Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-1300
(511 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U55054-1|AAC50563.1| 1085|Homo sapiens K-Cl cotransporter protein. 127 3e-29
BC021193-1|AAH21193.1| 1085|Homo sapiens solute carrier family 1... 127 3e-29
AF054506-1|AAC39685.1| 1068|Homo sapiens erythroid K:Cl cotransp... 127 3e-29
AF054505-1|AAC39684.1| 1011|Homo sapiens erythroid K:Cl cotransp... 127 3e-29
AF047338-1|AAC32815.1| 1085|Homo sapiens erythroid K:Cl cotransp... 127 3e-29
DQ138323-1|ABA02873.1| 1141|Homo sapiens potassium chloride cotr... 126 3e-29
BC126243-1|AAI26244.1| 1099|Homo sapiens solute carrier family 1... 126 3e-29
BC126241-1|AAI26242.1| 1099|Homo sapiens solute carrier family 1... 126 3e-29
BC051744-1|AAH51744.1| 943|Homo sapiens SLC12A6 protein protein. 126 3e-29
AF531260-1|AAQ10028.1| 1091|Homo sapiens K-Cl cotransporter KCC3... 126 3e-29
AF531259-1|AAQ10027.1| 1091|Homo sapiens K-Cl cotransporter KCC3... 126 3e-29
AF531258-1|AAQ10026.1| 1135|Homo sapiens K-Cl cotransporter KCC3... 126 3e-29
AF314956-2|AAM96216.1| 1099|Homo sapiens potassium-chloride tran... 126 3e-29
AF314956-1|AAM96215.1| 1150|Homo sapiens potassium-chloride tran... 126 3e-29
AF116242-1|AAF24986.1| 1150|Homo sapiens K-Cl cotransporter KCC3... 126 3e-29
AF108831-1|AAD25337.1| 1099|Homo sapiens K:Cl cotransporter 3 pr... 126 3e-29
AF105366-1|AAD39742.1| 1150|Homo sapiens K-Cl cotransporter KCC3... 126 3e-29
BC070107-1|AAH70107.2| 1091|Homo sapiens solute carrier family 1... 124 2e-28
AL117500-1|CAB55965.1| 1014|Homo sapiens hypothetical protein pr... 124 2e-28
BC098390-1|AAH98390.1| 1083|Homo sapiens solute carrier family 1... 121 1e-27
BC007760-1|AAH07760.1| 266|Homo sapiens SLC12A7 protein protein. 121 1e-27
AF105365-1|AAD39741.1| 1083|Homo sapiens K-Cl cotransporter KCC4... 121 1e-27
AF477977-1|AAL85335.1| 1011|Homo sapiens K-Cl cotransporter KCC3... 120 4e-27
BC132670-1|AAI32671.1| 1116|Homo sapiens solute carrier family 1... 114 1e-25
BC132668-1|AAI32669.1| 1116|Homo sapiens solute carrier family 1... 114 1e-25
AL162458-7|CAH74054.2| 1116|Homo sapiens solute carrier family 1... 114 1e-25
AL162458-6|CAH74053.1| 285|Homo sapiens solute carrier family 1... 114 1e-25
AF208159-1|AAG43493.1| 1116|Homo sapiens electroneutral potassiu... 114 1e-25
AB033002-1|BAA86490.1| 1101|Homo sapiens KIAA1176 protein protein. 114 1e-25
BC040138-1|AAH40138.1| 430|Homo sapiens SLC12A1 protein protein. 66 7e-11
U58130-1|AAB07364.1| 1099|Homo sapiens bumetanide-sensitive Na-K... 64 4e-10
U30246-1|AAC50561.1| 1212|Homo sapiens bumetanide-sensitive Na-K... 63 5e-10
BC033003-1|AAH33003.1| 1150|Homo sapiens SLC12A2 protein protein. 63 5e-10
AY280459-1|AAP33906.1| 1212|Homo sapiens bumetanide-sensitive Na... 63 5e-10
X91220-1|CAA62613.1| 1021|Homo sapiens NaCl electroneutral Thiaz... 61 3e-09
U44128-1|AAC50355.1| 1030|Homo sapiens thiazide-sensitive Na-Cl ... 61 3e-09
AF312032-7|AAK21009.1| 627|Homo sapiens cation-chloride cotrans... 54 2e-07
AF312032-6|AAK21008.1| 914|Homo sapiens cation-chloride cotrans... 54 2e-07
AF284422-1|AAF88060.1| 914|Homo sapiens cation-chloride cotrans... 54 2e-07
AB033284-1|BAB40456.1| 914|Homo sapiens cation chloride cotrans... 54 2e-07
BC126160-1|AAI26161.1| 714|Homo sapiens solute carrier family 1... 51 2e-06
BC126158-1|AAI26159.1| 714|Homo sapiens solute carrier family 1... 51 2e-06
AF390442-1|AAM73657.1| 731|Homo sapiens solute carrier family 1... 51 2e-06
AF345197-1|AAO49174.1| 714|Homo sapiens cation-chloride cotrans... 51 2e-06
X80507-1|CAA56672.1| 454|Homo sapiens YAP65 (Yes-associated pro... 32 1.0
BC038235-1|AAH38235.1| 504|Homo sapiens YAP1 protein protein. 32 1.0
AY316529-1|AAP92710.1| 488|Homo sapiens yes-associated protein ... 32 1.0
BC018706-1|AAH18706.1| 480|Homo sapiens TNS4 protein protein. 31 2.3
BC016474-1|AAH16474.1| 753|Homo sapiens CCR4-NOT transcription ... 31 2.3
AL133647-1|CAB63766.1| 571|Homo sapiens hypothetical protein pr... 31 2.3
AK160386-1|BAD18729.1| 613|Homo sapiens FLJ00420 protein protein. 31 2.3
AF180474-1|AAF29828.1| 609|Homo sapiens Not3p protein. 31 2.3
AB014591-1|BAA31666.2| 762|Homo sapiens KIAA0691 protein protein. 31 2.3
AY557347-1|AAS67921.1| 174|Homo sapiens unknown protein. 31 3.1
AK027856-1|BAB55413.1| 480|Homo sapiens protein ( Homo sapiens ... 30 4.1
AF417488-1|AAN32666.1| 715|Homo sapiens C-terminal tensin-like ... 30 4.1
AF386649-1|AAL26987.1| 1362|Homo sapiens bromodomain-containing ... 30 4.1
BC013013-1|AAH13013.1| 670|Homo sapiens zinc finger protein 526... 30 5.4
AB075831-1|BAB85537.1| 679|Homo sapiens KIAA1951 protein protein. 30 5.4
U27185-1|AAA99722.1| 228|Homo sapiens TIG1 protein. 29 7.1
BC029640-1|AAH29640.1| 294|Homo sapiens retinoic acid receptor ... 29 7.1
AJ005333-1|CAA06480.1| 31|Homo sapiens Na-K-2Cl cotransporter ... 29 7.1
AB209811-1|BAD93048.1| 501|Homo sapiens epsilon isoform of regu... 29 7.1
AB032527-1|BAA84576.1| 31|Homo sapiens Na-K-2Cl cotransporter ... 29 7.1
BC071599-1|AAH71599.1| 1121|Homo sapiens pleckstrin homology dom... 29 9.4
BC033239-1|AAH33239.1| 748|Homo sapiens PLEKHA7 protein protein. 29 9.4
AF057170-1|AAC64344.1| 435|Homo sapiens bestrophin protein. 29 9.4
AB040958-1|BAA96049.2| 1135|Homo sapiens KIAA1525 protein protein. 29 9.4
>U55054-1|AAC50563.1| 1085|Homo sapiens K-Cl cotransporter protein.
Length = 1085
Score = 127 bits (306), Expect = 3e-29
Identities = 66/138 (47%), Positives = 82/138 (59%), Gaps = 6/138 (4%)
Frame = +1
Query: 115 RKVTPTNMALPTAQAIKAATLTFMLYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXX 294
R+ +P L ++ I L+ EE++ RP+ ++ L L Y N
Sbjct: 44 RESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAE 103
Query: 295 XXXXXXXR------MGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCT 456
R MGTL+GVYLPC+QNIFGVILF+RLTW+VGTAG +Q LIVL CCC
Sbjct: 104 SGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCC 163
Query: 457 TMLTAISMSAIATRGVVP 510
T+LTAISMSAIAT GVVP
Sbjct: 164 TLLTAISMSAIATNGVVP 181
>BC021193-1|AAH21193.1| 1085|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 4 protein.
Length = 1085
Score = 127 bits (306), Expect = 3e-29
Identities = 66/138 (47%), Positives = 82/138 (59%), Gaps = 6/138 (4%)
Frame = +1
Query: 115 RKVTPTNMALPTAQAIKAATLTFMLYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXX 294
R+ +P L ++ I L+ EE++ RP+ ++ L L Y N
Sbjct: 44 RESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAE 103
Query: 295 XXXXXXXR------MGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCT 456
R MGTL+GVYLPC+QNIFGVILF+RLTW+VGTAG +Q LIVL CCC
Sbjct: 104 SGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCC 163
Query: 457 TMLTAISMSAIATRGVVP 510
T+LTAISMSAIAT GVVP
Sbjct: 164 TLLTAISMSAIATNGVVP 181
>AF054506-1|AAC39685.1| 1068|Homo sapiens erythroid K:Cl
cotransporter splicing isoform 2 protein.
Length = 1068
Score = 127 bits (306), Expect = 3e-29
Identities = 66/138 (47%), Positives = 82/138 (59%), Gaps = 6/138 (4%)
Frame = +1
Query: 115 RKVTPTNMALPTAQAIKAATLTFMLYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXX 294
R+ +P L ++ I L+ EE++ RP+ ++ L L Y N
Sbjct: 44 RESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAE 103
Query: 295 XXXXXXXR------MGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCT 456
R MGTL+GVYLPC+QNIFGVILF+RLTW+VGTAG +Q LIVL CCC
Sbjct: 104 SGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCC 163
Query: 457 TMLTAISMSAIATRGVVP 510
T+LTAISMSAIAT GVVP
Sbjct: 164 TLLTAISMSAIATNGVVP 181
>AF054505-1|AAC39684.1| 1011|Homo sapiens erythroid K:Cl
cotransporter splicing isoform 1 protein.
Length = 1011
Score = 127 bits (306), Expect = 3e-29
Identities = 66/138 (47%), Positives = 82/138 (59%), Gaps = 6/138 (4%)
Frame = +1
Query: 115 RKVTPTNMALPTAQAIKAATLTFMLYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXX 294
R+ +P L ++ I L+ EE++ RP+ ++ L L Y N
Sbjct: 44 RESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAE 103
Query: 295 XXXXXXXR------MGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCT 456
R MGTL+GVYLPC+QNIFGVILF+RLTW+VGTAG +Q LIVL CCC
Sbjct: 104 SGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCC 163
Query: 457 TMLTAISMSAIATRGVVP 510
T+LTAISMSAIAT GVVP
Sbjct: 164 TLLTAISMSAIATNGVVP 181
>AF047338-1|AAC32815.1| 1085|Homo sapiens erythroid K:Cl
cotransporter protein.
Length = 1085
Score = 127 bits (306), Expect = 3e-29
Identities = 66/138 (47%), Positives = 82/138 (59%), Gaps = 6/138 (4%)
Frame = +1
Query: 115 RKVTPTNMALPTAQAIKAATLTFMLYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXX 294
R+ +P L ++ I L+ EE++ RP+ ++ L L Y N
Sbjct: 44 RESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAE 103
Query: 295 XXXXXXXR------MGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCT 456
R MGTL+GVYLPC+QNIFGVILF+RLTW+VGTAG +Q LIVL CCC
Sbjct: 104 SGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCC 163
Query: 457 TMLTAISMSAIATRGVVP 510
T+LTAISMSAIAT GVVP
Sbjct: 164 TLLTAISMSAIATNGVVP 181
>DQ138323-1|ABA02873.1| 1141|Homo sapiens potassium chloride
cotransporter KCC3a-S3 protein.
Length = 1141
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 126 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 185
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 186 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 239
>BC126243-1|AAI26244.1| 1099|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 6 protein.
Length = 1099
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 84 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 143
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 144 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
>BC126241-1|AAI26242.1| 1099|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 6 protein.
Length = 1099
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 84 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 143
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 144 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
>BC051744-1|AAH51744.1| 943|Homo sapiens SLC12A6 protein protein.
Length = 943
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 76 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 135
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 136 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
>AF531260-1|AAQ10028.1| 1091|Homo sapiens K-Cl cotransporter
KCC3a-S2 isoform protein.
Length = 1091
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 76 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 135
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 136 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
>AF531259-1|AAQ10027.1| 1091|Homo sapiens K-Cl cotransporter
KCC3a-S1 isoform protein.
Length = 1091
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 76 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 135
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 136 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
>AF531258-1|AAQ10026.1| 1135|Homo sapiens K-Cl cotransporter
KCC3a-X2M isoform protein.
Length = 1135
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 120 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 179
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 180 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 233
>AF314956-2|AAM96216.1| 1099|Homo sapiens potassium-chloride
transporter-3b protein.
Length = 1099
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 84 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 143
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 144 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
>AF314956-1|AAM96215.1| 1150|Homo sapiens potassium-chloride
transporter-3a protein.
Length = 1150
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 135 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 194
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 195 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 248
>AF116242-1|AAF24986.1| 1150|Homo sapiens K-Cl cotransporter KCC3
protein.
Length = 1150
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 135 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 194
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 195 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 248
>AF108831-1|AAD25337.1| 1099|Homo sapiens K:Cl cotransporter 3
protein.
Length = 1099
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 84 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 143
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 144 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
>AF105366-1|AAD39742.1| 1150|Homo sapiens K-Cl cotransporter KCC3a
protein.
Length = 1150
Score = 126 bits (305), Expect = 3e-29
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVYLP
Sbjct: 135 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLP 194
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 195 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 248
>BC070107-1|AAH70107.2| 1091|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 6 protein.
Length = 1091
Score = 124 bits (298), Expect = 2e-28
Identities = 61/114 (53%), Positives = 75/114 (65%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLP 348
L+ EE++ RP+ ++ L+ +A+Y N + MGT +GVY P
Sbjct: 76 LFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYPP 135
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 136 CLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
>AL117500-1|CAB55965.1| 1014|Homo sapiens hypothetical protein
protein.
Length = 1014
Score = 124 bits (298), Expect = 2e-28
Identities = 61/111 (54%), Positives = 74/111 (66%), Gaps = 6/111 (5%)
Frame = +1
Query: 196 EEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLPCIQ 357
EE++ RP+ ++ L+ +A+Y N + MGT +GVYLPC+Q
Sbjct: 2 EEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQ 61
Query: 358 NIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
NIFGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 62 NIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 112
>BC098390-1|AAH98390.1| 1083|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 7 protein.
Length = 1083
Score = 121 bits (292), Expect = 1e-27
Identities = 59/111 (53%), Positives = 72/111 (64%), Gaps = 3/111 (2%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANT---IXXXXXXXXXXXXXXXXXRMGTLIGVYLPCIQ 357
L+ EE++ P ++ L+ LA+Y N + RMGT IGVYLPC+Q
Sbjct: 71 LFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEESRRREAKAPRMGTFIGVYLPCLQ 130
Query: 358 NIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
NI GVILF+RLTW+VG AG ++ FLIV CC TMLTAISMSAIAT GVVP
Sbjct: 131 NILGVILFLRLTWIVGVAGVLESFLIVAMCCTCTMLTAISMSAIATNGVVP 181
>BC007760-1|AAH07760.1| 266|Homo sapiens SLC12A7 protein protein.
Length = 266
Score = 121 bits (292), Expect = 1e-27
Identities = 59/111 (53%), Positives = 72/111 (64%), Gaps = 3/111 (2%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANT---IXXXXXXXXXXXXXXXXXRMGTLIGVYLPCIQ 357
L+ EE++ P ++ L+ LA+Y N + RMGT IGVYLPC+Q
Sbjct: 71 LFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEESRRREAKAPRMGTFIGVYLPCLQ 130
Query: 358 NIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
NI GVILF+RLTW+VG AG ++ FLIV CC TMLTAISMSAIAT GVVP
Sbjct: 131 NILGVILFLRLTWIVGVAGVLESFLIVAMCCTCTMLTAISMSAIATNGVVP 181
>AF105365-1|AAD39741.1| 1083|Homo sapiens K-Cl cotransporter KCC4
protein.
Length = 1083
Score = 121 bits (292), Expect = 1e-27
Identities = 59/111 (53%), Positives = 72/111 (64%), Gaps = 3/111 (2%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANT---IXXXXXXXXXXXXXXXXXRMGTLIGVYLPCIQ 357
L+ EE++ P ++ L+ LA+Y N + RMGT IGVYLPC+Q
Sbjct: 71 LFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEESRRREAKAPRMGTFIGVYLPCLQ 130
Query: 358 NIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
NI GVILF+RLTW+VG AG ++ FLIV CC TMLTAISMSAIAT GVVP
Sbjct: 131 NILGVILFLRLTWIVGVAGVLESFLIVAMCCTCTMLTAISMSAIATNGVVP 181
>AF477977-1|AAL85335.1| 1011|Homo sapiens K-Cl cotransporter KCC3
variant isoform protein.
Length = 1011
Score = 120 bits (288), Expect = 4e-27
Identities = 59/109 (54%), Positives = 72/109 (66%), Gaps = 6/109 (5%)
Frame = +1
Query: 202 IEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXXR------MGTLIGVYLPCIQNI 363
++ RP+ ++ L+ +A+Y N + MGT +GVYLPC+QNI
Sbjct: 1 MDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNI 60
Query: 364 FGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
FGVILF+RLTWVVGTAG +Q F IVL CCC TMLTAISMSAIAT GVVP
Sbjct: 61 FGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 109
>BC132670-1|AAI32671.1| 1116|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 1116
Score = 114 bits (275), Expect = 1e-25
Identities = 59/114 (51%), Positives = 71/114 (62%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXX------RMGTLIGVYLP 348
L+ EE++ P ++ LS LA+Y N RMGT +GVYLP
Sbjct: 47 LFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLP 106
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVG AG ++ F +V CC TMLTAISMSAIAT GVVP
Sbjct: 107 CLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVP 160
>BC132668-1|AAI32669.1| 1116|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 1116
Score = 114 bits (275), Expect = 1e-25
Identities = 59/114 (51%), Positives = 71/114 (62%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXX------RMGTLIGVYLP 348
L+ EE++ P ++ LS LA+Y N RMGT +GVYLP
Sbjct: 47 LFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLP 106
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVG AG ++ F +V CC TMLTAISMSAIAT GVVP
Sbjct: 107 CLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVP 160
>AL162458-7|CAH74054.2| 1116|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 1116
Score = 114 bits (275), Expect = 1e-25
Identities = 59/114 (51%), Positives = 71/114 (62%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXX------RMGTLIGVYLP 348
L+ EE++ P ++ LS LA+Y N RMGT +GVYLP
Sbjct: 47 LFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLP 106
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVG AG ++ F +V CC TMLTAISMSAIAT GVVP
Sbjct: 107 CLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVP 160
>AL162458-6|CAH74053.1| 285|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 285
Score = 114 bits (275), Expect = 1e-25
Identities = 59/114 (51%), Positives = 71/114 (62%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXX------RMGTLIGVYLP 348
L+ EE++ P ++ LS LA+Y N RMGT +GVYLP
Sbjct: 47 LFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLP 106
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVG AG ++ F +V CC TMLTAISMSAIAT GVVP
Sbjct: 107 CLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVP 160
>AF208159-1|AAG43493.1| 1116|Homo sapiens electroneutral
potassium-chloride cotransporter KCC2 protein.
Length = 1116
Score = 114 bits (275), Expect = 1e-25
Identities = 59/114 (51%), Positives = 71/114 (62%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXX------RMGTLIGVYLP 348
L+ EE++ P ++ LS LA+Y N RMGT +GVYLP
Sbjct: 47 LFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLP 106
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVG AG ++ F +V CC TMLTAISMSAIAT GVVP
Sbjct: 107 CLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVP 160
>AB033002-1|BAA86490.1| 1101|Homo sapiens KIAA1176 protein protein.
Length = 1101
Score = 114 bits (275), Expect = 1e-25
Identities = 59/114 (51%), Positives = 71/114 (62%), Gaps = 6/114 (5%)
Frame = +1
Query: 187 LYHEEIEDRPRAATFLSSLADYANTIXXXXXXXXXXXXXXXXX------RMGTLIGVYLP 348
L+ EE++ P ++ LS LA+Y N RMGT +GVYLP
Sbjct: 39 LFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLP 98
Query: 349 CIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRGVVP 510
C+QNIFGVILF+RLTWVVG AG ++ F +V CC TMLTAISMSAIAT GVVP
Sbjct: 99 CLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVP 152
>BC040138-1|AAH40138.1| 430|Homo sapiens SLC12A1 protein protein.
Length = 430
Score = 66.1 bits (154), Expect = 7e-11
Identities = 32/64 (50%), Positives = 43/64 (67%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
+ G + GV + C+ NI+GV+LFIRL+W+VG AG G LI+L T +T +S SAIAT
Sbjct: 176 KFGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVLIILLSTMVTSITGLSTSAIAT 235
Query: 496 RGVV 507
G V
Sbjct: 236 NGFV 239
>U58130-1|AAB07364.1| 1099|Homo sapiens bumetanide-sensitive
Na-K-2Cl cotransporter protein.
Length = 1099
Score = 63.7 bits (148), Expect = 4e-10
Identities = 31/64 (48%), Positives = 43/64 (67%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
+ G + GV + C+ NI+GV+LFIRL+W+VG AG G +I+ T +T +S SAIAT
Sbjct: 176 KFGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVIIIGLSTIVTTITGMSTSAIAT 235
Query: 496 RGVV 507
GVV
Sbjct: 236 NGVV 239
>U30246-1|AAC50561.1| 1212|Homo sapiens bumetanide-sensitive Na-K-Cl
cotransporter protein.
Length = 1212
Score = 63.3 bits (147), Expect = 5e-10
Identities = 29/64 (45%), Positives = 42/64 (65%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
+ G + GV + C+ NI+GV+LFIRL+W+VG AG L+++ T +T +S SAIAT
Sbjct: 284 KFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIAT 343
Query: 496 RGVV 507
G V
Sbjct: 344 NGFV 347
>BC033003-1|AAH33003.1| 1150|Homo sapiens SLC12A2 protein protein.
Length = 1150
Score = 63.3 bits (147), Expect = 5e-10
Identities = 29/64 (45%), Positives = 42/64 (65%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
+ G + GV + C+ NI+GV+LFIRL+W+VG AG L+++ T +T +S SAIAT
Sbjct: 284 KFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIAT 343
Query: 496 RGVV 507
G V
Sbjct: 344 NGFV 347
>AY280459-1|AAP33906.1| 1212|Homo sapiens bumetanide-sensitive
Na-K-Cl cotransporter protein.
Length = 1212
Score = 63.3 bits (147), Expect = 5e-10
Identities = 29/64 (45%), Positives = 42/64 (65%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
+ G + GV + C+ NI+GV+LFIRL+W+VG AG L+++ T +T +S SAIAT
Sbjct: 284 KFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIAT 343
Query: 496 RGVV 507
G V
Sbjct: 344 NGFV 347
>X91220-1|CAA62613.1| 1021|Homo sapiens NaCl electroneutral
Thiazide-sensitive cotransporter protein.
Length = 1021
Score = 60.9 bits (141), Expect = 3e-09
Identities = 27/64 (42%), Positives = 42/64 (65%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
R G + GV + C+ NI+GVIL++RL W+ AG + ++I+L T +T +S+SAI+T
Sbjct: 135 RFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAIST 194
Query: 496 RGVV 507
G V
Sbjct: 195 NGKV 198
>U44128-1|AAC50355.1| 1030|Homo sapiens thiazide-sensitive Na-Cl
protein.
Length = 1030
Score = 60.9 bits (141), Expect = 3e-09
Identities = 27/64 (42%), Positives = 42/64 (65%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
R G + GV + C+ NI+GVIL++RL W+ AG + ++I+L T +T +S+SAI+T
Sbjct: 135 RFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAIST 194
Query: 496 RGVV 507
G V
Sbjct: 195 NGKV 198
>AF312032-7|AAK21009.1| 627|Homo sapiens cation-chloride
cotransporter-interacting protein 1 isoform b protein.
Length = 627
Score = 54.4 bits (125), Expect = 2e-07
Identities = 23/64 (35%), Positives = 41/64 (64%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
++ T +GV +P + ++F +++F+R+ +VVG AG +Q ++L LT +S+ AIAT
Sbjct: 36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIAT 95
Query: 496 RGVV 507
G V
Sbjct: 96 NGAV 99
>AF312032-6|AAK21008.1| 914|Homo sapiens cation-chloride
cotransporter-interacting protein 1 protein.
Length = 914
Score = 54.4 bits (125), Expect = 2e-07
Identities = 23/64 (35%), Positives = 41/64 (64%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
++ T +GV +P + ++F +++F+R+ +VVG AG +Q ++L LT +S+ AIAT
Sbjct: 36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIAT 95
Query: 496 RGVV 507
G V
Sbjct: 96 NGAV 99
>AF284422-1|AAF88060.1| 914|Homo sapiens cation-chloride
cotransporter-interacting protein protein.
Length = 914
Score = 54.4 bits (125), Expect = 2e-07
Identities = 23/64 (35%), Positives = 41/64 (64%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
++ T +GV +P + ++F +++F+R+ +VVG AG +Q ++L LT +S+ AIAT
Sbjct: 36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIAT 95
Query: 496 RGVV 507
G V
Sbjct: 96 NGAV 99
>AB033284-1|BAB40456.1| 914|Homo sapiens cation chloride
cotransporter 6 protein.
Length = 914
Score = 54.4 bits (125), Expect = 2e-07
Identities = 23/64 (35%), Positives = 41/64 (64%)
Frame = +1
Query: 316 RMGTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIAT 495
++ T +GV +P + ++F +++F+R+ +VVG AG +Q ++L LT +S+ AIAT
Sbjct: 36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIAT 95
Query: 496 RGVV 507
G V
Sbjct: 96 NGAV 99
>BC126160-1|AAI26161.1| 714|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 8 protein.
Length = 714
Score = 51.2 bits (117), Expect = 2e-06
Identities = 22/62 (35%), Positives = 34/62 (54%)
Frame = +1
Query: 322 GTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRG 501
GT GV+ C+ NIFGV+LF+R W+VG G + G +V ++T +S + R
Sbjct: 40 GTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERS 99
Query: 502 VV 507
+
Sbjct: 100 SI 101
>BC126158-1|AAI26159.1| 714|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 8 protein.
Length = 714
Score = 51.2 bits (117), Expect = 2e-06
Identities = 22/62 (35%), Positives = 34/62 (54%)
Frame = +1
Query: 322 GTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRG 501
GT GV+ C+ NIFGV+LF+R W+VG G + G +V ++T +S + R
Sbjct: 40 GTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERS 99
Query: 502 VV 507
+
Sbjct: 100 SI 101
>AF390442-1|AAM73657.1| 731|Homo sapiens solute carrier family 12
member 8 protein.
Length = 731
Score = 51.2 bits (117), Expect = 2e-06
Identities = 22/62 (35%), Positives = 34/62 (54%)
Frame = +1
Query: 322 GTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRG 501
GT GV+ C+ NIFGV+LF+R W+VG G + G +V ++T +S + R
Sbjct: 57 GTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERS 116
Query: 502 VV 507
+
Sbjct: 117 SI 118
>AF345197-1|AAO49174.1| 714|Homo sapiens cation-chloride
cotransporter 9 protein.
Length = 714
Score = 51.2 bits (117), Expect = 2e-06
Identities = 22/62 (35%), Positives = 34/62 (54%)
Frame = +1
Query: 322 GTLIGVYLPCIQNIFGVILFIRLTWVVGTAGAIQGFLIVLTCCCTTMLTAISMSAIATRG 501
GT GV+ C+ NIFGV+LF+R W+VG G + G +V ++T +S + R
Sbjct: 40 GTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERS 99
Query: 502 VV 507
+
Sbjct: 100 SI 101
>X80507-1|CAA56672.1| 454|Homo sapiens YAP65 (Yes-associated
protein of 65kDa MW) protein.
Length = 454
Score = 32.3 bits (70), Expect = 1.0
Identities = 15/26 (57%), Positives = 16/26 (61%)
Frame = +2
Query: 260 QSPRHPPQTQMPPSQPHQPAWARSSA 337
Q P PPQ Q PPS P QPA A + A
Sbjct: 18 QPPSQPPQGQGPPSGPGQPAPAATQA 43
>BC038235-1|AAH38235.1| 504|Homo sapiens YAP1 protein protein.
Length = 504
Score = 32.3 bits (70), Expect = 1.0
Identities = 15/26 (57%), Positives = 16/26 (61%)
Frame = +2
Query: 260 QSPRHPPQTQMPPSQPHQPAWARSSA 337
Q P PPQ Q PPS P QPA A + A
Sbjct: 18 QPPSQPPQGQGPPSGPGQPAPAATQA 43
>AY316529-1|AAP92710.1| 488|Homo sapiens yes-associated protein 2
protein.
Length = 488
Score = 32.3 bits (70), Expect = 1.0
Identities = 15/26 (57%), Positives = 16/26 (61%)
Frame = +2
Query: 260 QSPRHPPQTQMPPSQPHQPAWARSSA 337
Q P PPQ Q PPS P QPA A + A
Sbjct: 18 QPPSQPPQGQGPPSGPGQPAPAATQA 43
>BC018706-1|AAH18706.1| 480|Homo sapiens TNS4 protein protein.
Length = 480
Score = 31.1 bits (67), Expect = 2.3
Identities = 13/34 (38%), Positives = 17/34 (50%)
Frame = +2
Query: 245 RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACTC 346
R Q+PR+P T P PH P A+ A +C
Sbjct: 93 RPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSC 126
>BC016474-1|AAH16474.1| 753|Homo sapiens CCR4-NOT transcription
complex, subunit 3 protein.
Length = 753
Score = 31.1 bits (67), Expect = 2.3
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +2
Query: 197 KRSR-TDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACT 343
KR R TD E +S A+ + + S +HP +PP+ P P A S+ T
Sbjct: 287 KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALST 336
>AL133647-1|CAB63766.1| 571|Homo sapiens hypothetical protein
protein.
Length = 571
Score = 31.1 bits (67), Expect = 2.3
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +2
Query: 197 KRSR-TDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACT 343
KR R TD E +S A+ + + S +HP +PP+ P P A S+ T
Sbjct: 106 KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALST 155
>AK160386-1|BAD18729.1| 613|Homo sapiens FLJ00420 protein protein.
Length = 613
Score = 31.1 bits (67), Expect = 2.3
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +2
Query: 197 KRSR-TDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACT 343
KR R TD E +S A+ + + S +HP +PP+ P P A S+ T
Sbjct: 211 KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALST 260
>AF180474-1|AAF29828.1| 609|Homo sapiens Not3p protein.
Length = 609
Score = 31.1 bits (67), Expect = 2.3
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +2
Query: 197 KRSR-TDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACT 343
KR R TD E +S A+ + + S +HP +PP+ P P A S+ T
Sbjct: 287 KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALST 336
>AB014591-1|BAA31666.2| 762|Homo sapiens KIAA0691 protein protein.
Length = 762
Score = 31.1 bits (67), Expect = 2.3
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +2
Query: 197 KRSR-TDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACT 343
KR R TD E +S A+ + + S +HP +PP+ P P A S+ T
Sbjct: 296 KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALST 345
>AY557347-1|AAS67921.1| 174|Homo sapiens unknown protein.
Length = 174
Score = 30.7 bits (66), Expect = 3.1
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = -2
Query: 348 RQVHADERAHAGWWGWLGGIWVCGG 274
+QV RA +G+WGWLG + + GG
Sbjct: 80 QQVALLRRADSGFWGWLGPLALLGG 104
>AK027856-1|BAB55413.1| 480|Homo sapiens protein ( Homo sapiens
cDNA FLJ14950 fis, clone PLACE2000371, weakly similar to
TENSIN. ).
Length = 480
Score = 30.3 bits (65), Expect = 4.1
Identities = 13/34 (38%), Positives = 16/34 (47%)
Frame = +2
Query: 245 RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACTC 346
R Q+PR+P T P PH P A+ A C
Sbjct: 93 RPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASIC 126
>AF417488-1|AAN32666.1| 715|Homo sapiens C-terminal tensin-like
protein protein.
Length = 715
Score = 30.3 bits (65), Expect = 4.1
Identities = 13/34 (38%), Positives = 16/34 (47%)
Frame = +2
Query: 245 RTMRIQSPRHPPQTQMPPSQPHQPAWARSSACTC 346
R Q+PR+P T P PH P A+ A C
Sbjct: 328 RPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASIC 361
>AF386649-1|AAL26987.1| 1362|Homo sapiens bromodomain-containing 4
protein.
Length = 1362
Score = 30.3 bits (65), Expect = 4.1
Identities = 13/31 (41%), Positives = 16/31 (51%)
Frame = +2
Query: 224 PRSSAR*RTMRIQSPRHPPQTQMPPSQPHQP 316
P S + + + P PPQ Q PP Q HQP
Sbjct: 962 PHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP 992
>BC013013-1|AAH13013.1| 670|Homo sapiens zinc finger protein 526
protein.
Length = 670
Score = 29.9 bits (64), Expect = 5.4
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 227 RSSAR*RTMRIQSPRHPPQTQMPPSQPHQ 313
R AR RT+ +Q PR P PP +P Q
Sbjct: 593 RVHARARTLTLQPPRSPSPAPPPPPEPQQ 621
>AB075831-1|BAB85537.1| 679|Homo sapiens KIAA1951 protein protein.
Length = 679
Score = 29.9 bits (64), Expect = 5.4
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 227 RSSAR*RTMRIQSPRHPPQTQMPPSQPHQ 313
R AR RT+ +Q PR P PP +P Q
Sbjct: 602 RVHARARTLTLQPPRSPSPAPPPPPEPQQ 630
>U27185-1|AAA99722.1| 228|Homo sapiens TIG1 protein.
Length = 228
Score = 29.5 bits (63), Expect = 7.1
Identities = 17/38 (44%), Positives = 20/38 (52%)
Frame = -1
Query: 211 GPRSLRDRA*RLVSQPLLLVPWVVPCSSGSPFFPGEAQ 98
GPR R A L++ LLL P P SG P PG+ Q
Sbjct: 14 GPRGPRPTA-PLLALLLLLAPVAAPAGSGGPDDPGQPQ 50
>BC029640-1|AAH29640.1| 294|Homo sapiens retinoic acid receptor
responder (tazarotene induced) 1 protein.
Length = 294
Score = 29.5 bits (63), Expect = 7.1
Identities = 17/38 (44%), Positives = 20/38 (52%)
Frame = -1
Query: 211 GPRSLRDRA*RLVSQPLLLVPWVVPCSSGSPFFPGEAQ 98
GPR R A L++ LLL P P SG P PG+ Q
Sbjct: 14 GPRGPRPTA-PLLALLLLLAPVAAPAGSGDPDDPGQPQ 50
>AJ005333-1|CAA06480.1| 31|Homo sapiens Na-K-2Cl cotransporter
protein.
Length = 31
Score = 29.5 bits (63), Expect = 7.1
Identities = 15/28 (53%), Positives = 17/28 (60%)
Frame = +1
Query: 424 GFLIVLTCCCTTMLTAISMSAIATRGVV 507
G +I+ T LT ISMSAI T GVV
Sbjct: 2 GVIIIGLSVVVTTLTGISMSAICTNGVV 29
>AB209811-1|BAD93048.1| 501|Homo sapiens epsilon isoform of
regulatory subunit B56, protein phosphatase 2A variant
protein.
Length = 501
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/26 (53%), Positives = 15/26 (57%)
Frame = +3
Query: 279 RRPRCPQASPTSPHGHAHRRVPALHP 356
RRPR P A+ TSP RR P L P
Sbjct: 18 RRPRLPAAARTSPCTSRSRRPPPLRP 43
>AB032527-1|BAA84576.1| 31|Homo sapiens Na-K-2Cl cotransporter
isoform IV protein.
Length = 31
Score = 29.5 bits (63), Expect = 7.1
Identities = 15/28 (53%), Positives = 17/28 (60%)
Frame = +1
Query: 424 GFLIVLTCCCTTMLTAISMSAIATRGVV 507
G +I+ T LT ISMSAI T GVV
Sbjct: 2 GVIIIGLSVVVTTLTGISMSAICTNGVV 29
>BC071599-1|AAH71599.1| 1121|Homo sapiens pleckstrin homology domain
containing, family A member 7 protein.
Length = 1121
Score = 29.1 bits (62), Expect = 9.4
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +2
Query: 200 RSRTDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPA 319
RSR+ LE PRS + + P PP+ PP +PH PA
Sbjct: 553 RSRSMLEVPRSISVPPSPSDIPPPGPPRV-FPPRRPHTPA 591
>BC033239-1|AAH33239.1| 748|Homo sapiens PLEKHA7 protein protein.
Length = 748
Score = 29.1 bits (62), Expect = 9.4
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +2
Query: 200 RSRTDLEQPRSSAR*RTMRIQSPRHPPQTQMPPSQPHQPA 319
RSR+ LE PRS + + P PP+ PP +PH PA
Sbjct: 179 RSRSMLEVPRSISVPPSPSDIPPPGPPRV-FPPRRPHTPA 217
>AF057170-1|AAC64344.1| 435|Homo sapiens bestrophin protein.
Length = 435
Score = 29.1 bits (62), Expect = 9.4
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 1/31 (3%)
Frame = +2
Query: 245 RTMRIQSPRHPPQTQM-PPSQPHQPAWARSS 334
RT SP H P TQ+ PPS P WA S
Sbjct: 402 RTCTGISPSHSPPTQLLPPSSVEPPLWAPPS 432
>AB040958-1|BAA96049.2| 1135|Homo sapiens KIAA1525 protein protein.
Length = 1135
Score = 29.1 bits (62), Expect = 9.4
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 11/83 (13%)
Frame = +3
Query: 123 DPDEHGTTHGTSNKGCDTNLYALSRRDR--------GPT*SSHVPQLASGL-CEYNP--H 269
+P E+ + SN C + ALSRR GP SH SGL Y P
Sbjct: 941 NPQEYPDFYDFSNAACRPSTPALSRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQT 1000
Query: 270 GIRRRPRCPQASPTSPHGHAHRR 338
+++ + P SP GH HR+
Sbjct: 1001 SPKKQEEARREYPLSPDGHLHRQ 1023
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,816,897
Number of Sequences: 237096
Number of extensions: 1885844
Number of successful extensions: 8391
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 6857
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8293
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4763295768
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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