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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ce--0218
         (615 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Y14486-1|CAB54839.1|  310|Homo sapiens cytosolic serine hydroxym...    54   5e-07
Y14485-1|CAB54838.1|  483|Homo sapiens cytosolic serine hydroxym...    54   5e-07
L23928-3|AAA36019.1|  403|Homo sapiens serine hydroxymethyltrans...    54   5e-07
L23928-2|AAA36018.1|  444|Homo sapiens serine hydroxymethyltrans...    54   5e-07
L23928-1|AAA36020.1|  483|Homo sapiens serine hydroxymethyltrans...    54   5e-07
L11931-1|AAA63257.1|  483|Homo sapiens serine hydroxymethyltrans...    54   5e-07
BC038598-1|AAH38598.1|  483|Homo sapiens serine hydroxymethyltra...    54   5e-07
BC022874-1|AAH22874.1|  444|Homo sapiens serine hydroxymethyltra...    54   5e-07
BC007979-1|AAH07979.1|  483|Homo sapiens serine hydroxymethyltra...    54   5e-07
AK223552-1|BAD97272.1|  483|Homo sapiens serine hydroxymethyltra...    54   5e-07
U23143-1|AAA64572.1|  483|Homo sapiens mitochondrial serine hydr...    43   0.001
L11932-1|AAA63258.1|  474|Homo sapiens serine hydroxymethyltrans...    43   0.001
BT006866-1|AAP35512.1|  504|Homo sapiens serine hydroxymethyltra...    43   0.001
BC091501-1|AAH91501.1|  480|Homo sapiens SHMT2 protein protein.        43   0.001
BC044211-1|AAH44211.1|  504|Homo sapiens serine hydroxymethyltra...    43   0.001
BC032584-1|AAH32584.1|  494|Homo sapiens SHMT2 protein protein.        43   0.001
BC013677-1|AAH13677.1|  504|Homo sapiens serine hydroxymethyltra...    43   0.001
BC011911-1|AAH11911.1|  504|Homo sapiens serine hydroxymethyltra...    43   0.001
AK223555-1|BAD97275.1|  504|Homo sapiens serine hydroxymethyltra...    43   0.001
L36936-1|AAA57257.1|  230|Homo sapiens metase protein.                 29   9.9  
L23134-1|AAA59582.1|  257|Homo sapiens metase protein.                 29   9.9  
BC025701-1|AAH25701.1|  257|Homo sapiens granzyme M (lymphocyte ...    29   9.9  

>Y14486-1|CAB54839.1|  310|Homo sapiens cytosolic serine
           hydroxymethyltransferase protein.
          Length = 310

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 204 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 255


>Y14485-1|CAB54838.1|  483|Homo sapiens cytosolic serine
           hydroxymethyltransferase protein.
          Length = 483

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 428


>L23928-3|AAA36019.1|  403|Homo sapiens serine
           hydroxymethyltransferase protein.
          Length = 403

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 297 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 348


>L23928-2|AAA36018.1|  444|Homo sapiens serine
           hydroxymethyltransferase protein.
          Length = 444

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 338 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 389


>L23928-1|AAA36020.1|  483|Homo sapiens serine
           hydroxymethyltransferase protein.
          Length = 483

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 428


>L11931-1|AAA63257.1|  483|Homo sapiens serine
           hydroxymethyltransferase protein.
          Length = 483

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 428


>BC038598-1|AAH38598.1|  483|Homo sapiens serine
           hydroxymethyltransferase 1 (soluble) protein.
          Length = 483

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 428


>BC022874-1|AAH22874.1|  444|Homo sapiens serine
           hydroxymethyltransferase 1 (soluble) protein.
          Length = 444

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 338 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 389


>BC007979-1|AAH07979.1|  483|Homo sapiens serine
           hydroxymethyltransferase 1 (soluble) protein.
          Length = 483

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 428


>AK223552-1|BAD97272.1|  483|Homo sapiens serine
           hydroxymethyltransferase 1 (soluble) isoform 1 variant
           protein.
          Length = 483

 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLGQFSSLTL*RLRQTERVISAHQIAKG 307
           LE CS+ACNKNT PGD SAL PSG+RLG   +LT   L + +    AH I +G
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGT-PALTSRGLLEKDFQKVAHFIHRG 428


>U23143-1|AAA64572.1|  483|Homo sapiens mitochondrial serine
           hydroxymethyltransferase protein.
          Length = 483

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 379 LELVSITANKNTCPGDRSAITPGGLRLG 406


>L11932-1|AAA63258.1|  474|Homo sapiens serine
           hydroxymethyltransferase protein.
          Length = 474

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 370 LELVSITANKNTCPGDRSAITPGGLRLG 397


>BT006866-1|AAP35512.1|  504|Homo sapiens serine
           hydroxymethyltransferase 2 (mitochondrial) protein.
          Length = 504

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 400 LELVSITANKNTCPGDRSAITPGGLRLG 427


>BC091501-1|AAH91501.1|  480|Homo sapiens SHMT2 protein protein.
          Length = 480

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 376 LELVSITANKNTCPGDRSAITPGGLRLG 403


>BC044211-1|AAH44211.1|  504|Homo sapiens serine
           hydroxymethyltransferase 2 (mitochondrial) protein.
          Length = 504

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 400 LELVSITANKNTCPGDRSAITPGGLRLG 427


>BC032584-1|AAH32584.1|  494|Homo sapiens SHMT2 protein protein.
          Length = 494

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 390 LELVSITANKNTCPGDRSAITPGGLRLG 417


>BC013677-1|AAH13677.1|  504|Homo sapiens serine
           hydroxymethyltransferase 2 (mitochondrial) protein.
          Length = 504

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 400 LELVSITANKNTCPGDRSAITPGGLRLG 427


>BC011911-1|AAH11911.1|  504|Homo sapiens serine
           hydroxymethyltransferase 2 (mitochondrial) protein.
          Length = 504

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 400 LELVSITANKNTCPGDRSAITPGGLRLG 427


>AK223555-1|BAD97275.1|  504|Homo sapiens serine
           hydroxymethyltransferase 2 (mitochondrial) variant
           protein.
          Length = 504

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 465 LELCSVACNKNTVPGDISALNPSGIRLG 382
           LEL S+  NKNT PGD SA+ P G+RLG
Sbjct: 400 LELVSITANKNTCPGDRSAITPGGLRLG 427


>L36936-1|AAA57257.1|  230|Homo sapiens metase protein.
          Length = 230

 Score = 29.5 bits (63), Expect = 9.9
 Identities = 14/28 (50%), Positives = 17/28 (60%)
 Frame = +2

Query: 398 LGLSALMSPGTVFLLQATLQSSRGGPVP 481
           LGL  L SPG  F ++A +Q  R  PVP
Sbjct: 60  LGLHTLDSPGLTFHIKAAIQHPRYKPVP 87


>L23134-1|AAA59582.1|  257|Homo sapiens metase protein.
          Length = 257

 Score = 29.5 bits (63), Expect = 9.9
 Identities = 14/28 (50%), Positives = 17/28 (60%)
 Frame = +2

Query: 398 LGLSALMSPGTVFLLQATLQSSRGGPVP 481
           LGL  L SPG  F ++A +Q  R  PVP
Sbjct: 79  LGLHTLDSPGLTFHIKAAIQHPRYKPVP 106


>BC025701-1|AAH25701.1|  257|Homo sapiens granzyme M (lymphocyte
           met-ase 1) protein.
          Length = 257

 Score = 29.5 bits (63), Expect = 9.9
 Identities = 14/28 (50%), Positives = 17/28 (60%)
 Frame = +2

Query: 398 LGLSALMSPGTVFLLQATLQSSRGGPVP 481
           LGL  L SPG  F ++A +Q  R  PVP
Sbjct: 79  LGLHTLDSPGLTFHIKAAIQHPRYKPVP 106


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,707,995
Number of Sequences: 237096
Number of extensions: 1633410
Number of successful extensions: 6577
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 6514
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6576
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6579110070
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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