Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--0824
(594 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for ... 54 3e-07
L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein. 54 3e-07
BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin... 54 3e-07
BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin... 54 3e-07
BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin... 54 3e-07
BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin... 54 3e-07
BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin... 54 3e-07
BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin... 54 3e-07
AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein. 54 3e-07
AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein. 54 3e-07
AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein. 54 3e-07
AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein. 54 3e-07
BX641085-1|CAE46040.1| 2422|Homo sapiens hypothetical protein pr... 51 4e-06
AF191633-1|AAF72339.1| 2602|Homo sapiens filamin protein. 51 4e-06
AF043045-1|AAC33845.1| 2602|Homo sapiens actin-binding protein h... 51 4e-06
AF042166-1|AAC39842.1| 2602|Homo sapiens beta-filamin protein. 51 4e-06
AB209889-1|BAD93126.1| 1613|Homo sapiens filamin B, beta (actin ... 51 4e-06
AB191258-1|BAD52434.1| 2591|Homo sapiens filamin B protein. 51 4e-06
AJ012737-1|CAB46442.1| 2692|Homo sapiens filamin, muscle isoform... 48 2e-05
AF252549-1|AAF67190.1| 2725|Homo sapiens gamma-filamin protein. 48 2e-05
AF184126-1|AAF68195.1| 2705|Homo sapiens filamin 2 protein. 48 2e-05
AF146692-1|AAF80245.1| 2691|Homo sapiens filamin 2 protein. 48 2e-05
AF089841-1|AAD12245.1| 2705|Homo sapiens gamma-filamin protein. 48 2e-05
BC067111-1|AAH67111.1| 983|Homo sapiens FLNA protein protein. 48 3e-05
BC014654-1|AAH14654.1| 838|Homo sapiens FLNA protein protein. 48 3e-05
BX664723-4|CAI43200.2| 281|Homo sapiens filamin A, alpha (actin... 46 1e-04
BC109289-1|AAI09290.3| 307|Homo sapiens FLNA protein protein. 46 1e-04
X70084-1|CAA49689.1| 431|Homo sapiens filamin protein. 45 2e-04
AL137574-1|CAB70818.1| 729|Homo sapiens hypothetical protein pr... 45 2e-04
AB208865-1|BAD92102.1| 1342|Homo sapiens gamma filamin variant p... 45 2e-04
AF238609-1|AAF97046.1| 672|Homo sapiens filamen B protein. 45 2e-04
BX664723-5|CAI43201.1| 231|Homo sapiens filamin A, alpha (actin... 44 3e-04
AJ132990-1|CAB51535.1| 180|Homo sapiens ABP-L, gamma filamin pr... 44 4e-04
AF353667-2|AAL68443.1| 92|Homo sapiens filamin B variant 1 pro... 38 0.027
AF353667-1|AAL68442.1| 133|Homo sapiens filamin B protein. 38 0.027
AF353667-4|AAL68440.1| 94|Homo sapiens filamin B variant 2 pro... 37 0.047
AF353667-3|AAL68441.1| 98|Homo sapiens filamin B variant 3 pro... 37 0.047
X70083-1|CAA49688.1| 231|Homo sapiens filamin protein. 36 0.082
BC034943-1|AAH34943.1| 562|Homo sapiens TRIM45 protein protein. 36 0.11
AY669488-1|AAT76864.1| 580|Homo sapiens tripartite motif-contai... 36 0.11
AL391476-4|CAI12735.1| 523|Homo sapiens tripartite motif-contai... 36 0.11
AL391476-3|CAI12733.1| 580|Homo sapiens tripartite motif-contai... 36 0.11
AL391476-2|CAI12734.1| 562|Homo sapiens tripartite motif-contai... 36 0.11
AK222901-1|BAD96621.1| 580|Homo sapiens tripartite motif-contai... 36 0.11
AK023243-1|BAB14484.1| 580|Homo sapiens protein ( Homo sapiens ... 36 0.11
X70082-1|CAA49687.1| 115|Homo sapiens filamin protein. 34 0.44
BC041179-1|AAH41179.1| 177|Homo sapiens Similar to filamin C, g... 33 0.58
BC064361-1|AAH64361.1| 1056|Homo sapiens pleckstrin homology dom... 32 1.3
AJ002220-1|CAB91652.1| 926|Homo sapiens protein ( Homo sapiens ... 32 1.3
AB002354-1|BAA20813.2| 1058|Homo sapiens KIAA0356 protein protein. 32 1.3
AK096804-1|BAC04866.1| 212|Homo sapiens protein ( Homo sapiens ... 31 2.3
DQ232881-1|ABB18374.1| 868|Homo sapiens LIN41 protein. 31 3.1
AY481572-1|AAS49899.1| 2240|Homo sapiens death inducer-obliterat... 31 3.1
AY481571-1|AAS49898.1| 1189|Homo sapiens death inducer-obliterat... 31 3.1
AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein. 31 3.1
AL117379-2|CAM28273.1| 1189|Homo sapiens death inducer-obliterat... 31 3.1
AL117379-1|CAO03650.1| 2240|Homo sapiens death inducer-obliterat... 31 3.1
AL035669-2|CAI95770.2| 1189|Homo sapiens death inducer-obliterat... 31 3.1
AL035669-1|CAI95769.2| 2240|Homo sapiens death inducer-obliterat... 31 3.1
AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marke... 31 3.1
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 31 3.1
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 31 3.1
AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein. 31 3.1
AB002331-1|BAA20791.2| 1223|Homo sapiens KIAA0333 protein. 31 3.1
AC002310-2|AAC31672.1| 1223|Homo sapiens leukocyte function-asso... 30 5.4
Z34282-1|CAA84036.1| 98|Homo sapiens mucin protein. 30 7.1
BC146788-1|AAI46789.1| 1761|Homo sapiens jumonji domain containi... 30 7.1
BC117693-1|AAI17694.1| 1551|Homo sapiens JMJD1B protein protein. 30 7.1
BC001202-1|AAH01202.1| 759|Homo sapiens JMJD1B protein protein. 30 7.1
BC000539-1|AAH00539.2| 1578|Homo sapiens JMJD1B protein protein. 30 7.1
AF338242-1|AAK13499.1| 1761|Homo sapiens nuclear protein 5qNCA p... 30 7.1
AF251039-1|AAF63765.1| 1417|Homo sapiens putative zinc finger pr... 30 7.1
AB029005-1|BAA83034.2| 1787|Homo sapiens KIAA1082 protein protein. 30 7.1
Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein. 29 9.4
X70085-1|CAA49690.1| 71|Homo sapiens filamin protein. 29 9.4
BC033217-1|AAH33217.1| 611|Homo sapiens SARDH protein protein. 29 9.4
AL590710-3|CAI12276.1| 918|Homo sapiens sarcosine dehydrogenase... 29 9.4
AL590710-2|CAI12275.1| 609|Homo sapiens sarcosine dehydrogenase... 29 9.4
AL365494-4|CAI13356.1| 918|Homo sapiens sarcosine dehydrogenase... 29 9.4
AK223402-1|BAD97122.1| 918|Homo sapiens sarcosine dehydrogenase... 29 9.4
AJ298319-1|CAC83676.1| 372|Homo sapiens mucin 5 protein. 29 9.4
AJ223317-1|CAA11257.1| 475|Homo sapiens sarcosine dehydrogenase... 29 9.4
AF162428-1|AAD43585.1| 918|Homo sapiens sarcosine dehydrogenase... 29 9.4
AF140745-1|AAD32214.1| 918|Homo sapiens sarcosine dehydrogenase... 29 9.4
AF129265-1|AAD33412.1| 602|Homo sapiens unknown protein. 29 9.4
AF095735-1|AAD53398.2| 918|Homo sapiens sarcosine dehydrogenase... 29 9.4
AF047190-1|AAD13137.1| 475|Homo sapiens dimethylglycine dehydro... 29 9.4
AB209544-1|BAD92781.1| 321|Homo sapiens PHD finger protein 13 v... 29 9.4
>X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for
actin-binding protein (filamin) (ABP-280). ).
Length = 2647
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1832 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1891
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1892 DAGEGGLSLAIEG 1904
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2196 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2226
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2423
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2446
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2447 PAEFVVNTSNAGAGALSVTIDG 2468
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2011 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2070
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2071 DTRDAGYGGLSLSIEG 2086
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1892 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1950
Query: 365 HVS 373
V+
Sbjct: 1951 RVT 1953
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2101 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2140
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2295 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2329
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2202 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2261
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2262 WTREAGAGGLAIAVEG 2277
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1707 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1736
Score = 33.1 bits (72), Expect = 0.76
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2610 GSRLYSVSYLLKDKGEYTLVVKWGHEHIPGSPY 2642
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2009 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2040
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1827 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1860
Score = 29.5 bits (63), Expect = 9.4
Identities = 9/30 (30%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY +++ P +T+ +++ GD +P SP+
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPY 1632
>L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein.
Length = 2647
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1832 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1891
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1892 DAGEGGLSLAIEG 1904
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2196 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2226
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2423
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2446
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2447 PAEFVVNTSNAGAGALSVTIDG 2468
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2011 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2070
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2071 DTRDAGYGGLSLSIEG 2086
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1892 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1950
Query: 365 HVS 373
V+
Sbjct: 1951 RVT 1953
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2101 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2140
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2295 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2329
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2202 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2261
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2262 WTREAGAGGLAIAVEG 2277
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1707 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1736
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2610 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2642
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2009 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2040
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1827 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1860
Score = 29.5 bits (63), Expect = 9.4
Identities = 9/30 (30%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY +++ P +T+ +++ GD +P SP+
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPY 1632
>BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1832 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1891
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1892 DAGEGGLSLAIEG 1904
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2196 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2226
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2423
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2446
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2447 PAEFVVNTSNAGAGALSVTIDG 2468
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2011 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2070
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2071 DTRDAGYGGLSLSIEG 2086
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1892 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1950
Query: 365 HVS 373
V+
Sbjct: 1951 RVT 1953
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2101 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2140
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2295 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2329
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2202 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2261
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2262 WTREAGAGGLAIAVEG 2277
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1707 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1736
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2610 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2642
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2009 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2040
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1827 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1860
Score = 29.5 bits (63), Expect = 9.4
Identities = 9/30 (30%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY +++ P +T+ +++ GD +P SP+
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPY 1632
>BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1824 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1883
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1884 DAGEGGLSLAIEG 1896
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2188 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2218
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2380 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2415
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2380 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2438
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2439 PAEFVVNTSNAGAGALSVTIDG 2460
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2003 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2062
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2063 DTRDAGYGGLSLSIEG 2078
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1884 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1942
Query: 365 HVS 373
V+
Sbjct: 1943 RVT 1945
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2093 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2132
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2287 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2321
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2194 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2253
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2254 WTREAGAGGLAIAVEG 2269
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1699 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1728
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2602 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2634
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 1659
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 1660 EETVITVDT 1668
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2001 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2032
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1819 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1852
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 1604 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 1663
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 1664 ITVDTKAAGKGKVTCTV 1680
>BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1792 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1851
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1852 DAGEGGLSLAIEG 1864
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2156 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2186
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2348 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2383
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2348 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2406
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2407 PAEFVVNTSNAGAGALSVTIDG 2428
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 1971 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2030
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2031 DTRDAGYGGLSLSIEG 2046
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1852 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1910
Query: 365 HVS 373
V+
Sbjct: 1911 RVT 1913
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 37.1 bits (82), Expect = 0.047
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSG 406
T+ I +T P + + +RF G+HVP SPF V+AP R + +G
Sbjct: 1699 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF--QVTAPERPLVGVNG 1742
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2061 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2100
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2255 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2289
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2162 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2221
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2222 WTREAGAGGLAIAVEG 2237
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2570 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2602
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 1659
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 1660 EETVITVDT 1668
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 1969 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2000
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1787 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1820
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 1604 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 1663
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 1664 ITVDTKAAGKGKVTCTV 1680
>BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1832 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1891
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1892 DAGEGGLSLAIEG 1904
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2196 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2226
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2423
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2388 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2446
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2447 PAEFVVNTSNAGAGALSVTIDG 2468
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2011 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2070
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2071 DTRDAGYGGLSLSIEG 2086
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1892 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1950
Query: 365 HVS 373
V+
Sbjct: 1951 RVT 1953
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2101 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2140
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2295 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2329
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2202 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2261
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2262 WTREAGAGGLAIAVEG 2277
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1707 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1736
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2610 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2642
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2009 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2040
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1827 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1860
Score = 29.5 bits (63), Expect = 9.4
Identities = 9/30 (30%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY +++ P +T+ +++ GD +P SP+
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPY 1632
>BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1824 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1883
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1884 DAGEGGLSLAIEG 1896
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2188 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2218
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2380 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2415
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2380 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2438
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2439 PAEFVVNTSNAGAGALSVTIDG 2460
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2003 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2062
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2063 DTRDAGYGGLSLSIEG 2078
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1884 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1942
Query: 365 HVS 373
V+
Sbjct: 1943 RVT 1945
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2093 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2132
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2287 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2321
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2194 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2253
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2254 WTREAGAGGLAIAVEG 2269
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1699 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1728
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2602 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2634
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 1659
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 1660 EETVITVDT 1668
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2001 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2032
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1819 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1852
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 1604 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 1663
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 1664 ITVDTKAAGKGKVTCTV 1680
>BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1377 TVETRGAGTGGLGLAVEG 1394
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1033 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1092
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1093 KGAGTGGLGLTVEG 1106
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1792 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1851
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1852 DAGEGGLSLAIEG 1864
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2156 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2186
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2348 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2383
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2348 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2406
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2407 PAEFVVNTSNAGAGALSVTIDG 2428
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 834 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 893
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 894 HFTVNAKAAGKGKLDVQFSG 913
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1118 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1176
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1177 EVGQFQVDCSSAGSAEL 1193
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1413 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1472
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1473 VDTSKAGVAPLQVKVQG 1489
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1025 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1084
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1085 PARFTIDT 1092
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 1971 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2030
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2031 DTRDAGYGGLSLSIEG 2046
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 440 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 499
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 500 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 533
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 931 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 990
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 991 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1019
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 727 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 786
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 787 HEPTYFTVD 795
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1852 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1910
Query: 365 HVS 373
V+
Sbjct: 1911 RVT 1913
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1511 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1570
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1571 DAKDAGEGLLAVQI 1584
Score = 37.1 bits (82), Expect = 0.047
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSG 406
T+ I +T P + + +RF G+HVP SPF V+AP R + +G
Sbjct: 1699 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF--QVTAPERPLVGVNG 1742
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2061 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2100
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2255 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2289
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1126 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1185
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1186 SSAGSAELTIEI 1197
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 437 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 496
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 497 VKETADFKV 505
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2162 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2221
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2222 WTREAGAGGLAIAVEG 2237
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1312 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1364
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2570 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2602
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 933 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 992
Query: 180 VETMAAG 200
V++ AG
Sbjct: 993 VKSKGAG 999
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1411 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1470
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1471 FQVDTSKAGVAPLQVKVQGP 1490
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 1603 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 1659
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 1660 EETVITVDT 1668
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 342 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 401
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 402 TYFEIFTAGAGTGEVEVVI 420
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 1969 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2000
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1787 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1820
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 1604 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 1663
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 1664 ITVDTKAAGKGKVTCTV 1680
>AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein.
Length = 2651
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1329 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1388
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1389 TVETRGAGTGGLGLAVEG 1406
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1045 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1104
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1105 KGAGTGGLGLTVEG 1118
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1836 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1895
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1896 DAGEGGLSLAIEG 1908
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2200 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2230
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2392 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2427
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2392 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2450
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2451 PAEFVVNTSNAGAGALSVTIDG 2472
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 846 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 905
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 906 HFTVNAKAAGKGKLDVQFSG 925
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1130 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1188
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1189 EVGQFQVDCSSAGSAEL 1205
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1425 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1484
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1485 VDTSKAGVAPLQVKVQG 1501
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 1037 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1096
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1097 PARFTIDT 1104
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 2015 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2074
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2075 DTRDAGYGGLSLSIEG 2090
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 452 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 511
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 512 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 545
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 943 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 1002
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 1003 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 1031
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 739 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 798
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 799 HEPTYFTVD 807
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1896 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1954
Query: 365 HVS 373
V+
Sbjct: 1955 RVT 1957
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1523 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1582
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1583 DAKDAGEGLLAVQI 1596
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2105 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2144
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2299 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2333
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1138 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1197
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1198 SSAGSAELTIEI 1209
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 449 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 508
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 509 VKETADFKV 517
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2206 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2265
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2266 WTREAGAGGLAIAVEG 2281
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1324 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1376
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1711 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1740
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2614 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2646
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 945 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 1004
Query: 180 VETMAAG 200
V++ AG
Sbjct: 1005 VKSKGAG 1011
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1423 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1482
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1483 FQVDTSKAGVAPLQVKVQGP 1502
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 1615 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 1671
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 1672 EETVITVDT 1680
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 354 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 413
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 414 TYFEIFTAGAGTGEVEVVI 432
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 2013 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2044
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1831 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1864
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 1616 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 1675
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 1676 ITVDTKAAGKGKVTCTV 1692
>AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein.
Length = 1455
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 133 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 192
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 193 TVETRGAGTGGLGLAVEG 210
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 640 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 699
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 700 DAGEGGLSLAIEG 712
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 1004 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 1034
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 1196 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 1231
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 1196 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 1254
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 1255 PAEFVVNTSNAGAGALSVTIDG 1276
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 229 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 288
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 289 VDTSKAGVAPLQVKVQG 305
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 819 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 878
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 879 DTRDAGYGGLSLSIEG 894
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 700 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 758
Query: 365 HVS 373
V+
Sbjct: 759 RVT 761
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 327 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 386
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 387 DAKDAGEGLLAVQI 400
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 909 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 948
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 1103 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 1137
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 1010 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 1069
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 1070 WTREAGAGGLAIAVEG 1085
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 128 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 180
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 515 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 544
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 1418 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 1450
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 227 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 286
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 287 FQVDTSKAGVAPLQVKVQGP 306
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 419 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 475
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 476 EETVITVDT 484
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 817 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 848
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 635 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 668
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 420 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 479
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 480 ITVDTKAAGKGKVTCTV 496
>AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein.
Length = 2620
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1290 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1349
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1350 TVETRGAGTGGLGLAVEG 1367
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1006 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1065
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1066 KGAGTGGLGLTVEG 1079
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1805 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1864
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1865 DAGEGGLSLAIEG 1877
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2169 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2199
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2361 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2396
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2361 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2419
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2420 PAEFVVNTSNAGAGALSVTIDG 2441
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 807 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 866
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 867 HFTVNAKAAGKGKLDVQFSG 886
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1091 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1149
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1150 EVGQFQVDCSSAGSAEL 1166
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1386 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1445
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1446 VDTSKAGVAPLQVKVQG 1462
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 998 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1057
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1058 PARFTIDT 1065
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 1984 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2043
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2044 DTRDAGYGGLSLSIEG 2059
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 413 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 472
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 473 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 506
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 904 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 963
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 964 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 992
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 700 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 759
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 760 HEPTYFTVD 768
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1865 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1923
Query: 365 HVS 373
V+
Sbjct: 1924 RVT 1926
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1484 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1543
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1544 DAKDAGEGLLAVQI 1557
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2074 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2113
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2268 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2302
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1099 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1158
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1159 SSAGSAELTIEI 1170
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 410 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 469
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 470 VKETADFKV 478
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2175 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2234
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2235 WTREAGAGGLAIAVEG 2250
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1285 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1337
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1680 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1709
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2583 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2615
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 906 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 965
Query: 180 VETMAAG 200
V++ AG
Sbjct: 966 VKSKGAG 972
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1384 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1443
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1444 FQVDTSKAGVAPLQVKVQGP 1463
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 315 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 374
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 375 TYFEIFTAGAGTGEVEVVI 393
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 1982 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2013
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1800 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1833
Score = 29.5 bits (63), Expect = 9.4
Identities = 9/30 (30%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY +++ P +T+ +++ GD +P SP+
Sbjct: 1576 TYTVAYVPDVTGRYTILIKYGGDEIPFSPY 1605
>AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein.
Length = 2612
Score = 54.4 bits (125), Expect = 3e-07
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
++ E+ P G H ++V D P+P+SPF + V D S +RV + GT KP F
Sbjct: 1290 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1349
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + V G
Sbjct: 1350 TVETRGAGTGGLGLAVEG 1367
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRVK----DVAHGTVGKPVTFLVET 188
F+PR G + + V D VP+P SPF L+ V +VK + G+ G P F ++T
Sbjct: 1006 FLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDT 1065
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1066 KGAGTGGLGLTVEG 1079
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 1797 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 1856
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 1857 DAGEGGLSLAIEG 1869
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 2161 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 2191
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 2353 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 2388
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 2353 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 2411
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 2412 PAEFVVNTSNAGAGALSVTIDG 2433
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT----VGKPV 170
F ++ PR G + + VL P SP +KV +D S ++ + +GKP
Sbjct: 807 FTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPT 866
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V AAG G L+V +G
Sbjct: 867 HFTVNAKAAGKGKLDVQFSG 886
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV--SAPARVIGAGSGEPPEKVSVG 433
G T ++S+ P +P + + + F H+PGSPF HV A + SG E+ + G
Sbjct: 1091 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKC-SGPGLERATAG 1149
Query: 434 DAYTFSVDSPTSPHVEV 484
+ F VD ++ E+
Sbjct: 1150 EVGQFQVDCSSAGSAEL 1166
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVK----DVAHGTV--GKPVTFL 179
E++P G + LNV +P SPF + V+DV+ A +VK ++ G V P +F
Sbjct: 1386 EYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQ 1445
Query: 180 VETMAAGPGNLEVTVNG 230
V+T AG L+V V G
Sbjct: 1446 VDTSKAGVAPLQVKVQG 1462
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGS-GEPPEKVSVGD 436
GA + F PR+ P+ VE+ ++G VPGSPF AP + + G + S G
Sbjct: 998 GADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGS 1057
Query: 437 AYTFSVDS 460
F++D+
Sbjct: 1058 PARFTIDT 1065
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 1976 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 2035
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2036 DTRDAGYGGLSLSIEG 2051
Score = 40.3 bits (90), Expect = 0.005
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV-SAIRVKDVAHGTVGKPV---- 170
+ +R + P G H ++V VPIP SP+ + V + + V G K V
Sbjct: 413 STYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKE 472
Query: 171 --TFLVETMAAGPGNLEVTVNGGRVPTAAARKEL 266
F V T AG G L+VTV G + +K+L
Sbjct: 473 TADFKVYTKGAGSGELKVTVKGPKGEERVKQKDL 506
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+TY + +TP P V + + GD +P SPF VS + EKV VG
Sbjct: 904 NTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQE 963
Query: 446 FSVDSPTS-----PHVEVLGPARRPVLCK 517
F+V S + +++GP+ V CK
Sbjct: 964 FTVKSKGAGGQGKVASKIVGPSGAAVPCK 992
Score = 38.7 bits (86), Expect = 0.015
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G TY+ S+ PR P HT + + G +P SPF +V A P +V G G +
Sbjct: 700 GNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKA 759
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 760 HEPTYFTVD 768
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 1857 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 1915
Query: 365 HVS 373
V+
Sbjct: 1916 RVT 1918
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGTVG----KPVTFLV 182
+VP G + ++VL +P SPF +KV +D S ++ T G PV F +
Sbjct: 1484 YVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTI 1543
Query: 183 ETMAAGPGNLEVTV 224
+ AG G L V +
Sbjct: 1544 DAKDAGEGLLAVQI 1557
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 2066 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 2105
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 2260 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 2294
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
+VP G++ +N+L IP SPF V +D S ++ + T G+ F V+
Sbjct: 1099 YVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDC 1158
Query: 189 MAAGPGNLEVTV 224
+AG L + +
Sbjct: 1159 SSAGSAELTIEI 1170
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G TY S+ P HTV + F G +P SP+ V P+ G G P+ V
Sbjct: 410 RGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVR 469
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 470 VKETADFKV 478
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 2167 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 2226
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2227 WTREAGAGGLAIAVEG 2242
Score = 34.3 bits (75), Expect = 0.33
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSG 406
+G Y + +TP + H+V++ ++G VP SPF V+ P+RV G G
Sbjct: 1285 RGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPG 1337
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 1672 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 1701
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 2575 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2607
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFL 179
+ ++ P G +NV PIP SPF + V D+S I+V + VGK F
Sbjct: 906 YTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFT 965
Query: 180 VETMAAG 200
V++ AG
Sbjct: 966 VKSKGAG 972
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 275 AISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++ + P + +++ + + G VPGSPF V V+ ++V +G G P V +
Sbjct: 1384 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1443
Query: 446 FSVDSP---TSP-HVEVLGP 493
F VD+ +P V+V GP
Sbjct: 1444 FQVDTSKAGVAPLQVKVQGP 1463
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV-----SAPARVIGAGSGEPPEKVSVG 433
TY +++ P +T+ +++ GD +P SP+ ++ V GAG G + +G
Sbjct: 1576 TYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIG---PTIQIG 1632
Query: 434 DAYTFSVDS 460
+ +VD+
Sbjct: 1633 EETVITVDT 1641
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHG--------TVGKP 167
F +VP G H++ VL I SPF + V K A G K
Sbjct: 315 FSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKT 374
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G +EV +
Sbjct: 375 TYFEIFTAGAGTGEVEVVI 393
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 1974 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 2005
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 1792 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1825
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 6/77 (7%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRVKDVAHG---TVGKPVT 173
+ +VP G + + + IP SP+ ++ D S V G +G+
Sbjct: 1577 YTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETV 1636
Query: 174 FLVETMAAGPGNLEVTV 224
V+T AAG G + TV
Sbjct: 1637 ITVDTKAAGKGKVTCTV 1653
>BX641085-1|CAE46040.1| 2422|Homo sapiens hypothetical protein
protein.
Length = 2422
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRV--KDVAHGTVGKPVTFLV 182
A+F+PR G + ++V D P+P SP+ ++ D S ++ + G VGKP F +
Sbjct: 835 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 894
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +TV G
Sbjct: 895 DTKGAGTGGLGLTVEG 910
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G Y + P P PH V++ F GD +P SPFV V P +G G P+ V
Sbjct: 240 KGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVR 299
Query: 428 VGDAYTFSVDSPTSPHVEVLGPARRPVLCKYLLKK 532
+ + F VD+ + E+ + P + L+K+
Sbjct: 300 IRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQ 334
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK----DVAHGTVGKPV 170
F ++VP A G + + VL S IPASPF +KV +D S ++ + A GKP
Sbjct: 638 FTVKYVPPATGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPT 697
Query: 171 TFLVETMAAGPGNLEVTVN 227
F V T AG L V N
Sbjct: 698 HFTVYTKGAGKAPLNVQFN 716
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 2163 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 2200
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHGT----VGKPVTF 176
++ E+ P G H + V D VPIP SPF + V + RV+ G KP F
Sbjct: 1121 YQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVF 1180
Query: 177 LVETMAAGPGNLEVTVNG 230
V T AG G L +TV G
Sbjct: 1181 TVVTRGAGIGGLGITVEG 1198
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARV 388
+G +CS G T ++S+ P P + V + F H+PGSPF + P++V
Sbjct: 909 EGPCEAKIECSDN-GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 967
Query: 389 IGAGSGEPPEKVSVGDAYTFSVD 457
+ +G G E VG+A SVD
Sbjct: 968 VASGPG--LEHGKVGEAGLLSVD 988
Score = 39.9 bits (89), Expect = 0.007
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L + V IP SPF + +D S + + HG VG+ V+
Sbjct: 930 YLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDC 989
Query: 189 MAAGPGNL 212
AGPG L
Sbjct: 990 SEAGPGAL 997
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 2160 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 2218
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 2219 TGIQSEFFINTTRAGPGTLSVTIEG 2243
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 1969 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 2001
Score = 37.5 bits (83), Expect = 0.035
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV--IGAGSGEPPEKVSVGDAY 442
T +S+ P P + V +F +HVPGSPF +S RV + P +VG
Sbjct: 1876 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESSTRTSRAPSVATVGSIC 1935
Query: 443 TFSVDSP 463
++ P
Sbjct: 1936 DLNLKIP 1942
Score = 37.1 bits (82), Expect = 0.047
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+++ + +TP V + GD +P SPF V+AP + +V VG
Sbjct: 735 YSHTVKYTPTQQGNMQVLVTHGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQE 794
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLC 514
F+VD+ + V +L P+R+ V C
Sbjct: 795 FTVDTRGAGGQGKLDVTILSPSRKVVPC 822
Score = 36.3 bits (80), Expect = 0.082
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 239 TDCSGTQGAH-TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS---APARVIGAGSG 406
T+C T A TY + +TP + H VE+ ++ +P SPF V+ P+RV G G
Sbjct: 1109 TECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPG 1168
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 2070 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 2104
Score = 35.1 bits (77), Expect = 0.19
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFLVET 188
++ P G ++ V PIP SPF + V D+S I++ + + VGK F V+T
Sbjct: 740 KYTPTQQGNMQVLVTHGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDT 799
Query: 189 M-AAGPGNLEVTV 224
A G G L+VT+
Sbjct: 800 RGAGGQGKLDVTI 812
Score = 34.7 bits (76), Expect = 0.25
Identities = 15/67 (22%), Positives = 32/67 (47%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G + +G + C + T +++ P P +++ +++N H+PGSPF
Sbjct: 1668 DAGEGGLDLAIEGPSKAEISCIDNKDG-TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTA 1726
Query: 365 HVSAPAR 385
++ +R
Sbjct: 1727 KITDDSR 1733
Score = 34.3 bits (75), Expect = 0.33
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSVGDA 439
TYA S+TP HT+ + + G ++P SP+ ++ S P +V G G + +
Sbjct: 534 TYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEP 593
Query: 440 YTFSVD 457
F+VD
Sbjct: 594 THFTVD 599
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 1977 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 2036
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2037 WTREAGAGGLSIAVEG 2052
Score = 33.1 bits (72), Expect = 0.76
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G F PR+ + V++ ++G VPGSP+ S P++V G G E V
Sbjct: 829 GRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPG--LEGGLV 886
Query: 431 GDAYTFSVDS 460
G F++D+
Sbjct: 887 GKPAEFTIDT 896
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 1786 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 1845
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 1846 DTRDAGYGGISLAVEG 1861
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ +++TP P+ V +++ + +P SPF V ++V +G G V
Sbjct: 1306 GDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPA 1365
Query: 431 GDAYTFSVDS 460
F++D+
Sbjct: 1366 SLPVDFAIDA 1375
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 1784 ISFIPREVGEHLVSIKKNGNHVANSP 1809
Score = 31.5 bits (68), Expect = 2.3
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKDVAHGTVG----KPV 170
+R + P G H + + IP SPF ++V + +A R G +
Sbjct: 245 YRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETT 304
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V+T AAG G L VT+ G
Sbjct: 305 DFKVDTKAAGSGELGVTMKG 324
Score = 31.5 bits (68), Expect = 2.3
Identities = 12/37 (32%), Positives = 19/37 (51%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
YA + P P +++ + + G H+P SPF V A
Sbjct: 342 YAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEA 378
Score = 31.5 bits (68), Expect = 2.3
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 7/77 (9%)
Frame = +2
Query: 284 FTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
+ P P + V + + G H+PGSP V V P++V AG G V +F+V
Sbjct: 1218 YIPFAPGDYDVNITYGGAHIPGSPLRVPVKDVVDPSKVKIAGPG-LGSGVRARVLQSFTV 1276
Query: 455 DSPTSP----HVEVLGP 493
DS + V VLGP
Sbjct: 1277 DSSKAGLAPLEVRVLGP 1293
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 2385 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 2422
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDA 439
TYA+++ P + + + + GD +P SP+ ++ + G G V G+
Sbjct: 1406 TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPG-IASTVKTGEE 1464
Query: 440 YTFSVDSPTS 469
F VD+ T+
Sbjct: 1465 VGFVVDAKTA 1474
Score = 30.3 bits (65), Expect = 5.4
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY I +T P + + +RF G +P SPF
Sbjct: 1502 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 1531
>AF191633-1|AAF72339.1| 2602|Homo sapiens filamin protein.
Length = 2602
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRV--KDVAHGTVGKPVTFLV 182
A+F+PR G + ++V D P+P SP+ ++ D S ++ + G VGKP F +
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +TV G
Sbjct: 1064 DTKGAGTGGLGLTVEG 1079
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G Y + P P PH V++ F GD +P SPFV V P +G G P+ V
Sbjct: 409 KGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVR 468
Query: 428 VGDAYTFSVDSPTSPHVEVLGPARRPVLCKYLLKK 532
+ + F VD+ + E+ + P + L+K+
Sbjct: 469 IRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQ 503
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK----DVAHGTVGKPV 170
F ++VP A G + + VL S IPASPF +KV +D S ++ + A GKP
Sbjct: 807 FTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPT 866
Query: 171 TFLVETMAAGPGNLEVTVN 227
F V T AG L V N
Sbjct: 867 HFTVYTKGAGKAPLNVQFN 885
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 2343 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 2380
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHGT----VGKPVTF 176
++ E+ P G H + V D VPIP SPF + V + RV+ G KP F
Sbjct: 1290 YQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVF 1349
Query: 177 LVETMAAGPGNLEVTVNG 230
V T AG G L +TV G
Sbjct: 1350 TVVTRGAGIGGLGITVEG 1367
Score = 41.9 bits (94), Expect = 0.002
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARV 388
+G +CS G T ++S+ P P + V + F H+PGSPF + P++V
Sbjct: 1078 EGPCEAKIECSDN-GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 1136
Query: 389 IGAGSGEPPEKVSVGDAYTFSVD 457
+ +G G E VG+A SV+
Sbjct: 1137 VASGPG--LEHGKVGEAGLLSVN 1157
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 2340 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 2398
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 2399 TGIQSEFFINTTRAGPGTLSVTIEG 2423
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHGTVGKPV------TFL 179
AE++P A G++ +N+ IP SPF + V DV +A +G V +F
Sbjct: 1385 AEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFT 1444
Query: 180 VETMAAGPGNLEVTVNGGR 236
V++ AG LEV V G R
Sbjct: 1445 VDSSKAGLAPLEVRVLGPR 1463
Score = 39.1 bits (87), Expect = 0.012
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L + V IP SPF + +D S + + HG VG+ V
Sbjct: 1099 YLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVNC 1158
Query: 189 MAAGPGNL 212
AGPG L
Sbjct: 1159 SEAGPGAL 1166
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+++ + +TP V + + GD +P SPF V+AP + +V VG
Sbjct: 904 YSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQE 963
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLC 514
F+VD+ + V +L P+R+ V C
Sbjct: 964 FTVDTRGAGGQGKLDVTILSPSRKVVPC 991
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 2149 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 2181
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 2056 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 2095
Score = 36.3 bits (80), Expect = 0.082
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 239 TDCSGTQGAH-TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS---APARVIGAGSG 406
T+C T A TY + +TP + H VE+ ++ +P SPF V+ P+RV G G
Sbjct: 1278 TECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPG 1337
Score = 35.9 bits (79), Expect = 0.11
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFLVET 188
++ P G ++ V PIP SPF + V D+S I++ + + VGK F V+T
Sbjct: 909 KYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDT 968
Query: 189 M-AAGPGNLEVTV 224
A G G L+VT+
Sbjct: 969 RGAGGQGKLDVTI 981
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 2250 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 2284
Score = 34.7 bits (76), Expect = 0.25
Identities = 15/67 (22%), Positives = 32/67 (47%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G + +G + C + T +++ P P +++ +++N H+PGSPF
Sbjct: 1848 DAGEGGLDLAIEGPSKAEISCIDNKDG-TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTA 1906
Query: 365 HVSAPAR 385
++ +R
Sbjct: 1907 KITDDSR 1913
Score = 34.3 bits (75), Expect = 0.33
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSVGDA 439
TYA S+TP HT+ + + G ++P SP+ ++ S P +V G G + +
Sbjct: 703 TYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEP 762
Query: 440 YTFSVD 457
F+VD
Sbjct: 763 THFTVD 768
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 2157 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 2216
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2217 WTREAGAGGLSIAVEG 2232
Score = 33.9 bits (74), Expect = 0.44
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Frame = +2
Query: 284 FTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
+ P P + V + + G H+PGSPF V V P++V AG G V +F+V
Sbjct: 1387 YIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPG-LGSGVRARVLQSFTV 1445
Query: 455 DSPTSP----HVEVLGP 493
DS + V VLGP
Sbjct: 1446 DSSKAGLAPLEVRVLGP 1462
Score = 33.1 bits (72), Expect = 0.76
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G F PR+ + V++ ++G VPGSP+ S P++V G G E V
Sbjct: 998 GRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPG--LEGGLV 1055
Query: 431 GDAYTFSVDS 460
G F++D+
Sbjct: 1056 GKPAEFTIDT 1065
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 1966 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 2025
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 2026 DTRDAGYGGISLAVEG 2041
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ +++TP P+ V +++ + +P SPF V ++V +G G V
Sbjct: 1475 GDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPA 1534
Query: 431 GDAYTFSVDS 460
F++D+
Sbjct: 1535 SLPVDFAIDA 1544
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 1964 ISFIPREVGEHLVSIKKNGNHVANSP 1989
Score = 31.5 bits (68), Expect = 2.3
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKDVAHGTVG----KPV 170
+R + P G H + + IP SPF ++V + +A R G +
Sbjct: 414 YRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETT 473
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V+T AAG G L VT+ G
Sbjct: 474 DFKVDTKAAGSGELGVTMKG 493
Score = 31.5 bits (68), Expect = 2.3
Identities = 12/37 (32%), Positives = 19/37 (51%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
YA + P P +++ + + G H+P SPF V A
Sbjct: 511 YAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEA 547
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 2565 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 2602
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDA 439
TYA+++ P + + + + GD +P SP+ ++ + G G V G+
Sbjct: 1575 TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPG-IASTVKTGEE 1633
Query: 440 YTFSVDSPTS 469
F VD+ T+
Sbjct: 1634 VGFVVDAKTA 1643
Score = 30.3 bits (65), Expect = 5.4
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY I +T P + + +RF G +P SPF
Sbjct: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 1700
>AF043045-1|AAC33845.1| 2602|Homo sapiens actin-binding protein
homolog ABP-278 protein.
Length = 2602
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRV--KDVAHGTVGKPVTFLV 182
A+F+PR G + ++V D P+P SP+ ++ D S ++ + G VGKP F +
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +TV G
Sbjct: 1064 DTKGAGTGGLGLTVEG 1079
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G Y + P P PH V++ F GD +P SPFV V P +G G P+ V
Sbjct: 409 KGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVR 468
Query: 428 VGDAYTFSVDSPTSPHVEVLGPARRPVLCKYLLKK 532
+ + F VD+ + E+ + P + L+K+
Sbjct: 469 IRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQ 503
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK----DVAHGTVGKPV 170
F ++VP A G + + VL S IPASPF +KV +D S ++ + A GKP
Sbjct: 807 FTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPT 866
Query: 171 TFLVETMAAGPGNLEVTVN 227
F V T AG L V N
Sbjct: 867 HFTVYTKGAGKAPLNVQFN 885
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 2343 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 2380
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHGT----VGKPVTF 176
++ E+ P G H + V D VPIP SPF + V + RV+ G KP F
Sbjct: 1290 YQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVF 1349
Query: 177 LVETMAAGPGNLEVTVNG 230
V T AG G L +TV G
Sbjct: 1350 TVVTRGAGIGGLGITVEG 1367
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARV 388
+G +CS G T ++S+ P P + V + F H+PGSPF + P++V
Sbjct: 1078 EGPCEAKIECSDN-GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 1136
Query: 389 IGAGSGEPPEKVSVGDAYTFSVD 457
+ +G G E VG+A SVD
Sbjct: 1137 VASGPG--LEHGKVGEAGLLSVD 1157
Score = 39.9 bits (89), Expect = 0.007
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L + V IP SPF + +D S + + HG VG+ V+
Sbjct: 1099 YLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDC 1158
Query: 189 MAAGPGNL 212
AGPG L
Sbjct: 1159 SEAGPGAL 1166
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 2340 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 2398
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 2399 TGIQSEFFINTTRAGPGTLSVTIEG 2423
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHGTVGKPV------TFL 179
AE++P A G++ +N+ IP SPF + V DV +A +G V +F
Sbjct: 1385 AEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFT 1444
Query: 180 VETMAAGPGNLEVTVNGGR 236
V++ AG LEV V G R
Sbjct: 1445 VDSSKAGLAPLEVRVLGPR 1463
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+++ + +TP V + + GD +P SPF V+AP + +V VG
Sbjct: 904 YSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQE 963
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLC 514
F+VD+ + V +L P+R+ V C
Sbjct: 964 FTVDTRGAGGQGKLDVTILSPSRKVVPC 991
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 2149 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 2181
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 2056 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 2095
Score = 36.3 bits (80), Expect = 0.082
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 239 TDCSGTQGAH-TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS---APARVIGAGSG 406
T+C T A TY + +TP + H VE+ ++ +P SPF V+ P+RV G G
Sbjct: 1278 TECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPG 1337
Score = 35.9 bits (79), Expect = 0.11
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFLVET 188
++ P G ++ V PIP SPF + V D+S I++ + + VGK F V+T
Sbjct: 909 KYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDT 968
Query: 189 M-AAGPGNLEVTV 224
A G G L+VT+
Sbjct: 969 RGAGGQGKLDVTI 981
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 2250 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 2284
Score = 34.7 bits (76), Expect = 0.25
Identities = 15/67 (22%), Positives = 32/67 (47%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G + +G + C + T +++ P P +++ +++N H+PGSPF
Sbjct: 1848 DAGEGGLDLAIEGPSKAEISCIDNKDG-TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTA 1906
Query: 365 HVSAPAR 385
++ +R
Sbjct: 1907 KITDDSR 1913
Score = 34.3 bits (75), Expect = 0.33
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSVGDA 439
TYA S+TP HT+ + + G ++P SP+ ++ S P +V G G + +
Sbjct: 703 TYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEP 762
Query: 440 YTFSVD 457
F+VD
Sbjct: 763 THFTVD 768
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 2157 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 2216
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2217 WTREAGAGGLSIAVEG 2232
Score = 33.9 bits (74), Expect = 0.44
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Frame = +2
Query: 284 FTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
+ P P + V + + G H+PGSPF V V P++V AG G V +F+V
Sbjct: 1387 YIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPG-LGSGVRARVLQSFTV 1445
Query: 455 DSPTSP----HVEVLGP 493
DS + V VLGP
Sbjct: 1446 DSSKAGLAPLEVRVLGP 1462
Score = 33.5 bits (73), Expect = 0.58
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D RV + ++ G + F+V
Sbjct: 1966 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRARVYGRGLSEGRTFEMSDFIV 2025
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 2026 DTRDAGYGGISLAVEG 2041
Score = 33.1 bits (72), Expect = 0.76
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G F PR+ + V++ ++G VPGSP+ S P++V G G E V
Sbjct: 998 GRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPG--LEGGLV 1055
Query: 431 GDAYTFSVDS 460
G F++D+
Sbjct: 1056 GKPAEFTIDT 1065
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ +++TP P+ V +++ + +P SPF V ++V +G G V
Sbjct: 1475 GDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPA 1534
Query: 431 GDAYTFSVDS 460
F++D+
Sbjct: 1535 SLPVDFAIDA 1544
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 1964 ISFIPREVGEHLVSIKKNGNHVANSP 1989
Score = 31.5 bits (68), Expect = 2.3
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKDVAHGTVG----KPV 170
+R + P G H + + IP SPF ++V + +A R G +
Sbjct: 414 YRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETT 473
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V+T AAG G L VT+ G
Sbjct: 474 DFKVDTKAAGSGELGVTMKG 493
Score = 31.5 bits (68), Expect = 2.3
Identities = 12/37 (32%), Positives = 19/37 (51%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
YA + P P +++ + + G H+P SPF V A
Sbjct: 511 YAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEA 547
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 2565 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 2602
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDA 439
TYA+++ P + + + + GD +P SP+ ++ + G G V G+
Sbjct: 1575 TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPG-IASTVKTGEE 1633
Query: 440 YTFSVDSPTS 469
F VD+ T+
Sbjct: 1634 VGFVVDAKTA 1643
Score = 30.3 bits (65), Expect = 5.4
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY I +T P + + +RF G +P SPF
Sbjct: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 1700
>AF042166-1|AAC39842.1| 2602|Homo sapiens beta-filamin protein.
Length = 2602
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRV--KDVAHGTVGKPVTFLV 182
A+F+PR G + ++V D P+P SP+ ++ D S ++ + G VGKP F +
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +TV G
Sbjct: 1064 DTKGAGTGGLGLTVEG 1079
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G Y + P P PH V++ F GD +P SPFV V P +G G P+ V
Sbjct: 409 KGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVR 468
Query: 428 VGDAYTFSVDSPTSPHVEVLGPARRPVLCKYLLKK 532
+ + F VD+ + E+ + P + L+K+
Sbjct: 469 IRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQ 503
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK----DVAHGTVGKPV 170
F ++VP A G + + VL S IPASPF +KV +D S ++ + A GKP
Sbjct: 807 FTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPT 866
Query: 171 TFLVETMAAGPGNLEVTVN 227
F V T AG L V N
Sbjct: 867 HFTVYTKGAGKAPLNVQFN 885
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 2343 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 2380
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHGT----VGKPVTF 176
++ E+ P G H + V D VPIP SPF + V + RV+ G KP F
Sbjct: 1290 YQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVF 1349
Query: 177 LVETMAAGPGNLEVTVNG 230
V T AG G L +TV G
Sbjct: 1350 TVVTRGAGIGGLGITVEG 1367
Score = 41.9 bits (94), Expect = 0.002
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARV 388
+G +CS G T ++S+ P P + V + F H+PGSPF + P++V
Sbjct: 1078 EGPCEAKIECSDN-GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 1136
Query: 389 IGAGSGEPPEKVSVGDAYTFSVD 457
+ +G G E VG+A SV+
Sbjct: 1137 VASGPG--LEHGKVGEAGLLSVN 1157
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 2340 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 2398
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 2399 TGIQSEFFINTTRAGPGTLSVTIEG 2423
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHGTVGKPV------TFL 179
AE++P A G++ +N+ IP SPF + V DV +A +G V +F
Sbjct: 1385 AEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFT 1444
Query: 180 VETMAAGPGNLEVTVNGGR 236
V++ AG LEV V G R
Sbjct: 1445 VDSSKAGLAPLEVRVLGPR 1463
Score = 39.1 bits (87), Expect = 0.012
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L + V IP SPF + +D S + + HG VG+ V
Sbjct: 1099 YLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVNC 1158
Query: 189 MAAGPGNL 212
AGPG L
Sbjct: 1159 SEAGPGAL 1166
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+++ + +TP V + + GD +P SPF V+AP + +V VG
Sbjct: 904 YSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQE 963
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLC 514
F+VD+ + V +L P+R+ V C
Sbjct: 964 FTVDTRGAGGQGKLDVTILSPSRKVVPC 991
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 2149 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 2181
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 2056 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 2095
Score = 36.3 bits (80), Expect = 0.082
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 239 TDCSGTQGAH-TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS---APARVIGAGSG 406
T+C T A TY + +TP + H VE+ ++ +P SPF V+ P+RV G G
Sbjct: 1278 TECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPG 1337
Score = 35.9 bits (79), Expect = 0.11
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFLVET 188
++ P G ++ V PIP SPF + V D+S I++ + + VGK F V+T
Sbjct: 909 KYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDT 968
Query: 189 M-AAGPGNLEVTV 224
A G G L+VT+
Sbjct: 969 RGAGGQGKLDVTI 981
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 2250 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 2284
Score = 34.7 bits (76), Expect = 0.25
Identities = 15/67 (22%), Positives = 32/67 (47%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G + +G + C + T +++ P P +++ +++N H+PGSPF
Sbjct: 1848 DAGEGGLDLAIEGPSKAEISCIDNKDG-TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTA 1906
Query: 365 HVSAPAR 385
++ +R
Sbjct: 1907 KITDDSR 1913
Score = 34.3 bits (75), Expect = 0.33
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSVGDA 439
TYA S+TP HT+ + + G ++P SP+ ++ S P +V G G + +
Sbjct: 703 TYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEP 762
Query: 440 YTFSVD 457
F+VD
Sbjct: 763 THFTVD 768
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 2157 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 2216
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2217 WTREAGAGGLSIAVEG 2232
Score = 33.9 bits (74), Expect = 0.44
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Frame = +2
Query: 284 FTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
+ P P + V + + G H+PGSPF V V P++V AG G V +F+V
Sbjct: 1387 YIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPG-LGSGVRARVLQSFTV 1445
Query: 455 DSPTSP----HVEVLGP 493
DS + V VLGP
Sbjct: 1446 DSSKAGLAPLEVRVLGP 1462
Score = 33.1 bits (72), Expect = 0.76
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G F PR+ + V++ ++G VPGSP+ S P++V G G E V
Sbjct: 998 GRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPG--LEGGLV 1055
Query: 431 GDAYTFSVDS 460
G F++D+
Sbjct: 1056 GKPAEFTIDT 1065
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 1966 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 2025
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 2026 DTRDAGYGGISLAVEG 2041
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ +++TP P+ V +++ + +P SPF V ++V +G G V
Sbjct: 1475 GDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPA 1534
Query: 431 GDAYTFSVDS 460
F++D+
Sbjct: 1535 SLPVDFAIDA 1544
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 1964 ISFIPREVGEHLVSIKKNGNHVANSP 1989
Score = 31.5 bits (68), Expect = 2.3
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKDVAHGTVG----KPV 170
+R + P G H + + IP SPF ++V + +A R G +
Sbjct: 414 YRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETT 473
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V+T AAG G L VT+ G
Sbjct: 474 DFKVDTKAAGSGELGVTMKG 493
Score = 31.5 bits (68), Expect = 2.3
Identities = 12/37 (32%), Positives = 19/37 (51%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
YA + P P +++ + + G H+P SPF V A
Sbjct: 511 YAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEA 547
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 2565 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 2602
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDA 439
TYA+++ P + + + + GD +P SP+ ++ + G G V G+
Sbjct: 1575 TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPG-IASTVKTGEE 1633
Query: 440 YTFSVDSPTS 469
F VD+ T+
Sbjct: 1634 VGFVVDAKTA 1643
Score = 30.3 bits (65), Expect = 5.4
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY I +T P + + +RF G +P SPF
Sbjct: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 1700
>AB209889-1|BAD93126.1| 1613|Homo sapiens filamin B, beta (actin
binding protein 278) variant protein.
Length = 1613
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRV--KDVAHGTVGKPVTFLV 182
A+F+PR G + ++V D P+P SP+ ++ D S ++ + G VGKP F +
Sbjct: 15 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 74
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +TV G
Sbjct: 75 DTKGAGTGGLGLTVEG 90
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 1354 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 1391
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHGT----VGKPVTF 176
++ E+ P G H + V D VPIP SPF + V + RV+ G KP F
Sbjct: 301 YQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVF 360
Query: 177 LVETMAAGPGNLEVTVNG 230
V T AG G L +TV G
Sbjct: 361 TVVTRGAGIGGLGITVEG 378
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARV 388
+G +CS G T ++S+ P P + V + F H+PGSPF + P++V
Sbjct: 89 EGPCEAKIECSDN-GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 147
Query: 389 IGAGSGEPPEKVSVGDAYTFSVD 457
+ +G G E VG+A SVD
Sbjct: 148 VASGPG--LEHGKVGEAGLLSVD 168
Score = 39.9 bits (89), Expect = 0.007
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L + V IP SPF + +D S + + HG VG+ V+
Sbjct: 110 YLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDC 169
Query: 189 MAAGPGNL 212
AGPG L
Sbjct: 170 SEAGPGAL 177
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 1351 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 1409
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 1410 TGIQSEFFINTTRAGPGTLSVTIEG 1434
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHGTVGKPV------TFL 179
AE++P A G++ +N+ IP SPF + V DV +A +G V +F
Sbjct: 396 AEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFT 455
Query: 180 VETMAAGPGNLEVTVNGGR 236
V++ AG LEV V G R
Sbjct: 456 VDSSKAGLAPLEVRVLGPR 474
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 1160 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 1192
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 1067 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 1106
Score = 36.3 bits (80), Expect = 0.082
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 239 TDCSGTQGAH-TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS---APARVIGAGSG 406
T+C T A TY + +TP + H VE+ ++ +P SPF V+ P+RV G G
Sbjct: 289 TECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPG 348
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 1261 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 1295
Score = 34.7 bits (76), Expect = 0.25
Identities = 15/67 (22%), Positives = 32/67 (47%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G + +G + C + T +++ P P +++ +++N H+PGSPF
Sbjct: 859 DAGEGGLDLAIEGPSKAEISCIDNKDG-TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTA 917
Query: 365 HVSAPAR 385
++ +R
Sbjct: 918 KITDDSR 924
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 1168 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 1227
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 1228 WTREAGAGGLSIAVEG 1243
Score = 33.9 bits (74), Expect = 0.44
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Frame = +2
Query: 284 FTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
+ P P + V + + G H+PGSPF V V P++V AG G V +F+V
Sbjct: 398 YIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPG-LGSGVRARVLQSFTV 456
Query: 455 DSPTSP----HVEVLGP 493
DS + V VLGP
Sbjct: 457 DSSKAGLAPLEVRVLGP 473
Score = 33.1 bits (72), Expect = 0.76
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G F PR+ + V++ ++G VPGSP+ S P++V G G E V
Sbjct: 9 GRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPG--LEGGLV 66
Query: 431 GDAYTFSVDS 460
G F++D+
Sbjct: 67 GKPAEFTIDT 76
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 977 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 1036
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 1037 DTRDAGYGGISLAVEG 1052
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ +++TP P+ V +++ + +P SPF V ++V +G G V
Sbjct: 486 GDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPA 545
Query: 431 GDAYTFSVDS 460
F++D+
Sbjct: 546 SLPVDFAIDA 555
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 975 ISFIPREVGEHLVSIKKNGNHVANSP 1000
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 1576 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 1613
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDA 439
TYA+++ P + + + + GD +P SP+ ++ + G G V G+
Sbjct: 586 TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPG-IASTVKTGEE 644
Query: 440 YTFSVDSPTS 469
F VD+ T+
Sbjct: 645 VGFVVDAKTA 654
Score = 30.3 bits (65), Expect = 5.4
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY I +T P + + +RF G +P SPF
Sbjct: 682 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 711
>AB191258-1|BAD52434.1| 2591|Homo sapiens filamin B protein.
Length = 2591
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVY---DVSAIRV--KDVAHGTVGKPVTFLV 182
A+F+PR G + ++V D P+P SP+ ++ D S ++ + G VGKP F +
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +TV G
Sbjct: 1064 DTKGAGTGGLGLTVEG 1079
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G Y + P P PH V++ F GD +P SPFV V P +G G P+ V
Sbjct: 409 KGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVR 468
Query: 428 VGDAYTFSVDSPTSPHVEVLGPARRPVLCKYLLKK 532
+ + F VD+ + E+ + P + L+K+
Sbjct: 469 IRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQ 503
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK----DVAHGTVGKPV 170
F ++VP A G + + VL S IPASPF +KV +D S ++ + A GKP
Sbjct: 807 FTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPT 866
Query: 171 TFLVETMAAGPGNLEVTVN 227
F V T AG L V N
Sbjct: 867 HFTVYTKGAGKAPLNVQFN 885
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 2332 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 2369
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHGT----VGKPVTF 176
++ E+ P G H + V D VPIP SPF + V + RV+ G KP F
Sbjct: 1290 YQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVF 1349
Query: 177 LVETMAAGPGNLEVTVNG 230
V T AG G L +TV G
Sbjct: 1350 TVVTRGAGIGGLGITVEG 1367
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARV 388
+G +CS G T ++S+ P P + V + F H+PGSPF + P++V
Sbjct: 1078 EGPCEAKIECSDN-GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 1136
Query: 389 IGAGSGEPPEKVSVGDAYTFSVD 457
+ +G G E VG+A SVD
Sbjct: 1137 VASGPG--LEHGKVGEAGLLSVD 1157
Score = 39.9 bits (89), Expect = 0.007
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L + V IP SPF + +D S + + HG VG+ V+
Sbjct: 1099 YLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDC 1158
Query: 189 MAAGPGNL 212
AGPG L
Sbjct: 1159 SEAGPGAL 1166
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 2329 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 2387
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 2388 TGIQSEFFINTTRAGPGTLSVTIEG 2412
Score = 39.5 bits (88), Expect = 0.009
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Frame = +3
Query: 18 AEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAHGTVGKPV------TFL 179
AE++P A G++ +N+ IP SPF + V DV +A +G V +F
Sbjct: 1385 AEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFT 1444
Query: 180 VETMAAGPGNLEVTVNGGR 236
V++ AG LEV V G R
Sbjct: 1445 VDSSKAGLAPLEVRVLGPR 1463
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
+++ + +TP V + + GD +P SPF V+AP + +V VG
Sbjct: 904 YSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQE 963
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLC 514
F+VD+ + V +L P+R+ V C
Sbjct: 964 FTVDTRGAGGQGKLDVTILSPSRKVVPC 991
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 2138 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 2170
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 2045 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 2084
Score = 36.3 bits (80), Expect = 0.082
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 239 TDCSGTQGAH-TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS---APARVIGAGSG 406
T+C T A TY + +TP + H VE+ ++ +P SPF V+ P+RV G G
Sbjct: 1278 TECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPG 1337
Score = 35.9 bits (79), Expect = 0.11
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHGT-VGKPVTFLVET 188
++ P G ++ V PIP SPF + V D+S I++ + + VGK F V+T
Sbjct: 909 KYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDT 968
Query: 189 M-AAGPGNLEVTV 224
A G G L+VT+
Sbjct: 969 RGAGGQGKLDVTI 981
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 2239 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 2273
Score = 34.7 bits (76), Expect = 0.25
Identities = 15/67 (22%), Positives = 32/67 (47%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G + +G + C + T +++ P P +++ +++N H+PGSPF
Sbjct: 1837 DAGEGGLDLAIEGPSKAEISCIDNKDG-TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTA 1895
Query: 365 HVSAPAR 385
++ +R
Sbjct: 1896 KITDDSR 1902
Score = 34.3 bits (75), Expect = 0.33
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSVGDA 439
TYA S+TP HT+ + + G ++P SP+ ++ S P +V G G + +
Sbjct: 703 TYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEP 762
Query: 440 YTFSVD 457
F+VD
Sbjct: 763 THFTVD 768
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 2146 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 2205
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 2206 WTREAGAGGLSIAVEG 2221
Score = 33.9 bits (74), Expect = 0.44
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Frame = +2
Query: 284 FTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
+ P P + V + + G H+PGSPF V V P++V AG G V +F+V
Sbjct: 1387 YIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPG-LGSGVRARVLQSFTV 1445
Query: 455 DSPTSP----HVEVLGP 493
DS + V VLGP
Sbjct: 1446 DSSKAGLAPLEVRVLGP 1462
Score = 33.1 bits (72), Expect = 0.76
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVSV 430
G F PR+ + V++ ++G VPGSP+ S P++V G G E V
Sbjct: 998 GRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPG--LEGGLV 1055
Query: 431 GDAYTFSVDS 460
G F++D+
Sbjct: 1056 GKPAEFTIDT 1065
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 1955 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 2014
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 2015 DTRDAGYGGISLAVEG 2030
Score = 31.9 bits (69), Expect = 1.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ +++TP P+ V +++ + +P SPF V ++V +G G V
Sbjct: 1475 GDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPA 1534
Query: 431 GDAYTFSVDS 460
F++D+
Sbjct: 1535 SLPVDFAIDA 1544
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 1953 ISFIPREVGEHLVSIKKNGNHVANSP 1978
Score = 31.5 bits (68), Expect = 2.3
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKDVAHGTVG----KPV 170
+R + P G H + + IP SPF ++V + +A R G +
Sbjct: 414 YRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETT 473
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V+T AAG G L VT+ G
Sbjct: 474 DFKVDTKAAGSGELGVTMKG 493
Score = 31.5 bits (68), Expect = 2.3
Identities = 12/37 (32%), Positives = 19/37 (51%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
YA + P P +++ + + G H+P SPF V A
Sbjct: 511 YAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEA 547
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 2554 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 2591
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDA 439
TYA+++ P + + + + GD +P SP+ ++ + G G V G+
Sbjct: 1575 TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPG-IASTVKTGEE 1633
Query: 440 YTFSVDSPTS 469
F VD+ T+
Sbjct: 1634 VGFVVDAKTA 1643
Score = 30.3 bits (65), Expect = 5.4
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY I +T P + + +RF G +P SPF
Sbjct: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 1700
>AJ012737-1|CAB46442.1| 2692|Homo sapiens filamin, muscle isoform
protein.
Length = 2692
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARV 388
+G +C G + A+S+ P +P +T+ + F H+PGSPF + V P++V
Sbjct: 1100 EGPCEAKIECQDN-GDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKV 1158
Query: 389 IGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEV 484
+G G E+ VG+A TF+VD + E+
Sbjct: 1159 RASGPG--LERGKVGEAATFTVDCSEAGEAEL 1188
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHG----TVGKPV 170
F ++ P G + + VL + IPASPFH+KV +D S ++ + VGKP
Sbjct: 829 FTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPT 888
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V T AG L+V G
Sbjct: 889 HFTVLTKGAGKAKLDVQFAG 908
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 1793 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 1852
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 1853 DAGEGGLSLAVEG 1865
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++Y + +T V + + GD VP SPFV +V+ P + KV+VG
Sbjct: 926 YSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQA 985
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLCK 517
FSV++ + V + P+RRP+ CK
Sbjct: 986 FSVNTRGAGGQGQLDVRMTSPSRRPIPCK 1014
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 2241 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 2269
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
+R ++ G H + VL D V +P SPF + V D + +R + G V K F
Sbjct: 1312 YRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRF 1371
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + + G
Sbjct: 1372 TVETRGAGTGGLGLAIEG 1389
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL---KVYDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L IP SPF V+D S +R + G VG+ TF V+
Sbjct: 1121 YLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDC 1180
Query: 189 MAAGPGNLEVTV 224
AG L + +
Sbjct: 1181 SEAGEAELTIEI 1192
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAH--------GTVGKPVTFL 179
F+P G H ++V + IP SPF ++V + S + GT G F+
Sbjct: 2435 FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFI 2494
Query: 180 VETMAAGPGNLEVTVNG 230
V T+ AG G L VT++G
Sbjct: 2495 VNTLNAGSGALSVTIDG 2511
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGK 164
+A+ FVP+ +G H + V +P SPF V + A +V+ + G G
Sbjct: 2239 SAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGV 2298
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F + T AG G L + V G
Sbjct: 2299 PAEFSIWTREAGAGGLSIAVEG 2320
Score = 39.5 bits (88), Expect = 0.009
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
+ I F P + H+++++FNG H+PGSPF V
Sbjct: 2431 HTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRV 2463
Score = 39.1 bits (87), Expect = 0.012
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G T+ ++ P PHTV + F G + SPF HVS P +G G P+ V
Sbjct: 431 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGPQPKGVR 490
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 491 VKEVADFKV 499
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 1972 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 2031
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2032 DTRNAGYGGLGLSIEG 2047
Score = 38.3 bits (85), Expect = 0.020
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRV----KDVAHGTVGKPVTFLVET 188
++P G +++++ D P+P SPF ++ V +V + G VG P F ++T
Sbjct: 1028 YMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDT 1087
Query: 189 MAAGPGNLEVTVNG 230
A G L +TV G
Sbjct: 1088 KGADTGGLGLTVEG 1101
Score = 38.3 bits (85), Expect = 0.020
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHG-----TVGKPVTFLV 182
E++P G++ +N+ PIP SPF + V D V +VK G P TF V
Sbjct: 1408 EYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTV 1467
Query: 183 ETMAAGPGNLEVTVNGGRVPTAAA 254
+ AG L+V V G PT A
Sbjct: 1468 DCSQAGRAPLQVAVLG---PTGVA 1488
Score = 37.9 bits (84), Expect = 0.027
Identities = 15/57 (26%), Positives = 30/57 (52%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
+G + +C + T ++++P +P + + ++F HVPGSPF V+ R+
Sbjct: 2046 EGPSKVDINCEDMEDG-TCKVTYSPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRM 2101
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSV 430
G T+ S+ P P HT+ + + G +VP SPF +V S P RV G G +
Sbjct: 722 GDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKA 781
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 782 NEPTYFTVD 790
Score = 36.7 bits (81), Expect = 0.062
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH---VSAPARVIGAGSGEPPEKVSV 430
GA A+ + P + P+ V++ ++G VPGSPF P++V G G + V
Sbjct: 1020 GAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPG--LKGGLV 1077
Query: 431 GDAYTFSVDS 460
G FS+D+
Sbjct: 1078 GTPAPFSIDT 1087
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 1701 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 1734
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 1853 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 1911
Query: 365 HVS 373
++
Sbjct: 1912 KIT 1914
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
+S+ ++P + V ++FN +H+P SPFV V++
Sbjct: 2338 VSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVAS 2370
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 1788 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 1847
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 1848 TIVTKDAGEGGLSLAVEGPSKAEITCK 1874
Score = 34.7 bits (76), Expect = 0.25
Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKDVAHGTVGKPV-- 170
+ FR + P G H ++V PI SPF + V + +A R G V
Sbjct: 434 STFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGPQPKGVRVKE 493
Query: 171 --TFLVETMAAGPGNLEVTVNG 230
F V T AG G L+VTV G
Sbjct: 494 VADFKVFTKGAGSGELKVTVKG 515
Score = 34.7 bits (76), Expect = 0.25
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH 367
G TY +S+ P +T+ +++ GD +P SPF H
Sbjct: 1594 GDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 1629
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 1970 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 2026
Score = 33.5 bits (73), Expect = 0.58
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ + +TP P+TV +++ VP SPF V ++V +G G +
Sbjct: 1497 GDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPA 1556
Query: 431 GDAYTFSVDSPTSPH----VEVLGPARRP 505
F++D+ + V++L P +P
Sbjct: 1557 SLPVEFTIDARDAGEGLLTVQILDPEGKP 1585
Score = 33.1 bits (72), Expect = 0.76
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV----YDVSAIRVKDVAHGTVG----KP 167
+ +VP+ G H++ VL I SPF + V D + + + VG KP
Sbjct: 336 YAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKP 395
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G++ V +
Sbjct: 396 TYFDIYTAGAGTGDVAVVI 414
Score = 31.1 bits (67), Expect = 3.1
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVKDVAHGT------VGKPV 170
FR +VP +H + + V +P SPF + V + S RVK G +P
Sbjct: 726 FRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPT 785
Query: 171 TFLVETMAAGPGNLEVTV 224
F V+ AG G++ + +
Sbjct: 786 YFTVDCSEAGQGDVSIGI 803
Score = 30.7 bits (66), Expect = 4.1
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTF 448
+ + P P + V + F G +PGSPF V V P +V +G G V TF
Sbjct: 1407 VEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPG-LGAGVRARVPQTF 1465
Query: 449 SVD---SPTSP-HVEVLGP 493
+VD + +P V VLGP
Sbjct: 1466 TVDCSQAGRAPLQVAVLGP 1484
Score = 30.3 bits (65), Expect = 5.4
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TYA+S+ P+ H V + F G ++ SPF +V
Sbjct: 335 TYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNV 368
>AF252549-1|AAF67190.1| 2725|Homo sapiens gamma-filamin protein.
Length = 2725
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARV 388
+G +C G + A+S+ P +P +T+ + F H+PGSPF + V P++V
Sbjct: 1100 EGPCEAKIECQDN-GDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKV 1158
Query: 389 IGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEV 484
+G G E+ VG+A TF+VD + E+
Sbjct: 1159 RASGPG--LERGKVGEAATFTVDCSEAGEAEL 1188
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHG----TVGKPV 170
F ++ P G + + VL + IPASPFH+KV +D S ++ + VGKP
Sbjct: 829 FTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPT 888
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V T AG L+V G
Sbjct: 889 HFTVLTKGAGKAKLDVQFAG 908
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 1826 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 1885
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 1886 DAGEGGLSLAVEG 1898
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++Y + +T V + + GD VP SPFV +V+ P + KV+VG
Sbjct: 926 YSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQA 985
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLCK 517
FSV++ + V + P+RRP+ CK
Sbjct: 986 FSVNTRGAGGQGQLDVRMTSPSRRPIPCK 1014
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 2274 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 2302
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
+R ++ G H + VL D V +P SPF + V D + +R + G V K F
Sbjct: 1312 YRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRF 1371
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + + G
Sbjct: 1372 TVETRGAGTGGLGLAIEG 1389
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL---KVYDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L IP SPF V+D S +R + G VG+ TF V+
Sbjct: 1121 YLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDC 1180
Query: 189 MAAGPGNLEVTV 224
AG L + +
Sbjct: 1181 SEAGEAELTIEI 1192
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAH--------GTVGKPVTFL 179
F+P G H ++V + IP SPF ++V + S + GT G F+
Sbjct: 2468 FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFI 2527
Query: 180 VETMAAGPGNLEVTVNG 230
V T+ AG G L VT++G
Sbjct: 2528 VNTLNAGSGALSVTIDG 2544
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRV----KDVAHGTVGKPVTFLVET 188
++P G +++++ D P+P SPF ++ V +V + G VG P F ++T
Sbjct: 1028 YMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDT 1087
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1088 KGAGTGGLGLTVEG 1101
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGK 164
+A+ FVP+ +G H + V +P SPF V + A +V+ + G G
Sbjct: 2272 SAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGV 2331
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F + T AG G L + V G
Sbjct: 2332 PAEFSIWTREAGAGGLSIAVEG 2353
Score = 39.5 bits (88), Expect = 0.009
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
+ I F P + H+++++FNG H+PGSPF V
Sbjct: 2464 HTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRV 2496
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 2005 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 2064
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2065 DTRNAGYGGLGLSIEG 2080
Score = 38.3 bits (85), Expect = 0.020
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G T+ ++ P PHTV + F G + SPF HVS P +G G P+ V
Sbjct: 431 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVR 490
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 491 VKEVADFKV 499
Score = 38.3 bits (85), Expect = 0.020
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHG-----TVGKPVTFLV 182
E++P G++ +N+ PIP SPF + V D V +VK G P TF V
Sbjct: 1408 EYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTV 1467
Query: 183 ETMAAGPGNLEVTVNGGRVPTAAA 254
+ AG L+V V G PT A
Sbjct: 1468 DCSQAGRAPLQVAVLG---PTGVA 1488
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSV 430
G T+ S+ P P HT+ + + G +VP SPF +V S P RV G G +
Sbjct: 722 GDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKA 781
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 782 NEPTYFTVD 790
Score = 37.1 bits (82), Expect = 0.047
Identities = 15/57 (26%), Positives = 29/57 (50%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
+G + +C + T +++ P +P + + ++F HVPGSPF V+ R+
Sbjct: 2079 EGPSKVDINCEDMEDG-TCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRM 2134
Score = 36.7 bits (81), Expect = 0.062
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH---VSAPARVIGAGSGEPPEKVSV 430
GA A+ + P + P+ V++ ++G VPGSPF P++V G G + V
Sbjct: 1020 GAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPG--LKGGLV 1077
Query: 431 GDAYTFSVDS 460
G FS+D+
Sbjct: 1078 GTPAPFSIDT 1087
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 1701 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 1734
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 1886 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 1944
Query: 365 HVS 373
++
Sbjct: 1945 KIT 1947
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
+S+ ++P + V ++FN +H+P SPFV V++
Sbjct: 2371 VSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVAS 2403
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 1821 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 1880
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 1881 TIVTKDAGEGGLSLAVEGPSKAEITCK 1907
Score = 34.7 bits (76), Expect = 0.25
Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKD---VAHGTVGKP 167
+ FR + P G H ++V PI SPF + V + +A R G K
Sbjct: 434 STFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKE 493
Query: 168 VT-FLVETMAAGPGNLEVTVNG 230
V F V T AG G L+VTV G
Sbjct: 494 VADFKVFTKGAGSGELKVTVKG 515
Score = 34.7 bits (76), Expect = 0.25
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH 367
G TY +S+ P +T+ +++ GD +P SPF H
Sbjct: 1594 GDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 1629
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 2003 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 2059
Score = 33.5 bits (73), Expect = 0.58
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ + +TP P+TV +++ VP SPF V ++V +G G +
Sbjct: 1497 GDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPA 1556
Query: 431 GDAYTFSVDSPTSPH----VEVLGPARRP 505
F++D+ + V++L P +P
Sbjct: 1557 SLPVEFTIDARDAGEGLLTVQILDPEGKP 1585
Score = 33.1 bits (72), Expect = 0.76
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV----YDVSAIRVKDVAHGTVG----KP 167
+ +VP+ G H++ VL I SPF + V D + + + VG KP
Sbjct: 336 YAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKP 395
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G++ V +
Sbjct: 396 TYFDIYTAGAGTGDVAVVI 414
Score = 31.1 bits (67), Expect = 3.1
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVKDVAHGT------VGKPV 170
FR +VP +H + + V +P SPF + V + S RVK G +P
Sbjct: 726 FRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPT 785
Query: 171 TFLVETMAAGPGNLEVTV 224
F V+ AG G++ + +
Sbjct: 786 YFTVDCSEAGQGDVSIGI 803
Score = 30.7 bits (66), Expect = 4.1
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTF 448
+ + P P + V + F G +PGSPF V V P +V +G G V TF
Sbjct: 1407 VEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPG-LGAGVRARVPQTF 1465
Query: 449 SVD---SPTSP-HVEVLGP 493
+VD + +P V VLGP
Sbjct: 1466 TVDCSQAGRAPLQVAVLGP 1484
Score = 30.3 bits (65), Expect = 5.4
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TYA+S+ P+ H V + F G ++ SPF +V
Sbjct: 335 TYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNV 368
>AF184126-1|AAF68195.1| 2705|Homo sapiens filamin 2 protein.
Length = 2705
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARV 388
+G +C G + A+S+ P +P +T+ + F H+PGSPF + V P++V
Sbjct: 1080 EGPCEAKIECQDN-GDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKV 1138
Query: 389 IGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEV 484
+G G E+ VG+A TF+VD + E+
Sbjct: 1139 RASGPG--LERGKVGEAATFTVDCSEAGEAEL 1168
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHG----TVGKPV 170
F ++ P G + + VL + IPASPFH+KV +D S ++ + VGKP
Sbjct: 809 FTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPT 868
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V T AG L+V G
Sbjct: 869 HFTVLTKGAGKAKLDVQFAG 888
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 1806 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 1865
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 1866 DAGEGGLSLAVEG 1878
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++Y + +T V + + GD VP SPFV +V+ P + KV+VG
Sbjct: 906 YSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQA 965
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLCK 517
FSV++ + V + P+RRP+ CK
Sbjct: 966 FSVNTRGAGGQGQLDVRMTSPSRRPIPCK 994
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 2254 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 2282
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
+R ++ G H + VL D V +P SPF + V D + +R + G V K F
Sbjct: 1292 YRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRF 1351
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + + G
Sbjct: 1352 TVETRGAGTGGLGLAIEG 1369
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL---KVYDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L IP SPF V+D S +R + G VG+ TF V+
Sbjct: 1101 YLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDC 1160
Query: 189 MAAGPGNLEVTV 224
AG L + +
Sbjct: 1161 SEAGEAELTIEI 1172
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAH--------GTVGKPVTFL 179
F+P G H ++V + IP SPF ++V + S + GT G F+
Sbjct: 2448 FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFI 2507
Query: 180 VETMAAGPGNLEVTVNG 230
V T+ AG G L VT++G
Sbjct: 2508 VNTLNAGSGALSVTIDG 2524
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRV----KDVAHGTVGKPVTFLVET 188
++P G +++++ D P+P SPF ++ V +V + G VG P F ++T
Sbjct: 1008 YMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDT 1067
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1068 KGAGTGGLGLTVEG 1081
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGK 164
+A+ FVP+ +G H + V +P SPF V + A +V+ + G G
Sbjct: 2252 SAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGRAGLERGVAGV 2311
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F + T AG G L + V G
Sbjct: 2312 PAEFSIWTREAGAGGLSIAVEG 2333
Score = 39.5 bits (88), Expect = 0.009
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
+ I F P + H+++++FNG H+PGSPF V
Sbjct: 2444 HTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRV 2476
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 1985 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 2044
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2045 DTRNAGYGGLGLSIEG 2060
Score = 38.3 bits (85), Expect = 0.020
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G T+ ++ P PHTV + F G + SPF HVS P +G G P+ V
Sbjct: 411 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVR 470
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 471 VKEVADFKV 479
Score = 38.3 bits (85), Expect = 0.020
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHG-----TVGKPVTFLV 182
E++P G++ +N+ PIP SPF + V D V +VK G P TF V
Sbjct: 1388 EYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTV 1447
Query: 183 ETMAAGPGNLEVTVNGGRVPTAAA 254
+ AG L+V V G PT A
Sbjct: 1448 DCSQAGRAPLQVAVLG---PTGVA 1468
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSV 430
G T+ S+ P P HT+ + + G +VP SPF +V S P RV G G +
Sbjct: 702 GNGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKA 761
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 762 NEPTYFTVD 770
Score = 37.1 bits (82), Expect = 0.047
Identities = 15/57 (26%), Positives = 29/57 (50%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
+G + +C + T +++ P +P + + ++F HVPGSPF V+ R+
Sbjct: 2059 EGPSKVDINCEDMEDG-TCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRM 2114
Score = 36.7 bits (81), Expect = 0.062
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH---VSAPARVIGAGSGEPPEKVSV 430
GA A+ + P + P+ V++ ++G VPGSPF P++V G G + V
Sbjct: 1000 GAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPG--LKGGLV 1057
Query: 431 GDAYTFSVDS 460
G FS+D+
Sbjct: 1058 GTPAPFSIDT 1067
Score = 36.3 bits (80), Expect = 0.082
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ + +TP P+TV +++ VP SPF V ++V +G G +
Sbjct: 1477 GDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPA 1536
Query: 431 GDAYTFSVDSPTSPH----VEVLGPARRP 505
F++D+ + V++LGP +P
Sbjct: 1537 SLPVEFTIDARDAGEGLLTVQILGPEGKP 1565
Score = 36.3 bits (80), Expect = 0.082
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH 367
G TYA+S+ P +T+ +++ GD +P SPF H
Sbjct: 1574 GDGTYAVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 1609
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 1681 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 1714
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 1866 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 1924
Query: 365 HVS 373
++
Sbjct: 1925 KIT 1927
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
+S+ ++P + V ++FN +H+P SPFV V++
Sbjct: 2351 VSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVAS 2383
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 1801 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 1860
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 1861 TIVTKDAGEGGLSLAVEGPSKAEITCK 1887
Score = 34.7 bits (76), Expect = 0.25
Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKD---VAHGTVGKP 167
+ FR + P G H ++V PI SPF + V + +A R G K
Sbjct: 414 STFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKE 473
Query: 168 VT-FLVETMAAGPGNLEVTVNG 230
V F V T AG G L+VTV G
Sbjct: 474 VADFKVFTKGAGSGELKVTVKG 495
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 1983 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 2039
Score = 33.1 bits (72), Expect = 0.76
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV----YDVSAIRVKDVAHGTVG----KP 167
+ +VP+ G H++ VL I SPF + V D + + + VG KP
Sbjct: 316 YAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKP 375
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G++ V +
Sbjct: 376 TYFDIYTAGAGTGDVAVVI 394
Score = 31.1 bits (67), Expect = 3.1
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVKDVAHGT------VGKPV 170
FR +VP +H + + V +P SPF + V + S RVK G +P
Sbjct: 706 FRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPT 765
Query: 171 TFLVETMAAGPGNLEVTV 224
F V+ AG G++ + +
Sbjct: 766 YFTVDCSEAGQGDVSIGI 783
Score = 30.7 bits (66), Expect = 4.1
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTF 448
+ + P P + V + F G +PGSPF V V P +V +G G V TF
Sbjct: 1387 VEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPG-LGAGVRARVPQTF 1445
Query: 449 SVD---SPTSP-HVEVLGP 493
+VD + +P V VLGP
Sbjct: 1446 TVDCSQAGRAPLQVAVLGP 1464
Score = 30.3 bits (65), Expect = 5.4
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TYA+S+ P+ H V + F G ++ SPF +V
Sbjct: 315 TYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNV 348
>AF146692-1|AAF80245.1| 2691|Homo sapiens filamin 2 protein.
Length = 2691
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARV 388
+G +C G + A+S+ P +P +T+ + F H+PGSPF + V P++V
Sbjct: 1100 EGPCEAKIECQDN-GDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKV 1158
Query: 389 IGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEV 484
+G G E+ VG+A TF+VD + E+
Sbjct: 1159 RASGPG--LERGKVGEAATFTVDCSEAGEAEL 1188
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHG----TVGKPV 170
F ++ P G + + VL + IPASPFH+KV +D S ++ + VGKP
Sbjct: 829 FTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPT 888
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V T AG L+V G
Sbjct: 889 HFTVLTKGAGKAKLDVQFAG 908
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 1793 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 1852
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 1853 DAGEGGLSLAVEG 1865
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++Y + +T V + + GD VP SPFV +V+ P + KV+VG
Sbjct: 926 YSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQA 985
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLCK 517
FSV++ + V + P+RRP+ CK
Sbjct: 986 FSVNTRGAGGQGQLDVRMTSPSRRPIPCK 1014
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 2241 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 2269
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
+R ++ G H + VL D V +P SPF + V D + +R + G V K F
Sbjct: 1312 YRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRF 1371
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + + G
Sbjct: 1372 TVETRGAGTGGLGLAIEG 1389
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL---KVYDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L IP SPF V+D S +R + G VG+ TF V+
Sbjct: 1121 YLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDC 1180
Query: 189 MAAGPGNLEVTV 224
AG L + +
Sbjct: 1181 SEAGEAELTIEI 1192
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRV----KDVAHGTVGKPVTFLVET 188
++P G +++++ D P+P SPF ++ V +V + G VG P F ++T
Sbjct: 1028 YMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDT 1087
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1088 KGAGTGGLGLTVEG 1101
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGK 164
+A+ FVP+ +G H + V +P SPF V + A +V+ + G G
Sbjct: 2239 SAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGV 2298
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F + T AG G L + V G
Sbjct: 2299 PAEFSIWTREAGAGGLSIAVEG 2320
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 1972 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 2031
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2032 DTRNAGYGGLGLSIEG 2047
Score = 38.3 bits (85), Expect = 0.020
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G T+ ++ P PHTV + F G + SPF HVS P +G G P+ V
Sbjct: 431 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVR 490
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 491 VKEVADFKV 499
Score = 38.3 bits (85), Expect = 0.020
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHG-----TVGKPVTFLV 182
E++P G++ +N+ PIP SPF + V D V +VK G P TF V
Sbjct: 1408 EYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTV 1467
Query: 183 ETMAAGPGNLEVTVNGGRVPTAAA 254
+ AG L+V V G PT A
Sbjct: 1468 DCSQAGRAPLQVAVLG---PTGVA 1488
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSV 430
G T+ S+ P P HT+ + + G +VP SPF +V S P RV G G +
Sbjct: 722 GDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKA 781
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 782 NEPTYFTVD 790
Score = 37.1 bits (82), Expect = 0.047
Identities = 15/57 (26%), Positives = 29/57 (50%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
+G + +C + T +++ P +P + + ++F HVPGSPF V+ R+
Sbjct: 2046 EGPSKVDINCEDMEDG-TCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRM 2101
Score = 36.7 bits (81), Expect = 0.062
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH---VSAPARVIGAGSGEPPEKVSV 430
GA A+ + P + P+ V++ ++G VPGSPF P++V G G + V
Sbjct: 1020 GAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPG--LKGGLV 1077
Query: 431 GDAYTFSVDS 460
G FS+D+
Sbjct: 1078 GTPAPFSIDT 1087
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 1701 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 1734
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 1853 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 1911
Query: 365 HVS 373
++
Sbjct: 1912 KIT 1914
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
+S+ ++P + V ++FN +H+P SPFV V++
Sbjct: 2338 VSYVVQEPGDYKVSIKFNDEHIPDSPFVVPVAS 2370
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 1788 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 1847
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 1848 TIVTKDAGEGGLSLAVEGPSKAEITCK 1874
Score = 34.7 bits (76), Expect = 0.25
Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKD---VAHGTVGKP 167
+ FR + P G H ++V PI SPF + V + +A R G K
Sbjct: 434 STFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKE 493
Query: 168 VT-FLVETMAAGPGNLEVTVNG 230
V F V T AG G L+VTV G
Sbjct: 494 VADFKVFTKGAGSGELKVTVKG 515
Score = 34.7 bits (76), Expect = 0.25
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH 367
G TY +S+ P +T+ +++ GD +P SPF H
Sbjct: 1594 GDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 1629
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 1970 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 2026
Score = 33.5 bits (73), Expect = 0.58
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ + +TP P+TV +++ VP SPF V ++V +G G +
Sbjct: 1497 GDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPA 1556
Query: 431 GDAYTFSVDSPTSPH----VEVLGPARRP 505
F++D+ + V++L P +P
Sbjct: 1557 SLPVEFTIDARDAGEGLLTVQILDPEGKP 1585
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV----YDVSAIRVKDVAHGTVG----KP 167
+ +VP+ G H++ VL I SPF + V D + + + VG KP
Sbjct: 336 YAVXYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKP 395
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G++ V +
Sbjct: 396 TYFDIYTAGAGTGDVAVVI 414
Score = 31.9 bits (69), Expect = 1.8
Identities = 12/33 (36%), Positives = 20/33 (60%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
+ I F P + H+++++FN H+PGS F V
Sbjct: 2431 HTIRFIPHENGVHSIDVKFNCAHIPGSLFKIRV 2463
Score = 31.9 bits (69), Expect = 1.8
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS--------AIRVKDVAHGTVGKPVTFL 179
F+P G H ++V + IP S F ++V + S + ++ GT G F+
Sbjct: 2435 FIPHENGVHSIDVKFNCAHIPGSLFKIRVGEHSQAGDPGLVSAYGPELXGGTTGVSSEFI 2494
Query: 180 VETMAAGPGNLEVTVNG 230
+ + AG G L VT++G
Sbjct: 2495 DDHLNAGFGALSVTIDG 2511
Score = 31.1 bits (67), Expect = 3.1
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVKDVAHGT------VGKPV 170
FR +VP +H + + V +P SPF + V + S RVK G +P
Sbjct: 726 FRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPT 785
Query: 171 TFLVETMAAGPGNLEVTV 224
F V+ AG G++ + +
Sbjct: 786 YFTVDCSEAGQGDVSIGI 803
Score = 30.7 bits (66), Expect = 4.1
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTF 448
+ + P P + V + F G +PGSPF V V P +V +G G V TF
Sbjct: 1407 VEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPG-LGAGVRARVPQTF 1465
Query: 449 SVD---SPTSP-HVEVLGP 493
+VD + +P V VLGP
Sbjct: 1466 TVDCSQAGRAPLQVAVLGP 1484
>AF089841-1|AAD12245.1| 2705|Homo sapiens gamma-filamin protein.
Length = 2705
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARV 388
+G +C G + A+S+ P +P +T+ + F H+PGSPF + V P++V
Sbjct: 1080 EGPCEAKIECQDN-GDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKV 1138
Query: 389 IGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEV 484
+G G E+ VG+A TF+VD + E+
Sbjct: 1139 RASGPG--LERGKVGEAATFTVDCSEAGEAEL 1168
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRVKDVAHG----TVGKPV 170
F ++ P G + + VL + IPASPFH+KV +D S ++ + VGKP
Sbjct: 809 FTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPT 868
Query: 171 TFLVETMAAGPGNLEVTVNG 230
F V T AG L+V G
Sbjct: 869 HFTVLTKGAGKAKLDVQFAG 888
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 1806 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 1865
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 1866 DAGEGGLSLAVEG 1878
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYT 445
++Y + +T V + + GD VP SPFV +V+ P + KV+VG
Sbjct: 906 YSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQA 965
Query: 446 FSVDSPTSP-----HVEVLGPARRPVLCK 517
FSV++ + V + P+RRP+ CK
Sbjct: 966 FSVNTRGAGGQGQLDVRMTSPSRRPIPCK 994
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 2254 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 2282
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV---YDVSAIRV--KDVAHGTVGKPVTF 176
+R ++ G H + VL D V +P SPF + V D + +R + G V K F
Sbjct: 1292 YRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRF 1351
Query: 177 LVETMAAGPGNLEVTVNG 230
VET AG G L + + G
Sbjct: 1352 TVETRGAGTGGLGLAIEG 1369
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL---KVYDVSAIRVK--DVAHGTVGKPVTFLVET 188
++P GE+ +N+L IP SPF V+D S +R + G VG+ TF V+
Sbjct: 1101 YLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDC 1160
Query: 189 MAAGPGNLEVTV 224
AG L + +
Sbjct: 1161 SEAGEAELTIEI 1172
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAH--------GTVGKPVTFL 179
F+P G H ++V + IP SPF ++V + S + GT G F+
Sbjct: 2448 FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFI 2507
Query: 180 VETMAAGPGNLEVTVNG 230
V T+ AG G L VT++G
Sbjct: 2508 VNTLNAGSGALSVTIDG 2524
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLK-VYDVSAIRV----KDVAHGTVGKPVTFLVET 188
++P G +++++ D P+P SPF ++ V +V + G VG P F ++T
Sbjct: 1008 YMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDT 1067
Query: 189 MAAGPGNLEVTVNG 230
AG G L +TV G
Sbjct: 1068 KGAGTGGLGLTVEG 1081
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGK 164
+A+ FVP+ +G H + V +P SPF V + A +V+ + G G
Sbjct: 2252 SAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGRAGLERGVAGV 2311
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F + T AG G L + V G
Sbjct: 2312 PAEFSIWTREAGAGGLSIAVEG 2333
Score = 39.5 bits (88), Expect = 0.009
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
+ I F P + H+++++FNG H+PGSPF V
Sbjct: 2444 HTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRV 2476
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 1985 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 2044
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 2045 DTRNAGYGGLGLSIEG 2060
Score = 38.3 bits (85), Expect = 0.020
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Frame = +2
Query: 257 QGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA---PARVIGAGSGEPPEKVS 427
+G T+ ++ P PHTV + F G + SPF HVS P +G G P+ V
Sbjct: 411 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVR 470
Query: 428 VGDAYTFSV 454
V + F V
Sbjct: 471 VKEVADFKV 479
Score = 38.3 bits (85), Expect = 0.020
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHG-----TVGKPVTFLV 182
E++P G++ +N+ PIP SPF + V D V +VK G P TF V
Sbjct: 1388 EYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTV 1447
Query: 183 ETMAAGPGNLEVTVNGGRVPTAAA 254
+ AG L+V V G PT A
Sbjct: 1448 DCSQAGRAPLQVAVLG---PTGVA 1468
Score = 37.1 bits (82), Expect = 0.047
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV---SAPARVIGAGSGEPPEKVSV 430
G T+ S+ P P HT+ + + G +VP SPF +V S P RV G G +
Sbjct: 702 GNGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKA 761
Query: 431 GDAYTFSVD 457
+ F+VD
Sbjct: 762 NEPTYFTVD 770
Score = 37.1 bits (82), Expect = 0.047
Identities = 15/57 (26%), Positives = 29/57 (50%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
+G + +C + T +++ P +P + + ++F HVPGSPF V+ R+
Sbjct: 2059 EGPSKVDINCEDMEDG-TCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRM 2114
Score = 36.7 bits (81), Expect = 0.062
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH---VSAPARVIGAGSGEPPEKVSV 430
GA A+ + P + P+ V++ ++G VPGSPF P++V G G + V
Sbjct: 1000 GAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPG--LKGGLV 1057
Query: 431 GDAYTFSVDS 460
G FS+D+
Sbjct: 1058 GTPAPFSIDT 1067
Score = 36.3 bits (80), Expect = 0.082
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ + +TP P+TV +++ VP SPF V ++V +G G +
Sbjct: 1477 GDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPA 1536
Query: 431 GDAYTFSVDSPTSPH----VEVLGPARRP 505
F++D+ + V++LGP +P
Sbjct: 1537 SLPVEFTIDARDAGEGLLTVQILGPEGKP 1565
Score = 36.3 bits (80), Expect = 0.082
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH 367
G TYA+S+ P +T+ +++ GD +P SPF H
Sbjct: 1574 GDGTYAVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 1609
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 1681 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 1714
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 1866 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 1924
Query: 365 HVS 373
++
Sbjct: 1925 KIT 1927
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
+S+ ++P + V ++FN +H+P SPFV V++
Sbjct: 2351 VSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVAS 2383
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 1801 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 1860
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 1861 TIVTKDAGEGGLSLAVEGPSKAEITCK 1887
Score = 34.7 bits (76), Expect = 0.25
Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVKD---VAHGTVGKP 167
+ FR + P G H ++V PI SPF + V + +A R G K
Sbjct: 414 STFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKE 473
Query: 168 VT-FLVETMAAGPGNLEVTVNG 230
V F V T AG G L+VTV G
Sbjct: 474 VADFKVFTKGAGSGELKVTVKG 495
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 1983 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 2039
Score = 33.1 bits (72), Expect = 0.76
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKV----YDVSAIRVKDVAHGTVG----KP 167
+ +VP+ G H++ VL I SPF + V D + + + VG KP
Sbjct: 316 YAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKP 375
Query: 168 VTFLVETMAAGPGNLEVTV 224
F + T AG G++ V +
Sbjct: 376 TYFDIYTAGAGTGDVAVVI 394
Score = 31.1 bits (67), Expect = 3.1
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVKDVAHGT------VGKPV 170
FR +VP +H + + V +P SPF + V + S RVK G +P
Sbjct: 706 FRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPT 765
Query: 171 TFLVETMAAGPGNLEVTV 224
F V+ AG G++ + +
Sbjct: 766 YFTVDCSEAGQGDVSIGI 783
Score = 30.7 bits (66), Expect = 4.1
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTF 448
+ + P P + V + F G +PGSPF V V P +V +G G V TF
Sbjct: 1387 VEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPG-LGAGVRARVPQTF 1445
Query: 449 SVD---SPTSP-HVEVLGP 493
+VD + +P V VLGP
Sbjct: 1446 TVDCSQAGRAPLQVAVLGP 1464
Score = 30.3 bits (65), Expect = 5.4
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TYA+S+ P+ H V + F G ++ SPF +V
Sbjct: 315 TYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNV 348
>BC067111-1|AAH67111.1| 983|Homo sapiens FLNA protein protein.
Length = 983
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 168 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 227
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 228 DAGEGGLSLAIEG 240
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 532 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 562
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 724 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 759
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 724 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 782
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 783 PAEFVVNTSNAGAGALSVTIDG 804
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 347 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 406
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 407 DTRDAGYGGLSLSIEG 422
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 228 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 286
Query: 365 HVS 373
V+
Sbjct: 287 RVT 289
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 437 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 476
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 631 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 665
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 538 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 597
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 598 WTREAGAGGLAIAVEG 613
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 43 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 72
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 946 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 978
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 345 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 376
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 163 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 196
>BC014654-1|AAH14654.1| 838|Homo sapiens FLNA protein protein.
Length = 838
Score = 47.6 bits (108), Expect = 3e-05
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 23 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 82
Query: 192 AAGPGNLEVTVNG 230
AG G L + + G
Sbjct: 83 DAGEGGLSLAIEG 95
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 387 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 417
Score = 44.4 bits (100), Expect = 3e-04
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
YA+ F PR+ + ++++FNG H+PGSPF V P
Sbjct: 579 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEP 614
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGTVGK 164
+ F+PR G + ++V + IP SPF ++V + VSA + G G
Sbjct: 579 YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGA-GLEGGVTGN 637
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F+V T AG G L VT++G
Sbjct: 638 PAEFVVNTSNAGAGALSVTIDG 659
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVL-----IDSVPIPASPFHLKVYDVSAIRV--KDVAHGTVGKPVTFLV 182
FVP+ GEH ++V + S PIP ++ D S +RV + + G +P F++
Sbjct: 202 FVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFII 261
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 262 DTRDAGYGGLSLSIEG 277
Score = 37.5 bits (83), Expect = 0.035
Identities = 18/63 (28%), Positives = 31/63 (49%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C+ Q T ++S+ P P +++ +++N HVPGSPF
Sbjct: 83 DAGEGGLSLAIEGPSKAEISCTDNQDG-TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTA 141
Query: 365 HVS 373
V+
Sbjct: 142 RVT 144
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 292 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 331
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 486 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 520
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 393 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 452
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 453 WTREAGAGGLAIAVEG 468
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 801 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 833
Score = 31.1 bits (67), Expect = 3.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVS 373
ISF P++ H V ++ NG HV SP +S
Sbjct: 200 ISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 231
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 18 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 51
>BX664723-4|CAI43200.2| 281|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 281
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 136 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 166
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 235 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 269
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 142 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 201
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 202 WTREAGAGGLAIAVEG 217
>BC109289-1|AAI09290.3| 307|Homo sapiens FLNA protein protein.
Length = 307
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 266 HTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
HTY I F P + HTV +++ G HVPGSPF
Sbjct: 113 HTYCIRFVPAEMGTHTVSVKYKGQHVPGSPF 143
Score = 36.7 bits (81), Expect = 0.062
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +++ P +P + + ++F HVPGSPF V+ RV
Sbjct: 18 TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRV 57
Score = 36.7 bits (81), Expect = 0.062
Identities = 12/35 (34%), Positives = 25/35 (71%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+++ ++P + V ++FN +H+P SPFV V++P+
Sbjct: 212 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 246
Score = 34.7 bits (76), Expect = 0.25
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP +G H ++V +P SPF V + A +V+ + G P F +
Sbjct: 119 FVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSI 178
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 179 WTREAGAGGLAIAVEG 194
>X70084-1|CAA49689.1| 431|Homo sapiens filamin protein.
Length = 431
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 156 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 215
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 216 DAGEGGLSLAVEG 228
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 335 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 394
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 395 DTRNAGYGGLGLSIEG 410
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 64 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 97
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 216 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 274
Query: 365 HVS 373
++
Sbjct: 275 KIT 277
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 151 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 210
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 211 TIVTKDAGEGGLSLAVEGPSKAEITCK 237
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 333 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 389
>AL137574-1|CAB70818.1| 729|Homo sapiens hypothetical protein
protein.
Length = 729
Score = 45.2 bits (102), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 470 YAVRFIPHENGAHTIDVKFNGSHVVGSPFKVRVGEPGQ 507
Score = 40.3 bits (90), Expect = 0.005
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 467 PDKYAVRFIPHENGAHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 525
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 526 TGIQSEFFINTTRAGPGTLSVTIEG 550
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 276 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 308
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 183 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 222
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 377 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 411
Score = 34.3 bits (75), Expect = 0.33
Identities = 11/39 (28%), Positives = 24/39 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
T +++ P P +++ +++N H+PGSPF ++ +R
Sbjct: 2 TCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 40
Score = 34.3 bits (75), Expect = 0.33
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 284 FVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 343
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 344 WTREAGAGGLSIAVEG 359
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 93 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 152
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 153 DTRDAGYGGISLAVEG 168
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 91 ISFIPREVGEHLVSIKKNGNHVANSP 116
>AB208865-1|BAD92102.1| 1342|Homo sapiens gamma filamin variant
protein.
Length = 1342
Score = 45.2 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H++ + D IP SP V +++ V ++HG V KP TF + T
Sbjct: 443 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTK 502
Query: 192 AAGPGNLEVTVNG 230
AG G L + V G
Sbjct: 503 DAGEGGLSLAVEG 515
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 891 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 919
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVKDVAH--------GTVGKPVTFL 179
F+P G H ++V + IP SPF ++V + S + GT G F+
Sbjct: 1085 FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFI 1144
Query: 180 VETMAAGPGNLEVTVNG 230
V T+ AG G L VT++G
Sbjct: 1145 VNTLNAGSGALSVTIDG 1161
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Frame = +3
Query: 6 AAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGK 164
+A+ FVP+ +G H + V +P SPF V + A +V+ + G G
Sbjct: 889 SAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGV 948
Query: 165 PVTFLVETMAAGPGNLEVTVNG 230
P F + T AG G L + V G
Sbjct: 949 PAEFSIWTREAGAGGLSIAVEG 970
Score = 39.5 bits (88), Expect = 0.009
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
+ I F P + H+++++FNG H+PGSPF V
Sbjct: 1081 HTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRV 1113
Score = 38.7 bits (86), Expect = 0.015
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHL-----KVYDVSAIRV--KDVAHGTVGKPVTFLV 182
F P+ VGEH ++V + SPF + ++ D S +RV K ++ G + F+V
Sbjct: 622 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIV 681
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G L +++ G
Sbjct: 682 DTRNAGYGGLGLSIEG 697
Score = 38.3 bits (85), Expect = 0.020
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +3
Query: 21 EFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD-VSAIRVKDVAHG-----TVGKPVTFLV 182
E++P G++ +N+ PIP SPF + V D V +VK G P TF V
Sbjct: 25 EYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTV 84
Query: 183 ETMAAGPGNLEVTVNGGRVPTAAA 254
+ AG L+V V G PT A
Sbjct: 85 DCSQAGRAPLQVAVLG---PTGVA 105
Score = 37.1 bits (82), Expect = 0.047
Identities = 15/57 (26%), Positives = 29/57 (50%)
Frame = +2
Query: 218 DGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
+G + +C + T +++ P +P + + ++F HVPGSPF V+ R+
Sbjct: 696 EGPSKVDINCEDMEDG-TCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRM 751
Score = 36.3 bits (80), Expect = 0.082
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
T+ I +T +P + + +RF G+H+P SPF HV A
Sbjct: 318 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF--HVLA 351
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +2
Query: 185 DNGRWSWEFRGDGEWRTGTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVC 364
D G +G + C + T +S+ P P +++ +RF+ H+PGSPF
Sbjct: 503 DAGEGGLSLAVEGPSKAEITCKDNKDG-TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 561
Query: 365 HVS 373
++
Sbjct: 562 KIT 564
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA 376
+S+ ++P + V ++FN +H+P SPFV V++
Sbjct: 988 VSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVAS 1020
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSA-PARVIGA-GSGEPPEKVSVGDAY 442
T + + P + H + ++++G+H+PGSP +V A +R + A G G V+ +
Sbjct: 438 TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATF 497
Query: 443 TFSVDSPTSP--HVEVLGPARRPVLCK 517
T + V GP++ + CK
Sbjct: 498 TIVTKDAGEGGLSLAVEGPSKAEITCK 524
Score = 34.7 bits (76), Expect = 0.25
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCH 367
G TY +S+ P +T+ +++ GD +P SPF H
Sbjct: 211 GDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 246
Score = 34.3 bits (75), Expect = 0.33
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSV 454
ISFTP++ H V +R +G HV SPF V P+ IG S + + +TF V
Sbjct: 620 ISFTPKEVGEHVVSVRKSGKHVTNSPFKILV-GPSE-IGDASKVRVWGKGLSEGHTFQV 676
Score = 33.5 bits (73), Expect = 0.58
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSV 430
G T+ + +TP P+TV +++ VP SPF V ++V +G G +
Sbjct: 114 GDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPA 173
Query: 431 GDAYTFSVDSPTSPH----VEVLGPARRP 505
F++D+ + V++L P +P
Sbjct: 174 SLPVEFTIDARDAGEGLLTVQILDPEGKP 202
Score = 30.7 bits (66), Expect = 4.1
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPF---VCHVSAPARVIGAGSGEPPEKVSVGDAYTF 448
+ + P P + V + F G +PGSPF V V P +V +G G V TF
Sbjct: 24 VEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPG-LGAGVRARVPQTF 82
Query: 449 SVD---SPTSP-HVEVLGP 493
+VD + +P V VLGP
Sbjct: 83 TVDCSQAGRAPLQVAVLGP 101
>AF238609-1|AAF97046.1| 672|Homo sapiens filamen B protein.
Length = 672
Score = 44.8 bits (101), Expect = 2e-04
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPAR 385
YA+ F P + HT++++FNG HV GSPF V P +
Sbjct: 413 YAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQ 450
Score = 39.9 bits (89), Expect = 0.007
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Frame = +3
Query: 3 PAAFRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYD---------VSAIRVKDVAHGT 155
P + F+P G H ++V + + SPF ++V + VSA + GT
Sbjct: 410 PDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT-GLEGGT 468
Query: 156 VGKPVTFLVETMAAGPGNLEVTVNG 230
G F + T AGPG L VT+ G
Sbjct: 469 TGIQSEFFINTTRAGPGTLSVTIEG 493
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 126 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 165
Score = 37.1 bits (82), Expect = 0.047
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV + + G HV GSPF
Sbjct: 219 GKNSHCVRFVPQEMGVHTVSVNYRGQHVTGSPF 251
Score = 35.5 bits (78), Expect = 0.14
Identities = 12/35 (34%), Positives = 24/35 (68%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPA 382
+S+ ++P + V ++FN +H+P SP++ V AP+
Sbjct: 320 VSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS 354
Score = 33.9 bits (74), Expect = 0.44
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDV---SAIRVK----DVAHGTVGKPVTFLV 182
FVP+ +G H ++V + SPF V + A +V+ + G G P F +
Sbjct: 227 FVPQEMGVHTVSVNYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSI 286
Query: 183 ETMAAGPGNLEVTVNG 230
T AG G L + V G
Sbjct: 287 WTREAGAGGLSIAVEG 302
Score = 32.3 bits (70), Expect = 1.3
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVY-----DVSAIRV--KDVAHGTVGKPVTFLV 182
F+PR VGEH +++ + + SP + V D +V + ++ G + F+V
Sbjct: 36 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIV 95
Query: 183 ETMAAGPGNLEVTVNG 230
+T AG G + + V G
Sbjct: 96 DTRDAGYGGISLAVEG 111
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 278 ISFTPRDPRPHTVELRFNGDHVPGSP 355
ISF PR+ H V ++ NG+HV SP
Sbjct: 34 ISFIPREVGEHLVSIKKNGNHVANSP 59
Score = 30.7 bits (66), Expect = 4.1
Identities = 11/40 (27%), Positives = 24/40 (60%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAP 379
G Y +++ ++ + + +++ +H+PGSPF HV+ P
Sbjct: 635 GNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF--HVTVP 672
>BX664723-5|CAI43201.1| 231|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 231
Score = 44.4 bits (100), Expect = 3e-04
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
Frame = +3
Query: 24 FVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVSAIRVK----DVAHGTVGKPVTFLVETM 191
+ P G H +++ D++ IP SP V V+ V + HG V KP TF V T
Sbjct: 114 YAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTK 173
Query: 192 AAGPGNLEVTVNGGRVPTAA 251
AG G+ + ++ +V +AA
Sbjct: 174 DAGEGDDSMRMSHLKVGSAA 193
Score = 30.7 bits (66), Expect = 4.1
Identities = 10/34 (29%), Positives = 20/34 (58%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
T + + P + H +++R++ H+PGSP +V
Sbjct: 109 TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 142
>AJ132990-1|CAB51535.1| 180|Homo sapiens ABP-L, gamma filamin
protein.
Length = 180
Score = 44.0 bits (99), Expect = 4e-04
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 272 YAISFTPRDPRPHTVELRFNGDHVPGSPF 358
Y++ F P++ PHTV +++ G HVPGSPF
Sbjct: 148 YSVRFVPQEMGPHTVAVKYRGQHVPGSPF 176
>AF353667-2|AAL68443.1| 92|Homo sapiens filamin B variant 1
protein.
Length = 92
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 56 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 88
>AF353667-1|AAL68442.1| 133|Homo sapiens filamin B protein.
Length = 133
Score = 37.9 bits (84), Expect = 0.027
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G +++ + F P++ HTV +++ G HV GSPF
Sbjct: 97 GKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 129
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 4 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 43
>AF353667-4|AAL68440.1| 94|Homo sapiens filamin B variant 2
protein.
Length = 94
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 4 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 43
>AF353667-3|AAL68441.1| 98|Homo sapiens filamin B variant 3
protein.
Length = 98
Score = 37.1 bits (82), Expect = 0.047
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARV 388
T +S+ P P + V +F +HVPGSPF +S RV
Sbjct: 4 TCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRV 43
>X70083-1|CAA49688.1| 231|Homo sapiens filamin protein.
Length = 231
Score = 36.3 bits (80), Expect = 0.082
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKVSV-GD 436
G T+ S+ P P HT+ + + G +VP SPF +V G G PE+V V G
Sbjct: 138 GNGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNV---------GEGSHPERVKVYGP 188
Query: 437 AYTFSVDSPTSP 472
+ P SP
Sbjct: 189 GVEKTASRPMSP 200
Score = 33.1 bits (72), Expect = 0.76
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Frame = +3
Query: 12 FRAEFVPRAVGEHRLNVLIDSVPIPASPFHLKVYDVS-AIRVKDVAHG---TVGKPV--- 170
FR +VP +H + + V +P SPF + V + S RVK G T +P+
Sbjct: 142 FRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTASRPMSPP 201
Query: 171 TFLVETMAAGPGNLEVTV 224
TF V+ AG G++ + +
Sbjct: 202 TFTVDCSEAGQGDVSIGI 219
>BC034943-1|AAH34943.1| 562|Homo sapiens TRIM45 protein protein.
Length = 562
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 446 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVTV 479
>AY669488-1|AAT76864.1| 580|Homo sapiens tripartite
motif-containing 45 protein.
Length = 580
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 464 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVTV 497
>AL391476-4|CAI12735.1| 523|Homo sapiens tripartite
motif-containing 45 protein.
Length = 523
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 407 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMV 440
>AL391476-3|CAI12733.1| 580|Homo sapiens tripartite
motif-containing 45 protein.
Length = 580
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 464 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMV 497
>AL391476-2|CAI12734.1| 562|Homo sapiens tripartite
motif-containing 45 protein.
Length = 562
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 446 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMV 479
>AK222901-1|BAD96621.1| 580|Homo sapiens tripartite
motif-containing 45 variant protein.
Length = 580
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 464 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVTV 497
>AK023243-1|BAB14484.1| 580|Homo sapiens protein ( Homo sapiens
cDNA FLJ13181 fis, clone NT2RP3004016, weakly similar to
TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA. ).
Length = 580
Score = 35.9 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHV 370
TY IS+TP++P +TV + HV GSPF V
Sbjct: 464 TYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVTV 497
>X70082-1|CAA49687.1| 115|Homo sapiens filamin protein.
Length = 115
Score = 33.9 bits (74), Expect = 0.44
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
T+ I +T P + + +RF G+HVP SPF
Sbjct: 50 TFDIFYTAPQPGKYVICVRFGGEHVPNSPF 79
>BC041179-1|AAH41179.1| 177|Homo sapiens Similar to filamin C,
gamma (actin binding protein 280) protein.
Length = 177
Score = 33.5 bits (73), Expect = 0.58
Identities = 10/33 (30%), Positives = 23/33 (69%)
Frame = +2
Query: 260 GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
G+ Y++S+ +D +T+ +++ +H+PGSP+
Sbjct: 140 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 172
>BC064361-1|AAH64361.1| 1056|Homo sapiens pleckstrin homology domain
containing, family M (with RUN domain) member 1 protein.
Length = 1056
Score = 32.3 bits (70), Expect = 1.3
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Frame = +2
Query: 248 SGTQ-GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKV 424
SGTQ G H PR P ++L+ + G VS AR +G G+G +
Sbjct: 365 SGTQDGVHVQE----PRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQA 420
Query: 425 SVGDAYTFSVDSPTSP 472
G V SPTSP
Sbjct: 421 HDGAGLKLVVSSPTSP 436
>AJ002220-1|CAB91652.1| 926|Homo sapiens protein ( Homo sapiens B2
gene partial cDNA, clone B2E. ).
Length = 926
Score = 32.3 bits (70), Expect = 1.3
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Frame = +2
Query: 248 SGTQ-GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKV 424
SGTQ G H PR P ++L+ + G VS AR +G G+G +
Sbjct: 235 SGTQDGVHVQE----PRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQA 290
Query: 425 SVGDAYTFSVDSPTSP 472
G V SPTSP
Sbjct: 291 HDGAGLKLVVSSPTSP 306
>AB002354-1|BAA20813.2| 1058|Homo sapiens KIAA0356 protein protein.
Length = 1058
Score = 32.3 bits (70), Expect = 1.3
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Frame = +2
Query: 248 SGTQ-GAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAGSGEPPEKV 424
SGTQ G H PR P ++L+ + G VS AR +G G+G +
Sbjct: 367 SGTQDGVHVQE----PRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQA 422
Query: 425 SVGDAYTFSVDSPTSP 472
G V SPTSP
Sbjct: 423 HDGAGLKLVVSSPTSP 438
>AK096804-1|BAC04866.1| 212|Homo sapiens protein ( Homo sapiens
cDNA FLJ39485 fis, clone PROST2015124. ).
Length = 212
Score = 31.5 bits (68), Expect = 2.3
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Frame = +2
Query: 302 RPHTVELRFNGDHVPGSP----FVCHVSAPARVIGAGSGEPPEKVSVG 433
+P T E R H+PGSP + C VS A +G GS P S G
Sbjct: 5 KPGTAERRRPSRHLPGSPWRPRWACSVSWAASALGVGSSGAPAVRSRG 52
>DQ232881-1|ABB18374.1| 868|Homo sapiens LIN41 protein.
Length = 868
Score = 31.1 bits (67), Expect = 3.1
Identities = 16/55 (29%), Positives = 24/55 (43%)
Frame = +2
Query: 236 GTDCSGTQGAHTYAISFTPRDPRPHTVELRFNGDHVPGSPFVCHVSAPARVIGAG 400
G + S Q TY +S+ P+ H V + H+ SPF V + +G G
Sbjct: 537 GAEVSDQQNG-TYVVSYRPQLEGEHLVSVTLCNQHIENSPFKVVVKSGRSYVGIG 590
>AY481572-1|AAS49899.1| 2240|Homo sapiens death
inducer-obliterator-3 protein.
Length = 2240
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 582 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 641
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 642 VVPSVPMAS 650
>AY481571-1|AAS49898.1| 1189|Homo sapiens death
inducer-obliterator-2 protein.
Length = 1189
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 582 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 641
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 642 VVPSVPMAS 650
>AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/51 (35%), Positives = 21/51 (41%)
Frame = -3
Query: 352 TARHVIAVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRPPFTVTSKFPG 200
TAR A + V PR P V+ AA RPP T S+ PG
Sbjct: 1270 TARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPG 1320
>AL117379-2|CAM28273.1| 1189|Homo sapiens death inducer-obliterator
1 protein.
Length = 1189
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 582 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 641
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 642 VVPSVPMAS 650
>AL117379-1|CAO03650.1| 2240|Homo sapiens death inducer-obliterator
1 protein.
Length = 2240
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 582 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 641
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 642 VVPSVPMAS 650
>AL035669-2|CAI95770.2| 1189|Homo sapiens death inducer-obliterator
1 protein.
Length = 1189
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 582 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 641
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 642 VVPSVPMAS 650
>AL035669-1|CAI95769.2| 2240|Homo sapiens death inducer-obliterator
1 protein.
Length = 2240
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 582 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 641
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 642 VVPSVPMAS 650
>AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marker 4
protein.
Length = 2063
Score = 31.1 bits (67), Expect = 3.1
Identities = 19/61 (31%), Positives = 25/61 (40%)
Frame = +2
Query: 344 PGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEVLGPARRPVLCKYL 523
P S V H S PA + EPP V A + PT H + P+ V +Y+
Sbjct: 952 PSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYM 1011
Query: 524 L 526
L
Sbjct: 1012 L 1012
>AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein.
Length = 2026
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/51 (35%), Positives = 21/51 (41%)
Frame = -3
Query: 352 TARHVIAVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRPPFTVTSKFPG 200
TAR A + V PR P V+ AA RPP T S+ PG
Sbjct: 1251 TARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPG 1301
>AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 31.1 bits (67), Expect = 3.1
Identities = 18/51 (35%), Positives = 21/51 (41%)
Frame = -3
Query: 352 TARHVIAVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRPPFTVTSKFPG 200
TAR A + V PR P V+ AA RPP T S+ PG
Sbjct: 1270 TARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPG 1320
>AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein.
Length = 1609
Score = 31.1 bits (67), Expect = 3.1
Identities = 19/61 (31%), Positives = 25/61 (40%)
Frame = +2
Query: 344 PGSPFVCHVSAPARVIGAGSGEPPEKVSVGDAYTFSVDSPTSPHVEVLGPARRPVLCKYL 523
P S V H S PA + EPP V A + PT H + P+ V +Y+
Sbjct: 498 PSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYM 557
Query: 524 L 526
L
Sbjct: 558 L 558
>AB002331-1|BAA20791.2| 1223|Homo sapiens KIAA0333 protein.
Length = 1223
Score = 31.1 bits (67), Expect = 3.1
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 334 AVETQLNGVRPRIPRREADGVCVSSLRAAAVGTRP-PFTVTS---KFPGPAAIVSTKKVT 167
A++ +G + IP+R SS +AA P P T+ KFPG AA+V +
Sbjct: 616 AIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKP 675
Query: 166 GLPTVPCAT 140
+P+VP A+
Sbjct: 676 VVPSVPMAS 684
>AC002310-2|AAC31672.1| 1223|Homo sapiens leukocyte
function-associated molecule-1 alpha subunit protein.
Length = 1223
Score = 30.3 bits (65), Expect = 5.4
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDH-----VPGSPFVCHVSAPA-RVIGAGSGEPPEKVSV 430
T +SFTP+ P+ H V+ + G H +C + A +GA GE P V
Sbjct: 934 TLYVSFTPKGPKIHQVKHMYQGVHGLVEMQTSKQILCRPAGDAEHTVGAQEGELPCPWGV 993
Query: 431 GDAY 442
+A+
Sbjct: 994 SEAF 997
>Z34282-1|CAA84036.1| 98|Homo sapiens mucin protein.
Length = 98
Score = 29.9 bits (64), Expect = 7.1
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Frame = -1
Query: 507 TGLLAGPSTSTCGDVGESTLNVYASPTDTFSGGSPDPAPITRAG---ADT*HTNGLPGT* 337
T + + P+TST ST + A+ T SG P+P+ A A T T PGT
Sbjct: 12 TSITSAPTTSTNSAPISSTTS--ATTTSRISGPETTPSPVPTASTTSASTTSTTSGPGTT 69
Query: 336 -SPLKRSSTV 310
SP+ +ST+
Sbjct: 70 PSPVPTTSTI 79
>BC146788-1|AAI46789.1| 1761|Homo sapiens jumonji domain containing 1B
protein.
Length = 1761
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 1152 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 1198
>BC117693-1|AAI17694.1| 1551|Homo sapiens JMJD1B protein protein.
Length = 1551
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 942 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 988
>BC001202-1|AAH01202.1| 759|Homo sapiens JMJD1B protein protein.
Length = 759
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 150 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 196
>BC000539-1|AAH00539.2| 1578|Homo sapiens JMJD1B protein protein.
Length = 1578
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 969 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 1015
>AF338242-1|AAK13499.1| 1761|Homo sapiens nuclear protein 5qNCA
protein.
Length = 1761
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 1152 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 1198
>AF251039-1|AAF63765.1| 1417|Homo sapiens putative zinc finger
protein protein.
Length = 1417
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 808 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 854
>AB029005-1|BAA83034.2| 1787|Homo sapiens KIAA1082 protein protein.
Length = 1787
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/48 (37%), Positives = 21/48 (43%)
Frame = +3
Query: 192 AAGPGNLEVTVNGGRVPTAAARKELTHTPSASRRGIRGLTPLSCVSTA 335
+A GN E T +GG P E H P A IR PL S+A
Sbjct: 1178 SASSGN-ETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSA 1224
>Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein.
Length = 3570
Score = 29.5 bits (63), Expect = 9.4
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Frame = -3
Query: 223 TVTSK----FPGPAAIVSTKKVTGLPTVPCATSLTLIADTSYTFRWKGLAGMGTESISTL 56
TVTS F P + + T P ATS T I +S W L+ T ++T+
Sbjct: 622 TVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS-QTTTPMATM 680
Query: 55 SLCSPTA 35
S +P++
Sbjct: 681 STATPSS 687
Score = 29.5 bits (63), Expect = 9.4
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Frame = -3
Query: 223 TVTSK----FPGPAAIVSTKKVTGLPTVPCATSLTLIADTSYTFRWKGLAGMGTESISTL 56
TVTS F P + + T P ATS T I +S W L+ T ++T+
Sbjct: 2378 TVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS-QTTTPMATM 2436
Query: 55 SLCSPTA 35
S +P++
Sbjct: 2437 STATPSS 2443
>X70085-1|CAA49690.1| 71|Homo sapiens filamin protein.
Length = 71
Score = 29.5 bits (63), Expect = 9.4
Identities = 9/30 (30%), Positives = 19/30 (63%)
Frame = +2
Query: 269 TYAISFTPRDPRPHTVELRFNGDHVPGSPF 358
TY +++ P +T+ +++ GD +P SP+
Sbjct: 18 TYTVAYVPDVTGRYTILIKYGGDEIPFSPY 47
>BC033217-1|AAH33217.1| 611|Homo sapiens SARDH protein protein.
Length = 611
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 85 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 114
>AL590710-3|CAI12276.1| 918|Homo sapiens sarcosine dehydrogenase
protein.
Length = 918
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AL590710-2|CAI12275.1| 609|Homo sapiens sarcosine dehydrogenase
protein.
Length = 609
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AL365494-4|CAI13356.1| 918|Homo sapiens sarcosine dehydrogenase
protein.
Length = 918
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AK223402-1|BAD97122.1| 918|Homo sapiens sarcosine dehydrogenase
variant protein.
Length = 918
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AJ298319-1|CAC83676.1| 372|Homo sapiens mucin 5 protein.
Length = 372
Score = 29.5 bits (63), Expect = 9.4
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Frame = -1
Query: 495 AGPSTSTCGDVGESTLNVYASPTDTFSGGSPDPAPIT-RAGADT*HTNGLPG-T*SPLKR 322
+GP TS ST + + T + G +P P P T A T T PG T SP+
Sbjct: 118 SGPGTSLSPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTSAPTTSTTSGPGTTPSPVPT 177
Query: 321 SST 313
+ST
Sbjct: 178 TST 180
>AJ223317-1|CAA11257.1| 475|Homo sapiens sarcosine dehydrogenase
protein.
Length = 475
Score = 29.5 bits (63), Expect = 9.4
Identities = 12/28 (42%), Positives = 17/28 (60%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVI 335
+RR S TDH RW R +HE A+ ++
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAQELL 469
>AF162428-1|AAD43585.1| 918|Homo sapiens sarcosine dehydrogenase
protein.
Length = 918
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AF140745-1|AAD32214.1| 918|Homo sapiens sarcosine dehydrogenase
protein.
Length = 918
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AF129265-1|AAD33412.1| 602|Homo sapiens unknown protein.
Length = 602
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 162 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 191
>AF095735-1|AAD53398.2| 918|Homo sapiens sarcosine dehydrogenase
protein.
Length = 918
Score = 29.5 bits (63), Expect = 9.4
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVIAV 329
+RR S TDH RW R +HE A++ V
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAKNYSVV 471
>AF047190-1|AAD13137.1| 475|Homo sapiens dimethylglycine
dehydrogenase-like protein isoform 2 protein.
Length = 475
Score = 29.5 bits (63), Expect = 9.4
Identities = 12/28 (42%), Positives = 17/28 (60%)
Frame = -3
Query: 418 LRRLARSCTDHARWRRHVTHEWTARHVI 335
+RR S TDH RW R +HE A+ ++
Sbjct: 442 IRRFHHSLTDHPRWIRERSHESYAQELL 469
>AB209544-1|BAD92781.1| 321|Homo sapiens PHD finger protein 13
variant protein.
Length = 321
Score = 29.5 bits (63), Expect = 9.4
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Frame = -1
Query: 405 PDPAPITRAGADT*HTNGLPGT*SP-LKRSSTV*GLGSRGVKLMAYV*APCVPLQSVPVR 229
P P P +D+ P SP KR TV ++AY P + +P+R
Sbjct: 14 PPPPPARNMDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLR 73
Query: 228 HSPSPLNS 205
SPSP NS
Sbjct: 74 SSPSPANS 81
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,463,255
Number of Sequences: 237096
Number of extensions: 2347133
Number of successful extensions: 11629
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 9959
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11552
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6268037466
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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