Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-1258
(620 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q6GLC2 Cluster: Adenylosuccinate lyase; n=13; cellular ... 267 1e-70
UniRef50_P30566 Cluster: Adenylosuccinate lyase; n=74; cellular ... 255 7e-67
UniRef50_Q97I33 Cluster: Adenylosuccinate lyase; n=32; cellular ... 229 4e-59
UniRef50_A6G4E8 Cluster: Adenylosuccinate lyase; n=2; Bacteria|R... 198 7e-50
UniRef50_Q6QNT8 Cluster: Adenylosuccinate lyase; n=6; Borrelia|R... 168 8e-41
UniRef50_Q21774 Cluster: Adenylosuccinate lyase; n=3; Caenorhabd... 161 2e-38
UniRef50_Q5C1G4 Cluster: SJCHGC07580 protein; n=1; Schistosoma j... 121 1e-26
UniRef50_O05745 Cluster: PurB; n=37; Bacteria|Rep: PurB - Mycoba... 86 7e-16
UniRef50_Q58339 Cluster: Adenylosuccinate lyase; n=8; Euryarchae... 85 1e-15
UniRef50_Q9UZ99 Cluster: Adenylosuccinate lyase; n=11; Euryarcha... 81 3e-14
UniRef50_UPI00015BD1D1 Cluster: UPI00015BD1D1 related cluster; n... 79 6e-14
UniRef50_Q980P8 Cluster: Adenylosuccinate lyase; n=5; Thermoprot... 76 6e-13
UniRef50_Q6L0V1 Cluster: Adenylosuccinate lyase; n=4; Thermoplas... 76 6e-13
UniRef50_Q46EP0 Cluster: Adenylosuccinate lyase; n=6; Methanomic... 75 2e-12
UniRef50_P74384 Cluster: Adenylosuccinate lyase; n=37; Bacteria|... 74 3e-12
UniRef50_Q67KF3 Cluster: Adenylosuccinate lyase; n=6; Bacteria|R... 72 1e-11
UniRef50_Q8F1P9 Cluster: Adenylosuccinate lyase; n=5; Bacteria|R... 71 3e-11
UniRef50_O66856 Cluster: Adenylosuccinate lyase; n=65; cellular ... 71 3e-11
UniRef50_A0RWI2 Cluster: Adenylosuccinate lyase; n=3; Crenarchae... 70 5e-11
UniRef50_Q3EYD1 Cluster: Adenylosuccinate lyase; n=1; Bacillus t... 69 9e-11
UniRef50_Q5LZ30 Cluster: Adenylosuccinate lyase, putative; n=1; ... 69 1e-10
UniRef50_Q11C84 Cluster: Fumarate lyase; n=16; cellular organism... 68 2e-10
UniRef50_Q3AHI4 Cluster: Adenylosuccinate lyase; n=3; Bacteria|R... 66 5e-10
UniRef50_Q9X0I0 Cluster: Adenylosuccinate lyase; n=5; Thermotoga... 66 5e-10
UniRef50_P72478 Cluster: Adenylosuccinate lyase; n=34; Bacteria|... 65 1e-09
UniRef50_Q9RSE6 Cluster: Adenylosuccinate lyase; n=17; Bacteria|... 64 2e-09
UniRef50_Q3AZP0 Cluster: Adenylosuccinate lyase; n=41; Bacteria|... 64 3e-09
UniRef50_A1G7D0 Cluster: Fumarate lyase; n=1; Salinispora arenic... 64 3e-09
UniRef50_Q4J4Y6 Cluster: Adenylosuccinate lyase; n=1; Azotobacte... 62 1e-08
UniRef50_Q6FZJ4 Cluster: Adenylosuccinate lyase; n=25; Bacteria|... 61 2e-08
UniRef50_Q6D3A2 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 61 2e-08
UniRef50_Q5WG84 Cluster: Adenylosuccinate lyase; n=1; Bacillus c... 61 2e-08
UniRef50_Q1VP16 Cluster: Adenylosuccinate lyase; n=1; Psychrofle... 59 7e-08
UniRef50_Q2AIU7 Cluster: Fumarate lyase; n=1; Halothermothrix or... 59 1e-07
UniRef50_Q13PC6 Cluster: Putative lyase; n=1; Burkholderia xenov... 59 1e-07
UniRef50_A1SC86 Cluster: Fumarate lyase; n=2; Nocardioides sp. J... 58 2e-07
UniRef50_A4X707 Cluster: Adenylosuccinate lyase; n=3; Actinomyce... 57 4e-07
UniRef50_Q8ZY28 Cluster: Adenylosuccinate lyase; n=4; Pyrobaculu... 57 4e-07
UniRef50_Q8EVI2 Cluster: Adenylosuccinate lyase; n=1; Mycoplasma... 56 7e-07
UniRef50_A5G255 Cluster: Fumarate lyase; n=1; Acidiphilium crypt... 56 7e-07
UniRef50_Q9C8F5 Cluster: Adenylosuccinate lyase-like protein; 10... 56 7e-07
UniRef50_Q9A5N7 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 55 1e-06
UniRef50_Q5FNL5 Cluster: Adenylosuccinate lyase; n=62; Bacteria|... 54 2e-06
UniRef50_Q7MJB9 Cluster: Adenylosuccinate lyase; n=3; Gammaprote... 54 4e-06
UniRef50_Q6MLQ8 Cluster: PurB protein; n=1; Bdellovibrio bacteri... 53 5e-06
UniRef50_Q0SJY5 Cluster: Probable adenylosuccinate lyase; n=1; R... 53 5e-06
UniRef50_A5G1E3 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 53 6e-06
UniRef50_O49514 Cluster: Adenylosuccinate lyase - like protein; ... 52 8e-06
UniRef50_A3XE63 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 51 2e-05
UniRef50_Q9HS42 Cluster: Adenylosuccinate lyase; n=4; Halobacter... 51 2e-05
UniRef50_A3JVW8 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 50 3e-05
UniRef50_Q3E4V0 Cluster: Adenylosuccinate lyase; n=3; Chloroflex... 50 6e-05
UniRef50_P44797 Cluster: Adenylosuccinate lyase; n=32; Gammaprot... 50 6e-05
UniRef50_A7D364 Cluster: Adenylosuccinate lyase; n=1; Halorubrum... 49 8e-05
UniRef50_Q1AVN7 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 49 1e-04
UniRef50_A1B7S2 Cluster: Fumarate lyase; n=2; Paracoccus denitri... 49 1e-04
UniRef50_Q9XAN2 Cluster: Putative 3-carboxy-cis,cis-muconate cyc... 48 2e-04
UniRef50_Q9HY92 Cluster: Probable lyase; n=7; Pseudomonas aerugi... 47 3e-04
UniRef50_Q2J4S4 Cluster: Adenylosuccinate lyase; n=4; Actinomyce... 47 3e-04
UniRef50_Q1YSL1 Cluster: Adenylosuccinate lyase; n=1; gamma prot... 47 3e-04
UniRef50_Q02CF9 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 47 3e-04
UniRef50_A7IQF6 Cluster: Fumarate lyase; n=3; Xanthobacter autot... 47 3e-04
UniRef50_A3H8P9 Cluster: Adenylosuccinate lyase; n=1; Caldivirga... 47 3e-04
UniRef50_P56468 Cluster: Adenylosuccinate lyase; n=47; Bacteria|... 47 3e-04
UniRef50_Q5LKE9 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 47 4e-04
UniRef50_Q83FF1 Cluster: Adenylosuccinate lyase; n=2; Tropheryma... 46 6e-04
UniRef50_Q73MK9 Cluster: Adenylosuccinate lyase, putative; n=1; ... 46 6e-04
UniRef50_Q9I6Q8 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 46 6e-04
UniRef50_A0HE34 Cluster: Fumarate lyase; n=2; Comamonadaceae|Rep... 46 7e-04
UniRef50_Q8G3G1 Cluster: Adenylosuccinate lyase; n=9; Actinobact... 46 0.001
UniRef50_P0AB90 Cluster: Adenylosuccinate lyase; n=215; cellular... 45 0.001
UniRef50_Q12CF4 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 45 0.002
UniRef50_A6WG20 Cluster: Adenylosuccinate lyase; n=2; Bacteria|R... 44 0.002
UniRef50_A1A0V2 Cluster: Adenylosuccinate lyase; n=3; Actinobact... 44 0.002
UniRef50_A7AM59 Cluster: Adenylosuccinate lyase, putative; n=1; ... 44 0.003
UniRef50_Q8NN17 Cluster: Adenylosuccinate lyase; n=3; Corynebact... 44 0.004
UniRef50_Q6D4E7 Cluster: Adenylosuccinate lyase; n=36; Proteobac... 43 0.005
UniRef50_A4EGL0 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 42 0.009
UniRef50_A3VZD3 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 42 0.012
UniRef50_Q59092 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 42 0.016
UniRef50_Q9U0T7 Cluster: Adenylosuccinate lyase; n=36; cellular ... 40 0.036
UniRef50_P52201 Cluster: Adenylosuccinate lyase; n=5; Mollicutes... 40 0.036
UniRef50_A0P1F3 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 39 0.084
UniRef50_Q11F19 Cluster: Argininosuccinate lyase; n=1; Mesorhizo... 39 0.11
UniRef50_Q23FJ3 Cluster: Adenylosuccinate lyase family protein; ... 39 0.11
UniRef50_A6F014 Cluster: Fumarate lyase; n=1; Marinobacter algic... 38 0.15
UniRef50_Q8U705 Cluster: Argininosuccinate lyase 2; n=3; Alphapr... 37 0.34
UniRef50_Q0SH25 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 37 0.45
UniRef50_UPI00015BD1CB Cluster: UPI00015BD1CB related cluster; n... 36 0.78
UniRef50_Q311J1 Cluster: Amino acid adenylation; n=9; Bacteria|R... 36 1.0
UniRef50_Q92VM6 Cluster: Argininosuccinate lyase 2; n=37; Bacter... 36 1.0
UniRef50_Q58201 Cluster: Argininosuccinate lyase; n=9; Euryarcha... 35 1.4
UniRef50_A0Z9A4 Cluster: SyrP protein, putative; n=3; Proteobact... 35 1.8
UniRef50_A0CTV0 Cluster: Chromosome undetermined scaffold_27, wh... 34 2.4
UniRef50_Q9RV01 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_A6S8F2 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_Q3IVC5 Cluster: Arginino succinate lyase; n=4; Rhodobac... 33 4.2
UniRef50_Q11GN0 Cluster: 3-carboxy-cis,cis-muconate cycloisomera... 33 4.2
UniRef50_Q4MYR8 Cluster: Adenylosuccinate lyase, putative; n=1; ... 33 4.2
UniRef50_Q8ZU95 Cluster: Argininosuccinate lyase; n=4; Pyrobacul... 33 4.2
UniRef50_Q8PUM6 Cluster: Argininosuccinate lyase; n=7; Archaea|R... 33 4.2
UniRef50_Q8TXN9 Cluster: Argininosuccinate lyase; n=1; Methanopy... 33 4.2
UniRef50_Q8UGS2 Cluster: Putative uncharacterized protein Atu096... 33 5.5
UniRef50_Q8DH74 Cluster: Tlr2085 protein; n=1; Synechococcus elo... 33 5.5
UniRef50_Q2LYB8 Cluster: DNA polymerase III subunit gamma/tau; n... 33 5.5
UniRef50_A6DT96 Cluster: Argininosuccinate lyase; n=1; Lentispha... 33 5.5
UniRef50_P39461 Cluster: Fumarate hydratase class II; n=10; Ther... 33 5.5
UniRef50_A3PGB8 Cluster: Histidine kinase precursor; n=3; Rhodob... 33 7.3
UniRef50_A2SE36 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_Q01IZ6 Cluster: OSIGBa0111L12.6 protein; n=1; Oryza sat... 33 7.3
UniRef50_A0D0R1 Cluster: Chromosome undetermined scaffold_33, wh... 33 7.3
UniRef50_Q9WYD8 Cluster: Oligopeptide ABC transporter, permease ... 32 9.6
UniRef50_A2P810 Cluster: RTX protein; n=4; Vibrio cholerae|Rep: ... 32 9.6
UniRef50_Q4UB18 Cluster: Adenylosuccinate lyase, putative; n=1; ... 32 9.6
UniRef50_A7TJF2 Cluster: Putative uncharacterized protein; n=1; ... 32 9.6
>UniRef50_Q6GLC2 Cluster: Adenylosuccinate lyase; n=13; cellular
organisms|Rep: Adenylosuccinate lyase - Xenopus
tropicalis (Western clawed frog) (Silurana tropicalis)
Length = 503
Score = 267 bits (655), Expect = 1e-70
Identities = 124/201 (61%), Positives = 153/201 (76%)
Frame = +3
Query: 18 KMTTIDAPVELQNTEYCNYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELG 197
++T +P+ E YRSPL +RYAS+EM +NFSD KKF TWR+LW++L +A++ LG
Sbjct: 14 RVTGSVSPLTPGPEEVMRYRSPLVSRYASREMAFNFSDSKKFQTWRRLWLWLGQAQRSLG 73
Query: 198 LDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCY 377
L I+ QI E+EA + +IDF AAE EKR+RHDVMAHVHT CP AAP+IHLGATSCY
Sbjct: 74 LPITEEQIQEMEANLENIDFKMAAEEEKRLRHDVMAHVHTFAHCCPKAAPVIHLGATSCY 133
Query: 378 VGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASL 557
VGDNTDLIVL++G +LLLP+L VI +L FA++Y +P LGFTH QPAQLTTVGKRA L
Sbjct: 134 VGDNTDLIVLRDGFDLLLPKLARVISRLADFAERYAEMPTLGFTHYQPAQLTTVGKRACL 193
Query: 558 WLNDLLMDERALSRAKDDLGF 620
WL DL MD R L RA++DL F
Sbjct: 194 WLQDLCMDLRNLERARNDLRF 214
>UniRef50_P30566 Cluster: Adenylosuccinate lyase; n=74; cellular
organisms|Rep: Adenylosuccinate lyase - Homo sapiens
(Human)
Length = 484
Score = 255 bits (624), Expect = 7e-67
Identities = 119/184 (64%), Positives = 145/184 (78%)
Frame = +3
Query: 69 NYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHD 248
+YRSPL++RYAS EM + FSD+ KF TWR+LW++LA+AE+ LGL I+ QI E+++ + +
Sbjct: 12 SYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLEN 71
Query: 249 IDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELL 428
IDF AAE EKR+RHDVMAHVHT G CP AA IIHLGATSCYVGDNTDLI+L+N L+LL
Sbjct: 72 IDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLL 131
Query: 429 LPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
LP+L VI +L FAK+ SLP LGFTH QPAQLTTVGKR LW+ DL MD + L R +D
Sbjct: 132 LPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRD 191
Query: 609 DLGF 620
DL F
Sbjct: 192 DLRF 195
>UniRef50_Q97I33 Cluster: Adenylosuccinate lyase; n=32; cellular
organisms|Rep: Adenylosuccinate lyase - Clostridium
acetobutylicum
Length = 476
Score = 229 bits (560), Expect = 4e-59
Identities = 106/170 (62%), Positives = 130/170 (76%)
Frame = +3
Query: 72 YRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDI 251
Y +PL+TRYASKEM Y FSD KF TWRKLW+ LA++E ELGL+I+ QI EL+A + DI
Sbjct: 5 YETPLNTRYASKEMSYLFSDDMKFRTWRKLWVALAESEMELGLNITNEQINELKAHIDDI 64
Query: 252 DFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLL 431
++ A E EK VRHDVM+HV+ G +CP A IIHLGATSCYVGDN D+I++K L L+
Sbjct: 65 NYDVAQEREKIVRHDVMSHVYAYGVQCPSAKGIIHLGATSCYVGDNADIIIMKEALILIR 124
Query: 432 PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMD 581
+L+ I L FA YKSLP LGFTHLQPAQLTTVGKRA+LW+ DL++D
Sbjct: 125 KKLLNTIHHLSKFALNYKSLPTLGFTHLQPAQLTTVGKRATLWIQDLMID 174
>UniRef50_A6G4E8 Cluster: Adenylosuccinate lyase; n=2; Bacteria|Rep:
Adenylosuccinate lyase - Plesiocystis pacifica SIR-1
Length = 479
Score = 198 bits (484), Expect = 7e-50
Identities = 99/177 (55%), Positives = 122/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 72 YRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDI 251
Y SPLS+RYA+K M NFSD+++ WR LWI LA+AE LGL +S AQI L AA I
Sbjct: 7 YESPLSSRYATKAMLANFSDRRRALLWRDLWIALARAESALGLPVSQAQIEALVAARETI 66
Query: 252 DFPAAAEHEKRVRHDVMAHVHTLGERC-PLAAPIIHLGATSCYVGDNTDLIVLKNGLELL 428
DF AE E +RHDVMAHVH G+ P AA IIHLGATSC+V DN +L++++ GLELL
Sbjct: 67 DFERVAEIEASLRHDVMAHVHHFGDVAGPEAAKIIHLGATSCFVTDNAELVMIREGLELL 126
Query: 429 LPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSR 599
+ RL + QL SFA+ +++ PI +TH QPAQLTTVGKRA LW DL D L +
Sbjct: 127 MDRLYTCLTQLRSFAQTWRAEPIQAYTHFQPAQLTTVGKRACLWAQDLAFDLETLEQ 183
>UniRef50_Q6QNT8 Cluster: Adenylosuccinate lyase; n=6; Borrelia|Rep:
Adenylosuccinate lyase - Borrelia miyamotoi
Length = 467
Score = 168 bits (409), Expect = 8e-41
Identities = 81/176 (46%), Positives = 117/176 (66%), Gaps = 1/176 (0%)
Frame = +3
Query: 72 YRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDI 251
Y +PL +RYASK+M Y FS + K++TWRKLW LA +KELG+DIS Q+ +L + +I
Sbjct: 4 YINPLKSRYASKKMLYIFSPKFKYTTWRKLWYNLALVQKELGIDISKKQLDKLSKHIENI 63
Query: 252 DFPAAAEHEKRVRHDVMAHVHTLGERC-PLAAPIIHLGATSCYVGDNTDLIVLKNGLELL 428
DF ++E++ +H++MAH + + A I+HLG TS Y+ DNTDLI +K L ++
Sbjct: 64 DFEIVKKYEEKFQHEIMAHPYAYADLVGDDARKILHLGVTSAYLTDNTDLIQIKEALLII 123
Query: 429 LPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALS 596
L+ IK L F+ ++K+L L +THLQ AQLTT+GKR+SLWL L+ D L+
Sbjct: 124 KNNLIKFIKSLKEFSTKHKNLTTLAYTHLQKAQLTTLGKRSSLWLQSLIFDFEELN 179
>UniRef50_Q21774 Cluster: Adenylosuccinate lyase; n=3;
Caenorhabditis|Rep: Adenylosuccinate lyase -
Caenorhabditis elegans
Length = 478
Score = 161 bits (390), Expect = 2e-38
Identities = 81/185 (43%), Positives = 116/185 (62%), Gaps = 2/185 (1%)
Frame = +3
Query: 72 YRSPLSTRYASKEMQYNF-SDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVH 245
+ S LSTRY + S+ K + WR+LWI+LA+AEKELGL ++ I E+++
Sbjct: 7 FESVLSTRYCKNSPLVSILSETNKATLWRQLWIWLAEAEKELGLKQVTQDAIDEMKSNRD 66
Query: 246 DIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLEL 425
D+P E++++HDVMAH H G+ CP AA IIHLGATSC+V DN DLI ++ ++
Sbjct: 67 VFDWPFIRSEERKLKHDVMAHNHAFGKLCPTAAGIIHLGATSCFVQDNADLIAYRDSIDH 126
Query: 426 LLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
+L R VI +L +F+ + K + +G TH Q A L TVGKR LW +LLM ++LS +
Sbjct: 127 ILKRFATVIDRLAAFSLKNKEVVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFR 186
Query: 606 DDLGF 620
D + F
Sbjct: 187 DKMRF 191
>UniRef50_Q5C1G4 Cluster: SJCHGC07580 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07580 protein - Schistosoma
japonicum (Blood fluke)
Length = 183
Score = 121 bits (292), Expect = 1e-26
Identities = 62/118 (52%), Positives = 77/118 (65%)
Frame = +3
Query: 180 AEKELGLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHL 359
+ KELG +I+ QI E++ IDF AA EK RHDVMAHV+T CP A+PIIHL
Sbjct: 66 SSKELGFEITDEQIDEMKKQRDSIDFEIAASEEKARRHDVMAHVYTFALACPKASPIIHL 125
Query: 360 GATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLT 533
GATSC+VGDN DLI+ ++ L +LLP+ I +L A +KSL L THLQ AQ T
Sbjct: 126 GATSCFVGDNADLIMFRDALNILLPKGARCIDRLTKTAVLHKSLVCLARTHLQAAQPT 183
>UniRef50_O05745 Cluster: PurB; n=37; Bacteria|Rep: PurB -
Mycobacterium leprae
Length = 487
Score = 85.8 bits (203), Expect = 7e-16
Identities = 52/175 (29%), Positives = 92/175 (52%)
Frame = +3
Query: 84 LSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPA 263
L+ RYAS E+ +S + + R+LW+ + +A+ EL + + IA+ E + ++D +
Sbjct: 22 LAARYASAELVAIWSPEARVIAERQLWLAVLRAQAELSVPMPVKAIADYERVLGEVDLAS 81
Query: 264 AAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLV 443
A E+ +RHDV A + +H G TS + +N + + ++ LEL+ V
Sbjct: 82 IAARERVLRHDVKARIEEFNALA--GHEQVHKGMTSRDLTENVEQLQIRRSLELVFCHGV 139
Query: 444 AVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
AV+ +L A Y+ L + G +H AQ TT+GKR + + L+ AL+R ++
Sbjct: 140 AVVARLAECAVSYRDLVMAGRSHNVAAQATTLGKRFASATQETLI---ALTRLRE 191
>UniRef50_Q58339 Cluster: Adenylosuccinate lyase; n=8;
Euryarchaeota|Rep: Adenylosuccinate lyase -
Methanococcus jannaschii
Length = 462
Score = 85.0 bits (201), Expect = 1e-15
Identities = 57/178 (32%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = +3
Query: 81 PLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDF 257
P+ RY + EM+ + ++ K K+ LAKA+ ELGL AA+ +A+ +
Sbjct: 17 PIDYRYGTPEMRKVWEEENKLEKMLKVEAALAKAQAELGLIPKEAAEEINKKASTKYVKL 76
Query: 258 PAAAEHEKRVRHDVMAHVHTLGERCP-LAAPIIHLGATSCYVGDNTDLIVLKNGLELLLP 434
E EK+ +HDV+A + L E C A IH GATS + D + +++K +E++
Sbjct: 77 ERVKEIEKQTKHDVVAMIRALAEVCEGNAGEYIHFGATSNDIVDTANSLLIKESIEIIED 136
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
+L + L A+++K +G TH Q A TT G R +LW ++ +R L R K+
Sbjct: 137 KLKQLRDILLDKAEEHKYTVCVGRTHGQHAIPTTYGMRFALWAAEI---DRHLERLKE 191
>UniRef50_Q9UZ99 Cluster: Adenylosuccinate lyase; n=11;
Euryarchaeota|Rep: Adenylosuccinate lyase - Pyrococcus
abyssi
Length = 450
Score = 80.6 bits (190), Expect = 3e-14
Identities = 51/177 (28%), Positives = 85/177 (48%), Gaps = 1/177 (0%)
Frame = +3
Query: 81 PLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELG-LDISAAQIAELEAAVHDIDF 257
P+ RY S+EM+ + ++ K + LA+A +LG + +A++ A +
Sbjct: 5 PIDYRYGSEEMRRVWEEENKLQKLLDVEAALARAHAKLGNIPEESARVISERANTKWVKL 64
Query: 258 PAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPR 437
E E + HD+MA V L E C +HLGATS + D + +++K L ++
Sbjct: 65 ERVKEIEAEIHHDIMAVVKALSEVCGEHGKYVHLGATSNDIIDTANALLIKESLAIVEKD 124
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
L + L AK++ +G TH Q A TT G + +LWL+++ L + KD
Sbjct: 125 LKELRSILKELAKKHIDTVCIGRTHGQHAVPTTYGMKFALWLDEIQRHIERLQQLKD 181
>UniRef50_UPI00015BD1D1 Cluster: UPI00015BD1D1 related cluster; n=1;
unknown|Rep: UPI00015BD1D1 UniRef100 entry - unknown
Length = 433
Score = 79.4 bits (187), Expect = 6e-14
Identities = 50/175 (28%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAA 269
RY KEM FS+ K+ W ++ + + A ELG+ A ++ + +A V +
Sbjct: 4 RYTRKEMAEIFSNLNKYKKWLEVELSVLYAMAELGIIPKEAYKVIDSKAYVDESVEKKID 63
Query: 270 EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
E+E+ +HDV+A V +GE+ + H+G TS + D +VLK+ ++ ++ + V
Sbjct: 64 EYERIYKHDVLAFVSAIGEQLGEYSKYFHMGLTSSDILDTALSLVLKDAIDSIIIDIDIV 123
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
++ L A +YK ++G TH A+ +VG + + W ++L + L AK D+
Sbjct: 124 LELLKEKAFRYKDSVMMGRTHGVHAEPISVGLKFASWYDELKRQKERLQVAKKDV 178
>UniRef50_Q980P8 Cluster: Adenylosuccinate lyase; n=5;
Thermoprotei|Rep: Adenylosuccinate lyase - Sulfolobus
solfataricus
Length = 474
Score = 76.2 bits (179), Expect = 6e-13
Identities = 52/176 (29%), Positives = 90/176 (51%)
Frame = +3
Query: 81 PLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFP 260
PL RY S EM+ FS ++ ++ I L KA + GL + + ++E A I
Sbjct: 24 PLEWRYGSNEMRKFFSREEILKRRIQVEIALLKALTKYGL-VKEEDVQKVEKASLTIRPE 82
Query: 261 AAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRL 440
E E ++ HDVMA V + ER + +H GATS + D +V ++ + L+ ++
Sbjct: 83 EVDELESKIGHDVMAMVVLMAERSGDSGRYVHFGATSYDIVDTAYALVFRDAIRLVKTKV 142
Query: 441 VAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
V +++ + S A +YK L ++G TH Q A T+G + + ++ + R+L R +
Sbjct: 143 VEILEMMVSLAIKYKDLAMVGRTHGQHALPITLGFKIANYIYEF---SRSLERLNE 195
>UniRef50_Q6L0V1 Cluster: Adenylosuccinate lyase; n=4;
Thermoplasmatales|Rep: Adenylosuccinate lyase -
Picrophilus torridus
Length = 451
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +3
Query: 78 SPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAV--HDI 251
SP+ RY ++Y FS++ + ++ LA+AE E + IS +++ AV + +
Sbjct: 4 SPIDYRYGRDNVKYIFSEENRMRLMLRVEAALAQAEYEYNI-ISRDAFLDIKNAVDSNSV 62
Query: 252 DFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLL 431
E E R+ HD MA V L E+C +H G TS + D + +K+ ++++
Sbjct: 63 RIERVHEIESRIHHDTMALVEALTEQCSAGKNFVHFGVTSNDIIDTATAMQIKSAVKIIK 122
Query: 432 PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
+ ++K L + K ++G TH Q A T G + S++L+++ + L+ A D
Sbjct: 123 DDIKNLMKTLIKLIDENKDSVMVGRTHGQHASPITFGLKLSVYLDEMSRHLKRLTEAGD 181
>UniRef50_Q46EP0 Cluster: Adenylosuccinate lyase; n=6;
Methanomicrobia|Rep: Adenylosuccinate lyase -
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length = 448
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/165 (27%), Positives = 85/165 (51%), Gaps = 1/165 (0%)
Frame = +3
Query: 81 PLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFP 260
P+ RY + EM++ +S + + + ++ LA+AE ++GL I A + ++ +
Sbjct: 5 PIDYRYGTAEMKHVWSQENRLNKLLQVEAALARAEADMGL-IPADSAEIISESISSVKAE 63
Query: 261 AAAEHEKRVRHDVMAHVHTLGERC-PLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPR 437
E E + HD+MA V + E+C A +H GATS + D + +K+ ++L+ +
Sbjct: 64 RVDEIEAEIHHDMMAVVTAISEQCRDDAGKWVHFGATSNDILDTATALQIKDAIDLMEDK 123
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
L ++ L A+ +K+ G TH Q TT G R ++W +++
Sbjct: 124 LKTLLGVLLDKAEAHKNTVCCGRTHGQIGVPTTYGLRFAIWASEI 168
>UniRef50_P74384 Cluster: Adenylosuccinate lyase; n=37;
Bacteria|Rep: Adenylosuccinate lyase - Synechocystis sp.
(strain PCC 6803)
Length = 431
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/174 (31%), Positives = 86/174 (49%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RY EM ++D K TW + I + +A+ ELG I A + E++A D E
Sbjct: 4 RYTLPEMGKIWTDTYKLQTWLDVEIAVCEAQAELGY-IPQAAVDEIKAKAK-FDPQRVLE 61
Query: 273 HEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
E VRHDV+A + + E A IHLG TS V D + L L+L+L +L +I
Sbjct: 62 IEAEVRHDVIAFLTNVNEYVGDAGRYIHLGLTSSDVLDTALALQLVASLDLILEQLEKLI 121
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
+ + A+Q++ ++G +H A+ T G + + WL ++L + L R +
Sbjct: 122 QAIRYQAQQHRYTVMVGRSHGIHAEPITFGFKLAGWLAEVLRNRDRLVRVAQSI 175
>UniRef50_Q67KF3 Cluster: Adenylosuccinate lyase; n=6; Bacteria|Rep:
Adenylosuccinate lyase - Symbiobacterium thermophilum
Length = 437
Score = 71.7 bits (168), Expect = 1e-11
Identities = 55/175 (31%), Positives = 81/175 (46%), Gaps = 4/175 (2%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDID---FPA 263
RY M +S +F W ++ + +A +LG+ I A +AEL A +D
Sbjct: 4 RYTRPRMAELWSAANRFQKWLEVELLACEAWAKLGV-IPAEAVAELRARAFTVDEAFVRR 62
Query: 264 AAEHEKRVRHDVMAHVHTLGERCPL-AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRL 440
AE E+ RHDV+A + ER AA IH G TS V D VL + + L
Sbjct: 63 VAEIEQTTRHDVIAFTTAVAERIDHPAARYIHYGLTSTDVVDTALSAVLNEAVREIQKGL 122
Query: 441 VAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
+I LG A +YK PI+G TH A+ T+ G + +++ D L +A+
Sbjct: 123 DGLIAALGRQAVRYKDTPIMGRTHGVHAEPTSFGLKLAVFYAQFRRDADRLEQAR 177
>UniRef50_Q8F1P9 Cluster: Adenylosuccinate lyase; n=5; Bacteria|Rep:
Adenylosuccinate lyase - Leptospira interrogans
Length = 433
Score = 70.5 bits (165), Expect = 3e-11
Identities = 42/175 (24%), Positives = 92/175 (52%), Gaps = 1/175 (0%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEA-AVHDIDFPAAA 269
RY++ E+ + + KF W+++ I + + G ++ E+++ A ++D
Sbjct: 4 RYSNPEISKIWELENKFEIWKEIEILACEIRMKRG-EVPQEDFQEIKSKAKFNVD--EIL 60
Query: 270 EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
E E +V HDV+A + + A +H G TS +GD + + ++L+L + ++
Sbjct: 61 EIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDTALCVQMVQAMDLILKKTDSL 120
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
I+ + A QYK+LP +G +H A+ T+G + +L+ +L + + ++ A++++
Sbjct: 121 IEVVREKAIQYKNLPCIGRSHGIHAEPMTLGLKFALFFEELNRNRKRMAEARNEI 175
>UniRef50_O66856 Cluster: Adenylosuccinate lyase; n=65; cellular
organisms|Rep: Adenylosuccinate lyase - Aquifex aeolicus
Length = 437
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/175 (25%), Positives = 87/175 (49%), Gaps = 1/175 (0%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELG-LDISAAQIAELEAAVHDIDFPAAA 269
RY KEM +S+ KF W + I + +A +LG + A + E + V
Sbjct: 4 RYTRKEMGDVWSEVNKFKKWLDVEIAVCRAWAKLGKIPRDALKKIEEKTYVDKKVVEKIK 63
Query: 270 EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
E EK +HDV+A V + E+ IH+G TS V D ++++ ++++L + V
Sbjct: 64 EKEKVFKHDVLAFVSVIAEQVGEEGRYIHMGLTSSDVVDTALALLIREAIDIILKDIDKV 123
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
++++ A ++K ++G TH A+ T G + +W +++ + L A++++
Sbjct: 124 MEEIKRLAFEHKDTLMMGRTHGVHAEPYTFGLKMCVWYDEMRRQKERLLFARENV 178
>UniRef50_A0RWI2 Cluster: Adenylosuccinate lyase; n=3;
Crenarchaeota|Rep: Adenylosuccinate lyase - Cenarchaeum
symbiosum
Length = 451
Score = 69.7 bits (163), Expect = 5e-11
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 3/163 (1%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHD--IDFPAA 266
RY + EM F QKK + A A+ +LG+ I A A++ A +
Sbjct: 10 RYGTPEMLAIFGGQKKVDYQLAVEAAAASAQADLGM-IPRAAAADIRRAARPGGVTESRI 68
Query: 267 AEHEKRVRHDVMAHVHTLGERCPLAA-PIIHLGATSCYVGDNTDLIVLKNGLELLLPRLV 443
E R HD A V LGE+C ++ P IH G TS + D + + +++ L ++ P+
Sbjct: 69 RRLEARSDHDTAALVEALGEKCRVSTRPWIHYGLTSNDLVDTSTSLQMRDALSIVEPKTA 128
Query: 444 AVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
+ L A +Y+ LP +G TH Q A + + G + + W ++
Sbjct: 129 RLAVNLSKMADRYRLLPAVGRTHGQHASIISFGLKFANWAAEM 171
>UniRef50_Q3EYD1 Cluster: Adenylosuccinate lyase; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep:
Adenylosuccinate lyase - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 454
Score = 68.9 bits (161), Expect = 9e-11
Identities = 49/163 (30%), Positives = 80/163 (49%), Gaps = 3/163 (1%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL--DISAAQIAELEAAVHDIDFPAA 266
++ +K+M+ NFSD+ W + LAKAE +LG+ +A IA A + +DF
Sbjct: 17 QFGTKQMRTNFSDENLIQLWLNSEVALAKAEAKLGIIPQNAATNIANA-ADQNKLDFNKI 75
Query: 267 AEHEKRVRHDVMAHVHTLGERCPLAA-PIIHLGATSCYVGDNTDLIVLKNGLELLLPRLV 443
E K+ H +A +H C + IH GAT+ + D + +K EL+ +
Sbjct: 76 REGMKKTGHPFVAFLHEFESLCDEESRKYIHWGATTQDIIDTGLTLQIKGAHELIYNQTQ 135
Query: 444 AVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
++K ++QYKS + G T Q A T G + S+W ++L
Sbjct: 136 EILKICLRLSQQYKSTVMPGRTLGQHALPITFGYKISIWSDEL 178
>UniRef50_Q5LZ30 Cluster: Adenylosuccinate lyase, putative; n=1;
Streptococcus thermophilus CNRZ1066|Rep:
Adenylosuccinate lyase, putative - Streptococcus
thermophilus (strain CNRZ 1066)
Length = 449
Score = 68.5 bits (160), Expect = 1e-10
Identities = 47/174 (27%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Frame = +3
Query: 84 LSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFP 260
L +++ ++ +SD K S + LAK E +LG+ SAA +A V + DF
Sbjct: 10 LQNNFSTPAIRSIWSDDNKISKQLAVEAALAKIEGDLGIIPKSAADKIVEKAKVDNFDFL 69
Query: 261 AAAEHEKRVRHDVMAHVHTLGERC-PLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPR 437
+ + RH ++A +H L E +H G T+ + D ++ K ++L
Sbjct: 70 SLQKESAEKRHSLIALIHALQEEVGGKEGEFVHYGVTTQDIVDTGIMLQTKEAYNIILDH 129
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSR 599
+I L K+++S ++G TH A T G + S+WL++LL +R L +
Sbjct: 130 TKDLISTLAKLTKEHRSTLMIGRTHGIHAIPITFGFKLSIWLDELLRSQRRLKQ 183
>UniRef50_Q11C84 Cluster: Fumarate lyase; n=16; cellular
organisms|Rep: Fumarate lyase - Mesorhizobium sp.
(strain BNC1)
Length = 456
Score = 68.1 bits (159), Expect = 2e-10
Identities = 48/166 (28%), Positives = 83/166 (50%), Gaps = 3/166 (1%)
Frame = +3
Query: 78 SPLSTR-YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDI- 251
SPL R +A +M+ FS Q S + + LA+A+ LG+ I A + AA
Sbjct: 18 SPLYGRSFADDKMRELFSAQSFISRCVETEVALARAQARLGI-IPEDAAAGITAAARTFA 76
Query: 252 -DFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELL 428
+ + + V + ++ V L A +H GAT+ + D ++ +++GL L+
Sbjct: 77 PEMERLRDDTEIVGYPILPLVEQLSAHAGEAGKYLHWGATTQDIMDTATVLQIRDGLALI 136
Query: 429 LPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLN 566
R+ +V K L + A+ ++ P+ G THLQ A T G +A++WL+
Sbjct: 137 SRRIESVRKALAALARNHRDTPMAGRTHLQHALPVTFGYKAAVWLS 182
>UniRef50_Q3AHI4 Cluster: Adenylosuccinate lyase; n=3; Bacteria|Rep:
Adenylosuccinate lyase - Synechococcus sp. (strain
CC9605)
Length = 431
Score = 66.5 bits (155), Expect = 5e-10
Identities = 50/174 (28%), Positives = 79/174 (45%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RY EM +S+Q KF +W + I +A LG A A +++ E
Sbjct: 4 RYTLPEMGAVWSEQAKFQSWLDVEIAATEANCRLGRVPQEALDTIKSKASFEVE--RILE 61
Query: 273 HEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
E VRHDV+A + + E+ A IH+G TS V D + LK + LL L A+
Sbjct: 62 IEAEVRHDVIAFLTNVSEQVGDAGRHIHVGMTSSDVLDTGVALQLKRSVALLRTELDALA 121
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
+ L A+ +K ++G +H + T G + + WL + + L R + D+
Sbjct: 122 EALRDLARAHKGTEMIGRSHAIHGEPITFGFKVAGWLAETERNRIRLDRLEQDV 175
>UniRef50_Q9X0I0 Cluster: Adenylosuccinate lyase; n=5;
Thermotogaceae|Rep: Adenylosuccinate lyase - Thermotoga
maritima
Length = 431
Score = 66.5 bits (155), Expect = 5e-10
Identities = 44/176 (25%), Positives = 83/176 (47%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RY+ M+ ++++ K+ W ++ + + +A +ELG+ + E ID +
Sbjct: 4 RYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKG--VTERIRNNAKIDVELFKK 61
Query: 273 HEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
E++ HDV+A V +G + H G TS V D + + L ++LL L
Sbjct: 62 IEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFC 121
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDLGF 620
L A +YK P +G TH A+ T+ G + W +++ + + L RA +++ +
Sbjct: 122 DVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSY 177
>UniRef50_P72478 Cluster: Adenylosuccinate lyase; n=34;
Bacteria|Rep: Adenylosuccinate lyase - Streptococcus
mutans
Length = 432
Score = 65.3 bits (152), Expect = 1e-09
Identities = 43/160 (26%), Positives = 75/160 (46%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RY+ EM +S++ K+ W ++ I +A ELG +I +A++ D D E
Sbjct: 4 RYSRPEMANIWSEENKYRAWLEVEILADEAWAELG-EIPKEDVAKIREKA-DFDIDRILE 61
Query: 273 HEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
E++ RHDV+A + E +H G TS V D + K ++ L +
Sbjct: 62 IEQQTRHDVVAFTRAVSETLGEERKWVHFGLTSTDVVDTAYGYLYKQANAIIRKDLDNFL 121
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
+ AK++K ++G TH A+ TT G + + W +++
Sbjct: 122 SIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSEM 161
>UniRef50_Q9RSE6 Cluster: Adenylosuccinate lyase; n=17;
Bacteria|Rep: Adenylosuccinate lyase - Deinococcus
radiodurans
Length = 435
Score = 64.5 bits (150), Expect = 2e-09
Identities = 50/175 (28%), Positives = 80/175 (45%), Gaps = 4/175 (2%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEK---ELGLDISAAQIAELEAAVHDIDFPA 263
RY + EM+ +S+ K+ W K+ + +A+ E+ + AA + + EA D F
Sbjct: 4 RYLTPEMKVLWSEANKYRAWLKVELSALQAQARHGEVPAEAHAALVQKSEADPLDDAFAQ 63
Query: 264 -AAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRL 440
AE E RHD++A L ER A IH G TS V D ++L + L++ +
Sbjct: 64 QVAEIEAVTRHDIVAFTRALTERYGEEARFIHHGLTSTDVVDTAQNLLLDEAMGLIITDV 123
Query: 441 VAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
+ + A +K P++G TH A+ T G + W+ L D L A+
Sbjct: 124 QTLREVCRMQAAAHKHTPVVGRTHGIHAEPMTFGLKFLNWMATLDRDLERLQAAR 178
>UniRef50_Q3AZP0 Cluster: Adenylosuccinate lyase; n=41;
Bacteria|Rep: Adenylosuccinate lyase - Synechococcus sp.
(strain CC9902)
Length = 431
Score = 63.7 bits (148), Expect = 3e-09
Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 2/176 (1%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAA- 269
RY EM +S+Q KF +W + I +A LG A LE + F
Sbjct: 4 RYTLPEMGAIWSEQAKFQSWLDVEIAATEANCRLGRVPEEA----LETIKNKASFSVKRI 59
Query: 270 -EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVA 446
E E VRHDV+A + + E A IH+G TS V D + +K + LL L A
Sbjct: 60 LEIEAEVRHDVIAFLTNVNEHVGDAGRHIHVGMTSSDVLDTGLALQMKRSVVLLRIELDA 119
Query: 447 VIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
+ L + A+ +KS ++G +H + T G + + WL + + L R + D+
Sbjct: 120 LADALRTLARAHKSTEMIGRSHAIHGEPITFGFKVAGWLAETERNRSRLERLEADV 175
>UniRef50_A1G7D0 Cluster: Fumarate lyase; n=1; Salinispora arenicola
CNS205|Rep: Fumarate lyase - Salinispora arenicola
CNS205
Length = 471
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/174 (25%), Positives = 82/174 (47%), Gaps = 3/174 (1%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAA--VHDIDFPAA 266
RYA+ + + D + W + LA+A+ ELG+ I A +A + +A + ID A
Sbjct: 30 RYATSGSRRIYCDVCRKQRWLDIEAALAQAQGELGM-IPARAVAGIVSAARLECIDLDAV 88
Query: 267 AEHEKRVRHDVMAHVHTLGERCPL-AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLV 443
R H ++ + L CP IH GAT+ + D + +++ L+ L +
Sbjct: 89 QAEIDRSGHSLVGLLRVLQVACPDDTGEYIHFGATTQDIQDTGQALEMRDTLDELTREIA 148
Query: 444 AVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
A++ L A+Q+ +G TH + A + G + + W+++LL L+ A+
Sbjct: 149 AILASLVELAEQHAGTVAVGRTHARAALPMSFGLKVASWIDELLRHTERLATAR 202
>UniRef50_Q4J4Y6 Cluster: Adenylosuccinate lyase; n=1; Azotobacter
vinelandii AvOP|Rep: Adenylosuccinate lyase -
Azotobacter vinelandii AvOP
Length = 452
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAA 269
++ ++ M+ FSD+ W + LAK + ELG+ +AA +A V ID A
Sbjct: 14 QFGTEAMRRIFSDETTVQRWLDVEAALAKVQGELGIIPRAAADEIRRKARVELIDLGALK 73
Query: 270 EHEKRVRHDVMAHVHTLGERCPL-AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVA 446
R H ++ + + C A +H GAT+ + D+ ++ L++GLE + L
Sbjct: 74 AEMDRTAHPIVPLLRAIKRVCDGDAGEYVHWGATTQDIVDSGTVLQLRDGLEEIERDLRG 133
Query: 447 VIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
++ L A ++ ++G +H Q A T G + ++W ++ D + L + ++
Sbjct: 134 LLDNLLKLAATHRDRVMVGRSHGQQALPITFGFKVAVWAEEIRRDLQRLDQMRE 187
>UniRef50_Q6FZJ4 Cluster: Adenylosuccinate lyase; n=25;
Bacteria|Rep: Adenylosuccinate lyase - Bartonella
quintana (Rochalimaea quintana)
Length = 439
Score = 61.3 bits (142), Expect = 2e-08
Identities = 49/175 (28%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAA 269
RY+ EM +S + K+ W ++ + A +LG+ AA++ + A + D
Sbjct: 4 RYSRPEMVTIWSPKTKYRIWFEIEAHACDALAQLGIIPKEAAKVIWEKGAAAEFDVNRIN 63
Query: 270 EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
E E +HDV+A + LGE A IH G TS V D T I L ++LL + +
Sbjct: 64 EIEAITKHDVIAFLTHLGEFIGPEARFIHQGMTSSDVLDTTLNIQLMRASDILLKDIDQL 123
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
++ L A Q+K +G +H A+ TT G + +L + L A++++
Sbjct: 124 LEALKKRAFQHKETITIGRSHGIHAEPTTFGVKFALAYAEFSRCHNRLLAAREEI 178
>UniRef50_Q6D3A2 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=3; Proteobacteria|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 449
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/159 (24%), Positives = 80/159 (50%), Gaps = 2/159 (1%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVH--DIDFPAAA 269
+ + M+ F D++ + ++ I LA A+ G+ I AE+ A+ + +DF
Sbjct: 15 FGTPAMRAIFDDRELVRKYVEVEIALANAQARCGV-IPEEAAAEITASCNADTLDFELLR 73
Query: 270 EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
+ V + ++ VH + ++ + +H GAT+ + D ++ +++ L+ + A+
Sbjct: 74 HETEIVGYPILPLVHQISKQAGQSGGYVHWGATTQDIMDTAVVLQIRDAFALIEADIDAL 133
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLN 566
L A +Y++ P+ G THLQ A T G +A++WL+
Sbjct: 134 RSILARLAVRYRNTPMAGRTHLQQALPITFGYKAAIWLD 172
>UniRef50_Q5WG84 Cluster: Adenylosuccinate lyase; n=1; Bacillus
clausii KSM-K16|Rep: Adenylosuccinate lyase - Bacillus
clausii (strain KSM-K16)
Length = 457
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/163 (23%), Positives = 78/163 (47%), Gaps = 2/163 (1%)
Frame = +3
Query: 123 FSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAAEHEKRVRHDV 299
F++++K+ TW LA+A+ E GL AAQ + A + ++D K + H
Sbjct: 21 FTEKEKYKTWLLFESALAEAQAEYGLIPKKAAQEIKEAAKLENLDLEEMDRIYKEIGHGF 80
Query: 300 MAHVHTLGERCPL-AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAK 476
+ + L + CP + +H G T+ + ++ L +LK + + + +++ L A
Sbjct: 81 VPFLKVLVKACPPDSGKYVHYGITTQNIQQSSQLYILKKAHMIFMRLIGEILENLSILAS 140
Query: 477 QYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
K + G TH + A T G + S W+++L+ + ++ A+
Sbjct: 141 DNKHTVMPGRTHGRHAIPITYGYKVSAWISELISCHQRMAEAE 183
>UniRef50_Q1VP16 Cluster: Adenylosuccinate lyase; n=1; Psychroflexus
torquis ATCC 700755|Rep: Adenylosuccinate lyase -
Psychroflexus torquis ATCC 700755
Length = 295
Score = 59.3 bits (137), Expect = 7e-08
Identities = 39/122 (31%), Positives = 61/122 (50%)
Frame = +3
Query: 207 SAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGD 386
+ A IA EA + +E E RHD+MA + E A IHLGATS + D
Sbjct: 52 AVAAIANPEAVTKE----RVSEIEAETRHDIMALTKAMAEAAGEAGWCIHLGATSNDIVD 107
Query: 387 NTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLN 566
+ L++ + +L +L +I A++ + +LG TH Q A T G +A++WL+
Sbjct: 108 TAVALQLRDSMVMLRQQLCHLIGVCADVAERERDTVMLGRTHGQAAVPITFGLKAAVWLD 167
Query: 567 DL 572
+L
Sbjct: 168 EL 169
>UniRef50_Q2AIU7 Cluster: Fumarate lyase; n=1; Halothermothrix
orenii H 168|Rep: Fumarate lyase - Halothermothrix
orenii H 168
Length = 462
Score = 58.8 bits (136), Expect = 1e-07
Identities = 48/161 (29%), Positives = 79/161 (49%), Gaps = 7/161 (4%)
Frame = +3
Query: 81 PLSTRYASKEMQYN-----FSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVH 245
PL RY+ K+ +N FS++ ++ + L KA G+ S + E+E AV
Sbjct: 11 PLDHRYSLKKDLFNDLGKYFSEKATIYFQARVELALVKALAGRGV-CSFDVVKEVEEAVK 69
Query: 246 DIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAA-PIIHLGATSCYVGDNTDLIVLKNGLE 422
I E E R RH++ A V+ + ++ A P +HL ATS + D + + K E
Sbjct: 70 GIKVGEVYEEEARTRHNIRALVNCIRKKISAEARPFVHLSATSFDIVDTANSLRYKEATE 129
Query: 423 -LLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVG 542
L++P L +++Q + A+Q + +G TH Q A+ T G
Sbjct: 130 KLIVPALERLLEQWLNLAEQERDTLQIGRTHGQHAEPLTFG 170
>UniRef50_Q13PC6 Cluster: Putative lyase; n=1; Burkholderia
xenovorans LB400|Rep: Putative lyase - Burkholderia
xenovorans (strain LB400)
Length = 445
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/161 (25%), Positives = 80/161 (49%), Gaps = 2/161 (1%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVH--DIDFPAAA 269
+ + M+ FSD + + + K+ + LAK E LG+ I ++E H +ID+
Sbjct: 13 FGTDAMRTIFSDDTRVANYLKIEVALAKVEAGLGV-IPQDAWRDIEQKSHSFEIDWERFR 71
Query: 270 EHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
+ V + VM V L E C + +H G+T+ + D + ++ L+ L +L L V
Sbjct: 72 IDVEAVGYPVMPFVTQLAEHCGESGEYLHWGSTTRDITDTSFVLQLREALGVLAADLDKV 131
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
++L +++S ++ TH + A +T G R ++W +++
Sbjct: 132 RRKLREMTARHRSTLMIARTHGKHALPSTFGFRCAVWYSEV 172
>UniRef50_A1SC86 Cluster: Fumarate lyase; n=2; Nocardioides sp.
JS614|Rep: Fumarate lyase - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 450
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/170 (25%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAAE 272
+ + E++ F+D+ + +W ++ LA+A+ E+GL AA+ A V +D AE
Sbjct: 15 WGTDELRQLFNDEGRIQSWLEILAALAEAQAEVGLVPHEAARSIRAHADVKRLDLTRVAE 74
Query: 273 HEKRVRHDVMAHVHTLGERCPLAA-PIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
+ H + + L E P +A ++ GAT V D ++LK + ++L R +A
Sbjct: 75 LTRSTGHSTLGLIRCLQEILPPSAQEWVYYGATVQDVSDTWTSLMLKQ-VAIVLDRDLAR 133
Query: 450 IKQ-LGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALS 596
++Q A+ + + G TH Q T G +A++W ++L L+
Sbjct: 134 VEQATRRLAETHAGTVMCGRTHGQAGLPVTFGFKAAVWASELARHRERLA 183
>UniRef50_A4X707 Cluster: Adenylosuccinate lyase; n=3;
Actinomycetales|Rep: Adenylosuccinate lyase -
Salinispora tropica CNB-440
Length = 428
Score = 56.8 bits (131), Expect = 4e-07
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 1/154 (0%)
Frame = +3
Query: 90 TRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAA 269
+RY+ EM +SD +++TW K+ + +A+ LG + +A+++ A A
Sbjct: 3 SRYSLPEMADLWSDDARYATWSKVELLATQAQAMLG-RVPEPALADIQQA-RVPSVARVA 60
Query: 270 EHEKRVRHDVMAHVHTLGERCPL-AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVA 446
EHE++ H+++A + E P +A +HLG TS + D L ++LL +V
Sbjct: 61 EHERQRDHEILAFLAAFCENIPADSARWVHLGMTSYDLVDTALGATLARACDVLLEAVVR 120
Query: 447 VIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKR 548
+ L A + +G TH A+ TT+G +
Sbjct: 121 LRGVLVDQALAHWETVCIGRTHGMHAEPTTLGHK 154
>UniRef50_Q8ZY28 Cluster: Adenylosuccinate lyase; n=4;
Pyrobaculum|Rep: Adenylosuccinate lyase - Pyrobaculum
aerophilum
Length = 403
Score = 56.8 bits (131), Expect = 4e-07
Identities = 46/177 (25%), Positives = 90/177 (50%)
Frame = +3
Query: 78 SPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDF 257
SP RY S+E++ F+++ + + ++ L A +ELG+ +A+V +
Sbjct: 4 SPFDWRYGSEEIRRLFTNEAIINAYLEVERALVCALEELGVAERGCCEKVNKASVSADE- 62
Query: 258 PAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPR 437
E+ HD+++ V L ++ +H GATS + D ++++ L + +
Sbjct: 63 --VYRLERETGHDILSLVLLLEQKS--GCRYVHYGATSNDIIDTAWALLIRRALAAVKEK 118
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
AV QL S A++YK+L ++G TH Q A+ T+G + + + +L + R L+ A++
Sbjct: 119 ARAVGDQLASMARKYKTLEMVGRTHGQWAEPITLGFKFANYYYELYIACRQLALAEE 175
>UniRef50_Q8EVI2 Cluster: Adenylosuccinate lyase; n=1; Mycoplasma
penetrans|Rep: Adenylosuccinate lyase - Mycoplasma
penetrans
Length = 432
Score = 56.0 bits (129), Expect = 7e-07
Identities = 46/182 (25%), Positives = 87/182 (47%), Gaps = 8/182 (4%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKL------WIYLAKAEKELGLDISAAQIAELEAAVHDID 254
RY + +SD+ KF+TW K+ + Y++K E ++ +++ D
Sbjct: 4 RYEVPIISKIWSDENKFNTWLKIEKCVINYFYVSKKIDEQTFNLLNEKMS--------FD 55
Query: 255 FPAAAEHEKRVRHDVMAHVH--TLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELL 428
E EK +HDV+A + +L + IH G TS V D + ++LK L+
Sbjct: 56 LNEIYEIEKNTKHDVIAFLRAISLNIKEDSVKKWIHYGLTSTDVVDTANAVMLKETNLLI 115
Query: 429 LPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
+ + ++K+L A +YK L +G TH + T+ G + ++W ++L + L+ A+
Sbjct: 116 IEAIKNLMKELKKKAFKYKDLVQIGRTHGIHGEPTSFGYKFAIWYDELNRNLERLNLARK 175
Query: 609 DL 614
++
Sbjct: 176 EV 177
>UniRef50_A5G255 Cluster: Fumarate lyase; n=1; Acidiphilium cryptum
JF-5|Rep: Fumarate lyase - Acidiphilium cryptum (strain
JF-5)
Length = 461
Score = 56.0 bits (129), Expect = 7e-07
Identities = 44/170 (25%), Positives = 74/170 (43%), Gaps = 2/170 (1%)
Frame = +3
Query: 99 ASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELG-LDISAAQIAELEAAVHDIDFPAAAEH 275
A E+ FS Q + +W + LA + ELG + AA+ A + I A A
Sbjct: 9 APAEIAALFSRQSVWQSWLDVESALAATQAELGMIPAEAAREIAARARLETIGEAALAAD 68
Query: 276 EKRVRHDVMAHVHTLGERCP-LAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
+ R V++ V L C A +H GAT+ V +++++ L+ RL A++
Sbjct: 69 IAKTRAPVVSLVRLLSRACAGEAGGFVHWGATTQNVVQTGRVLLMRRAHAALMRRLAAIL 128
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRA 602
+L FA+ + T+++ A T G +A W+ + L E A
Sbjct: 129 DRLAGFAEAEAGTVTVARTNIRHALPITFGFKAGGWIEEFLRHEERFREA 178
>UniRef50_Q9C8F5 Cluster: Adenylosuccinate lyase-like protein;
104558-106845; n=34; cellular organisms|Rep:
Adenylosuccinate lyase-like protein; 104558-106845 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 518
Score = 56.0 bits (129), Expect = 7e-07
Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Frame = +3
Query: 276 EKRVRHDVMAHVHTLGERC---PLAAPII---HLGATSCYVGDNTDLIVLKNGLE-LLLP 434
E+ HDV A + L ++C P A ++ H TS + + + ++L+ L ++LP
Sbjct: 143 ERVTNHDVKAVEYFLKQKCESHPEIAKVLEFFHFACTSEDINNLSHALMLQEALSSVILP 202
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
+ +IK + AK + +P+L TH QPA TT+GK +++ L ++ R LS K
Sbjct: 203 TMDELIKSISLMAKSFAYVPMLSRTHGQPASPTTLGKEMAIFAVRLSVERRYLSETK 259
>UniRef50_Q9A5N7 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=3; Alphaproteobacteria|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 382
Score = 55.2 bits (127), Expect = 1e-06
Identities = 50/175 (28%), Positives = 79/175 (45%), Gaps = 2/175 (1%)
Frame = +3
Query: 99 ASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAEHE 278
++ EM FSD+ LA+A+ ++GL S A A D + AE
Sbjct: 11 STPEMLTAFSDEALLRAALTFETMLARAQADVGLIPSDAAETIAIACAELPDVVSLAEAA 70
Query: 279 KRVRHDVMAHVHTLGERC--PLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
+ V + ER P A ++H GATS + D ++ K G L+L +
Sbjct: 71 AHAGTLAIPLVALIRERIADPEVAKLVHKGATSQDLADTALMLQAKTGAALVLRDASRLA 130
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDLG 617
+ L A+++ + P+LG T LQ AQ T G +A+ WL + AL+R + + G
Sbjct: 131 QALAVLAQRHAATPMLGRTLLQAAQPITFGLKAAGWLQGV---ASALARFERETG 182
>UniRef50_Q5FNL5 Cluster: Adenylosuccinate lyase; n=62;
Bacteria|Rep: Adenylosuccinate lyase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 443
Score = 54.4 bits (125), Expect = 2e-06
Identities = 48/181 (26%), Positives = 82/181 (45%), Gaps = 7/181 (3%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDI---SAAQIAE----LEAAVHDI 251
RY+ +M +S +F W ++ +A + G DI SA I E AA D
Sbjct: 4 RYSRPQMTAIWSPANRFRIWFEIEALACEAMAKRG-DIPAESAKTIREKGDAAMAAFSDA 62
Query: 252 DFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLL 431
D E E RHDV+A + L E+ + +HLG TS V D + + +LLL
Sbjct: 63 DLARIDEIEAETRHDVIAFLTWLAEKIGPDSRFVHLGMTSSDVLDTCLSVQMTQAADLLL 122
Query: 432 PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDD 611
L V+ L + A ++++ +G +H A+ T+ G + + + + L +A+ +
Sbjct: 123 EDLDRVLAALKARAYEHRNTVTIGRSHAIHAEPTSFGLKIAGHYAEFARNRERLIQARKE 182
Query: 612 L 614
+
Sbjct: 183 I 183
>UniRef50_Q7MJB9 Cluster: Adenylosuccinate lyase; n=3;
Gammaproteobacteria|Rep: Adenylosuccinate lyase - Vibrio
vulnificus (strain YJ016)
Length = 459
Score = 53.6 bits (123), Expect = 4e-06
Identities = 44/164 (26%), Positives = 77/164 (46%), Gaps = 2/164 (1%)
Frame = +3
Query: 87 STRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPA 263
S + K+M+ +SD+ TW +A+A+ ELGL SAA + + +D+
Sbjct: 22 SPLFTQKQMKQVWSDENLIRTWLTFETKIAEAQAELGLIPHSAASAIKQVCDIRHLDWAR 81
Query: 264 AAEHEKRVRHDVMAHVHTLGERC-PLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRL 440
A+ + V + V L E+ +H G T+ + D + + LK L ++ +L
Sbjct: 82 LAQDTQTVGMAIKPLVDQLSEQGNDEVKQYLHWGCTTQDLLDTSLAMRLKQTLHIVRQQL 141
Query: 441 VAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
VA+ QL S A +K ++ T+ A TT G + S +L ++
Sbjct: 142 VALGDQLASMALHHKRTVMVARTNAMDALPTTWGLQVSGYLQEI 185
>UniRef50_Q6MLQ8 Cluster: PurB protein; n=1; Bdellovibrio
bacteriovorus|Rep: PurB protein - Bdellovibrio
bacteriovorus
Length = 418
Score = 53.2 bits (122), Expect = 5e-06
Identities = 40/159 (25%), Positives = 74/159 (46%)
Frame = +3
Query: 138 KFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHT 317
KF ++ I +A+ + +LG I A++ A + +E E+ +HDV+A V
Sbjct: 10 KFGKMMEVEIAVAQVQSQLG--IIPKNAAKIIAQKARFNVKRISEIERETKHDVIAFVSN 67
Query: 318 LGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPI 497
L E IH G TS V D + ++ +L+ +VA+ K L + ++
Sbjct: 68 LAENVGPQGKFIHYGMTSSDVLDTAFSLQVREAGVVLMKSIVALEKSLKTLVTKHAETLC 127
Query: 498 LGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
G TH A+ TT G + + +L + +++ + A D++
Sbjct: 128 AGRTHGMFAEPTTFGFKMAGFLAEAQRNKKRVKAALDNM 166
>UniRef50_Q0SJY5 Cluster: Probable adenylosuccinate lyase; n=1;
Rhodococcus sp. RHA1|Rep: Probable adenylosuccinate
lyase - Rhodococcus sp. (strain RHA1)
Length = 493
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/173 (21%), Positives = 77/173 (44%), Gaps = 2/173 (1%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAAE 272
+ + E + F ++ W + LA+ + ELG+ AAQ D +
Sbjct: 49 FGNAEQRAIFDGPQRLQGWLDVERALAQTQAELGIIPAEAAQRISAHCQSDLFDINKLRQ 108
Query: 273 HEKRVRHDVMAHVHTLGERCPLA-APIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
H +H ++ V+ L + +H GATS + D+ + L+ L+ + + A
Sbjct: 109 HVNATQHPIVPMVNALEKLVGTEFGQFVHYGATSQDIMDSGQALQLRQSLQGIERDVAAA 168
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
K S A ++++ +G TH Q A + G +A+ W+++L + ++ ++D
Sbjct: 169 TKAAASLALKHRNTTQVGRTHGQHAVPISFGLKAATWVDELQRLQTRIAESRD 221
>UniRef50_A5G1E3 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=1; Acidiphilium cryptum JF-5|Rep:
3-carboxy-cis,cis-muconate cycloisomerase - Acidiphilium
cryptum (strain JF-5)
Length = 450
Score = 52.8 bits (121), Expect = 6e-06
Identities = 52/175 (29%), Positives = 75/175 (42%), Gaps = 1/175 (0%)
Frame = +3
Query: 78 SPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDF 257
+P A+ M+ FS + + + LA+A GL + A A A +
Sbjct: 69 APAEIMAATASMRRLFSARAGIAAMLRAEAALARAGAAAGLITAEAATAIEAACAGEKPD 128
Query: 258 PAA-AEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLP 434
PAA AE R V+ V L P A IH G T+ + D ++ L++G LL
Sbjct: 129 PAALAEAGARAGTIVIPLVAWLRAAVPAHAAAIHRGGTTQDIVDTGLILQLRDGFLLLEA 188
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSR 599
L A A+ + + P++ T LQPA T G +A+ WL L D RA R
Sbjct: 189 DLDAAAAAAARLARAHAATPMIARTLLQPALPATFGLKAAQWL-AALDDARAALR 242
>UniRef50_O49514 Cluster: Adenylosuccinate lyase - like protein;
n=2; Viridiplantae|Rep: Adenylosuccinate lyase - like
protein - Arabidopsis thaliana (Mouse-ear cress)
Length = 467
Score = 52.4 bits (120), Expect = 8e-06
Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Frame = +3
Query: 276 EKRVRHDVMAHVHTLGERC---PLAAPII---HLGATSCYVGDNTDLIVLKNGLE-LLLP 434
E+ HDV A + L ++C P A ++ H TS + + + ++L+ L ++LP
Sbjct: 152 ERVTNHDVKAVEYFLKQKCESQPEIAKVLEFFHFACTSEDINNLSHALMLQEALSSVILP 211
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
+ +IK + AK + +P+L TH QPA TT+GK + + L + R LS K
Sbjct: 212 TMDELIKSISLIAKNFAYVPMLSRTHGQPATPTTLGKEMANFAVRLSEERRYLSETK 268
>UniRef50_A3XE63 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=2; Rhodobacteraceae|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Roseobacter sp. MED193
Length = 353
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/91 (32%), Positives = 45/91 (49%)
Frame = +3
Query: 342 APIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQP 521
A IH GATS V D ++ N L+ L RL ++ +L + + LP++ T +Q
Sbjct: 97 ASAIHTGATSQDVIDTAMVLTCLNVLDELEDRLATLVDRLETLLDASRDLPLMARTRMQA 156
Query: 522 AQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
A TVG R S WL L+ + + + DL
Sbjct: 157 AVPATVGLRVSSWLRPLVDHQSRIQALRQDL 187
>UniRef50_Q9HS42 Cluster: Adenylosuccinate lyase; n=4;
Halobacteriaceae|Rep: Adenylosuccinate lyase -
Halobacterium salinarium (Halobacterium halobium)
Length = 495
Score = 51.2 bits (117), Expect = 2e-05
Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +3
Query: 291 HDVMAHVHTLGERCPLAAPI-IHLGATSCYVGDNTDLIVLKNGLELLL-PRLVAVIKQLG 464
HDV A + L E P A IH G TS V + +++ + +L P L + L
Sbjct: 134 HDVKAVEYFLREHAPARAHSWIHFGLTSEDVNNLAYRLLVDGAITAVLTPELRGLRDDLV 193
Query: 465 SFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKD 608
SFA Y LP+L TH QPA TT GK +++ L RAL+R D
Sbjct: 194 SFAHDYADLPMLARTHGQPATPTTFGKEMAVYAARL---GRALARITD 238
>UniRef50_A3JVW8 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=4; Rhodobacterales|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Rhodobacterales bacterium HTCC2150
Length = 447
Score = 50.4 bits (115), Expect = 3e-05
Identities = 47/151 (31%), Positives = 67/151 (44%), Gaps = 3/151 (1%)
Frame = +3
Query: 171 LAKAEKELGLDISAAQIAELEAAVHDIDFPAA-AEHEKRVRHDVMAHVHTLGE--RCPLA 341
LAKA+ LG+ A A AA+ I PA A R V A V E + P
Sbjct: 40 LAKAQGALGVIPETAAAAINGAAMEVIIDPAGLAAQTGRSAVPVPALVAAFREAMQAPDH 99
Query: 342 APIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQP 521
A IH GATS + + + L+ + + RL +++ LG+ AK + PI T+ Q
Sbjct: 100 AKFIHFGATSQDIMETGQNLRLRQVINIFSQRLNTLVQSLGNLAKAHAETPIAARTYSQI 159
Query: 522 AQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
A T+ G + W N L L K++L
Sbjct: 160 ATPTSFGAIVASWGNPHLRHIERLVLVKENL 190
>UniRef50_Q3E4V0 Cluster: Adenylosuccinate lyase; n=3; Chloroflexi
(class)|Rep: Adenylosuccinate lyase - Chloroflexus
aurantiacus J-10-fl
Length = 466
Score = 49.6 bits (113), Expect = 6e-05
Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 6/111 (5%)
Frame = +3
Query: 246 DIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAA-----PIIHLGATSCYVGDNTDLIVLK 410
D D A A ++RV HDV A + L ER +H TS V + +++K
Sbjct: 79 DDDALAIAAWDRRVNHDVKAVEYWLRERLTTLGLTGHLEAVHFALTSEDVNNLAYALMVK 138
Query: 411 NGLEL-LLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLW 560
E+ LLP L ++++++ A + + P+L TH QPA TT GK +++
Sbjct: 139 EAREMVLLPALESLLERIRQLADEEAATPMLARTHGQPATPTTFGKEMNVF 189
>UniRef50_P44797 Cluster: Adenylosuccinate lyase; n=32;
Gammaproteobacteria|Rep: Adenylosuccinate lyase -
Haemophilus influenzae
Length = 456
Score = 49.6 bits (113), Expect = 6e-05
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Frame = +3
Query: 234 AAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCP------LAAPIIHLGATSCYVGDNTD 395
A ++ D E E+ HDV A + L E+ + IH TS + + +
Sbjct: 72 ANFNEADAARIKEIERTTNHDVKAVEYFLKEKIQNEVELVKVSEFIHFACTSEDINNLSH 131
Query: 396 LIVLKNGL-ELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGK 545
++L E++LP +I ++ A++YK++P+L TH QPA +TVGK
Sbjct: 132 ALMLSTARDEVILPEWQKLIDEITRLAEEYKTIPLLSRTHGQPASPSTVGK 182
>UniRef50_A7D364 Cluster: Adenylosuccinate lyase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Adenylosuccinate lyase -
Halorubrum lacusprofundi ATCC 49239
Length = 525
Score = 49.2 bits (112), Expect = 8e-05
Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 1/123 (0%)
Frame = +3
Query: 234 AAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKN 413
A HD+ A E+ RVR D + T+ + L P IH G TS V + +++K
Sbjct: 148 ATNHDVK---AVEYFLRVRLDGLDDSGTIADSEALY-PWIHFGLTSEDVNNLAQRLLVKQ 203
Query: 414 GL-ELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERA 590
+ E ++P + V L A++++ P+L TH QPA TT GK +++ + L RA
Sbjct: 204 AVSEAIVPAIREVRDALVDLAQEHRGTPMLAHTHGQPATPTTFGKEMAVYASRL---GRA 260
Query: 591 LSR 599
L R
Sbjct: 261 LGR 263
>UniRef50_Q1AVN7 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=2; Actinobacteria (class)|Rep:
3-carboxy-cis,cis-muconate cycloisomerase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 448
Score = 48.8 bits (111), Expect = 1e-04
Identities = 36/122 (29%), Positives = 56/122 (45%), Gaps = 1/122 (0%)
Frame = +3
Query: 246 DIDFPAAAEHEKRVRHDVMAHVHTLGERCP-LAAPIIHLGATSCYVGDNTDLIVLKNGLE 422
++D E + + V A V L P AA +H GATS + D +++ + L
Sbjct: 61 ELDPEELGERGRAAGNPVPALVKELTAAVPGEAARHVHRGATSQDITDTAAMLISREALG 120
Query: 423 LLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRA 602
L+L L V A++++ + G T LQ A TT G +A+ WL L R L A
Sbjct: 121 LILRELDGVCAACARLAEEHRETLVAGRTLLQQALPTTFGLKAAGWLVAALEARRVLREA 180
Query: 603 KD 608
++
Sbjct: 181 RE 182
>UniRef50_A1B7S2 Cluster: Fumarate lyase; n=2; Paracoccus
denitrificans PD1222|Rep: Fumarate lyase - Paracoccus
denitrificans (strain Pd 1222)
Length = 433
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELG-LDISAAQIAELEAAVHDIDFPAAAE 272
Y EM SD+ ++ + LA+A+ +LG + +AA++ A D D A
Sbjct: 11 YGDDEMAAILSDRSAILAMLRVEVALARAQADLGAIPAAAAEVIAKAAEALDPDPAELAA 70
Query: 273 HEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
R + L A H GATS + D + L L+LL RL +
Sbjct: 71 AVARAGITAQPVIAALKSAAGEAGAFAHYGATSQDIVDTALALQLVAALDLLGGRLDRLT 130
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLW 560
L A + LPI T Q A TT+G + ++W
Sbjct: 131 ALLVQKAADHADLPIPARTRHQIAAPTTLGAKIAVW 166
>UniRef50_Q9XAN2 Cluster: Putative 3-carboxy-cis,cis-muconate
cycloisomerase; n=3; Streptomyces|Rep: Putative
3-carboxy-cis,cis-muconate cycloisomerase - Streptomyces
coelicolor
Length = 454
Score = 47.6 bits (108), Expect = 2e-04
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +3
Query: 345 PIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPA 524
P +H GATS + D ++V L+LLLP L + L A +++ P+ G T Q A
Sbjct: 111 PYVHRGATSQDILDTATMLVAARTLDLLLPDLARTERALARLAAEHRDTPMPGRTLTQHA 170
Query: 525 QLTTVGKRASLWLNDLLMDER 587
T G +A+ W L++D R
Sbjct: 171 VPTVFGLKAAGW-RALVLDAR 190
>UniRef50_Q9HY92 Cluster: Probable lyase; n=7; Pseudomonas
aeruginosa|Rep: Probable lyase - Pseudomonas aeruginosa
Length = 477
Score = 47.2 bits (107), Expect = 3e-04
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 2/161 (1%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELG-LDISAAQIAELEAAVHDIDFPAAAE 272
Y+S FSD + W + LA + E+G + AA+ + A V D
Sbjct: 15 YSSPAFAAIFSDTNQVRRWLDVERALAATQAEMGIIPHEAAREIDRAAQVERFDLTQLGR 74
Query: 273 HEKRVRHDVMAHVHTLGERCPLA-APIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAV 449
H ++ + L C + +H G T+ + D ++ +K L L ++
Sbjct: 75 ESLETGHLLVPTIRALARSCEGSWGEYVHYGVTTQDILDTGLMLQVKEAWGHALGLLHSI 134
Query: 450 IKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
L + A +++ P++ TH Q A TT G + ++W++++
Sbjct: 135 RGHLLALALRHQHTPMVARTHGQQALPTTFGYKVAVWVDEI 175
>UniRef50_Q2J4S4 Cluster: Adenylosuccinate lyase; n=4;
Actinomycetales|Rep: Adenylosuccinate lyase - Frankia
sp. (strain CcI3)
Length = 435
Score = 47.2 bits (107), Expect = 3e-04
Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 2/156 (1%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RY EM +S+ K+ W ++ + + +A G I A I + AA A AE
Sbjct: 4 RYTLAEMGRVWSEAHKYELWCRVEVLVMEAHAAAGR-IPADSIEPVRAAPAPTP-EAVAE 61
Query: 273 HEKRVRHDVMAHVHTLGERCP--LAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVA 446
E +HDV+A + +R AA +H G TS + D + L +LLL R
Sbjct: 62 VEAVTQHDVIAFLTAWADRTEPRSAAAYVHFGMTSSDLLDTALALQLVESTDLLLARADI 121
Query: 447 VIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRAS 554
++ L +++ +G TH + T G R +
Sbjct: 122 LVAALRDLGLAHRNTLRVGRTHGIHGEPTVFGHRVA 157
>UniRef50_Q1YSL1 Cluster: Adenylosuccinate lyase; n=1; gamma
proteobacterium HTCC2207|Rep: Adenylosuccinate lyase -
gamma proteobacterium HTCC2207
Length = 475
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 3/169 (1%)
Frame = +3
Query: 72 YRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL--DISAAQIAELEAAVH 245
+ P A + + FS Q + + LA+ + +L + D +A ++ +A V
Sbjct: 22 FADPNEGARAKQRVAEIFSRQYQVQRLLDIEAALARVQADLNIIPDWAAEELTR-KAQVS 80
Query: 246 DIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAP-IIHLGATSCYVGDNTDLIVLKNGLE 422
++ E RVRH +++ ++ A +H GAT+ + + ++ L +
Sbjct: 81 NVPLDQLKEERARVRHSMVSLLNIWQHSIEGGAEEYMHYGATTVDIFNTAMVLQLYDASA 140
Query: 423 LLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLND 569
+LL +L + + A +YK+ P++G T Q A T GK+ S WL +
Sbjct: 141 VLLDQLRLLENIMIGLADEYKATPMIGRTLGQHALPITFGKKVSSWLGE 189
>UniRef50_Q02CF9 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=1; Solibacter usitatus Ellin6076|Rep:
3-carboxy-cis,cis-muconate cycloisomerase - Solibacter
usitatus (strain Ellin6076)
Length = 427
Score = 47.2 bits (107), Expect = 3e-04
Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 5/159 (3%)
Frame = +3
Query: 99 ASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHD-IDFPAAAEH 275
A++ M FSD LA+AE G+ ++A A AA+ + D
Sbjct: 12 ATEAMSKVFSDTSVLQAMLDFEAALARAEARCGVIPASAVTAIAAAAIAEGFDLSELTRL 71
Query: 276 EKRVRHDVMAHVHTLGERC----PLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLV 443
R + V L R P+AA +H GATS V D +++L+ + +L
Sbjct: 72 SLRAGTPAIPLVKMLTARVRAIDPVAAGFVHWGATSQDVADTALVLLLRQAVPILQADHE 131
Query: 444 AVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLW 560
+ L +++ +LG T LQPA T G +A+ W
Sbjct: 132 RTMAALHGLSERNAGAVMLGRTLLQPASPVTFGLKAAGW 170
>UniRef50_A7IQF6 Cluster: Fumarate lyase; n=3; Xanthobacter
autotrophicus Py2|Rep: Fumarate lyase - Xanthobacter sp.
(strain Py2)
Length = 456
Score = 47.2 bits (107), Expect = 3e-04
Identities = 45/164 (27%), Positives = 72/164 (43%), Gaps = 5/164 (3%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL--DISAAQI-AELEAAVHDIDFPAA 266
+++ E+Q F D + W L LA+ E E GL + SAA I A V D DF A
Sbjct: 15 WSTPELQALFDDAPRTRRWLDLLGTLAEVEGEFGLIPETSAAAIVAACRDVVLDDDFFAR 74
Query: 267 -AEHEKRVRHDVMAHVHTLGERCP-LAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRL 440
A + H + + +R P + + GAT + D+ ++VL L+L L
Sbjct: 75 FAAGYRATGHSTAGLIDVIRQRYPESVSEWFYFGATVQDITDSWLMLVLGEARALILADL 134
Query: 441 VAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDL 572
I + + ++ ++G TH Q T G + + WL +L
Sbjct: 135 DRSIAAATALCRAHRDTVMVGRTHGQQGLPITFGFKVAGWLAEL 178
>UniRef50_A3H8P9 Cluster: Adenylosuccinate lyase; n=1; Caldivirga
maquilingensis IC-167|Rep: Adenylosuccinate lyase -
Caldivirga maquilingensis IC-167
Length = 470
Score = 47.2 bits (107), Expect = 3e-04
Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 6/96 (6%)
Frame = +3
Query: 276 EKRVRHDVMAHVHTLGERCPLA-----APIIHLGATSCYVGDNTDLIVLKNGL-ELLLPR 437
E + HDV A + L R A +IHLG TS V + I++K L E L+P
Sbjct: 80 EDELGHDVKALEYVLRGRLKAIGLEDYAHLIHLGLTSEDVNNLAMGIMIKRILYEYLIPS 139
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGK 545
LV + K L + + +Y P+L TH QPA TT GK
Sbjct: 140 LVDLGKVLVNLSNKYADTPMLARTHGQPATPTTFGK 175
>UniRef50_P56468 Cluster: Adenylosuccinate lyase; n=47;
Bacteria|Rep: Adenylosuccinate lyase - Helicobacter
pylori (Campylobacter pylori)
Length = 440
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/167 (22%), Positives = 80/167 (47%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RYA++EM+ +++Q KF T+ ++ + +A +LG I + ++ A + E
Sbjct: 4 RYANEEMKALWNEQTKFETYLEVEKAVVRAWNKLG-QIQDSDCEKI-CAKAAFNLERIKE 61
Query: 273 HEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
EK +HD++A + E + H G TS D +++ L+L+ + +
Sbjct: 62 IEKTTKHDLIAFTTCVAESLGEESRFFHYGITSSDCIDTAMALLMTKSLKLIQKGVKNLY 121
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERAL 593
+ L + A ++K ++G +H + T G +L+ +++ +AL
Sbjct: 122 ETLKNRALEHKDTLMVGRSHGVFGEPITFGLVLALFADEIKRHLKAL 168
>UniRef50_Q5LKE9 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=7; Rhodobacteraceae|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Silicibacter pomeroyi
Length = 445
Score = 46.8 bits (106), Expect = 4e-04
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +3
Query: 171 LAKAEKELGLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAP- 347
LAKA+ LGL I + A +I A E + V R + AP
Sbjct: 40 LAKAQGALGL-IPVESAGAIHRAAMEIHLDPGALAEATGANGVSVPALVAAFRSEMQAPE 98
Query: 348 ---IIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQ 518
+H GATS + D ++ L+ + +L L AV++ L + A+ + LP+ G ++ Q
Sbjct: 99 HAQYVHWGATSQDIIDTGLMLRLRQAVSVLERDLAAVLETLAALAESHADLPMAGRSYAQ 158
Query: 519 PAQLTTVGKRASLW---LNDLLMDERALSR 599
A T+ G + W L DLL + L R
Sbjct: 159 HATPTSFGAVVASWGAPLLDLLRELPGLRR 188
>UniRef50_Q83FF1 Cluster: Adenylosuccinate lyase; n=2; Tropheryma
whipplei|Rep: Adenylosuccinate lyase - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 481
Score = 46.4 bits (105), Expect = 6e-04
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 141 FSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDI--DFPAAAEHEKRVRHDVMAHVH 314
F WRK LA+ KE L + VHD + P + E+R++HDV A
Sbjct: 45 FFLWRKAVFGLAEPTKE--------DERFLSSIVHDAHKNIPRVKKIEERIQHDVKAVEI 96
Query: 315 TLGERCPLAA-----PIIHLGATSCYVGDNTDLIVLKNGL-ELLLPRLVAVIKQLGSFAK 476
L ER ++H TS + + + +K L E++LP + +I L ++
Sbjct: 97 FLRERFTQQGLGNIVELLHFACTSEDINNLAYALNMKAALSEVILPSIDELIGHLEKMSQ 156
Query: 477 QYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERAL 593
+Y +L TH QPA TT+GK +++ L + L
Sbjct: 157 KYAGDAMLARTHGQPATPTTLGKELLVFVYRLKRQRKNL 195
>UniRef50_Q73MK9 Cluster: Adenylosuccinate lyase, putative; n=1;
Treponema denticola|Rep: Adenylosuccinate lyase,
putative - Treponema denticola
Length = 480
Score = 46.4 bits (105), Expect = 6e-04
Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 6/116 (5%)
Frame = +3
Query: 225 ELEAAVHDI----DFPAAAEHEKRVRHDVMAHVHTLGERCPL-AAPIIHLGATSCYVGDN 389
ELE + DI D E E + +H++ A V+ L ++ P AP++HLGATS + D
Sbjct: 70 ELEKTLDDIALNIDPSEVYEEEHKTQHNIRALVNVLKKKVPENTAPLVHLGATSADILDT 129
Query: 390 TDLIVLKNG-LELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRAS 554
+ +++ +++++P L L A++ P +G TH Q A T G S
Sbjct: 130 AFSMRIRDAVIKVIIPLLKKTELLLCDIAEREAETPQVGRTHGQHAVPITFGYAVS 185
>UniRef50_Q9I6Q8 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=67; Proteobacteria|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Pseudomonas aeruginosa
Length = 459
Score = 46.4 bits (105), Expect = 6e-04
Identities = 48/179 (26%), Positives = 77/179 (43%), Gaps = 6/179 (3%)
Frame = +3
Query: 96 YASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHD--IDFPAAA 269
+ + M+ FSD+ + LA+AE G+ + A +A +EAA D A A
Sbjct: 14 FMAAPMRAVFSDRGRLQGMLDFEAALARAEARTGV-VPATAVAPIEAACRAELYDPLALA 72
Query: 270 EHEKRVRHDVMAHVHTLGERCPL----AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPR 437
E + + V LG + A +HLGATS D+ ++ L+ L LL
Sbjct: 73 EAVATAGNSAIPLVKALGRQVAAGDAEAERYVHLGATSQDAMDSGLVLQLRRALALLEQD 132
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
L + + L A+++ P+ G T LQ A T+G + + L L + L + L
Sbjct: 133 LQRLAEVLADQAERHADTPLAGRTWLQHATPVTLGMKLAGLLGALTRHRQRLRELRPRL 191
>UniRef50_A0HE34 Cluster: Fumarate lyase; n=2; Comamonadaceae|Rep:
Fumarate lyase - Comamonas testosteroni KF-1
Length = 469
Score = 46.0 bits (104), Expect = 7e-04
Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 5/149 (3%)
Frame = +3
Query: 123 FSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAAEHEKRVRHDV 299
FSD + + LA+A+ + GL AAQ +D AE +
Sbjct: 17 FSDAQWLQALLRFESGLARAQADCGLIPEPAAQAIASACEQAPLDRDRIAEQARASGALG 76
Query: 300 MAHVHTLGE----RCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGS 467
+A V L + P P +H GAT+ D ++ + L+ LL L A++ L +
Sbjct: 77 LALVKPLQQWLQAHGPQGLPWLHWGATTQDAVDTASALLTQQALQALLAELQALVDALLN 136
Query: 468 FAKQYKSLPILGFTHLQPAQLTTVGKRAS 554
A ++ + P+L + LQPAQ+T+ G + +
Sbjct: 137 LAARHAATPMLARSLLQPAQITSFGLKCA 165
>UniRef50_Q8G3G1 Cluster: Adenylosuccinate lyase; n=9;
Actinobacteria (class)|Rep: Adenylosuccinate lyase -
Bifidobacterium longum
Length = 481
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/73 (30%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Frame = +3
Query: 348 IIHLGATSCYVGDNTDLIVLKNGLE-LLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPA 524
++H TS + + + +KN +E + P +I L A+++K +P+L TH QPA
Sbjct: 134 LVHFACTSEDINNLSIARCVKNAMENVWTPEFKRIIDHLAGKAEEFKDMPLLSLTHGQPA 193
Query: 525 QLTTVGKRASLWL 563
TT+GK ++++
Sbjct: 194 TPTTLGKELAVYV 206
>UniRef50_P0AB90 Cluster: Adenylosuccinate lyase; n=215; cellular
organisms|Rep: Adenylosuccinate lyase - Escherichia coli
O6
Length = 456
Score = 45.2 bits (102), Expect = 0.001
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
Frame = +3
Query: 276 EKRVRHDVMAHVHTLGERCP------LAAPIIHLGATSCYVGDNTDLIVLKNGL-ELLLP 434
E+ HDV A + L E+ + IH TS + + + ++LK E++LP
Sbjct: 86 ERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILP 145
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGK 545
+I + A QY+ +P+L TH QPA +T+GK
Sbjct: 146 YWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTIGK 182
>UniRef50_Q12CF4 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=2; Polaromonas|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 419
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 99 ASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISA-AQIAELEAAVHDIDFPAAAEH 275
++ E+ FS++ + LA+A+ +GL A AQ V D
Sbjct: 10 STSEILEAFSERNFLDAMLRFEGSLARAQASVGLIPEAVAQSISGTCKVELFDVAKIVRE 69
Query: 276 EKRVRHDVMAHVHTLGERCPL----AAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLV 443
R + V +L E L AA +H G+TS V D +V +N L L+ +
Sbjct: 70 SGRAGSIAIPLVKSLKETVGLFNKDAAGFVHFGSTSQDVIDTALALVTRNALNLIEADVH 129
Query: 444 AVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDLG 617
+ L A ++ + P+L T +QPA +T+ G + + W L+ R+L R + G
Sbjct: 130 KAVAALLVLAGRHAADPVLARTLMQPASVTSFGLKCAGWAAPLV---RSLQRLQATAG 184
>UniRef50_A6WG20 Cluster: Adenylosuccinate lyase; n=2; Bacteria|Rep:
Adenylosuccinate lyase - Kineococcus radiotolerans
SRS30216
Length = 470
Score = 44.4 bits (100), Expect = 0.002
Identities = 33/118 (27%), Positives = 62/118 (52%), Gaps = 6/118 (5%)
Frame = +3
Query: 270 EHEKRVRHDVMAHVHTLGERCP---LA--APIIHLGATSCYVGDNTDLIVLKNGL-ELLL 431
E E+ HDV A + + R LA A + HL ATS + + + +++++ + E+ L
Sbjct: 97 EIERVTVHDVKAVEYWIKRRLEGTSLADVAELTHLFATSEDINNLSYALMVRDAVGEVWL 156
Query: 432 PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK 605
P ++ + A++ + LP+L TH QPA TT+GK ++ + L + ++ A+
Sbjct: 157 PAATGLVDDVARMARELRDLPMLSRTHGQPATPTTLGKELAVLAHRLRRQLKRIAAAE 214
>UniRef50_A1A0V2 Cluster: Adenylosuccinate lyase; n=3;
Actinobacteridae|Rep: Adenylosuccinate lyase -
Bifidobacterium adolescentis (strain ATCC 15703 / DSM
20083)
Length = 480
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 3/149 (2%)
Frame = +3
Query: 168 YLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAA- 344
YL + G + AQ A EA H D A E + + LG L
Sbjct: 76 YLRSIPENFGAE-GIAQHAAYEAKTHH-DVKAV---EYYIDDQLEKAADVLGHDTQLTGL 130
Query: 345 -PIIHLGATSCYVGDNTDLIVLKNGLELL-LPRLVAVIKQLGSFAKQYKSLPILGFTHLQ 518
++H TS + + + +KNG+E + LP A++ L A Y+ +L TH Q
Sbjct: 131 KTLVHFACTSEDINNLSIARCVKNGVEQVWLPAAQAIVDHLAQKADAYRDKAMLSLTHGQ 190
Query: 519 PAQLTTVGKRASLWLNDLLMDERALSRAK 605
PA TT+GK ++++ L R L++ K
Sbjct: 191 PATPTTLGKELAVYVYRL---NRQLNKVK 216
>UniRef50_A7AM59 Cluster: Adenylosuccinate lyase, putative; n=1;
Babesia bovis|Rep: Adenylosuccinate lyase, putative -
Babesia bovis
Length = 477
Score = 44.0 bits (99), Expect = 0.003
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 18/192 (9%)
Frame = +3
Query: 51 QNTEYCNYRSPLSTRYASKEM-------QYNFSDQKKFS--TWRKLWIYLAKAEKELGLD 203
Q ++ SPL TRY + +Y S + F +W + + +
Sbjct: 4 QRDSIVHFVSPLDTRYRNSSSAIGEHLSEYALSRNRIFVEVSWLRFLVSEGLTNVTKLDE 63
Query: 204 ISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAA--------PIIHL 359
S A ++E+ D D + +KRV HDV A + + ++ + P +H+
Sbjct: 64 SSDAYLSEICNFKPD-DMGSITAIDKRVNHDVKATEYYIRDKLKSSGLPQLISLEPWVHM 122
Query: 360 GATSCYVGDNTDLIVLKNGLELLL-PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTT 536
TS + + +++ +E ++ P ++ +I+ + +FA + P+L TH QPA TT
Sbjct: 123 FCTSEDINSPAYSMGIRDCIEKVIKPTILRIIETVATFATENAGKPMLSRTHGQPASPTT 182
Query: 537 VGKRASLWLNDL 572
GK +++++ L
Sbjct: 183 FGKEFAVYVHRL 194
>UniRef50_Q8NN17 Cluster: Adenylosuccinate lyase; n=3;
Corynebacterium|Rep: Adenylosuccinate lyase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 372
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/71 (32%), Positives = 39/71 (54%)
Frame = +3
Query: 351 IHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQL 530
IH+GATS + D+ ++ +K G+ ++ +L + + L ++K+ PI+G T Q A
Sbjct: 96 IHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATP 155
Query: 531 TTVGKRASLWL 563
TT G WL
Sbjct: 156 TTFGALTGGWL 166
>UniRef50_Q6D4E7 Cluster: Adenylosuccinate lyase; n=36;
Proteobacteria|Rep: Adenylosuccinate lyase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 456
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
Frame = +3
Query: 276 EKRVRHDVMAHVHTLGERCPLAAPI------IHLGATSCYVGDNTDLIVLKNGL-ELLLP 434
E HDV A + L E+ + IH TS + + + ++L +++LP
Sbjct: 86 EHTTNHDVKAVEYFLKEKVAAIPALHAVNEFIHFACTSEDINNLSHALMLDTARRDVILP 145
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGK 545
+I L + A++Y+ +P+L TH QPA +T+GK
Sbjct: 146 HWRQIIDALKTLAQEYRDIPLLSRTHGQPATPSTIGK 182
>UniRef50_A4EGL0 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=1; Roseobacter sp. CCS2|Rep:
3-carboxy-cis,cis-muconate cycloisomerase - Roseobacter
sp. CCS2
Length = 347
Score = 42.3 bits (95), Expect = 0.009
Identities = 37/122 (30%), Positives = 53/122 (43%)
Frame = +3
Query: 195 GLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSC 374
G+D S A +EAA D A E V ++ + R P A +H G TS
Sbjct: 48 GIDASDHIAASIEAAQIDPQALKAGMTEDGVPIPILVRLLRKHLR-PDQATHVHQGLTSQ 106
Query: 375 YVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRAS 554
V D + ++ L L LL RL + + L + + + I FT +QPA TTV +
Sbjct: 107 DVVDTSLILALVQVLSLLKERLGLLDQHLAEKQRAFGNRSITAFTRMQPAMETTVHEVID 166
Query: 555 LW 560
W
Sbjct: 167 RW 168
>UniRef50_A3VZD3 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=3; Rhodobacteraceae|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Roseovarius sp. 217
Length = 357
Score = 41.9 bits (94), Expect = 0.012
Identities = 27/86 (31%), Positives = 40/86 (46%)
Frame = +3
Query: 351 IHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQL 530
+H GATS V D + L+ +LL RL ++ L ++ S P++G T +Q A
Sbjct: 99 VHQGATSQDVLDTALALTLQATTKLLDHRLASLQSALADLDTRFGSNPLMGRTRMQAAMP 158
Query: 531 TTVGKRASLWLNDLLMDERALSRAKD 608
V R W+ L L+RA D
Sbjct: 159 IRVTDRLRPWITPLTTHRSRLARATD 184
>UniRef50_Q59092 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=2; Acinetobacter|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Acinetobacter sp. (strain ADP1)
Length = 451
Score = 41.5 bits (93), Expect = 0.016
Identities = 42/160 (26%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = +3
Query: 123 FSDQKKFSTWRKLWIYLAKAEKELG-LDISAAQIAELEA--AVHDIDFPAAAEHEKRVRH 293
FSD+ S + + LA+A+ ++G + SAA + E A A+ IDF A A +
Sbjct: 18 FSDRALVSYMVEAEVALAQAQAQVGVIPQSAATVIERAAKTAIDKIDFDALATATGLAGN 77
Query: 294 DVMAHVHTLG----ERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQL 461
+ V L + AA +H GATS + D ++ ++ L ++ ++ +
Sbjct: 78 IAIPFVKQLTAIVKDADEDAARYVHWGATSQDILDTACILQCRDALAIVQNQVQQCYETA 137
Query: 462 GSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMD 581
S A+ Y+ ++G T LQ A T+G + + W + D
Sbjct: 138 LSQAQTYRHQVMMGRTWLQQALPITLGHKLARWASAFKRD 177
>UniRef50_Q9U0T7 Cluster: Adenylosuccinate lyase; n=36; cellular
organisms|Rep: Adenylosuccinate lyase - Leishmania major
Length = 479
Score = 40.3 bits (90), Expect = 0.036
Identities = 51/201 (25%), Positives = 87/201 (43%), Gaps = 18/201 (8%)
Frame = +3
Query: 24 TTIDAPVELQNTEYCNYRSPLSTRYA--SKEMQYNFSDQKKFSTWRKLWI-YLAKAEKEL 194
T AP E+ SPL RY + ++ FS+ F ++ + Y KE+
Sbjct: 17 TAHKAPAEISQDNPLYSLSPLDGRYKRDTAALRAYFSEYALFKYRVQVEVLYFQALCKEV 76
Query: 195 GL-----DISAAQIAELEAAVHDI----DFPAAAEHEKRVRHDVMAHVHTLGER---CPL 338
+ ++ AQ+ +L A + D + E HD+ A + L ++ C L
Sbjct: 77 PVITQLRGVTDAQLEKLRATTFENFTVDDARMIKDIEAVTNHDIKAVEYYLKDKMSACGL 136
Query: 339 AAP--IIHLGATSCYVGDNTDLIVLKNGLEL-LLPRLVAVIKQLGSFAKQYKSLPILGFT 509
A IH G TS + + + ++L++ L +P L +I L S ++ +P+L T
Sbjct: 137 EAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIAHLKSKLPEW-DVPMLART 195
Query: 510 HLQPAQLTTVGKRASLWLNDL 572
H QPA T + K +W+ L
Sbjct: 196 HGQPASPTNLAKEFMVWIERL 216
>UniRef50_P52201 Cluster: Adenylosuccinate lyase; n=5;
Mollicutes|Rep: Adenylosuccinate lyase - Spiroplasma
citri
Length = 88
Score = 40.3 bits (90), Expect = 0.036
Identities = 22/78 (28%), Positives = 41/78 (52%)
Frame = +3
Query: 93 RYASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
RY E+ +SD+ K++TW K+ + + + ++GL I I +++ + ++ P E
Sbjct: 4 RYFVTEIGKIWSDENKYNTWAKVELLVCEGWAQIGL-IPPTDIEKIKTNL-TVNLPRMLE 61
Query: 273 HEKRVRHDVMAHVHTLGE 326
E +HDV+A L E
Sbjct: 62 LEAETKHDVVAFTRMLSE 79
>UniRef50_A0P1F3 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=1; Stappia aggregata IAM 12614|Rep:
3-carboxy-cis,cis-muconate cycloisomerase - Stappia
aggregata IAM 12614
Length = 437
Score = 39.1 bits (87), Expect = 0.084
Identities = 43/131 (32%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Frame = +3
Query: 207 SAAQIAELEAAVHDIDFPAAAEHEKRVRH-DVMAHVHTLGERCPL-AAPIIHLGATSCYV 380
+A +I+E A VH I+ PA E R V A V L ++ A +H GATS V
Sbjct: 54 AAREISEKLAGVH-IE-PARLEAGTRSAGVPVPALVAELRKQLSADAGAWLHWGATSQDV 111
Query: 381 GDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLW 560
D ++ K LE+L RL +I L + ++ + G T Q A T+G R + W
Sbjct: 112 IDTAMVLQAKVALEILGARLEKLIDTLERQSARHADQLMAGRTRSQVATPITLGYRIAQW 171
Query: 561 LNDLLMDERAL 593
+ L+ E AL
Sbjct: 172 AHPLIDAENAL 182
>UniRef50_Q11F19 Cluster: Argininosuccinate lyase; n=1;
Mesorhizobium sp. BNC1|Rep: Argininosuccinate lyase -
Mesorhizobium sp. (strain BNC1)
Length = 499
Score = 38.7 bits (86), Expect = 0.11
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Frame = +3
Query: 234 AAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERC-PLAAPIIHLGATSCYVGDNTDLIVLK 410
+A+ ++ A RV + + + L ER P IHLG +S + + IVL+
Sbjct: 66 SALRHMEKEGAVATRMRVGGALHSGEYYLTERLGPKLGGTIHLGRSSADLAGVSRRIVLR 125
Query: 411 NGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERA 590
+ + +L+ V + + A + I +TH QPAQ TT +W N D +
Sbjct: 126 TAVLSMARQLIDVQLTILNTAPDHLDCIIPAYTHGQPAQPTTYAHWLMMWANVFHRDTQR 185
Query: 591 LSRAKDDL 614
L D L
Sbjct: 186 LLGGLDRL 193
>UniRef50_Q23FJ3 Cluster: Adenylosuccinate lyase family protein;
n=4; cellular organisms|Rep: Adenylosuccinate lyase
family protein - Tetrahymena thermophila SB210
Length = 488
Score = 38.7 bits (86), Expect = 0.11
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 10/135 (7%)
Frame = +3
Query: 171 LAKAEKELGLDISAAQIAELEAAVHDIDFPAAA---EHEKRVRHDVMA---HVHTLGERC 332
+ K E+ + IS + L+A D A E E HDV A ++ E+
Sbjct: 76 MVKNERGESIKISPLDLVHLDAIQQKFDIEGAKRVKEIESITNHDVKAVEYYIKEQLEKI 135
Query: 333 PLAAPI---IHLGATSCYVGDNTDLIVLKNGL-ELLLPRLVAVIKQLGSFAKQYKSLPIL 500
P+ + +H TS + + ++L + ++LL L V L S A+ ++P+L
Sbjct: 136 PVFNQVKEYVHFCCTSEDINNLAYSLMLNDAKNKILLKTLEEVQTNLISMAENNSAVPML 195
Query: 501 GFTHLQPAQLTTVGK 545
TH Q A TTVGK
Sbjct: 196 SRTHGQVASPTTVGK 210
>UniRef50_A6F014 Cluster: Fumarate lyase; n=1; Marinobacter algicola
DG893|Rep: Fumarate lyase - Marinobacter algicola DG893
Length = 447
Score = 38.3 bits (85), Expect = 0.15
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Frame = +3
Query: 99 ASKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGL-DISAAQIAELEAAVHDIDFPAAAEH 275
+ KE + SDQ + K+ LA A+ ++GL AA + + D A A
Sbjct: 18 SDKECGWYLSDQAQIKAMLKVEGQLALAQADVGLIPQEAADAINQATQLLEPDLVALAAG 77
Query: 276 EKRVRHDVMAHVHTLGERCPLA-APIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVI 452
V A V L + A +H GATS + D ++ + +++ RL+ I
Sbjct: 78 VASAGVPVPALVKALKKTLSQDFARWVHFGATSQDIVDTALILNCRELIKIYRQRLLEAI 137
Query: 453 KQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLL 575
+ A+ ++ I G T Q A + G + + W+ LL
Sbjct: 138 RLCVQLAEAHRGTLIAGRTRTQQAIPMSFGLKVANWIAPLL 178
>UniRef50_Q8U705 Cluster: Argininosuccinate lyase 2; n=3;
Alphaproteobacteria|Rep: Argininosuccinate lyase 2 -
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 504
Score = 37.1 bits (82), Expect = 0.34
Identities = 32/122 (26%), Positives = 53/122 (43%)
Frame = +3
Query: 240 VHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKNGL 419
V D F E + R+ DV +HT R + + +G LK+ +
Sbjct: 86 VEDFFFLIEKELKARIGVDVAGRLHTARSRNDIDHTLFKIG--------------LKDKI 131
Query: 420 ELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSR 599
+ L + ++K L A++ +S I+ +TH QPAQ TT G S + L+ D +
Sbjct: 132 DTLTAKARVLLKALIDAAERNQSTLIVAYTHGQPAQPTTFGHYLSAAIEVLIRDIERFTE 191
Query: 600 AK 605
A+
Sbjct: 192 AR 193
>UniRef50_Q0SH25 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=3; Rhodococcus|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Rhodococcus sp. (strain RHA1)
Length = 450
Score = 36.7 bits (81), Expect = 0.45
Identities = 27/88 (30%), Positives = 40/88 (45%)
Frame = +3
Query: 351 IHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQL 530
+H GATS + D +++ + +L L + + A+ + PI G T Q A
Sbjct: 111 VHKGATSQDILDTALMLLCRRSGAHILASLDEAVVCAEALARAQRDTPIAGRTLGQQALP 170
Query: 531 TTVGKRASLWLNDLLMDERALSRAKDDL 614
TT G A+ W+ L RAL A D L
Sbjct: 171 TTFGVLAAGWMTALHRASRALFDALDGL 198
>UniRef50_UPI00015BD1CB Cluster: UPI00015BD1CB related cluster; n=1;
unknown|Rep: UPI00015BD1CB UniRef100 entry - unknown
Length = 458
Score = 35.9 bits (79), Expect = 0.78
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +3
Query: 387 NTDL-IVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWL 563
NTDL + LK+ + + L A+ +QL AK+Y+ L + G+THLQ AQ V +
Sbjct: 114 NTDLRLYLKDHILKIFELLKALKQQLVLKAKEYEDLIMPGYTHLQRAQPVLVAHYLLSFK 173
Query: 564 NDLLMDERAL 593
L D + L
Sbjct: 174 EAFLRDSQRL 183
>UniRef50_Q311J1 Cluster: Amino acid adenylation; n=9; Bacteria|Rep:
Amino acid adenylation - Desulfovibrio desulfuricans
(strain G20)
Length = 3194
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/59 (33%), Positives = 28/59 (47%)
Frame = +3
Query: 183 EKELGLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHL 359
EKELGL +S +I E+ +F A E E + + A + T G C + P HL
Sbjct: 1787 EKELGLKLSPGRIFEMPTIAELAEFLAGVEDEAEGQKNTRAEIQTTGSTCAI-TPQPHL 1844
>UniRef50_Q92VM6 Cluster: Argininosuccinate lyase 2; n=37;
Bacteria|Rep: Argininosuccinate lyase 2 - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 488
Score = 35.5 bits (78), Expect = 1.0
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 7/133 (5%)
Frame = +3
Query: 204 ISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLG------- 362
+ ++ + + AA+ I+ A E+ + D +HT ER L A + LG
Sbjct: 54 LDESEFSAIRAALEGIEADVGAGREEPIAAD--EDLHTFLERL-LMARLGTLGGKLRAGR 110
Query: 363 ATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVG 542
+ + +NT L + + EL ++A+ + L A ++ + GFTHLQPAQ +G
Sbjct: 111 SRNDQTANNTRLYLRRMARELS-QGVIAIEEALTEQASRHTETVMPGFTHLQPAQPVVLG 169
Query: 543 KRASLWLNDLLMD 581
LL D
Sbjct: 170 HHLMAHAQSLLRD 182
>UniRef50_Q58201 Cluster: Argininosuccinate lyase; n=9;
Euryarchaeota|Rep: Argininosuccinate lyase -
Methanococcus jannaschii
Length = 484
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Frame = +3
Query: 390 TDL-IVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTT 536
TDL I L+ + ++ L+ ++K + A+++K I+G+THLQ AQ T
Sbjct: 115 TDLRIALREKVLIIAKSLIKMLKDILELAEKHKETLIVGYTHLQHAQPVT 164
>UniRef50_A0Z9A4 Cluster: SyrP protein, putative; n=3;
Proteobacteria|Rep: SyrP protein, putative - marine
gamma proteobacterium HTCC2080
Length = 332
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Frame = +3
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAK-DDL 614
+ A+ +QL SF KQ + L + +TH PAQ + WL+ L + R + K L
Sbjct: 155 MAALERQLPSFIKQCRDLGV-SYTHTMPAQADAGSGQGRSWLDTLSVTSRLAAETKLQQL 213
Query: 615 GF 620
G+
Sbjct: 214 GY 215
>UniRef50_A0CTV0 Cluster: Chromosome undetermined scaffold_27, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_27,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 881
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/51 (33%), Positives = 26/51 (50%)
Frame = +3
Query: 15 DKMTTIDAPVELQNTEYCNYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWI 167
+K+T I+ VE N +Y + + +KE + DQ K S W +LWI
Sbjct: 316 EKLTKIENEVE--NQQYAHQTQVAFVTFQTKEQLQSVLDQTKLSHWEELWI 364
>UniRef50_Q9RV01 Cluster: Putative uncharacterized protein; n=1;
Deinococcus radiodurans|Rep: Putative uncharacterized
protein - Deinococcus radiodurans
Length = 319
Score = 33.9 bits (74), Expect = 3.1
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 4/43 (9%)
Frame = -3
Query: 366 WLPGV*WARRGDTSRRACGHAPSRR----DEPASHVQQPLGSR 250
W PG A R T+R +C H+PSRR P S +P +R
Sbjct: 252 WTPGAPAAPRATTTRNSCSHSPSRRVWRLTTPGSTPSRPASAR 294
>UniRef50_A6S8F2 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 363
Score = 33.9 bits (74), Expect = 3.1
Identities = 44/140 (31%), Positives = 64/140 (45%), Gaps = 3/140 (2%)
Frame = +3
Query: 150 WRKLWIYLAKAEKELGLDISAAQIAEL--EAAVHDIDFPAAA-EHEKRVRHDVMAHVHTL 320
+ LW + K G I + IA+L E A ++ +H R D++ V+T
Sbjct: 10 YEPLWEDVHARAKANGFKIRSIWIADLAHEGASSVLNEQLLGNDHHAR---DLLHMVNTY 66
Query: 321 GERCPLAAPIIHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPIL 500
PL PII +G + +G N +L N L L+ PRL+ + L +QY S P
Sbjct: 67 RSEMPL--PIIGIGHS---LGAN----MLTN-LSLMHPRLLTTLIMLDPVIQQYASTP-- 114
Query: 501 GFTHLQPAQLTTVGKRASLW 560
F + PAQL+T R LW
Sbjct: 115 -FGTISPAQLSTF--RRDLW 131
>UniRef50_Q3IVC5 Cluster: Arginino succinate lyase; n=4;
Rhodobacteraceae|Rep: Arginino succinate lyase -
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
NCIB 8253 / DSM158)
Length = 499
Score = 33.5 bits (73), Expect = 4.2
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 258 PAAAEHEKRVRHDVMAHVHTLGERCPLA-APIIHLGATSCYVGDNTDLIVLKNGLELLLP 434
PAA + + + A + LG+ A A +H+G + +G D + + LL
Sbjct: 74 PAAIDLDPQFEDSYFAFENRLGQVAGKAVAGWLHVGRSRNDIGSTLDRMAARETCLALLA 133
Query: 435 RLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVG 542
+ + + A ++ + G+THLQPAQ T G
Sbjct: 134 AMEEARRACLAAAGRHVLTVMPGYTHLQPAQPITFG 169
>UniRef50_Q11GN0 Cluster: 3-carboxy-cis,cis-muconate cycloisomerase;
n=14; Rhizobiales|Rep: 3-carboxy-cis,cis-muconate
cycloisomerase - Mesorhizobium sp. (strain BNC1)
Length = 354
Score = 33.5 bits (73), Expect = 4.2
Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 4/143 (2%)
Frame = +3
Query: 174 AKAEKELGLDISAAQIAELEAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGE-RCPLAAPI 350
A AE E D+ + + AE AA P + + D + L + R L+A
Sbjct: 39 ALAEAEAEEDVISQEAAEAIAAAVQQFKPDVGALSRGIARDGVVIPALLDQLRQKLSAEH 98
Query: 351 ---IHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQP 521
+H GATS D + L LL RL VI+ L + ++ + ++ T +Q
Sbjct: 99 RTRLHFGATSQDAIDTGLAMRLIEATALLATRLNEVIESLDALERRDGGVEVMAHTRMQA 158
Query: 522 AQLTTVGKRASLWLNDLLMDERA 590
A T ++ + W + LM RA
Sbjct: 159 AIPVTAARKIASW-REPLMRHRA 180
>UniRef50_Q4MYR8 Cluster: Adenylosuccinate lyase, putative; n=1;
Theileria parva|Rep: Adenylosuccinate lyase, putative -
Theileria parva
Length = 469
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Frame = +3
Query: 351 IHLGATSCYVGDNTDLIVLKNGLELLL-PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQ 527
+H+ TS + + + +++ + ++ P ++ +I L A + +P+L TH QPA
Sbjct: 116 VHVFCTSEDINSPSYSMGIRDCMNFVMKPLMLEIISSLCKLALENAKMPMLSRTHGQPAI 175
Query: 528 LTTVGKRASLWL 563
TT GK S ++
Sbjct: 176 PTTFGKEVSTFV 187
>UniRef50_Q8ZU95 Cluster: Argininosuccinate lyase; n=4;
Pyrobaculum|Rep: Argininosuccinate lyase - Pyrobaculum
aerophilum
Length = 429
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/52 (36%), Positives = 28/52 (53%)
Frame = +3
Query: 459 LGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRAKDDL 614
L A +Y P+ FTH QPAQ+ T G L +++LL + + R +DL
Sbjct: 133 LAKRALEYADCPMPSFTHFQPAQVITFG-HYLLAIDELLAEFLHILRGVEDL 183
>UniRef50_Q8PUM6 Cluster: Argininosuccinate lyase; n=7; Archaea|Rep:
Argininosuccinate lyase - Methanosarcina mazei
(Methanosarcina frisia)
Length = 491
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/47 (40%), Positives = 28/47 (59%)
Frame = +3
Query: 399 IVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTV 539
+ L+ L LL + A+ K L S A+++ + GFTHLQ AQ TT+
Sbjct: 118 LTLREELLGLLEEIFALRKTLVSLAEKHSETLMPGFTHLQHAQPTTL 164
>UniRef50_Q8TXN9 Cluster: Argininosuccinate lyase; n=1; Methanopyrus
kandleri|Rep: Argininosuccinate lyase - Methanopyrus
kandleri
Length = 508
Score = 33.5 bits (73), Expect = 4.2
Identities = 18/54 (33%), Positives = 29/54 (53%)
Frame = +3
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSR 599
LV + + L A+++ +PI G+THL+ AQ T+G S + + R L R
Sbjct: 133 LVGLGRALLDLAREHAEVPIAGYTHLKRAQPCTIGFWMSTYAAAVARSARGLLR 186
>UniRef50_Q8UGS2 Cluster: Putative uncharacterized protein Atu0963;
n=1; Agrobacterium tumefaciens str. C58|Rep: Putative
uncharacterized protein Atu0963 - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 332
Score = 33.1 bits (72), Expect = 5.5
Identities = 17/37 (45%), Positives = 23/37 (62%)
Frame = -3
Query: 288 EPASHVQQPLGSRCRVQQLLVRLSERRLYPIRAPFQL 178
EPA H+ QPL +R R Q +RR P+RAPF++
Sbjct: 164 EPAQHIVQPLAARRRCLQ---GGGQRRPEPLRAPFEI 197
>UniRef50_Q8DH74 Cluster: Tlr2085 protein; n=1; Synechococcus
elongatus|Rep: Tlr2085 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 896
Score = 33.1 bits (72), Expect = 5.5
Identities = 17/63 (26%), Positives = 30/63 (47%)
Frame = +3
Query: 234 AAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLGATSCYVGDNTDLIVLKN 413
A +DFP A++E + D+M + L +R A + + + GD ++I L N
Sbjct: 18 ATATGVDFPGFAQNEAQQLRDIMQRLDALQQRYSAAVSELEAIRKTSFGGDTHNVIALTN 77
Query: 414 GLE 422
+E
Sbjct: 78 QIE 80
>UniRef50_Q2LYB8 Cluster: DNA polymerase III subunit gamma/tau; n=1;
Syntrophus aciditrophicus SB|Rep: DNA polymerase III
subunit gamma/tau - Syntrophus aciditrophicus (strain
SB)
Length = 588
Score = 33.1 bits (72), Expect = 5.5
Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 12/94 (12%)
Frame = -1
Query: 521 RLKMGEA---EDGQRLVLFREASKLFDDGDEPWQKQLESVLKD--YQIGVVSDVARGGSQ 357
+++ GE E+G + FR+ S F+D +EP QK S L ++ V D+ ++
Sbjct: 465 KIEQGECLGCENGHLRIGFRKGSVFFEDLNEPEQKSRLSELAGSFFKTAVTVDIEPVETE 524
Query: 356 VYDGRGEGTPLAERV-------DMRHHVVTNPLL 276
DGRG G L+E + ++R + +PLL
Sbjct: 525 -SDGRGSGGRLSEAMARKNQAEELRREALNHPLL 557
>UniRef50_A6DT96 Cluster: Argininosuccinate lyase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Argininosuccinate lyase -
Lentisphaera araneosa HTCC2155
Length = 431
Score = 33.1 bits (72), Expect = 5.5
Identities = 16/55 (29%), Positives = 32/55 (58%)
Frame = +3
Query: 438 LVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLWLNDLLMDERALSRA 602
L + I++L + A +Y++ P+ G+TH Q A +++G AS + L+ + + A
Sbjct: 134 LKSFIEELLNLASKYETTPMPGYTHTQRAMPSSIGLWASSFAEILINQKETIDAA 188
>UniRef50_P39461 Cluster: Fumarate hydratase class II; n=10;
Thermoprotei|Rep: Fumarate hydratase class II -
Sulfolobus solfataricus
Length = 438
Score = 33.1 bits (72), Expect = 5.5
Identities = 17/45 (37%), Positives = 25/45 (55%)
Frame = +3
Query: 426 LLPRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQLTTVGKRASLW 560
LLP L +I L A++YK + G THL+ A T+G+ S +
Sbjct: 132 LLPALQQIISSLNKKAEEYKDVIKAGRTHLRDALPVTLGQELSAY 176
>UniRef50_A3PGB8 Cluster: Histidine kinase precursor; n=3;
Rhodobacter sphaeroides|Rep: Histidine kinase precursor
- Rhodobacter sphaeroides (strain ATCC 17029 / ATH
2.4.9)
Length = 597
Score = 32.7 bits (71), Expect = 7.3
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 15/103 (14%)
Frame = +3
Query: 231 EAAVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIH------------LGATSC 374
EA H+I+ AEHE R H+ + H L +++ I+H L A
Sbjct: 336 EALAHEIEERRRAEHELRETHEHLVHAAKLAVLGRMSSTIVHEVSQPLSALEATLAAAEL 395
Query: 375 YVG-DNTD--LIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLP 494
++G +N + L +++G +LLL R+ ++K L SF + + P
Sbjct: 396 HLGRENPERALRSVRSGRDLLL-RMQKMVKALKSFGSRQRLDP 437
>UniRef50_A2SE36 Cluster: Putative uncharacterized protein; n=1;
Methylibium petroleiphilum PM1|Rep: Putative
uncharacterized protein - Methylibium petroleiphilum
(strain PM1)
Length = 99
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/42 (35%), Positives = 25/42 (59%)
Frame = +3
Query: 237 AVHDIDFPAAAEHEKRVRHDVMAHVHTLGERCPLAAPIIHLG 362
A+H ID PA+ E +R+R AH+ + +R +A P++ G
Sbjct: 4 ALHMIDKPASLELRQRLRPAHRAHLDLIADRLAIAGPLLDEG 45
>UniRef50_Q01IZ6 Cluster: OSIGBa0111L12.6 protein; n=1; Oryza
sativa|Rep: OSIGBa0111L12.6 protein - Oryza sativa
(Rice)
Length = 264
Score = 32.7 bits (71), Expect = 7.3
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Frame = +2
Query: 284 GSSRRDGAC---PHARREVS-PRRAHHTPGSHLVLRRRQHRFDSP 406
G+ RR+G P RR+V PRR HH P + RR HR D P
Sbjct: 185 GAHRREGGAELDPRRRRKVPVPRRRHHVPPRRRRVHRR-HRQDHP 228
>UniRef50_A0D0R1 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 217
Score = 32.7 bits (71), Expect = 7.3
Identities = 17/54 (31%), Positives = 27/54 (50%)
Frame = +3
Query: 9 KFDKMTTIDAPVELQNTEYCNYRSPLSTRYASKEMQYNFSDQKKFSTWRKLWIY 170
K D+ T PV +N+E R L A+ + ++ + Q+ S+W KLW Y
Sbjct: 23 KGDQYETPTLPVYQKNSEISQIRIKLGVTGATYVVPHDENQQRCMSSWNKLWGY 76
>UniRef50_Q9WYD8 Cluster: Oligopeptide ABC transporter, permease
protein; n=5; Thermotogaceae|Rep: Oligopeptide ABC
transporter, permease protein - Thermotoga maritima
Length = 289
Score = 32.3 bits (70), Expect = 9.6
Identities = 18/51 (35%), Positives = 27/51 (52%)
Frame = +3
Query: 351 IHLGATSCYVGDNTDLIVLKNGLELLLPRLVAVIKQLGSFAKQYKSLPILG 503
I +G S Y+G TD I++ ++ + ++ L S K Y SLPILG
Sbjct: 95 ITIGMLSGYLGGTTDRILMALTDTFMVMPVFPLLLLLSSLIKNYLSLPILG 145
>UniRef50_A2P810 Cluster: RTX protein; n=4; Vibrio cholerae|Rep: RTX
protein - Vibrio cholerae 1587
Length = 2093
Score = 32.3 bits (70), Expect = 9.6
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = -1
Query: 416 SVLKDYQIGVVSDVARGGSQVYDGRGE 336
+++K++Q GVV DV GG VY G+G+
Sbjct: 1836 ALVKEHQDGVVVDVGAGGDNVYLGKGD 1862
>UniRef50_Q4UB18 Cluster: Adenylosuccinate lyase, putative; n=1;
Theileria annulata|Rep: Adenylosuccinate lyase, putative
- Theileria annulata
Length = 407
Score = 32.3 bits (70), Expect = 9.6
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Frame = +3
Query: 351 IHLGATSCYVGDNTDLIVLKNGLELLL-PRLVAVIKQLGSFAKQYKSLPILGFTHLQPAQ 527
+H+ TS + + + +++ + ++ P ++ +I L A + +P+L TH QPA
Sbjct: 105 VHIFCTSEDINSPSYSMGIRDCMNYVVKPLMLQIISTLCKLALENARMPMLSRTHGQPAI 164
Query: 528 LTTVGKRASLWL 563
TT GK S ++
Sbjct: 165 PTTFGKEVSTFV 176
>UniRef50_A7TJF2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1274
Score = 32.3 bits (70), Expect = 9.6
Identities = 16/57 (28%), Positives = 27/57 (47%)
Frame = +3
Query: 102 SKEMQYNFSDQKKFSTWRKLWIYLAKAEKELGLDISAAQIAELEAAVHDIDFPAAAE 272
SKE Q S ++ TWRK W Y+ + E L + ++ + D P+A++
Sbjct: 578 SKEAQA--STERYKHTWRKTWYYIVSMDVEQSLSLGTPRLLRTIRDISDTKLPSASK 632
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 620,252,083
Number of Sequences: 1657284
Number of extensions: 12698312
Number of successful extensions: 45221
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 43226
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45178
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45221970467
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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