Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--1378
(452 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X65867-2|CAA46697.1| 459|Homo sapiens adenylosuccinate lyase pr... 103 4e-22
X65867-1|CAA46696.1| 484|Homo sapiens adenylosuccinate lyase pr... 103 4e-22
S60710-1|AAC60603.1| 459|Homo sapiens adenylosuccinate lyase pr... 103 4e-22
CR456368-1|CAG30254.1| 425|Homo sapiens ADSL protein. 103 4e-22
BC000253-1|AAH00253.1| 484|Homo sapiens adenylosuccinate lyase ... 103 4e-22
AL022238-2|CAI18983.1| 484|Homo sapiens adenylosuccinate lyase ... 103 4e-22
AF106656-1|AAC83935.1| 484|Homo sapiens adenylosuccinate lyase ... 103 4e-22
AF067854-1|AAC21561.1| 425|Homo sapiens adenylosuccinate lyase ... 103 4e-22
AF067853-1|AAC21560.1| 484|Homo sapiens adenylosuccinate lyase ... 103 4e-22
Z92978-1|CAB07505.1| 669|Homo sapiens amiloride-sensitive epith... 29 7.4
X76180-1|CAA53773.1| 669|Homo sapiens Na+ channel protein protein. 29 7.4
L29007-1|AAA21813.1| 669|Homo sapiens Na+ channel protein. 29 7.4
DQ402522-1|ABD72218.1| 669|Homo sapiens nasal epithelial sodium... 29 7.4
BC071833-1|AAH71833.1| 153|Homo sapiens ORM1-like 3 (S. cerevis... 29 7.4
BC062613-1|AAH62613.1| 669|Homo sapiens sodium channel, nonvolt... 29 7.4
BC017087-1|AAH17087.1| 153|Homo sapiens ORM1-like 3 (S. cerevis... 29 7.4
BC006526-1|AAH06526.2| 711|Homo sapiens SCNN1A protein protein. 29 7.4
AY357943-1|AAQ57273.1| 137|Homo sapiens ORM1-like 3 protein. 29 7.4
AK126559-1|BAC86594.1| 308|Homo sapiens protein ( Homo sapiens ... 29 7.4
AK075212-1|BAC11476.1| 153|Homo sapiens protein ( Homo sapiens ... 29 7.4
AK074811-1|BAC11223.1| 153|Homo sapiens protein ( Homo sapiens ... 29 7.4
AF395708-1|AAM43507.1| 153|Homo sapiens ORMDL3 protein. 29 7.4
AF373102-1|AAN76522.1| 153|Homo sapiens unknown protein. 29 7.4
AF373101-1|AAN76521.1| 153|Homo sapiens unknown protein. 29 7.4
AF060913-1|AAD28355.1| 669|Homo sapiens epithelial sodium chann... 29 7.4
>X65867-2|CAA46697.1| 459|Homo sapiens adenylosuccinate lyase
protein.
Length = 459
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 37 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 96
Query: 435 IVLKN 449
I+L+N
Sbjct: 97 IILRN 101
Score = 46.8 bits (106), Expect = 3e-05
Identities = 20/36 (55%), Positives = 28/36 (77%)
Frame = +1
Query: 148 MQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
M + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 1 MCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 36
>X65867-1|CAA46696.1| 484|Homo sapiens adenylosuccinate lyase
protein.
Length = 484
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>S60710-1|AAC60603.1| 459|Homo sapiens adenylosuccinate lyase
protein.
Length = 459
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 37 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 96
Query: 435 IVLKN 449
I+L+N
Sbjct: 97 IILRN 101
Score = 46.8 bits (106), Expect = 3e-05
Identities = 20/36 (55%), Positives = 28/36 (77%)
Frame = +1
Query: 148 MQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
M + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 1 MCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 36
>CR456368-1|CAG30254.1| 425|Homo sapiens ADSL protein.
Length = 425
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>BC000253-1|AAH00253.1| 484|Homo sapiens adenylosuccinate lyase
protein.
Length = 484
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>AL022238-2|CAI18983.1| 484|Homo sapiens adenylosuccinate lyase
protein.
Length = 484
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>AF106656-1|AAC83935.1| 484|Homo sapiens adenylosuccinate lyase
protein.
Length = 484
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>AF067854-1|AAC21561.1| 425|Homo sapiens adenylosuccinate lyase
protein.
Length = 425
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>AF067853-1|AAC21560.1| 484|Homo sapiens adenylosuccinate lyase
protein.
Length = 484
Score = 103 bits (246), Expect = 4e-22
Identities = 46/65 (70%), Positives = 54/65 (83%)
Frame = +3
Query: 255 IAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDL 434
I E+++ + +IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDL
Sbjct: 62 IQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDL 121
Query: 435 IVLKN 449
I+L+N
Sbjct: 122 IILRN 126
Score = 68.5 bits (160), Expect = 1e-11
Identities = 30/50 (60%), Positives = 41/50 (82%)
Frame = +1
Query: 106 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQ 255
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ Q
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQ 61
>Z92978-1|CAB07505.1| 669|Homo sapiens amiloride-sensitive
epithelial sodium channel alpha subunit protein.
Length = 669
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 440 QNVEYCDYRKHSSWGYCYYKLQVDFS 465
>X76180-1|CAA53773.1| 669|Homo sapiens Na+ channel protein protein.
Length = 669
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 440 QNVEYCDYRKHSSWGYCYYKLQVDFS 465
>L29007-1|AAA21813.1| 669|Homo sapiens Na+ channel protein.
Length = 669
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 440 QNVEYCDYRKHSSWGYCYYKLQVDFS 465
>DQ402522-1|ABD72218.1| 669|Homo sapiens nasal epithelial sodium
channel alpha subunit protein.
Length = 669
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 440 QNVEYCDYRKHSSWGYCYYKLQVDFS 465
>BC071833-1|AAH71833.1| 153|Homo sapiens ORM1-like 3 (S.
cerevisiae) protein.
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>BC062613-1|AAH62613.1| 669|Homo sapiens sodium channel,
nonvoltage-gated 1 alpha protein.
Length = 669
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 440 QNVEYCDYRKHSSWGYCYYKLQVDFS 465
>BC017087-1|AAH17087.1| 153|Homo sapiens ORM1-like 3 (S.
cerevisiae) protein.
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>BC006526-1|AAH06526.2| 711|Homo sapiens SCNN1A protein protein.
Length = 711
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 482 QNVEYCDYRKHSSWGYCYYKLQVDFS 507
>AY357943-1|AAQ57273.1| 137|Homo sapiens ORM1-like 3 protein.
Length = 137
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 78 QFTASRKFLTITPIVLYF 95
>AK126559-1|BAC86594.1| 308|Homo sapiens protein ( Homo sapiens
cDNA FLJ44595 fis, clone BLADE2004849. ).
Length = 308
Score = 29.1 bits (62), Expect = 7.4
Identities = 14/29 (48%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Frame = +1
Query: 346 STRSARGVPS-PRPSYTWEPRRATSETTP 429
S R+ RG+PS P P+ W PRR E+ P
Sbjct: 278 SRRADRGLPSAPLPTGGWRPRRLRVESFP 306
>AK075212-1|BAC11476.1| 153|Homo sapiens protein ( Homo sapiens
cDNA FLJ90731 fis, clone PLACE1010078, highly similar to
ORM1-like 3. ).
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>AK074811-1|BAC11223.1| 153|Homo sapiens protein ( Homo sapiens
cDNA FLJ90330 fis, clone NT2RP2001956, highly similar to
ORM1-like 3. ).
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>AF395708-1|AAM43507.1| 153|Homo sapiens ORMDL3 protein.
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>AF373102-1|AAN76522.1| 153|Homo sapiens unknown protein.
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>AF373101-1|AAN76521.1| 153|Homo sapiens unknown protein.
Length = 153
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = -3
Query: 198 EFTPSRKFLLVTEIVLHF 145
+FT SRKFL +T IVL+F
Sbjct: 94 QFTASRKFLTITPIVLYF 111
>AF060913-1|AAD28355.1| 669|Homo sapiens epithelial sodium channel
alpha-subunit protein.
Length = 669
Score = 29.1 bits (62), Expect = 7.4
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 88 QNTEYCNYRSPLSTRYASKEMQYNFS 165
QN EYC+YR S Y ++Q +FS
Sbjct: 440 QNVEYCDYRKHSSWGYCYYKLQVDFS 465
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 67,157,457
Number of Sequences: 237096
Number of extensions: 1385118
Number of successful extensions: 3591
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 3480
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3591
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 3758237868
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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