect = 0.60
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Frame = +2
Query: 140 FVTWAREFDMYVSYCRNKPDSNAAVVQHAGD---YFERVQRKKKLEH-PLAAYLIKPVQR 307
FV+ A Y YC N+ + + G Y + +++ P ++LIKPVQR
Sbjct: 809 FVSMADFLKSYFVYCSNQQKALSTFSALKGKNCTYLAYLLTRRECRSLPFDSFLIKPVQR 868
Query: 308 ITKYQLLLKDL 340
+ KY LL+++L
Sbjct: 869 VCKYPLLIREL 879
>UniRef50_Q54C56 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1076
Score = 36.3 bits (80), Expect = 0.60
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLREL----DKYETMPEDVGHCFVTW------AREFDMYVSYC 184
+ IF NI+++ R FL++L DK + + ++ HC + E Y++
Sbjct: 672 ETIFSNIDKVFRVSCE-FLKKLRGMSDKKDVL--ELAHCLQWYWDQKDTIEELRTYINNF 728
Query: 185 RNKPD---SNAAVVQHAGDYFERVQRKKKLE-HPLAAYLIKPVQRITKYQLLLKDL 340
D N A + ++ E+ Q ++ + + +YLI+PVQR+ +Y LLL DL
Sbjct: 729 NKAMDCVHENRAKLPKFKEFLEKCQFSEQCKSETIDSYLIRPVQRVPRYILLLTDL 784
>UniRef50_Q21653 Cluster: Uncharacterized protein R02F2.2; n=1;
Caenorhabditis elegans|Rep: Uncharacterized protein
R02F2.2 - Caenorhabditis elegans
Length = 1182
Score = 36.3 bits (80), Expect = 0.60
Identities = 28/112 (25%), Positives = 56/112 (50%), Gaps = 10/112 (8%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFL---RELDKY--ETMPEDVGHCFVTWAREFDMYVSYCRNKPD 199
D IF I EI H+ + + +D++ + + DV + + Y+S+ N
Sbjct: 402 DKIFYRIPEILAHHQVLLTTLSQRIDQWHKDAILGDVLLAHFSKQSMIETYISFVDNFKF 461
Query: 200 SNAAVVQHAGDY-FERVQRKKKLEHP----LAAYLIKPVQRITKYQLLLKDL 340
+ A+++Q + FE+ + +HP L + LI P+QR+ +Y+L++K +
Sbjct: 462 AKASIIQARQKHAFEKYYNRCCRDHPNKLDLDSLLISPIQRVPRYELIVKQM 513
>UniRef50_UPI0000F1F644 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 841
Score = 35.9 bits (79), Expect = 0.79
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Frame = +2
Query: 41 IFGNIEEIHRFHERVFLRELDKYE---TMPEDVGHCFVTWAREFDMYVSYCRNKPDSNAA 211
IF NI I+ FH + L +L+K T +G MY Y RN +
Sbjct: 316 IFSNITSINAFHSQFLLPDLEKRMGEWTSTPRIGDILQKLTPFLKMYAEYVRNFDHAMDL 375
Query: 212 VVQ--HAGDYFERV----QRKKKLEH-PLAAYLIKPVQRITKYQLLLKD 337
+ Q F+ + Q ++ + L ++++PVQR+ +Y++LLKD
Sbjct: 376 LKQWIDRSPPFKAIILDIQSQEVCGNLTLQHHMLEPVQRVPRYEMLLKD 424
>UniRef50_UPI000051A1F0 Cluster: PREDICTED: similar to CG3799-PA,
isoform A isoform 1; n=1; Apis mellifera|Rep: PREDICTED:
similar to CG3799-PA, isoform A isoform 1 - Apis
mellifera
Length = 773
Score = 35.9 bits (79), Expect = 0.79
Identities = 30/112 (26%), Positives = 61/112 (54%), Gaps = 12/112 (10%)
Frame = +2
Query: 29 KEDLIFGNIEEIHRFHERVFLRELD---KYETMPEDVGHCFVTWA-REFDMYVSYCRNKP 196
++D IFG+I + + E+ FL EL+ + + M D+ + + +A R D+YV+YC N+
Sbjct: 372 EKDKIFGDIPSVLQASEQ-FLAELETVWRQDPMLHDLPNVLLKYADRCLDIYVTYCSNQV 430
Query: 197 DSNAAV----VQHAGDYFE---RVQRKKKLEH-PLAAYLIKPVQRITKYQLL 328
+ + + + E +++ + ++ L ++L+ P+QRIT+ LL
Sbjct: 431 SIDTTLRDLRTRKGLKFLETISQIEARSTCQNLSLHSFLMLPMQRITRLPLL 482
>UniRef50_UPI000049944B Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 835
Score = 35.9 bits (79), Expect = 0.79
Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 8/110 (7%)
Frame = +2
Query: 35 DLIFGNIEEIHRFHERVFLRELDKYETMPE-------DVGHCFVTWAREFDMYVSYCRNK 193
D +F N ++++ H R+F + +++ + E D+ F W +D Y Y
Sbjct: 565 DTLFSNFKDVYEIHTRLFKKISERWLSQKEEAFVSIADIFIDFFNWKEVYDAYARYLVEA 624
Query: 194 PDSNAAVVQHAGDYF-ERVQRKKKLEHPLAAYLIKPVQRITKYQLLLKDL 340
D +++ LA +LI PVQR+ +Y LLL+ L
Sbjct: 625 DDGIQFDFSEKPKIIKDQLTTWAGQCLILANFLILPVQRLPRYVLLLESL 674
>UniRef50_A7CXR3 Cluster: ABC transporter related; n=1; Opitutaceae
bacterium TAV2|Rep: ABC transporter related -
Opitutaceae bacterium TAV2
Length = 615
Score = 35.9 bits (79), Expect = 0.79
Identities = 34/113 (30%), Positives = 48/113 (42%), Gaps = 11/113 (9%)
Frame = +2
Query: 194 PDSNAAVVQHAGDYFERVQRKKKLEHPLAAYLIKP----VQRITKYQLLLKDLQACCAEG 361
P A +V H GD R + + PL + P +RITK+ ++KD AEG
Sbjct: 290 PSRRARLVPHRGDEIHRGKTRPLARRPLTRPPVFPPMIEARRITKFFSVVKDDGT--AEG 347
Query: 362 QG-------EIKDGLEVMLSVPKKANDAMHLSLLEGCDVPTDSLGEVVLQGLL 499
+I DG V + P + L +L G PT+ GEV + G L
Sbjct: 348 ATAVLSVSLKINDGAFVAIVGPTGCGKSTFLEILAGLQAPTE--GEVFIDGRL 398
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 672,027,590
Number of Sequences: 1657284
Number of extensions: 13984012
Number of successful extensions: 49059
Number of sequences better than 10.0: 345
Number of HSP's better than 10.0 without gapping: 46678
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 48872
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45636850930
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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