Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ce--0187
(633 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7QDV6 Cluster: ENSANGP00000024916; n=3; Endopterygota|... 69 9e-11
UniRef50_Q9VVX3 Cluster: Frizzled-2 precursor; n=3; Diptera|Rep:... 66 5e-10
UniRef50_UPI00015B43E3 Cluster: PREDICTED: similar to GA21999-PA... 64 2e-09
UniRef50_UPI00005A004E Cluster: PREDICTED: similar to Frizzled 8... 64 2e-09
UniRef50_Q9H461 Cluster: Frizzled-8 precursor; n=10; Theria|Rep:... 64 2e-09
UniRef50_Q13467 Cluster: Frizzled-5 precursor; n=38; Eumetazoa|R... 62 1e-08
UniRef50_UPI000065D9D0 Cluster: Frizzled-5 precursor (Fz-5) (hFz... 60 6e-08
UniRef50_Q3LTR6 Cluster: Frizzled homolog; n=3; Caenorhabditis|R... 60 6e-08
UniRef50_UPI0000F1E04C Cluster: PREDICTED: similar to Frizzled X... 58 2e-07
UniRef50_O00144 Cluster: Frizzled-9 precursor; n=56; Euteleostom... 56 9e-07
UniRef50_Q4SDD9 Cluster: Chromosome 3 SCAF14639, whole genome sh... 54 2e-06
UniRef50_Q5TPW4 Cluster: ENSANGP00000027735; n=1; Anopheles gamb... 54 2e-06
UniRef50_Q9UP38 Cluster: Frizzled-1 precursor; n=86; Eumetazoa|R... 54 4e-06
UniRef50_Q9I9M5 Cluster: Frizzled-1 precursor; n=14; Eumetazoa|R... 53 7e-06
UniRef50_Q4S970 Cluster: Chromosome 3 SCAF14700, whole genome sh... 52 9e-06
UniRef50_O16147 Cluster: Mom-5 protein; n=2; Caenorhabditis|Rep:... 52 1e-05
UniRef50_A7SCF4 Cluster: Predicted protein; n=1; Nematostella ve... 52 1e-05
UniRef50_Q4H315 Cluster: Frizzled receptor; n=1; Ciona intestina... 51 3e-05
UniRef50_Q16JZ8 Cluster: Putative uncharacterized protein; n=2; ... 50 4e-05
UniRef50_Q589S5 Cluster: Frizzled receptor; n=1; Dugesia japonic... 50 5e-05
UniRef50_Q9ULV1 Cluster: Frizzled-4 precursor; n=22; Euteleostom... 50 6e-05
UniRef50_P18537 Cluster: Frizzled precursor; n=9; Diptera|Rep: F... 49 1e-04
UniRef50_Q9N532 Cluster: Abnormal cell migration protein 1, isof... 48 2e-04
UniRef50_UPI0000E495F0 Cluster: PREDICTED: similar to Frizzled-1... 47 3e-04
UniRef50_UPI000065F60A Cluster: Homolog of Gallus gallus "Frizzl... 47 3e-04
UniRef50_Q9PT62 Cluster: Frizzled-4 precursor; n=10; Eumetazoa|R... 47 3e-04
UniRef50_Q16Z40 Cluster: Frizzled; n=2; Culicidae|Rep: Frizzled ... 47 4e-04
UniRef50_UPI0000E46D3A Cluster: PREDICTED: similar to Frzb-1; n=... 46 6e-04
UniRef50_UPI0000D56D61 Cluster: PREDICTED: similar to Frizzled 4... 46 0.001
UniRef50_UPI00015B5F46 Cluster: PREDICTED: hypothetical protein;... 45 0.002
UniRef50_Q3LAK2 Cluster: Frizzled receptor; n=3; Hydroida|Rep: F... 44 0.003
UniRef50_O77438 Cluster: Frizzled-3 precursor; n=3; Sophophora|R... 44 0.004
UniRef50_Q9NL45 Cluster: Frizzled homolog; n=2; Ciona intestinal... 43 0.005
UniRef50_Q4H3F9 Cluster: Frizzled receptor; n=1; Ciona intestina... 43 0.007
UniRef50_Q9NBW1 Cluster: Frizzled-4 precursor; n=3; Sophophora|R... 43 0.007
UniRef50_UPI000065ECB7 Cluster: Frizzled-3 precursor (Fz-3) (hFz... 42 0.016
UniRef50_A7RPM4 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.028
UniRef50_Q95P13 Cluster: Secreted frizzled-related protein precu... 40 0.066
UniRef50_Q4RYT0 Cluster: Chromosome 16 SCAF14974, whole genome s... 39 0.087
UniRef50_O60353 Cluster: Frizzled-6 precursor; n=54; Euteleostom... 39 0.087
UniRef50_A1IKD6 Cluster: Frizzled5/8; n=1; Hydra magnipapillata|... 39 0.11
UniRef50_UPI0000F2D00C Cluster: PREDICTED: hypothetical protein;... 38 0.15
UniRef50_UPI000065D8E2 Cluster: Frizzled-3 precursor (Fz-3) (hFz... 37 0.35
UniRef50_Q4H3G0 Cluster: Frizzled receptor; n=2; Ciona|Rep: Friz... 37 0.35
UniRef50_Q6FHJ7 Cluster: Secreted frizzled-related protein 4 pre... 37 0.46
UniRef50_UPI00004D1D0E Cluster: Membrane frizzled-related protei... 36 0.81
UniRef50_Q5VKN1 Cluster: Frizzled-8; n=2; Elopocephala|Rep: Friz... 36 0.81
UniRef50_UPI0000D9C447 Cluster: PREDICTED: similar to secreted f... 36 1.1
UniRef50_Q5T4F7 Cluster: Secreted frizzled-related protein 5 pre... 36 1.1
UniRef50_Q92765 Cluster: Secreted frizzled-related protein 3 pre... 36 1.1
UniRef50_Q94132 Cluster: Transmembrane receptor LIN-17; n=3; Cae... 35 1.9
UniRef50_Q5J0Z5 Cluster: LIN-17; n=1; Pristionchus pacificus|Rep... 35 1.9
UniRef50_Q4H2U2 Cluster: Secreted frizzled-related protein; n=1;... 35 1.9
UniRef50_Q9W3H0 Cluster: CG1632-PA; n=5; Diptera|Rep: CG1632-PA ... 34 2.5
UniRef50_Q4H2U5 Cluster: Secreted frizzled-related protein; n=1;... 34 2.5
UniRef50_A0CYS2 Cluster: Chromosome undetermined scaffold_31, wh... 34 2.5
UniRef50_UPI0000E48FF8 Cluster: PREDICTED: similar to fibropelli... 34 3.3
UniRef50_UPI00015B523C Cluster: PREDICTED: similar to conserved ... 33 5.7
UniRef50_Q552K5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_Q23FE7 Cluster: Putative uncharacterized protein; n=2; ... 33 5.7
UniRef50_Q16VN8 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_A2DV64 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_Q0IHH5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.5
UniRef50_A6MT14 Cluster: Frizzled 4; n=7; mojavensis species com... 33 7.5
UniRef50_Q9BY79 Cluster: Membrane frizzled-related protein; n=15... 33 7.5
UniRef50_Q61089 Cluster: Frizzled-6 precursor; n=21; Euteleostom... 33 7.5
>UniRef50_Q7QDV6 Cluster: ENSANGP00000024916; n=3;
Endopterygota|Rep: ENSANGP00000024916 - Anopheles
gambiae str. PEST
Length = 687
Score = 68.9 bits (161), Expect = 9e-11
Identities = 31/65 (47%), Positives = 39/65 (60%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC++ITIPMCRGIGYNLTSFPN ++ +++ P LCS+YT
Sbjct: 65 RCEEITIPMCRGIGYNLTSFPNEMNHETQEEAGLEVHQFWPLVEIKCSPDLKFFLCSMYT 124
Query: 613 PICIE 627
PICIE
Sbjct: 125 PICIE 129
Score = 63.7 bits (148), Expect = 4e-09
Identities = 27/35 (77%), Positives = 29/35 (82%)
Frame = +3
Query: 492 PQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
P +TQEEAGLEVHQ+WPLVEIKCS DLKFFL
Sbjct: 85 PNEMNHETQEEAGLEVHQFWPLVEIKCSPDLKFFL 119
>UniRef50_Q9VVX3 Cluster: Frizzled-2 precursor; n=3; Diptera|Rep:
Frizzled-2 precursor - Drosophila melanogaster (Fruit
fly)
Length = 694
Score = 66.5 bits (155), Expect = 5e-10
Identities = 29/65 (44%), Positives = 38/65 (58%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC++ITIPMCRGIGYN+TSFPN ++ + + P LCS+YT
Sbjct: 63 RCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYT 122
Query: 613 PICIE 627
PIC+E
Sbjct: 123 PICLE 127
Score = 62.5 bits (145), Expect = 8e-09
Identities = 26/35 (74%), Positives = 29/35 (82%)
Frame = +3
Query: 492 PQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
P +TQ+EAGLEVHQ+WPLVEIKCS DLKFFL
Sbjct: 83 PNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFL 117
>UniRef50_UPI00015B43E3 Cluster: PREDICTED: similar to GA21999-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA21999-PA - Nasonia vitripennis
Length = 641
Score = 64.5 bits (150), Expect = 2e-09
Identities = 27/36 (75%), Positives = 30/36 (83%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P DTQ+EAGLEVHQ+WPLVEIKCS DLKFFL
Sbjct: 78 MPNELNHDTQDEAGLEVHQFWPLVEIKCSLDLKFFL 113
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/64 (42%), Positives = 36/64 (56%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC++ITIPMC+GIGYNLT+ PN L+ + + P LCS+YT
Sbjct: 59 RCEEITIPMCKGIGYNLTTMPNELNHDTQDEAGLEVHQFWPLVEIKCSLDLKFFLCSMYT 118
Query: 613 PICI 624
PIC+
Sbjct: 119 PICL 122
>UniRef50_UPI00005A004E Cluster: PREDICTED: similar to Frizzled 8
precursor (Frizzled-8) (Fz-8) (mFz8); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Frizzled 8
precursor (Frizzled-8) (Fz-8) (mFz8) - Canis familiaris
Length = 613
Score = 64.5 bits (150), Expect = 2e-09
Identities = 26/37 (70%), Positives = 32/37 (86%)
Frame = +3
Query: 486 FLPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
++P + DTQ+EAGLEVHQ+WPLVEI+CS DLKFFL
Sbjct: 160 YMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFL 196
Score = 56.0 bits (129), Expect = 7e-07
Identities = 24/64 (37%), Positives = 33/64 (51%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ+IT+P+C+GIGYN T PN + + + P LCS+YTP
Sbjct: 143 CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTP 202
Query: 616 ICIE 627
IC+E
Sbjct: 203 ICLE 206
>UniRef50_Q9H461 Cluster: Frizzled-8 precursor; n=10; Theria|Rep:
Frizzled-8 precursor - Homo sapiens (Human)
Length = 694
Score = 64.5 bits (150), Expect = 2e-09
Identities = 26/37 (70%), Positives = 32/37 (86%)
Frame = +3
Query: 486 FLPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
++P + DTQ+EAGLEVHQ+WPLVEI+CS DLKFFL
Sbjct: 52 YMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFL 88
Score = 56.0 bits (129), Expect = 7e-07
Identities = 24/64 (37%), Positives = 33/64 (51%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ+IT+P+C+GIGYN T PN + + + P LCS+YTP
Sbjct: 35 CQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTP 94
Query: 616 ICIE 627
IC+E
Sbjct: 95 ICLE 98
>UniRef50_Q13467 Cluster: Frizzled-5 precursor; n=38; Eumetazoa|Rep:
Frizzled-5 precursor - Homo sapiens (Human)
Length = 585
Score = 62.1 bits (144), Expect = 1e-08
Identities = 25/36 (69%), Positives = 31/36 (86%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P + DTQ+EAGLEVHQ+WPLVEI+CS DL+FFL
Sbjct: 51 MPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFL 86
Score = 60.5 bits (140), Expect = 3e-08
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 430 PRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVY 609
P CQ+IT+PMCRGIGYNLT PN + + + P LCS+Y
Sbjct: 31 PVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMY 90
Query: 610 TPICI 624
TPIC+
Sbjct: 91 TPICL 95
>UniRef50_UPI000065D9D0 Cluster: Frizzled-5 precursor (Fz-5) (hFz5)
(FzE5).; n=2; Euteleostomi|Rep: Frizzled-5 precursor
(Fz-5) (hFz5) (FzE5). - Takifugu rubripes
Length = 422
Score = 59.7 bits (138), Expect = 6e-08
Identities = 24/37 (64%), Positives = 29/37 (78%)
Frame = +3
Query: 486 FLPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
++P + DTQEE GLEVHQ+WPLV I+CS DL FFL
Sbjct: 18 YMPNQFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFL 54
Score = 52.4 bits (120), Expect = 9e-06
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ IT+PMC+ IGYNLT PN + +++ P LCS+YTP
Sbjct: 1 CEPITVPMCKDIGYNLTYMPNQFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTP 60
Query: 616 ICI 624
IC+
Sbjct: 61 ICL 63
>UniRef50_Q3LTR6 Cluster: Frizzled homolog; n=3; Caenorhabditis|Rep:
Frizzled homolog - Caenorhabditis elegans
Length = 578
Score = 59.7 bits (138), Expect = 6e-08
Identities = 25/68 (36%), Positives = 39/68 (57%)
Frame = +1
Query: 424 QQPRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCS 603
++ +C+ ITIP+C+GIGYN+TSFPN+ ++++ P LC+
Sbjct: 21 KRQKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCT 80
Query: 604 VYTPICIE 627
+YTPIC E
Sbjct: 81 MYTPICQE 88
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/35 (62%), Positives = 26/35 (74%)
Frame = +3
Query: 492 PQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
P G + QEEAGLEVHQ++PLVE+ C LKFFL
Sbjct: 44 PNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFL 78
>UniRef50_UPI0000F1E04C Cluster: PREDICTED: similar to Frizzled X
isoform 1; n=3; Euteleostomi|Rep: PREDICTED: similar to
Frizzled X isoform 1 - Danio rerio
Length = 561
Score = 58.0 bits (134), Expect = 2e-07
Identities = 24/65 (36%), Positives = 35/65 (53%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C+ ITIPMC+GIGYN+T PN L+ +++ + P LCS+Y
Sbjct: 35 KCEPITIPMCQGIGYNMTRMPNLLNYESQEEASIKLNEFAPLVKYGCDIHLQFFLCSLYV 94
Query: 613 PICIE 627
P+C E
Sbjct: 95 PMCAE 99
>UniRef50_O00144 Cluster: Frizzled-9 precursor; n=56;
Euteleostomi|Rep: Frizzled-9 precursor - Homo sapiens
(Human)
Length = 591
Score = 55.6 bits (128), Expect = 9e-07
Identities = 25/64 (39%), Positives = 31/64 (48%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ + IPMCRGIGYNLT PN L T + + P LCS+Y P
Sbjct: 39 CQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAP 98
Query: 616 ICIE 627
+C +
Sbjct: 99 MCTD 102
>UniRef50_Q4SDD9 Cluster: Chromosome 3 SCAF14639, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14639, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 459
Score = 54.4 bits (125), Expect = 2e-06
Identities = 22/36 (61%), Positives = 30/36 (83%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P G Q+EAGLEVHQ++PLVE++CSS+L+FFL
Sbjct: 27 MPNLLGHRGQDEAGLEVHQFYPLVEVRCSSELRFFL 62
Score = 41.1 bits (92), Expect = 0.022
Identities = 20/62 (32%), Positives = 26/62 (41%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ I+IP+C I YN T PN L + + P LCS+Y P
Sbjct: 9 CQPISIPLCTHIAYNQTIMPNLLGHRGQDEAGLEVHQFYPLVEVRCSSELRFFLCSLYAP 68
Query: 616 IC 621
+C
Sbjct: 69 VC 70
>UniRef50_Q5TPW4 Cluster: ENSANGP00000027735; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000027735 - Anopheles gambiae
str. PEST
Length = 254
Score = 54.4 bits (125), Expect = 2e-06
Identities = 25/38 (65%), Positives = 28/38 (73%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFLVL 602
+P R G Q+EA LEVHQY PLV+I CS DLKFFL L
Sbjct: 58 MPNRFGHTKQDEAALEVHQYVPLVKIDCSPDLKFFLCL 95
Score = 43.6 bits (98), Expect = 0.004
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC+ ITIP C GI YN T PN T++ + P LC +Y
Sbjct: 39 RCEPITIPFCIGIPYNRTIMPNRFGHTKQDEAALEVHQYVPLVKIDCSPDLKFFLCLLYA 98
Query: 613 PIC 621
P+C
Sbjct: 99 PVC 101
>UniRef50_Q9UP38 Cluster: Frizzled-1 precursor; n=86; Eumetazoa|Rep:
Frizzled-1 precursor - Homo sapiens (Human)
Length = 647
Score = 53.6 bits (123), Expect = 4e-06
Identities = 21/36 (58%), Positives = 30/36 (83%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P G QE+AGLEVHQ++PLV+++CS++LKFFL
Sbjct: 134 MPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFL 169
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/62 (33%), Positives = 27/62 (43%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ I+IP+C I YN T PN L T ++ P LCS+Y P
Sbjct: 116 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAP 175
Query: 616 IC 621
+C
Sbjct: 176 VC 177
>UniRef50_Q9I9M5 Cluster: Frizzled-1 precursor; n=14; Eumetazoa|Rep:
Frizzled-1 precursor - Xenopus laevis (African clawed
frog)
Length = 559
Score = 52.8 bits (121), Expect = 7e-06
Identities = 21/36 (58%), Positives = 29/36 (80%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P G QE+AGLEVHQ++PLV+++CS +LKFFL
Sbjct: 69 MPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELKFFL 104
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/62 (33%), Positives = 27/62 (43%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ I+IP+C I YN T PN L T ++ P LCS+Y P
Sbjct: 51 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELKFFLCSIYAP 110
Query: 616 IC 621
+C
Sbjct: 111 VC 112
>UniRef50_Q4S970 Cluster: Chromosome 3 SCAF14700, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14700, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 456
Score = 52.4 bits (120), Expect = 9e-06
Identities = 21/36 (58%), Positives = 29/36 (80%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P G QE+AGLEVHQ++PLV+++CS +LKFFL
Sbjct: 53 MPNLVGHYNQEDAGLEVHQFYPLVKVQCSPELKFFL 88
Score = 42.7 bits (96), Expect = 0.007
Identities = 20/62 (32%), Positives = 26/62 (41%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ ITIP+C I YN T PN + ++ P LCS+Y P
Sbjct: 35 CQQITIPLCTDIAYNQTIMPNLVGHYNQEDAGLEVHQFYPLVKVQCSPELKFFLCSMYAP 94
Query: 616 IC 621
+C
Sbjct: 95 VC 96
>UniRef50_O16147 Cluster: Mom-5 protein; n=2; Caenorhabditis|Rep:
Mom-5 protein - Caenorhabditis elegans
Length = 568
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/63 (34%), Positives = 30/63 (47%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C+ ITIPMC+ + YN T FPN L T + + P LC+VY
Sbjct: 36 KCEHITIPMCKNLDYNQTVFPNLLGHTTQSEAGPAIAQFNPLIKVKCSEDIRLFLCTVYA 95
Query: 613 PIC 621
P+C
Sbjct: 96 PVC 98
>UniRef50_A7SCF4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 603
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/63 (38%), Positives = 31/63 (49%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C ITIP+C GIGYN T FPN L +++ R P LCSV+
Sbjct: 31 KCTPITIPLCMGIGYNATRFPNFLAQESQEEAAKRIHEFKPLIAVNCAPLLRFFLCSVFV 90
Query: 613 PIC 621
P+C
Sbjct: 91 PMC 93
>UniRef50_Q4H315 Cluster: Frizzled receptor; n=1; Ciona
intestinalis|Rep: Frizzled receptor - Ciona intestinalis
(Transparent sea squirt)
Length = 581
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C+ IT+ +C+GI YN+T FPN L + + + P LCSVYT
Sbjct: 30 KCEPITLSICKGIQYNVTIFPNILGHQDQSEAGLQLNQFYPLVKVGCSPTLQLFLCSVYT 89
Query: 613 PIC 621
PIC
Sbjct: 90 PIC 92
Score = 39.1 bits (87), Expect = 0.087
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +3
Query: 492 PQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
P G Q EAGL+++Q++PLV++ CS L+ FL
Sbjct: 50 PNILGHQDQSEAGLQLNQFYPLVKVGCSPTLQLFL 84
>UniRef50_Q16JZ8 Cluster: Putative uncharacterized protein; n=2;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 276
Score = 50.4 bits (115), Expect = 4e-05
Identities = 23/36 (63%), Positives = 26/36 (72%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P G QEEA LEVHQ+ PLV+I CS DLKFFL
Sbjct: 66 MPNLIGHTKQEEAALEVHQFIPLVKIDCSPDLKFFL 101
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/63 (31%), Positives = 29/63 (46%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC+ ITIP C I YN T PN + T++++ P LC++Y
Sbjct: 47 RCETITIPFCTDIQYNRTIMPNLIGHTKQEEAALEVHQFIPLVKIDCSPDLKFFLCTLYA 106
Query: 613 PIC 621
P+C
Sbjct: 107 PVC 109
>UniRef50_Q589S5 Cluster: Frizzled receptor; n=1; Dugesia
japonica|Rep: Frizzled receptor - Dugesia japonica
(Planarian)
Length = 722
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/65 (32%), Positives = 33/65 (50%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC+D+ +P+CRG+ YN T PN + +++ + LCS+YT
Sbjct: 35 RCEDLVMPLCRGLWYNRTRMPNMFNHETQEEAGHQAQQFMYLVTIKCSPDLHFFLCSIYT 94
Query: 613 PICIE 627
PIC+E
Sbjct: 95 PICVE 99
Score = 41.1 bits (92), Expect = 0.022
Identities = 19/36 (52%), Positives = 23/36 (63%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P +TQEEAG + Q+ LV IKCS DL FFL
Sbjct: 54 MPNMFNHETQEEAGHQAQQFMYLVTIKCSPDLHFFL 89
>UniRef50_Q9ULV1 Cluster: Frizzled-4 precursor; n=22;
Euteleostomi|Rep: Frizzled-4 precursor - Homo sapiens
(Human)
Length = 537
Score = 49.6 bits (113), Expect = 6e-05
Identities = 22/68 (32%), Positives = 32/68 (47%)
Frame = +1
Query: 424 QQPRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCS 603
++ RC I I MC+ +GYN+T PN + + + + T P LCS
Sbjct: 41 EERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCS 100
Query: 604 VYTPICIE 627
VY P+C E
Sbjct: 101 VYVPMCTE 108
>UniRef50_P18537 Cluster: Frizzled precursor; n=9; Diptera|Rep:
Frizzled precursor - Drosophila melanogaster (Fruit fly)
Length = 581
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P G QEEAGLEVHQ+ PLV+I CS DL+ FL
Sbjct: 71 MPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFL 106
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/63 (31%), Positives = 31/63 (49%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC+ ITI +C+ I YN+T PN + T++++ P LCS+Y
Sbjct: 52 RCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYV 111
Query: 613 PIC 621
P+C
Sbjct: 112 PVC 114
>UniRef50_Q9N532 Cluster: Abnormal cell migration protein 1, isoform
b; n=3; Caenorhabditis|Rep: Abnormal cell migration
protein 1, isoform b - Caenorhabditis elegans
Length = 529
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/67 (37%), Positives = 29/67 (43%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RCQ + MC + YNLTSFPN +D K P LCSVY
Sbjct: 25 RCQKVDHEMCNDLPYNLTSFPNLVDEESWKDASESILTYKPLLSVVCSEQLKFFLCSVYF 84
Query: 613 PICIEGL 633
P+C E L
Sbjct: 85 PMCNEKL 91
>UniRef50_UPI0000E495F0 Cluster: PREDICTED: similar to Frizzled-10;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Frizzled-10 - Strongylocentrotus purpuratus
Length = 610
Score = 47.2 bits (107), Expect = 3e-04
Identities = 22/67 (32%), Positives = 29/67 (43%)
Frame = +1
Query: 427 QPRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSV 606
Q C+ ITI C+GIGYN+T PN + + P LCS+
Sbjct: 31 QGHCERITIDFCQGIGYNMTKMPNLFGHVTQSEAAPSIHEFHPLVVVGCAEHLRLFLCSM 90
Query: 607 YTPICIE 627
Y P+C E
Sbjct: 91 YAPMCSE 97
>UniRef50_UPI000065F60A Cluster: Homolog of Gallus gallus "Frizzled
1 precursor (Frizzled-1) (Fz-1) (cFz-1).; n=1; Takifugu
rubripes|Rep: Homolog of Gallus gallus "Frizzled 1
precursor (Frizzled-1) (Fz-1) (cFz-1). - Takifugu
rubripes
Length = 582
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/65 (32%), Positives = 32/65 (49%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ IT+P+C+G+ YN T PN L T +++ + + LC VY P
Sbjct: 380 CEPITVPLCQGLPYNQTITPNLLGHTSQREAMMKMSFFNGIVQTVCSEDIRLFLCMVYVP 439
Query: 616 ICIEG 630
C+EG
Sbjct: 440 RCVEG 444
Score = 45.6 bits (103), Expect = 0.001
Identities = 19/36 (52%), Positives = 27/36 (75%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
LP G TQEEAGL++HQ+ PL+++ CS+ L+ FL
Sbjct: 280 LPNILGHRTQEEAGLQMHQFVPLIKVDCSAHLRTFL 315
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/65 (33%), Positives = 26/65 (40%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ ITIP C+ + Y T PN L + P LCSVYTP
Sbjct: 144 CQAITIPFCKDLPYTHTILPNILGHKNQDDASLEVHTFAPLIHAGCSPDMKPFLCSVYTP 203
Query: 616 ICIEG 630
C+ G
Sbjct: 204 ECVLG 208
Score = 39.9 bits (89), Expect = 0.050
Identities = 19/65 (29%), Positives = 27/65 (41%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ IT+ +C + Y T PN L +++ + P LCS YTP
Sbjct: 262 CQPITLSLCNDLPYTETILPNILGHRTQEEAGLQMHQFVPLIKVDCSAHLRTFLCSAYTP 321
Query: 616 ICIEG 630
C+ G
Sbjct: 322 KCVSG 326
Score = 38.3 bits (85), Expect = 0.15
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
LP G Q++A LEVH + PL+ CS D+K FL
Sbjct: 162 LPNILGHKNQDDASLEVHTFAPLIHAGCSPDMKPFL 197
>UniRef50_Q9PT62 Cluster: Frizzled-4 precursor; n=10; Eumetazoa|Rep:
Frizzled-4 precursor - Xenopus laevis (African clawed
frog)
Length = 523
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/68 (30%), Positives = 31/68 (45%)
Frame = +1
Query: 424 QQPRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCS 603
++ C I I MC+ +GYN+T PN + + + + T P LCS
Sbjct: 27 EERSCDPIRITMCQNLGYNVTKMPNLVGHELQADAELQLTTFTPLIQYGCSSQLQFFLCS 86
Query: 604 VYTPICIE 627
VY P+C E
Sbjct: 87 VYVPMCTE 94
>UniRef50_Q16Z40 Cluster: Frizzled; n=2; Culicidae|Rep: Frizzled -
Aedes aegypti (Yellowfever mosquito)
Length = 582
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +1
Query: 427 QPRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSV 606
Q C+ I I +CRGIGYN TS PN + + D P LC+
Sbjct: 31 QRTCEPIRIELCRGIGYNETSLPNLVGHELQTDADFTLQTFSPLIQYGCSKQLKFFLCAA 90
Query: 607 YTPIC 621
Y P+C
Sbjct: 91 YVPMC 95
>UniRef50_UPI0000E46D3A Cluster: PREDICTED: similar to Frzb-1; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Frzb-1 - Strongylocentrotus purpuratus
Length = 267
Score = 46.4 bits (105), Expect = 6e-04
Identities = 21/68 (30%), Positives = 30/68 (44%)
Frame = +1
Query: 427 QPRCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSV 606
+P CQ + +PMC + YNLT PN L + ++ P LC++
Sbjct: 7 RPECQLVQLPMCESMPYNLTRMPNLLHHSTQENAKLAIEQFLPLVNTNCSGNLTFFLCAM 66
Query: 607 YTPICIEG 630
Y PIC G
Sbjct: 67 YVPICTMG 74
>UniRef50_UPI0000D56D61 Cluster: PREDICTED: similar to Frizzled 4
precursor (Frizzled-4) (Fz-4) (mFz4); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Frizzled 4
precursor (Frizzled-4) (Fz-4) (mFz4) - Tribolium
castaneum
Length = 527
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ I + MC +GYN+T PN +++ D + P LCSVY P
Sbjct: 22 CEPIRVDMCTNLGYNMTEMPNLGGNDIQQEADYTLKSFSPLIQYGCSSQLKLFLCSVYVP 81
Query: 616 ICIE 627
+C E
Sbjct: 82 MCTE 85
>UniRef50_UPI00015B5F46 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 573
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/65 (27%), Positives = 31/65 (47%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C+ + + CRG+ YNLT+ PN + + + + + P LCSV+
Sbjct: 36 KCERLNVSFCRGLRYNLTAMPNFMGHEDQLQAERELAKLMPLVHYNCSRHLRFFLCSVFA 95
Query: 613 PICIE 627
P+C E
Sbjct: 96 PVCSE 100
>UniRef50_Q3LAK2 Cluster: Frizzled receptor; n=3; Hydroida|Rep:
Frizzled receptor - Hydractinia echinata (Snail fur)
(Hermit crab hydroid)
Length = 560
Score = 44.0 bits (99), Expect = 0.003
Identities = 18/57 (31%), Positives = 27/57 (47%)
Frame = +1
Query: 457 MCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTPICIE 627
+C+ +GYN T FPN+L+ + N P LCSVY P+C++
Sbjct: 40 LCQNLGYNATMFPNSLEHRNMENASTELDNFLPLVKIRCAKEIEFFLCSVYLPVCLD 96
>UniRef50_O77438 Cluster: Frizzled-3 precursor; n=3; Sophophora|Rep:
Frizzled-3 precursor - Drosophila melanogaster (Fruit
fly)
Length = 581
Score = 43.6 bits (98), Expect = 0.004
Identities = 18/63 (28%), Positives = 30/63 (47%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+CQ I + C+G+GYN+T+ PN T + + + + + P LCS
Sbjct: 39 QCQPIAVSACQGLGYNMTALPNLAGHTNQLEAELQIAKLVPLIESGCSRRARFLLCSSLF 98
Query: 613 PIC 621
P+C
Sbjct: 99 PLC 101
>UniRef50_Q9NL45 Cluster: Frizzled homolog; n=2; Ciona
intestinalis|Rep: Frizzled homolog - Ciona intestinalis
(Transparent sea squirt)
Length = 872
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPT---RRKKPD*RFTNIGPXXXXXXXXXXXXXLCSV 606
C+ I +PMC IGYN T ++ P+ +K+ GP +CSV
Sbjct: 126 CEPIQVPMCIDIGYNFTDM--SVSPSYIYDQKEAAQSVIQFGPLTKTKCAEEMKLLVCSV 183
Query: 607 YTPICIEG 630
YTPICI G
Sbjct: 184 YTPICIPG 191
>UniRef50_Q4H3F9 Cluster: Frizzled receptor; n=1; Ciona
intestinalis|Rep: Frizzled receptor - Ciona intestinalis
(Transparent sea squirt)
Length = 602
Score = 42.7 bits (96), Expect = 0.007
Identities = 20/67 (29%), Positives = 29/67 (43%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC+ I I MC+G+GYN T PN R+ + + LC+ +
Sbjct: 55 RCEPIQIKMCQGLGYNATRMPNRFGQYRQTEAGIELNSYQVLLQYNCSSELPMFLCAAFL 114
Query: 613 PICIEGL 633
P+C GL
Sbjct: 115 PMCEPGL 121
Score = 37.1 bits (82), Expect = 0.35
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P R G Q EAG+E++ Y L++ CSS+L FL
Sbjct: 74 MPNRFGQYRQTEAGIELNSYQVLLQYNCSSELPMFL 109
>UniRef50_Q9NBW1 Cluster: Frizzled-4 precursor; n=3; Sophophora|Rep:
Frizzled-4 precursor - Drosophila melanogaster (Fruit
fly)
Length = 705
Score = 42.7 bits (96), Expect = 0.007
Identities = 20/63 (31%), Positives = 27/63 (42%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C+ I I MCR IGYN TS PN + + + P LC+ Y
Sbjct: 45 QCETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYV 104
Query: 613 PIC 621
P+C
Sbjct: 105 PMC 107
>UniRef50_UPI000065ECB7 Cluster: Frizzled-3 precursor (Fz-3)
(hFz3).; n=1; Takifugu rubripes|Rep: Frizzled-3
precursor (Fz-3) (hFz3). - Takifugu rubripes
Length = 634
Score = 41.5 bits (93), Expect = 0.016
Identities = 19/64 (29%), Positives = 29/64 (45%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ IT+ MC+G+ YN T PN L+ ++ P LC++Y P
Sbjct: 32 CEPITLRMCQGLPYNATFMPNLLNHYDQQTAALAMEPFHPMVNLQCSPDLRMFLCALYAP 91
Query: 616 ICIE 627
+C E
Sbjct: 92 VCTE 95
>UniRef50_A7RPM4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 260
Score = 40.7 bits (91), Expect = 0.028
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
CQ IT+P C+ + YN+T PN L T +++ + LC + P
Sbjct: 5 CQPITVPACQSLPYNMTRLPNHLGHTSQRQIEHEINEYSQLISANCSADLVFLLCVYHLP 64
Query: 616 IC 621
IC
Sbjct: 65 IC 66
>UniRef50_Q95P13 Cluster: Secreted frizzled-related protein precusor
precursor; n=5; Strongylocentrotus purpuratus|Rep:
Secreted frizzled-related protein precusor precursor -
Strongylocentrotus purpuratus (Purple sea urchin)
Length = 920
Score = 39.5 bits (88), Expect = 0.066
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Frame = +1
Query: 424 QQPR-CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLC 600
Q+P C D+T+P CR +G+ T FPN T ++ T++ +C
Sbjct: 179 QEPELCYDVTVPECRQMGFTHTKFPNIFGHTTPEEMAQDMTSLTGLILSGCSDDLLPLIC 238
Query: 601 SVYTPIC 621
+ Y P C
Sbjct: 239 AAYLPKC 245
Score = 37.5 bits (83), Expect = 0.26
Identities = 16/62 (25%), Positives = 25/62 (40%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ ++ P+C + Y+ T FPN L + + P LC+VY P
Sbjct: 398 CESVSTPICMDMKYDFTQFPNLLQHANQDVAYLELSQFAPLIQVECSLDLGAFLCAVYMP 457
Query: 616 IC 621
C
Sbjct: 458 PC 459
>UniRef50_Q4RYT0 Cluster: Chromosome 16 SCAF14974, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
SCAF14974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 471
Score = 39.1 bits (87), Expect = 0.087
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPN 498
C+ I + MCRG+ YNLTSFPN
Sbjct: 358 CETIEVEMCRGLSYNLTSFPN 378
>UniRef50_O60353 Cluster: Frizzled-6 precursor; n=54;
Euteleostomi|Rep: Frizzled-6 precursor - Homo sapiens
(Human)
Length = 706
Score = 39.1 bits (87), Expect = 0.087
Identities = 18/64 (28%), Positives = 26/64 (40%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ IT+P C + YN+T FPN + + + P LC + P
Sbjct: 24 CEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVP 83
Query: 616 ICIE 627
CIE
Sbjct: 84 TCIE 87
>UniRef50_A1IKD6 Cluster: Frizzled5/8; n=1; Hydra
magnipapillata|Rep: Frizzled5/8 - Hydra magnipapillata
(Hydra)
Length = 525
Score = 38.7 bits (86), Expect = 0.11
Identities = 17/63 (26%), Positives = 26/63 (41%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C+ ++I MC +GYNLT PN + P +CS+Y
Sbjct: 38 KCEKLSITMCEKVGYNLTFMPNKHGHVNQIDAGQLIRQFAPLVAINCSPLLAHFVCSLYA 97
Query: 613 PIC 621
P+C
Sbjct: 98 PMC 100
>UniRef50_UPI0000F2D00C Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 317
Score = 38.3 bits (85), Expect = 0.15
Identities = 13/26 (50%), Positives = 19/26 (73%)
Frame = +1
Query: 427 QPRCQDITIPMCRGIGYNLTSFPNAL 504
+P C+ I + MC+G+ YN T+FPN L
Sbjct: 134 EPACEPIWVEMCQGLSYNSTAFPNTL 159
>UniRef50_UPI000065D8E2 Cluster: Frizzled-3 precursor (Fz-3)
(hFz3).; n=1; Takifugu rubripes|Rep: Frizzled-3
precursor (Fz-3) (hFz3). - Takifugu rubripes
Length = 717
Score = 37.1 bits (82), Expect = 0.35
Identities = 17/63 (26%), Positives = 27/63 (42%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ I + MC+ + YN T PN L ++ P LC++YTP
Sbjct: 9 CEPIRLRMCQDLPYNTTFMPNLLHHYDQQTAALAMEPFHPMVNLECSPDLRMFLCALYTP 68
Query: 616 ICI 624
+C+
Sbjct: 69 VCV 71
>UniRef50_Q4H3G0 Cluster: Frizzled receptor; n=2; Ciona|Rep:
Frizzled receptor - Ciona intestinalis (Transparent sea
squirt)
Length = 810
Score = 37.1 bits (82), Expect = 0.35
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Frame = +1
Query: 430 PRCQDITIPMC--------RGIG--YNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXX 579
P+C+ +T+PMC +GI YN T+FPN + + + + + P
Sbjct: 24 PQCRPVTLPMCLRNNNERNKGIKWIYNETTFPNFNNDASESEVEISLSLLHPLLSTSCSR 83
Query: 580 XXXXXLCSVYTPICIEG 630
LCSV++P C+ G
Sbjct: 84 YLELFLCSVFSPACMGG 100
>UniRef50_Q6FHJ7 Cluster: Secreted frizzled-related protein 4
precursor; n=27; Tetrapoda|Rep: Secreted
frizzled-related protein 4 precursor - Homo sapiens
(Human)
Length = 346
Score = 36.7 bits (81), Expect = 0.46
Identities = 17/62 (27%), Positives = 27/62 (43%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ + IPMCR + +N+T PN L + ++ LC++Y P
Sbjct: 24 CEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAP 83
Query: 616 IC 621
IC
Sbjct: 84 IC 85
Score = 35.9 bits (79), Expect = 0.81
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +3
Query: 489 LPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
+P TQE A L + QY LV++ CS+ L+FFL
Sbjct: 42 MPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFL 77
>UniRef50_UPI00004D1D0E Cluster: Membrane frizzled-related protein
(Membrane-type frizzled-related protein).; n=1; Xenopus
tropicalis|Rep: Membrane frizzled-related protein
(Membrane-type frizzled-related protein). - Xenopus
tropicalis
Length = 435
Score = 35.9 bits (79), Expect = 0.81
Identities = 11/21 (52%), Positives = 17/21 (80%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPN 498
CQ + +PMC+G+ Y+ T+FPN
Sbjct: 322 CQPVQVPMCQGLSYSQTAFPN 342
>UniRef50_Q5VKN1 Cluster: Frizzled-8; n=2; Elopocephala|Rep:
Frizzled-8 - Elops hawaiensis (Hawaiian ladyfish)
Length = 294
Score = 35.9 bits (79), Expect = 0.81
Identities = 14/16 (87%), Positives = 15/16 (93%)
Frame = +3
Query: 549 WPLVEIKCSSDLKFFL 596
WPLVEI+CS DLKFFL
Sbjct: 24 WPLVEIQCSPDLKFFL 39
>UniRef50_UPI0000D9C447 Cluster: PREDICTED: similar to secreted
frizzled-related protein 5; n=2; Catarrhini|Rep:
PREDICTED: similar to secreted frizzled-related protein
5 - Macaca mulatta
Length = 376
Score = 35.5 bits (78), Expect = 1.1
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Frame = +1
Query: 430 PRCQDIT--IPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCS 603
P+C DI +P+C +GY PN L+ + + ++ P LCS
Sbjct: 110 PQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCS 169
Query: 604 VYTPICIE 627
++ P+C++
Sbjct: 170 LFAPVCLD 177
>UniRef50_Q5T4F7 Cluster: Secreted frizzled-related protein 5
precursor; n=60; Euteleostomi|Rep: Secreted
frizzled-related protein 5 precursor - Homo sapiens
(Human)
Length = 317
Score = 35.5 bits (78), Expect = 1.1
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Frame = +1
Query: 430 PRCQDIT--IPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCS 603
P+C DI +P+C +GY PN L+ + + ++ P LCS
Sbjct: 51 PQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCS 110
Query: 604 VYTPICIE 627
++ P+C++
Sbjct: 111 LFAPVCLD 118
>UniRef50_Q92765 Cluster: Secreted frizzled-related protein 3
precursor; n=30; Euteleostomi|Rep: Secreted
frizzled-related protein 3 precursor - Homo sapiens
(Human)
Length = 325
Score = 35.5 bits (78), Expect = 1.1
Identities = 15/62 (24%), Positives = 26/62 (41%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYTP 615
C+ + IP+C+ + +N+T PN L + + LC++Y P
Sbjct: 35 CEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAP 94
Query: 616 IC 621
IC
Sbjct: 95 IC 96
>UniRef50_Q94132 Cluster: Transmembrane receptor LIN-17; n=3;
Caenorhabditis|Rep: Transmembrane receptor LIN-17 -
Caenorhabditis elegans
Length = 558
Score = 34.7 bits (76), Expect = 1.9
Identities = 17/67 (25%), Positives = 28/67 (41%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
+C I I +C+ + YN T FPN + + + P +CSV+
Sbjct: 27 KCIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFA 86
Query: 613 PICIEGL 633
P+C G+
Sbjct: 87 PMCPIGM 93
>UniRef50_Q5J0Z5 Cluster: LIN-17; n=1; Pristionchus pacificus|Rep:
LIN-17 - Pristionchus pacificus
Length = 563
Score = 34.7 bits (76), Expect = 1.9
Identities = 18/63 (28%), Positives = 27/63 (42%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC + MC I YN+T PN + T + + D + P +CSV+
Sbjct: 29 RCVPMQHKMCADIPYNMTYHPNPISATEQSQID----HFNPLIKTKCHPHIKFFVCSVFE 84
Query: 613 PIC 621
P+C
Sbjct: 85 PMC 87
>UniRef50_Q4H2U2 Cluster: Secreted frizzled-related protein; n=1;
Ciona intestinalis|Rep: Secreted frizzled-related
protein - Ciona intestinalis (Transparent sea squirt)
Length = 148
Score = 34.7 bits (76), Expect = 1.9
Identities = 16/39 (41%), Positives = 22/39 (56%)
Frame = +3
Query: 480 PHFLPQRAGPDTQEEAGLEVHQYWPLVEIKCSSDLKFFL 596
P +P G +Q+EA + QY PL+ + CS LK FL
Sbjct: 41 PVLMPNMFGHRSQDEANHVIQQYKPLISVACSPFLKPFL 79
>UniRef50_Q9W3H0 Cluster: CG1632-PA; n=5; Diptera|Rep: CG1632-PA -
Drosophila melanogaster (Fruit fly)
Length = 1056
Score = 34.3 bits (75), Expect = 2.5
Identities = 11/24 (45%), Positives = 17/24 (70%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNAL 504
RC + + CR +GYN+T++PN L
Sbjct: 384 RCSPLELSYCRQVGYNITTYPNLL 407
>UniRef50_Q4H2U5 Cluster: Secreted frizzled-related protein; n=1;
Ciona intestinalis|Rep: Secreted frizzled-related
protein - Ciona intestinalis (Transparent sea squirt)
Length = 365
Score = 34.3 bits (75), Expect = 2.5
Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Frame = +1
Query: 436 CQDI--TIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVY 609
C DI ++ +CR +GY PN L+ + + T+ P LCS++
Sbjct: 52 CVDIPTSLKLCRNVGYTRMVLPNLLNHESLTEVVQQATSFVPLLSRHCHANVQVFLCSLF 111
Query: 610 TPICI 624
P+CI
Sbjct: 112 APVCI 116
>UniRef50_A0CYS2 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 2220
Score = 34.3 bits (75), Expect = 2.5
Identities = 17/47 (36%), Positives = 29/47 (61%)
Frame = -1
Query: 168 MRYFRYGRHVSITCDIRYFVYYYFNEALLKVIYLSLISCARFKTITS 28
+ YF +G H+ I + +YFVY + + LL +I +S +C + +ITS
Sbjct: 73 LTYFLFGYHI-IYVEKQYFVYALYKQFLLIIIKISNKNCDQLLSITS 118
>UniRef50_UPI0000E48FF8 Cluster: PREDICTED: similar to fibropellin
Ib, partial; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to fibropellin Ib, partial -
Strongylocentrotus purpuratus
Length = 1037
Score = 33.9 bits (74), Expect = 3.3
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Frame = +1
Query: 430 PRCQDITIPMCR-GIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSV 606
P C+ + +CR + YNLT FPN T FT++G +CSV
Sbjct: 157 PYCEQVQFDICRQSLAYNLTFFPNRNAETADAAAG-NFTDMG-TTISSCHDHLFPFMCSV 214
Query: 607 YTPIC 621
Y P C
Sbjct: 215 YYPEC 219
>UniRef50_UPI00015B523C Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 779
Score = 33.1 bits (72), Expect = 5.7
Identities = 16/66 (24%), Positives = 25/66 (37%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVYT 612
RC I C+ + YN+TS+PN ++ + +C V
Sbjct: 235 RCSPIEFSYCKHLPYNVTSYPNFFGHNDAREVNDDIIAFRELVDAECYKQAYDFICQVLQ 294
Query: 613 PICIEG 630
P C+EG
Sbjct: 295 PACLEG 300
>UniRef50_Q552K5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 699
Score = 33.1 bits (72), Expect = 5.7
Identities = 11/17 (64%), Positives = 12/17 (70%)
Frame = +3
Query: 447 HHPHVPRHRLQPHFLPQ 497
HHPH+P H PH LPQ
Sbjct: 481 HHPHIPHHPHHPHQLPQ 497
>UniRef50_Q23FE7 Cluster: Putative uncharacterized protein; n=2;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1404
Score = 33.1 bits (72), Expect = 5.7
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = -2
Query: 356 TFTASSYTATRDTATAPYTLKITQIPLSSQNAPNESMLSFKISIS 222
TF AS++T+ D+ T K+T I N +S+LSFK +I+
Sbjct: 887 TFIASNFTSCADSINQEITSKLTNITDIFSNIAQQSILSFKDTIT 931
>UniRef50_Q16VN8 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 990
Score = 33.1 bits (72), Expect = 5.7
Identities = 9/22 (40%), Positives = 17/22 (77%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTSFPN 498
+C+ + + CR +GYN+T++PN
Sbjct: 335 KCEPLRLNYCRSVGYNMTTYPN 356
>UniRef50_A2DV64 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 429
Score = 33.1 bits (72), Expect = 5.7
Identities = 17/45 (37%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Frame = -3
Query: 292 SHKFHYLLRMHLMNPCYHLKYRSVTRGTTALGRRRIF-LHLTDEI 161
SH+ Y+ +++++N C+H Y +T G L R+RIF LH ++I
Sbjct: 201 SHQQIYVRQLYVVNQCFHAHY--LTAGAYPLLRKRIFDLHHLEQI 243
>UniRef50_Q0IHH5 Cluster: Putative uncharacterized protein; n=1;
Xenopus laevis|Rep: Putative uncharacterized protein -
Xenopus laevis (African clawed frog)
Length = 288
Score = 32.7 bits (71), Expect = 7.5
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 436 CQDI--TIPMCRGIGYNLTSFPNALDPTRRKKPD*RFTNIGPXXXXXXXXXXXXXLCSVY 609
C+ I T+ +C G+GY PN L K+ + + P LCS++
Sbjct: 34 CKSIPGTMTLCHGVGYTEMRLPNLLGHDTMKEALQQAGSWVPLLSKQCHADTKKFLCSLF 93
Query: 610 TPICIEGL 633
P+C+ L
Sbjct: 94 APVCLSEL 101
>UniRef50_A6MT14 Cluster: Frizzled 4; n=7; mojavensis species
complex|Rep: Frizzled 4 - Drosophila mojavensis (Fruit
fly)
Length = 64
Score = 32.7 bits (71), Expect = 7.5
Identities = 13/19 (68%), Positives = 15/19 (78%)
Frame = +1
Query: 433 RCQDITIPMCRGIGYNLTS 489
+C+ I I MCRGIGYN TS
Sbjct: 45 QCEPIRIEMCRGIGYNETS 63
>UniRef50_Q9BY79 Cluster: Membrane frizzled-related protein; n=15;
Theria|Rep: Membrane frizzled-related protein - Homo
sapiens (Human)
Length = 579
Score = 32.7 bits (71), Expect = 7.5
Identities = 10/21 (47%), Positives = 15/21 (71%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPN 498
C+ + + MC G+ YN T+FPN
Sbjct: 466 CEPVQVEMCLGLSYNTTAFPN 486
>UniRef50_Q61089 Cluster: Frizzled-6 precursor; n=21;
Euteleostomi|Rep: Frizzled-6 precursor - Mus musculus
(Mouse)
Length = 709
Score = 32.7 bits (71), Expect = 7.5
Identities = 11/23 (47%), Positives = 16/23 (69%)
Frame = +1
Query: 436 CQDITIPMCRGIGYNLTSFPNAL 504
C+ IT+P C + YN+T FPN +
Sbjct: 24 CEPITVPRCMKMTYNMTFFPNLM 46
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 590,082,381
Number of Sequences: 1657284
Number of extensions: 10839325
Number of successful extensions: 27437
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 25768
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27329
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46881492319
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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