BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ce--0324 (672 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 131 2e-30 BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 131 2e-30 AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 131 2e-30 AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 131 2e-30 M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 129 8e-30 BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 129 8e-30 X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 128 2e-29 U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 128 2e-29 L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 128 2e-29 BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 128 2e-29 AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 128 2e-29 AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 128 2e-29 AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 128 2e-29 AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 128 2e-29 AB045122-1|BAB40980.1| 44|Homo sapiens ME2 protein. 49 2e-05 AF218002-1|AAG17244.1| 554|Homo sapiens unknown protein. 30 8.7 >X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxaloacetate decarboxylating) (NADP+) protein. Length = 604 Score = 131 bits (317), Expect = 2e-30 Identities = 57/85 (67%), Positives = 70/85 (82%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +YI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDK Sbjct: 106 KYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 165 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ +L +WPE +++A+VVTDGER Sbjct: 166 GHLATMLNSWPEDNIKAVVVTDGER 190 Score = 56.0 bits (129), Expect = 1e-07 Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 8/194 (4%) Frame = +1 Query: 85 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSI 264 G D ++P LNKGMAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+ I Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYII 109 Query: 265 LWGSWTAMSICSTVSSRITWLK*CQLCTLRRLAWPVRSSGLCTADQGASSSRS-----TI 429 L M++ + + + + + GL G + R TI Sbjct: 110 L------MTLQDRNEKLFYRVLTSDVEKFMPIVY-TPTVGLACQHYGLTFRRPRGLFITI 162 Query: 430 RD---MYTMFLRTGRRRTSAPLL*PTENVFGPGRFGRLRDGHPCGQTRALHRASEASSPQ 600 D + TM A ++ E + G G G G P G+ AL+ A +PQ Sbjct: 163 HDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL-ALYTACGGVNPQ 221 Query: 601 SMVYPSLSNVGTNN 642 + P L +VGTNN Sbjct: 222 QCL-PVLLDVGTNN 234 Score = 46.4 bits (105), Expect = 9e-05 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 192 LGLGDLGCYGMGIPVGKLALYTA 214 >BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)-dependent, mitochondrial protein. Length = 604 Score = 131 bits (317), Expect = 2e-30 Identities = 57/85 (67%), Positives = 70/85 (82%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +YI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDK Sbjct: 106 KYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 165 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ +L +WPE +++A+VVTDGER Sbjct: 166 GHLATMLNSWPEDNIKAVVVTDGER 190 Score = 54.0 bits (124), Expect = 5e-07 Identities = 58/194 (29%), Positives = 85/194 (43%), Gaps = 8/194 (4%) Frame = +1 Query: 85 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSI 264 G D ++P LNKGMAFT+EER LGIHGL+PP Q+ Q+ +R ++ L+ I Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLGQDVQLLRIMGYYERQQSDLDKYII 109 Query: 265 LWGSWTAMSICSTVSSRITWLK*CQLCTLRRLAWPVRSSGLCTADQGASSSRS-----TI 429 L M++ + + + + + GL G + R TI Sbjct: 110 L------MTLQDRNEKLFYRVLTSDVEKFMPIVY-TPTVGLACQHYGLTFRRPRGLFITI 162 Query: 430 RD---MYTMFLRTGRRRTSAPLL*PTENVFGPGRFGRLRDGHPCGQTRALHRASEASSPQ 600 D + TM A ++ E + G G G G P G+ AL+ A +PQ Sbjct: 163 HDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL-ALYTACGGVNPQ 221 Query: 601 SMVYPSLSNVGTNN 642 + P L +VGTNN Sbjct: 222 QCL-PVLLDVGTNN 234 Score = 46.4 bits (105), Expect = 9e-05 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 192 LGLGDLGCYGMGIPVGKLALYTA 214 >AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-dependent malic enzyme 3 protein. Length = 259 Score = 131 bits (317), Expect = 2e-30 Identities = 57/85 (67%), Positives = 70/85 (82%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +YI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDK Sbjct: 44 KYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 103 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ +L +WPE +++A+VVTDGER Sbjct: 104 GHLATMLNSWPEDNIKAVVVTDGER 128 Score = 46.4 bits (105), Expect = 9e-05 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 130 LGLGDLGCYGMGIPVGKLALYTA 152 Score = 41.5 bits (93), Expect = 0.003 Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 8/181 (4%) Frame = +1 Query: 124 MAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWGSWTAMSICST 303 MAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+ IL M++ Sbjct: 1 MAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIIL------MTLQDR 54 Query: 304 VSSRITWLK*CQLCTLRRLAWPVRSSGLCTADQGASSSRS-----TIRD---MYTMFLRT 459 + + + + + GL G + R TI D + TM Sbjct: 55 NEKLFYRVLTSDVEKFMPIVY-TPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSW 113 Query: 460 GRRRTSAPLL*PTENVFGPGRFGRLRDGHPCGQTRALHRASEASSPQSMVYPSLSNVGTN 639 A ++ E + G G G G P G+ AL+ A +PQ + P L +VGTN Sbjct: 114 PEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL-ALYTACGGVNPQQCL-PVLLDVGTN 171 Query: 640 N 642 N Sbjct: 172 N 172 >AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC 1.1.1.40). ). Length = 252 Score = 131 bits (317), Expect = 2e-30 Identities = 57/85 (67%), Positives = 70/85 (82%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +YI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDK Sbjct: 44 KYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 103 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ +L +WPE +++A+VVTDGER Sbjct: 104 GHLATMLNSWPEDNIKAVVVTDGER 128 Score = 46.4 bits (105), Expect = 9e-05 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 130 LGLGDLGCYGMGIPVGKLALYTA 152 Score = 41.5 bits (93), Expect = 0.003 Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 8/181 (4%) Frame = +1 Query: 124 MAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWGSWTAMSICST 303 MAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+ IL M++ Sbjct: 1 MAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIIL------MTLQDR 54 Query: 304 VSSRITWLK*CQLCTLRRLAWPVRSSGLCTADQGASSSRS-----TIRD---MYTMFLRT 459 + + + + + GL G + R TI D + TM Sbjct: 55 NEKLFYRVLTSDVEKFMPIVY-TPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSW 113 Query: 460 GRRRTSAPLL*PTENVFGPGRFGRLRDGHPCGQTRALHRASEASSPQSMVYPSLSNVGTN 639 A ++ E + G G G G P G+ AL+ A +PQ + P L +VGTN Sbjct: 114 PEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL-ALYTACGGVNPQQCL-PVLLDVGTN 171 Query: 640 N 642 N Sbjct: 172 N 172 >M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -dependent malic enzyme protein. Length = 584 Score = 129 bits (312), Expect = 8e-30 Identities = 52/85 (61%), Positives = 71/85 (83%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +YIY+MG+ +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+ Sbjct: 81 KYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDR 140 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GHV ++ NWPE V+A+VVTDGER Sbjct: 141 GHVRSIVDNWPENHVKAVVVTDGER 165 Score = 56.0 bits (129), Expect = 1e-07 Identities = 24/57 (42%), Positives = 38/57 (66%) Frame = +1 Query: 103 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWG 273 +P NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL + G Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMG 87 Score = 44.8 bits (101), Expect = 3e-04 Identities = 20/23 (86%), Positives = 20/23 (86%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKL LYTA Sbjct: 167 LGLGDLGVYGMGIPVGKLCLYTA 189 >BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. Length = 479 Score = 129 bits (312), Expect = 8e-30 Identities = 52/85 (61%), Positives = 71/85 (83%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +YIY+MG+ +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+ Sbjct: 81 KYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDR 140 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GHV ++ NWPE V+A+VVTDGER Sbjct: 141 GHVRSIVDNWPENHVKAVVVTDGER 165 Score = 56.0 bits (129), Expect = 1e-07 Identities = 24/57 (42%), Positives = 38/57 (66%) Frame = +1 Query: 103 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWG 273 +P NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL + G Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMG 87 Score = 44.8 bits (101), Expect = 3e-04 Identities = 20/23 (86%), Positives = 20/23 (86%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKL LYTA Sbjct: 167 LGLGDLGVYGMGIPVGKLCLYTA 189 >X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxaloacetate decarboxylating) (NADP+) protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent malic enzyme protein. Length = 565 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 64 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 123 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 124 GHIASVLNAWPEDVIKAIVVTDGER 148 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 13 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 48 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 150 LGLGDLGCNGMGIPVGKLALYTA 172 >L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)-dependent, cytosolic protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)-dependent, cytosolic protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)-dependent, cytosolic protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)-dependent, cytosolic protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1 variant protein. Length = 572 Score = 128 bits (309), Expect = 2e-29 Identities = 55/85 (64%), Positives = 69/85 (81%) Frame = +3 Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431 +Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+ Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130 Query: 432 GHVYDVLKNWPETDVRAIVVTDGER 506 GH+ VL WPE ++AIVVTDGER Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/36 (63%), Positives = 28/36 (77%) Frame = +1 Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207 ++P LNK +AFT+EERQ L IHGLLPP +QE QV Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55 Score = 46.0 bits (104), Expect = 1e-04 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 509 LGLGDLGACGMGIPVGKLALYTA 577 LGLGDLG GMGIPVGKLALYTA Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTA 179 >AB045122-1|BAB40980.1| 44|Homo sapiens ME2 protein. Length = 44 Score = 48.8 bits (111), Expect = 2e-05 Identities = 20/43 (46%), Positives = 32/43 (74%) Frame = +1 Query: 121 GMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249 GMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL Sbjct: 1 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPL 43 >AF218002-1|AAG17244.1| 554|Homo sapiens unknown protein. Length = 554 Score = 29.9 bits (64), Expect = 8.7 Identities = 21/67 (31%), Positives = 30/67 (44%) Frame = -3 Query: 577 RGVEREFAHRDAHPAGAQIAQAQIRSPSVTTMARTSVSGQFLRTSYTCPLSWIVMKRPLG 398 R E A R AHP GA + SP SV G++ S + P W++ +R L Sbjct: 422 RAAEGGCAERGAHPTGASV-----ESPK---QGVASVPGEWPAASPSTPGEWLLHQRTLW 473 Query: 397 RRYTSPN 377 + + PN Sbjct: 474 GQESEPN 480 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 115,840,093 Number of Sequences: 237096 Number of extensions: 2923688 Number of successful extensions: 16250 Number of sequences better than 10.0: 16 Number of HSP's better than 10.0 without gapping: 15582 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 16244 length of database: 76,859,062 effective HSP length: 87 effective length of database: 56,231,710 effective search space used: 7647512560 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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