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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ce--0492
         (415 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1; ...   126   1e-28
UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1...   126   1e-28
UniRef50_UPI0000F33279 Cluster: Cullin 1; n=1; Bos taurus|Rep: C...   120   2e-26
UniRef50_Q4PFM6 Cluster: Putative uncharacterized protein; n=2; ...   102   3e-21
UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep: Cull...   100   1e-20
UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2...    97   1e-19
UniRef50_Q9XZJ3 Cluster: CulB; n=2; Dictyostelium discoideum|Rep...    92   4e-18
UniRef50_A6RRX7 Cluster: Putative uncharacterized protein; n=1; ...    91   1e-17
UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces pomb...    91   1e-17
UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cul...    89   4e-17
UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1; ...    88   6e-17
UniRef50_Q4SKR4 Cluster: Chromosome undetermined SCAF14565, whol...    87   1e-16
UniRef50_Q13617 Cluster: Cullin-2; n=21; Tetrapoda|Rep: Cullin-2...    86   3e-16
UniRef50_A6RFP0 Cluster: Putative uncharacterized protein; n=1; ...    85   4e-16
UniRef50_A2QRF8 Cluster: Contig An08c0130, complete genome; n=15...    85   7e-16
UniRef50_Q54NZ5 Cluster: Putative uncharacterized protein; n=1; ...    83   2e-15
UniRef50_Q7SG66 Cluster: Putative uncharacterized protein NCU024...    83   2e-15
UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin ...    83   3e-15
UniRef50_Q4P2V0 Cluster: Putative uncharacterized protein; n=1; ...    81   7e-15
UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|R...    81   7e-15
UniRef50_Q17390 Cluster: Cullin-2; n=6; Caenorhabditis|Rep: Cull...    81   9e-15
UniRef50_Q9U4X7 Cluster: Cullin-like protein; n=1; Strongyloides...    80   2e-14
UniRef50_Q5D9F0 Cluster: SJCHGC09488 protein; n=1; Schistosoma j...    79   5e-14
UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces cere...    77   1e-13
UniRef50_Q6CFU9 Cluster: Similar to sp|Q09760 Schizosaccharomyce...    77   1e-13
UniRef50_Q5KDB7 Cluster: Ubiquitin-protein ligase, putative; n=2...    77   1e-13
UniRef50_A1CTB7 Cluster: SCF ubiquitin ligase subunit CulC, puta...    76   3e-13
UniRef50_A2YRN6 Cluster: Putative uncharacterized protein; n=1; ...    75   4e-13
UniRef50_A3GH14 Cluster: Predicted protein; n=3; Saccharomycetal...    75   8e-13
UniRef50_Q13618 Cluster: Cullin-3; n=61; Eumetazoa|Rep: Cullin-3...    73   2e-12
UniRef50_Q17391 Cluster: Cullin-3; n=2; Caenorhabditis|Rep: Cull...    73   2e-12
UniRef50_A6S1H5 Cluster: Putative uncharacterized protein; n=2; ...    72   4e-12
UniRef50_Q94AH6 Cluster: Cullin-1; n=13; Magnoliophyta|Rep: Cull...    71   7e-12
UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involv...    71   9e-12
UniRef50_A5DRN9 Cluster: Putative uncharacterized protein; n=1; ...    71   1e-11
UniRef50_Q9ZVH4 Cluster: T2P11.2 protein; n=18; Magnoliophyta|Re...    70   2e-11
UniRef50_UPI0000364D21 Cluster: Cullin-3 (CUL-3).; n=1; Takifugu...    69   5e-11
UniRef50_Q237B9 Cluster: Cullin family protein; n=1; Tetrahymena...    69   5e-11
UniRef50_Q6BUD8 Cluster: Similar to CA5841|IPF420 Candida albica...    69   5e-11
UniRef50_UPI00005A31AC Cluster: PREDICTED: similar to Cullin-3 (...    66   2e-10
UniRef50_A4RUG3 Cluster: Predicted protein; n=2; Ostreococcus|Re...    66   2e-10
UniRef50_Q4QAA1 Cluster: Cullin-like protein-like protein; n=3; ...    66   3e-10
UniRef50_Q10CD7 Cluster: Cullin-4B, putative, expressed; n=8; Vi...    66   4e-10
UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1; ...    66   4e-10
UniRef50_UPI000049970B Cluster: cullin; n=1; Entamoeba histolyti...    65   6e-10
UniRef50_A6S251 Cluster: Putative uncharacterized protein; n=1; ...    65   6e-10
UniRef50_Q01BJ3 Cluster: Putative cullin; n=1; Ostreococcus taur...    64   8e-10
UniRef50_UPI0000499E7A Cluster: cullin; n=1; Entamoeba histolyti...    63   2e-09
UniRef50_A0CT81 Cluster: Chromosome undetermined scaffold_27, wh...    63   3e-09
UniRef50_A6QYU9 Cluster: Putative uncharacterized protein; n=1; ...    63   3e-09
UniRef50_Q13620 Cluster: Cullin-4B; n=95; Eukaryota|Rep: Cullin-...    62   3e-09
UniRef50_A0CBV9 Cluster: Chromosome undetermined scaffold_165, w...    62   4e-09
UniRef50_Q5KDE6 Cluster: Ubiquitin-protein ligase, putative; n=1...    62   4e-09
UniRef50_Q1DK65 Cluster: Putative uncharacterized protein; n=1; ...    62   6e-09
UniRef50_Q4RTC1 Cluster: Chromosome 1 SCAF14998, whole genome sh...    61   8e-09
UniRef50_Q17392 Cluster: Cullin-4; n=2; Caenorhabditis|Rep: Cull...    61   1e-08
UniRef50_Q015Y9 Cluster: Cullin-like protein1; n=17; Viridiplant...    60   1e-08
UniRef50_A7RI48 Cluster: Predicted protein; n=1; Nematostella ve...    60   1e-08
UniRef50_Q09760 Cluster: Cullin-3; n=1; Schizosaccharomyces pomb...    60   1e-08
UniRef50_Q54CS2 Cluster: Putative uncharacterized protein; n=1; ...    60   2e-08
UniRef50_Q7QJY4 Cluster: ENSANGP00000021534; n=1; Anopheles gamb...    59   3e-08
UniRef50_Q9VU33 Cluster: CG11261-PA; n=1; Drosophila melanogaste...    58   5e-08
UniRef50_Q236I8 Cluster: Cullin family protein; n=1; Tetrahymena...    58   5e-08
UniRef50_Q23CK5 Cluster: Cullin family protein; n=1; Tetrahymena...    58   7e-08
UniRef50_O14122 Cluster: Cullin-4; n=1; Schizosaccharomyces pomb...    58   7e-08
UniRef50_Q7RZU1 Cluster: Putative uncharacterized protein NCU002...    57   1e-07
UniRef50_UPI0000498BA9 Cluster: cullin; n=1; Entamoeba histolyti...    55   7e-07
UniRef50_Q24CG0 Cluster: Cullin family protein; n=1; Tetrahymena...    55   7e-07
UniRef50_A1CBL2 Cluster: Ubiquitin ligase subunit CulD, putative...    54   1e-06
UniRef50_Q5T2B5 Cluster: Cullin 2; n=18; Coelomata|Rep: Cullin 2...    54   2e-06
UniRef50_Q6CI31 Cluster: Similar to sp|O14122 Schizosaccharomyce...    54   2e-06
UniRef50_Q57YJ8 Cluster: Cullin, putative; n=2; Trypanosoma|Rep:...    53   2e-06
UniRef50_Q4CW84 Cluster: Putative uncharacterized protein; n=2; ...    53   2e-06
UniRef50_Q23639 Cluster: Cullin-5; n=2; Caenorhabditis|Rep: Cull...    52   4e-06
UniRef50_UPI0000498B52 Cluster: cullin; n=1; Entamoeba histolyti...    52   5e-06
UniRef50_A0CFE8 Cluster: Chromosome undetermined scaffold_175, w...    52   5e-06
UniRef50_P53202 Cluster: Cullin-3; n=2; Saccharomyces cerevisiae...    51   8e-06
UniRef50_Q4FKJ0 Cluster: Putative uncharacterized protein; n=1; ...    50   1e-05
UniRef50_Q93034 Cluster: Cullin-5; n=38; Eumetazoa|Rep: Cullin-5...    50   2e-05
UniRef50_A5JZR9 Cluster: Cullin, putative; n=4; Plasmodium|Rep: ...    50   2e-05
UniRef50_UPI0000498870 Cluster: hypothetical protein 160.t00020;...    48   6e-05
UniRef50_Q236H3 Cluster: Cullin family protein; n=1; Tetrahymena...    48   6e-05
UniRef50_Q752S5 Cluster: AFR498Wp; n=1; Eremothecium gossypii|Re...    48   6e-05
UniRef50_Q6FTV0 Cluster: Similar to sp|P53202 Saccharomyces cere...    47   1e-04
UniRef50_Q4DVD1 Cluster: Putative uncharacterized protein; n=2; ...    46   2e-04
UniRef50_UPI000150A116 Cluster: Cullin family protein; n=1; Tetr...    46   3e-04
UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein ...    45   5e-04
UniRef50_Q24DT3 Cluster: Cullin family protein; n=1; Tetrahymena...    45   5e-04
UniRef50_UPI0000E47A13 Cluster: PREDICTED: similar to MGC80402 p...    44   0.001
UniRef50_Q4QEP5 Cluster: Putative uncharacterized protein; n=2; ...    44   0.002
UniRef50_A0C548 Cluster: Chromosome undetermined scaffold_15, wh...    44   0.002
UniRef50_Q5CP75 Cluster: Cullin 1 protein-related; n=2; Cryptosp...    42   0.004
UniRef50_Q4Q1I0 Cluster: Putative uncharacterized protein; n=3; ...    41   0.009
UniRef50_A0BLH1 Cluster: Chromosome undetermined scaffold_114, w...    41   0.009
UniRef50_A2FHP4 Cluster: Putative uncharacterized protein; n=1; ...    40   0.027
UniRef50_Q383D5 Cluster: Cullin 1, putative; n=1; Trypanosoma br...    39   0.047
UniRef50_A7TKA1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.081
UniRef50_Q57XW2 Cluster: Cullin 4B, putative; n=1; Trypanosoma b...    36   0.33 
UniRef50_UPI0000D8A8BE Cluster: UPI0000D8A8BE related cluster; n...    36   0.43 
UniRef50_Q4D5L7 Cluster: Cullin 2, putative; n=2; Trypanosoma cr...    36   0.43 
UniRef50_Q5AA44 Cluster: Putative uncharacterized protein RTT101...    34   1.0  
UniRef50_A3GFR1 Cluster: Cullin, ubiquitin ligase activity; n=2;...    34   1.3  
UniRef50_UPI0000498755 Cluster: cullin; n=1; Entamoeba histolyti...    33   3.1  
UniRef50_A0BJA6 Cluster: Chromosome undetermined scaffold_11, wh...    33   3.1  
UniRef50_Q4CRP5 Cluster: Putative uncharacterized protein; n=2; ...    32   4.0  
UniRef50_Q4Q9W5 Cluster: Putative uncharacterized protein; n=3; ...    32   5.3  
UniRef50_A7TQC4 Cluster: Putative uncharacterized protein; n=1; ...    32   5.3  
UniRef50_A7KAI5 Cluster: Atg6p; n=1; Pichia angusta|Rep: Atg6p -...    32   5.3  
UniRef50_Q5CUH7 Cluster: Cullin domain containing protein; n=2; ...    31   7.1  
UniRef50_A2FN39 Cluster: Putative uncharacterized protein; n=1; ...    31   7.1  
UniRef50_A2E3X9 Cluster: Putative uncharacterized protein; n=1; ...    31   7.1  

>UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1; n=2;
            Apocrita|Rep: PREDICTED: similar to cullin 1 - Nasonia
            vitripennis
          Length = 810

 Score =  126 bits (305), Expect = 1e-28
 Identities = 69/106 (65%), Positives = 79/106 (74%), Gaps = 1/106 (0%)
 Frame = -2

Query: 357  YSGYKSKKLRVKYKHTVQDGA*S*PRGYTQTH*G-DRKMLIQSAIVRIM*TRKTLKHQHL 181
            ++GYK+KKLRV     ++       +  T  H   DRK+LIQ+AIVRIM  RK LKHQ L
Sbjct: 706  FTGYKNKKLRVNINIPMKTEL-KIEQETTHKHIEEDRKLLIQAAIVRIMKMRKVLKHQQL 764

Query: 180  VVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
            V EVLNQLS RFKPRV VIKKCID+LIEKEYLERTEG+KDTY YLA
Sbjct: 765  VAEVLNQLSIRFKPRVHVIKKCIDILIEKEYLERTEGQKDTYSYLA 810


>UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1 -
           Homo sapiens (Human)
          Length = 776

 Score =  126 bits (305), Expect = 1e-28
 Identities = 67/105 (63%), Positives = 76/105 (72%)
 Frame = -2

Query: 357 YSGYKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLV 178
           Y GYK+KKLRV     ++           +    DRK+LIQ+AIVRIM  RK LKHQ L+
Sbjct: 672 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLL 731

Query: 177 VEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
            EVL QLSSRFKPRVPVIKKCID+LIEKEYLER +GEKDTY YLA
Sbjct: 732 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776


>UniRef50_UPI0000F33279 Cluster: Cullin 1; n=1; Bos taurus|Rep:
           Cullin 1 - Bos Taurus
          Length = 534

 Score =  120 bits (288), Expect = 2e-26
 Identities = 58/71 (81%), Positives = 63/71 (88%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK+LIQ+AIVRIM  RK LKHQ L+ EVL QLSSRFKPRVPVIKKCID+LIEKEYLER 
Sbjct: 464 DRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERV 523

Query: 75  EGEKDTYRYLA 43
           +GEKDTY YLA
Sbjct: 524 DGEKDTYSYLA 534



 Score = 39.5 bits (88), Expect = 0.027
 Identities = 17/28 (60%), Positives = 20/28 (71%)
 Frame = -3

Query: 323 NINTPFKTELKVDQEATHKHIEETERCL 240
           NIN P KTE K +QE THK+IEE  + L
Sbjct: 441 NINVPMKTEQKQEQETTHKNIEEDRKLL 468


>UniRef50_Q4PFM6 Cluster: Putative uncharacterized protein; n=2;
            Fungi/Metazoa group|Rep: Putative uncharacterized protein
            - Ustilago maydis (Smut fungus)
          Length = 806

 Score =  102 bits (245), Expect = 3e-21
 Identities = 54/104 (51%), Positives = 69/104 (66%)
 Frame = -2

Query: 354  SGYKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVV 175
            + +KSKKLRV     V+    +      +T   DR++L+Q+ IVR+M +RK LKHQ L+ 
Sbjct: 703  ANFKSKKLRVNLNLPVKAEQKAESNDVLKTIDEDRRLLLQATIVRVMKSRKQLKHQALIQ 762

Query: 174  EVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
            E + Q+S RF PRV  IKK ID LI+KEYLER EG KDTY YLA
Sbjct: 763  ETVAQVSGRFNPRVSDIKKAIDQLIDKEYLERLEGSKDTYSYLA 806


>UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep:
           Cullin-1 - Caenorhabditis elegans
          Length = 780

 Score =  100 bits (240), Expect = 1e-20
 Identities = 53/103 (51%), Positives = 69/103 (66%), Gaps = 1/103 (0%)
 Frame = -2

Query: 348 YKSKKLRVKY-KHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVE 172
           Y +KK+RV   K T++  A        +    DRK +I + IVRIM TRK ++HQ L+ E
Sbjct: 678 YMNKKVRVDLSKFTMKQDAVRDTENVQKNVEEDRKSVISACIVRIMKTRKRVQHQQLMTE 737

Query: 171 VLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           V+ QLS RFKP+V +IK+CI  LIEKEY+ RTEG+KD Y YLA
Sbjct: 738 VITQLSGRFKPKVEMIKRCIGSLIEKEYMLRTEGQKDLYEYLA 780


>UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2;
           Filobasidiella neoformans|Rep: Ubiquitin-protein ligase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 775

 Score = 97.1 bits (231), Expect = 1e-19
 Identities = 48/104 (46%), Positives = 68/104 (65%)
 Frame = -2

Query: 354 SGYKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVV 175
           +G+KSKK+RV    T++  A +  +        DRK + Q+ IVR+M  RKT++HQ L+ 
Sbjct: 672 TGFKSKKIRVNLNQTIKSEARAEQKEVIAAVDEDRKFVYQATIVRLMKGRKTMQHQALIQ 731

Query: 174 EVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           EV  Q+SS+F P++P IKK I+ LI+KEYLER     +TY YLA
Sbjct: 732 EVTAQISSKFTPKIPEIKKAIEYLIDKEYLERAPDSNNTYNYLA 775


>UniRef50_Q9XZJ3 Cluster: CulB; n=2; Dictyostelium discoideum|Rep:
           CulB - Dictyostelium discoideum (Slime mold)
          Length = 771

 Score = 92.3 bits (219), Expect = 4e-18
 Identities = 48/107 (44%), Positives = 67/107 (62%), Gaps = 3/107 (2%)
 Frame = -2

Query: 354 SGYKSKKLRVKYKHTVQDGA*S*PRGYTQTH*G---DRKMLIQSAIVRIM*TRKTLKHQH 184
           S Y +K+ +VK   ++Q      P    +T+ G   DRK+ +Q++IVRIM  RKT+ H  
Sbjct: 668 SAYSNKRSKVKVSSSLQKET---PLQNEETYKGIDEDRKLYLQASIVRIMKARKTMNHVS 724

Query: 183 LVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           L+ EV+     RF+P +P+IKKCI+ LIEKEY+ R EGE D Y Y A
Sbjct: 725 LIQEVIEHSRLRFQPNIPMIKKCIEQLIEKEYITRAEGESDRYLYAA 771


>UniRef50_A6RRX7 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 740

 Score = 90.6 bits (215), Expect = 1e-17
 Identities = 47/98 (47%), Positives = 65/98 (66%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           +KSKK+RV     ++           +T   DRK+L+QSAIVRIM  RK +KH  LV E 
Sbjct: 641 FKSKKIRVNLNIAIKSEQKQEVDETHKTIEEDRKLLMQSAIVRIMKARKKMKHSVLVAET 700

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTY 55
           ++Q+ +RF P+VP IKKCID+L+EKEYLER + ++  Y
Sbjct: 701 ISQIRTRFSPKVPDIKKCIDILLEKEYLERLDDDELGY 738


>UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces
           pombe|Rep: Cullin-1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 767

 Score = 90.6 bits (215), Expect = 1e-17
 Identities = 52/102 (50%), Positives = 69/102 (67%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           ++ KK+RV+    ++           +T   DRK+L+QSAIVRIM  R+TLKH  LV E 
Sbjct: 668 FRMKKIRVQLNLPIRSEQKQESLETHKTIEEDRKLLLQSAIVRIMKARRTLKHVVLVKET 727

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           ++Q+ SRF P+V  IK+CIDMLIEKEYLER +G +D Y YLA
Sbjct: 728 IDQIKSRFTPKVSDIKQCIDMLIEKEYLER-QG-RDEYIYLA 767


>UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cullin
           - Oikopleura dioica (Tunicate)
          Length = 770

 Score = 88.6 bits (210), Expect = 4e-17
 Identities = 43/71 (60%), Positives = 54/71 (76%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK+LIQ+AIVRIM TRK + H  L+ E +N L+SRFKP V  IK C++ LIEKEY+ER 
Sbjct: 701 DRKLLIQAAIVRIMKTRKQVNHSTLMSETINHLASRFKPSVQKIKACVETLIEKEYIERV 760

Query: 75  EGEKDTYRYLA 43
           +G KD Y Y+A
Sbjct: 761 DG-KDVYIYVA 770


>UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 724

 Score = 88.2 bits (209), Expect = 6e-17
 Identities = 49/102 (48%), Positives = 66/102 (64%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           +K+KK RV     ++           +T   DRK+L+QSAIVRIM  RK +KHQ LV E 
Sbjct: 625 FKNKKYRVNLNVGMKSETKQEEAETNKTIEEDRKLLLQSAIVRIMKARKHMKHQQLVSEA 684

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           +NQ+ +RF P+V  IKKCI++L++KEYLER   E+D   YLA
Sbjct: 685 INQIRARFVPKVSDIKKCIEILLDKEYLERL--EEDEIGYLA 724


>UniRef50_Q4SKR4 Cluster: Chromosome undetermined SCAF14565, whole
           genome shotgun sequence; n=4; Deuterostomia|Rep:
           Chromosome undetermined SCAF14565, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 855

 Score = 87.4 bits (207), Expect = 1e-16
 Identities = 38/71 (53%), Positives = 54/71 (76%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRKM +Q+AIVRIM  RK L+H  L+ EV+NQ  +RF P + +IKKCI++LI+K+Y+ER+
Sbjct: 785 DRKMYLQAAIVRIMKARKVLRHNALIQEVINQSKARFNPSISMIKKCIEVLIDKQYIERS 844

Query: 75  EGEKDTYRYLA 43
           +   D Y Y+A
Sbjct: 845 QTSADEYSYVA 855


>UniRef50_Q13617 Cluster: Cullin-2; n=21; Tetrapoda|Rep: Cullin-2 -
           Homo sapiens (Human)
          Length = 745

 Score = 85.8 bits (203), Expect = 3e-16
 Identities = 37/71 (52%), Positives = 54/71 (76%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRKM +Q+AIVRIM  RK L+H  L+ EV++Q  +RF P + +IKKCI++LI+K+Y+ER+
Sbjct: 675 DRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERS 734

Query: 75  EGEKDTYRYLA 43
           +   D Y Y+A
Sbjct: 735 QASADEYSYVA 745


>UniRef50_A6RFP0 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 718

 Score = 85.4 bits (202), Expect = 4e-16
 Identities = 45/98 (45%), Positives = 65/98 (66%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           +K+KK+++    +V+           +T   DRK+L+QSAIVRIM +RK LKH  LV EV
Sbjct: 619 FKAKKIKINLNISVKSEQKHETDDTHKTIDEDRKLLLQSAIVRIMKSRKKLKHVQLVQEV 678

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTY 55
           + Q+ +RF P+VP IKK I+ L+EKEY+ER +G+   Y
Sbjct: 679 IQQVKARFPPKVPDIKKNIEALMEKEYIERLDGDDLAY 716


>UniRef50_A2QRF8 Cluster: Contig An08c0130, complete genome; n=15;
           Pezizomycotina|Rep: Contig An08c0130, complete genome -
           Aspergillus niger
          Length = 783

 Score = 84.6 bits (200), Expect = 7e-16
 Identities = 44/98 (44%), Positives = 65/98 (66%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           +K+KK++V     ++           +T   DRK+L+QSAIVRIM +RK +KH  LV EV
Sbjct: 684 FKNKKIKVNLNIQIKSEQKVESDDTHKTIEEDRKLLLQSAIVRIMKSRKKMKHVQLVQEV 743

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTY 55
           + Q+ SRF P+VP IKK I+ L+EK+Y+ER +G++  Y
Sbjct: 744 IQQVKSRFPPKVPDIKKNIEALMEKDYIERLDGDEIAY 781


>UniRef50_Q54NZ5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 769

 Score = 83.4 bits (197), Expect = 2e-15
 Identities = 46/102 (45%), Positives = 63/102 (61%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           +KSK  RVK    VQ       +        DRK  I+++IVRIM  RKTL+H +LV EV
Sbjct: 668 FKSKLFRVKVMAVVQKETPVEEKETRDKVDEDRKHQIEASIVRIMKARKTLEHSNLVSEV 727

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           + QL SRF P   ++KK I+ LIE+EYLER++ ++  Y Y+A
Sbjct: 728 IKQLQSRFVPNPVIVKKRIESLIEREYLERSKQDRKIYNYMA 769


>UniRef50_Q7SG66 Cluster: Putative uncharacterized protein
           NCU02498.1; n=4; Sordariomycetes|Rep: Putative
           uncharacterized protein NCU02498.1 - Neurospora crassa
          Length = 838

 Score = 83.0 bits (196), Expect = 2e-15
 Identities = 41/70 (58%), Positives = 51/70 (72%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R  +I +A+VRIM  RK L H  LV EV++QL  RFKP VP+IKK I+ L+ +EYLER E
Sbjct: 769 RAHVIDAAVVRIMKQRKLLAHTKLVNEVISQLMGRFKPDVPLIKKRIEDLLAREYLERVE 828

Query: 72  GEKDTYRYLA 43
           G+  TYRYLA
Sbjct: 829 GDSSTYRYLA 838


>UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin -
           Aedes aegypti (Yellowfever mosquito)
          Length = 757

 Score = 82.6 bits (195), Expect = 3e-15
 Identities = 40/68 (58%), Positives = 48/68 (70%)
 Frame = -2

Query: 249 KMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEG 70
           + +IQ+AIVRIM   +T+ H  LV EVL QLS   KP+V  IKK ID+LIEKEYLER EG
Sbjct: 689 RFVIQAAIVRIMKQHRTMNHSDLVAEVLKQLSKGLKPKVRAIKKAIDVLIEKEYLERQEG 748

Query: 69  EKDTYRYL 46
             D Y Y+
Sbjct: 749 TVDAYSYM 756


>UniRef50_Q4P2V0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 822

 Score = 81.4 bits (192), Expect = 7e-15
 Identities = 35/71 (49%), Positives = 54/71 (76%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR++++Q+A VR++  +KT+KH  L+ EV++Q+ +RF   V  IKK  ++LIEKEY+ER 
Sbjct: 752 DRELILQAATVRVLKAKKTIKHSELITEVVDQIKNRFTVDVAEIKKEFEILIEKEYMERV 811

Query: 75  EGEKDTYRYLA 43
           EG++  YRYLA
Sbjct: 812 EGQRGMYRYLA 822


>UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|Rep:
           Cullin-6 - Caenorhabditis elegans
          Length = 729

 Score = 81.4 bits (192), Expect = 7e-15
 Identities = 45/103 (43%), Positives = 63/103 (61%), Gaps = 1/103 (0%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQ-TH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVE 172
           Y +KK+RV     ++           Q T   DRK  I++ IVRIM TRK+L H  L+ E
Sbjct: 627 YANKKVRVDLTTAIKKATADRETDAVQNTVESDRKYEIKACIVRIMKTRKSLTHTLLINE 686

Query: 171 VLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           +++QL SRF P V +IK CI++LIE+ Y+ R+E E + Y YLA
Sbjct: 687 IISQLKSRFTPNVQMIKICIEILIEQLYIRRSENEHNVYEYLA 729


>UniRef50_Q17390 Cluster: Cullin-2; n=6; Caenorhabditis|Rep:
           Cullin-2 - Caenorhabditis elegans
          Length = 776

 Score = 81.0 bits (191), Expect = 9e-15
 Identities = 40/71 (56%), Positives = 51/71 (71%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  ++ AIVRIM TRK LKH  LV E+++Q   RF P VP IKK I+ LIEK Y++RT
Sbjct: 707 DRKYYMECAIVRIMKTRKVLKHNALVTEIMDQTKGRFSPDVPFIKKSIEDLIEKMYIQRT 766

Query: 75  EGEKDTYRYLA 43
           + + D Y+YLA
Sbjct: 767 D-QNDEYQYLA 776


>UniRef50_Q9U4X7 Cluster: Cullin-like protein; n=1; Strongyloides
           stercoralis|Rep: Cullin-like protein - Strongyloides
           stercoralis
          Length = 148

 Score = 80.2 bits (189), Expect = 2e-14
 Identities = 36/71 (50%), Positives = 49/71 (69%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I +AIVR+M  RKTL H +L+ EV N L  RF+P +  IKKCI+ LIE+++ +R 
Sbjct: 78  DRKAEIDAAIVRVMKARKTLNHNNLITEVTNVLCKRFRPEILTIKKCIEXLIERDFXKRN 137

Query: 75  EGEKDTYRYLA 43
           E +  TY Y+A
Sbjct: 138 EKDNKTYEYVA 148


>UniRef50_Q5D9F0 Cluster: SJCHGC09488 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC09488 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 221

 Score = 78.6 bits (185), Expect = 5e-14
 Identities = 35/71 (49%), Positives = 50/71 (70%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  IQ+AIVRI+  R+ +KH  L+  +L Q S+RF+P +P+IK+CI+ LI+  YLER 
Sbjct: 151 DRRYFIQAAIVRILKARRQIKHAQLIETILQQASNRFQPPIPLIKRCIEGLIDTGYLERN 210

Query: 75  EGEKDTYRYLA 43
             + D Y YLA
Sbjct: 211 PDDPDQYSYLA 221


>UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces
           cerevisiae YDL132w CDC53 controls G1/S transition; n=1;
           Yarrowia lipolytica|Rep: Similar to sp|Q12018
           Saccharomyces cerevisiae YDL132w CDC53 controls G1/S
           transition - Yarrowia lipolytica (Candida lipolytica)
          Length = 788

 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 44/102 (43%), Positives = 59/102 (57%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           +KSKK+R+     ++  A +      +    DRK  +Q+ IVR+M  RKTLKH  LV E 
Sbjct: 689 FKSKKIRININGVIKTEAKAEAEETKKAIEEDRKWFLQATIVRVMKARKTLKHTALVQET 748

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           + Q   RF P++  IKK ID LIE+EYL R   E+D Y Y A
Sbjct: 749 IVQSKKRFHPKIGEIKKVIDDLIEREYLTRI--EQDKYEYAA 788


>UniRef50_Q6CFU9 Cluster: Similar to sp|Q09760 Schizosaccharomyces
           pombe Cullin 3 homolog; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|Q09760 Schizosaccharomyces pombe Cullin 3
           homolog - Yarrowia lipolytica (Candida lipolytica)
          Length = 778

 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 36/70 (51%), Positives = 49/70 (70%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R+  I +AIVR+M +RKTL H +LV EV  QL+SRFKP +P IK CI+ L+E+EYL R +
Sbjct: 709 RQNEIDAAIVRVMKSRKTLNHNNLVGEVTKQLASRFKPPIPTIKHCIESLLEREYLRRDD 768

Query: 72  GEKDTYRYLA 43
            +   + Y A
Sbjct: 769 NDTTLFHYEA 778


>UniRef50_Q5KDB7 Cluster: Ubiquitin-protein ligase, putative; n=2;
           Filobasidiella neoformans|Rep: Ubiquitin-protein ligase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 808

 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 39/71 (54%), Positives = 53/71 (74%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +RK  +++ IVRIM  RKT++H  LV EV +QL+ RF   VP+IKK I+ LI++EYLERT
Sbjct: 739 ERKHQVEACIVRIMKDRKTMRHNDLVSEVAHQLAKRFMASVPMIKKRIEGLIDREYLERT 798

Query: 75  EGEKDTYRYLA 43
           E +  +YRYLA
Sbjct: 799 E-DMGSYRYLA 808


>UniRef50_A1CTB7 Cluster: SCF ubiquitin ligase subunit CulC,
           putative; n=10; Pezizomycotina|Rep: SCF ubiquitin ligase
           subunit CulC, putative - Aspergillus clavatus
          Length = 857

 Score = 76.2 bits (179), Expect = 3e-13
 Identities = 38/71 (53%), Positives = 51/71 (71%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R   +++A+VRIM  RKTL H  L+ EVL+QLSSRF P V ++KK I+ LI++EYLER 
Sbjct: 787 ERGASVEAAVVRIMKQRKTLVHSSLMSEVLSQLSSRFVPDVNMVKKRIESLIDREYLERV 846

Query: 75  EGEKDTYRYLA 43
             E  TY Y+A
Sbjct: 847 AEEPPTYGYIA 857


>UniRef50_A2YRN6 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 662

 Score = 75.4 bits (177), Expect = 4e-13
 Identities = 37/71 (52%), Positives = 49/71 (69%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I++AIVRIM +R+ L H  +V EV  QL  RF P   VIKK ++ LIE+E+LER 
Sbjct: 592 DRKPQIEAAIVRIMKSRRVLDHNSIVTEVTKQLQPRFMPNPVVIKKRVESLIEREFLERD 651

Query: 75  EGEKDTYRYLA 43
           + ++  YRYLA
Sbjct: 652 KTDRKLYRYLA 662


>UniRef50_A3GH14 Cluster: Predicted protein; n=3;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 736

 Score = 74.5 bits (175), Expect = 8e-13
 Identities = 34/70 (48%), Positives = 53/70 (75%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           RK+ + +AIVRIM +R T++H  L+ E++ QL +RF+P + +IK+ I+ LIEKEYL+R E
Sbjct: 667 RKIEVNAAIVRIMKSRHTIRHNELIEELIKQLQNRFQPLILLIKQRIEDLIEKEYLKRDE 726

Query: 72  GEKDTYRYLA 43
            E++ Y Y+A
Sbjct: 727 EERNLYHYVA 736


>UniRef50_Q13618 Cluster: Cullin-3; n=61; Eumetazoa|Rep: Cullin-3 -
           Homo sapiens (Human)
          Length = 768

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 38/71 (53%), Positives = 49/71 (69%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I++AIVRIM +RK ++H  LV EV  QL +RF P   VIKK I+ LIE+EYL RT
Sbjct: 698 DRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLART 757

Query: 75  EGEKDTYRYLA 43
             ++  Y Y+A
Sbjct: 758 PEDRKVYTYVA 768


>UniRef50_Q17391 Cluster: Cullin-3; n=2; Caenorhabditis|Rep:
           Cullin-3 - Caenorhabditis elegans
          Length = 777

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 36/71 (50%), Positives = 48/71 (67%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK+ +++AIVRIM  RK L H +LV EV  QL  RF P   +IK+ I+ LIE+EYL R 
Sbjct: 707 DRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARD 766

Query: 75  EGEKDTYRYLA 43
           E +   Y+Y+A
Sbjct: 767 EHDHRAYQYIA 777


>UniRef50_A6S1H5 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 850

 Score = 72.1 bits (169), Expect = 4e-12
 Identities = 36/71 (50%), Positives = 50/71 (70%), Gaps = 1/71 (1%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R  ++ + IVRIM  RK   HQ LV EV++QL+ RF+P + ++K+ I+ LIE+EYLER E
Sbjct: 780 RGNVMDTVIVRIMKARKEFPHQQLVTEVISQLAQRFQPNINMMKRRIESLIEREYLERIE 839

Query: 72  GEK-DTYRYLA 43
             K  TY+YLA
Sbjct: 840 DAKVPTYKYLA 850


>UniRef50_Q94AH6 Cluster: Cullin-1; n=13; Magnoliophyta|Rep:
           Cullin-1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 738

 Score = 71.3 bits (167), Expect = 7e-12
 Identities = 36/71 (50%), Positives = 48/71 (67%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  I +AIVRIM +RK L HQ LV E + QLS  FKP +  IKK ++ LI ++YLER 
Sbjct: 668 DRRYAIDAAIVRIMKSRKVLGHQQLVSECVEQLSRMFKPDIKAIKKRMEDLITRDYLERD 727

Query: 75  EGEKDTYRYLA 43
           +   + +RYLA
Sbjct: 728 KENPNMFRYLA 738


>UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involved
           in cell cycle control; n=5; Saccharomycetales|Rep:
           Ubiquitin ligase (Cullin) of SCF involved in cell cycle
           control - Pichia stipitis (Yeast)
          Length = 776

 Score = 70.9 bits (166), Expect = 9e-12
 Identities = 40/103 (38%), Positives = 61/103 (59%), Gaps = 1/103 (0%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GD-RKMLIQSAIVRIM*TRKTLKHQHLVVE 172
           YKSKKL+V +   +++               + R+  + + IVRIM +RKT+KH  L+ E
Sbjct: 676 YKSKKLKVNFTSVIKNNEAKQEEDDANKEIDETRRNYLSACIVRIMKSRKTVKHNELINE 735

Query: 171 VLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           VL Q  SRF  ++  IK+ ID LIEK+Y++R   + +TY YL+
Sbjct: 736 VLPQTLSRFHAKIIDIKRVIDQLIEKQYIQRI--DNNTYEYLS 776


>UniRef50_A5DRN9 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 528

 Score = 70.5 bits (165), Expect = 1e-11
 Identities = 31/70 (44%), Positives = 53/70 (75%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           RK+ + +AIVRI+ +R+T+ H  L+  ++ QLS+RF+P V ++K+ I+ LIEKEYL+R +
Sbjct: 459 RKIELNAAIVRILKSRRTVSHNELIEGLIRQLSNRFQPTVVMMKQRIEDLIEKEYLKRDD 518

Query: 72  GEKDTYRYLA 43
            +++ Y Y+A
Sbjct: 519 NDRNLYHYIA 528


>UniRef50_Q9ZVH4 Cluster: T2P11.2 protein; n=18; Magnoliophyta|Rep:
           T2P11.2 protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 732

 Score = 69.7 bits (163), Expect = 2e-11
 Identities = 35/71 (49%), Positives = 47/71 (66%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I++AIVRIM +RK L H +++ EV  QL  RF      IKK I+ LIE+++LER 
Sbjct: 662 DRKPQIEAAIVRIMKSRKILDHNNIIAEVTKQLQPRFLANPTEIKKRIESLIERDFLERD 721

Query: 75  EGEKDTYRYLA 43
             ++  YRYLA
Sbjct: 722 STDRKLYRYLA 732


>UniRef50_UPI0000364D21 Cluster: Cullin-3 (CUL-3).; n=1; Takifugu
           rubripes|Rep: Cullin-3 (CUL-3). - Takifugu rubripes
          Length = 768

 Score = 68.5 bits (160), Expect = 5e-11
 Identities = 34/71 (47%), Positives = 47/71 (66%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +RK  I++AIVRIM +R  L+H+ LV EV  QL   F P    +K+CI+ LIEKE+L RT
Sbjct: 698 ERKHRIEAAIVRIMKSRNRLQHKVLVAEVTQQLKKNFVPSHTAVKRCIEGLIEKEFLART 757

Query: 75  EGEKDTYRYLA 43
             ++  Y Y+A
Sbjct: 758 PEDQKAYIYVA 768


>UniRef50_Q237B9 Cluster: Cullin family protein; n=1; Tetrahymena
           thermophila SB210|Rep: Cullin family protein -
           Tetrahymena thermophila SB210
          Length = 765

 Score = 68.5 bits (160), Expect = 5e-11
 Identities = 29/70 (41%), Positives = 53/70 (75%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R+ ++ + IVRIM +RKT+KH  L  EV+ +L + FKP +P+IK+ I+ L++++YL+R 
Sbjct: 696 EREFIVDACIVRIMKSRKTMKHNDLFPEVI-KLINNFKPEIPLIKRRIESLLDRDYLKRD 754

Query: 75  EGEKDTYRYL 46
           E +++T+ Y+
Sbjct: 755 ENDRNTFIYV 764


>UniRef50_Q6BUD8 Cluster: Similar to CA5841|IPF420 Candida albicans
            IPF420; n=3; Saccharomycetaceae|Rep: Similar to
            CA5841|IPF420 Candida albicans IPF420 - Debaryomyces
            hansenii (Yeast) (Torulaspora hansenii)
          Length = 896

 Score = 68.5 bits (160), Expect = 5e-11
 Identities = 32/70 (45%), Positives = 50/70 (71%)
 Frame = -2

Query: 252  RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
            RK+ + +AIVRIM +R+T+ H  L+ E++ QL +RF+    +IK+ I+ LIEKEYL+R +
Sbjct: 827  RKIEVNAAIVRIMKSRRTINHNDLISELVKQLHNRFQTLTILIKQRIEDLIEKEYLKRDD 886

Query: 72   GEKDTYRYLA 43
             +K  Y Y+A
Sbjct: 887  NDKSIYHYVA 896


>UniRef50_UPI00005A31AC Cluster: PREDICTED: similar to Cullin-3
           (CUL-3); n=2; Euteleostomi|Rep: PREDICTED: similar to
           Cullin-3 (CUL-3) - Canis familiaris
          Length = 421

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 35/71 (49%), Positives = 47/71 (66%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I++AI+RI  +RK ++H  LV EV  Q+ +RF P   VIKK I+ LIE+EYL RT
Sbjct: 351 DRKHEIEAAILRITKSRKKMQHSVLVAEVTQQVKARFFPSTVVIKKHIEGLIEREYLART 410

Query: 75  EGEKDTYRYLA 43
             +   Y Y+A
Sbjct: 411 PEDCKVYTYVA 421


>UniRef50_A4RUG3 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 786

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 33/71 (46%), Positives = 46/71 (64%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I++ IVR+M  +K L H  +V+EV  Q+ +RF P    IKK I+ LIE+EY+ER 
Sbjct: 716 DRKPQIEATIVRVMKAKKRLDHNSIVMEVTAQVRNRFMPTPADIKKHIETLIEREYIERD 775

Query: 75  EGEKDTYRYLA 43
             ++  Y YLA
Sbjct: 776 PSDRKMYVYLA 786


>UniRef50_Q4QAA1 Cluster: Cullin-like protein-like protein; n=3;
           Leishmania|Rep: Cullin-like protein-like protein -
           Leishmania major
          Length = 744

 Score = 66.1 bits (154), Expect = 3e-10
 Identities = 33/70 (47%), Positives = 44/70 (62%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I  A+VRIM  R++L H  LV++   QLSSRF P V +IK+ I+ LI +EY+ R 
Sbjct: 674 DRKPAIDGALVRIMKGRRSLDHAELVLQCQQQLSSRFSPDVKLIKQRIEELIRREYISRD 733

Query: 75  EGEKDTYRYL 46
              K  Y Y+
Sbjct: 734 PRSKGVYHYI 743


>UniRef50_Q10CD7 Cluster: Cullin-4B, putative, expressed; n=8;
            Viridiplantae|Rep: Cullin-4B, putative, expressed - Oryza
            sativa subsp. japonica (Rice)
          Length = 836

 Score = 65.7 bits (153), Expect = 4e-10
 Identities = 41/102 (40%), Positives = 56/102 (54%)
 Frame = -2

Query: 348  YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
            Y+ K   ++ K TV++   +  R +      DR+  + +AIVRIM TRKTL H  L+ E+
Sbjct: 742  YRIKVNAIQMKETVEENTSTTERVFQ-----DRQYQVDAAIVRIMKTRKTLSHTLLITEL 796

Query: 168  LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
              QL    KP    IKK I+ LI++EYLER       Y YLA
Sbjct: 797  FQQLKFPIKP--SDIKKRIESLIDREYLERDRSNPQIYNYLA 836


>UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 750

 Score = 65.7 bits (153), Expect = 4e-10
 Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
 Frame = -2

Query: 354 SGYKSKKLRVKYKHTVQDGA*S*PRGYT----QTH*GDRKMLIQSAIVRIM*TRKTLKHQ 187
           S + SKK++V     VQ G      G      Q    +R   +Q+AIVRIM ++KT+ H 
Sbjct: 640 SKFSSKKMKVSCNIAVQIGETKQSEGQQTVSEQEIEKERFFKLQAAIVRIMKSKKTMTHN 699

Query: 186 HLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDT---YRYLA 43
            L VE   Q+S  F P++  IKK I+ LI++EY+ RT  +  +   Y Y+A
Sbjct: 700 DLTVETTTQVSKWFTPKITAIKKAIEYLIDQEYIRRTTDDNPSARKYEYMA 750


>UniRef50_UPI000049970B Cluster: cullin; n=1; Entamoeba histolytica
           HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
          Length = 728

 Score = 64.9 bits (151), Expect = 6e-10
 Identities = 30/69 (43%), Positives = 46/69 (66%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           RK+ +Q+ IVRIM  RK + +Q L  E++   S +F P   +IK+CI+ LIEKEY++R +
Sbjct: 659 RKVSLQAIIVRIMKQRKVIGYQQLKEEIMKISSYKFVPSTIMIKECIEFLIEKEYMKRKD 718

Query: 72  GEKDTYRYL 46
            +  TY Y+
Sbjct: 719 DDPSTYEYV 727


>UniRef50_A6S251 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 952

 Score = 64.9 bits (151), Expect = 6e-10
 Identities = 33/62 (53%), Positives = 42/62 (67%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR    Q+AIVRIM +RKT+ HQ+LV EV+NQ   R       IKK I+ LIEK+Y+ER 
Sbjct: 723 DRSFETQAAIVRIMKSRKTMTHQNLVAEVINQTKGRGAVEPAEIKKHIEKLIEKDYIERE 782

Query: 75  EG 70
           +G
Sbjct: 783 DG 784


>UniRef50_Q01BJ3 Cluster: Putative cullin; n=1; Ostreococcus
           tauri|Rep: Putative cullin - Ostreococcus tauri
          Length = 747

 Score = 64.5 bits (150), Expect = 8e-10
 Identities = 34/71 (47%), Positives = 47/71 (66%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  I +AIVR+M TRK+L H  L+ E++ QL  +F  +   +KK I+ LIE+EYLER 
Sbjct: 679 DRQQQIDAAIVRVMKTRKSLTHALLISELMAQL--KFPTKASDLKKRIESLIEREYLERD 736

Query: 75  EGEKDTYRYLA 43
             +  TY YLA
Sbjct: 737 REDAQTYNYLA 747


>UniRef50_UPI0000499E7A Cluster: cullin; n=1; Entamoeba histolytica
           HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
          Length = 721

 Score = 63.3 bits (147), Expect = 2e-09
 Identities = 27/70 (38%), Positives = 48/70 (68%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R  LI++ IVR+M   + ++H  L+  V+  LSSRF+  +P++++ I+ LIE+EY+ R+
Sbjct: 651 ERVGLIEACIVRLMKKNRKMQHNDLMQAVVTSLSSRFRTPIPLVRRTIESLIEREYISRS 710

Query: 75  EGEKDTYRYL 46
           +  KD Y Y+
Sbjct: 711 DVRKDEYIYI 720


>UniRef50_A0CT81 Cluster: Chromosome undetermined scaffold_27, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_27,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 740

 Score = 62.9 bits (146), Expect = 3e-09
 Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKP-RVPVIKKCIDMLIEKEYLER 79
           DR++ ++S IVR++ T+K L H+ L   +     +R  P  +P  K+CI+ LI+KEYL R
Sbjct: 669 DRRVYLESLIVRVLKTKKQLDHKDLFKYIDKDAKTRHFPIEIPFFKECIENLIQKEYLIR 728

Query: 78  TEGEKDTYRYLA 43
            EG+ DTY Y A
Sbjct: 729 QEGQLDTYIYKA 740


>UniRef50_A6QYU9 Cluster: Putative uncharacterized protein; n=1;
            Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
            protein - Ajellomyces capsulatus NAm1
          Length = 2249

 Score = 62.9 bits (146), Expect = 3e-09
 Identities = 36/70 (51%), Positives = 44/70 (62%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            DR    Q+AIVRIM  RK + H  L+VEV+N+  SR       IK  I+ LIEK+Y+ER 
Sbjct: 2181 DRHYETQAAIVRIMKARKVITHAELLVEVINKTKSRGVLEPAGIKTNIEKLIEKDYIERE 2240

Query: 75   EGEKDTYRYL 46
            EG K  YRYL
Sbjct: 2241 EGNK--YRYL 2248


>UniRef50_Q13620 Cluster: Cullin-4B; n=95; Eukaryota|Rep: Cullin-4B -
            Homo sapiens (Human)
          Length = 895

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 40/102 (39%), Positives = 60/102 (58%)
 Frame = -2

Query: 348  YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
            ++ K  +++ K TV++ A +  R +      DR+  I +AIVRIM  RKTL H  LV EV
Sbjct: 801  FRIKINQIQMKETVEEQASTTERVFQ-----DRQYQIDAAIVRIMKMRKTLSHNLLVSEV 855

Query: 168  LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
             NQL    KP    +KK I+ LI+++Y+ER +   + Y Y+A
Sbjct: 856  YNQLKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 895


>UniRef50_A0CBV9 Cluster: Chromosome undetermined scaffold_165,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_165,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 783

 Score = 62.1 bits (144), Expect = 4e-09
 Identities = 31/69 (44%), Positives = 47/69 (68%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R+ ++ S +VR+M +RKT+KH H ++E   Q+ S FKP +  IKK I+ LIE+EY+ R E
Sbjct: 715 REFVVDSQLVRLMKSRKTIKH-HELLENCQQMISIFKPDILFIKKRIENLIEREYIRRDE 773

Query: 72  GEKDTYRYL 46
            + + Y YL
Sbjct: 774 KDWNIYHYL 782


>UniRef50_Q5KDE6 Cluster: Ubiquitin-protein ligase, putative; n=1;
            Filobasidiella neoformans|Rep: Ubiquitin-protein ligase,
            putative - Cryptococcus neoformans (Filobasidiella
            neoformans)
          Length = 811

 Score = 62.1 bits (144), Expect = 4e-09
 Identities = 35/103 (33%), Positives = 59/103 (57%)
 Frame = -2

Query: 351  GYKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVE 172
            G+ S++++ K     QD +    R   +    DR  ++++ IVRIM +RK L  Q L+  
Sbjct: 709  GFTSERIKFKINQIQQDMSAEESRKTNEQVALDRVSILEATIVRIMKSRKKLTLQLLIDG 768

Query: 171  VLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
            V++ +S RF P V  IKK ++ LIE+E++ R E ++    Y+A
Sbjct: 769  VVSDVSKRFPPDVKEIKKRVESLIEREFMARDEEDRSILHYVA 811


>UniRef50_Q1DK65 Cluster: Putative uncharacterized protein; n=1;
            Coccidioides immitis|Rep: Putative uncharacterized
            protein - Coccidioides immitis
          Length = 2479

 Score = 61.7 bits (143), Expect = 6e-09
 Identities = 35/71 (49%), Positives = 46/71 (64%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            DR    Q+AIVRIM +RKT+  Q L+VEV+    +R       IKK ID LIEKEY+ER 
Sbjct: 2410 DRNYETQAAIVRIMKSRKTISPQELIVEVIKATRNRGDLDPADIKKNIDKLIEKEYMER- 2468

Query: 75   EGEKDTYRYLA 43
            + E + Y+Y+A
Sbjct: 2469 DTESNKYKYIA 2479


>UniRef50_Q4RTC1 Cluster: Chromosome 1 SCAF14998, whole genome shotgun
            sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 1
            SCAF14998, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 894

 Score = 61.3 bits (142), Expect = 8e-09
 Identities = 39/102 (38%), Positives = 60/102 (58%)
 Frame = -2

Query: 348  YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
            ++ K  +++ K TV++ A +  R +      DR+  I +AIVRIM  RKTL H  L+ EV
Sbjct: 800  FRIKINQIQMKETVEEQASTTERVFQ-----DRQYQIDAAIVRIMKMRKTLSHNLLMSEV 854

Query: 168  LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
             NQL    KP    +KK I+ LI+++Y+ER +   + Y Y+A
Sbjct: 855  YNQLKFPVKP--ADLKKRIESLIDRDYMERDKENSNQYNYVA 894


>UniRef50_Q17392 Cluster: Cullin-4; n=2; Caenorhabditis|Rep:
           Cullin-4 - Caenorhabditis elegans
          Length = 840

 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 33/71 (46%), Positives = 44/71 (61%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  I +A+VRIM  RK L HQ L+ E+L QL  RF      IKK ++ LIE+EY+ R 
Sbjct: 772 DRQYKIDAAVVRIMKARKQLNHQTLMTELLQQL--RFPVSTADIKKRLESLIEREYISRD 829

Query: 75  EGEKDTYRYLA 43
             E  +Y Y+A
Sbjct: 830 PEEASSYNYVA 840


>UniRef50_Q015Y9 Cluster: Cullin-like protein1; n=17;
           Viridiplantae|Rep: Cullin-like protein1 - Ostreococcus
           tauri
          Length = 812

 Score = 60.5 bits (140), Expect = 1e-08
 Identities = 28/71 (39%), Positives = 45/71 (63%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  I +AIVR M  RK+L +  L++EV++QL  +F P    IK  ++ LI KE++ER 
Sbjct: 742 DRRHAIDAAIVRTMKARKSLAYNQLIIEVVSQLKQKFVPEPKQIKIRVEELINKEFIERD 801

Query: 75  EGEKDTYRYLA 43
           +     ++Y+A
Sbjct: 802 KENPQVFKYMA 812


>UniRef50_A7RI48 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 746

 Score = 60.5 bits (140), Expect = 1e-08
 Identities = 25/45 (55%), Positives = 36/45 (80%)
 Frame = -2

Query: 177 VEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           ++V++Q  +RF P VP+IKKCI+ LI+K+YL+R EG KD Y Y+A
Sbjct: 702 LQVISQSRARFIPSVPMIKKCIEALIDKQYLDRQEGSKDEYSYVA 746


>UniRef50_Q09760 Cluster: Cullin-3; n=1; Schizosaccharomyces
           pombe|Rep: Cullin-3 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 785

 Score = 60.5 bits (140), Expect = 1e-08
 Identities = 31/70 (44%), Positives = 41/70 (58%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           RK    + IVR+M  RK  +H  L+ EV  QL+ RF P   +IK+ I+ LIE+EYL+R  
Sbjct: 716 RKHQADACIVRVMKDRKVCEHNQLMAEVTRQLNPRFHPSPMMIKRRIEALIEREYLQRQA 775

Query: 72  GEKDTYRYLA 43
                Y YLA
Sbjct: 776 DNGRIYEYLA 785


>UniRef50_Q54CS2 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 802

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 33/71 (46%), Positives = 47/71 (66%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  + +AIVRIM TRKTL H  L+ E+++ L  +F+P+   +KK I++LIEKEYL R 
Sbjct: 734 DRQYQVDAAIVRIMKTRKTLAHNLLISELVSLL--KFQPKPVDLKKRIEILIEKEYLCRD 791

Query: 75  EGEKDTYRYLA 43
                 Y Y+A
Sbjct: 792 PENAMIYNYMA 802


>UniRef50_Q7QJY4 Cluster: ENSANGP00000021534; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000021534 - Anopheles gambiae
           str. PEST
          Length = 740

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 31/71 (43%), Positives = 46/71 (64%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  I +AIVRIM  RKTL H  L+ E+  QL+   KP    +KK I+ LI+++Y+ER 
Sbjct: 672 DRQYQIDAAIVRIMKMRKTLSHNLLITELYKQLTFPVKP--ADLKKRIESLIDRDYMERD 729

Query: 75  EGEKDTYRYLA 43
           +  ++ Y Y+A
Sbjct: 730 KDNQNQYNYVA 740


>UniRef50_Q9VU33 Cluster: CG11261-PA; n=1; Drosophila
           melanogaster|Rep: CG11261-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 670

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 31/69 (44%), Positives = 44/69 (63%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R   + +AIVRIM  +K L++  L+  V  +L  R KP+V  IKK +D L+E+EYLER +
Sbjct: 603 RDKQVDAAIVRIMKGQKQLEYSELISLVYEELKDRVKPQVSFIKKRLDYLVEREYLER-D 661

Query: 72  GEKDTYRYL 46
              + YRYL
Sbjct: 662 NYYNIYRYL 670


>UniRef50_Q236I8 Cluster: Cullin family protein; n=1; Tetrahymena
           thermophila SB210|Rep: Cullin family protein -
           Tetrahymena thermophila SB210
          Length = 775

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 30/69 (43%), Positives = 48/69 (69%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R+ +I++ IVRIM +RKT+K+  LV EV N L  +F+ +   IKK I+ L+E+EY+ER 
Sbjct: 706 NREHVIEATIVRIMKSRKTMKYGELVSEV-NVLLRKFQTQPHQIKKRIESLVEREYIERD 764

Query: 75  EGEKDTYRY 49
           + + + Y Y
Sbjct: 765 KNDMNLYHY 773


>UniRef50_Q23CK5 Cluster: Cullin family protein; n=1; Tetrahymena
            thermophila SB210|Rep: Cullin family protein -
            Tetrahymena thermophila SB210
          Length = 882

 Score = 58.0 bits (134), Expect = 7e-08
 Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 3/73 (4%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLV---VEVLNQLSSRFKPRVPVIKKCIDMLIEKEYL 85
            +R  +I++ +VRIM  RK + H  L+   VE++   +  F+P  P I+KC + LIE+EY+
Sbjct: 809  ERTYIIKAYLVRIMKGRKVMAHNDLIKECVELIKTCARTFEPSFPHIRKCTESLIEEEYI 868

Query: 84   ERTEGEKDTYRYL 46
            +R E + + Y Y+
Sbjct: 869  KRQENDYNKYEYI 881


>UniRef50_O14122 Cluster: Cullin-4; n=1; Schizosaccharomyces
           pombe|Rep: Cullin-4 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 734

 Score = 58.0 bits (134), Expect = 7e-08
 Identities = 28/67 (41%), Positives = 43/67 (64%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  +Q++IVR+M  ++ +KH  LV  V+N +  R  P V  +K  I+ L+EKEYLER 
Sbjct: 666 DRQFELQASIVRVMKQKEKMKHDDLVQYVINNVKDRGIPLVSDVKTAIEKLLEKEYLERE 725

Query: 75  EGEKDTY 55
           + +  TY
Sbjct: 726 DNDIYTY 732


>UniRef50_Q7RZU1 Cluster: Putative uncharacterized protein NCU00272.1;
            n=1; Neurospora crassa|Rep: Putative uncharacterized
            protein NCU00272.1 - Neurospora crassa
          Length = 1039

 Score = 57.2 bits (132), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 42/71 (59%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            DR+   Q+AIVRIM +RK + H  LV EV+NQ   R       IK  I+ LIEK+Y+ER 
Sbjct: 972  DRQFETQAAIVRIMKSRKKMAHAQLVAEVINQTKQRGAVDAADIKANIEKLIEKDYIERE 1031

Query: 75   EGEKDTYRYLA 43
             G    Y YLA
Sbjct: 1032 GG---NYVYLA 1039


>UniRef50_UPI0000498BA9 Cluster: cullin; n=1; Entamoeba histolytica
           HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
          Length = 741

 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 27/70 (38%), Positives = 43/70 (61%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R  +IQ+  VRIM  R+T+K+  L+ E +  L SRF     + +K I+ LI KEY +R++
Sbjct: 672 RNYVIQAKQVRIMKQRRTMKYVDLINETIEHLRSRFNITSRMARKNIEYLINKEYFKRSD 731

Query: 72  GEKDTYRYLA 43
            +++   YLA
Sbjct: 732 SDREVLEYLA 741


>UniRef50_Q24CG0 Cluster: Cullin family protein; n=1; Tetrahymena
           thermophila SB210|Rep: Cullin family protein -
           Tetrahymena thermophila SB210
          Length = 729

 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 3/73 (4%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLV---VEVLNQLSSRFKPRVPVIKKCIDMLIEKEYL 85
           +R  +I++ +V+IM  RK + H  L+   VE++ + S  F+P    IK CI+ LIE+EY+
Sbjct: 656 ERTQIIKAYLVKIMKIRKVMAHNDLIKECVELIKKCSRTFEPCFLHIKNCIENLIEQEYI 715

Query: 84  ERTEGEKDTYRYL 46
           +R E +   Y+Y+
Sbjct: 716 KRIENDYKKYQYV 728


>UniRef50_A1CBL2 Cluster: Ubiquitin ligase subunit CulD, putative;
            n=3; Trichocomaceae|Rep: Ubiquitin ligase subunit CulD,
            putative - Aspergillus clavatus
          Length = 914

 Score = 54.0 bits (124), Expect = 1e-06
 Identities = 32/71 (45%), Positives = 43/71 (60%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            DR +  Q+AIVRIM +RK   H  LV EV+    SR    V  IK  I+ LIEK+Y+ER 
Sbjct: 847  DRHLETQAAIVRIMKSRKRSTHAELVAEVIKATRSRGVLEVADIKSNIEKLIEKDYIER- 905

Query: 75   EGEKDTYRYLA 43
              + + Y+Y+A
Sbjct: 906  --DDNVYQYVA 914


>UniRef50_Q5T2B5 Cluster: Cullin 2; n=18; Coelomata|Rep: Cullin 2 -
           Homo sapiens (Human)
          Length = 706

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 20/44 (45%), Positives = 34/44 (77%)
 Frame = -2

Query: 174 EVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           +V++Q  +RF P + +IKKCI++LI+K+Y+ER++   D Y Y+A
Sbjct: 663 QVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 706


>UniRef50_Q6CI31 Cluster: Similar to sp|O14122 Schizosaccharomyces
           pombe Cullin 4 homolog; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|O14122 Schizosaccharomyces pombe Cullin 4
           homolog - Yarrowia lipolytica (Candida lipolytica)
          Length = 755

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 31/71 (43%), Positives = 45/71 (63%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR M IQ+ I+RIM  R+T+ H  LV+EVL++  SR    V  +KK I  LI  +++ R 
Sbjct: 687 DRNMEIQAVIIRIMKARRTVGHAELVMEVLDKTKSRGILEVADVKKNISKLITDDFISR- 745

Query: 75  EGEKDTYRYLA 43
           +G +D Y Y+A
Sbjct: 746 QG-RDVYDYVA 755


>UniRef50_Q57YJ8 Cluster: Cullin, putative; n=2; Trypanosoma|Rep:
           Cullin, putative - Trypanosoma brucei
          Length = 742

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 28/71 (39%), Positives = 40/71 (56%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DRK  I + +VRIM +R+ L+H  LV E   +L   F     ++K+ I+ LI KE++ER 
Sbjct: 672 DRKPAIDACLVRIMKSRRVLEHSMLVEECKERLLPTFSADPKLVKQRIEELIRKEFIERD 731

Query: 75  EGEKDTYRYLA 43
                 YRY A
Sbjct: 732 ANTPGLYRYAA 742


>UniRef50_Q4CW84 Cluster: Putative uncharacterized protein; n=2;
            Trypanosoma cruzi|Rep: Putative uncharacterized protein -
            Trypanosoma cruzi
          Length = 1161

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 27/71 (38%), Positives = 43/71 (60%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            +R   +++ IVRIM  +++L H  L   V   L + F    PV K+C+  LIE+E++ R+
Sbjct: 1093 ERLRKLEAGIVRIMKEKRSLSHFDLFASVAELLMTHFVVTAPVFKRCMARLIEREFIARS 1152

Query: 75   EGEKDTYRYLA 43
              E+DTY Y+A
Sbjct: 1153 --ERDTYVYVA 1161


>UniRef50_Q23639 Cluster: Cullin-5; n=2; Caenorhabditis|Rep:
           Cullin-5 - Caenorhabditis elegans
          Length = 741

 Score = 52.4 bits (120), Expect = 4e-06
 Identities = 26/70 (37%), Positives = 43/70 (61%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R++ +Q  IV+I+ TRKT     L +E++  L   F P   +IK+ ID LIE +Y+ER  
Sbjct: 672 RELRVQEGIVKILKTRKTYTLAQLTMELVEILKPLFIPNRKIIKEQIDWLIENKYMERRA 731

Query: 72  GEKDTYRYLA 43
            + +T+ Y++
Sbjct: 732 DDINTFVYIS 741


>UniRef50_UPI0000498B52 Cluster: cullin; n=1; Entamoeba histolytica
           HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
          Length = 706

 Score = 52.0 bits (119), Expect = 5e-06
 Identities = 29/71 (40%), Positives = 41/71 (57%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR+  I + +VR+M   K +    L+  +  +L   FKP V  IK+ ID LIE+EYLE+ 
Sbjct: 638 DRETRIDAVVVRVMKKEKKMTVSELLTTITPKLD--FKPDVEEIKQRIDKLIEREYLEKD 695

Query: 75  EGEKDTYRYLA 43
           E  +D   YLA
Sbjct: 696 EKNEDVLLYLA 706


>UniRef50_A0CFE8 Cluster: Chromosome undetermined scaffold_175,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_175,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 724

 Score = 52.0 bits (119), Expect = 5e-06
 Identities = 31/72 (43%), Positives = 43/72 (59%)
 Frame = -2

Query: 258 GDRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLER 79
           GDRK+ IQ+AIVRIM  +KT   Q L+  V  QL   FKP    IK  I+ L+ +EYL+R
Sbjct: 654 GDRKIAIQAAIVRIMKGKKTQTFQQLIQLVKEQL-KMFKPNDIDIKDVIESLMNQEYLKR 712

Query: 78  TEGEKDTYRYLA 43
            +   +   Y++
Sbjct: 713 NQQNMNELIYVS 724


>UniRef50_P53202 Cluster: Cullin-3; n=2; Saccharomyces
           cerevisiae|Rep: Cullin-3 - Saccharomyces cerevisiae
           (Baker's yeast)
          Length = 744

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 25/68 (36%), Positives = 37/68 (54%)
 Frame = -2

Query: 246 MLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGE 67
           M + + IVRIM T   L HQ L+     +  SR      ++K+ I +LIEKEY++R   +
Sbjct: 677 MELSAIIVRIMKTEGKLSHQQLLERTTKRTQSRLSLTPSILKRSIQLLIEKEYIQRNADD 736

Query: 66  KDTYRYLA 43
              Y YL+
Sbjct: 737 PSYYHYLS 744


>UniRef50_Q4FKJ0 Cluster: Putative uncharacterized protein; n=1;
            Trypanosoma brucei|Rep: Putative uncharacterized protein
            - Trypanosoma brucei
          Length = 1166

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 40/71 (56%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            DRK  +++ I+++M  ++ L H  L      QL + F     + K+CI  LI+++YL R 
Sbjct: 1098 DRKKRLEAGIIQLMKAQQRLPHTELFAAARRQLQAHFPVTTSIFKQCISELIDRDYLARQ 1157

Query: 75   EGEKDTYRYLA 43
            +   DTY Y+A
Sbjct: 1158 DA--DTYIYVA 1166


>UniRef50_Q93034 Cluster: Cullin-5; n=38; Eumetazoa|Rep: Cullin-5 -
           Homo sapiens (Human)
          Length = 780

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 25/70 (35%), Positives = 43/70 (61%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R +  Q AI++IM  RK + +  L  E++  L + F P+  +IK+ I+ LIE +Y+ R E
Sbjct: 711 RILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDE 770

Query: 72  GEKDTYRYLA 43
            + +T+ Y+A
Sbjct: 771 SDINTFIYMA 780


>UniRef50_A5JZR9 Cluster: Cullin, putative; n=4; Plasmodium|Rep:
           Cullin, putative - Plasmodium vivax
          Length = 813

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 28/70 (40%), Positives = 42/70 (60%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           DR M I++AIVR+M   K L +  +   V   LS  F P   +I+K ID+L+E+EYL++ 
Sbjct: 745 DRTMAIEAAIVRVMKAHKKLFYDQIFDYVKKSLSC-FAPTNQIIEKKIDLLVEREYLQKE 803

Query: 75  EGEKDTYRYL 46
           E  +  Y Y+
Sbjct: 804 ENSQ-VYIYI 812


>UniRef50_UPI0000498870 Cluster: hypothetical protein 160.t00020;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 160.t00020 - Entamoeba histolytica HM-1:IMSS
          Length = 649

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 23/69 (33%), Positives = 41/69 (59%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R  ++ S +VRIM   K + +Q L    +++L   F P V ++KK ++ ++E EY +R E
Sbjct: 580 RFQMVISILVRIMKRLKRISYQDLCRLTVDELKKSFVPDVRILKKGVEYMLENEYAQRDE 639

Query: 72  GEKDTYRYL 46
            +K+T  Y+
Sbjct: 640 TDKNTLIYM 648


>UniRef50_Q236H3 Cluster: Cullin family protein; n=1; Tetrahymena
           thermophila SB210|Rep: Cullin family protein -
           Tetrahymena thermophila SB210
          Length = 784

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLN-QLSSRFKPRVPVIKKCIDMLIEKEYLER 79
           +RK +++S IV+IM +R+ ++HQ L  EV        F P    +K+C++ LI ++Y+  
Sbjct: 714 ERKFVVESLIVKIMKSRRKMEHQELYQEVARISQQHLFLPDQQTVKQCVNSLINRDYIRL 773

Query: 78  TEGEKDTYRYL 46
           +E  KD  +Y+
Sbjct: 774 SE-NKDYLQYV 783


>UniRef50_Q752S5 Cluster: AFR498Wp; n=1; Eremothecium gossypii|Rep:
           AFR498Wp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 727

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 24/70 (34%), Positives = 35/70 (50%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R   I +A+VR + T +T+ H  L    +  L   F     + K+ I  L+EKEY++R  
Sbjct: 658 RVQAISAAVVRQLKTERTMAHTELQDAAVRALQRHFAVSTSMFKRAIQSLLEKEYIQRDA 717

Query: 72  GEKDTYRYLA 43
              D Y YLA
Sbjct: 718 HSPDRYHYLA 727


>UniRef50_Q6FTV0 Cluster: Similar to sp|P53202 Saccharomyces
           cerevisiae YGR003w; n=1; Candida glabrata|Rep: Similar
           to sp|P53202 Saccharomyces cerevisiae YGR003w - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 757

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 40/70 (57%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R+ +  +AIVR+M + + L+   L  +   QL+ RF   +   K CI+ LIEKEY++R 
Sbjct: 687 ERQEVTNAAIVRLMKSERHLQFSELQEKTAVQLAQRFTLSLATFKACIETLIEKEYIQRD 746

Query: 75  EGEKDTYRYL 46
             + +   Y+
Sbjct: 747 VDDHEFLHYI 756


>UniRef50_Q4DVD1 Cluster: Putative uncharacterized protein; n=2;
            Trypanosoma cruzi|Rep: Putative uncharacterized protein -
            Trypanosoma cruzi
          Length = 1230

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 22/70 (31%), Positives = 43/70 (61%)
 Frame = -2

Query: 252  RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
            R++ + +AIVRIM +R++L++  L    + QLS +F P    +K  ++ L+ + +L R+E
Sbjct: 1161 RRIQMDAAIVRIMKSRRSLRYYELFDLTVQQLSKQFVPHPRSVKMQVEDLVCRGFLRRSE 1220

Query: 72   GEKDTYRYLA 43
             +   + Y+A
Sbjct: 1221 KDTSVFEYMA 1230


>UniRef50_UPI000150A116 Cluster: Cullin family protein; n=1;
           Tetrahymena thermophila SB210|Rep: Cullin family protein
           - Tetrahymena thermophila SB210
          Length = 752

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 26/68 (38%), Positives = 40/68 (58%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R+  + + IVRIM +RKTL    L  EV+  +   FKP+   IK+ I+ LIE++YL R  
Sbjct: 683 REHQLDACIVRIMKSRKTLALNDLNAEVVKLIGHIFKPQPQQIKQRIESLIERDYLIRHI 742

Query: 72  GEKDTYRY 49
            ++  + Y
Sbjct: 743 DDRTKFIY 750


>UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein
           isoform 3; n=1; Bos taurus|Rep: PREDICTED: hypothetical
           protein isoform 3 - Bos taurus
          Length = 776

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 22/57 (38%), Positives = 32/57 (56%)
 Frame = -1

Query: 211 NAQDP*ASAPSGGSPQPVVVTVQAQSSCHQEMHRYAD*EGIFRAYRGREGHLQIPGV 41
           N + P   A +  SP   V+ +QA    + EMH ++D EG+  A    EGHLQ+PG+
Sbjct: 720 NEEGPKTPAVTWRSPDSAVLKIQAPGPSNXEMHXHSDREGVSGASGRGEGHLQLPGL 776


>UniRef50_Q24DT3 Cluster: Cullin family protein; n=1; Tetrahymena
           thermophila SB210|Rep: Cullin family protein -
           Tetrahymena thermophila SB210
          Length = 734

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 28/102 (27%), Positives = 51/102 (50%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           Y+SKK  +K     +       +  T     +R  ++ ++IV+I+ ++K + HQ L+ E+
Sbjct: 635 YQSKKKLIKVNSIFKKETKEDVKETTDRVLTERGFVLDASIVKILKSKKNIYHQELMKEL 694

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
            N L          +KK I+ LI++EY++R       Y Y+A
Sbjct: 695 FNDLMLPIN--ASEVKKRIEGLIDREYMKRDPENHSLYHYVA 734


>UniRef50_UPI0000E47A13 Cluster: PREDICTED: similar to MGC80402
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80402 protein -
           Strongylocentrotus purpuratus
          Length = 79

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 22/43 (51%), Positives = 27/43 (62%)
 Frame = -2

Query: 171 VLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           V  QL SRF P   VIKK I+ LIE+EYL R   ++  Y Y+A
Sbjct: 37  VTEQLKSRFLPSPVVIKKRIESLIEREYLARAPEDRKVYTYVA 79


>UniRef50_Q4QEP5 Cluster: Putative uncharacterized protein; n=2;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 2202

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 21/70 (30%), Positives = 43/70 (61%)
 Frame = -2

Query: 252  RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
            R++L+ +A+VRI  +R+ +  + L   V   LS +F P    +K  ++ LI+++Y++R+ 
Sbjct: 2133 RRVLLDAALVRIFKSRRVVLFEDLFQTVTAHLSRQFMPSRRDVKAQLEGLIDRDYVKRSP 2192

Query: 72   GEKDTYRYLA 43
               +T+ YL+
Sbjct: 2193 DNPNTFVYLS 2202


>UniRef50_A0C548 Cluster: Chromosome undetermined scaffold_15, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_15,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 429

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 34/102 (33%), Positives = 50/102 (49%)
 Frame = -2

Query: 348 YKSKKLRVKYKHTVQDGA*S*PRGYTQTH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEV 169
           ++SKK  +K     +          TQ    DRK +I ++IV+IM   K    Q +V  V
Sbjct: 330 FESKKTHIKINQMQKIEKKEEIEENTQKLLHDRKYVIDASIVKIMKRDKQHTLQEIVNLV 389

Query: 168 LNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDTYRYLA 43
           L  L    K     IK+ I++L EKEYL+R + +   + YLA
Sbjct: 390 LKDLGLPLK--AVDIKQQIEVLTEKEYLQRDQNDMSLFIYLA 429


>UniRef50_Q5CP75 Cluster: Cullin 1 protein-related; n=2;
           Cryptosporidium|Rep: Cullin 1 protein-related -
           Cryptosporidium hominis
          Length = 826

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 24/71 (33%), Positives = 39/71 (54%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           D+   I++AIV+IM  +  +    ++  V +QL   +KP   +I   I  LIE+EYLE  
Sbjct: 757 DKSHAIEAAIVKIMKIKGQMTRSDIIAHVSSQLCD-YKPSERMIIDKIKYLIEREYLENN 815

Query: 75  EGEKDTYRYLA 43
           + + +   YLA
Sbjct: 816 QDDPEKLLYLA 826


>UniRef50_Q4Q1I0 Cluster: Putative uncharacterized protein; n=3;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 1925

 Score = 41.1 bits (92), Expect = 0.009
 Identities = 26/75 (34%), Positives = 38/75 (50%)
 Frame = -2

Query: 267  TH*GDRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEY 88
            T+  D    I+  IVRIM   + L H+ LV  V   L  +        K C+  LIEKE+
Sbjct: 1853 TYSADSAHKIKVCIVRIMKAERVLPHRELVERVALALEGQLVVTPSQFKCCVAYLIEKEF 1912

Query: 87   LERTEGEKDTYRYLA 43
            L+R  GE+  Y +++
Sbjct: 1913 LQR--GEQGEYVFVS 1925


>UniRef50_A0BLH1 Cluster: Chromosome undetermined scaffold_114,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_114,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 767

 Score = 41.1 bits (92), Expect = 0.009
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPV--IKKCIDMLIEKEYLE 82
           D+ + I++AIV+IM  +K ++   LV++V   +       +P   IK+ I+ L   EYLE
Sbjct: 696 DKDLAIEAAIVKIMKKQKEMQFSDLVIQVQGHMKKNQNVEIPFAQIKQMIERLQRNEYLE 755

Query: 81  RTEGEKDTYRY 49
           R        +Y
Sbjct: 756 RDANNMQLIKY 766


>UniRef50_A2FHP4 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 641

 Score = 39.5 bits (88), Expect = 0.027
 Identities = 19/63 (30%), Positives = 37/63 (58%)
 Frame = -2

Query: 240 IQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKD 61
           I++A  + + +R++     +V  V N L  +F P    I+KC++ L+E+EY+    G ++
Sbjct: 575 IEAATYKFLKSRRSATVDEIVEAVYNVLRPKFDPPREDIEKCLNKLVEREYIIPHGGLQN 634

Query: 60  TYR 52
           +YR
Sbjct: 635 SYR 637


>UniRef50_Q383D5 Cluster: Cullin 1, putative; n=1; Trypanosoma
           brucei|Rep: Cullin 1, putative - Trypanosoma brucei
          Length = 805

 Score = 38.7 bits (86), Expect = 0.047
 Identities = 17/64 (26%), Positives = 32/64 (50%)
 Frame = -2

Query: 237 QSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKDT 58
           Q+ ++R   +  T     L   V N+  +  KP +  +K  ++ LI +E++ R E   DT
Sbjct: 741 QATLIRAFKSEGTASFSQLFERVENESPAHLKPSIQQMKVALEFLISREFVRRNEDGTDT 800

Query: 57  YRYL 46
           + Y+
Sbjct: 801 FSYV 804


>UniRef50_A7TKA1 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 765

 Score = 37.9 bits (84), Expect = 0.081
 Identities = 20/70 (28%), Positives = 37/70 (52%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R   + ++++R M + K L    L   + N +  RF+ +  +  K ID LI+KEYL++ 
Sbjct: 695 ERLQEVNASVIREMKSNKILTINELESTITNIVKDRFQLQHNLFIKSIDYLIDKEYLQKD 754

Query: 75  EGEKDTYRYL 46
             + +   YL
Sbjct: 755 IDDTELLHYL 764


>UniRef50_Q57XW2 Cluster: Cullin 4B, putative; n=1; Trypanosoma
            brucei|Rep: Cullin 4B, putative - Trypanosoma brucei
          Length = 947

 Score = 35.9 bits (79), Expect = 0.33
 Identities = 22/71 (30%), Positives = 38/71 (53%)
 Frame = -2

Query: 255  DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
            DR  ++ +AIVR+M  R+   H+ ++ EV   +  RF      +K+    L E+ +LER 
Sbjct: 881  DRVHVVDAAIVRLMKQRRRASHEEVMEEVPKLV--RFPVTASAVKESARRLTERGFLER- 937

Query: 75   EGEKDTYRYLA 43
             G  + Y Y++
Sbjct: 938  -GNTNEYIYIS 947


>UniRef50_UPI0000D8A8BE Cluster: UPI0000D8A8BE related cluster; n=1;
           Mus musculus|Rep: UPI0000D8A8BE UniRef100 entry - Mus
           musculus
          Length = 393

 Score = 35.5 bits (78), Expect = 0.43
 Identities = 23/69 (33%), Positives = 39/69 (56%)
 Frame = -2

Query: 252 RKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTE 73
           R+  I + +VRI   ++ L H  LV E+ NQL  +F P  P   K I+ LI+++Y+E+ +
Sbjct: 327 RQCKIDAVVVRIKKMQRILGHYLLVSELYNQL--KF-PVKPGYLKRIESLIDRDYMEQDK 383

Query: 72  GEKDTYRYL 46
              +   Y+
Sbjct: 384 DSPNQDHYV 392


>UniRef50_Q4D5L7 Cluster: Cullin 2, putative; n=2; Trypanosoma
           cruzi|Rep: Cullin 2, putative - Trypanosoma cruzi
          Length = 810

 Score = 35.5 bits (78), Expect = 0.43
 Identities = 16/65 (24%), Positives = 33/65 (50%)
 Frame = -2

Query: 240 IQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKD 61
           +Q+ +VR+     TL    L+ +V ++   +F P V  +K  ++ LI + ++ R      
Sbjct: 745 VQATLVRVFKASGTLSFYELMEKVKDESLQKFMPSVQQVKVALEFLISRGFVIRDNSNGG 804

Query: 60  TYRYL 46
           T+ Y+
Sbjct: 805 TFSYI 809


>UniRef50_Q5AA44 Cluster: Putative uncharacterized protein RTT101;
           n=1; Candida albicans|Rep: Putative uncharacterized
           protein RTT101 - Candida albicans (Yeast)
          Length = 288

 Score = 34.3 bits (75), Expect = 1.0
 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
 Frame = -2

Query: 240 IQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPV----IKKCIDMLIEKEYLERTE 73
           I+S +V+IM   + L     ++E+LN+  S  + R PV    +K  I+ LIE EYL+R +
Sbjct: 223 IKSCVVKIMKQERQLT----IIELLNKSISVLQNRRPVTMTNLKTIIENLIELEYLKRDD 278

Query: 72  GEKDTYRYL 46
             K+   Y+
Sbjct: 279 HNKNIIIYI 287


>UniRef50_A3GFR1 Cluster: Cullin, ubiquitin ligase activity; n=2;
           Pichia stipitis|Rep: Cullin, ubiquitin ligase activity -
           Pichia stipitis (Yeast)
          Length = 783

 Score = 33.9 bits (74), Expect = 1.3
 Identities = 19/62 (30%), Positives = 32/62 (51%)
 Frame = -2

Query: 240 IQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKD 61
           ++ AIV++M   K L    L+ + +  +  R    +  +KK ID L++ EYL R + E  
Sbjct: 720 LKGAIVKVMKEFKQLSVTELLNKAIEGVEKRGPVTLTELKKNIDDLVDSEYLRRVDRETL 779

Query: 60  TY 55
            Y
Sbjct: 780 AY 781


>UniRef50_UPI0000498755 Cluster: cullin; n=1; Entamoeba histolytica
           HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
          Length = 672

 Score = 32.7 bits (71), Expect = 3.1
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLER 79
           DR    ++  VR+M   K  +   L+  V+ +  + F P    ++  I+ LIEKEY+ER
Sbjct: 604 DRSAWGEAVCVRLMKKMKKCRELDLINMVIKE-KAPFIPTEQFVQNVIEKLIEKEYIER 661


>UniRef50_A0BJA6 Cluster: Chromosome undetermined scaffold_11, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_11,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 782

 Score = 32.7 bits (71), Expect = 3.1
 Identities = 21/69 (30%), Positives = 33/69 (47%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           +R + IQS+IVR+M T K + +  +   V   L   +      I   ID LI   Y++R 
Sbjct: 711 ERDLKIQSSIVRLMKTNKEMYYHQICAGVQKGLLGYYDFFSQDILAQIDELINSNYIKRD 770

Query: 75  EGEKDTYRY 49
           E   + + Y
Sbjct: 771 ERINNKFLY 779


>UniRef50_Q4CRP5 Cluster: Putative uncharacterized protein; n=2;
            Trypanosoma cruzi|Rep: Putative uncharacterized protein -
            Trypanosoma cruzi
          Length = 1017

 Score = 32.3 bits (70), Expect = 4.0
 Identities = 19/66 (28%), Positives = 36/66 (54%)
 Frame = -2

Query: 240  IQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEKD 61
            IQ+ I++ M + +T  +  L      Q + +F+ +    K  ++MLIEKE+++R   +K 
Sbjct: 953  IQAVIIKHMKSVRTCLYDELFCWTRQQ-NPQFQLQNSDFKLALEMLIEKEFVQRDPSQKQ 1011

Query: 60   TYRYLA 43
             + Y A
Sbjct: 1012 RFVYKA 1017


>UniRef50_Q4Q9W5 Cluster: Putative uncharacterized protein; n=3;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 1171

 Score = 31.9 bits (69), Expect = 5.3
 Identities = 22/67 (32%), Positives = 36/67 (53%)
 Frame = -2

Query: 243  LIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERTEGEK 64
            L++ AIV  + +++T+    L   V  ++   F     V+KK ID LIE+ ++ R  G+ 
Sbjct: 1109 LVEVAIVSCLKSQRTMTRTDLASAVAARVP--FPVTTTVLKKAIDKLIERGFMIR--GKG 1164

Query: 63   DTYRYLA 43
             TY Y A
Sbjct: 1165 STYVYSA 1171


>UniRef50_A7TQC4 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 487

 Score = 31.9 bits (69), Expect = 5.3
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
 Frame = -2

Query: 210 TRKTLK-HQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIE--KEYLERTEGEKDTY 55
           T KTL  H  ++  + N LS++     PV + C D LI+  K   + T  E+DTY
Sbjct: 121 TSKTLSTHVSVLSNLFNILSAKSSIDYPVCQDCCDWLIQRLKSQYDETIKERDTY 175


>UniRef50_A7KAI5 Cluster: Atg6p; n=1; Pichia angusta|Rep: Atg6p -
           Pichia angusta (Yeast) (Hansenula polymorpha)
          Length = 443

 Score = 31.9 bits (69), Expect = 5.3
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
 Frame = -2

Query: 171 VLNQLSSRFKPRVPVIKKCIDMLIE--KEYLERTEGEKDTY 55
           + N LSS+++   PV   C   LIE  K+  E+   EKDTY
Sbjct: 114 IFNILSSKYEIDYPVCTDCASTLIEELKQQFEQMTKEKDTY 154


>UniRef50_Q5CUH7 Cluster: Cullin domain containing protein; n=2;
           Cryptosporidium|Rep: Cullin domain containing protein -
           Cryptosporidium parvum Iowa II
          Length = 851

 Score = 31.5 bits (68), Expect = 7.1
 Identities = 18/70 (25%), Positives = 34/70 (48%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERT 76
           D+  +I S IVR +   KTL    +   V+N           +I + ++ML +KE++ + 
Sbjct: 781 DKGYIIDSIIVRNLKKNKTLHIDDITRRVINHNDVLLHGSTELIVERLEMLCQKEFVSKD 840

Query: 75  EGEKDTYRYL 46
              ++ Y Y+
Sbjct: 841 LFSQNLYSYV 850


>UniRef50_A2FN39 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 697

 Score = 31.5 bits (68), Expect = 7.1
 Identities = 20/59 (33%), Positives = 30/59 (50%)
 Frame = -2

Query: 255 DRKMLIQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLER 79
           DR  +I +AI RIM   KT+  + L   V  +LS +F        K + + I + Y+ER
Sbjct: 629 DRDRIINAAICRIMKHEKTMFEKDLWNRVYIELSQKFPLTRSDFSKNLALAISQGYVER 687


>UniRef50_A2E3X9 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 645

 Score = 31.5 bits (68), Expect = 7.1
 Identities = 14/53 (26%), Positives = 29/53 (54%)
 Frame = -2

Query: 240 IQSAIVRIM*TRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLE 82
           I   I RI+  ++ +    L  +V+N+LSS F P    +   +  L+E+++++
Sbjct: 583 INCKITRILKDKRAMSIPALTTQVINELSSFFIPTESEVNHSLQTLVERDFVK 635


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 380,638,144
Number of Sequences: 1657284
Number of extensions: 6782679
Number of successful extensions: 17606
Number of sequences better than 10.0: 111
Number of HSP's better than 10.0 without gapping: 17215
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17580
length of database: 575,637,011
effective HSP length: 92
effective length of database: 423,166,883
effective search space used: 19042509735
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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