Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-2089
(450 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SBK1 Cluster: Chromosome 15 SCAF14667, whole genome s... 79 4e-14
UniRef50_Q96BD6 Cluster: SPRY domain-containing SOCS box protein... 79 4e-14
UniRef50_Q96A44 Cluster: SPRY domain-containing SOCS box protein... 78 1e-13
UniRef50_Q8WST3 Cluster: Ci-META3; n=1; Ciona intestinalis|Rep: ... 72 5e-12
UniRef50_Q965N6 Cluster: Putative uncharacterized protein; n=4; ... 69 4e-11
UniRef50_O88838-2 Cluster: Isoform 2 of O88838 ; n=2; Eutheria|R... 66 3e-10
UniRef50_UPI0000E20195 Cluster: PREDICTED: similar to F-box prot... 58 7e-08
UniRef50_P0C2W1 Cluster: F-box/SPRY domain-containing protein 1;... 58 7e-08
UniRef50_Q9V6L9 Cluster: F-box/SPRY domain-containing protein 1;... 54 1e-06
UniRef50_Q4RI70 Cluster: Chromosome 8 SCAF15044, whole genome sh... 54 1e-06
UniRef50_A7M6E3 Cluster: F-box/SPRY-domain protein 1; n=1; Duges... 50 3e-05
UniRef50_A7RJX3 Cluster: Predicted protein; n=2; Nematostella ve... 37 0.18
UniRef50_Q7PRH2 Cluster: ENSANGP00000025195; n=2; Culicidae|Rep:... 32 6.6
UniRef50_UPI0001555D3E Cluster: PREDICTED: similar to erythrobla... 31 8.8
>UniRef50_Q4SBK1 Cluster: Chromosome 15 SCAF14667, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14667, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 411
Score = 79.0 bits (186), Expect = 4e-14
Identities = 32/45 (71%), Positives = 41/45 (91%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GTHAVVGVATS APLHSVGY +LVG+ +SWGWDLGR++++H++K
Sbjct: 120 GTHAVVGVATSEAPLHSVGYTALVGSDCESWGWDLGRHRLYHDSK 164
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/149 (30%), Positives = 59/149 (39%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVWPXXXXXXXXXXXXXXXXXXXXLSRLSESSRGHRSEL 181
AQSTDCIRGR GYTRGLH W++ WP +
Sbjct: 91 AQSTDCIRGRVGYTRGLHVWKIHWPARQRGTHAVVGVATSEAPLHSVGYTALVGSDCESW 150
Query: 182 GLGFG*K*XXXXXXXXXXXXXXXXXXXXXXXEQFLVPDRVLVVLDMDEGTLAFCADGRYL 361
G G + F +PD +LV+LDMDEGTL+F DG+YL
Sbjct: 151 GWDLGRHRLYHDSKNRAHSSLSSYPSFLEPEDSFTLPDSLLVILDMDEGTLSFMVDGQYL 210
Query: 362 RRRGARPCAERXSTPSXPXVWGTPXITIE 448
R + P VWG I+++
Sbjct: 211 -GVAFRGLKGKKLYPVVSAVWGHCEISMK 238
>UniRef50_Q96BD6 Cluster: SPRY domain-containing SOCS box protein 1;
n=23; Amniota|Rep: SPRY domain-containing SOCS box
protein 1 - Homo sapiens (Human)
Length = 273
Score = 79.0 bits (186), Expect = 4e-14
Identities = 32/45 (71%), Positives = 39/45 (86%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GTHAVVGVAT+ APLHSVGY +LVG +SWGWDLGRN+++H+ K
Sbjct: 110 GTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGK 154
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/24 (70%), Positives = 20/24 (83%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVW 73
AQSTD IRG+ GYTRGLH W++ W
Sbjct: 81 AQSTDAIRGKVGYTRGLHVWQITW 104
Score = 45.2 bits (102), Expect = 7e-04
Identities = 23/51 (45%), Positives = 29/51 (56%)
Frame = +2
Query: 275 EQFLVPDRVLVVLDMDEGTLAFCADGRYLRRRGARPCAERXSTPSXPXVWG 427
E F+VPD LV LDMD+GTL+F DG+Y+ R + P VWG
Sbjct: 169 ETFIVPDSFLVALDMDDGTLSFIVDGQYM-GVAFRGLKGKKLYPVVSAVWG 218
>UniRef50_Q96A44 Cluster: SPRY domain-containing SOCS box protein 4;
n=43; Eumetazoa|Rep: SPRY domain-containing SOCS box
protein 4 - Homo sapiens (Human)
Length = 273
Score = 77.8 bits (183), Expect = 1e-13
Identities = 31/45 (68%), Positives = 40/45 (88%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GTHAVVGVAT+ APLHSVGY +LVG+ +SWGWDLGR++++H+ K
Sbjct: 110 GTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGK 154
Score = 48.4 bits (110), Expect = 7e-05
Identities = 26/57 (45%), Positives = 33/57 (57%)
Frame = +2
Query: 275 EQFLVPDRVLVVLDMDEGTLAFCADGRYLRRRGARPCAERXSTPSXPXVWGTPXITI 445
E F +PD +LVVLDMDEGTL+F DG+YL R + P VWG +T+
Sbjct: 169 EAFALPDSLLVVLDMDEGTLSFIVDGQYL-GVAFRGLKGKKLYPVVSAVWGHCEVTM 224
Score = 44.4 bits (100), Expect = 0.001
Identities = 16/25 (64%), Positives = 20/25 (80%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVWP 76
AQSTD IRG+ G+ RGLH W++ WP
Sbjct: 81 AQSTDGIRGKVGHARGLHAWQINWP 105
>UniRef50_Q8WST3 Cluster: Ci-META3; n=1; Ciona intestinalis|Rep:
Ci-META3 - Ciona intestinalis (Transparent sea squirt)
Length = 319
Score = 72.1 bits (169), Expect = 5e-12
Identities = 29/45 (64%), Positives = 36/45 (80%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GTHA+VGV TS A L +GY+SL+G ++SWGWDLGRNK+FH K
Sbjct: 154 GTHAMVGVCTSEAALTCMGYRSLIGQNNESWGWDLGRNKLFHGGK 198
Score = 50.0 bits (114), Expect = 2e-05
Identities = 18/24 (75%), Positives = 21/24 (87%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVW 73
AQSTD +RG+ GY+RGLHCWEV W
Sbjct: 125 AQSTDGVRGKVGYSRGLHCWEVTW 148
Score = 48.4 bits (110), Expect = 7e-05
Identities = 21/29 (72%), Positives = 26/29 (89%)
Frame = +2
Query: 275 EQFLVPDRVLVVLDMDEGTLAFCADGRYL 361
E F+VP++VLVVLDMDEGTL+F AD +YL
Sbjct: 215 ENFVVPEKVLVVLDMDEGTLSFVADKQYL 243
>UniRef50_Q965N6 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 466
Score = 69.3 bits (162), Expect = 4e-11
Identities = 27/45 (60%), Positives = 37/45 (82%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GTHAVVGVAT +APLH+ GY +L+G TD+S+GWD+ R + H++K
Sbjct: 170 GTHAVVGVATKNAPLHAAGYTALIGTTDESYGWDITRRECHHDSK 214
Score = 49.6 bits (113), Expect = 3e-05
Identities = 17/25 (68%), Positives = 21/25 (84%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVWP 76
AQSTDCIRG+ GY+RG H W++ WP
Sbjct: 141 AQSTDCIRGKMGYSRGFHVWQIEWP 165
Score = 33.9 bits (74), Expect = 1.6
Identities = 18/47 (38%), Positives = 23/47 (48%)
Frame = +2
Query: 287 VPDRVLVVLDMDEGTLAFCADGRYLRRRGARPCAERXSTPSXPXVWG 427
VPD+ +LDMDEG +AF D +L R + P VWG
Sbjct: 232 VPDKFYCILDMDEGYMAFATDDEFL-GVAFRNLKGKTLYPIVAAVWG 277
>UniRef50_O88838-2 Cluster: Isoform 2 of O88838 ; n=2; Eutheria|Rep:
Isoform 2 of O88838 - Mus musculus (Mouse)
Length = 258
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 57/148 (38%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVWPXXXXXXXXXXXXXXXXXXXXLSRLSESSRGHRSEL 181
AQSTD +RG+ GY+RGLH WE+ WP + +
Sbjct: 72 AQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESW 131
Query: 182 GLGFG*K*XXXXXXXXXXXXXXXXXXXXXXXEQFLVPDRVLVVLDMDEGTLAFCADGRYL 361
G G EQ +VP+R+LVVLDM+EGTL + G YL
Sbjct: 132 GWDIG----RGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYL 187
Query: 362 RRRGARPCAERXSTPSXPXVWGTPXITI 445
R R PS VWG + I
Sbjct: 188 -GPAFRGLKGRTLYPSVSAVWGQCQVRI 214
Score = 66.5 bits (155), Expect = 3e-10
Identities = 26/48 (54%), Positives = 37/48 (77%)
Frame = +3
Query: 81 DSAGTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
+ GTHAVVGVAT+ APL + Y +L+G+ +SWGWD+GR K++H +K
Sbjct: 98 EQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSK 145
>UniRef50_UPI0000E20195 Cluster: PREDICTED: similar to F-box protein
45; n=1; Pan troglodytes|Rep: PREDICTED: similar to
F-box protein 45 - Pan troglodytes
Length = 426
Score = 58.4 bits (135), Expect = 7e-08
Identities = 23/45 (51%), Positives = 32/45 (71%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GT AV+G+AT AP+ GY +L+G+ DQSWGW+L N + HN +
Sbjct: 306 GTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGE 350
Score = 33.9 bits (74), Expect = 1.6
Identities = 13/24 (54%), Positives = 16/24 (66%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVW 73
AQSTD R + G++ G H WEV W
Sbjct: 278 AQSTDGARTKIGFSEGRHAWEVWW 301
>UniRef50_P0C2W1 Cluster: F-box/SPRY domain-containing protein 1;
n=26; Coelomata|Rep: F-box/SPRY domain-containing
protein 1 - Homo sapiens (Human)
Length = 286
Score = 58.4 bits (135), Expect = 7e-08
Identities = 23/45 (51%), Positives = 32/45 (71%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
GT AV+G+AT AP+ GY +L+G+ DQSWGW+L N + HN +
Sbjct: 166 GTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGE 210
Score = 33.9 bits (74), Expect = 1.6
Identities = 13/24 (54%), Positives = 16/24 (66%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVW 73
AQSTD R + G++ G H WEV W
Sbjct: 138 AQSTDGARTKIGFSEGRHAWEVWW 161
>UniRef50_Q9V6L9 Cluster: F-box/SPRY domain-containing protein 1;
n=7; Bilateria|Rep: F-box/SPRY domain-containing protein
1 - Drosophila melanogaster (Fruit fly)
Length = 255
Score = 54.4 bits (125), Expect = 1e-06
Identities = 22/43 (51%), Positives = 30/43 (69%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHN 218
GT AV+G++T A L GY +L+G+ DQSWGW+L N + HN
Sbjct: 135 GTVAVIGISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHN 177
Score = 39.5 bits (88), Expect = 0.033
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVW 73
AQSTD RG+ G+ G H WEV+W
Sbjct: 107 AQSTDAARGKIGFRHGRHTWEVIW 130
>UniRef50_Q4RI70 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 205
Score = 54.0 bits (124), Expect = 1e-06
Identities = 19/45 (42%), Positives = 31/45 (68%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
G+HAV+G++ + PL + GY L+G +SWGW+L N+++H K
Sbjct: 27 GSHAVLGISRQNCPLQASGYDVLIGGDSESWGWELRTNQLWHAGK 71
Score = 36.7 bits (81), Expect = 0.23
Identities = 14/25 (56%), Positives = 19/25 (76%)
Frame = +2
Query: 287 VPDRVLVVLDMDEGTLAFCADGRYL 361
+P+R+L+VLD D GTL F DG +L
Sbjct: 106 IPERILLVLDADAGTLGFSVDGSFL 130
Score = 32.3 bits (70), Expect = 5.0
Identities = 11/21 (52%), Positives = 14/21 (66%)
Frame = +2
Query: 11 TDCIRGRTGYTRGLHCWEVVW 73
+D +R TG GLH WEV+W
Sbjct: 1 SDGVRAETGVNSGLHVWEVMW 21
>UniRef50_A7M6E3 Cluster: F-box/SPRY-domain protein 1; n=1; Dugesia
ryukyuensis|Rep: F-box/SPRY-domain protein 1 - Dugesia
ryukyuensis
Length = 352
Score = 49.6 bits (113), Expect = 3e-05
Identities = 21/35 (60%), Positives = 24/35 (68%)
Frame = +3
Query: 90 GTHAVVGVATSHAPLHSVGYQSLVGATDQSWGWDL 194
GTHAVVGV+T L Y SLVG D+SWGWD+
Sbjct: 149 GTHAVVGVSTEKCQLQQDRYVSLVGIDDESWGWDI 183
Score = 41.5 bits (93), Expect = 0.008
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +2
Query: 2 AQSTDCIRGRTGYTRGLHCWEVVWP 76
A STD IRG GY+ G+H WE+ WP
Sbjct: 120 ANSTDGIRGNRGYSEGIHIWEINWP 144
>UniRef50_A7RJX3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 268
Score = 37.1 bits (82), Expect = 0.18
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +3
Query: 81 DSAGTHAVVGVATSHAPLHSVGYQ--SLVGATDQSWGWDLGRNKVFHNAK 224
D GT ++GVAT A LH+ Y+ +LVG +SWG R +++H +
Sbjct: 100 DVRGTSMMIGVATQDAMLHTDNYEYVNLVGRDQESWGLS-HRGEIWHGGQ 148
>UniRef50_Q7PRH2 Cluster: ENSANGP00000025195; n=2; Culicidae|Rep:
ENSANGP00000025195 - Anopheles gambiae str. PEST
Length = 296
Score = 31.9 bits (69), Expect = 6.6
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
Frame = +3
Query: 87 AGTHAVVGVATSHAPL--HSVGYQSLVGATDQSWGWDLGRNKVFHNAK 224
+GT + G+ T L H + S++G DQSWG+ R HN +
Sbjct: 111 SGTDIMFGIGTDKVDLLRHQFSFTSVLGIDDQSWGYSY-RGLAQHNGQ 157
>UniRef50_UPI0001555D3E Cluster: PREDICTED: similar to erythroblast
membrane-associated protein (Scianna blood group),
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to erythroblast membrane-associated protein
(Scianna blood group), partial - Ornithorhynchus
anatinus
Length = 422
Score = 31.5 bits (68), Expect = 8.8
Identities = 10/19 (52%), Positives = 13/19 (68%)
Frame = +2
Query: 11 TDCIRGRTGYTRGLHCWEV 67
T C+ G G+T G HCW+V
Sbjct: 282 TPCVLGSEGFTSGRHCWKV 300
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 319,517,761
Number of Sequences: 1657284
Number of extensions: 4606263
Number of successful extensions: 14999
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 14518
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 14990
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 23604537544
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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