Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--1022
(571 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X01179-1|CAA25619.1| 2351|Homo sapiens protein ( Human mRNA for ... 37 0.057
M88648-1|AAA52420.1| 2351|Homo sapiens coagulation factor VIII p... 37 0.057
M14113-1|AAA52485.1| 2351|Homo sapiens F8C protein. 37 0.057
K01740-1|AAA52484.1| 2351|Homo sapiens F8C protein. 37 0.057
BX890586-1|CAI43241.1| 2351|Homo sapiens coagulation factor VIII... 37 0.057
BX842564-3|CAI41666.1| 2351|Homo sapiens coagulation factor VIII... 37 0.057
BX842559-7|CAI41672.1| 2351|Homo sapiens coagulation factor VIII... 37 0.057
BX470111-13|CAI41660.1| 2351|Homo sapiens coagulation factor VII... 37 0.057
AY769950-1|AAV85964.1| 2351|Homo sapiens coagulation factor VIII... 37 0.057
AF441482-1|AAM22406.1| 1105|Homo sapiens alternate SOS1 protein. 37 0.057
L13857-1|AAA35913.1| 1333|Homo sapiens guanine nucleotide exchan... 32 1.6
AC019171-1|AAX93186.1| 1304|Homo sapiens unknown protein. 32 1.6
AB209140-1|BAD92377.1| 988|Homo sapiens son of sevenless homolo... 32 1.6
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 31 2.9
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 31 2.9
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 31 2.9
AL445197-2|CAI15940.1| 148|Homo sapiens discoidin domain recept... 31 2.9
AL445197-1|CAI15939.1| 130|Homo sapiens discoidin domain recept... 31 2.9
BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein. 30 5.0
AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiqui... 30 5.0
AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiqui... 30 5.0
AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiqui... 30 5.0
AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiqui... 30 5.0
AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligas... 30 5.0
AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting ... 30 5.0
AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligas... 30 5.0
Z94056-1|CAI42776.1| 224|Homo sapiens retinoschisis (X-linked, ... 30 6.6
Z92542-1|CAI42483.1| 224|Homo sapiens retinoschisis (X-linked, ... 30 6.6
AF018963-1|AAC18405.1| 224|Homo sapiens X-linked juvenile retin... 30 6.6
AF014459-1|AAC17928.1| 224|Homo sapiens X-linked juvenile retin... 30 6.6
>X01179-1|CAA25619.1| 2351|Homo sapiens protein ( Human mRNA for
factor VIII. ).
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>M88648-1|AAA52420.1| 2351|Homo sapiens coagulation factor VIII
protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>M14113-1|AAA52485.1| 2351|Homo sapiens F8C protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>K01740-1|AAA52484.1| 2351|Homo sapiens F8C protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>BX890586-1|CAI43241.1| 2351|Homo sapiens coagulation factor VIII,
procoagulant component (hemophilia A) protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>BX842564-3|CAI41666.1| 2351|Homo sapiens coagulation factor VIII,
procoagulant component (hemophilia A) protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>BX842559-7|CAI41672.1| 2351|Homo sapiens coagulation factor VIII,
procoagulant component (hemophilia A) protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>BX470111-13|CAI41660.1| 2351|Homo sapiens coagulation factor VIII,
procoagulant component (hemophilia A) protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>AY769950-1|AAV85964.1| 2351|Homo sapiens coagulation factor VIII,
procoagulant component (hemophilia A) protein.
Length = 2351
Score = 36.7 bits (81), Expect = 0.057
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSERPNYEAKNIRLN---SVTGWCGKQEAFTYVSVDLV 259
PLG+ASG I D I A+ + + K RL+ S+ W K E F+++ VDL+
Sbjct: 2043 PLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTK-EPFSWIKVDLL 2095
>AF441482-1|AAM22406.1| 1105|Homo sapiens alternate SOS1 protein.
Length = 1105
Score = 36.7 bits (81), Expect = 0.057
Identities = 23/60 (38%), Positives = 29/60 (48%)
Frame = +2
Query: 38 PGYILINPRPITCMREPECKVIKPLGLASGRIPDSAINATSERPNYEAKNIRLNSVTGWC 217
PG NPRP T MR P +P ++ RIP+S +T+ PN KN S WC
Sbjct: 1038 PGVRPSNPRPGT-MRHPTPLQQEPRKISYSRIPESETESTASAPN-SPKNTVNTSACFWC 1095
>L13857-1|AAA35913.1| 1333|Homo sapiens guanine nucleotide exchange
factor protein.
Length = 1333
Score = 31.9 bits (69), Expect = 1.6
Identities = 18/45 (40%), Positives = 24/45 (53%)
Frame = +2
Query: 38 PGYILINPRPITCMREPECKVIKPLGLASGRIPDSAINATSERPN 172
PG NPRP T MR P +P ++ RIP+S +T+ PN
Sbjct: 1038 PGVRPSNPRPGT-MRHPTPLQQEPRKISYSRIPESETESTASAPN 1081
>AC019171-1|AAX93186.1| 1304|Homo sapiens unknown protein.
Length = 1304
Score = 31.9 bits (69), Expect = 1.6
Identities = 18/45 (40%), Positives = 24/45 (53%)
Frame = +2
Query: 38 PGYILINPRPITCMREPECKVIKPLGLASGRIPDSAINATSERPN 172
PG NPRP T MR P +P ++ RIP+S +T+ PN
Sbjct: 1009 PGVRPSNPRPGT-MRHPTPLQQEPRKISYSRIPESETESTASAPN 1052
>AB209140-1|BAD92377.1| 988|Homo sapiens son of sevenless homolog 1
variant protein.
Length = 988
Score = 31.9 bits (69), Expect = 1.6
Identities = 18/45 (40%), Positives = 24/45 (53%)
Frame = +2
Query: 38 PGYILINPRPITCMREPECKVIKPLGLASGRIPDSAINATSERPN 172
PG NPRP T MR P +P ++ RIP+S +T+ PN
Sbjct: 708 PGVRPSNPRPGT-MRHPTPLQQEPRKISYSRIPESETESTASAPN 751
>X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase
protein.
Length = 855
Score = 31.1 bits (67), Expect = 2.9
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSE-RPNYEAKNIRLNSVTG---WC 217
PLG++ G+IPD I A+S+ + AK RL+S G WC
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWC 73
>BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain receptor
family, member 2 protein.
Length = 855
Score = 31.1 bits (67), Expect = 2.9
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSE-RPNYEAKNIRLNSVTG---WC 217
PLG++ G+IPD I A+S+ + AK RL+S G WC
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWC 73
>AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain receptor
family, member 2 protein.
Length = 855
Score = 31.1 bits (67), Expect = 2.9
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSE-RPNYEAKNIRLNSVTG---WC 217
PLG++ G+IPD I A+S+ + AK RL+S G WC
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWC 73
>AL445197-2|CAI15940.1| 148|Homo sapiens discoidin domain receptor
family, member 2 protein.
Length = 148
Score = 31.1 bits (67), Expect = 2.9
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSE-RPNYEAKNIRLNSVTG---WC 217
PLG++ G+IPD I A+S+ + AK RL+S G WC
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWC 73
>AL445197-1|CAI15939.1| 130|Homo sapiens discoidin domain receptor
family, member 2 protein.
Length = 130
Score = 31.1 bits (67), Expect = 2.9
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +2
Query: 107 PLGLASGRIPDSAINATSE-RPNYEAKNIRLNSVTG---WC 217
PLG++ G+IPD I A+S+ + AK RL+S G WC
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWC 73
>BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein.
Length = 903
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 444 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 499
>AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 444 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 499
>AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 403 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 458
>AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 444 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 499
>AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 403 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 458
>AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligase
ITCH protein.
Length = 862
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 403 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 458
>AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting
protein 4 protein.
Length = 739
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 280 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 335
>AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligase
Itch protein.
Length = 862
Score = 30.3 bits (65), Expect = 5.0
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 343 YKQAENENYVVYFPNFNLTM---RDPGNYGELAMITLPKFVQARFVILGIVSFMDN 501
+++ + N VYF N N + DP + G+L LP+ + RF + GI F+D+
Sbjct: 403 WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDH 458
>Z94056-1|CAI42776.1| 224|Homo sapiens retinoschisis (X-linked,
juvenile) 1 protein.
Length = 224
Score = 29.9 bits (64), Expect = 6.6
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Frame = +2
Query: 86 PECKVIKPLGLASGRI-PDSAINATSER-----PNYEAKNIRLNSV---TGWCGK-QEAF 235
PEC KPLG SG + PD + E+ ++ A RLNS W K Q++
Sbjct: 61 PECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSS 120
Query: 236 TYVSVDL 256
++ +DL
Sbjct: 121 QWLQIDL 127
>Z92542-1|CAI42483.1| 224|Homo sapiens retinoschisis (X-linked,
juvenile) 1 protein.
Length = 224
Score = 29.9 bits (64), Expect = 6.6
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Frame = +2
Query: 86 PECKVIKPLGLASGRI-PDSAINATSER-----PNYEAKNIRLNSV---TGWCGK-QEAF 235
PEC KPLG SG + PD + E+ ++ A RLNS W K Q++
Sbjct: 61 PECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSS 120
Query: 236 TYVSVDL 256
++ +DL
Sbjct: 121 QWLQIDL 127
>AF018963-1|AAC18405.1| 224|Homo sapiens X-linked juvenile
retinoschisis protein protein.
Length = 224
Score = 29.9 bits (64), Expect = 6.6
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Frame = +2
Query: 86 PECKVIKPLGLASGRI-PDSAINATSER-----PNYEAKNIRLNSV---TGWCGK-QEAF 235
PEC KPLG SG + PD + E+ ++ A RLNS W K Q++
Sbjct: 61 PECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSS 120
Query: 236 TYVSVDL 256
++ +DL
Sbjct: 121 QWLQIDL 127
>AF014459-1|AAC17928.1| 224|Homo sapiens X-linked juvenile
retinoschisis precursor protein protein.
Length = 224
Score = 29.9 bits (64), Expect = 6.6
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 10/67 (14%)
Frame = +2
Query: 86 PECKVIKPLGLASGRI-PDSAINATSER-----PNYEAKNIRLNSV---TGWCGK-QEAF 235
PEC KPLG SG + PD + E+ ++ A RLNS W K Q++
Sbjct: 61 PECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSS 120
Query: 236 TYVSVDL 256
++ +DL
Sbjct: 121 QWLQIDL 127
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 86,214,034
Number of Sequences: 237096
Number of extensions: 1857949
Number of successful extensions: 4208
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 4074
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4208
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5816287018
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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