Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--0417
(345 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxyl... 54 9e-08
S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto... 54 9e-08
S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain ... 54 9e-08
J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto... 54 9e-08
BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto aci... 54 9e-08
BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto aci... 54 9e-08
BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto aci... 54 9e-08
AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein. 54 9e-08
AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto aci... 54 9e-08
M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human branched-... 51 8e-07
Z84466-9|CAI42469.1| 186|Homo sapiens v-raf murine sarcoma 3611... 29 3.9
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 29 3.9
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 29 3.9
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 29 3.9
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 29 3.9
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 29 3.9
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 29 3.9
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 29 3.9
AB208831-1|BAD92068.1| 188|Homo sapiens v-raf murine sarcoma 36... 29 3.9
AB158254-1|BAE66645.1| 186|Homo sapiens Ras-binding protein DA-... 29 3.9
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 28 6.8
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 28 6.8
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 28 6.8
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 28 6.8
>Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxylase
alpha subunit protein.
Length = 445
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 52 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 107
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 107 KSMTLLNTMDRILYESQRQGRISFYMTNY 135
>S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto
acid dehydrogenase E1 alpha subunit protein.
Length = 443
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 50 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 105
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 105 KSMTLLNTMDRILYESQRQGRISFYMTNY 133
>S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain
alpha-keto acid dehydrogenase complex E1 alpha subunit
[human, Genomic, 195 nt, segment 8 of 8]. ).
Length = 387
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 50 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 105
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 105 KSMTLLNTMDRILYESQRQGRISFYMTNY 133
>J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto
acid dehydrogenase protein.
Length = 444
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 51 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 106
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 106 KSMTLLNTMDRILYESQRQGRISFYMTNY 134
>BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 52 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 107
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 107 KSMTLLNTMDRILYESQRQGRISFYMTNY 135
>BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 52 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 107
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 107 KSMTLLNTMDRILYESQRQGRISFYMTNY 135
>BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 52 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 107
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 107 KSMTLLNTMDRILYESQRQGRISFYMTNY 135
>AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein.
Length = 479
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 86 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 141
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 141 KSMTLLNTMDRILYESQRQGRISFYMTNY 169
>AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide variant protein.
Length = 444
Score = 54.4 bits (125), Expect = 9e-08
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 93 PEFPGARAPYLSEMKFFNETSYEPIPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
P+FPGA A ++ +++F IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 52 PQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 107
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 107 KSMTLLNTMDRILYESQRQGRISFYMTNY 135
>M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human
branched-chain alpha-keto acid dehydrogenase E1-alpha
subunit (BCKDH) mRNA, partial cds. ).
Length = 378
Score = 51.2 bits (117), Expect = 8e-07
Identities = 22/29 (75%), Positives = 26/29 (89%)
Frame = +2
Query: 257 KTMVQLSHMDKIIYESQRQGRISFYMTNY 343
K+M L+ MD+I+YESQRQGRISFYMTNY
Sbjct: 40 KSMTLLNTMDRILYESQRQGRISFYMTNY 68
Score = 37.1 bits (82), Expect = 0.015
Identities = 16/32 (50%), Positives = 23/32 (71%)
Frame = +3
Query: 165 IPIYPVMDNNGQIIDLNEEPNLDKATLINMSK 260
IPIY VMD GQII+ +E+P+L K ++ + K
Sbjct: 9 IPIYRVMDRQGQIINPSEDPHLPKEKVLKLYK 40
>Z84466-9|CAI42469.1| 186|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 186
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for
A-raf-1 oncogene. ).
Length = 606
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase
protein.
Length = 606
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein.
Length = 606
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog 1 protein.
Length = 606
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein.
Length = 609
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>AB208831-1|BAD92068.1| 188|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog variant protein.
Length = 188
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 93 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 134
>AB158254-1|BAE66645.1| 186|Homo sapiens Ras-binding protein DA-Raf
protein.
Length = 186
Score = 29.1 bits (62), Expect = 3.9
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Frame = -2
Query: 209 VDDLPVIIHNWINRNWFITSFVE---EFHFTQVRC-SCARKF 96
++D+P+ +HN++ + +F +F + +F F RC +C KF
Sbjct: 91 LEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKF 132
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 28.3 bits (60), Expect = 6.8
Identities = 13/30 (43%), Positives = 20/30 (66%)
Frame = -3
Query: 115 ALAPGNSGYLTTAIMCRFGPRTGRQKPSSP 26
++AP N+G TT++ CR PR G +P+ P
Sbjct: 280 SVAPSNTGSRTTSVRCRGIPR-GPVRPAIP 308
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 28.3 bits (60), Expect = 6.8
Identities = 13/30 (43%), Positives = 20/30 (66%)
Frame = -3
Query: 115 ALAPGNSGYLTTAIMCRFGPRTGRQKPSSP 26
++AP N+G TT++ CR PR G +P+ P
Sbjct: 280 SVAPSNTGSRTTSVRCRGIPR-GPVRPAIP 308
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 28.3 bits (60), Expect = 6.8
Identities = 13/30 (43%), Positives = 20/30 (66%)
Frame = -3
Query: 115 ALAPGNSGYLTTAIMCRFGPRTGRQKPSSP 26
++AP N+G TT++ CR PR G +P+ P
Sbjct: 280 SVAPSNTGSRTTSVRCRGIPR-GPVRPAIP 308
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 28.3 bits (60), Expect = 6.8
Identities = 13/30 (43%), Positives = 20/30 (66%)
Frame = -3
Query: 115 ALAPGNSGYLTTAIMCRFGPRTGRQKPSSP 26
++AP N+G TT++ CR PR G +P+ P
Sbjct: 280 SVAPSNTGSRTTSVRCRGIPR-GPVRPAIP 308
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 51,930,268
Number of Sequences: 237096
Number of extensions: 939591
Number of successful extensions: 1534
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 1485
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1534
length of database: 76,859,062
effective HSP length: 80
effective length of database: 57,891,382
effective search space used: 1968306988
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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