Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--2185
(735 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B6235 Cluster: PREDICTED: similar to ENSANGP000... 346 4e-94
UniRef50_Q9W0S9 Cluster: Disco-interacting protein 2; n=16; Eume... 317 2e-85
UniRef50_Q1RS87 Cluster: Putative uncharacterized protein; n=2; ... 270 2e-71
UniRef50_Q4RQQ3 Cluster: Chromosome 2 SCAF15004, whole genome sh... 265 7e-70
UniRef50_Q4SU65 Cluster: Chromosome undetermined SCAF14007, whol... 259 6e-68
UniRef50_Q4SL77 Cluster: Chromosome undetermined SCAF14561, whol... 259 6e-68
UniRef50_Q4T6E9 Cluster: Chromosome undetermined SCAF8797, whole... 256 3e-67
UniRef50_Q14689 Cluster: Disco-interacting protein 2 homolog A; ... 253 3e-66
UniRef50_Q4SKU1 Cluster: Chromosome undetermined SCAF14565, whol... 188 2e-46
UniRef50_Q4RQ07 Cluster: Chromosome 17 SCAF15006, whole genome s... 152 1e-35
UniRef50_UPI0000F1EC39 Cluster: PREDICTED: similar to KIAA0184 p... 60 4e-08
UniRef50_Q4SNK4 Cluster: Chromosome 15 SCAF14542, whole genome s... 60 4e-08
UniRef50_A5NTM2 Cluster: AMP-dependent synthetase and ligase; n=... 60 6e-08
UniRef50_Q21WI4 Cluster: AMP-dependent synthetase and ligase; n=... 58 2e-07
UniRef50_A5MZS3 Cluster: Predicted NRPS adenylation domain; n=1;... 57 4e-07
UniRef50_Q21HW6 Cluster: AMP-dependent synthetase and ligase; n=... 55 2e-06
UniRef50_A3ZQ92 Cluster: Saframycin Mx1 synthetase B; n=1; Blast... 54 5e-06
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 52 2e-05
UniRef50_Q094Z1 Cluster: Beta-ketoacyl synthase; n=1; Stigmatell... 50 4e-05
UniRef50_Q7NJ79 Cluster: Gll1953 protein; n=1; Gloeobacter viola... 50 6e-05
UniRef50_A7GTF8 Cluster: Beta-ketoacyl synthase; n=3; cellular o... 50 6e-05
UniRef50_Q7NJ84 Cluster: Gll1948 protein; n=21; Bacteria|Rep: Gl... 49 1e-04
UniRef50_A5NY43 Cluster: AMP-dependent synthetase and ligase; n=... 49 1e-04
UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 49 1e-04
UniRef50_Q0LNS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 49 1e-04
UniRef50_Q8DTJ2 Cluster: Putative peptide synthetase; n=1; Strep... 48 2e-04
UniRef50_Q5P000 Cluster: CoA ligase, AMP generating; n=2; Betapr... 48 2e-04
UniRef50_Q8YPY3 Cluster: Alr4057 protein; n=5; Cyanobacteria|Rep... 48 2e-04
UniRef50_Q2SG85 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 48 3e-04
UniRef50_Q0M3P0 Cluster: AMP-dependent synthetase and ligase; n=... 47 4e-04
UniRef50_A5IE32 Cluster: Saframycin Mx1 synthetase B; n=4; Legio... 47 4e-04
UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2; S... 46 7e-04
UniRef50_Q0B1F1 Cluster: Beta-ketoacyl synthase; n=1; Burkholder... 46 7e-04
UniRef50_A0PWU0 Cluster: Polyketide synthase Pks16_1; n=1; Mycob... 46 7e-04
UniRef50_UPI0001597892 Cluster: NrsF; n=1; Bacillus amyloliquefa... 45 0.002
UniRef50_Q4BZ64 Cluster: AMP-dependent synthetase and ligase; n=... 45 0.002
UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2; Com... 45 0.002
UniRef50_Q127J0 Cluster: AMP-dependent synthetase and ligase; n=... 45 0.002
UniRef50_A4BLA6 Cluster: Hypothetical acyltransferase family pro... 45 0.002
UniRef50_Q82U49 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.003
UniRef50_Q096N9 Cluster: Beta-ketoacyl synthase; n=1; Stigmatell... 44 0.004
UniRef50_Q9LW70 Cluster: Long-chain-fatty-acid-CoA ligase-like p... 44 0.004
UniRef50_Q83AH1 Cluster: Acyltransferase family protein; n=4; Co... 43 0.007
UniRef50_Q3DZ13 Cluster: AMP-dependent synthetase and ligase; n=... 43 0.009
UniRef50_Q08ST3 Cluster: Saframycin Mx1 synthetase B; n=1; Stigm... 43 0.009
UniRef50_Q113H9 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.016
UniRef50_A7HI15 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.016
UniRef50_Q7UYT8 Cluster: Saframycin Mx1 synthetase B; n=2; Bacte... 41 0.036
UniRef50_A3YGJ3 Cluster: Beta-ketoacyl synthase; n=1; Marinomona... 41 0.036
UniRef50_UPI000011F913 Cluster: UPI000011F913 related cluster; n... 40 0.048
UniRef50_Q0C1U0 Cluster: Putative AMP binding protein; n=1; Hyph... 40 0.048
UniRef50_Q2JBN8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.084
UniRef50_Q06YY4 Cluster: Acyl-CoA ligase/dehydrogenase fusion pr... 40 0.084
UniRef50_A5UV23 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.084
UniRef50_Q0LUE8 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.11
UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1; ... 39 0.15
UniRef50_Q3JM63 Cluster: Peptide synthetase NRPS5-4-3; n=16; Bur... 39 0.15
UniRef50_Q6H901 Cluster: Putative odorant-binding protein OBPjj1... 38 0.19
UniRef50_A6E4W0 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 38 0.34
UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosip... 37 0.45
UniRef50_A3ILP8 Cluster: Beta-ketoacyl synthase; n=1; Cyanothece... 37 0.45
UniRef50_Q0SK67 Cluster: Probable non-ribosomal peptide syntheta... 37 0.59
UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 37 0.59
UniRef50_Q1JTE1 Cluster: Type I fatty acid synthase, putative; n... 37 0.59
UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA... 36 0.78
UniRef50_A1WAC9 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.78
UniRef50_Q2UQJ0 Cluster: Predicted AMP-binding protein; n=6; Pez... 36 0.78
UniRef50_A1YBQ9 Cluster: AmbG; n=1; Sorangium cellulosum|Rep: Am... 36 1.0
UniRef50_UPI00005579A6 Cluster: COG0318: Acyl-CoA synthetases (A... 36 1.4
UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1; S... 36 1.4
UniRef50_Q666G1 Cluster: Possible high molecular weight sideroph... 35 1.8
UniRef50_Q1PSF3 Cluster: Vlm2; n=1; Streptomyces tsusimaensis|Re... 35 1.8
UniRef50_Q01CP6 Cluster: Acyl-CoA synthetase; n=6; Eukaryota|Rep... 35 1.8
UniRef50_Q5ZXY3 Cluster: 2-acylglycerophosphoethanolamine acyltr... 35 2.4
UniRef50_UPI000155D219 Cluster: PREDICTED: similar to signaling ... 34 3.1
UniRef50_UPI0000F2C306 Cluster: PREDICTED: hypothetical protein;... 34 3.1
UniRef50_Q9A929 Cluster: Acyl-CoA synthetase; n=4; Alphaproteoba... 34 3.1
UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces... 34 3.1
UniRef50_Q3W6N9 Cluster: AMP-dependent synthetase and ligase; n=... 34 3.1
UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for vi... 34 3.1
UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide syntheta... 34 3.1
UniRef50_UPI0000E48CA6 Cluster: PREDICTED: similar to gp330 prec... 34 4.2
UniRef50_Q28S28 Cluster: AMP-dependent synthetase and ligase; n=... 34 4.2
UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1; Xan... 34 4.2
UniRef50_Q7UGQ5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q5H0R0 Cluster: Predicted GTPases; n=1; Xanthomonas ory... 33 5.5
UniRef50_Q47Q23 Cluster: Putative ortho-succinylbenzoate-CoA syn... 33 5.5
UniRef50_Q09164 Cluster: Cyclosporine synthetase; n=8; Fungi/Met... 33 5.5
UniRef50_UPI0000E24D6A Cluster: PREDICTED: hypothetical protein;... 33 7.3
UniRef50_Q62F82 Cluster: AMP-binding domain protein; n=15; Burkh... 33 7.3
UniRef50_O67872 Cluster: Acetyl-coenzyme A synthetase; n=5; cell... 33 7.3
UniRef50_Q5JL80 Cluster: Putative uncharacterized protein OSJNBa... 33 7.3
UniRef50_Q0CC85 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_A1D1R6 Cluster: AMP binding domain protein, putative; n... 33 7.3
UniRef50_Q5FTV0 Cluster: Acetyl-coenzyme A synthetase; n=1; Gluc... 33 9.6
UniRef50_Q212V5 Cluster: Amino acid adenylation; n=2; cellular o... 33 9.6
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 9.6
>UniRef50_UPI00015B6235 Cluster: PREDICTED: similar to
ENSANGP00000025395; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000025395 - Nasonia
vitripennis
Length = 2263
Score = 346 bits (850), Expect = 4e-94
Identities = 154/213 (72%), Positives = 181/213 (84%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTEKLXXXXXXXXXXXX 180
+GFLLGSCGIQ ALTS+ACLKGLPKT++G+V++F+GWP LHW TE L
Sbjct: 1093 IGFLLGSCGIQVALTSEACLKGLPKTAAGEVIAFKGWPKLHWFVTEHLGKTPKDWMPPTR 1152
Query: 181 XADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGL 360
D+ PA+IE+T+ DGS MGV VTRA+MLAHCR L+ AC YTEGE+ VCVLDFKRE GL
Sbjct: 1153 LTDDTPAYIEYTTDRDGSVMGVTVTRAAMLAHCRALTQACGYTEGENAVCVLDFKREVGL 1212
Query: 361 WHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKE 540
WH+ L S+LNGMHVIFIPYALMKV+PASWM MITKHRAS+A+VKSRDLHWGLLAT+DHK+
Sbjct: 1213 WHSTLTSILNGMHVIFIPYALMKVNPASWMQMITKHRASVAVVKSRDLHWGLLATKDHKD 1272
Query: 541 ISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
ISLS+LR+LLVADGANPWSLSSCDQFLSVF+++
Sbjct: 1273 ISLSTLRLLLVADGANPWSLSSCDQFLSVFQSK 1305
Score = 56.8 bits (131), Expect = 5e-07
Identities = 34/144 (23%), Positives = 67/144 (46%)
Frame = +1
Query: 40 LTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTS 219
LT+ LK L + +VV + WP++ + + + A E A+++ +
Sbjct: 1767 LTNQTILKLLKSKEANNVVEVKSWPTI--LDMDDMPKKKLPVLYRAPTA-EMLAYLDFSV 1823
Query: 220 AADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMH 399
+ G G+ ++ A++ + CR + +AC H+ LD G L+S+ +G H
Sbjct: 1824 STTGMLAGIKMSHAAVTSLCRAMKLACELYPSRHIALCLDPYSGLGFALWCLSSIYSGHH 1883
Query: 400 VIFIPYALMKVSPASWMHMITKHR 471
I IP + ++ +PA W+ ++ R
Sbjct: 1884 SILIPPSEVEANPALWLSAVSHSR 1907
Score = 47.2 bits (107), Expect = 4e-04
Identities = 19/28 (67%), Positives = 24/28 (85%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRRAG 713
QSKG+R DA+CPCA SSE++TV +RR G
Sbjct: 1303 QSKGLRPDAVCPCASSSEALTVSVRRPG 1330
>UniRef50_Q9W0S9 Cluster: Disco-interacting protein 2; n=16;
Eumetazoa|Rep: Disco-interacting protein 2 - Drosophila
melanogaster (Fruit fly)
Length = 1773
Score = 317 bits (779), Expect = 2e-85
Identities = 148/215 (68%), Positives = 174/215 (80%), Gaps = 2/215 (0%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPK-TSSGDVVSFRGWPSLHWVSTEKLXXXXXXXXXXX 177
VGFLL SCGI ALTS+ACLKGLPK T++G++ +GWP L W TE L
Sbjct: 558 VGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGN 617
Query: 178 XXADE-CPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRET 354
AD+ A+IE+T+ +GS MGV VTRA+M+ HCR L++AC+YTEGE +VCVLDFKRE
Sbjct: 618 LRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREV 677
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH 534
GLWH+VL SVLNGMHVIFIPYALMK+ P+SWM +ITKHRAS +VKSRDLHWGLLAT+DH
Sbjct: 678 GLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDH 737
Query: 535 KEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
K+ISLSSLRMLLVADGANPWSLSSCDQFLSVF+A+
Sbjct: 738 KDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAK 772
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/91 (26%), Positives = 43/91 (47%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A+++ + + G GV +T S+ + C L +AC H+ LD G L
Sbjct: 1300 AYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLI 1359
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHR 471
V +G H I I ++ +P+ W+ +++HR
Sbjct: 1360 GVYSGHHSILIAPYEVEANPSLWLSTLSQHR 1390
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/28 (67%), Positives = 22/28 (78%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRRAG 713
Q+KG+R DAICPCA SSE TV +RR G
Sbjct: 770 QAKGLRSDAICPCASSSEVFTVSLRRPG 797
>UniRef50_Q1RS87 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1539
Score = 270 bits (662), Expect = 2e-71
Identities = 127/228 (55%), Positives = 161/228 (70%), Gaps = 18/228 (7%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKT------------------SSGDVVSFRGWPSLHW 126
+GFLLG+CG++ ALTS++C KGLPK +S ++V FRGWP L W
Sbjct: 381 LGFLLGNCGVKVALTSESCYKGLPKKVNTSSTFSAPSGSNSLTGTSSEIVDFRGWPRLWW 440
Query: 127 VSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNY 306
TE + ADE A+IE+T+ DG+ G VTR ++ AHCR L+ A Y
Sbjct: 441 AVTEHMSKPSRDWTAPPRLADETIAYIEYTTGNDGTVKGCCVTRQAVFAHCRALTTAMEY 500
Query: 307 TEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAI 486
E E MVCV+DFKRE GLWHA+LAS+ NGM VIF+PY+LMK++PA+WMHM++K++A+ A+
Sbjct: 501 KEDETMVCVVDFKREVGLWHAILASIFNGMKVIFVPYSLMKMNPATWMHMVSKYQATTAL 560
Query: 487 VKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
VKSRDLHW LLATRDHK+ISL+SLR LLVADGANPWSLSSCD F + F
Sbjct: 561 VKSRDLHWALLATRDHKDISLASLRTLLVADGANPWSLSSCDAFAAAF 608
Score = 35.5 bits (78), Expect = 1.4
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +3
Query: 642 VRGDAICPCACSSESMTVCIRRAG 713
+R DA+CPCA SSE+ T+ IRR G
Sbjct: 615 LRPDAMCPCAGSSETGTISIRRRG 638
>UniRef50_Q4RQQ3 Cluster: Chromosome 2 SCAF15004, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2
SCAF15004, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1556
Score = 265 bits (650), Expect = 7e-70
Identities = 121/215 (56%), Positives = 156/215 (72%), Gaps = 2/215 (0%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTE--KLXXXXXXXXXX 174
+GFLLGSCG+ ALT+DAC KGLPK +G+V +F+GWP L W T+ +
Sbjct: 493 IGFLLGSCGVTLALTTDACQKGLPKAQTGEVATFKGWPRLLWFVTDGKHVVKPPKDWHPP 552
Query: 175 XXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRET 354
A A+IE+ ++ +GS MGV V+ ++ML HC L+ AC YTEGE + VLDFKRE
Sbjct: 553 VREASNDVAYIEYKTSKEGSTMGVTVSHSAMLTHCHTLTQACGYTEGETITNVLDFKREA 612
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH 534
GLWH VL SV+N MHVI IPY+LMKV+P SW+ + ++A +A+VKSRD+HW LLA RD
Sbjct: 613 GLWHGVLTSVMNRMHVISIPYSLMKVNPLSWIQKVHLYKARVAVVKSRDMHWSLLAQRDQ 672
Query: 535 KEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
++ISL SLRML+VADGANPWS+SSCD FL+VF+AR
Sbjct: 673 RDISLGSLRMLIVADGANPWSISSCDAFLNVFQAR 707
Score = 43.2 bits (97), Expect = 0.007
Identities = 18/31 (58%), Positives = 24/31 (77%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRRAGPVD 722
Q++G+R + ICPCA SSE+MTV IRR +D
Sbjct: 705 QARGLRPEVICPCASSSEAMTVAIRRPPEMD 735
>UniRef50_Q4SU65 Cluster: Chromosome undetermined SCAF14007, whole
genome shotgun sequence; n=2; Clupeocephala|Rep:
Chromosome undetermined SCAF14007, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1449
Score = 259 bits (634), Expect = 6e-68
Identities = 115/215 (53%), Positives = 158/215 (73%), Gaps = 2/215 (0%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTEK--LXXXXXXXXXX 174
+GFLLGSC + ALTSDAC KGLPK+ +G++ FRGWP + W TE L
Sbjct: 439 IGFLLGSCEVTVALTSDACQKGLPKSPTGEIPQFRGWPKVLWFVTESKHLSKPPRDWFPH 498
Query: 175 XXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRET 354
A+ A+IE+ + DGS +GV VTR +ML HC+ L+ +C+YTE E +V VLDFK++
Sbjct: 499 IKDANRDTAYIEYKTCKDGSVLGVTVTRIAMLTHCQALTQSCSYTEAETIVNVLDFKKDV 558
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH 534
GLWHAV SV+N +H+I +PYALMKV+P SW+ + +++A +A VKSRD+HW L+A RD
Sbjct: 559 GLWHAVQTSVMNMLHIISVPYALMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQ 618
Query: 535 KEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
++++LSSLRMLLVADG+NPWS+SSCD FL+VF+++
Sbjct: 619 RDVNLSSLRMLLVADGSNPWSISSCDAFLNVFQSK 653
Score = 41.9 bits (94), Expect = 0.016
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
QSKG+R + ICPCA S E++TV IRR
Sbjct: 651 QSKGLRSEVICPCASSPEALTVAIRR 676
>UniRef50_Q4SL77 Cluster: Chromosome undetermined SCAF14561, whole
genome shotgun sequence; n=6; Euteleostomi|Rep:
Chromosome undetermined SCAF14561, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1291
Score = 259 bits (634), Expect = 6e-68
Identities = 115/215 (53%), Positives = 158/215 (73%), Gaps = 2/215 (0%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTEK--LXXXXXXXXXX 174
+GFLLGSC + ALTSDAC KGLPK+ +G++ FRGWP + W TE L
Sbjct: 160 IGFLLGSCEVTVALTSDACQKGLPKSPTGEIPQFRGWPKVLWFVTESKHLSKPPRDWFPH 219
Query: 175 XXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRET 354
A+ A+IE+ + DGS +GV VTR +ML HC+ L+ +C+YTE E +V VLDFK++
Sbjct: 220 IKDANRDTAYIEYKTCKDGSVLGVTVTRIAMLTHCQALTQSCSYTEAETIVNVLDFKKDV 279
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH 534
GLWHAV SV+N +H+I +PYALMKV+P SW+ + +++A +A VKSRD+HW L+A RD
Sbjct: 280 GLWHAVQTSVMNMLHIISVPYALMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQ 339
Query: 535 KEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
++++LSSLRMLLVADG+NPWS+SSCD FL+VF+++
Sbjct: 340 RDVNLSSLRMLLVADGSNPWSISSCDAFLNVFQSK 374
Score = 41.9 bits (94), Expect = 0.016
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
QSKG+R + ICPCA S E++TV IRR
Sbjct: 372 QSKGLRSEVICPCASSPEALTVAIRR 397
>UniRef50_Q4T6E9 Cluster: Chromosome undetermined SCAF8797, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF8797,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1253
Score = 256 bits (628), Expect = 3e-67
Identities = 114/215 (53%), Positives = 158/215 (73%), Gaps = 2/215 (0%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTEK--LXXXXXXXXXX 174
+GFLLGSCG+ ALTSDAC KGLPK+++G++ F+GWP L W TE L
Sbjct: 353 IGFLLGSCGVTVALTSDACHKGLPKSATGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPH 412
Query: 175 XXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRET 354
A+ A+IE+ + GS +GV VTR ++L HC+ L+ +C+YTE E +V VLDFK++
Sbjct: 413 IKDANNDTAYIEYKTCKTGSVLGVTVTRIALLTHCQALTQSCSYTEAETVVNVLDFKKDV 472
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH 534
GLW+ +L SV+N MHVI +PY+LMKV+P SW+ + +++A +A VKSRD+HW L+A +D
Sbjct: 473 GLWNGILTSVMNMMHVISVPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHKDQ 532
Query: 535 KEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
K+I+LSSLRMLLVADG+NPWS+SSCD FL+VF+ +
Sbjct: 533 KDINLSSLRMLLVADGSNPWSISSCDAFLNVFQTK 567
Score = 42.3 bits (95), Expect = 0.012
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
Q+KG+R D ICPCA S E++TV IRR
Sbjct: 565 QTKGLRADVICPCASSPEALTVAIRR 590
>UniRef50_Q14689 Cluster: Disco-interacting protein 2 homolog A;
n=116; Coelomata|Rep: Disco-interacting protein 2 homolog
A - Homo sapiens (Human)
Length = 1571
Score = 253 bits (620), Expect = 3e-66
Identities = 115/215 (53%), Positives = 153/215 (71%), Gaps = 2/215 (0%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHW--VSTEKLXXXXXXXXXX 174
VGFLLGSCG+ ALT+DAC KGLPK +G+V +F+GWP L W + + L
Sbjct: 442 VGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPL 501
Query: 175 XXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRET 354
A+IE+ ++ +GS +GV V+ AS+LA CR L+ AC Y+E E + VLDFKR+
Sbjct: 502 AQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDA 561
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH 534
GLWH VL SV+N MHV+ +PYALMK +P SW+ + ++A A+VKSRD+HW LLA R
Sbjct: 562 GLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ 621
Query: 535 KEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
+++SLSSLRML+VADGANPWS+SSCD FL+VF++R
Sbjct: 622 RDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 656
Score = 39.9 bits (89), Expect = 0.063
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
QS+G+R + ICPCA S E++TV IRR
Sbjct: 654 QSRGLRPEVICPCASSPEALTVAIRR 679
>UniRef50_Q4SKU1 Cluster: Chromosome undetermined SCAF14565, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14565, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1584
Score = 188 bits (457), Expect = 2e-46
Identities = 102/242 (42%), Positives = 146/242 (60%), Gaps = 29/242 (11%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRGWPSLHWVSTEK--LXXXXXXXXXX 174
+GFLLGSCG+ ALTSDAC KGLPK+++G++ F+GWP L W TE L
Sbjct: 422 IGFLLGSCGVTVALTSDACHKGLPKSATGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPH 481
Query: 175 XXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA------------------- 297
A+ A+IE+ + DGS +GV VTR ++L HC+ L+ +
Sbjct: 482 IKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQSCSYTEGMRAHTNTHTHTHT 541
Query: 298 -CNYTE-------GEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMH 453
C++ E +V VLDFK++ GLW+ +L SV+N MHVI +PY+LMKV+P SW+
Sbjct: 542 FCSFNSRPLRLSVAETVVNVLDFKKDVGLWNGILTSVMNMMHVISVPYSLMKVNPLSWIQ 601
Query: 454 MITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFK 633
+ +++A +A VKSRD+HW L+A +D K+I+LS L A A S+SSCD FL+VF+
Sbjct: 602 KVCQYKAKVACVKSRDMHWALVAHKDQKDINLS-----LAAHAAG--SISSCDAFLNVFQ 654
Query: 634 AR 639
+
Sbjct: 655 TK 656
Score = 42.3 bits (95), Expect = 0.012
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
Q+KG+R D ICPCA S E++TV IRR
Sbjct: 654 QTKGLRADVICPCASSPEALTVAIRR 679
>UniRef50_Q4RQ07 Cluster: Chromosome 17 SCAF15006, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF15006, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 316
Score = 152 bits (368), Expect = 1e-35
Identities = 64/111 (57%), Positives = 90/111 (81%)
Frame = +1
Query: 307 TEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAI 486
T E +V VLD K++ GLWHAV SV+N +H+I +PYALMKV+P SW+ + +++A +A
Sbjct: 36 TAAETIVNVLDVKKDVGLWHAVQTSVMNMLHIISVPYALMKVNPLSWIQKVCQYKAKVAC 95
Query: 487 VKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFKAR 639
VKSRD+HW +A RD ++++LSSLRMLLVADG+NPWS+SSCD FL+VF+++
Sbjct: 96 VKSRDMHWAPVAHRDQRDVNLSSLRMLLVADGSNPWSISSCDTFLNVFQSK 146
>UniRef50_UPI0000F1EC39 Cluster: PREDICTED: similar to KIAA0184
protein; n=1; Danio rerio|Rep: PREDICTED: similar to
KIAA0184 protein - Danio rerio
Length = 593
Score = 60.5 bits (140), Expect = 4e-08
Identities = 25/36 (69%), Positives = 31/36 (86%)
Frame = +1
Query: 1 VGFLLGSCGIQYALTSDACLKGLPKTSSGDVVSFRG 108
VGFLLGSCG+ ALT+DAC KGLPK +G+VV+F+G
Sbjct: 56 VGFLLGSCGVTLALTTDACQKGLPKAQTGEVVTFKG 91
Score = 41.9 bits (94), Expect = 0.016
Identities = 17/26 (65%), Positives = 22/26 (84%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
QS+G+R + ICPCA SSE++TV IRR
Sbjct: 104 QSRGLRPEVICPCASSSEALTVAIRR 129
>UniRef50_Q4SNK4 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 405
Score = 60.5 bits (140), Expect = 4e-08
Identities = 26/43 (60%), Positives = 35/43 (81%)
Frame = +1
Query: 472 ASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSL 600
A +A V SRD+HW +A RD ++++LSSLRMLLVADG+NP+ L
Sbjct: 1 AKVACVTSRDMHWAPVAHRDQRDVNLSSLRMLLVADGSNPFPL 43
Score = 39.1 bits (87), Expect = 0.11
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +3
Query: 630 QSKGVRGDAICPCACSSESMTVCIRR 707
QSKG+R + CPCA S E++TV IRR
Sbjct: 84 QSKGLRSEVRCPCASSPEALTVAIRR 109
>UniRef50_A5NTM2 Cluster: AMP-dependent synthetase and ligase; n=1;
Methylobacterium sp. 4-46|Rep: AMP-dependent synthetase
and ligase - Methylobacterium sp. 4-46
Length = 958
Score = 60.1 bits (139), Expect = 6e-08
Identities = 39/146 (26%), Positives = 66/146 (45%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A I++TS + G GV +T A++LA+ R + A + + +V L + GL L
Sbjct: 293 ALIQYTSGSTGDPKGVTLTHANLLANVRAMGEALGASSADVVVSWLPLYHDMGLIGCWLG 352
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSL 558
S+ G + +P P SW+ I +HR +I+ + L + RD L
Sbjct: 353 SLYFGAPAVILPPLAFLADPGSWLWAIHRHRGTISAAPNFAYELCLKSLRDEDVAGLDLG 412
Query: 559 RMLLVADGANPWSLSSCDQFLSVFKA 636
+ ++ +GA P S + +F F A
Sbjct: 413 SLRVLTNGAEPVSPDTLARFARRFGA 438
>UniRef50_Q21WI4 Cluster: AMP-dependent synthetase and ligase; n=1;
Rhodoferax ferrireducens T118|Rep: AMP-dependent
synthetase and ligase - Rhodoferax ferrireducens (strain
DSM 15236 / ATCC BAA-621 / T118)
Length = 958
Score = 58.4 bits (135), Expect = 2e-07
Identities = 37/144 (25%), Positives = 65/144 (45%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + G GVI+T A++LA+ R + A + V L + GL A L
Sbjct: 300 AFLQYTSGSTGDPKGVILTHANLLANLRAMWRASQVGSSDTFVSWLPLYHDMGLIGACLG 359
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSL 558
++ G H++ + PA W+ I +HR +++ + L D + L
Sbjct: 360 ALYLGFHLVLMSPLAFLARPARWLETIHRHRGTVSAAPNFAYELCLSKLTDAELAGLDLS 419
Query: 559 RMLLVADGANPWSLSSCDQFLSVF 630
L +GA P S + ++F + F
Sbjct: 420 CWRLAFNGAEPVSPDTLERFAARF 443
>UniRef50_A5MZS3 Cluster: Predicted NRPS adenylation domain; n=1;
Clostridium kluyveri DSM 555|Rep: Predicted NRPS
adenylation domain - Clostridium kluyveri DSM 555
Length = 841
Score = 57.2 bits (132), Expect = 4e-07
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 2/144 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A I+ +S + G GV++T ++L + + T+G+ + + + GL L
Sbjct: 164 AFIQFSSGSTGDPKGVVLTHKNLLTNINAIINCAKLTDGDRALSWMPLTHDMGLIGFHLT 223
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGL--LATRDHKEISLS 552
+ + ++ IP L P WMH + +HR S+ + + L +E LS
Sbjct: 224 TTMLKINQYIIPTTLFIRRPNLWMHKVNQHRISLTSSPNFGYKYFLSHFKPESAEEWDLS 283
Query: 553 SLRMLLVADGANPWSLSSCDQFLS 624
+R L+ +GA P S+ C++FL+
Sbjct: 284 CIR--LIFNGAEPISIDLCEEFLN 305
>UniRef50_Q21HW6 Cluster: AMP-dependent synthetase and ligase; n=1;
Saccharophagus degradans 2-40|Rep: AMP-dependent
synthetase and ligase - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 588
Score = 54.8 bits (126), Expect = 2e-06
Identities = 41/175 (23%), Positives = 83/175 (47%), Gaps = 3/175 (1%)
Frame = +1
Query: 115 SLHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSV 294
SL W+ +++L + A+ ++TS + G+ GV+V+ +++ + +
Sbjct: 140 SLQWLISDELEASLANDWKLVAQERDTVAYYQYTSGSTGTPKGVMVSHGNVIYNVSDIDA 199
Query: 295 ACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMH-VIFIPYALMKVSPASWMHMITKHR 471
+ +++E +V L + GL + + V NG H V+F P A + P +W+ I+ +R
Sbjct: 200 SWDHSEDTVLVSWLPIFHDMGLIYGFMQGVYNGFHTVLFSPNAFAQ-RPYTWLKAISDYR 258
Query: 472 ASIAIVKSRDLHWGLLATRDH--KEISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
A+ + + + D K++ LSSLR++ +G+ P S+ F F
Sbjct: 259 ATHSGGPNSAYIMCVEKVLDEQKKDLDLSSLRVMF--NGSEPVRESTLQSFTQAF 311
>UniRef50_A3ZQ92 Cluster: Saframycin Mx1 synthetase B; n=1;
Blastopirellula marina DSM 3645|Rep: Saframycin Mx1
synthetase B - Blastopirellula marina DSM 3645
Length = 1124
Score = 53.6 bits (123), Expect = 5e-06
Identities = 40/175 (22%), Positives = 81/175 (46%), Gaps = 3/175 (1%)
Frame = +1
Query: 118 LHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA 297
+HW++T+ ++ A +++TS + G+ GV+++ ++M+ + ++S A
Sbjct: 146 IHWLATDSEKLVEADQWRMPDIDEKTLAFLQYTSGSTGTPKGVMLSHSNMMHNSALISYA 205
Query: 298 CNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRA 474
+T V L + GL VL + G I + P A ++ P W+ ITK +A
Sbjct: 206 FEHTRSMRAVFWLPMYHDMGLIGGVLQPMQIGQPTILMSPMAFLQ-QPFRWLRAITKSQA 264
Query: 475 SIAIVK--SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFK 633
+++ + +L + + ++ LSS L +GA P + D+F F+
Sbjct: 265 TVSGGPNFAYELCVNKITSEQKDKLDLSSWE--LAFNGAEPIKPETLDRFTEAFE 317
>UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8;
Bacteria|Rep: Non-ribosomal peptide synthase -
Myxococcus xanthus (strain DK 1622)
Length = 3906
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/120 (22%), Positives = 53/120 (44%)
Frame = +1
Query: 124 WVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACN 303
W++T+ L + A +++TS + G+ GV++T +++ + ++ +
Sbjct: 151 WLATDLLEAGCEDGWREPEVTGQTLAFLQYTSGSTGTPKGVMLTHGNLVHNSHLIGLGME 210
Query: 304 YTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 483
EG V L + GL +L + NG H + + P SW+ I +HR + A
Sbjct: 211 LREGSVAVNWLPPYHDMGLIGGILQPLYNGFHGVLLSPITFLQRPLSWLQAIERHRGTCA 270
>UniRef50_Q094Z1 Cluster: Beta-ketoacyl synthase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Beta-ketoacyl synthase -
Stigmatella aurantiaca DW4/3-1
Length = 1072
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/95 (26%), Positives = 49/95 (51%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++T+ G+ GV VT A++L +C L + +T + ++ L + GL VL
Sbjct: 182 AFLQYTAGTLGAPKGVRVTHANLLDNCEALRRSLGHTFTDKILLWLPTHQGLGLLEGVLQ 241
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 483
+ G+H + +P L P W+ ++ H A+++
Sbjct: 242 PLYAGVHCVLMPPQLFFQRPGRWLEALSTHGATVS 276
>UniRef50_Q7NJ79 Cluster: Gll1953 protein; n=1; Gloeobacter
violaceus|Rep: Gll1953 protein - Gloeobacter violaceus
Length = 584
Score = 50.0 bits (114), Expect = 6e-05
Identities = 37/173 (21%), Positives = 72/173 (41%), Gaps = 2/173 (1%)
Frame = +1
Query: 118 LHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA 297
L W+ T+ L A +++TS + + GV++T A++L + +++ A
Sbjct: 150 LQWLCTDPLPETPAESWRPPQVESASIALLQYTSGSTAAPKGVMLTHANVLHNQKLIQSA 209
Query: 298 CNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRAS 477
C++TE V L L AV+ V G + +P P W+ I+++R
Sbjct: 210 CHHTEQSTWVTWLPLHHNLALMSAVVQPVYVGYLSVLMPPPAFLQRPLRWLRAISRYRGR 269
Query: 478 IAIVKSRDLHWGL--LATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
A + + + + E+ LSS + ++ G P ++F + F
Sbjct: 270 GAAGPNFGFNLCIKEIPPEQRGELDLSSWEVAII--GGEPIQCDLLERFSAAF 320
>UniRef50_A7GTF8 Cluster: Beta-ketoacyl synthase; n=3; cellular
organisms|Rep: Beta-ketoacyl synthase - Bacillus cereus
subsp. cytotoxis NVH 391-98
Length = 3099
Score = 50.0 bits (114), Expect = 6e-05
Identities = 40/152 (26%), Positives = 67/152 (44%), Gaps = 4/152 (2%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHA 369
+ PA I+ +S + GVI+T ++L + + + + + + + GL
Sbjct: 185 DTPAFIQFSSGSTSVPKGVILTHRNLLTNIEAMIAGIHLNHEDKSFSWMPYHHDMGLIGF 244
Query: 370 VLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR----DHK 537
L G+H + P W+ ITKHR I + S + + LL +R K
Sbjct: 245 HLVPTAKGIHQFNMSPMKFVKRPNLWLDYITKHR--ITLTGSPNFGYRLLLSRAKEEQFK 302
Query: 538 EISLSSLRMLLVADGANPWSLSSCDQFLSVFK 633
+ L SLR L+ +GA P S+S +F+S K
Sbjct: 303 KWDLRSLR--LIFNGAEPISVSLMREFMSKLK 332
>UniRef50_Q7NJ84 Cluster: Gll1948 protein; n=21; Bacteria|Rep:
Gll1948 protein - Gloeobacter violaceus
Length = 596
Score = 49.2 bits (112), Expect = 1e-04
Identities = 39/173 (22%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
Frame = +1
Query: 118 LHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA 297
L W++T+ L + + A +++TS + G GV++T ++L + RM+ A
Sbjct: 149 LQWLATDNLGTDLADTWQECTFSKDSLAFLQYTSGSTGHPKGVMITHGNLLHNQRMVEGA 208
Query: 298 CNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRAS 477
+++ L + GL VL + G+ + + P W+ IT+HRA+
Sbjct: 209 FGHSDETIFAGWLPLFHDMGLIGNVLQPLHLGIPCVLMSPVDFVQKPRRWLEAITRHRAT 268
Query: 478 IAIVK--SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
+ + DL ++ + + LSS R+ +GA P + F + F
Sbjct: 269 TSGGPNFAYDLCVRKVSAEQREGLDLSSWRVAF--NGAEPVRAHTLQAFAAAF 319
>UniRef50_A5NY43 Cluster: AMP-dependent synthetase and ligase; n=1;
Methylobacterium sp. 4-46|Rep: AMP-dependent synthetase
and ligase - Methylobacterium sp. 4-46
Length = 555
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/100 (30%), Positives = 49/100 (49%)
Frame = +1
Query: 184 ADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLW 363
A++ PA I++TS + S GV+++ ++ A+ RML E + L + GL
Sbjct: 148 AEDHPAVIQYTSGSTTSPKGVVLSHGNLAANLRMLRDGFGAHESSRYLSWLPLFHDMGLI 207
Query: 364 HAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 483
VLA++ NG F P P +W+ I H A+I+
Sbjct: 208 AHVLAALYNGGPCWFAPPLSFFRRPETWLRAIALHGATIS 247
>UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Rep:
Iturin A synthetase A - Bacillus subtilis
Length = 3982
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/146 (23%), Positives = 67/146 (45%)
Frame = +1
Query: 184 ADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLW 363
ADE A I+ +S + G GV++T +++ + + A + + + + GL
Sbjct: 163 ADEL-AFIQFSSGSTGDPKGVMLTHHNLIHNTCAIGTALAIHSKDSFLSWMPLTHDMGLI 221
Query: 364 HAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEI 543
L + G++ +P L P WM +H+ASI + ++ L ++ +
Sbjct: 222 ACHLVPFITGINQNLMPTELFIRRPILWMKKAHEHKASILSSPNFGYNYFLKFLKNEPDW 281
Query: 544 SLSSLRMLLVADGANPWSLSSCDQFL 621
LS ++ ++A+GA P CD+FL
Sbjct: 282 DLSHIK--VIANGAEPILPELCDEFL 305
>UniRef50_Q0LNS7 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 4101
Score = 48.8 bits (111), Expect = 1e-04
Identities = 37/144 (25%), Positives = 68/144 (47%), Gaps = 2/144 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A+++ +S + G GV ++ A +LA+ + AC + +V + + + GL A L
Sbjct: 182 AYLQFSSGSTGQPRGVELSHAGLLANLYQMGSACAINSQDSVVSWMPYYHDMGLIAAHLL 241
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASI--AIVKSRDLHWGLLATRDHKEISLS 552
+ G+ + I PA W+ + +H+AS+ A + DL + + L
Sbjct: 242 PLAAGIKQVKIDEFYFARRPAIWLEITHQHQASLLTAAPFALDLVNRRVKPAQLVGLDLR 301
Query: 553 SLRMLLVADGANPWSLSSCDQFLS 624
+R+L+V GA P +SC FL+
Sbjct: 302 CVRLLIV--GAEPIVAASCRAFLA 323
>UniRef50_Q8DTJ2 Cluster: Putative peptide synthetase; n=1;
Streptococcus mutans|Rep: Putative peptide synthetase -
Streptococcus mutans
Length = 633
Score = 48.4 bits (110), Expect = 2e-04
Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 5/151 (3%)
Frame = +1
Query: 205 IEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASV 384
++ +S + G GVI T ++ + + + + E ++ L GL LA +
Sbjct: 150 VQFSSGSTGEPKGVIYTDNTLSTNMFSILKSTEWKTEERILTWLTLTHNMGLASGHLAPL 209
Query: 385 LNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK--SRDLHWGLLATRDHKEISLSSL 558
+ GM+ +P V P +W++ I K++ +I + L L T ++ LSS+
Sbjct: 210 IKGMNQYLMPTREFIVHPINWLYQIDKYKINIVSCPNFASKLLIKTLNTTKINDVDLSSI 269
Query: 559 RMLLVADGANPWSLSSCDQF---LSVFKARE 642
M++ +G+ P C++ LS +K RE
Sbjct: 270 NMII--NGSEPIDYGLCEELTKHLSKYKLRE 298
>UniRef50_Q5P000 Cluster: CoA ligase, AMP generating; n=2;
Betaproteobacteria|Rep: CoA ligase, AMP generating -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 831
Score = 48.4 bits (110), Expect = 2e-04
Identities = 36/146 (24%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + G GV ++ A++LA+ R N + + V L + GL A L
Sbjct: 206 ALVQYTSGSTGDPKGVTLSHANLLANIRAYGRVLNVSSTDVCVSWLPLYHDMGLIGAWLG 265
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK--SRDLHWGLLATRDHKEISLS 552
S+ + ++ + P W+ I +HR +I + +L L RD + L+
Sbjct: 266 SLYHACPLVLMSPLDFLARPECWLWAIHRHRGTITAAPNFAFELCVKRLGDRDLAGLDLA 325
Query: 553 SLRMLLVADGANPWSLSSCDQFLSVF 630
S ++ + +GA P S + ++F F
Sbjct: 326 SWQIAM--NGAEPVSAGTLERFADAF 349
>UniRef50_Q8YPY3 Cluster: Alr4057 protein; n=5; Cyanobacteria|Rep:
Alr4057 protein - Anabaena sp. (strain PCC 7120)
Length = 602
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/130 (19%), Positives = 58/130 (44%), Gaps = 2/130 (1%)
Frame = +1
Query: 94 VSFRGWPSLHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLA 273
+ F + + W ++E + A++++TS + + GV+++ +++
Sbjct: 132 LDFPEFEEMTWFASEDIDLELADQWQDPEITPNTLAYLQYTSGSTSTPKGVMISHHNIMH 191
Query: 274 HCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI--PYALMKVSPASW 447
HC L AC Y + + + + GL + + NG H ++ P + +K P W
Sbjct: 192 HCAYLQKACGYDTESVSITWMPYFHDYGLVEGLTVPIYNG-HPCYVMSPMSFIK-QPVRW 249
Query: 448 MHMITKHRAS 477
+ I+++R +
Sbjct: 250 LQAISRYRGT 259
>UniRef50_Q2SG85 Cluster: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Hahella
chejuensis KCTC 2396|Rep: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Hahella chejuensis
(strain KCTC 2396)
Length = 552
Score = 47.6 bits (108), Expect = 3e-04
Identities = 26/97 (26%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
P I++TS + + GV V+ ++LA+ R+ + + ++M+ L + GL+ +++
Sbjct: 176 PVIIQYTSGSTKAPRGVKVSERNILANQRISAEKWRFAPEKNMLSWLPHYHDMGLFGSII 235
Query: 376 ASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIA 483
++ GM I + P +K P W+ ++KHRA+I+
Sbjct: 236 YPLMTGMQCILMSPVDFIK-QPLRWLSAVSKHRAAIS 271
>UniRef50_Q0M3P0 Cluster: AMP-dependent synthetase and ligase; n=1;
Caulobacter sp. K31|Rep: AMP-dependent synthetase and
ligase - Caulobacter sp. K31
Length = 577
Score = 47.2 bits (107), Expect = 4e-04
Identities = 42/148 (28%), Positives = 65/148 (43%), Gaps = 4/148 (2%)
Frame = +1
Query: 205 IEHTSAADGSAMGVIVTRASMLAH--CRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
++ TS + + GVIVT +++A+ C M + V L + GL VL
Sbjct: 173 LQFTSGSTSTPRGVIVTHRALVANIACFMDQSLQADPARDKGVTWLPLYHDMGLIGFVLG 232
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGL--LATRDHKEISLS 552
V G+ V+F+P SPA+W+ + +HR +I + L L D LS
Sbjct: 233 PVHTGVSVVFMPTVRFAKSPAAWLDALHQHRGTITFAPNFAFALLLRRLRAEDLGRWDLS 292
Query: 553 SLRMLLVADGANPWSLSSCDQFLSVFKA 636
++ L GA P ++FL VF A
Sbjct: 293 CVKAL--GCGAEPIHPDLIERFLDVFAA 318
>UniRef50_A5IE32 Cluster: Saframycin Mx1 synthetase B; n=4;
Legionella pneumophila|Rep: Saframycin Mx1 synthetase B
- Legionella pneumophila (strain Corby)
Length = 581
Score = 47.2 bits (107), Expect = 4e-04
Identities = 32/146 (21%), Positives = 69/146 (47%), Gaps = 1/146 (0%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + GV+V+ ++L + + + + + + L + GL +L
Sbjct: 168 AFLQYTSGSTMHPKGVMVSHHNLLDNLGKIFTSFHMNDETIIFSWLPPHHDMGLIGCILT 227
Query: 379 SVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSS 555
+ G+ I + P++ ++ +P SW+ ITK+RA+I+ + + + R+ K+ L
Sbjct: 228 PIYGGIQAIMMSPFSFLQ-NPLSWLKHITKYRATISGSPNFAYDYCVKRIREEKKEGLDL 286
Query: 556 LRMLLVADGANPWSLSSCDQFLSVFK 633
+ +GA P + + F FK
Sbjct: 287 SSWVTAFNGAEPVRAETMEHFYQAFK 312
>UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2;
Streptomyces|Rep: Nonribosomal peptide synthetase -
Streptomyces atroolivaceus
Length = 1745
Score = 46.4 bits (105), Expect = 7e-04
Identities = 43/176 (24%), Positives = 75/176 (42%), Gaps = 5/176 (2%)
Frame = +1
Query: 118 LHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA 297
+ W+ TE + A A +++TS + G+ GV+V +++ + +S A
Sbjct: 141 IQWLVTEDIADAAADDWPGTGPAPADLAFLQYTSGSTGTPKGVMVRHDNLVHNSASISTA 200
Query: 298 CNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRA 474
V L + GL +L + G I P A ++ SP W+ I++HRA
Sbjct: 201 LGVGPDSRGVSWLPPYHDMGLIGGILQPLYAGFPCTLISPMAFVR-SPYRWLDAISRHRA 259
Query: 475 SIAIVKSRDLHWGLLATR----DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
+++ + D +G R E+ LSS + +V GA P ++ D F F
Sbjct: 260 TVS--AAPDFAYGECVRRIPEDKRAELDLSSWQHAMV--GAEPVRPATLDAFARAF 311
>UniRef50_Q0B1F1 Cluster: Beta-ketoacyl synthase; n=1; Burkholderia
ambifaria AMMD|Rep: Beta-ketoacyl synthase -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 1474
Score = 46.4 bits (105), Expect = 7e-04
Identities = 37/150 (24%), Positives = 69/150 (46%), Gaps = 4/150 (2%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + G+ GV+++ A++L++ +++ A + V L + G + VL
Sbjct: 167 ALLQYTSGSTGTPKGVMISHANILSNMAVIAEASDADASTVFVSWLPVFHDMGFFGKVLL 226
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKE----IS 546
+ G+ + + A P W+ ITK+R + + D + L A + E +
Sbjct: 227 PIYLGVPAVLMAPAAFVQKPIRWLQAITKYRGTHC--AAPDFAYDLCARKISDEARALLD 284
Query: 547 LSSLRMLLVADGANPWSLSSCDQFLSVFKA 636
LSS R+ +GA P S +F F A
Sbjct: 285 LSSWRVAF--NGAEPVRAESVARFSRAFAA 312
>UniRef50_A0PWU0 Cluster: Polyketide synthase Pks16_1; n=1;
Mycobacterium ulcerans Agy99|Rep: Polyketide synthase
Pks16_1 - Mycobacterium ulcerans (strain Agy99)
Length = 550
Score = 46.4 bits (105), Expect = 7e-04
Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 6/134 (4%)
Frame = +1
Query: 187 DECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNY-TEGEHMVCVLDFKRETGLW 363
++ PA ++ TS + G V +T ++ A+ R L A + + +V L + G+
Sbjct: 159 EDSPAFLQLTSGSTGHPKAVSITYRNIEANGRALMAAASADVASDVVVSWLPLFHDMGMM 218
Query: 364 HAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR----- 528
++ + GM + I A P W +ITKHR S I + + + LLA R
Sbjct: 219 GLLIIPMYEGMDAVHITPADFLNDPLLWAELITKHRGS--ITAAPNFAYSLLARRLRRAQ 276
Query: 529 DHKEISLSSLRMLL 570
DH LSSLR L
Sbjct: 277 DH-AFDLSSLRFAL 289
>UniRef50_UPI0001597892 Cluster: NrsF; n=1; Bacillus
amyloliquefaciens FZB42|Rep: NrsF - Bacillus
amyloliquefaciens FZB42
Length = 549
Score = 45.2 bits (102), Expect = 0.002
Identities = 33/145 (22%), Positives = 63/145 (43%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A I+ +S G GVI+T +++ + L+ A ++ + + + + GL LA
Sbjct: 160 AFIQFSSGTTGDPKGVILTHKNLITNISALNEAWETSKSDSSLSWMPLTHDMGLIAIHLA 219
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSL 558
S + IP ++ P W+ +HR + + + L + ++ +
Sbjct: 220 STYKKIQQYIIPTSVFIRRPTLWLLKTHQHRVTQLYSPNFGYKFLLDNYKKNQIYNWDLT 279
Query: 559 RMLLVADGANPWSLSSCDQFLSVFK 633
+ L+A+GA P S S C +FL K
Sbjct: 280 CVRLLANGAEPISTSLCQRFLEEMK 304
>UniRef50_Q4BZ64 Cluster: AMP-dependent synthetase and ligase; n=1;
Crocosphaera watsonii WH 8501|Rep: AMP-dependent
synthetase and ligase - Crocosphaera watsonii
Length = 579
Score = 45.2 bits (102), Expect = 0.002
Identities = 33/147 (22%), Positives = 69/147 (46%), Gaps = 1/147 (0%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + G+ GVIV+ ++L + + A TEG V L + GL ++
Sbjct: 107 AFLQYTSGSTGNPKGVIVSHENILHNSAYIQTAFQLTEGSVSVTWLPSFHDMGLIDGIIQ 166
Query: 379 SVLNG-MHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSS 555
+ G + VI P A ++ P W+ I+ +RA+ + + + + + +L
Sbjct: 167 PLYTGFLGVIMSPQAFLQ-KPIRWLEAISYYRATHSGGPNLGYDLCVEKVTNEQTRNLDL 225
Query: 556 LRMLLVADGANPWSLSSCDQFLSVFKA 636
L +G+ P + ++F++ F++
Sbjct: 226 SCWLSAYNGSEPIQYKTLERFINKFQS 252
>UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2;
Comamonadaceae|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 1789
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/95 (22%), Positives = 49/95 (51%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + + GV+V+ +++A+ + + G+ + + GL +L
Sbjct: 176 AFLQYTSGSTSAPKGVMVSHGNLIANEAAIQQRMDIGAGDRFMSWAPLYHDMGLIGGLLQ 235
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 483
+ +G+ ++ L SP W+ +I++HRA+I+
Sbjct: 236 PLYSGLPLVLTSPRLFLESPVRWLELISRHRATIS 270
>UniRef50_Q127J0 Cluster: AMP-dependent synthetase and ligase; n=5;
Proteobacteria|Rep: AMP-dependent synthetase and ligase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 942
Score = 44.8 bits (101), Expect = 0.002
Identities = 44/178 (24%), Positives = 77/178 (43%), Gaps = 5/178 (2%)
Frame = +1
Query: 112 PSLHWVST-EKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRML 288
PSL V T E+L A++ A +++TS + S GV++T A++LA+ R +
Sbjct: 249 PSLRMVCTVEELSASTASPERVTAHANDI-ALLQYTSGSTSSPKGVVLTHANLLANLRAM 307
Query: 289 SVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKH 468
A + + V L + GL A L S+ ++ + P W+ + +H
Sbjct: 308 GQALQVSSEDVFVSWLPLYHDMGLIGAWLGSLYYAYPLVVMSPLTFLARPERWLWAVHRH 367
Query: 469 RASIAIVKSRDLHWGL-LATRDHKEISLSSLRM---LLVADGANPWSLSSCDQFLSVF 630
R ++ S ++G L R E +L L + +GA P S ++ +F F
Sbjct: 368 RGTL----SGGPNFGYELCLRKLDEAALEGLDLSSWRFAFNGAEPVSATTMQEFQQRF 421
>UniRef50_A4BLA6 Cluster: Hypothetical acyltransferase family
protein; n=1; Nitrococcus mobilis Nb-231|Rep:
Hypothetical acyltransferase family protein -
Nitrococcus mobilis Nb-231
Length = 937
Score = 44.8 bits (101), Expect = 0.002
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + G G+ + +LA+ R + T + V L + GL A
Sbjct: 278 AMLQYTSGSTGDPKGISLAHKHLLANIRAIGGRIEATSEDFFVSWLPLYHDMGLIGAWFG 337
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH--KEISLS 552
S+ G + + P W+ I +HRA+++ + + A R + + LS
Sbjct: 338 SLYFGCPLAIMSPLAFLAHPLQWLWTIHRHRATLSASPNFGYELCVRAARSGALEGMDLS 397
Query: 553 SLRMLLVADGANPWSLSSCDQFLSVFKA 636
S R + +GA S ++ D+F + F+A
Sbjct: 398 SWR--IAFNGAESVSPATLDRFYATFRA 423
>UniRef50_Q82U49 Cluster: AMP-dependent synthetase and ligase; n=3;
Nitrosomonadaceae|Rep: AMP-dependent synthetase and
ligase - Nitrosomonas europaea
Length = 610
Score = 44.4 bits (100), Expect = 0.003
Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTE---GEHMVCVLDFKRETGLWHA 369
A+++ TS + GV++T +++ + R + CN + G+ L F + GL
Sbjct: 204 AYLQFTSGSTRLPRGVVITERALMTNLR--GIVCNGLDVRLGDRCASWLPFYHDMGLVGL 261
Query: 370 VLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR--DHKEI 543
VLA + + V ++ V P W+ +I+++R +IA + L L R D ++
Sbjct: 262 VLAPLAAQLSVDYLATRDFAVRPLQWLKLISRNRCTIAFSQPFGLKLCTLRARESDLADL 321
Query: 544 SLSSLRMLLVADGANPWSLSSCDQFLSVFKA 636
LS R V GA + + F + F A
Sbjct: 322 DLSCWRAAGV--GAEMIRMDTLKSFAAKFAA 350
>UniRef50_Q096N9 Cluster: Beta-ketoacyl synthase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Beta-ketoacyl synthase -
Stigmatella aurantiaca DW4/3-1
Length = 745
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/171 (16%), Positives = 69/171 (40%)
Frame = +1
Query: 118 LHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA 297
+ W++T+ + + + +++TS + + GV+VT A+++A+ L+
Sbjct: 166 VEWIATDAVDVNQASEWQRPNIGPQTLSFLQYTSGSTATPKGVMVTHANLVANTMALTSV 225
Query: 298 CNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRAS 477
+VC L + GL V+ + G H + + +P W+ ++ ++A+
Sbjct: 226 VKTHRDSTLVCWLPLFHDMGLIGNVIHAAYVGFHCVLMAPTTFLQNPFLWVKAMSDYKAT 285
Query: 478 IAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
+ + +L + +GA P + ++FL +F
Sbjct: 286 FTGGPNFGYELCNRKVTAEQRATLDLSHLETAYNGAEPVRYETLERFLELF 336
>UniRef50_Q9LW70 Cluster: Long-chain-fatty-acid-CoA ligase-like
protein; n=7; Magnoliophyta|Rep:
Long-chain-fatty-acid-CoA ligase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 608
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/73 (34%), Positives = 37/73 (50%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
PA I +TS G GV+ T S+ + RML+ A YT +H + L GL++A+
Sbjct: 236 PALIVYTSGTTGKPKGVVHTHNSINSQVRMLTEAWEYTSADHFLHCLPLHHVHGLFNALF 295
Query: 376 ASVLNGMHVIFIP 414
A + V F+P
Sbjct: 296 APLYARSLVEFLP 308
>UniRef50_Q83AH1 Cluster: Acyltransferase family protein; n=4;
Coxiella burnetii|Rep: Acyltransferase family protein -
Coxiella burnetii
Length = 853
Score = 43.2 bits (97), Expect = 0.007
Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 3/156 (1%)
Frame = +1
Query: 112 PSLHWVSTEKLXXXXXXXXXXXXXADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLS 291
PSL V+T K P I++TS + G+ GV++ A++LA+
Sbjct: 159 PSLLEVTTVKALTDISADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYG 218
Query: 292 VACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKH 468
N + V L + GL A + S +G+ + + P+ + P W+ I H
Sbjct: 219 KTLNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLS-RPEKWLWAIHYH 277
Query: 469 RASIAIVK--SRDLHWGLLATRDHKEISLSSLRMLL 570
R +I+ + DL + D + + LSS R+ L
Sbjct: 278 RGTISPGPNFAYDLCVKKIEDSDLEGLDLSSWRVAL 313
>UniRef50_Q3DZ13 Cluster: AMP-dependent synthetase and ligase; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: AMP-dependent
synthetase and ligase - Chloroflexus aurantiacus J-10-fl
Length = 498
Score = 42.7 bits (96), Expect = 0.009
Identities = 25/70 (35%), Positives = 37/70 (52%)
Frame = +1
Query: 184 ADECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLW 363
ADE A I +TS G A G + T AS+ A+C +S A +TE + ++ +L GL
Sbjct: 149 ADEM-ALIAYTSGTTGRAKGAVHTHASLAANCAAISTAWRWTEHDRLLLMLPLFHVHGLG 207
Query: 364 HAVLASVLNG 393
V ++ NG
Sbjct: 208 VGVHGTIRNG 217
>UniRef50_Q08ST3 Cluster: Saframycin Mx1 synthetase B; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Saframycin Mx1
synthetase B - Stigmatella aurantiaca DW4/3-1
Length = 583
Score = 42.7 bits (96), Expect = 0.009
Identities = 29/149 (19%), Positives = 70/149 (46%), Gaps = 5/149 (3%)
Frame = +1
Query: 187 DECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWH 366
++ A ++ +S + GV +T ++ A+ RM+ + V L + GL
Sbjct: 148 EDALAFVQFSSGSTAFPKGVPITWRNLHANLRMIQNQGALCAQDRCVSWLPLYHDMGLVG 207
Query: 367 AVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGL-----LATRD 531
+LA + + + P W+ +++HR ++A++ + + + L L +
Sbjct: 208 GMLACMYGHCDSLLTQPMSFLMDPMGWLEFLSEHRGTLAVIPNFAIDYTLKILNGLGAEE 267
Query: 532 HKEISLSSLRMLLVADGANPWSLSSCDQF 618
+E+ LS+LR + + G+ P ++++ ++F
Sbjct: 268 LRELDLSALRTVYL--GSEPINIANLERF 294
>UniRef50_Q113H9 Cluster: AMP-dependent synthetase and ligase; n=2;
Cyanobacteria|Rep: AMP-dependent synthetase and ligase -
Trichodesmium erythraeum (strain IMS101)
Length = 991
Score = 41.9 bits (94), Expect = 0.016
Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 1/146 (0%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + G GV++T ++L + M + T V L F TGL VL
Sbjct: 164 AFLQYTSGSTGKPKGVMITHKNILHNLAMGYEQSDITPESITVTWLPFSHNTGLLVGVLQ 223
Query: 379 SVLNGMHV-IFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSS 555
+ V I P ++ P W+ ++ ++A+ ++ + T + L
Sbjct: 224 PLYGNFPVKIMSPLDFLQ-KPFRWLMAMSHYKATQSLAPNFAYDLVCFQTTPEERAMLDL 282
Query: 556 LRMLLVADGANPWSLSSCDQFLSVFK 633
L GA P + ++F+ FK
Sbjct: 283 SNWELALSGAEPIRAETFERFIKTFK 308
>UniRef50_A7HI15 Cluster: AMP-dependent synthetase and ligase; n=4;
Cystobacterineae|Rep: AMP-dependent synthetase and
ligase - Anaeromyxobacter sp. Fw109-5
Length = 586
Score = 41.9 bits (94), Expect = 0.016
Identities = 32/142 (22%), Positives = 59/142 (41%)
Frame = +1
Query: 205 IEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASV 384
++ +S + V ++ A++ A L A + +V L + GL +LA++
Sbjct: 172 VQFSSGSTVDPKAVALSHAALQAQADALMAAVRPDARDALVSWLPLYHDMGLIGCLLAAM 231
Query: 385 LNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRM 564
++ IP PA W+ I +HR +I++ S + D + S
Sbjct: 232 SYPGPLVLIPPEHFLARPALWLRAIARHRGTISVAPSFAYAFCAERVADAELAGSSLASW 291
Query: 565 LLVADGANPWSLSSCDQFLSVF 630
L +GA P S + +FL+ F
Sbjct: 292 RLALNGAEPVSADALRRFLARF 313
>UniRef50_Q7UYT8 Cluster: Saframycin Mx1 synthetase B; n=2;
Bacteria|Rep: Saframycin Mx1 synthetase B -
Rhodopirellula baltica
Length = 1204
Score = 40.7 bits (91), Expect = 0.036
Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 1/144 (0%)
Frame = +1
Query: 205 IEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASV 384
+++TS + GS GV++T+A+++A+ ++ L + GL VL +
Sbjct: 204 LQYTSGSTGSPKGVMLTQANLIANSELILHGFEPESTIIGASWLPTYHDMGLVGGVLMPM 263
Query: 385 LNGMH-VIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLR 561
G H ++ P A ++ P+ W+ I +H+ +I+ + + RD + +
Sbjct: 264 FVGRHNILMSPMAFLQ-RPSRWLQTIARHQVTISGGPNFAYQLCVDKIRDEELEGVDLSS 322
Query: 562 MLLVADGANPWSLSSCDQFLSVFK 633
+ +GA P S+ D F F+
Sbjct: 323 WEIAFNGAEPVRSSTLDAFSKRFE 346
>UniRef50_A3YGJ3 Cluster: Beta-ketoacyl synthase; n=1; Marinomonas
sp. MED121|Rep: Beta-ketoacyl synthase - Marinomonas sp.
MED121
Length = 714
Score = 40.7 bits (91), Expect = 0.036
Identities = 28/147 (19%), Positives = 67/147 (45%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHA 369
E A+++++S + GS GV++ +++ + ++ + TE ++V L + G
Sbjct: 168 ETVAYLQYSSGSTGSPKGVMLGHGNLIQNTALIVQELSLTECGNIVSWLPMYHDMGFVGF 227
Query: 370 VLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISL 549
VLA + G V + ++ +P W+ I+ H+A ++ + + + ++ +L
Sbjct: 228 VLAPMCAGASVWLLLPPVVLQAPFLWLKAISDHKAVLSGGPNFIYEHCVARVSEEQKQTL 287
Query: 550 SSLRMLLVADGANPWSLSSCDQFLSVF 630
+GA P ++ ++F F
Sbjct: 288 DLSHWRFAVNGAEPIHTATLEKFNQTF 314
>UniRef50_UPI000011F913 Cluster: UPI000011F913 related cluster; n=1;
unknown|Rep: UPI000011F913 UniRef100 entry - unknown
Length = 1261
Score = 40.3 bits (90), Expect = 0.048
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 3/150 (2%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHA 369
E +++TS + GV+V +++ + R++ + G L + GL
Sbjct: 192 EALCFLQYTSGSTSEPKGVMVPHGALVHNLRLMRDCHGWHGGMTWCSWLPAYHDMGLIAM 251
Query: 370 VLASV-LNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK--SRDLHWGLLATRDHKE 540
+LA + L G V+ +K P SW+ +I +HRA I+ + DL L
Sbjct: 252 MLAPLYLGGTAVLMSSTDFLK-RPVSWLRLIERHRAEISCAPNFAYDLCARRLTEEQTAG 310
Query: 541 ISLSSLRMLLVADGANPWSLSSCDQFLSVF 630
+ LSS R +GA P ++ +F F
Sbjct: 311 LDLSSWR--YACNGAEPVDAATLTRFAERF 338
>UniRef50_Q0C1U0 Cluster: Putative AMP binding protein; n=1;
Hyphomonas neptunium ATCC 15444|Rep: Putative AMP
binding protein - Hyphomonas neptunium (strain ATCC
15444)
Length = 591
Score = 40.3 bits (90), Expect = 0.048
Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCR-MLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
++I+ +S + G++ T+AS+ A+C+ ++ G+ V L + GL +
Sbjct: 185 SYIQFSSGSTSEPKGIVATQASLSANCKAIIQEGLQVRAGDRAVSWLPLYHDMGLVGFFI 244
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKE-ISLS 552
A + + + + F+ P +W+ +I+ ++ +++ S + L R E + LS
Sbjct: 245 APMYSQLSIDFLSPTDFARRPGTWLKLISANKGTLSY--SPSFGYELCVRRFRGEPLDLS 302
Query: 553 SLRMLLVADGANPWSLSSCDQFLSVFKA 636
S R + G + + DQF F A
Sbjct: 303 SWRAAGI--GGDMVRADALDQFSETFAA 328
>UniRef50_Q2JBN8 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. CcI3|Rep: AMP-dependent synthetase and
ligase - Frankia sp. (strain CcI3)
Length = 648
Score = 39.5 bits (88), Expect = 0.084
Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 1/145 (0%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A ++ TS + + GV+++ ++L R + EG+H L + GL+ A L+
Sbjct: 235 AIVQFTSGSTAAPKGVVLSHRAVLCGIRAIIDGIRLGEGDHGGIWLPLFHDMGLF-ATLS 293
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEI-SLSS 555
+++ G+ + A PA W+ A+I+ + + L+ D E+ L
Sbjct: 294 AIMTGIPMTVWSPADFVRDPAGWLRSFLASGATISPAPN-FAYDDLVRAIDPDEVPGLDM 352
Query: 556 LRMLLVADGANPWSLSSCDQFLSVF 630
R + +GA P S ++FL F
Sbjct: 353 RRWRVALNGAEPVSAVGVERFLDHF 377
>UniRef50_Q06YY4 Cluster: Acyl-CoA ligase/dehydrogenase fusion
protein; n=1; Streptomyces fungicidicus|Rep: Acyl-CoA
ligase/dehydrogenase fusion protein - Streptomyces
fungicidicus
Length = 1177
Score = 39.5 bits (88), Expect = 0.084
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 2/134 (1%)
Frame = +1
Query: 235 AMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIP 414
A GVI+T ++LA+ + + L + GL+ + A++L G H+ +
Sbjct: 182 AEGVILTHGAVLANVSAVCTYVGLVPEDRFGSWLPLHHDMGLFTQLTAALLCGAHLTLMT 241
Query: 415 YALMKVSPASWMHMITKHRASIAIVK--SRDLHWGLLATRDHKEISLSSLRMLLVADGAN 588
A PA W M+ + R + + + +L ++ + + LS+LR L +GA
Sbjct: 242 PAQFIRRPAEWFRMLDRFRITYTVAPNFAYELCTRVITDEMTRGLDLSALRYL--GNGAE 299
Query: 589 PWSLSSCDQFLSVF 630
P + F+ F
Sbjct: 300 PIHAPTVRAFMERF 313
>UniRef50_A5UV23 Cluster: AMP-dependent synthetase and ligase; n=2;
Roseiflexus|Rep: AMP-dependent synthetase and ligase -
Roseiflexus sp. RS-1
Length = 520
Score = 39.5 bits (88), Expect = 0.084
Identities = 36/147 (24%), Positives = 69/147 (46%), Gaps = 1/147 (0%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A I +TS G GV+++ + L + AC + + ++C+L +A +A
Sbjct: 166 ASIIYTSGTTGRPKGVLLSHGNYLFDVWSYATACQISAADRLLCMLPLFHV----NAQVA 221
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRA-SIAIVKSRDLHWGLLATRDHKEISLSS 555
SVL+ +H L SP ++ + ++RA S + V + ++ L D + LS+
Sbjct: 222 SVLSALHQGGALILLEGFSPREFLPALARYRATSFSAVPT--IYAILNNLPDASQYDLSN 279
Query: 556 LRMLLVADGANPWSLSSCDQFLSVFKA 636
LR+ + GA P + ++F ++A
Sbjct: 280 LRVCIC--GAAPMPVEVFERFEQTYRA 304
>UniRef50_Q0LUE8 Cluster: AMP-dependent synthetase and ligase; n=1;
Caulobacter sp. K31|Rep: AMP-dependent synthetase and
ligase - Caulobacter sp. K31
Length = 548
Score = 39.1 bits (87), Expect = 0.11
Identities = 37/130 (28%), Positives = 54/130 (41%)
Frame = +1
Query: 211 HTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLN 390
+TS G GV+ + S + H MLS A N T + M+ V+ G W A +
Sbjct: 197 YTSGTTGDPKGVLYSHRSNVLHAMMLSPALNLTSHDVMMPVVPMFHANG-WGLPYACPMV 255
Query: 391 GMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLL 570
G ++ AL PAS +H + + + L LL S+LR +L
Sbjct: 256 GAAMVMPGAAL---DPAS-LHALMEAQGVTITAGVPTLWQSLLQHMKDTGARFSTLRTIL 311
Query: 571 VADGANPWSL 600
VA A P +L
Sbjct: 312 VAGSAAPRAL 321
>UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Similar
to antibiotic synthetase - Photorhabdus luminescens
subsp. laumondii
Length = 1065
Score = 38.7 bits (86), Expect = 0.15
Identities = 19/95 (20%), Positives = 48/95 (50%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
PA+I +TS + G GV+VT +++ + N++E + + + +W
Sbjct: 610 PAYIIYTSGSTGVPKGVVVTHHNVMRLLQSTQRWFNFSETDCWTMFHSYAFDFAVWEC-W 668
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
++LNG ++ +P+ + + SP ++ ++ + ++
Sbjct: 669 GALLNGGRLVIVPWEVSR-SPTDFLQLLVSEKVTV 702
>UniRef50_Q3JM63 Cluster: Peptide synthetase NRPS5-4-3; n=16;
Burkholderia|Rep: Peptide synthetase NRPS5-4-3 -
Burkholderia pseudomallei (strain 1710b)
Length = 1005
Score = 38.7 bits (86), Expect = 0.15
Identities = 21/92 (22%), Positives = 42/92 (45%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + GV+V +++A+ RM++ A + V + + GL +L
Sbjct: 576 AFLQYTSGSTSRPKGVVVRHRNLVANERMIAQAMSLDHASTSVVWMPHYHDMGLIGGMLQ 635
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRA 474
+ +G H + + P W+ I + RA
Sbjct: 636 PLYSGAHCVAMAPTTFLKRPLRWLRAIAQWRA 667
>UniRef50_Q6H901 Cluster: Putative odorant-binding protein OBPjj10
precursor; n=1; Anopheles gambiae|Rep: Putative
odorant-binding protein OBPjj10 precursor - Anopheles
gambiae (African malaria mosquito)
Length = 207
Score = 38.3 bits (85), Expect = 0.19
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Frame = +2
Query: 101 FAVGRPYIGCRPRNCRVRRATGSRLLVRLMNVQRT-SNTPPPLTDPQWELSLPGLQCWRT 277
FAV + C +VR ATGSR+ + + + S PPP P W LS G R
Sbjct: 10 FAVVLTLLACTVTGAKVRFATGSRVQSKNFKLYSSLSFFPPPCRVPGWRLSTSGASI-RM 68
Query: 278 VGCSRWPATTPRVSTWCA 331
+R A PR + CA
Sbjct: 69 HASARKRAYCPRTRSACA 86
>UniRef50_A6E4W0 Cluster: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Roseovarius sp.
TM1035|Rep: Acyl-CoA synthetases (AMP-forming)/AMP-acid
ligases II - Roseovarius sp. TM1035
Length = 563
Score = 37.5 bits (83), Expect = 0.34
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Frame = +1
Query: 205 IEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASV 384
I+HTS + V +T + A+C ML V L + GL +L ++
Sbjct: 179 IQHTSGSTRFPKAVPITSQQIRANCAMLQRLWGVNAETVTVNWLPHYHDMGLMGGILYTL 238
Query: 385 LN-GMHVIFIPYALMKVSPASWMHMITKHRASIA 483
L+ G + P+ +++ SP SW+ I+ +RA+ +
Sbjct: 239 LSGGQSLQMSPFEMIR-SPLSWLKAISTYRATFS 271
>UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2596
Score = 37.1 bits (82), Expect = 0.45
Identities = 23/99 (23%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVL--DFKRETGLW 363
E PA++ +TS + G+ GV+V+ A++ ML+ Y +H V L + + +W
Sbjct: 597 ENPAYVIYTSGSTGNPKGVVVSHANVAR--LMLATNAWYQFNQHDVWTLFHSYAFDFSVW 654
Query: 364 HAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
+ ++L G H++ +PY + + +P ++ ++ + ++
Sbjct: 655 E-LWGALLYGGHLVVVPYWVSR-NPEAFHQLLRQQHVTV 691
>UniRef50_A3ILP8 Cluster: Beta-ketoacyl synthase; n=1; Cyanothece
sp. CCY 0110|Rep: Beta-ketoacyl synthase - Cyanothece
sp. CCY 0110
Length = 689
Score = 37.1 bits (82), Expect = 0.45
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +1
Query: 109 WPS-LHWVSTEKLXXXXXXXXXXXXXADECP-AHIEHTSAADGSAMGVIVTRASMLAHCR 282
WP L ++ T++L D A ++ TS + GV+++ ++ L++
Sbjct: 136 WPEELPYIVTDRLFNLSPLATPELPDLDGSTLAFLQFTSGSTSLPKGVMISHSNCLSNLE 195
Query: 283 MLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMIT 462
M + T V L + GL +L S G H + + P W+ IT
Sbjct: 196 MALSVTSATPESTFVSWLPHYHDLGLVAHLLHSFYGGSHCVILAPTTFVSRPLEWLRAIT 255
Query: 463 KHRASI--AIVKSRDLHWGLLATRDHKEISLSSLRMLLVA 576
+ A + L + + K + LS LRM + A
Sbjct: 256 NYGGQYTGAPNFAYQLCVDKIRPEEQKNLDLSCLRMAINA 295
>UniRef50_Q0SK67 Cluster: Probable non-ribosomal peptide synthetase;
n=1; Rhodococcus sp. RHA1|Rep: Probable non-ribosomal
peptide synthetase - Rhodococcus sp. (strain RHA1)
Length = 855
Score = 36.7 bits (81), Expect = 0.59
Identities = 27/128 (21%), Positives = 58/128 (45%)
Frame = +1
Query: 187 DECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWH 366
D PA++ +TS + G GV++ ++ A + T G+ + +W
Sbjct: 395 DGAPAYVVYTSGSTGRPKGVVIPHRAVPALMSATATEFAPTPGDTWSMFHSPAFDFSVWE 454
Query: 367 AVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEIS 546
+ S+ G ++ +PY + + SP + ++ R ++++ + LLA D
Sbjct: 455 -IWGSLSTGGRLVIVPYWISR-SPVEFHTLLADER--VSVLSQTPSAFVLLAAADRDLEP 510
Query: 547 LSSLRMLL 570
LS+LR+++
Sbjct: 511 LSALRLVV 518
>UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5;
root|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 3235
Score = 36.7 bits (81), Expect = 0.59
Identities = 32/143 (22%), Positives = 61/143 (42%), Gaps = 2/143 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A I+ +S + G GVI+T ++L + N + + + + GL +
Sbjct: 166 AFIQFSSGSTGDPKGVIITHKNVLYDIGSVIRWVNINSEDSGLNWMPLTHDMGLIGTHIK 225
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGL--LATRDHKEISLS 552
V+ ++ I L P+ W+ ++H+ ++ + L + K+ LS
Sbjct: 226 DVIACINQYNIETQLFIRHPSLWIQKASEHKVTLLYSPNFGYKHFLTFFKPENKKDWDLS 285
Query: 553 SLRMLLVADGANPWSLSSCDQFL 621
+R L+ +GA P S CD+FL
Sbjct: 286 KVR--LIYNGAEPISYELCDEFL 306
>UniRef50_Q1JTE1 Cluster: Type I fatty acid synthase, putative; n=3;
root|Rep: Type I fatty acid synthase, putative -
Toxoplasma gondii RH
Length = 9940
Score = 36.7 bits (81), Expect = 0.59
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 6/65 (9%)
Frame = +1
Query: 109 WPSLHWVSTEKLXXXXXXXXXXXXXAD------ECPAHIEHTSAADGSAMGVIVTRASML 270
W S+HWV T+ + D PA ++ TS + G+ GVIVT S+L
Sbjct: 101 WRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSLL 160
Query: 271 AHCRM 285
+C +
Sbjct: 161 HNCHL 165
>UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA;
n=1; Streptomyces hygroscopicus|Rep: Mannopeptimycin
peptide synthetase MppA - Streptomyces hygroscopicus
Length = 2747
Score = 36.3 bits (80), Expect = 0.78
Identities = 24/100 (24%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACN-YTEGEHMVCVL--DFKRETGL 360
E PA++ +TS + G GV++ +++ R+LS + Y E V L F + +
Sbjct: 157 ENPAYVIYTSGSTGRPKGVVIPHSNV---GRLLSSTAHWYGFDEQDVWPLFHSFAFDVSV 213
Query: 361 WHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
W + ++L+G ++ +P+A+ + +PA ++ ++ + R ++
Sbjct: 214 WE-IWGALLHGGKLVVVPHAVTR-APADFLRLLVEERVTV 251
>UniRef50_A1WAC9 Cluster: AMP-dependent synthetase and ligase; n=3;
Proteobacteria|Rep: AMP-dependent synthetase and ligase
- Acidovorax sp. (strain JS42)
Length = 603
Score = 36.3 bits (80), Expect = 0.78
Identities = 34/148 (22%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHC-RMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
A++++TS + G ++T+++++A+ + + T + L + GL VL
Sbjct: 178 AYLQYTSGSTRFPRGTMITQSAVMANLGAIFNHGFALTADDRFCSWLPHYHDMGLVGIVL 237
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR----DHKEI 543
+ V ++P + P W+ +I+++R +I+ S + L A R D + +
Sbjct: 238 GCMATQRSVDYLPTREFAMRPRLWLKLISRNRCTISY--SPPFGYTLCARRLRPADIEAL 295
Query: 544 SLSSLRMLLV-ADGANPWSLSSCDQFLS 624
LSS R+ V A+ +P SL + L+
Sbjct: 296 DLSSWRIAGVGAEMIHPDSLRQVSEILA 323
>UniRef50_Q2UQJ0 Cluster: Predicted AMP-binding protein; n=6;
Pezizomycotina|Rep: Predicted AMP-binding protein -
Aspergillus oryzae
Length = 1717
Score = 36.3 bits (80), Expect = 0.78
Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNY--------TEGEHMVCVLDFKRET 354
A+IE + A G GV+++ +++ LS + + GE ++ LD +
Sbjct: 296 AYIEFSRAPTGDLRGVVMSHRTIMHQMACLSAMISTVPGSSKVRSHGETIMSYLDPRHGI 355
Query: 355 GLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
G+ VL +V G +++ ++ +P + H+ITK+RA++
Sbjct: 356 GMILGVLLTVYGGHTTVWLEDRAVE-TPGLYAHLITKYRATV 396
>UniRef50_A1YBQ9 Cluster: AmbG; n=1; Sorangium cellulosum|Rep: AmbG
- Polyangium cellulosum (Sorangium cellulosum)
Length = 739
Score = 35.9 bits (79), Expect = 1.0
Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRAS--MLAHCRMLSVACNYTEGEHMVCV--LDFKRETGLWH 366
A +++ S + G+ G IVT AS MLA ++S + G V V L T +
Sbjct: 185 AMLQYASGSTGAPKGTIVTHASLLMLARALLISTSAESPFGRPDVEVTWLPLTHSTAGYG 244
Query: 367 AVLASVLNG-MHVIFIPYALMKVSPASWMHMITKHRAS--IAIVKSRDLHWGLLAT--RD 531
++ + M +I + SPA W+ I++H+ ++ + L W + +T +
Sbjct: 245 LIMKCLTGATMSAWYIAPSAFARSPAIWLRTISRHKGKQVYSVAPNFALDWCVSSTTEAE 304
Query: 532 HKEISLS 552
K++ LS
Sbjct: 305 RKQLDLS 311
>UniRef50_UPI00005579A6 Cluster: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Bacillus
anthracis str. A2012|Rep: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Bacillus anthracis
str. A2012
Length = 412
Score = 35.5 bits (78), Expect = 1.4
Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +1
Query: 187 DECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVA--CNYTEGEHMVCVLDFKRETGL 360
+ PA + +TSA G+ GV+ T S + HC L +A +E + + ++
Sbjct: 100 ENTPAGMCYTSATTGNPKGVVYTHRSTVLHCMALGLADTAALSESDAAMAIVPM-FHVNA 158
Query: 361 WHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKE 540
W A+ G + +P + +P + MI + ++A + G+L ++
Sbjct: 159 WGLPFAATWFGSKQV-LPGPMF--TPKILLEMIQAEKVTLA-AGVPTIWLGVLQELENNS 214
Query: 541 ISLSSLRMLLVADGANPWSL 600
LSS+ +L A P S+
Sbjct: 215 YDLSSMTRILCGXAAAPKSV 234
>UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces fungicidicus|Rep: Nonribosomal peptide
synthetase - Streptomyces fungicidicus
Length = 6943
Score = 35.5 bits (78), Expect = 1.4
Identities = 20/95 (21%), Positives = 47/95 (49%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
PA++ +TS + G GV+V+ S++A + G+ + +W V
Sbjct: 2750 PAYVIYTSGSTGRPKGVVVSHRSVVALFVAAGGVFEFGAGDVWSWFHSLAFDFSVWE-VW 2808
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
++L+G V+ +P+ + + SP ++ ++ + R ++
Sbjct: 2809 GALLHGGRVVVVPFDVSR-SPREFVELLERERVTV 2842
>UniRef50_Q666G1 Cluster: Possible high molecular weight siderophore
biosynthesis protein; n=20; Yersinia|Rep: Possible high
molecular weight siderophore biosynthesis protein -
Yersinia pseudotuberculosis
Length = 3886
Score = 35.1 bits (77), Expect = 1.8
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Frame = +1
Query: 334 LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWG 513
L F + G++ +L +L+G F+P P W+ MI ++A+ + D W
Sbjct: 217 LPFYHDLGMFSGLLLPLLSGGCCNFMPSVHFIAEPFRWLKMINDYQANSG--AAPDFAWD 274
Query: 514 LLAT----RDHKEISLSSLRMLLVADGANP 591
L T +++ LSS++M + +GA P
Sbjct: 275 LCTTMVTDEQIRQLDLSSIKMAM--NGAEP 302
>UniRef50_Q1PSF3 Cluster: Vlm2; n=1; Streptomyces tsusimaensis|Rep:
Vlm2 - Streptomyces tsusimaensis
Length = 2655
Score = 35.1 bits (77), Expect = 1.8
Identities = 24/97 (24%), Positives = 41/97 (42%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHA 369
E PA I TS + G+ GV+ + +++ R Y + + L + GL H+
Sbjct: 333 ESPAVILFTSGSTGTPKGVVQSHVNIVHKQRAAVQHSGYAADDVFLNWLAIEHVVGLIHS 392
Query: 370 VLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
L V + + P W+ + T+HRA+I
Sbjct: 393 HLLPVHLDAAQVHAATDHVLARPTRWLDLATRHRATI 429
>UniRef50_Q01CP6 Cluster: Acyl-CoA synthetase; n=6; Eukaryota|Rep:
Acyl-CoA synthetase - Ostreococcus tauri
Length = 744
Score = 35.1 bits (77), Expect = 1.8
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 2/97 (2%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLS-VACNYTEGEHMV-CVLDFKRETGLWHA 369
PA I +TS + G GV+ L + S + GE +V C D TG +
Sbjct: 345 PAFILYTSGSTGKPKGVVHALGGYLVYAYATSKFVFDLHPGEDIVFCTADLGWITGHSYT 404
Query: 370 VLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
+ +LNG + + W +++ KHR +I
Sbjct: 405 LYGPLLNGCATVLFEGTPTYPNAEIWWNIVDKHRVTI 441
>UniRef50_Q5ZXY3 Cluster: 2-acylglycerophosphoethanolamine
acyltransferase; n=5; Legionella pneumophila|Rep:
2-acylglycerophosphoethanolamine acyltransferase -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 733
Score = 34.7 bits (76), Expect = 2.4
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +1
Query: 214 TSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNG 393
TS ++G GV ++ A++LA+C ++ ++T + + L GL + ++NG
Sbjct: 394 TSGSEGKPKGVALSHANILANCWQMTSRVDFTPRDVLFNSLPIFHCFGLTAGSVLPLVNG 453
Query: 394 MHVIFIPYAL-MKVSP 438
++ F P L KV P
Sbjct: 454 LNCFFYPSPLHYKVIP 469
>UniRef50_UPI000155D219 Cluster: PREDICTED: similar to signaling
molecule LEFTY-A; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to signaling molecule LEFTY-A -
Ornithorhynchus anatinus
Length = 469
Score = 34.3 bits (75), Expect = 3.1
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Frame = +2
Query: 230 DPQWELSLPGLQCWRTVG-CSRWPATTPRVSTW-CAC*TSSARPV 358
D W L PG + VG C R P + PR+S+W C +S+ PV
Sbjct: 393 DDHWILHPPGFEASECVGGCQRLPGSLPRLSSWHCVPTETSSVPV 437
>UniRef50_UPI0000F2C306 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 292
Score = 34.3 bits (75), Expect = 3.1
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = -2
Query: 359 RPVSRLKSSTHTMCSPSV*LQATESIRQCAS-IEALV-TITPIADPSAAEVC 210
+P++ L S HT+CSPS L A + C E+LV T P A P++ +C
Sbjct: 162 QPLTGLVPSDHTLCSPSGTLSALSGLLSCPERPESLVQTSAPPAAPASPSLC 213
>UniRef50_Q9A929 Cluster: Acyl-CoA synthetase; n=4;
Alphaproteobacteria|Rep: Acyl-CoA synthetase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 567
Score = 34.3 bits (75), Expect = 3.1
Identities = 21/99 (21%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLS-VACNYTEGEHMVCVLDFKRETGLWH 366
E P +++ +S + + GV+V +++A+C ++ + + L + GL
Sbjct: 170 EDPCYLQFSSGSTRTPTGVLVRHKALMANCVAITRDGLQVRASDRAISWLPLYHDMGLIG 229
Query: 367 AVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 483
+L+ + M V +P P W+ +I +++A+IA
Sbjct: 230 FLLSPLSCQMTVDLLPTGAFVRRPLLWIDLIGRNKATIA 268
>UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces
filamentosus|Rep: Peptide synthetase 1 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 5830
Score = 34.3 bits (75), Expect = 3.1
Identities = 16/95 (16%), Positives = 50/95 (52%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
PA++ +TS + G GV+++ A+++ S + ++ + + +W +
Sbjct: 4287 PAYVIYTSGSTGRPKGVVISHANVVRLFTACSDSFDFGPDHVWTLFHSYAFDFSVWE-IW 4345
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
++L+G ++ +P+ + + SPA ++ ++ + + ++
Sbjct: 4346 GALLHGGRLVVVPFEVTR-SPAEFLALLAEQQVTL 4379
>UniRef50_Q3W6N9 Cluster: AMP-dependent synthetase and ligase; n=2;
Frankia|Rep: AMP-dependent synthetase and ligase -
Frankia sp. EAN1pec
Length = 562
Score = 34.3 bits (75), Expect = 3.1
Identities = 33/146 (22%), Positives = 67/146 (45%), Gaps = 4/146 (2%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGE-HMVCVLDFKRETGLWHAV 372
PA ++ TS + V+++ +++A+ + + E ++ L + GL A+
Sbjct: 157 PAIVQFTSGTTAAPKSVLISHGNLVANIAAIRERIRHDEVHGRLLSWLPLSHDMGLIGAL 216
Query: 373 LASVLNGM-HVIFIPYALMKVSPASWMHMITKHRASIAI--VKSRDLHWGLLATRDHKEI 543
+ G V+F A SP+SW+ ++RA+I + + + LLA +
Sbjct: 217 AVQLTCGRCDVLFGTPADYLASPSSWLANAARYRATILLGPASAYAMAGRLLAV--GPRL 274
Query: 544 SLSSLRMLLVADGANPWSLSSCDQFL 621
LSS+++ L G P ++ ++FL
Sbjct: 275 DLSSIKVALC--GGEPIEPAAIERFL 298
>UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for
virginiamycin S; n=3; Actinomycetales|Rep: Non ribosomal
peptide synthetase for virginiamycin S - Streptomyces
virginiae
Length = 2671
Score = 34.3 bits (75), Expect = 3.1
Identities = 17/95 (17%), Positives = 46/95 (48%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
PA++ +TS + G GV+VT +++ + + + + +W +
Sbjct: 656 PAYVIYTSGSTGRPKGVVVTHHNVVRLFTAAQQHFGFGPSDVWTLFHSYAFDFSVWE-IW 714
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
+L+G ++ +PY+ + SP +++ ++ + R ++
Sbjct: 715 GPLLHGGRLVVVPYSTSR-SPGAFLDLLAEQRVTV 748
>UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative
non-ribosomal peptide synthetase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 2385
Score = 34.3 bits (75), Expect = 3.1
Identities = 17/95 (17%), Positives = 47/95 (49%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVL 375
PA++ +TS + G+ GV+V+ +++ + + + + +W +
Sbjct: 611 PAYVIYTSGSTGTPKGVVVSHRNVVGLFAATESLFQFGPEDVWTLFHSYAFDFSVWE-LW 669
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
+L+G ++ +P + + SPA ++ ++ +HR ++
Sbjct: 670 GPLLHGGRLVVVPREVTR-SPADFLRLLAEHRVTV 703
>UniRef50_UPI0000E48CA6 Cluster: PREDICTED: similar to gp330
precursor; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to gp330 precursor -
Strongylocentrotus purpuratus
Length = 1796
Score = 33.9 bits (74), Expect = 4.2
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 187 DECPAHIEHT--SAADGSAMGVIVTRASMLAHCRMLSVACNY 306
D C AH+ H S DG+ + +++TR + LAH LS+ NY
Sbjct: 693 DWCDAHLNHIGFSNLDGTNLHLVITRGTPLAHPFALSIFENY 734
>UniRef50_Q28S28 Cluster: AMP-dependent synthetase and ligase; n=9;
Alphaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Jannaschia sp. (strain CCS1)
Length = 494
Score = 33.9 bits (74), Expect = 4.2
Identities = 19/72 (26%), Positives = 37/72 (51%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A + +TS G GV+ +++S+LA +VA T + CVL GL +++
Sbjct: 152 ALLMYTSGTTGKPKGVVHSQSSLLAGGWTTAVAHALTAQDRACCVLPIYHINGLCVSLMG 211
Query: 379 SVLNGMHVIFIP 414
++++G + +P
Sbjct: 212 TLVSGGSALILP 223
>UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1;
Xanthobacter autotrophicus Py2|Rep: Amino acid
adenylation domain - Xanthobacter sp. (strain Py2)
Length = 3208
Score = 33.9 bits (74), Expect = 4.2
Identities = 28/146 (19%), Positives = 63/146 (43%), Gaps = 2/146 (1%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A +++TS + + GV+V+ +++A+ + + + ++ L + GL +L
Sbjct: 176 AFLQYTSGSTSTPKGVMVSHGNLIANEIAIRAGFSIQPDKTILSWLPLYHDMGLIGGLLQ 235
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR-DHKEISLSS 555
+ NG I + P W+ +++ R+ ++ D + + R D ++
Sbjct: 236 PLFNGAACILMSPRHFLARPVRWLEALSRFRSEVS--GGPDFAYRMCVERIDPAQVQGLD 293
Query: 556 LRMLLVA-DGANPWSLSSCDQFLSVF 630
L VA G+ P S+ + F + F
Sbjct: 294 LSSWKVAYSGSEPVRASTMEAFAARF 319
>UniRef50_Q7UGQ5 Cluster: Putative uncharacterized protein; n=1;
Pirellula sp.|Rep: Putative uncharacterized protein -
Rhodopirellula baltica
Length = 486
Score = 33.5 bits (73), Expect = 5.5
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Frame = +1
Query: 409 IPYALMKVSPASWMHMITKHRASIAIVKSRDLHW--GLLATRDHKEISLSSLRML 567
I +L+ V+ A W M + R+ I+ S D HW G L T +E++ LR++
Sbjct: 96 IAASLLFVAAAGWEWMTMQPRSVATIISSTDCHWGTGTLPTTVGQELTTGRLRLI 150
>UniRef50_Q5H0R0 Cluster: Predicted GTPases; n=1; Xanthomonas oryzae
pv. oryzae|Rep: Predicted GTPases - Xanthomonas oryzae
pv. oryzae
Length = 487
Score = 33.5 bits (73), Expect = 5.5
Identities = 35/114 (30%), Positives = 45/114 (39%), Gaps = 5/114 (4%)
Frame = -1
Query: 570 QQHPQRAQRDFLVVACGQQAPVQIAGLNNGDRCPVLGDHVHPRSGADLHQS----VRYED 403
++H +V GQQ AG G C G+H H R H+ R +
Sbjct: 272 RKHATAHPHTVIVARVGQQVEHAAAGAGLGVAC---GEH-HARDPRMDHRHRTHRARLQG 327
Query: 402 DVHPV*DAREDGVPQTGLALEV*HAHHV-LTLGVVAGHREHPTVRQH*SPGNDN 244
DV D G G+A H H + GVVAG E PT QH + G D+
Sbjct: 328 DVERAADQAVIGQAAPGVA----HRHDFGMRAGVVAGDIEVPTFAQHVALGTDD 377
>UniRef50_Q47Q23 Cluster: Putative ortho-succinylbenzoate-CoA
synthetase; n=1; Thermobifida fusca YX|Rep: Putative
ortho-succinylbenzoate-CoA synthetase - Thermobifida
fusca (strain YX)
Length = 391
Score = 33.5 bits (73), Expect = 5.5
Identities = 23/82 (28%), Positives = 39/82 (47%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A + TS + G GV ++ ++LA R + +GE +CVL GL + A
Sbjct: 77 AVVVSTSGSTGQPKGVELSADALLASARASTARIGAQQGEPWLCVLPTAHIAGLQVLLRA 136
Query: 379 SVLNGMHVIFIPYALMKVSPAS 444
+L+ V+F P+ + V A+
Sbjct: 137 RLLDA-PVLFRPFTVEAVQAAA 157
>UniRef50_Q09164 Cluster: Cyclosporine synthetase; n=8; Fungi/Metazoa
group|Rep: Cyclosporine synthetase - Tolypocladium
inflatum
Length = 15281
Score = 33.5 bits (73), Expect = 5.5
Identities = 19/81 (23%), Positives = 37/81 (45%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A++ TS + G GV+V ++ + ++ E HM + + + +W V
Sbjct: 3217 AYVIFTSGSTGRPKGVMVEHRGIVRLTKQTNITSKLPESFHMAHISNLAFDASVWE-VFT 3275
Query: 379 SVLNGMHVIFIPYALMKVSPA 441
++LNG ++ I Y + S A
Sbjct: 3276 TLLNGGTLVCIDYFTLLESTA 3296
>UniRef50_UPI0000E24D6A Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 283
Score = 33.1 bits (72), Expect = 7.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 6/92 (6%)
Frame = +2
Query: 74 RPHPVTWSRFAVGRPYIGCRPRNCRVRRATGSRL------LVRLMNVQRTSNTPPPLTDP 235
RP P+ +R A +P I P+ CR A G +L V L +++ S+ PP + DP
Sbjct: 103 RPPPLNTTRGAQRQPPI---PKGCRTAPARGLQLGFPGAQAVELQSLRSRSSRPPGVGDP 159
Query: 236 QWELSLPGLQCWRTVGCSRWPATTPRVSTWCA 331
+ G R G P P C+
Sbjct: 160 RAPSGREGAPRGREAGIRLSPVAAPPAPRGCS 191
>UniRef50_Q62F82 Cluster: AMP-binding domain protein; n=15;
Burkholderia|Rep: AMP-binding domain protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 588
Score = 33.1 bits (72), Expect = 7.3
Identities = 34/149 (22%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Frame = +1
Query: 202 HIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTE--GEHMVCVLDFKRETGLWHAVL 375
HI+ TS + +++ ++ A+ ++ AC Y++ ++ V L + GL ++L
Sbjct: 167 HIQLTSGSTSHPKAAVISHRNVAANIAGIANACGYSKHAADNTVIWLPLHHDMGL-VSLL 225
Query: 376 ASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGL----LATRDHKEI 543
+ + +P +P W+ I R++IA+ + L + + AT D +
Sbjct: 226 LHLYYRTSLRLMPSMSFVRNPLGWLRRIAHARSTIAVAPTFALRYCVRRFNAATMDGAD- 284
Query: 544 SLSSLRMLLVADGANPWSLSSCDQFLSVF 630
S LR LV GA ++ F S F
Sbjct: 285 -FSHLRTFLV--GAERVDRATLSDFASTF 310
>UniRef50_O67872 Cluster: Acetyl-coenzyme A synthetase; n=5;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Aquifex aeolicus
Length = 510
Score = 33.1 bits (72), Expect = 7.3
Identities = 32/137 (23%), Positives = 52/137 (37%), Gaps = 3/137 (2%)
Frame = +1
Query: 190 ECPAHIEHTSAADGSAMGVIVTRASMLAHCRMLS-VACNYTEGEHMVCVLDFKRETGLWH 366
E P I +TS G GV+ T + S + + E + C D TG +
Sbjct: 257 EDPLFILYTSGTTGKPKGVLHTTGGYMVQTYYTSKIVFDLHEDDIYWCTADIGWITGHSY 316
Query: 367 AVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRD-HKEI 543
V + NG+ + A P W + K+R ++ + + + +
Sbjct: 317 IVYGILANGVTSVITEGAPDYPDPGRWWRYVEKYRVNVFYTAPTAIRMFMRYGEEWPMKY 376
Query: 544 SLSSLRML-LVADGANP 591
LSSLR+L V + NP
Sbjct: 377 DLSSLRILGSVGEPINP 393
>UniRef50_Q5JL80 Cluster: Putative uncharacterized protein
OSJNBa0047D12.24; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OSJNBa0047D12.24 - Oryza sativa subsp. japonica (Rice)
Length = 244
Score = 33.1 bits (72), Expect = 7.3
Identities = 12/35 (34%), Positives = 17/35 (48%)
Frame = +2
Query: 227 TDPQWELSLPGLQCWRTVGCSRWPATTPRVSTWCA 331
TD LSLP + W T + WP ++WC+
Sbjct: 200 TDSTTTLSLPSMMAWPTASIASWPYIHTSEASWCS 234
>UniRef50_Q0CC85 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 635
Score = 33.1 bits (72), Expect = 7.3
Identities = 17/67 (25%), Positives = 34/67 (50%)
Frame = +1
Query: 211 HTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLN 390
+TS GV++ ++++ A L A +YT + ++ +L G+ +A+L VL
Sbjct: 172 YTSGTTNRPKGVLIPQSALTAQASSLLQAWHYTPQDRLLHLLPLHHIHGIVNAILTPVLA 231
Query: 391 GMHVIFI 411
G + F+
Sbjct: 232 GSSIEFM 238
>UniRef50_A1D1R6 Cluster: AMP binding domain protein, putative;
n=18; Pezizomycotina|Rep: AMP binding domain protein,
putative - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 1862
Score = 33.1 bits (72), Expect = 7.3
Identities = 23/103 (22%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYT---------EGEHMVCVLDFKRE 351
A+IE + A G GV+++ +++ L GE ++ LD ++
Sbjct: 450 AYIEFSRAPTGDMRGVVMSHRTIMHQMACLGAIIATVPGSGKSVRPHGETLISYLDPRQG 509
Query: 352 TGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
G+ VL +V G +++ ++ +P + H++TK+RA++
Sbjct: 510 IGMILGVLLTVYGGHTTVWLEDRAVE-TPGLYAHLVTKYRATL 551
>UniRef50_Q5FTV0 Cluster: Acetyl-coenzyme A synthetase; n=1;
Gluconobacter oxydans|Rep: Acetyl-coenzyme A synthetase
- Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 635
Score = 32.7 bits (71), Expect = 9.6
Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 3/127 (2%)
Frame = +1
Query: 196 PAHIEHTSAADGSAMGVIVTRASMLAHCRML-SVACNYTEGEHMVCVLDFKRETGLWHAV 372
P + +TS + G G++ L + ++ EG+ C D TG + V
Sbjct: 245 PLFLLYTSGSTGKPKGIVHGTGGYLVWASYTHELVFDHQEGDIFWCTADIGWITGHTYGV 304
Query: 373 LASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDH--KEIS 546
+LNG ++ P W +I H+ + + L+ D +
Sbjct: 305 YGPLLNGGTILLFEGMPSYPGPGRWWSVIQDHKVTTFYTSPTAIR-ALMREGDEVVQRHD 363
Query: 547 LSSLRML 567
LSSLR+L
Sbjct: 364 LSSLRVL 370
>UniRef50_Q212V5 Cluster: Amino acid adenylation; n=2; cellular
organisms|Rep: Amino acid adenylation - Rhodopseudomonas
palustris (strain BisB18)
Length = 4165
Score = 32.7 bits (71), Expect = 9.6
Identities = 20/94 (21%), Positives = 40/94 (42%)
Frame = +1
Query: 199 AHIEHTSAADGSAMGVIVTRASMLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLA 378
A I++TS + GVI +++++ L + + L + GL VLA
Sbjct: 173 AFIQYTSGSTAEPKGVINRHDTLISNVSFLRCLLWPKDAPVVASWLPLFHDMGLIMGVLA 232
Query: 379 SVLNGMHVIFIPYALMKVSPASWMHMITKHRASI 480
+ G V+++ P W+ + + RA++
Sbjct: 233 PLALGGRVVYMAPGAFVSDPLMWLELAARERAAV 266
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 32.7 bits (71), Expect = 9.6
Identities = 15/36 (41%), Positives = 20/36 (55%)
Frame = -2
Query: 467 CLVIMCIHEAGLTFIRAYGMKMTCIPFRTLARTACH 360
CL++ IHEAGL +RA G+ P +A A H
Sbjct: 3 CLIVQPIHEAGLAALRAAGIAPILCPAPDMATVARH 38
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 757,558,833
Number of Sequences: 1657284
Number of extensions: 15436343
Number of successful extensions: 47068
Number of sequences better than 10.0: 97
Number of HSP's better than 10.0 without gapping: 44795
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 47034
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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