Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--0602
(621 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37359-1|AAC78721.1| 680|Homo sapiens MRE11 homologue hMre11 pr... 105 2e-22
BT006730-1|AAP35376.1| 206|Homo sapiens MRE11 meiotic recombina... 105 2e-22
BC063458-1|AAH63458.1| 708|Homo sapiens MRE11 meiotic recombina... 105 2e-22
BC017823-1|AAH17823.1| 517|Homo sapiens Unknown (protein for IM... 105 2e-22
BC005241-1|AAH05241.1| 206|Homo sapiens MRE11A protein protein. 105 2e-22
AY584241-1|AAS79320.1| 708|Homo sapiens MRE11 meiotic recombina... 105 2e-22
AF303395-1|AAK18790.1| 708|Homo sapiens meiotic recombination 1... 105 2e-22
AF073362-1|AAC36249.1| 708|Homo sapiens endo/exonuclease Mre11 ... 105 2e-22
AF022778-1|AAD10197.1| 708|Homo sapiens DNA recombination and r... 105 2e-22
J04088-1|AAA61209.1| 1531|Homo sapiens TOP2A protein. 31 3.3
AJ011741-1|CAA09762.1| 1531|Homo sapiens topoisomerase II alpha ... 31 3.3
AF071747-1|AAC77388.1| 1531|Homo sapiens topoisomerase II alpha ... 31 3.3
U42408-1|AAB58817.1| 517|Homo sapiens ladinin protein. 30 5.7
BC071890-1|AAH71890.1| 517|Homo sapiens ladinin 1 protein. 30 5.7
BC009742-1|AAH09742.1| 517|Homo sapiens ladinin 1 protein. 30 5.7
>U37359-1|AAC78721.1| 680|Homo sapiens MRE11 homologue hMre11
protein.
Length = 680
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 69.7 bits (163), Expect = 8e-12
Identities = 30/55 (54%), Positives = 41/55 (74%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D RG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAARGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>BT006730-1|AAP35376.1| 206|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 206
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>BC063458-1|AAH63458.1| 708|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 708
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>BC017823-1|AAH17823.1| 517|Homo sapiens Unknown (protein for
IMAGE:4687479) protein.
Length = 517
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>BC005241-1|AAH05241.1| 206|Homo sapiens MRE11A protein protein.
Length = 206
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>AY584241-1|AAS79320.1| 708|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 708
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>AF303395-1|AAK18790.1| 708|Homo sapiens meiotic recombination 11
protein.
Length = 708
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>AF073362-1|AAC36249.1| 708|Homo sapiens endo/exonuclease Mre11
protein.
Length = 708
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>AF022778-1|AAD10197.1| 708|Homo sapiens DNA recombination and
repair protein protein.
Length = 708
Score = 105 bits (251), Expect = 2e-22
Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 LFDQAKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISY 421
LF + KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS
Sbjct: 61 LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI 120
Query: 422 PILSIHGNHDDPVGQGSVSSLDILSITGLL 511
P+ SIHGNHDDP G ++ +LDILS G +
Sbjct: 121 PVFSIHGNHDDPTGADALCALDILSCAGFV 150
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +3
Query: 90 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGD 254
A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGD
Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD 60
Score = 36.3 bits (80), Expect = 0.087
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 508 INYFGKWTDYTHVRISPVLLQKGLTRLASMDLAILKDQ 621
+N+FG+ + ISPVLLQKG T++A L + D+
Sbjct: 150 VNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDE 187
>J04088-1|AAA61209.1| 1531|Homo sapiens TOP2A protein.
Length = 1531
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = -3
Query: 121 NILSVSSGDHAEMSFSIIILLVQLDYDVISNNLNTIMPIG 2
++ +SS H EMS + I+ + ++ V SNNLN + PIG
Sbjct: 750 SVAEMSSYHHGEMSLMMTIINLAQNF-VGSNNLNLLQPIG 788
>AJ011741-1|CAA09762.1| 1531|Homo sapiens topoisomerase II alpha
protein.
Length = 1531
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = -3
Query: 121 NILSVSSGDHAEMSFSIIILLVQLDYDVISNNLNTIMPIG 2
++ +SS H EMS + I+ + ++ V SNNLN + PIG
Sbjct: 750 SVAEMSSYHHGEMSLMMTIINLAQNF-VGSNNLNLLQPIG 788
>AF071747-1|AAC77388.1| 1531|Homo sapiens topoisomerase II alpha
protein.
Length = 1531
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/40 (40%), Positives = 25/40 (62%)
Frame = -3
Query: 121 NILSVSSGDHAEMSFSIIILLVQLDYDVISNNLNTIMPIG 2
++ +SS H EMS + I+ + ++ V SNNLN + PIG
Sbjct: 750 SVAEMSSYHHGEMSLMMTIINLAQNF-VGSNNLNLLQPIG 788
>U42408-1|AAB58817.1| 517|Homo sapiens ladinin protein.
Length = 517
Score = 30.3 bits (65), Expect = 5.7
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = -3
Query: 247 PKSIKSTSHCTARDKTSSKAIKLSSPRTGSFSMKPR 140
P + + +T S ++K SSPRT SF MKP+
Sbjct: 346 PSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPK 381
>BC071890-1|AAH71890.1| 517|Homo sapiens ladinin 1 protein.
Length = 517
Score = 30.3 bits (65), Expect = 5.7
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = -3
Query: 247 PKSIKSTSHCTARDKTSSKAIKLSSPRTGSFSMKPR 140
P + + +T S ++K SSPRT SF MKP+
Sbjct: 346 PSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPK 381
>BC009742-1|AAH09742.1| 517|Homo sapiens ladinin 1 protein.
Length = 517
Score = 30.3 bits (65), Expect = 5.7
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = -3
Query: 247 PKSIKSTSHCTARDKTSSKAIKLSSPRTGSFSMKPR 140
P + + +T S ++K SSPRT SF MKP+
Sbjct: 346 PSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPK 381
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,426,846
Number of Sequences: 237096
Number of extensions: 1726129
Number of successful extensions: 7090
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6965
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7081
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6691573490
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -