Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--1041
(654 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VA70 Cluster: Neutral ceramidase precursor; n=8; Dipt... 103 4e-21
UniRef50_Q7QI06 Cluster: ENSANGP00000018598; n=4; Endopterygota|... 102 9e-21
UniRef50_Q095I8 Cluster: Neutral/alkaline nonlysosomal ceramidas... 69 7e-11
UniRef50_Q9I596 Cluster: Neutral ceramidase precursor; n=6; Pseu... 69 1e-10
UniRef50_Q55G11 Cluster: Neutral ceramidase B precursor; n=2; Di... 66 9e-10
UniRef50_Q304B9 Cluster: Neutral ceramidase precursor; n=11; Mag... 62 1e-08
UniRef50_UPI0000E4A628 Cluster: PREDICTED: similar to mitochondr... 59 1e-07
UniRef50_A7NVS3 Cluster: Chromosome chr18 scaffold_1, whole geno... 58 2e-07
UniRef50_Q0V2P3 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_A1D3X9 Cluster: Neutral/alkaline nonlysosomal ceramidas... 55 1e-06
UniRef50_A6GSB0 Cluster: Alkaline ceramidase; n=1; Limnobacter s... 54 2e-06
UniRef50_Q9FIL4 Cluster: Neutral ceramidase; n=3; Arabidopsis th... 54 2e-06
UniRef50_O06769 Cluster: POSSIBLE HYDROLASE; n=6; Mycobacterium ... 54 3e-06
UniRef50_A0Z3M0 Cluster: Putative uncharacterized protein; n=2; ... 54 3e-06
UniRef50_Q4PHP6 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q4JV90 Cluster: Putative N-acylsphingosine amidohydrola... 52 9e-06
UniRef50_Q8KNN6 Cluster: Alkaline ceramidase; n=1; Dermatophilus... 52 9e-06
UniRef50_Q7S6I3 Cluster: Putative uncharacterized protein NCU047... 52 9e-06
UniRef50_Q9NR71-2 Cluster: Isoform 2 of Q9NR71 ; n=4; Catarrhini... 51 2e-05
UniRef50_Q9NR71 Cluster: Neutral ceramidase (EC 3.5.1.23) (NCDas... 51 2e-05
UniRef50_Q7S802 Cluster: Putative uncharacterized protein NCU011... 50 4e-05
UniRef50_A5WHU1 Cluster: Neutral/alkaline nonlysosomal ceramidas... 50 5e-05
UniRef50_A3YEJ8 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_A1ZDK8 Cluster: Alkaline ceramidase; n=1; Microscilla m... 47 5e-04
UniRef50_A4FEG6 Cluster: Possible hydrolase; n=3; Actinomycetale... 46 8e-04
UniRef50_A1IDX4 Cluster: Putative uncharacterized protein precur... 40 0.039
UniRef50_UPI0000E46234 Cluster: PREDICTED: hypothetical protein,... 40 0.052
UniRef50_UPI0000E4707B Cluster: PREDICTED: similar to mitochondr... 38 0.16
UniRef50_Q01NW5 Cluster: Putative uncharacterized protein precur... 35 1.5
UniRef50_Q0DIN1 Cluster: Os05g0375600 protein; n=4; Oryza sativa... 34 3.4
UniRef50_Q4WS57 Cluster: Leucine carboxyl methyltransferase 1; n... 34 3.4
UniRef50_A6CDU4 Cluster: Putative uncharacterized protein; n=1; ... 33 4.5
UniRef50_Q5DQI8 Cluster: EitB; n=28; Proteobacteria|Rep: EitB - ... 33 6.0
UniRef50_A6SE22 Cluster: Predicted protein; n=1; Botryotinia fuc... 33 6.0
UniRef50_Q24FA2 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_Q6C3C4 Cluster: Yarrowia lipolytica chromosome F of str... 33 7.9
>UniRef50_Q9VA70 Cluster: Neutral ceramidase precursor; n=8;
Diptera|Rep: Neutral ceramidase precursor - Drosophila
melanogaster (Fruit fly)
Length = 704
Score = 103 bits (247), Expect = 4e-21
Identities = 55/137 (40%), Positives = 77/137 (56%)
Frame = +3
Query: 243 SKRSIMLYAWCVLACVTAADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSR 422
SK + + + C + +VG G AD+TGPP EI FMGYA ++Q+G GIH R F+R
Sbjct: 4 SKMAFLAFLAVSFLCGLVSATYKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFAR 63
Query: 423 AFVIEDNSGDTVKRLVFVSVDAAMMGHGVGKR**DGCRSALA*STTRIM*SSAAPTLTPL 602
AFV+ED G+ R+ FVS DA MMG+G+ + ++ + +
Sbjct: 64 AFVVEDEKGN---RVAFVSADAGMMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGA 120
Query: 603 PGGFLMDFLFDLPILGF 653
PGGFLM L+D+ ILGF
Sbjct: 121 PGGFLMHLLYDISILGF 137
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/39 (58%), Positives = 28/39 (71%)
Frame = +2
Query: 509 RKEVIRRLQKRFGVIYNEDNVIISGTHTHSTSWRIPDGF 625
++EVI+RLQ R+G IY+ DNV ISGTHTH P GF
Sbjct: 90 KREVIKRLQARYGNIYHNDNVAISGTHTHGA----PGGF 124
>UniRef50_Q7QI06 Cluster: ENSANGP00000018598; n=4;
Endopterygota|Rep: ENSANGP00000018598 - Anopheles
gambiae str. PEST
Length = 709
Score = 102 bits (244), Expect = 9e-21
Identities = 64/137 (46%), Positives = 77/137 (56%), Gaps = 1/137 (0%)
Frame = +3
Query: 246 KRSIMLYAWCVLA-CVTAADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSR 422
K S + A VLA + A RVG G AD TGP EI FMGYAQ+ Q G GIHLRQ++R
Sbjct: 12 KWSKLRMALAVLALAIGTTGAYRVGVGRADCTGPSVEITFMGYAQVTQRGTGIHLRQYAR 71
Query: 423 AFVIEDNSGDTVKRLVFVSVDAAMMGHGVGKR**DGCRSALA*STTRIM*SSAAPTLTPL 602
++VIED +G R+VFVSVDA MMGH V + + T +
Sbjct: 72 SYVIEDENG---TRVVFVSVDAGMMGHAVKRDVLAVLQKKYGELYTHANVVISGTHTHST 128
Query: 603 PGGFLMDFLFDLPILGF 653
PGGFLM L+DL LGF
Sbjct: 129 PGGFLMYLLYDLTSLGF 145
>UniRef50_Q095I8 Cluster: Neutral/alkaline nonlysosomal ceramidase
superfamily; n=2; Cystobacterineae|Rep: Neutral/alkaline
nonlysosomal ceramidase superfamily - Stigmatella
aurantiaca DW4/3-1
Length = 689
Score = 69.3 bits (162), Expect = 7e-11
Identities = 45/117 (38%), Positives = 64/117 (54%)
Frame = +3
Query: 303 ALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSV 482
A +VG+GI D+TGP AE+ MGYA ++Q GIH R +RAFV+ S KR+ FVS
Sbjct: 49 AFQVGSGIYDITGPAAELGMMGYAMIDQKTAGIHQRLRARAFVVA--SPCNGKRVAFVSA 106
Query: 483 DAAMMGHGVGKR**DGCRSALA*STTRIM*SSAAPTLTPLPGGFLMDFLFDLPILGF 653
DA + GV ++ + ++ T +A PGGF L++L ILG+
Sbjct: 107 DAGQIFQGVRQQVVERLKARFGNLYTDENVVLSATHTHSGPGGFSHYALYNLTILGY 163
>UniRef50_Q9I596 Cluster: Neutral ceramidase precursor; n=6;
Pseudomonas aeruginosa|Rep: Neutral ceramidase precursor
- Pseudomonas aeruginosa
Length = 670
Score = 68.5 bits (160), Expect = 1e-10
Identities = 49/132 (37%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Frame = +3
Query: 273 CVLACVTA---ADAL--RVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIE 437
CVL ++ AD L R G G AD+TG AE+ MGY+ LEQ GIH+RQ++RAFVIE
Sbjct: 13 CVLLALSMPARADDLPYRFGLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIE 72
Query: 438 DNSGDTVKRLVFVSVDAAMMGHGVGKR**DGCRSALA*STTRIM*SSAAPTLTPLPGGFL 617
+ + +RLV+V+ D M+ V + ++ AA PGGF
Sbjct: 73 EAASG--RRLVYVNTDLGMIFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFS 130
Query: 618 MDFLFDLPILGF 653
+++L +LGF
Sbjct: 131 HYAMYNLSVLGF 142
Score = 34.7 bits (76), Expect = 2.0
Identities = 12/28 (42%), Positives = 23/28 (82%)
Frame = +2
Query: 515 EVIRRLQKRFGVIYNEDNVIISGTHTHS 598
+V+ RL+ ++ +Y+E+NV+++ THTHS
Sbjct: 97 KVLARLKAKYPGVYDENNVMLAATHTHS 124
>UniRef50_Q55G11 Cluster: Neutral ceramidase B precursor; n=2;
Dictyostelium discoideum|Rep: Neutral ceramidase B
precursor - Dictyostelium discoideum (Slime mold)
Length = 718
Score = 65.7 bits (153), Expect = 9e-10
Identities = 32/63 (50%), Positives = 44/63 (69%)
Frame = +3
Query: 309 RVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDA 488
++GAGI D+TG AE+ MGYA Q+G GIH RQ +RAFV D++G+ R V+VS D+
Sbjct: 47 QIGAGIYDITGASAEVNLMGYANPLQVGAGIHFRQRARAFVFVDSNGN---RAVYVSTDS 103
Query: 489 AMM 497
M+
Sbjct: 104 CMI 106
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/28 (57%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +2
Query: 518 VIRRLQKRFGV-IYNEDNVIISGTHTHS 598
V+ LQ FG +Y E NV++SGTHTHS
Sbjct: 114 VVELLQDIFGPNVYTEANVLLSGTHTHS 141
>UniRef50_Q304B9 Cluster: Neutral ceramidase precursor; n=11;
Magnoliophyta|Rep: Neutral ceramidase precursor -
Arabidopsis thaliana (Mouse-ear cress)
Length = 757
Score = 61.7 bits (143), Expect = 1e-08
Identities = 29/64 (45%), Positives = 42/64 (65%)
Frame = +3
Query: 303 ALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSV 482
A +G G D+TGP A++ MGYA +QI GIH R +RAF++ + G+ R+VFV++
Sbjct: 25 AYLIGVGSYDITGPAADVNMMGYANSDQIASGIHFRLRARAFIVAEPQGN---RVVFVNL 81
Query: 483 DAAM 494
DA M
Sbjct: 82 DACM 85
Score = 38.3 bits (85), Expect = 0.16
Identities = 15/28 (53%), Positives = 21/28 (75%)
Frame = +2
Query: 515 EVIRRLQKRFGVIYNEDNVIISGTHTHS 598
+V+ RL+ R+G +Y E NV ISG HTH+
Sbjct: 93 KVLERLKARYGELYTEKNVAISGIHTHA 120
>UniRef50_UPI0000E4A628 Cluster: PREDICTED: similar to mitochondrial
ceramidase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to mitochondrial ceramidase -
Strongylocentrotus purpuratus
Length = 340
Score = 58.8 bits (136), Expect = 1e-07
Identities = 39/97 (40%), Positives = 48/97 (49%)
Frame = +3
Query: 363 MGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDAAMMGHGVGKR**DGCRSA 542
MGYA Q GI +RQFSRAFVI D+ G+ KR VFVS+DA M GV ++A
Sbjct: 1 MGYANPSQTAGGISIRQFSRAFVIADSKGE--KRFVFVSIDAGMQDQGVTLEVISRLKTA 58
Query: 543 LA*STTRIM*SSAAPTLTPLPGGFLMDFLFDLPILGF 653
+ + GFL LFD+ LGF
Sbjct: 59 YGGLYNETNVAISGTHSHSGTAGFLQFVLFDVTSLGF 95
Score = 41.9 bits (94), Expect = 0.013
Identities = 18/28 (64%), Positives = 22/28 (78%)
Frame = +2
Query: 515 EVIRRLQKRFGVIYNEDNVIISGTHTHS 598
EVI RL+ +G +YNE NV ISGTH+HS
Sbjct: 50 EVISRLKTAYGGLYNETNVAISGTHSHS 77
>UniRef50_A7NVS3 Cluster: Chromosome chr18 scaffold_1, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr18 scaffold_1, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 706
Score = 57.6 bits (133), Expect = 2e-07
Identities = 35/114 (30%), Positives = 56/114 (49%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDAA 491
+G G D+TGP A++ MGYA +EQ GIH R +RAF++ + G R FV++DA
Sbjct: 32 IGIGSYDMTGPAADVNMMGYANIEQHSAGIHFRLRARAFIVAE--GPQGVRFAFVNLDAG 89
Query: 492 MMGHGVGKR**DGCRSALA*STTRIM*SSAAPTLTPLPGGFLMDFLFDLPILGF 653
M V + + +S + + PGG+L +++ + GF
Sbjct: 90 MASQLVTIKVLERLKSRYGNLYNEDNLAISGTHTHAGPGGYLQYYVYSITTAGF 143
>UniRef50_Q0V2P3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 716
Score = 57.6 bits (133), Expect = 2e-07
Identities = 27/58 (46%), Positives = 38/58 (65%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVD 485
VG G AD+TGP E+ MGYA QIG G+ R +SRAF++ N D +R+V++ +D
Sbjct: 69 VGVGKADITGPVVELNLMGYANSSQIGTGLRQRIYSRAFIV-GNPSDPSERIVYMVLD 125
>UniRef50_A1D3X9 Cluster: Neutral/alkaline nonlysosomal ceramidase,
putative; n=10; Pezizomycotina|Rep: Neutral/alkaline
nonlysosomal ceramidase, putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 764
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/59 (42%), Positives = 37/59 (62%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDA 488
+GAG AD+TGP E+A GYA L+QIG G+ R +SR+F+ N +++ +DA
Sbjct: 61 LGAGKADITGPVVEVALSGYAMLDQIGTGLRQRIYSRSFIFA-NPNQPDDTFIYIVIDA 118
>UniRef50_A6GSB0 Cluster: Alkaline ceramidase; n=1; Limnobacter sp.
MED105|Rep: Alkaline ceramidase - Limnobacter sp. MED105
Length = 820
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/69 (43%), Positives = 37/69 (53%)
Frame = +3
Query: 303 ALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSV 482
A +G GI D+TGP A MGY G+H RQFSRA+VI S R+V+V
Sbjct: 101 AFTMGTGIVDITGPAAGSVMMGYESPTHASLGLHTRQFSRAYVI--GSPCNGNRVVYVVN 158
Query: 483 DAAMMGHGV 509
D M+ H V
Sbjct: 159 DLGMIFHAV 167
>UniRef50_Q9FIL4 Cluster: Neutral ceramidase; n=3; Arabidopsis
thaliana|Rep: Neutral ceramidase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 705
Score = 54.4 bits (125), Expect = 2e-06
Identities = 21/54 (38%), Positives = 34/54 (62%)
Frame = +3
Query: 279 LACVTAADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIED 440
L C+ + +G G D+TGP A++ MGYA +EQ+ G+H R +RAF++ +
Sbjct: 20 LTCIFSDSDYLMGLGSYDITGPAADVNMMGYANMEQVASGVHFRLRARAFIVAE 73
>UniRef50_O06769 Cluster: POSSIBLE HYDROLASE; n=6; Mycobacterium
tuberculosis complex|Rep: POSSIBLE HYDROLASE -
Mycobacterium tuberculosis
Length = 637
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/57 (47%), Positives = 35/57 (61%)
Frame = +3
Query: 306 LRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFV 476
L VG GIAD+TG A+ +GY + +Q GIH R SRAFV D+S D RL+ +
Sbjct: 2 LSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLI 58
Score = 36.3 bits (80), Expect = 0.64
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +2
Query: 512 KEVIRRLQKRFGVIYNEDNVIISGTHTHS 598
+EV+RRL +G Y+E N +I+ THTH+
Sbjct: 71 EEVLRRLADLYGDTYSEQNTLITATHTHA 99
>UniRef50_A0Z3M0 Cluster: Putative uncharacterized protein; n=2;
unclassified Gammaproteobacteria (miscellaneous)|Rep:
Putative uncharacterized protein - marine gamma
proteobacterium HTCC2080
Length = 688
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/64 (39%), Positives = 38/64 (59%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDAA 491
+G G+ D+TGP + G+ + +QI G+H+R SRAF+ S + +RLVFVS D
Sbjct: 48 IGRGMVDITGPEVGMPLWGFGRPDQISEGVHIRLRSRAFITAQAS-NPKQRLVFVSADLG 106
Query: 492 MMGH 503
+ H
Sbjct: 107 SIDH 110
Score = 40.3 bits (90), Expect = 0.039
Identities = 17/28 (60%), Positives = 21/28 (75%)
Frame = +2
Query: 515 EVIRRLQKRFGVIYNEDNVIISGTHTHS 598
EV+ RLQ R+G Y +NVIIS THTH+
Sbjct: 115 EVVERLQLRYGPTYTLENVIISATHTHA 142
>UniRef50_Q4PHP6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 765
Score = 53.6 bits (123), Expect = 4e-06
Identities = 26/61 (42%), Positives = 35/61 (57%)
Frame = +3
Query: 282 ACVTAADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVK 461
A V++ + G GI DVTGP E+ MGYA L Q G+H+R SRAF++ + T
Sbjct: 98 ATVSSDSPVVFGLGIGDVTGPIVEVNMMGYASLPQTNTGLHIRLRSRAFIVGSSDAPTFF 157
Query: 462 R 464
R
Sbjct: 158 R 158
Score = 33.5 bits (73), Expect = 4.5
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +2
Query: 488 CDDGTWSRKEVIRRLQKRFGVIYNEDNVIISGTHTHS 598
C T RK ++ +L++++ +Y E NV GTH+H+
Sbjct: 186 CMGDTALRKAIVDQLREKYPGVYGERNVAFVGTHSHA 222
>UniRef50_Q4JV90 Cluster: Putative N-acylsphingosine amidohydrolase
precursor; n=1; Corynebacterium jeikeium K411|Rep:
Putative N-acylsphingosine amidohydrolase precursor -
Corynebacterium jeikeium (strain K411)
Length = 692
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/72 (40%), Positives = 40/72 (55%)
Frame = +3
Query: 282 ACVTAADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVK 461
A ++ +VG G+AD+TG P GYA EQ GI RQ++RAF+ D + D
Sbjct: 52 AANSSGGGFQVGRGLADMTGEPWGAGMFGYAVDEQKTVGIQRRQYARAFIFVDANRDN-S 110
Query: 462 RLVFVSVDAAMM 497
RLV V+ D +M
Sbjct: 111 RLVHVTCDVGLM 122
Score = 42.7 bits (96), Expect = 0.007
Identities = 15/27 (55%), Positives = 24/27 (88%)
Frame = +2
Query: 515 EVIRRLQKRFGVIYNEDNVIISGTHTH 595
EV+RRL+++FG +YN+ NV+++ THTH
Sbjct: 129 EVLRRLKEKFGDLYNQSNVLLAATHTH 155
>UniRef50_Q8KNN6 Cluster: Alkaline ceramidase; n=1; Dermatophilus
congolensis|Rep: Alkaline ceramidase - Dermatophilus
congolensis
Length = 705
Score = 52.4 bits (120), Expect = 9e-06
Identities = 26/65 (40%), Positives = 39/65 (60%)
Frame = +3
Query: 303 ALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSV 482
A VG+G+ D+TG AE +GYA +++ G+H+R +SRAFV+ D KR+ V+
Sbjct: 49 AYLVGSGMYDITGAAAETGMLGYAASQEV-DGLHMRLYSRAFVVADQKSG--KRVAMVTT 105
Query: 483 DAAMM 497
D M
Sbjct: 106 DMGAM 110
Score = 33.9 bits (74), Expect = 3.4
Identities = 13/26 (50%), Positives = 19/26 (73%)
Frame = +2
Query: 518 VIRRLQKRFGVIYNEDNVIISGTHTH 595
V+ +LQ++FG Y NV+I+ THTH
Sbjct: 118 VVAKLQQKFGDKYTPKNVLIAATHTH 143
>UniRef50_Q7S6I3 Cluster: Putative uncharacterized protein
NCU04721.1; n=5; Pezizomycotina|Rep: Putative
uncharacterized protein NCU04721.1 - Neurospora crassa
Length = 780
Score = 52.4 bits (120), Expect = 9e-06
Identities = 24/62 (38%), Positives = 36/62 (58%)
Frame = +3
Query: 300 DALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVS 479
D +G G ADVTGP E+ GYA Q+G G+ R +SR F+I + + R+V++
Sbjct: 73 DKYLIGVGKADVTGPVVEVGLGGYADTSQVGSGLRQRLYSRTFIIGETK-NPKNRVVYIV 131
Query: 480 VD 485
+D
Sbjct: 132 LD 133
>UniRef50_Q9NR71-2 Cluster: Isoform 2 of Q9NR71 ; n=4;
Catarrhini|Rep: Isoform 2 of Q9NR71 - Homo sapiens
(Human)
Length = 745
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDAA 491
+G G AD TG A+I MGY + Q GI R +SRAF++ + G R VFVS+D
Sbjct: 104 IGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGS--NRTVFVSIDIG 161
Query: 492 MM 497
M+
Sbjct: 162 MV 163
Score = 47.6 bits (108), Expect = 3e-04
Identities = 19/30 (63%), Positives = 24/30 (80%)
Frame = +2
Query: 509 RKEVIRRLQKRFGVIYNEDNVIISGTHTHS 598
R EV+ RLQ ++G +Y DNVI+SGTHTHS
Sbjct: 168 RLEVLNRLQSKYGSLYRRDNVILSGTHTHS 197
>UniRef50_Q9NR71 Cluster: Neutral ceramidase (EC 3.5.1.23) (NCDase)
(N-CDase) (Acylsphingosine deacylase 2)
(N-acylsphingosine amidohydrolase 2) (Non-lysosomal
ceramidase) (BCDase) (LCDase) (hCD) [Contains: Neutral
ceramidase soluble form]; n=30; Euteleostomi|Rep:
Neutral ceramidase (EC 3.5.1.23) (NCDase) (N-CDase)
(Acylsphingosine deacylase 2) (N-acylsphingosine
amidohydrolase 2) (Non-lysosomal ceramidase) (BCDase)
(LCDase) (hCD) [Contains: Neutral ceramidase soluble
form] - Homo sapiens (Human)
Length = 780
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDAA 491
+G G AD TG A+I MGY + Q GI R +SRAF++ + G R VFVS+D
Sbjct: 104 IGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGS--NRTVFVSIDIG 161
Query: 492 MM 497
M+
Sbjct: 162 MV 163
Score = 47.6 bits (108), Expect = 3e-04
Identities = 19/30 (63%), Positives = 24/30 (80%)
Frame = +2
Query: 509 RKEVIRRLQKRFGVIYNEDNVIISGTHTHS 598
R EV+ RLQ ++G +Y DNVI+SGTHTHS
Sbjct: 168 RLEVLNRLQSKYGSLYRRDNVILSGTHTHS 197
>UniRef50_Q7S802 Cluster: Putative uncharacterized protein
NCU01168.1; n=8; Pezizomycotina|Rep: Putative
uncharacterized protein NCU01168.1 - Neurospora crassa
Length = 1425
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/53 (45%), Positives = 32/53 (60%)
Frame = +3
Query: 276 VLACVTAADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVI 434
V C T L +G G D+TGP EI MGYA +Q+G G+ R +SRAF++
Sbjct: 101 VSTCATDTQYL-LGVGKGDITGPVVEINLMGYADPKQLGTGLRQRLYSRAFIV 152
>UniRef50_A5WHU1 Cluster: Neutral/alkaline nonlysosomal ceramidase
precursor; n=1; Psychrobacter sp. PRwf-1|Rep:
Neutral/alkaline nonlysosomal ceramidase precursor -
Psychrobacter sp. PRwf-1
Length = 743
Score = 50.0 bits (114), Expect = 5e-05
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVK------RLVF 473
+GA AD+TG AE GYA +Q+ GI+ R ++ AF+I DN D+ + R+V+
Sbjct: 81 LGAAQADITGAAAETGMFGYAA-QQVAQGINDRLYAHAFIIVDNQADSAQTTQNSARIVY 139
Query: 474 VSVDAAMMGHGV 509
VS D M + V
Sbjct: 140 VSADMGAMFNAV 151
>UniRef50_A3YEJ8 Cluster: Putative uncharacterized protein; n=1;
Marinomonas sp. MED121|Rep: Putative uncharacterized
protein - Marinomonas sp. MED121
Length = 708
Score = 47.6 bits (108), Expect = 3e-04
Identities = 24/58 (41%), Positives = 34/58 (58%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVD 485
+G+GI D+TGP A+ +GY Q GI R +SRAF + + D K ++FVS D
Sbjct: 43 IGSGIYDITGPAADRGMVGYGDTGQTTQGIFTRLWSRAFTLGSAADD--KFVIFVSAD 98
>UniRef50_A1ZDK8 Cluster: Alkaline ceramidase; n=1; Microscilla
marina ATCC 23134|Rep: Alkaline ceramidase - Microscilla
marina ATCC 23134
Length = 649
Score = 46.8 bits (106), Expect = 5e-04
Identities = 26/58 (44%), Positives = 35/58 (60%)
Frame = +3
Query: 312 VGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVD 485
+G GI DVTG AE GYAQL GI RQ++RA+V+++ +G VFV +D
Sbjct: 15 IGVGIYDVTGQIAETNCGGYAQLLHRNKGIRDRQYARAYVMQEPNGSPA---VFVCID 69
Score = 35.9 bits (79), Expect = 0.85
Identities = 13/29 (44%), Positives = 23/29 (79%)
Frame = +2
Query: 518 VIRRLQKRFGVIYNEDNVIISGTHTHSTS 604
VI++L+ ++G ++++ NV+IS THTH S
Sbjct: 81 VIQKLKSKYGGLFSDANVVISATHTHLAS 109
>UniRef50_A4FEG6 Cluster: Possible hydrolase; n=3;
Actinomycetales|Rep: Possible hydrolase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 681
Score = 46.0 bits (104), Expect = 8e-04
Identities = 25/65 (38%), Positives = 35/65 (53%)
Frame = +3
Query: 315 GAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVFVSVDAAM 494
G GI+D TG AE MGY + +Q G+H R R+FVI G R++ + VD+ M
Sbjct: 43 GRGISDATGEVAECGMMGYGRFDQQAAGLHTRLRVRSFVIATPDGG--DRVLLIVVDSPM 100
Query: 495 MGHGV 509
+ V
Sbjct: 101 IFESV 105
Score = 38.7 bits (86), Expect = 0.12
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +2
Query: 518 VIRRLQKRFGVIYNEDNVIISGTHTHS 598
V+RRL +RFG Y E NV+I+ THTH+
Sbjct: 109 VLRRLGERFGDRYTEQNVLITATHTHA 135
>UniRef50_A1IDX4 Cluster: Putative uncharacterized protein
precursor; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: Putative uncharacterized protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 677
Score = 40.3 bits (90), Expect = 0.039
Identities = 22/70 (31%), Positives = 34/70 (48%)
Frame = +3
Query: 294 AADALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNSGDTVKRLVF 473
A L G D+T PP IA GY+ + ++ G R ++RA IED++G V +
Sbjct: 42 AVAGLSAGLARVDITPPPG-IATAGYSLMAEVSRGFRTRLYARAVYIEDSAGGKVALVAC 100
Query: 474 VSVDAAMMGH 503
+ A + H
Sbjct: 101 DFLSGARLLH 110
>UniRef50_UPI0000E46234 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 235
Score = 39.9 bits (89), Expect = 0.052
Identities = 17/27 (62%), Positives = 21/27 (77%)
Frame = +2
Query: 518 VIRRLQKRFGVIYNEDNVIISGTHTHS 598
VI RL+ +G +YNE NV ISGTH+HS
Sbjct: 1 VISRLKTAYGGLYNETNVAISGTHSHS 27
>UniRef50_UPI0000E4707B Cluster: PREDICTED: similar to mitochondrial
ceramidase, partial; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to mitochondrial
ceramidase, partial - Strongylocentrotus purpuratus
Length = 428
Score = 38.3 bits (85), Expect = 0.16
Identities = 15/28 (53%), Positives = 21/28 (75%)
Frame = +2
Query: 515 EVIRRLQKRFGVIYNEDNVIISGTHTHS 598
+V +L+ +G YNE NV++SGTHTHS
Sbjct: 51 DVFEQLRGLYGERYNEQNVVLSGTHTHS 78
Score = 37.1 bits (82), Expect = 0.37
Identities = 23/45 (51%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Frame = +3
Query: 363 MGYAQLEQIGHGIHLRQFSRAFV-IEDNSGDTVKRLVFVSVDAAM 494
MGYA +Q GIH R +SRAF+ E N D VFVS D AM
Sbjct: 1 MGYAHPDQRTAGIHTRLYSRAFITCEINDQDNCN--VFVSADIAM 43
>UniRef50_Q01NW5 Cluster: Putative uncharacterized protein
precursor; n=1; Solibacter usitatus Ellin6076|Rep:
Putative uncharacterized protein precursor - Solibacter
usitatus (strain Ellin6076)
Length = 117
Score = 35.1 bits (77), Expect = 1.5
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Frame = +3
Query: 195 IHNCFLKF-----WINNKNKASKRSIMLYAWCVLACVTAADALRVGAGIADVTGPPA 350
+H F+KF +I+ K K K + AW + AC+TA L + AG A TG A
Sbjct: 51 VHTFFMKFPIDLVYIDKKRKVRKVRNAVPAWRLSACLTAHSILELPAGTAKKTGTQA 107
>UniRef50_Q0DIN1 Cluster: Os05g0375600 protein; n=4; Oryza
sativa|Rep: Os05g0375600 protein - Oryza sativa subsp.
japonica (Rice)
Length = 373
Score = 33.9 bits (74), Expect = 3.4
Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 1/124 (0%)
Frame = -1
Query: 423 PLRTDAGEFHARSARVEHIP*KQFQPVGQ*RQLCQPRHAAHPPPSRTQARTTRITLYFSS 244
P +AG + A SARV+ IP +PV L + P PS + R R +
Sbjct: 213 PSVDNAGTYEATSARVDIIPLFLDRPVN--LHLDENDLEISPSPSDHKRRDHRNSAIRVQ 270
Query: 243 KLCSCYLSKTS-ENNYVCNNVPLISHFTAKTTFTNRQRKQQH*KTTSPTVLPGFTIRTIR 67
+ + +++S E +Y N + IS AK +R+ + + KT + R R
Sbjct: 271 HIRTGVTAESSGERSYFANKMKAISRLKAKLLVISRELRSSNLKTIKRQTVEELYSRETR 330
Query: 66 NTKF 55
KF
Sbjct: 331 RYKF 334
>UniRef50_Q4WS57 Cluster: Leucine carboxyl methyltransferase 1; n=7;
Pezizomycotina|Rep: Leucine carboxyl methyltransferase 1
- Aspergillus fumigatus (Sartorya fumigata)
Length = 398
Score = 33.9 bits (74), Expect = 3.4
Identities = 21/63 (33%), Positives = 29/63 (46%)
Frame = -3
Query: 634 SKRKSIRNPPGSGVSVGAADDHIILVVDYAKALLQPSYYLFPTPCPIIAASTDTKTSRLT 455
+K K IR P ++G + + D AL P+Y+L P +AAS TSR
Sbjct: 158 AKIKFIRAAPLLQRTLGLGSAQNVAIPDSGDALHSPTYHLHPVDLRTLAASGSATTSRSP 217
Query: 454 VSP 446
SP
Sbjct: 218 SSP 220
>UniRef50_A6CDU4 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 478
Score = 33.5 bits (73), Expect = 4.5
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = +3
Query: 303 ALRVGAGIADVTGPPAEIAFMGYAQLEQIGHGIHLRQFSRAFVIEDNS 446
+LR GA D+T PP + G G+H R FSRA V++D +
Sbjct: 31 SLRAGAAAVDITPPPGT-SLDGVISKNGSVTGVHDRIFSRALVLDDGN 77
>UniRef50_Q5DQI8 Cluster: EitB; n=28; Proteobacteria|Rep: EitB -
Escherichia coli
Length = 345
Score = 33.1 bits (72), Expect = 6.0
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +3
Query: 243 SKRSIMLYAWCVLACVTAADALRVGAGIADVTGP 344
+ RSI+L WCVLA + A + VG + ++ P
Sbjct: 8 TSRSILLTGWCVLAAIVLALVIAVGVSVGELAIP 41
>UniRef50_A6SE22 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 734
Score = 33.1 bits (72), Expect = 6.0
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = -1
Query: 318 PRHAAHPPPSRTQARTTRITLYFSSKLCSCYLSKTSENNYV 196
P H A+P S T+ RT+ I +Y S K S Y S ++ V
Sbjct: 590 PIHLANPETSITEVRTSEIVIYSSGKPVSTYYSTLTDTTSV 630
>UniRef50_Q24FA2 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1909
Score = 32.7 bits (71), Expect = 7.9
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Frame = -1
Query: 264 ITLYFSSKLCSCYLSKTSE-NNYVCNNVPLISHFTAKTTFTNRQRKQQH*KTTSPTVLPG 88
+ L FSS+L C L+K+ + + ++ + T+ Q KQ + PTV+ G
Sbjct: 1621 LQLVFSSELSQCKLTKSLILKSNLQQSIKSLEVLHLNITYEQVQDKQFYFLQIGPTVIQG 1680
Query: 87 FTIRTIRNTKFNS 49
FT TI N +S
Sbjct: 1681 FTNVTISNMNIDS 1693
>UniRef50_Q6C3C4 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 436
Score = 32.7 bits (71), Expect = 7.9
Identities = 16/62 (25%), Positives = 28/62 (45%)
Frame = -1
Query: 417 RTDAGEFHARSARVEHIP*KQFQPVGQ*RQLCQPRHAAHPPPSRTQARTTRITLYFSSKL 238
R++ +H+R++ P Q QP P + PPP Q RT+++++
Sbjct: 141 RSEHKNYHSRTSPKRQSPSPQVQPAASATVSSVPPFSMEPPPFTMQRRTSQLSISIPLAT 200
Query: 237 CS 232
CS
Sbjct: 201 CS 202
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 681,906,768
Number of Sequences: 1657284
Number of extensions: 13976054
Number of successful extensions: 42595
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 40898
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42569
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49173558301
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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