Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--0970
(596 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9V6D6 Cluster: Probable cytochrome P450 301a1, mitocho... 122 8e-27
UniRef50_UPI00015B5FEA Cluster: PREDICTED: similar to cytochrome... 90 4e-17
UniRef50_Q9V5L3 Cluster: Probable cytochrome P450 49a1; n=7; End... 85 9e-16
UniRef50_UPI0000D55ECD Cluster: PREDICTED: similar to Probable c... 77 4e-13
UniRef50_UPI0000584907 Cluster: PREDICTED: similar to cytochrome... 64 2e-09
UniRef50_Q86QN2 Cluster: Cytochrome P450 CYP12F1; n=15; Culicida... 60 3e-08
UniRef50_UPI0000D55C59 Cluster: PREDICTED: similar to Probable c... 54 3e-06
UniRef50_Q9VVR9 Cluster: Probable cytochrome P450 12c1, mitochon... 53 4e-06
UniRef50_O18635 Cluster: Cytochrome P450 CYP12A2; n=6; Schizopho... 53 6e-06
UniRef50_P48416 Cluster: Cytochrome P450 10; n=1; Lymnaea stagna... 48 1e-04
UniRef50_Q7SXE6 Cluster: LOC402831 protein; n=17; Euteleostomi|R... 46 5e-04
UniRef50_A7S334 Cluster: Predicted protein; n=3; Nematostella ve... 45 0.001
UniRef50_UPI0000E46596 Cluster: PREDICTED: similar to cytochrome... 44 0.002
UniRef50_Q6DE36 Cluster: Cyp27a1-prov protein; n=5; Tetrapoda|Re... 44 0.004
UniRef50_P82712 Cluster: Probable cytochrome P450 12d1 proximal,... 44 0.004
UniRef50_A5A7R4 Cluster: Cytochrome P450 side chain cleavage enz... 42 0.015
UniRef50_Q09660 Cluster: Probable cytochrome P450 CYP44; n=2; Ca... 42 0.015
UniRef50_A7T0U5 Cluster: Predicted protein; n=2; Nematostella ve... 41 0.025
UniRef50_UPI0000D9D633 Cluster: PREDICTED: similar to cytochrome... 40 0.034
UniRef50_Q4G0S4 Cluster: Cytochrome P450 27C1; n=21; Euteleostom... 40 0.034
UniRef50_UPI00003C05B8 Cluster: PREDICTED: similar to Probable c... 40 0.044
UniRef50_Q4RIM7 Cluster: Chromosome 11 SCAF15043, whole genome s... 39 0.078
UniRef50_Q9VGZ0 Cluster: Probable cytochrome P450 12e1, mitochon... 39 0.10
UniRef50_O44220 Cluster: Cytochrome P450 12b1, mitochondrial pre... 38 0.14
UniRef50_O15528 Cluster: 25-hydroxyvitamin D-1 alpha hydroxylase... 36 0.96
UniRef50_Q0RJZ3 Cluster: Putative HTH-type transcriptional regul... 35 1.7
UniRef50_A0D0A5 Cluster: Chromosome undetermined scaffold_33, wh... 35 1.7
UniRef50_A2SL96 Cluster: Putative cytochrome; n=1; Methylibium p... 34 2.9
UniRef50_UPI00015B63A0 Cluster: PREDICTED: similar to ENSANGP000... 33 3.9
UniRef50_Q3LFR2 Cluster: Ecdysone 20-hydroxylase; n=2; Obtectome... 33 3.9
UniRef50_Q4RPN7 Cluster: Chromosome 12 SCAF15007, whole genome s... 33 5.1
UniRef50_A5NQ46 Cluster: Phage integrase family protein; n=1; Me... 33 6.7
UniRef50_Q10KH7 Cluster: Putative uncharacterized protein; n=1; ... 33 6.7
UniRef50_Q876Z5 Cluster: Putative SSK22 like MAPKK kinase; n=4; ... 33 6.7
UniRef50_A2EWM0 Cluster: Putative uncharacterized protein; n=2; ... 32 8.9
UniRef50_A0A8M4 Cluster: Cytochrome P450 314 family; n=1; Daphni... 32 8.9
>UniRef50_Q9V6D6 Cluster: Probable cytochrome P450 301a1,
mitochondrial precursor; n=9; Endopterygota|Rep:
Probable cytochrome P450 301a1, mitochondrial precursor
- Drosophila melanogaster (Fruit fly)
Length = 553
Score = 122 bits (293), Expect = 8e-27
Identities = 58/93 (62%), Positives = 72/93 (77%), Gaps = 1/93 (1%)
Frame = +3
Query: 255 DAAKFALRNVAVLELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKVT- 431
DAAK+ALRNVA LELKAPYWRY PTPLW++YV NMNFFV +C +YI A ERLKT+ +
Sbjct: 270 DAAKYALRNVATLELKAPYWRYFPTPLWTRYVKNMNFFVGVCMKYIQSATERLKTQDPSL 329
Query: 432 SENDLSLLERVLRSEGDPKIATIMALT*SLLGL 530
+ SL+E+V+ S+ D KIATIMAL L+G+
Sbjct: 330 RAGEPSLVEKVILSQKDEKIATIMALDLILVGI 362
Score = 118 bits (284), Expect = 1e-25
Identities = 49/85 (57%), Positives = 68/85 (80%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIG 180
FRS+VQ+P+LQ T+++Y+ P+E++TEDF+ + DEN +LP +FDN+IH+WSLECIG
Sbjct: 185 FRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLDENQELPEDFDNEIHKWSLECIG 244
Query: 181 RVALDVRLGCLSPQLNSNSEPQRIM 255
RVALD RLGCL L +SEPQ+I+
Sbjct: 245 RVALDTRLGCLESNLKPDSEPQQII 269
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/30 (80%), Positives = 28/30 (93%), Gaps = 1/30 (3%)
Frame = +2
Query: 506 VDLILVGIDTISMAVCSILYQAATR-LEQQ 592
+DLILVGIDTISMAVCS+LYQ ATR ++QQ
Sbjct: 355 LDLILVGIDTISMAVCSMLYQLATRPVDQQ 384
>UniRef50_UPI00015B5FEA Cluster: PREDICTED: similar to cytochrome
P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
to cytochrome P450 - Nasonia vitripennis
Length = 528
Score = 89.8 bits (213), Expect = 4e-17
Identities = 44/96 (45%), Positives = 64/96 (66%), Gaps = 1/96 (1%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDE-NGDLPHEFDNDIHRWSLECI 177
FRS+V +P++QP+TV+ +VA I+ V DFI M RD DLP F+N++++WSLE I
Sbjct: 159 FRSRVNQPMMQPRTVRHHVAQIDQVAGDFIAKMRQLRDPLTNDLPASFNNELNKWSLESI 218
Query: 178 GRVALDVRLGCLSPQLNSNSEPQRIMMPQSLLYETL 285
+ALD R GCL L ++SEPQR++ ++E L
Sbjct: 219 CLIALDHRFGCLEANLAADSEPQRMINAVHEMFELL 254
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/72 (34%), Positives = 39/72 (54%)
Frame = +3
Query: 291 LELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKVTSENDLSLLERVLR 470
LEL+ W+Y T ++ M+ EI +++I ALER K+K + + S+LER+L
Sbjct: 257 LELQPSLWKYYNTGKLKRFFRAMDTLTEIGNKHIANALERAKSKPDSDNQERSMLERLLA 316
Query: 471 SEGDPKIATIMA 506
D + A MA
Sbjct: 317 I--DERTARTMA 326
>UniRef50_Q9V5L3 Cluster: Probable cytochrome P450 49a1; n=7;
Endopterygota|Rep: Probable cytochrome P450 49a1 -
Drosophila melanogaster (Fruit fly)
Length = 589
Score = 85.4 bits (202), Expect = 9e-16
Identities = 38/85 (44%), Positives = 59/85 (69%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIG 180
FR +VQ +LQPQT KKY+ P+ + +F+ + RDE +LP F +++++W+LE +G
Sbjct: 213 FRQEVQHILLQPQTAKKYIPPLNDIASEFMGRIELMRDEKDELPANFLHELYKWALESVG 272
Query: 181 RVALDVRLGCLSPQLNSNSEPQRIM 255
RV+LD RLGCLSP+ + E Q+I+
Sbjct: 273 RVSLDTRLGCLSPE--GSEEAQQII 295
Score = 58.0 bits (134), Expect = 2e-07
Identities = 29/87 (33%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Frame = +3
Query: 282 VAVLELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKV----TSENDLS 449
V LEL+ P WR PT + +V ++ F IC + I + +++ + SE D+S
Sbjct: 305 VPELELRMPLWRIYPTKAYRSFVKALDQFTAICMKNIGKTMDKADADEARGLSKSEADIS 364
Query: 450 LLERVLRSEGDPKIATIMALT*SLLGL 530
++ER++R G+ K+A I+AL L+G+
Sbjct: 365 IVERIVRKTGNRKLAAILALDLFLVGV 391
Score = 32.3 bits (70), Expect = 8.9
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +2
Query: 506 VDLILVGIDTISMAVCSILYQAATRLEQQ 592
+DL LVG+DT S+A S +YQ A ++Q
Sbjct: 384 LDLFLVGVDTTSVAASSTIYQLAKNPDKQ 412
>UniRef50_UPI0000D55ECD Cluster: PREDICTED: similar to Probable
cytochrome P450 49a1 (CYPXLIXA1); n=3;
Endopterygota|Rep: PREDICTED: similar to Probable
cytochrome P450 49a1 (CYPXLIXA1) - Tribolium castaneum
Length = 513
Score = 76.6 bits (180), Expect = 4e-13
Identities = 30/80 (37%), Positives = 55/80 (68%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIG 180
FR+KV + +LQP+ + YV IE +++ + + +++ ++P +F N++H+WSLE I
Sbjct: 152 FRTKVNQIMLQPRVTRMYVKSIETTSQELVDRIEVIKNKKSEVPDDFLNELHKWSLESIA 211
Query: 181 RVALDVRLGCLSPQLNSNSE 240
++ALDVRLGCL P + +++
Sbjct: 212 KIALDVRLGCLDPNAHPDTQ 231
Score = 58.0 bits (134), Expect = 2e-07
Identities = 33/97 (34%), Positives = 56/97 (57%)
Frame = +3
Query: 240 TATHHDAAKFALRNVAVLELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKT 419
T T +A NV +LELK P+W+ TP + +Y++ ++ EI ++++ AL +L
Sbjct: 230 TQTLINAINTFFMNVPILELKIPFWKIWNTPTFKEYLHALDTIREITLKHVDIALHKLSQ 289
Query: 420 KKVTSENDLSLLERVLRSEGDPKIATIMALT*SLLGL 530
+LS+L+RVL+ E D K A+ +AL L+G+
Sbjct: 290 DDC---EELSVLQRVLKMENDAKTASNLALDMFLVGV 323
Score = 38.3 bits (85), Expect = 0.14
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +2
Query: 422 ESDVRERSLAARTGSEERRRSKDSHHNGVDLILVGIDTISMAVCSILYQAATRLEQQ 592
+ D E S+ R E +K + + +D+ LVG+DT S AV SILYQ + E+Q
Sbjct: 289 QDDCEELSVLQRVLKMEND-AKTASNLALDMFLVGVDTTSNAVASILYQLSLHQEKQ 344
>UniRef50_UPI0000584907 Cluster: PREDICTED: similar to cytochrome
P450; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to cytochrome P450 - Strongylocentrotus
purpuratus
Length = 516
Score = 64.1 bits (149), Expect = 2e-09
Identities = 30/96 (31%), Positives = 60/96 (62%), Gaps = 1/96 (1%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARD-ENGDLPHEFDNDIHRWSLECIG 180
R VQ +++PQ+V Y+ +E +DF+ M + +D E+ ++P EF++ + RW+LE +
Sbjct: 147 RKPVQHLLMKPQSVYAYIPIMEECADDFVTLMKETQDIESQEVP-EFNHKMQRWTLESVC 205
Query: 181 RVALDVRLGCLSPQLNSNSEPQRIMMPQSLLYETLQ 288
+ D R+GCL+ L++N E +++ S +++L+
Sbjct: 206 AIVFDTRMGCLNTGLDNNPEALDMIVSVSNFFDSLK 241
Score = 35.9 bits (79), Expect = 0.72
Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Frame = +3
Query: 291 LELKAPYWRY-IPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKVT---SENDLSLLE 458
L P+W++ I T W+K+ ++F + +Y AL+R+K+ T SE++ + LE
Sbjct: 243 LTFSFPFWKFGITTKAWTKFTEAQDYFFGMSKKYATIALDRMKSAVGTSTQSESEGTFLE 302
Query: 459 RVL 467
+L
Sbjct: 303 CLL 305
>UniRef50_Q86QN2 Cluster: Cytochrome P450 CYP12F1; n=15;
Culicidae|Rep: Cytochrome P450 CYP12F1 - Anopheles
gambiae (African malaria mosquito)
Length = 522
Score = 60.5 bits (140), Expect = 3e-08
Identities = 25/79 (31%), Positives = 50/79 (63%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR 183
R+ V ++QP+ ++ YV ++ V +F+ + + RD ++P +F+ ++RW+LE +G
Sbjct: 154 RTIVNPVMMQPKIIRLYVDQVDAVAREFMTIVAELRDAKCEVPADFNQWLNRWALETMGV 213
Query: 184 VALDVRLGCLSPQLNSNSE 240
+ALD RLG L P+ + ++
Sbjct: 214 LALDTRLGVLRPEQTTGAK 232
>UniRef50_UPI0000D55C59 Cluster: PREDICTED: similar to Probable
cytochrome P450 49a1 (CYPXLIXA1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Probable cytochrome
P450 49a1 (CYPXLIXA1) - Tribolium castaneum
Length = 582
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIG 180
FR +++P+ PQ + + I+ FI + + R+ ++P F +I++W LEC+
Sbjct: 219 FRKSIEQPL--PQLIARQYDKIDDACNKFIARIANIRNRQEEVPGTFQKEIYKWCLECMC 276
Query: 181 RVALDVRLGCLSP-QLNSNSEP 243
V LD +LG L P L+S S+P
Sbjct: 277 LVTLDKKLGFLDPCGLSSTSDP 298
Score = 37.1 bits (82), Expect = 0.31
Identities = 13/42 (30%), Positives = 23/42 (54%)
Frame = +3
Query: 312 WRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKVTSE 437
W+++PTP W V N + + S+Y++ +K KK S+
Sbjct: 322 WQFLPTPAWKSLVENCDAIDNVLSKYVHRIQVLIKEKKEASD 363
>UniRef50_Q9VVR9 Cluster: Probable cytochrome P450 12c1,
mitochondrial precursor; n=2; Sophophora|Rep: Probable
cytochrome P450 12c1, mitochondrial precursor -
Drosophila melanogaster (Fruit fly)
Length = 524
Score = 53.2 bits (122), Expect = 4e-06
Identities = 27/75 (36%), Positives = 48/75 (64%), Gaps = 2/75 (2%)
Frame = +3
Query: 291 LELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERL--KTKKVTSENDLSLLERV 464
L ++ +RYIPTP + K+ M+ + CS Y+N+A+ER+ K+ + S + S+LE++
Sbjct: 246 LGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQGDSNDHKSVLEQL 305
Query: 465 LRSEGDPKIATIMAL 509
L+ D K+A +MA+
Sbjct: 306 LQI--DRKLAVVMAM 318
>UniRef50_O18635 Cluster: Cytochrome P450 CYP12A2; n=6;
Schizophora|Rep: Cytochrome P450 CYP12A2 - Musca
domestica (House fly)
Length = 537
Score = 52.8 bits (121), Expect = 6e-06
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARD-ENGDLPHEFDNDIHRWSLECI 177
FRS V ++QP+ V Y + V ++F++ + RD + ++P F+ +I+RW+LE +
Sbjct: 156 FRSAVNPVLMQPKNVHLYFNKMSEVNKEFMERIRKIRDPQTLEVPDNFEEEINRWTLESV 215
Query: 178 GRVALDVRLGCLSPQLNSNSEPQRIMMPQSLLYE 279
VALD +LG ++ + P+R+ + +E
Sbjct: 216 SVVALDKQLGLITKN-RDDPTPKRLFKALTDFFE 248
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/85 (31%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
Frame = +3
Query: 291 LELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERL----KTKKVTS-ENDLSLL 455
LE + W+YI TP + K + +++ +I Y++EA ER+ K + V EN+ S+L
Sbjct: 253 LEFQPSIWKYIKTPTFKKAIRSLDEITDITKMYVDEAFERIEAENKNRNVEKPENEKSVL 312
Query: 456 ERVLRSEGDPKIATIMALT*SLLGL 530
E++++ D +IA +MA+ + G+
Sbjct: 313 EKLVKI--DKQIAMVMAMDMLMAGV 335
>UniRef50_P48416 Cluster: Cytochrome P450 10; n=1; Lymnaea
stagnalis|Rep: Cytochrome P450 10 - Lymnaea stagnalis
(Great pond snail)
Length = 545
Score = 48.4 bits (110), Expect = 1e-04
Identities = 20/73 (27%), Positives = 42/73 (57%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR 183
R+ V + +L+ V + + V++DF+K + RD +G++P + ++ +W++E IG
Sbjct: 183 RTVVSKKMLKLAEVSNFSTQMGEVSDDFVKRLSHVRDSHGEIP-ALERELFKWAMESIGT 241
Query: 184 VALDVRLGCLSPQ 222
+ R+GCL +
Sbjct: 242 FLFEERIGCLGQE 254
>UniRef50_Q7SXE6 Cluster: LOC402831 protein; n=17; Euteleostomi|Rep:
LOC402831 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 531
Score = 46.4 bits (105), Expect = 5e-04
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIK--YMVDARDENGDLPHEFDNDIHRWSLECI 177
R+ + + +L P+ +Y + V DFIK Y + GDL N ++R+SLE I
Sbjct: 161 RAVLNKRMLHPKDSVQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNKLYRFSLEGI 220
Query: 178 GRVALDVRLGCLSPQLNSNSEPQRIMMPQSLLY 276
+ + R+GCL ++ + ++ + Q L Y
Sbjct: 221 SSILFETRIGCLEKEIPAETQHFINSIAQMLTY 253
>UniRef50_A7S334 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 538
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Frame = +1
Query: 1 FRSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENG-DLPHE---FDNDIHRWSL 168
+RS + + IL+P+ V YV + + F++ + + R + G D +E DN++ +WS
Sbjct: 159 YRSVISKRILRPKEVADYVPEFDNIGSKFLERVENIRGKAGTDSEYEVENLDNELFKWSF 218
Query: 169 ECIGRVALDVRLGCLSPQLNSNSE 240
E + + D R G L +N +++
Sbjct: 219 ESVAYMLFDKRFGTLEENVNPDAQ 242
>UniRef50_UPI0000E46596 Cluster: PREDICTED: similar to cytochrome
P450, family 27, subfamily B, polypeptide 1; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
cytochrome P450, family 27, subfamily B, polypeptide 1 -
Strongylocentrotus purpuratus
Length = 457
Score = 44.4 bits (100), Expect = 0.002
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPI-ELVTE--DFIKYMVDARDENGDLPHEFDNDIHRWSLEC 174
R + R I+ P+ V K+ I E+VT+ + ++++ D + E + E N++++WS
Sbjct: 217 RRTIGRKIMPPREVAKFTGVINEIVTDMVERLRFVRDTKGEGDGVVPELQNEMYKWSKGS 276
Query: 175 IGRVALDVRLGCLSPQLNSNSE 240
I ++ L+ R+GC + S+
Sbjct: 277 IFKLLLETRIGCXKEPIPEKSQ 298
Score = 32.7 bits (71), Expect = 6.7
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 419 EESDVRERS-LAARTGSEERRRSKDSHHNGVDLILVGIDTISMAVCSILYQAATRLEQQD 595
EE DV E S + + ++ K+ + N +L+L G+DT S + LY+ + + QD
Sbjct: 360 EEGDVVEDSGILTHLLASQQLSMKEVYSNACELLLAGVDTTSNTLAWALYELSRHPDTQD 419
>UniRef50_Q6DE36 Cluster: Cyp27a1-prov protein; n=5; Tetrapoda|Rep:
Cyp27a1-prov protein - Xenopus laevis (African clawed
frog)
Length = 542
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDF---IKYMVDARDENGDLPHEFDNDIHRWSLEC 174
RS + + +L+P Y I V DF ++YM A +GD+ ++ N ++R++ E
Sbjct: 172 RSVLNKKMLKPSEASSYAGGINEVVTDFMNKLQYMRKA-SPSGDMVNDVANALYRFAFEG 230
Query: 175 IGRVALDVRLGCLSPQ 222
I + + R+GCL Q
Sbjct: 231 ISNILFETRIGCLEKQ 246
>UniRef50_P82712 Cluster: Probable cytochrome P450 12d1 proximal,
mitochondrial precursor; n=3; Sophophora|Rep: Probable
cytochrome P450 12d1 proximal, mitochondrial precursor -
Drosophila melanogaster (Fruit fly)
Length = 521
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/71 (28%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARD-ENGDLPHEFDNDIHRWSLECIG 180
RS + +QP+ ++ Y P+ + +FI+ + + RD + ++P +F ++I R E +G
Sbjct: 152 RSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLG 211
Query: 181 RVALDVRLGCL 213
VA D ++G +
Sbjct: 212 LVAFDRQMGLI 222
>UniRef50_A5A7R4 Cluster: Cytochrome P450 side chain cleavage
enzyme; n=1; Branchiostoma belcheri|Rep: Cytochrome P450
side chain cleavage enzyme - Branchiostoma belcheri
(Amphioxus)
Length = 530
Score = 41.5 bits (93), Expect = 0.015
Identities = 20/70 (28%), Positives = 36/70 (51%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR 183
R Q +L P+ V +V ++ + + F++ M R + + D ++ +WSLE +
Sbjct: 164 RYAAQSKLLNPKNVCCFVPILDDIAQGFVENMRVGRTATLEPSIDMDAELRKWSLESVVS 223
Query: 184 VALDVRLGCL 213
L +RLGCL
Sbjct: 224 ATLGIRLGCL 233
>UniRef50_Q09660 Cluster: Probable cytochrome P450 CYP44; n=2;
Caenorhabditis|Rep: Probable cytochrome P450 CYP44 -
Caenorhabditis elegans
Length = 489
Score = 41.5 bits (93), Expect = 0.015
Identities = 21/70 (30%), Positives = 39/70 (55%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR 183
RS VQ +++PQ+V+ Y+ ++V+ D + ++ D + G + + RWSLE G+
Sbjct: 142 RSSVQHAMMRPQSVQTYLPFSQIVSNDLVCHVADQQKRFGLV--DMQKVAGRWSLESAGQ 199
Query: 184 VALDVRLGCL 213
+ + LG L
Sbjct: 200 ILFEKSLGSL 209
>UniRef50_A7T0U5 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 471
Score = 40.7 bits (91), Expect = 0.025
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGD--LPHEFDNDIHRWSLECI 177
RS + + +L+P+ V Y + V +DFI + + R D +P+ N + +WS+E I
Sbjct: 106 RSVLNKKMLKPKVVHGYAPELSNVVDDFIGRVNELRSTTSDKTVPN-LQNVLFKWSMESI 164
Query: 178 GRVALDVRLGCLSPQLNSNSE 240
G V + + G S + S+
Sbjct: 165 GTVLYEKQFGAFSKSGSEESQ 185
>UniRef50_UPI0000D9D633 Cluster: PREDICTED: similar to cytochrome
P450, family 27, subfamily a, polypeptide 1; n=1; Macaca
mulatta|Rep: PREDICTED: similar to cytochrome P450,
family 27, subfamily a, polypeptide 1 - Macaca mulatta
Length = 811
Score = 40.3 bits (90), Expect = 0.034
Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIK--YMVDARDENGDLPHEFDNDIHRWSLECI 177
RS +++ IL+P+ V Y + V D IK Y++ ++ E+G+ ++ ++S+E +
Sbjct: 441 RSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGV 500
Query: 178 GRVALDVRLGCLS---PQL 225
+ + RLGCL PQL
Sbjct: 501 ATILYESRLGCLENSIPQL 519
>UniRef50_Q4G0S4 Cluster: Cytochrome P450 27C1; n=21;
Euteleostomi|Rep: Cytochrome P450 27C1 - Homo sapiens
(Human)
Length = 372
Score = 40.3 bits (90), Expect = 0.034
Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIK--YMVDARDENGDLPHEFDNDIHRWSLECI 177
RS +++ IL+P+ V Y + V D IK Y++ ++ E+G+ ++ ++S+E +
Sbjct: 2 RSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGV 61
Query: 178 GRVALDVRLGCLS---PQL 225
+ + RLGCL PQL
Sbjct: 62 ATILYESRLGCLENSIPQL 80
>UniRef50_UPI00003C05B8 Cluster: PREDICTED: similar to Probable
cytochrome P450 12a5, mitochondrial precursor
(CYPXIIA5); n=1; Apis mellifera|Rep: PREDICTED: similar
to Probable cytochrome P450 12a5, mitochondrial
precursor (CYPXIIA5) - Apis mellifera
Length = 518
Score = 39.9 bits (89), Expect = 0.044
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +1
Query: 37 QTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGRVALDVRLGCLS 216
Q + I+ + I + R+ ++P F D+ RW++EC + + RLG L
Sbjct: 187 QISSTFFTKIDTCCNELITRICKIRNRQNEVPVSFYEDLIRWAMECFCDLTFNKRLGFLE 246
Query: 217 P-QLNSNSEPQRIM 255
P NS+SE +++
Sbjct: 247 PIGYNSSSEASKLI 260
>UniRef50_Q4RIM7 Cluster: Chromosome 11 SCAF15043, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF15043, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 519
Score = 39.1 bits (87), Expect = 0.078
Identities = 22/79 (27%), Positives = 40/79 (50%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR 183
RS + + +L+P+ V+ Y + V ED I + R G L + ++ +R+ LE +
Sbjct: 122 RSLLGKHMLRPKAVEAYDQTLNSVVEDLIAKLRLRRSSEG-LVTDIASEFYRFGLEGVSS 180
Query: 184 VALDVRLGCLSPQLNSNSE 240
V + R+GCL + +E
Sbjct: 181 VLFESRIGCLDETVPEETE 199
>UniRef50_Q9VGZ0 Cluster: Probable cytochrome P450 12e1,
mitochondrial precursor; n=4; Sophophora|Rep: Probable
cytochrome P450 12e1, mitochondrial precursor -
Drosophila melanogaster (Fruit fly)
Length = 514
Score = 38.7 bits (86), Expect = 0.10
Identities = 22/78 (28%), Positives = 45/78 (57%), Gaps = 5/78 (6%)
Frame = +3
Query: 291 LELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERL-KTKKVTSENDL----SLL 455
L++ +W+Y+P P + K + +++ + C +I AL+R+ + K + N++ SLL
Sbjct: 235 LDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTLNEIGLETSLL 294
Query: 456 ERVLRSEGDPKIATIMAL 509
E++ R D + A I+A+
Sbjct: 295 EKLARF--DRQTAVIIAM 310
>UniRef50_O44220 Cluster: Cytochrome P450 12b1, mitochondrial
precursor; n=5; Drosophila|Rep: Cytochrome P450 12b1,
mitochondrial precursor - Drosophila acanthoptera (Fruit
fly)
Length = 532
Score = 38.3 bits (85), Expect = 0.14
Identities = 21/79 (26%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHE-FDNDIHRWSLECIG 180
R+KV ++ Q V++ + I+ ++ +F+ + RD + ++ F + W+ E I
Sbjct: 164 RNKVNPVQMRVQNVRQNLPQIDQISREFVDKLDTLRDPVTHILNDNFHEQLKMWAFESIS 223
Query: 181 RVALDVRLGCLSPQLNSNS 237
VAL+ R+G LS + + N+
Sbjct: 224 FVALNTRMGLLSDRPDPNA 242
Score = 37.5 bits (83), Expect = 0.24
Identities = 22/79 (27%), Positives = 46/79 (58%)
Frame = +3
Query: 294 ELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKVTSENDLSLLERVLRS 473
+++ W Y TP + K++ + EI + YI+EA++R + +K S N+ +L+++L
Sbjct: 260 DVQPSIWPYYKTPGFKKFLQTYDKITEITTAYIDEAIKRFEIEK-DSGNE-CVLQQLLSL 317
Query: 474 EGDPKIATIMALT*SLLGL 530
+ K+A +MA+ + G+
Sbjct: 318 --NKKVAVVMAMYMLMAGI 334
>UniRef50_O15528 Cluster: 25-hydroxyvitamin D-1 alpha hydroxylase,
mitochondrial precursor (EC 1.14.13.13) (Cytochrome P450
subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1)
(Calcidiol 1-monooxygenase) (25-OHD-1 alpha-
hydroxylase) (25-hydroxyvitamin D(3)
1-alpha-hydroxylase); n=22; Euteleostomi|Rep:
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
precursor (EC 1.14.13.13) (Cytochrome P450 subfamily
XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol
1-monooxygenase) (25-OHD-1 alpha- hydroxylase)
(25-hydroxyvitamin D(3) 1-alpha-hydroxylase) - Homo
sapiens (Human)
Length = 508
Score = 35.5 bits (78), Expect = 0.96
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLP---HEFDNDIHRWSLEC 174
RS + +L+PQ +Y + V D ++ + R P + + +++ LE
Sbjct: 138 RSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVRDVAGEFYKFGLEG 197
Query: 175 IGRVALDVRLGCLSPQLNSNSE 240
I V L RLGCL Q+ ++E
Sbjct: 198 IAAVLLGSRLGCLEAQVPPDTE 219
>UniRef50_Q0RJZ3 Cluster: Putative HTH-type transcriptional
regulator; n=1; Frankia alni ACN14a|Rep: Putative
HTH-type transcriptional regulator - Frankia alni
(strain ACN14a)
Length = 210
Score = 34.7 bits (76), Expect = 1.7
Identities = 23/64 (35%), Positives = 32/64 (50%)
Frame = -3
Query: 252 DALRF*IAIQLWRQTTQPDVQGDAADTFQRPSVNVVVELMRQVPVLVSGVYHVLNEVLRD 73
DA+ I L R T +PD GD A QR V ++ +VP+L + V +L + D
Sbjct: 61 DAISTWIVEYLHRNTREPDRGGDPAQALQRRLVR-FERMVAEVPLLGAYVRRMLLDGQPD 119
Query: 72 QLDW 61
LDW
Sbjct: 120 GLDW 123
>UniRef50_A0D0A5 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_33, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1179
Score = 34.7 bits (76), Expect = 1.7
Identities = 19/53 (35%), Positives = 28/53 (52%)
Frame = +3
Query: 342 KYVNNMNFFVEICSRYINEALERLKTKKVTSENDLSLLERVLRSEGDPKIATI 500
K +NF VE + + + + LK KK+ END S+L + + D KI TI
Sbjct: 976 KLGKQVNFKVEAMTEQVEKEFQSLKDKKLILENDKSMLIQNMGELDDKKIKTI 1028
>UniRef50_A2SL96 Cluster: Putative cytochrome; n=1; Methylibium
petroleiphilum PM1|Rep: Putative cytochrome -
Methylibium petroleiphilum (strain PM1)
Length = 487
Score = 33.9 bits (74), Expect = 2.9
Identities = 16/59 (27%), Positives = 28/59 (47%)
Frame = +3
Query: 291 LELKAPYWRYIPTPLWSKYVNNMNFFVEICSRYINEALERLKTKKVTSENDLSLLERVL 467
+ L PYW Y+ P+ +Y ++ E ++ A +RL+ + E LLE +L
Sbjct: 210 VNLPFPYWHYLRLPIDREYDRHLRRVHEAVRGFVQAARQRLQDEPTRRERPTDLLEAML 268
>UniRef50_UPI00015B63A0 Cluster: PREDICTED: similar to
ENSANGP00000010656; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010656 - Nasonia
vitripennis
Length = 1989
Score = 33.5 bits (73), Expect = 3.9
Identities = 14/50 (28%), Positives = 29/50 (58%)
Frame = +1
Query: 25 ILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLEC 174
+++ T K++ +E + E+ + +D D+NGD+P EF + H+ + C
Sbjct: 353 LMETNTYKRFNTLVETIFENTEEAALDDIDDNGDVPQEFLINDHQLQILC 402
>UniRef50_Q3LFR2 Cluster: Ecdysone 20-hydroxylase; n=2;
Obtectomera|Rep: Ecdysone 20-hydroxylase - Bombyx mori
(Silk moth)
Length = 516
Score = 33.5 bits (73), Expect = 3.9
Identities = 16/70 (22%), Positives = 37/70 (52%)
Frame = +1
Query: 4 RSKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR 183
R + + P T++ ++ + +++DF++ + +R +G + + F+ +R LE +
Sbjct: 164 RRNLTTDLTSPHTMQNFLPQLNTISDDFLELLNTSRQSDGTV-YAFEQLTNRMGLESVCG 222
Query: 184 VALDVRLGCL 213
+ L RLG L
Sbjct: 223 LMLGSRLGFL 232
>UniRef50_Q4RPN7 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
SCAF15007, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 933
Score = 33.1 bits (72), Expect = 5.1
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Frame = -2
Query: 244 AVLNCYSTVATDNPAGRPRRRGRYIPKTI---CECRCRTHEASPRSRLGRLPC 95
+V NC T NPA +P +R R + + I ECR + +S R+ L L C
Sbjct: 396 SVTNCVITTCLSNPALKPNQRARLLERWIDVARECRILKNFSSLRAILSALQC 448
>UniRef50_A5NQ46 Cluster: Phage integrase family protein; n=1;
Methylobacterium sp. 4-46|Rep: Phage integrase family
protein - Methylobacterium sp. 4-46
Length = 490
Score = 32.7 bits (71), Expect = 6.7
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +1
Query: 37 QTVKKYVAP---IELVTEDFIKYMVDARDENGDLPHEFDNDIHRWSLECIGR-VALDVRL 204
QT+ K+++ IE T F M D R + D+P EF N I W IG+ RL
Sbjct: 413 QTINKWLSEALKIEKTTHSFRHAMRD-RLRHADVPEEFQNLIGGWGTRSIGQGYGQGYRL 471
Query: 205 GCLSPQL 225
G L QL
Sbjct: 472 GQLREQL 478
>UniRef50_Q10KH7 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 155
Score = 32.7 bits (71), Expect = 6.7
Identities = 21/61 (34%), Positives = 26/61 (42%)
Frame = -2
Query: 223 TVATDNPAGRPRRRGRYIPKTICECRCRTHEASPRSRLGRLPCT**SPP*PARLVPRTSS 44
T P GR + GR T CRCRT+ P GRL + +PP P P +
Sbjct: 67 TAVAPAPGGRIAQHGRRAATTQTSCRCRTYRLQPLP--GRLSSS-STPPQPGSGPPHGCT 123
Query: 43 P 41
P
Sbjct: 124 P 124
>UniRef50_Q876Z5 Cluster: Putative SSK22 like MAPKK kinase; n=4;
Sordariomycetes|Rep: Putative SSK22 like MAPKK kinase -
Neurospora crassa
Length = 1367
Score = 32.7 bits (71), Expect = 6.7
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +1
Query: 7 SKVQRPILQPQTVKKYVAPIELVTEDFIKYMVDARDENG-DLPHEFDNDIHRWSLECI 177
S Q P++Q Q + ++ ++L + +YM AR E G DLP D D R LE +
Sbjct: 510 SAQQNPMMQDQMISQFQVLLKLAIKIKREYMEIARPEPGWDLPPCIDEDFDRVILEAL 567
>UniRef50_A2EWM0 Cluster: Putative uncharacterized protein; n=2;
Eukaryota|Rep: Putative uncharacterized protein -
Trichomonas vaginalis G3
Length = 466
Score = 32.3 bits (70), Expect = 8.9
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Frame = +3
Query: 264 KFALRNVAVLELKAPYWRYIPTP-LWSKYVNNMNFFVEICSRYINEALERL-KTKKVTSE 437
+F +N+ +K Y T + K++NN + ++ C + I++ ER+ K KK SE
Sbjct: 35 RFVFKNMENFLIKIDQTAYDDTSWICKKFINNYDLTIDFCEKLISQINERINKAKKTLSE 94
>UniRef50_A0A8M4 Cluster: Cytochrome P450 314 family; n=1; Daphnia
magna|Rep: Cytochrome P450 314 family - Daphnia magna
Length = 526
Score = 32.3 bits (70), Expect = 8.9
Identities = 26/108 (24%), Positives = 48/108 (44%)
Frame = +3
Query: 156 QMVFGMYRPRRLGRPAGLSVATVE*QFRTATHHDAAKFALRNVAVLELKAPYWRYIPTPL 335
+++F + RRLG S+ + + AT + F + + + L P+W+Y PT
Sbjct: 223 EVIFAILLGRRLGALNKSSIPPIAERLMFATEN---LFEVSHETMYGL--PWWKYFPTKS 277
Query: 336 WSKYVNNMNFFVEICSRYINEALERLKTKKVTSENDLSLLERVLRSEG 479
+ K N ++ S + EAL + S +L ++L +EG
Sbjct: 278 YRKLAECENIIYDVFSDLVKEALNSDEATGTQS----PVLNQILTAEG 321
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 575,624,762
Number of Sequences: 1657284
Number of extensions: 11000354
Number of successful extensions: 36414
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 35087
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36389
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41902926763
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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