Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-1232
(444 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 205 6e-53
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 200 2e-51
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 200 2e-51
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 200 2e-51
Z25428-1|CAA80915.1| 111|Homo sapiens protein-serine/threonine ... 146 3e-35
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 138 8e-33
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 138 8e-33
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 138 8e-33
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 138 8e-33
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 138 8e-33
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 138 8e-33
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 138 8e-33
AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein. 138 8e-33
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 138 8e-33
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 138 8e-33
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 138 8e-33
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 138 8e-33
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 135 6e-32
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 135 6e-32
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 135 6e-32
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 135 6e-32
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 132 4e-31
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 132 4e-31
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 131 1e-30
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 130 2e-30
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 130 2e-30
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 130 2e-30
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 130 2e-30
AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4 ... 118 9e-27
AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4 ... 118 9e-27
AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4b... 116 4e-26
AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase 4a... 116 4e-26
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 113 3e-25
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 113 3e-25
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 113 3e-25
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 113 3e-25
DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated prote... 107 2e-23
BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated prote... 107 2e-23
BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated prote... 107 2e-23
AL121964-4|CAI19611.1| 579|Homo sapiens mitogen-activated prote... 107 2e-23
AL121964-3|CAI19612.1| 606|Homo sapiens mitogen-activated prote... 107 2e-23
AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated prote... 107 2e-23
AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated prote... 107 2e-23
AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated prote... 107 2e-23
AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated prote... 107 2e-23
AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated prote... 107 2e-23
AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated prote... 107 2e-23
AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kina... 107 2e-23
AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kina... 107 2e-23
AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kina... 107 2e-23
AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kina... 107 2e-23
BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated prote... 106 4e-23
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 105 5e-23
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 105 5e-23
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 105 5e-23
BC111726-1|AAI11727.1| 656|Homo sapiens MAP3K13 protein protein. 105 5e-23
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 105 5e-23
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 105 5e-23
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 105 5e-23
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 103 3e-22
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 103 3e-22
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 103 3e-22
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 103 4e-22
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 103 4e-22
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 103 4e-22
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 103 4e-22
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 103 4e-22
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 103 4e-22
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 103 4e-22
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 101 1e-21
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 101 1e-21
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 101 1e-21
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 101 1e-21
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 101 1e-21
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 101 1e-21
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 101 1e-21
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 101 1e-21
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 101 1e-21
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 101 1e-21
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 101 1e-21
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 101 1e-21
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 99 6e-21
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 99 6e-21
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 99 6e-21
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 99 6e-21
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 99 6e-21
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 99 6e-21
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 99 8e-21
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 99 8e-21
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 98 1e-20
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 98 1e-20
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 98 1e-20
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 98 1e-20
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 98 1e-20
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 98 1e-20
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 98 1e-20
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 98 1e-20
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 98 1e-20
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 98 1e-20
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 98 1e-20
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 98 1e-20
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 98 1e-20
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 97 2e-20
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 97 2e-20
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 97 2e-20
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 97 2e-20
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 97 2e-20
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 97 2e-20
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 97 2e-20
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 97 3e-20
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 97 3e-20
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 97 3e-20
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 97 3e-20
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 96 4e-20
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 96 4e-20
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 96 4e-20
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 96 4e-20
AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 96 4e-20
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 96 4e-20
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 96 4e-20
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 96 6e-20
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 96 6e-20
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 96 6e-20
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 96 6e-20
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 95 7e-20
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 95 7e-20
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 95 7e-20
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 95 7e-20
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 95 7e-20
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 95 1e-19
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 95 1e-19
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 94 2e-19
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 94 2e-19
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 94 2e-19
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 94 2e-19
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 94 2e-19
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 94 2e-19
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 94 2e-19
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 94 2e-19
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 94 2e-19
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 94 2e-19
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 94 2e-19
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 94 2e-19
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 94 2e-19
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 94 2e-19
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 94 2e-19
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 94 2e-19
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 94 2e-19
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 94 2e-19
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 94 2e-19
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 94 2e-19
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 93 3e-19
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 93 3e-19
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 93 3e-19
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 93 3e-19
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 93 3e-19
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 93 3e-19
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 93 3e-19
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 93 3e-19
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 93 3e-19
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 93 3e-19
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 93 3e-19
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 93 3e-19
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 93 4e-19
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 93 4e-19
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 93 4e-19
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 93 4e-19
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 93 4e-19
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 93 4e-19
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 93 4e-19
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 93 4e-19
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 93 4e-19
AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyros... 93 4e-19
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 93 4e-19
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 93 5e-19
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 93 5e-19
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 93 5e-19
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 93 5e-19
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 93 5e-19
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 92 7e-19
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 92 7e-19
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 92 7e-19
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 92 7e-19
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 92 7e-19
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 92 7e-19
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 92 7e-19
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 92 7e-19
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 92 7e-19
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 92 7e-19
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 92 7e-19
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 92 7e-19
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 92 7e-19
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 92 7e-19
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 92 7e-19
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 92 7e-19
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 92 7e-19
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 92 7e-19
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 92 7e-19
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 92 7e-19
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 92 7e-19
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 92 7e-19
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 92 7e-19
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 92 7e-19
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 92 7e-19
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 92 7e-19
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 92 7e-19
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 92 7e-19
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 92 7e-19
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 92 9e-19
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 92 9e-19
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 92 9e-19
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 92 9e-19
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 92 9e-19
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 92 9e-19
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 92 9e-19
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 92 9e-19
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 92 9e-19
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 92 9e-19
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 92 9e-19
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 92 9e-19
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 92 9e-19
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 92 9e-19
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 92 9e-19
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 92 9e-19
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 92 9e-19
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 92 9e-19
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 92 9e-19
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 92 9e-19
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 92 9e-19
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 92 9e-19
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 92 9e-19
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 92 9e-19
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 92 9e-19
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, t... 92 9e-19
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 92 9e-19
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 91 1e-18
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 91 1e-18
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 91 1e-18
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 91 2e-18
BC008655-1|AAH08655.1| 253|Homo sapiens EPHA2 protein protein. 91 2e-18
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 91 2e-18
AL121991-2|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 91 2e-18
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 90 3e-18
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 90 3e-18
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 90 3e-18
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 90 3e-18
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 90 4e-18
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 90 4e-18
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 90 4e-18
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 90 4e-18
U22512-1|AAC50713.1| 714|Homo sapiens CHUK protein. 90 4e-18
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 90 4e-18
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 90 4e-18
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 90 4e-18
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 90 4e-18
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 90 4e-18
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 90 4e-18
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 90 4e-18
AY652653-1|AAT49098.1| 745|Homo sapiens conserved helix-loop-he... 90 4e-18
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 90 4e-18
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 90 4e-18
AL138921-4|CAH72401.1| 745|Homo sapiens conserved helix-loop-he... 90 4e-18
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 90 4e-18
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 90 4e-18
AF080157-1|AAD08996.1| 745|Homo sapiens IkB kinase-a protein. 90 4e-18
AF012890-1|AAC51662.1| 745|Homo sapiens IKK-a kinase protein. 90 4e-18
AF009225-1|AAC51671.1| 745|Homo sapiens IkB kinase alpha subuni... 90 4e-18
AB209028-1|BAD92265.1| 726|Homo sapiens conserved helix-loop-he... 90 4e-18
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 89 5e-18
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 89 5e-18
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 89 5e-18
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 89 5e-18
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 89 5e-18
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 89 5e-18
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 89 5e-18
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 89 5e-18
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 89 5e-18
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 89 5e-18
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 89 5e-18
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 89 6e-18
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 89 6e-18
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 89 6e-18
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 89 6e-18
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 89 6e-18
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 89 6e-18
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 89 6e-18
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 89 6e-18
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 89 6e-18
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 89 6e-18
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 89 6e-18
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 89 6e-18
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 89 6e-18
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 89 6e-18
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 89 6e-18
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 89 6e-18
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 89 6e-18
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 89 8e-18
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 89 8e-18
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 89 8e-18
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 89 8e-18
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 89 8e-18
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 89 8e-18
BC092514-1|AAH92514.1| 745|Homo sapiens conserved helix-loop-he... 89 8e-18
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 89 8e-18
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 89 8e-18
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 89 8e-18
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 89 8e-18
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 89 8e-18
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 89 8e-18
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 88 1e-17
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 88 1e-17
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 88 1e-17
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 88 1e-17
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 88 1e-17
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 88 1e-17
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 88 1e-17
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 88 1e-17
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 88 1e-17
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 88 1e-17
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 88 1e-17
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 88 1e-17
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 87 2e-17
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 87 2e-17
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 87 2e-17
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 87 2e-17
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 87 2e-17
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 87 2e-17
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 87 2e-17
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 87 2e-17
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 87 2e-17
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 87 2e-17
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 87 2e-17
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 87 2e-17
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 87 2e-17
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 87 2e-17
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 87 2e-17
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 87 2e-17
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 87 2e-17
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 87 2e-17
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 87 2e-17
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 87 2e-17
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 87 2e-17
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 87 2e-17
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 87 3e-17
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 87 3e-17
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 87 3e-17
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 87 3e-17
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 87 3e-17
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 87 3e-17
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 87 3e-17
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 87 3e-17
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 87 3e-17
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 87 3e-17
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 87 3e-17
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 87 3e-17
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 87 3e-17
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 87 3e-17
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 87 3e-17
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 87 3e-17
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 87 3e-17
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 87 3e-17
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 87 3e-17
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 87 3e-17
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 87 3e-17
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 87 3e-17
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 87 3e-17
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 87 3e-17
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 87 3e-17
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 87 3e-17
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 87 3e-17
AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit... 87 3e-17
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 87 3e-17
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 87 3e-17
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 87 3e-17
AB209090-1|BAD92327.1| 483|Homo sapiens inhibitor of kappa ligh... 87 3e-17
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 87 3e-17
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 86 5e-17
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 86 5e-17
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 86 5e-17
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 86 5e-17
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 86 5e-17
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 86 5e-17
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 86 5e-17
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 86 5e-17
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 86 6e-17
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 86 6e-17
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 86 6e-17
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 86 6e-17
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 86 6e-17
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 86 6e-17
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 86 6e-17
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 86 6e-17
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 86 6e-17
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 86 6e-17
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 86 6e-17
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 86 6e-17
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 86 6e-17
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 86 6e-17
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 86 6e-17
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 86 6e-17
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 86 6e-17
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 85 8e-17
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 85 8e-17
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 85 8e-17
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 85 8e-17
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 85 8e-17
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 85 8e-17
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 85 8e-17
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 85 8e-17
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 85 1e-16
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 85 1e-16
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 85 1e-16
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 85 1e-16
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 85 1e-16
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 85 1e-16
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 85 1e-16
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 85 1e-16
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 85 1e-16
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 85 1e-16
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 85 1e-16
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 85 1e-16
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 85 1e-16
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 85 1e-16
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 85 1e-16
AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6 ki... 85 1e-16
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 85 1e-16
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 85 1e-16
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 85 1e-16
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 85 1e-16
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 85 1e-16
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 85 1e-16
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 85 1e-16
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 85 1e-16
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 85 1e-16
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 85 1e-16
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 85 1e-16
J00119-1|AAA52029.1| 346|Homo sapiens MOS protein. 85 1e-16
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 85 1e-16
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 85 1e-16
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 85 1e-16
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 85 1e-16
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 85 1e-16
BC106738-1|AAI06739.1| 346|Homo sapiens v-mos Moloney murine sa... 85 1e-16
BC106737-1|AAI06738.1| 346|Homo sapiens v-mos Moloney murine sa... 85 1e-16
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 85 1e-16
BC069590-1|AAH69590.1| 346|Homo sapiens MOS protein protein. 85 1e-16
BC069569-1|AAH69569.1| 346|Homo sapiens v-mos Moloney murine sa... 85 1e-16
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 85 1e-16
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 85 1e-16
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 85 1e-16
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 85 1e-16
AF153364-1|AAF61477.1| 149|Homo sapiens Bruton's tyrosine kinas... 85 1e-16
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 85 1e-16
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 85 1e-16
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 85 1e-16
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 84 2e-16
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 84 2e-16
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 84 2e-16
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 84 2e-16
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 84 2e-16
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 84 2e-16
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 84 2e-16
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 84 2e-16
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 84 2e-16
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 84 2e-16
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 84 2e-16
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 84 2e-16
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 84 2e-16
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 84 2e-16
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 84 2e-16
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 84 2e-16
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 84 2e-16
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 84 2e-16
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 84 2e-16
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 84 2e-16
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 84 2e-16
AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinas... 84 2e-16
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 84 2e-16
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 84 2e-16
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 84 2e-16
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 84 2e-16
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 84 2e-16
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 84 2e-16
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 84 2e-16
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 84 2e-16
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 84 2e-16
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 84 2e-16
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 84 2e-16
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 84 2e-16
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 84 2e-16
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 84 2e-16
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 205 bits (500), Expect = 6e-53
Identities = 91/144 (63%), Positives = 112/144 (77%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
YCIIME+C +G LY+ L +G TPR ++ W+ IA GM YLH KIIHRDLKSPNVLV
Sbjct: 229 YCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVT 288
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
K+SDFGTS+E ++S MSF GTVAWMAPEVIR+EP SE+VD+WSFGVVLWELLT
Sbjct: 289 HTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 348
Query: 370 QEIPYKTLETHAILWGVGTETILL 441
EIPYK +++ AI+WGVG+ ++ L
Sbjct: 349 GEIPYKDVDSSAIIWGVGSNSLHL 372
>U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein
kinase protein.
Length = 859
Score = 200 bits (487), Expect = 2e-51
Identities = 89/144 (61%), Positives = 112/144 (77%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
YCI+MEFC G LY+ L +G TP ++ W+ IA GM YLH KIIHRDLKSPN+L+
Sbjct: 186 YCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT 245
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
+ V K+SDFGTS+E ++S MSF GTVAWMAPEVIR+EP SE+VD+WSFGVVLWELLT
Sbjct: 246 YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 305
Query: 370 QEIPYKTLETHAILWGVGTETILL 441
EIPYK +++ AI+WGVG+ ++ L
Sbjct: 306 GEIPYKDVDSSAIIWGVGSNSLHL 329
>BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein.
Length = 567
Score = 200 bits (487), Expect = 2e-51
Identities = 89/144 (61%), Positives = 112/144 (77%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
YCI+MEFC G LY+ L +G TP ++ W+ IA GM YLH KIIHRDLKSPN+L+
Sbjct: 219 YCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT 278
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
+ V K+SDFGTS+E ++S MSF GTVAWMAPEVIR+EP SE+VD+WSFGVVLWELLT
Sbjct: 279 YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 338
Query: 370 QEIPYKTLETHAILWGVGTETILL 441
EIPYK +++ AI+WGVG+ ++ L
Sbjct: 339 GEIPYKDVDSSAIIWGVGSNSLHL 362
>AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase
protein.
Length = 859
Score = 200 bits (487), Expect = 2e-51
Identities = 89/144 (61%), Positives = 112/144 (77%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
YCI+MEFC G LY+ L +G TP ++ W+ IA GM YLH KIIHRDLKSPN+L+
Sbjct: 186 YCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT 245
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
+ V K+SDFGTS+E ++S MSF GTVAWMAPEVIR+EP SE+VD+WSFGVVLWELLT
Sbjct: 246 YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 305
Query: 370 QEIPYKTLETHAILWGVGTETILL 441
EIPYK +++ AI+WGVG+ ++ L
Sbjct: 306 GEIPYKDVDSSAIIWGVGSNSLHL 329
>Z25428-1|CAA80915.1| 111|Homo sapiens protein-serine/threonine
kinase protein.
Length = 111
Score = 146 bits (354), Expect = 3e-35
Identities = 65/108 (60%), Positives = 80/108 (74%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+ ME+C +G LY+ L +G TPR ++ W+ IA GM YLH KIIHRDLKSPNVLV
Sbjct: 2 LYMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHT 61
Query: 196 LVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWS 339
K+SDFGTS+E ++S MSF GTVAWMAPEVIR+EP SE+VD+WS
Sbjct: 62 DAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWS 109
>BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and
leucine zipper containing kinase AZK protein.
Length = 455
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage
kinase-related kinase MRK-beta protein.
Length = 455
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage
kinase-related kinase MRK-alpha protein.
Length = 800
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppressor
gene-4 protein protein.
Length = 312
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase
protein.
Length = 455
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and
leucine zipper containing kinase AZK protein.
Length = 800
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZAK
protein.
Length = 800
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein.
Length = 400
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 24 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 83
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 84 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 142
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 143 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 173
>AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage
kinase protein variant protein.
Length = 845
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 122 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 181
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 182 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 240
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 241 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 271
>AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein.
Length = 455
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein.
Length = 800
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage
kinase protein protein.
Length = 800
Score = 138 bits (334), Expect = 8e-33
Identities = 72/151 (47%), Positives = 96/151 (63%), Gaps = 5/151 (3%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGAS--FTPRQIIRWAKDIAQGMVYLHNR---KIIHRDLKS 171
NY I+ E+ G LYD+++S S I+ WA D+A+GM YLH K+IHRDLKS
Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136
Query: 172 PNVLVADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
NV++A + V K+ DFG SR + N + MS GT WMAPEVI+ P SE D +S+GVV
Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVV 195
Query: 352 LWELLTQEIPYKTLETHAILWGVGTETILLT 444
LWE+LT+E+P+K LE + W V + LT
Sbjct: 196 LWEMLTREVPFKGLEGLQVAWLVVEKNERLT 226
>BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein.
Length = 1104
Score = 135 bits (327), Expect = 6e-32
Identities = 71/156 (45%), Positives = 97/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKI---IHRDLKSPN 177
N C++MEF + GPL L SG P ++ WA IA+GM YLH+ I IHRDLKS N
Sbjct: 215 NLCLVMEFARGGPLNRVL-SGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 273
Query: 178 VLVAD--------NLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ N + K++DFG +REW + + MS GT AWMAPEVIR S+ DV
Sbjct: 274 ILILQKVENGDLSNKILKITDFGLAREW-HRTTKMSAAGTYAWMAPEVIRASMFSKGSDV 332
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WS+GV+LWELLT E+P++ ++ A+ +GV + L
Sbjct: 333 WSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLAL 368
>BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein.
Length = 1103
Score = 135 bits (327), Expect = 6e-32
Identities = 71/156 (45%), Positives = 97/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKI---IHRDLKSPN 177
N C++MEF + GPL L SG P ++ WA IA+GM YLH+ I IHRDLKS N
Sbjct: 214 NLCLVMEFARGGPLNRVL-SGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 272
Query: 178 VLVAD--------NLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ N + K++DFG +REW + + MS GT AWMAPEVIR S+ DV
Sbjct: 273 ILILQKVENGDLSNKILKITDFGLAREW-HRTTKMSAAGTYAWMAPEVIRASMFSKGSDV 331
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WS+GV+LWELLT E+P++ ++ A+ +GV + L
Sbjct: 332 WSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLAL 367
>AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein
kinase 1 protein.
Length = 1104
Score = 135 bits (327), Expect = 6e-32
Identities = 71/156 (45%), Positives = 97/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKI---IHRDLKSPN 177
N C++MEF + GPL L SG P ++ WA IA+GM YLH+ I IHRDLKS N
Sbjct: 215 NLCLVMEFARGGPLNRVL-SGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 273
Query: 178 VLVAD--------NLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ N + K++DFG +REW + + MS GT AWMAPEVIR S+ DV
Sbjct: 274 ILILQKVENGDLSNKILKITDFGLAREW-HRTTKMSAAGTYAWMAPEVIRASMFSKGSDV 332
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WS+GV+LWELLT E+P++ ++ A+ +GV + L
Sbjct: 333 WSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLAL 368
>AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase MLK1
protein.
Length = 1066
Score = 135 bits (327), Expect = 6e-32
Identities = 71/156 (45%), Positives = 97/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKI---IHRDLKSPN 177
N C++MEF + GPL L SG P ++ WA IA+GM YLH+ I IHRDLKS N
Sbjct: 163 NLCLVMEFARGGPLNRVL-SGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 221
Query: 178 VLVAD--------NLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ N + K++DFG +REW + + MS GT AWMAPEVIR S+ DV
Sbjct: 222 ILILQKVENGDLSNKILKITDFGLAREW-HRTTKMSAAGTYAWMAPEVIRASMFSKGSDV 280
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WS+GV+LWELLT E+P++ ++ A+ +GV + L
Sbjct: 281 WSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLAL 316
>Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase with
SH3 domain, leucine zipper domain and proline rich
protein.
Length = 953
Score = 132 bits (320), Expect = 4e-31
Identities = 71/154 (46%), Positives = 98/154 (63%), Gaps = 11/154 (7%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPNVL 183
C++ME+ + G L L +G P ++ WA +A+GM YLHN IIHRDLKS N+L
Sbjct: 171 CLVMEYARGGALSRVL-AGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINIL 229
Query: 184 VAD-----NL---VAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWS 339
+ + NL V K++DFG +REW +++ MS GT AWMAPEVIR S+ DVWS
Sbjct: 230 ILEAIENHNLADTVLKITDFGLAREW-HKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWS 288
Query: 340 FGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
FGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 289 FGVLLWELLTGEVPYREIDALAVAYGVAMNKLTL 322
>X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2
protein.
Length = 954
Score = 132 bits (320), Expect = 4e-31
Identities = 71/154 (46%), Positives = 98/154 (63%), Gaps = 11/154 (7%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPNVL 183
C++ME+ + G L L +G P ++ WA +A+GM YLHN IIHRDLKS N+L
Sbjct: 171 CLVMEYARGGALSRVL-AGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINIL 229
Query: 184 VAD-----NL---VAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWS 339
+ + NL V K++DFG +REW +++ MS GT AWMAPEVIR S+ DVWS
Sbjct: 230 ILEAIENHNLADTVLKITDFGLAREW-HKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWS 288
Query: 340 FGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
FGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 289 FGVLLWELLTGEVPYREIDALAVAYGVAMNKLTL 322
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 131 bits (316), Expect = 1e-30
Identities = 68/156 (43%), Positives = 97/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPN 177
N C++ME+ GPL L +G P ++ WA IA+GM YLH +IHRDLKS N
Sbjct: 188 NLCLVMEYAAGGPLSRAL-AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNN 246
Query: 178 VLVADNLVA--------KVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ ++ + K++DFG +REW +++ MS GT AWMAPEVI+ S+ DV
Sbjct: 247 ILLLQHIESDDMEHKTLKITDFGLAREW-HKTTQMSAAGTYAWMAPEVIKASTFSKGSDV 305
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WSFGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 306 WSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTL 341
>U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein
kinase protein.
Length = 847
Score = 130 bits (315), Expect = 2e-30
Identities = 69/156 (44%), Positives = 98/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPN 177
N C++ME+ GPL L +G P ++ WA IA+GM YLH +IHRDLKS N
Sbjct: 188 NLCLVMEYAAGGPLSRAL-AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNN 246
Query: 178 VLV-----ADNL---VAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ +D++ K++DFG +REW +++ MS GT AWMAPEVI+ S+ DV
Sbjct: 247 ILLLQPIESDDMEHKTLKITDFGLAREW-HKTTQMSAAGTYAWMAPEVIKASTFSKGSDV 305
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WSFGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 306 WSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTL 341
>L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein.
Length = 847
Score = 130 bits (315), Expect = 2e-30
Identities = 69/156 (44%), Positives = 98/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPN 177
N C++ME+ GPL L +G P ++ WA IA+GM YLH +IHRDLKS N
Sbjct: 188 NLCLVMEYAAGGPLSRAL-AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNN 246
Query: 178 VLV-----ADNL---VAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ +D++ K++DFG +REW +++ MS GT AWMAPEVI+ S+ DV
Sbjct: 247 ILLLQPIESDDMEHKTLKITDFGLAREW-HKTTQMSAAGTYAWMAPEVIKASTFSKGSDV 305
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WSFGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 306 WSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTL 341
>BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 130 bits (315), Expect = 2e-30
Identities = 69/156 (44%), Positives = 98/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPN 177
N C++ME+ GPL L +G P ++ WA IA+GM YLH +IHRDLKS N
Sbjct: 188 NLCLVMEYAAGGPLSRAL-AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNN 246
Query: 178 VLV-----ADNL---VAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ +D++ K++DFG +REW +++ MS GT AWMAPEVI+ S+ DV
Sbjct: 247 ILLLQPIESDDMEHKTLKITDFGLAREW-HKTTQMSAAGTYAWMAPEVIKASTFSKGSDV 305
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WSFGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 306 WSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTL 341
>AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 847
Score = 130 bits (315), Expect = 2e-30
Identities = 69/156 (44%), Positives = 98/156 (62%), Gaps = 11/156 (7%)
Frame = +1
Query: 7 NYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPN 177
N C++ME+ GPL L +G P ++ WA IA+GM YLH +IHRDLKS N
Sbjct: 188 NLCLVMEYAAGGPLSRAL-AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNN 246
Query: 178 VLV-----ADNL---VAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDV 333
+L+ +D++ K++DFG +REW +++ MS GT AWMAPEVI+ S+ DV
Sbjct: 247 ILLLQPIESDDMEHKTLKITDFGLAREW-HKTTQMSAAGTYAWMAPEVIKASTFSKGSDV 305
Query: 334 WSFGVVLWELLTQEIPYKTLETHAILWGVGTETILL 441
WSFGV+LWELLT E+PY+ ++ A+ +GV + L
Sbjct: 306 WSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTL 341
>AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 1036
Score = 118 bits (284), Expect = 9e-27
Identities = 58/131 (44%), Positives = 83/131 (63%), Gaps = 11/131 (8%)
Frame = +1
Query: 82 PRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPNVLVAD--------NLVAKVSDFGTS 228
P ++ WA IA+GM+YLH I+HRDLKS N+L+ + N K++DFG +
Sbjct: 234 PHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLA 293
Query: 229 REWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQEIPYKTLETHAI 408
REW + + MS GT AWMAPEVI+ S+ D+WS+GV+LWELLT E+PY+ ++ A+
Sbjct: 294 REW-HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAV 352
Query: 409 LWGVGTETILL 441
+GV + L
Sbjct: 353 AYGVAVNKLTL 363
>AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 570
Score = 118 bits (284), Expect = 9e-27
Identities = 58/131 (44%), Positives = 83/131 (63%), Gaps = 11/131 (8%)
Frame = +1
Query: 82 PRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPNVLVAD--------NLVAKVSDFGTS 228
P ++ WA IA+GM+YLH I+HRDLKS N+L+ + N K++DFG +
Sbjct: 234 PHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLA 293
Query: 229 REWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQEIPYKTLETHAI 408
REW + + MS GT AWMAPEVI+ S+ D+WS+GV+LWELLT E+PY+ ++ A+
Sbjct: 294 REW-HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAV 352
Query: 409 LWGVGTETILL 441
+GV + L
Sbjct: 353 AYGVAVNKLTL 363
>AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4beta
protein.
Length = 1036
Score = 116 bits (279), Expect = 4e-26
Identities = 58/131 (44%), Positives = 82/131 (62%), Gaps = 11/131 (8%)
Frame = +1
Query: 82 PRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPNVLVAD--------NLVAKVSDFGTS 228
P ++ WA IA+GM+YLH I+HRDLKS N+L+ + N K++DFG +
Sbjct: 234 PHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNKTLKITDFGLA 293
Query: 229 REWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQEIPYKTLETHAI 408
REW + + MS GT AWMAPEVI+ S+ D+WS GV+LWELLT E+PY+ ++ A+
Sbjct: 294 REW-HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSCGVLLWELLTGEVPYRGIDGLAV 352
Query: 409 LWGVGTETILL 441
+GV + L
Sbjct: 353 AYGVAVNKLTL 363
>AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase
4alpha protein.
Length = 570
Score = 116 bits (279), Expect = 4e-26
Identities = 58/131 (44%), Positives = 82/131 (62%), Gaps = 11/131 (8%)
Frame = +1
Query: 82 PRQIIRWAKDIAQGMVYLHNRK---IIHRDLKSPNVLVAD--------NLVAKVSDFGTS 228
P ++ WA IA+GM+YLH I+HRDLKS N+L+ + N K++DFG +
Sbjct: 234 PHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNKTLKITDFGLA 293
Query: 229 REWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQEIPYKTLETHAI 408
REW + + MS GT AWMAPEVI+ S+ D+WS GV+LWELLT E+PY+ ++ A+
Sbjct: 294 REW-HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSCGVLLWELLTGEVPYRGIDGLAV 352
Query: 409 LWGVGTETILL 441
+GV + L
Sbjct: 353 AYGVAVNKLTL 363
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 113 bits (272), Expect = 3e-25
Identities = 61/148 (41%), Positives = 86/148 (58%), Gaps = 8/148 (5%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
+N I+ ++C+ LY LH F Q+I A+ AQGM YLH + IIHRD+KS N+
Sbjct: 415 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 474
Query: 181 LVADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIR---HEPCSERVDVWSF 342
+ + L K+ DFG W V TG+V WMAPEVIR + P S + DV+S+
Sbjct: 475 FLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSY 534
Query: 343 GVVLWELLTQEIPYKTLETH-AILWGVG 423
G+VL+EL+T E+PY + I++ VG
Sbjct: 535 GIVLYELMTGELPYSHINNRDQIIFMVG 562
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 113 bits (272), Expect = 3e-25
Identities = 61/148 (41%), Positives = 86/148 (58%), Gaps = 8/148 (5%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
+N I+ ++C+ LY LH F Q+I A+ AQGM YLH + IIHRD+KS N+
Sbjct: 188 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 247
Query: 181 LVADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIR---HEPCSERVDVWSF 342
+ + L K+ DFG W V TG+V WMAPEVIR + P S + DV+S+
Sbjct: 248 FLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSY 307
Query: 343 GVVLWELLTQEIPYKTLETH-AILWGVG 423
G+VL+EL+T E+PY + I++ VG
Sbjct: 308 GIVLYELITGELPYSHINNRDQIIFMVG 335
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 113 bits (272), Expect = 3e-25
Identities = 61/148 (41%), Positives = 86/148 (58%), Gaps = 8/148 (5%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
+N I+ ++C+ LY LH F Q+I A+ AQGM YLH + IIHRD+KS N+
Sbjct: 415 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 474
Query: 181 LVADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIR---HEPCSERVDVWSF 342
+ + L K+ DFG W V TG+V WMAPEVIR + P S + DV+S+
Sbjct: 475 FLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSY 534
Query: 343 GVVLWELLTQEIPYKTLETH-AILWGVG 423
G+VL+EL+T E+PY + I++ VG
Sbjct: 535 GIVLYELMTGELPYSHINNRDQIIFMVG 562
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 113 bits (272), Expect = 3e-25
Identities = 61/148 (41%), Positives = 86/148 (58%), Gaps = 8/148 (5%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
+N I+ ++C+ LY LH F Q+I A+ AQGM YLH + IIHRD+KS N+
Sbjct: 415 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 474
Query: 181 LVADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIR---HEPCSERVDVWSF 342
+ + L K+ DFG W V TG+V WMAPEVIR + P S + DV+S+
Sbjct: 475 FLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSY 534
Query: 343 GVVLWELLTQEIPYKTLETH-AILWGVG 423
G+VL+EL+T E+PY + I++ VG
Sbjct: 535 GIVLYELMTGELPYSHINNRDQIIFMVG 562
>DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121964-4|CAI19611.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121964-3|CAI19612.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kinase
splice variant d protein.
Length = 491
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kinase
1c protein.
Length = 518
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kinase
1b protein.
Length = 606
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kinase
1a protein.
Length = 579
Score = 107 bits (257), Expect = 2e-23
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV SE+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 106 bits (254), Expect = 4e-23
Identities = 56/149 (37%), Positives = 88/149 (59%), Gaps = 9/149 (6%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS---FTPRQIIRWAKDIAQGMVYLHN---RKIIHRDLKSP 174
C++ME+ + G LY+ LH +T + W +QG+ YLH+ + +IHRDLK P
Sbjct: 101 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP 160
Query: 175 NVL-VADNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVV 351
N+L VA V K+ DFGT+ D ++ + + G+ AWMAPEV +E+ DV+S+G++
Sbjct: 161 NLLLVAGGTVLKICDFGTA--CDIQTHMTNNKGSAAWMAPEVFEGSNYNEKCDVFSWGII 218
Query: 352 LWELLTQEIPYKTLETHA--ILWGVGTET 432
LWE++T+ P+ + A I+W V T
Sbjct: 219 LWEVITRRKPFDEIGGPAFRIMWAVHNGT 247
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 105 bits (253), Expect = 5e-23
Identities = 56/144 (38%), Positives = 84/144 (58%), Gaps = 8/144 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ ++C+ LY LH F ++I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 527 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 586
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
+L K+ DFG W +G++ WMAPEVIR + P S + DV++FG+VL
Sbjct: 587 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 646
Query: 355 WELLTQEIPYKTLETH-AILWGVG 423
+EL+T ++PY + I++ VG
Sbjct: 647 YELMTGQLPYSNINNRDQIIFMVG 670
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 105 bits (253), Expect = 5e-23
Identities = 56/144 (38%), Positives = 84/144 (58%), Gaps = 8/144 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ ++C+ LY LH F ++I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 89 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 148
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
+L K+ DFG W +G++ WMAPEVIR + P S + DV++FG+VL
Sbjct: 149 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 208
Query: 355 WELLTQEIPYKTLETH-AILWGVG 423
+EL+T ++PY + I++ VG
Sbjct: 209 YELMTGQLPYSNINNRDQIIFMVG 232
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 105 bits (253), Expect = 5e-23
Identities = 56/144 (38%), Positives = 84/144 (58%), Gaps = 8/144 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ ++C+ LY LH F ++I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 527 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 586
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
+L K+ DFG W +G++ WMAPEVIR + P S + DV++FG+VL
Sbjct: 587 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 646
Query: 355 WELLTQEIPYKTLETH-AILWGVG 423
+EL+T ++PY + I++ VG
Sbjct: 647 YELMTGQLPYSNINNRDQIIFMVG 670
>BC111726-1|AAI11727.1| 656|Homo sapiens MAP3K13 protein protein.
Length = 656
Score = 105 bits (253), Expect = 5e-23
Identities = 45/62 (72%), Positives = 55/62 (88%)
Frame = +1
Query: 256 MSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQEIPYKTLETHAILWGVGTETI 435
MSF GTVAWMAPEVIR+EP SE+VD+WSFGVVLWELLT EIPYK +++ AI+WGVG+ ++
Sbjct: 1 MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL 60
Query: 436 LL 441
L
Sbjct: 61 HL 62
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 105 bits (253), Expect = 5e-23
Identities = 56/144 (38%), Positives = 84/144 (58%), Gaps = 8/144 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ ++C+ LY LH F ++I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 527 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 586
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
+L K+ DFG W +G++ WMAPEVIR + P S + DV++FG+VL
Sbjct: 587 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 646
Query: 355 WELLTQEIPYKTLETH-AILWGVG 423
+EL+T ++PY + I++ VG
Sbjct: 647 YELMTGQLPYSNINNRDQIIFMVG 670
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 105 bits (253), Expect = 5e-23
Identities = 56/144 (38%), Positives = 84/144 (58%), Gaps = 8/144 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ ++C+ LY LH F ++I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 1253 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 1312
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
+L K+ DFG W +G++ WMAPEVIR + P S + DV++FG+VL
Sbjct: 1313 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 1372
Query: 355 WELLTQEIPYKTLETH-AILWGVG 423
+EL+T ++PY + I++ VG
Sbjct: 1373 YELMTGQLPYSNINNRDQIIFMVG 1396
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 105 bits (253), Expect = 5e-23
Identities = 56/144 (38%), Positives = 84/144 (58%), Gaps = 8/144 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ ++C+ LY LH F ++I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 412 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 471
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
+L K+ DFG W +G++ WMAPEVIR + P S + DV++FG+VL
Sbjct: 472 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 531
Query: 355 WELLTQEIPYKTLETH-AILWGVG 423
+EL+T ++PY + I++ VG
Sbjct: 532 YELMTGQLPYSNINNRDQIIFMVG 555
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 103 bits (247), Expect = 3e-22
Identities = 58/138 (42%), Positives = 78/138 (56%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL F+ Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 690 IITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNS 749
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+ + G + W APE I + + DVWSFG+V+WE
Sbjct: 750 NLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWE 809
Query: 361 LLTQ-EIPYKTLETHAIL 411
++T E PY L H ++
Sbjct: 810 VMTYGERPYWELSNHEVM 827
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 103 bits (247), Expect = 3e-22
Identities = 58/138 (42%), Positives = 78/138 (56%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL F+ Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 690 IITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNS 749
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+ + G + W APE I + + DVWSFG+V+WE
Sbjct: 750 NLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWE 809
Query: 361 LLTQ-EIPYKTLETHAIL 411
++T E PY L H ++
Sbjct: 810 VMTYGERPYWELSNHEVM 827
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 103 bits (247), Expect = 3e-22
Identities = 58/138 (42%), Positives = 78/138 (56%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL F+ Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 690 IITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNS 749
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+ + G + W APE I + + DVWSFG+V+WE
Sbjct: 750 NLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWE 809
Query: 361 LLTQ-EIPYKTLETHAIL 411
++T E PY L H ++
Sbjct: 810 VMTYGERPYWELSNHEVM 827
>Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 438 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 498 VLYELMTGSLPY 509
>X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for
A-raf-1 oncogene. ).
Length = 606
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 438 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 498 VLYELMTGSLPY 509
>U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase
protein.
Length = 606
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 438 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 498 VLYELMTGSLPY 509
>L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein.
Length = 606
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 438 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 498 VLYELMTGSLPY 509
>BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog 1 protein.
Length = 606
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 438 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 498 VLYELMTGSLPY 509
>BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein.
Length = 609
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 381 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 440
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 441 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 500
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 501 VLYELMTGSLPY 512
>BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 103 bits (246), Expect = 4e-22
Identities = 55/132 (41%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLV 186
+ II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ +
Sbjct: 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query: 187 ADNLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGV 348
+ L K+ DFG W + +G+V WMA EVIR + P S + DV+++GV
Sbjct: 438 HEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query: 349 VLWELLTQEIPY 384
VL+EL+T +PY
Sbjct: 498 VLYELMTGSLPY 509
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 101 bits (242), Expect = 1e-21
Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 5/143 (3%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
C++ EF ++G L D+L + F ++ D+ +GM YL +IHRDL + N LV
Sbjct: 432 CLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVG 491
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGT---VAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
+N V KVSDFG +R + + S TGT V W +PEV S + DVWSFGV++WE
Sbjct: 492 ENQVIKVSDFGMTR-FVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWE 550
Query: 361 LLTQ-EIPYKTLETHAILWGVGT 426
+ ++ +IPY+ ++ + T
Sbjct: 551 VFSEGKIPYENRSNSEVVEDIST 573
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 101 bits (242), Expect = 1e-21
Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 5/143 (3%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
C++ EF ++G L D+L + F ++ D+ +GM YL +IHRDL + N LV
Sbjct: 432 CLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVG 491
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGT---VAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
+N V KVSDFG +R + + S TGT V W +PEV S + DVWSFGV++WE
Sbjct: 492 ENQVIKVSDFGMTR-FVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWE 550
Query: 361 LLTQ-EIPYKTLETHAILWGVGT 426
+ ++ +IPY+ ++ + T
Sbjct: 551 VFSEGKIPYENRSNSEVVEDIST 573
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 101 bits (242), Expect = 1e-21
Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 5/143 (3%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
C++ EF ++G L D+L + F ++ D+ +GM YL +IHRDL + N LV
Sbjct: 432 CLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVG 491
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGT---VAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
+N V KVSDFG +R + + S TGT V W +PEV S + DVWSFGV++WE
Sbjct: 492 ENQVIKVSDFGMTR-FVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWE 550
Query: 361 LLTQ-EIPYKTLETHAILWGVGT 426
+ ++ +IPY+ ++ + T
Sbjct: 551 VFSEGKIPYENRSNSEVVEDIST 573
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 101 bits (242), Expect = 1e-21
Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 5/143 (3%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
C++ EF ++G L D+L + F ++ D+ +GM YL +IHRDL + N LV
Sbjct: 432 CLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVG 491
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGT---VAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
+N V KVSDFG +R + + S TGT V W +PEV S + DVWSFGV++WE
Sbjct: 492 ENQVIKVSDFGMTR-FVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWE 550
Query: 361 LLTQ-EIPYKTLETHAILWGVGT 426
+ ++ +IPY+ ++ + T
Sbjct: 551 VFSEGKIPYENRSNSEVVEDIST 573
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 101 bits (242), Expect = 1e-21
Identities = 53/143 (37%), Positives = 81/143 (56%), Gaps = 5/143 (3%)
Frame = +1
Query: 13 CIIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
C++ EF ++G L D+L + F ++ D+ +GM YL +IHRDL + N LV
Sbjct: 432 CLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVG 491
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGT---VAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
+N V KVSDFG +R + + S TGT V W +PEV S + DVWSFGV++WE
Sbjct: 492 ENQVIKVSDFGMTR-FVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWE 550
Query: 361 LLTQ-EIPYKTLETHAILWGVGT 426
+ ++ +IPY+ ++ + T
Sbjct: 551 VFSEGKIPYENRSNSEVVEDIST 573
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 704 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 762
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 763 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 822
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 823 GIVMWEVMSYGERPYWDMSNQDVI 846
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 704 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 762
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 763 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 822
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 823 GIVMWEVMSYGERPYWDMSNQDVI 846
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 704 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 762
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 763 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 822
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 823 GIVMWEVMSYGERPYWDMSNQDVI 846
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 704 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 762
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 763 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 822
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 823 GIVMWEVMSYGERPYWDMSNQDVI 846
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 704 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 762
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 763 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 822
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 823 GIVMWEVMSYGERPYWDMSNQDVI 846
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 704 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 762
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 763 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 822
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 823 GIVMWEVMSYGERPYWDMSNQDVI 846
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 101 bits (241), Expect = 1e-21
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 7/144 (4%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
G+ I++EF + G L FL H G FT Q++ + IA GM YL + +HRDL +
Sbjct: 706 GKPVMIVIEFMENGALDAFLRKHDG-QFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAAR 764
Query: 175 NVLVADNLVAKVSDFGTSRE-WDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSF 342
N+LV NLV KVSDFG SR D+ AV + TG V W APE I++ + DVWS+
Sbjct: 765 NILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSY 824
Query: 343 GVVLWELLTQ-EIPYKTLETHAIL 411
G+V+WE+++ E PY + ++
Sbjct: 825 GIVMWEVMSYGERPYWDMSNQDVI 848
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 99.1 bits (236), Expect = 6e-21
Identities = 50/126 (39%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ +A+GM YL ++K++HRDL + N+LV+
Sbjct: 302 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVS 361
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 362 EDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
Query: 370 Q-EIPY 384
PY
Sbjct: 420 YGRAPY 425
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 99.1 bits (236), Expect = 6e-21
Identities = 50/126 (39%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ +A+GM YL ++K++HRDL + N+LV+
Sbjct: 302 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVS 361
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 362 EDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
Query: 370 Q-EIPY 384
PY
Sbjct: 420 YGRAPY 425
>M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein.
Length = 298
Score = 99.1 bits (236), Expect = 6e-21
Identities = 54/130 (41%), Positives = 75/130 (57%), Gaps = 7/130 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II ++C+ LY LH + F Q+I A+ AQGM YLH + IIHRDLKS N+ + +
Sbjct: 89 IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHE 148
Query: 193 NLVAKVSDFG---TSREWDNESAVMSFTGTVAWMAPEVIRHE---PCSERVDVWSFGVVL 354
L K+ DFG W + +G V WMA EV R + P S + DV+++GVVL
Sbjct: 149 GLTVKIGDFGLATVKTRWSGAQPLEQPSGPVLWMAAEVTRMQDPNPYSFQSDVYAYGVVL 208
Query: 355 WELLTQEIPY 384
+EL+T +PY
Sbjct: 209 YELMTGSLPY 218
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 99.1 bits (236), Expect = 6e-21
Identities = 50/126 (39%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ +A+GM YL ++K++HRDL + N+LV+
Sbjct: 302 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVS 361
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 362 EDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
Query: 370 Q-EIPY 384
PY
Sbjct: 420 YGRAPY 425
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 99.1 bits (236), Expect = 6e-21
Identities = 50/126 (39%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ +A+GM YL ++K++HRDL + N+LV+
Sbjct: 302 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVS 361
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 362 EDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
Query: 370 Q-EIPY 384
PY
Sbjct: 420 YGRAPY 425
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 99.1 bits (236), Expect = 6e-21
Identities = 50/126 (39%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ +A+GM YL ++K++HRDL + N+LV+
Sbjct: 302 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVS 361
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 362 EDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
Query: 370 Q-EIPY 384
PY
Sbjct: 420 YGRAPY 425
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 98.7 bits (235), Expect = 8e-21
Identities = 46/128 (35%), Positives = 82/128 (64%), Gaps = 4/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME+C G L ++ G F+ QI+ W I+ G+ ++H+RKI+HRD+K+ N+ ++
Sbjct: 78 IVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLS 137
Query: 190 DN-LVAKVSDFGTSREWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
N +VAK+ DFG +R +N + GT +++PE+ +++P + + D+WS G VL+EL
Sbjct: 138 KNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYEL 197
Query: 364 LTQEIPYK 387
T + P++
Sbjct: 198 CTLKHPFE 205
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 98.7 bits (235), Expect = 8e-21
Identities = 46/128 (35%), Positives = 82/128 (64%), Gaps = 4/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME+C G L ++ G F+ QI+ W I+ G+ ++H+RKI+HRD+K+ N+ ++
Sbjct: 78 IVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLS 137
Query: 190 DN-LVAKVSDFGTSREWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
N +VAK+ DFG +R +N + GT +++PE+ +++P + + D+WS G VL+EL
Sbjct: 138 KNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYEL 197
Query: 364 LTQEIPYK 387
T + P++
Sbjct: 198 CTLKHPFE 205
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 97.9 bits (233), Expect = 1e-20
Identities = 54/128 (42%), Positives = 78/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GMV++ R IHRDL++ N+LV+
Sbjct: 317 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMVFIEERNYIHRDLRAANILVS 376
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 377 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 436
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 437 VTHGRIPY 444
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 97.9 bits (233), Expect = 1e-20
Identities = 55/141 (39%), Positives = 80/141 (56%), Gaps = 6/141 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ E+ + G L FL A FT Q++ + IA GM YL + +HRDL + N+L+
Sbjct: 697 IVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W +PE I + + DVWS+G+VLWE
Sbjct: 757 NLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWE 816
Query: 361 LLTQ-EIPYKTLETHAILWGV 420
+++ E PY + ++ V
Sbjct: 817 VMSYGERPYWEMSNQDVIKAV 837
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 698 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 757
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 758 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 817
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 818 WEVMSYGERPY 828
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 681 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 740
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 741 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKFPIRWTAPEAIQYRKFTSASDVWSYGIVM 800
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 801 WEVMSYGERPY 811
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 189 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 248
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 249 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 308
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 309 WEVMSYGERPY 319
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 692 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 751
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 752 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 811
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 812 WEVMSYGERPY 822
>D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein.
Length = 347
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 58 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 117
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 118 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 177
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 178 WEVMSYGERPY 188
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 97.9 bits (233), Expect = 1e-20
Identities = 55/141 (39%), Positives = 80/141 (56%), Gaps = 6/141 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ E+ + G L FL A FT Q++ + IA GM YL + +HRDL + N+L+
Sbjct: 697 IVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W +PE I + + DVWS+G+VLWE
Sbjct: 757 NLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWE 816
Query: 361 LLTQ-EIPYKTLETHAILWGV 420
+++ E PY + ++ V
Sbjct: 817 VMSYGERPYWEMSNQDVIKAV 837
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 698 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 757
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 758 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 817
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 818 WEVMSYGERPY 828
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 692 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 751
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 752 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 811
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 812 WEVMSYGERPY 822
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 698 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 757
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 758 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 817
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 818 WEVMSYGERPY 828
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 698 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 757
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 758 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 817
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 818 WEVMSYGERPY 828
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 692 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 751
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 752 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 811
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 812 WEVMSYGERPY 822
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 97.9 bits (233), Expect = 1e-20
Identities = 55/141 (39%), Positives = 80/141 (56%), Gaps = 6/141 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ E+ + G L FL A FT Q++ + IA GM YL + +HRDL + N+L+
Sbjct: 697 IVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W +PE I + + DVWS+G+VLWE
Sbjct: 757 NLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWE 816
Query: 361 LLTQ-EIPYKTLETHAILWGV 420
+++ E PY + ++ V
Sbjct: 817 VMSYGERPYWEMSNQDVIKAV 837
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 757 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 817 WEVMSYGERPY 827
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 97.9 bits (233), Expect = 1e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL + +HRDL + N+LV
Sbjct: 715 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 774
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++++ ++T + W APE I++ + DVWS+G+V+
Sbjct: 775 NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 834
Query: 355 WELLTQ-EIPY 384
WE+++ E PY
Sbjct: 835 WEVMSYGERPY 845
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 97.1 bits (231), Expect = 2e-20
Identities = 53/137 (38%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL P Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 415 IITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ 474
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
NL KVSDFG +R D+ G + W APE I H + DVWSFG+V+WE+
Sbjct: 475 NLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 534
Query: 364 LT-QEIPYKTLETHAIL 411
L+ + PY + ++
Sbjct: 535 LSFGDKPYGEMSNQEVM 551
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 97.1 bits (231), Expect = 2e-20
Identities = 53/140 (37%), Positives = 78/140 (55%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 695 IITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNS 754
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR ++++ ++T + V W APE I + + DVWS+G+V+
Sbjct: 755 NLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVM 814
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 815 WEVMSFGERPYWDMSNQDVI 834
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 97.1 bits (231), Expect = 2e-20
Identities = 53/137 (38%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL P Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 700 IITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ 759
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
NL KVSDFG +R D+ G + W APE I H + DVWSFG+V+WE+
Sbjct: 760 NLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 819
Query: 364 LT-QEIPYKTLETHAIL 411
L+ + PY + ++
Sbjct: 820 LSFGDKPYGEMSNQEVM 836
>AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein.
Length = 1005
Score = 97.1 bits (231), Expect = 2e-20
Identities = 59/142 (41%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ + G L FL H G FT Q++ + + GM YL + +HRDL + NVLV
Sbjct: 711 IVTEYMENGSLDTFLRTHDG-QFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVD 769
Query: 190 DNLVAKVSDFGTSREW-DNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
NLV KVSDFG SR D+ A + TG + W APE I S DVWSFGVV+W
Sbjct: 770 SNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMW 829
Query: 358 ELLTQ-EIPYKTLETHAILWGV 420
E+L E PY + ++ V
Sbjct: 830 EVLAYGERPYWNMTNRDVISSV 851
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 97.1 bits (231), Expect = 2e-20
Identities = 53/137 (38%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL P Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 700 IITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ 759
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
NL KVSDFG +R D+ G + W APE I H + DVWSFG+V+WE+
Sbjct: 760 NLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 819
Query: 364 LT-QEIPYKTLETHAIL 411
L+ + PY + ++
Sbjct: 820 LSFGDKPYGEMSNQEVM 836
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 97.1 bits (231), Expect = 2e-20
Identities = 53/137 (38%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL P Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 700 IITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ 759
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
NL KVSDFG +R D+ G + W APE I H + DVWSFG+V+WE+
Sbjct: 760 NLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 819
Query: 364 LT-QEIPYKTLETHAIL 411
L+ + PY + ++
Sbjct: 820 LSFGDKPYGEMSNQEVM 836
>AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein.
Length = 853
Score = 97.1 bits (231), Expect = 2e-20
Identities = 59/142 (41%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ + G L FL H G FT Q++ + + GM YL + +HRDL + NVLV
Sbjct: 559 IVTEYMENGSLDTFLRTHDG-QFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVD 617
Query: 190 DNLVAKVSDFGTSREW-DNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
NLV KVSDFG SR D+ A + TG + W APE I S DVWSFGVV+W
Sbjct: 618 SNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMW 677
Query: 358 ELLTQ-EIPYKTLETHAILWGV 420
E+L E PY + ++ V
Sbjct: 678 EVLAYGERPYWNMTNRDVISSV 699
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 96.7 bits (230), Expect = 3e-20
Identities = 49/126 (38%), Positives = 77/126 (61%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ + +GM YL ++K++HRDL + N+LV+
Sbjct: 260 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVREGMEYLESKKLVHRDLAARNILVS 319
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
+ LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 320 EELVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 377
Query: 370 Q-EIPY 384
PY
Sbjct: 378 YGRAPY 383
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 96.7 bits (230), Expect = 3e-20
Identities = 47/125 (37%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A G+ +LH+ II+RDLK N+L+ +
Sbjct: 139 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEE 198
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ + S D WS+GV+++E+LT
Sbjct: 199 GHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTG 258
Query: 373 EIPYK 387
+P++
Sbjct: 259 SLPFQ 263
Score = 67.7 bits (158), Expect = 2e-11
Identities = 37/133 (27%), Positives = 71/133 (53%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G++ ++ E + G L D + F+ R+ I + + YLH++ ++HRDLK N+
Sbjct: 482 GKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNI 541
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + E D+WS G
Sbjct: 542 LYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLG 601
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 602 ILLYTMLAGYTPF 614
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 96.7 bits (230), Expect = 3e-20
Identities = 47/125 (37%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A G+ +LH+ II+RDLK N+L+ +
Sbjct: 139 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEE 198
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ + S D WS+GV+++E+LT
Sbjct: 199 GHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTG 258
Query: 373 EIPYK 387
+P++
Sbjct: 259 SLPFQ 263
Score = 67.7 bits (158), Expect = 2e-11
Identities = 37/133 (27%), Positives = 71/133 (53%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G++ ++ E + G L D + F+ R+ I + + YLH++ ++HRDLK N+
Sbjct: 482 GKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNI 541
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + E D+WS G
Sbjct: 542 LYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLG 601
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 602 ILLYTMLAGYTPF 614
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 96.7 bits (230), Expect = 3e-20
Identities = 47/125 (37%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A G+ +LH+ II+RDLK N+L+ +
Sbjct: 139 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEE 198
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ + S D WS+GV+++E+LT
Sbjct: 199 GHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTG 258
Query: 373 EIPYK 387
+P++
Sbjct: 259 SLPFQ 263
Score = 67.7 bits (158), Expect = 2e-11
Identities = 37/133 (27%), Positives = 71/133 (53%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G++ ++ E + G L D + F+ R+ I + + YLH++ ++HRDLK N+
Sbjct: 482 GKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNI 541
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + E D+WS G
Sbjct: 542 LYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLG 601
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 602 ILLYTMLAGYTPF 614
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 314 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 373
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 374 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 433
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 434 VTHGRIPY 441
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 314 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 373
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 374 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 433
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 434 VTHGRIPY 441
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 315 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 374
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 375 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 434
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 435 VTHGRIPY 442
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 314 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 373
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 374 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 433
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 434 VTHGRIPY 441
>AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 301 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 360
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 361 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 420
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 421 VTHGRIPY 428
>AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene
tyrosine-protein kinase LCK protein.
Length = 516
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 321 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 380
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 381 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 440
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 441 VTHGRIPY 448
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 96.3 bits (229), Expect = 4e-20
Identities = 53/128 (41%), Positives = 77/128 (60%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ + G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+
Sbjct: 301 IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 360
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
D L K++DFG +R DNE +A + W APE I + + + DVWSFG++L E+
Sbjct: 361 DTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 420
Query: 364 LTQ-EIPY 384
+T IPY
Sbjct: 421 VTHGRIPY 428
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 95.9 bits (228), Expect = 6e-20
Identities = 52/140 (37%), Positives = 78/140 (55%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL +HRDL + N+L+
Sbjct: 695 IITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILLNS 754
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR ++++ ++T + V W APE I + + DVWS+G+V+
Sbjct: 755 NLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVM 814
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 815 WEVMSFGERPYWDMSNQDVI 834
>BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein.
Length = 482
Score = 95.9 bits (228), Expect = 6e-20
Identities = 47/125 (37%), Positives = 74/125 (59%), Gaps = 5/125 (4%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYD----FLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKS 171
+N+CII E+C+ L D + +G F QII W + G+ Y+H R+I+HRDLKS
Sbjct: 102 DNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKS 161
Query: 172 PNVLVADNLVAKVSDFGTSR-EWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGV 348
NV + +NL+ K+ DFG SR + + TGT +M+PE ++H+ + D+WS
Sbjct: 162 KNVFLKNNLL-KIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLAC 220
Query: 349 VLWEL 363
+L+E+
Sbjct: 221 ILYEM 225
>AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S
protein.
Length = 470
Score = 95.9 bits (228), Expect = 6e-20
Identities = 47/125 (37%), Positives = 74/125 (59%), Gaps = 5/125 (4%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYD----FLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKS 171
+N+CII E+C+ L D + +G F QII W + G+ Y+H R+I+HRDLKS
Sbjct: 102 DNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKS 161
Query: 172 PNVLVADNLVAKVSDFGTSR-EWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGV 348
NV + +NL+ K+ DFG SR + + TGT +M+PE ++H+ + D+WS
Sbjct: 162 KNVFLKNNLL-KIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLAC 220
Query: 349 VLWEL 363
+L+E+
Sbjct: 221 ILYEM 225
>AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L
protein.
Length = 645
Score = 95.9 bits (228), Expect = 6e-20
Identities = 47/125 (37%), Positives = 74/125 (59%), Gaps = 5/125 (4%)
Frame = +1
Query: 4 ENYCIIMEFCQYGPLYD----FLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKS 171
+N+CII E+C+ L D + +G F QII W + G+ Y+H R+I+HRDLKS
Sbjct: 102 DNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKS 161
Query: 172 PNVLVADNLVAKVSDFGTSR-EWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGV 348
NV + +NL+ K+ DFG SR + + TGT +M+PE ++H+ + D+WS
Sbjct: 162 KNVFLKNNLL-KIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLAC 220
Query: 349 VLWEL 363
+L+E+
Sbjct: 221 ILYEM 225
>L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 986
Score = 95.5 bits (227), Expect = 7e-20
Identities = 54/138 (39%), Positives = 77/138 (55%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL FT Q++ + I GM YL + +HRDL + N+LV
Sbjct: 697 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + + DVWS+G+V+WE
Sbjct: 757 NLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWE 816
Query: 361 LLTQ-EIPYKTLETHAIL 411
+++ E PY + ++
Sbjct: 817 VMSYGERPYWDMSNQDVI 834
>BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4
protein.
Length = 986
Score = 95.5 bits (227), Expect = 7e-20
Identities = 54/138 (39%), Positives = 77/138 (55%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL FT Q++ + I GM YL + +HRDL + N+LV
Sbjct: 697 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + + DVWS+G+V+WE
Sbjct: 757 NLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWE 816
Query: 361 LLTQ-EIPYKTLETHAIL 411
+++ E PY + ++
Sbjct: 817 VMSYGERPYWDMSNQDVI 834
>BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein.
Length = 986
Score = 95.5 bits (227), Expect = 7e-20
Identities = 54/138 (39%), Positives = 77/138 (55%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL FT Q++ + I GM YL + +HRDL + N+LV
Sbjct: 697 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + + DVWS+G+V+WE
Sbjct: 757 NLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWE 816
Query: 361 LLTQ-EIPYKTLETHAIL 411
+++ E PY + ++
Sbjct: 817 VMSYGERPYWDMSNQDVI 834
>BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein.
Length = 949
Score = 95.5 bits (227), Expect = 7e-20
Identities = 54/138 (39%), Positives = 77/138 (55%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL FT Q++ + I GM YL + +HRDL + N+LV
Sbjct: 697 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNS 756
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + + DVWS+G+V+WE
Sbjct: 757 NLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWE 816
Query: 361 LLTQ-EIPYKTLETHAIL 411
+++ E PY + ++
Sbjct: 817 VMSYGERPYWDMSNQDVI 834
>AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein.
Length = 711
Score = 95.5 bits (227), Expect = 7e-20
Identities = 54/138 (39%), Positives = 77/138 (55%), Gaps = 6/138 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II E+ + G L FL FT Q++ + I GM YL + +HRDL + N+LV
Sbjct: 422 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNS 481
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + + DVWS+G+V+WE
Sbjct: 482 NLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWE 541
Query: 361 LLTQ-EIPYKTLETHAIL 411
+++ E PY + ++
Sbjct: 542 VMSYGERPYWDMSNQDVI 559
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 95.1 bits (226), Expect = 1e-19
Identities = 50/126 (39%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG--ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ME G L +FL + A Q+++++ +A+GM YL ++K++HRDL + N+LV+
Sbjct: 302 IVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVS 361
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++LVAKVSDFG ++ + S V W APE ++H + + DVWSFGV+LWE+ +
Sbjct: 362 EDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTAPEALKH-GFTSKSDVWSFGVLLWEVFS 418
Query: 370 Q-EIPY 384
PY
Sbjct: 419 YGRAPY 424
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 94.7 bits (225), Expect = 1e-19
Identities = 52/137 (37%), Positives = 71/137 (51%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + L FL P Q++ + IA GM YL N +HRDL + N+LV
Sbjct: 708 IITEFMENAALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ 767
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTG---TVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
NL KVSDFG +R D+ G + W APE I H + DVWSFG+V+WE+
Sbjct: 768 NLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 827
Query: 364 LT-QEIPYKTLETHAIL 411
L+ + PY + ++
Sbjct: 828 LSFGDKPYGEMSNQEVM 844
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens
cDNA FLJ90626 fis, clone PLACE1003135, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 339
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 15 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 73
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 74 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 133
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 134 ELAKGEPPNSDMHPMRVLF 152
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 94.3 bits (224), Expect = 2e-19
Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 684 IITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNS 743
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR ++++ ++T + V W APE I + + DVWS+G+ +
Sbjct: 744 NLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIRM 803
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 804 WEVMSFGERPYWDMSNQDVI 823
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 94.3 bits (224), Expect = 2e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G IIME+ G D L +G F QI K+I +G+ YLH+ K IHRD+K+ NV
Sbjct: 92 GSKLWIIMEYLGGGSALDLLRAGP-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 181 LVADNLVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLW 357
L+++ K++DFG + + D + +F GT WMAPEVI+ + D+WS G+
Sbjct: 151 LLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210
Query: 358 ELLTQEIPYKTLETHAILW 414
EL E P + +L+
Sbjct: 211 ELAKGEPPNSDMHPMRVLF 229
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 205 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264
Query: 373 EIPYK 387
+P++
Sbjct: 265 TLPFQ 269
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 486 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 545
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 546 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 605
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 606 VLLYTMLTGYTPF 618
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 144 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 203
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 204 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 263
Query: 373 EIPYK 387
+P++
Sbjct: 264 TLPFQ 268
Score = 37.9 bits (84), Expect = 0.016
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +1
Query: 10 YCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
Y ++ + G L D + F+ R+ I + + YLH + ++HRDLK N+L
Sbjct: 487 YVYVVTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYV 546
Query: 190 DNL----VAKVSDFGTSREWDNESAVM 258
D ++ DFG +++ E+ ++
Sbjct: 547 DESGNPESIRICDFGFAKQLRAENGLL 573
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 205 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264
Query: 373 EIPYK 387
+P++
Sbjct: 265 TLPFQ 269
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 486 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 545
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 546 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 605
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 606 VLLYTMLTGYTPF 618
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 205 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264
Query: 373 EIPYK 387
+P++
Sbjct: 265 TLPFQ 269
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 486 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 545
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 546 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 605
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 606 VLLYTMLTGYTPF 618
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 205 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264
Query: 373 EIPYK 387
+P++
Sbjct: 265 TLPFQ 269
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 486 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 545
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 546 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 605
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 606 VLLYTMLTGYTPF 618
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 205 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264
Query: 373 EIPYK 387
+P++
Sbjct: 265 TLPFQ 269
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 486 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 545
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 546 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 605
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 606 VLLYTMLTGYTPF 618
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 205 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264
Query: 373 EIPYK 387
+P++
Sbjct: 265 TLPFQ 269
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 486 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 545
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 546 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 605
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 606 VLLYTMLTGYTPF 618
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 212 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 271
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 272 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 331
Query: 373 EIPYK 387
+P++
Sbjct: 332 TLPFQ 336
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 552 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 611
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 612 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 671
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 672 VLLYTMLTGYTPF 684
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 93.9 bits (223), Expect = 2e-19
Identities = 46/125 (36%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 131 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 190
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D+E SF GTV +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 191 GHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 250
Query: 373 EIPYK 387
+P++
Sbjct: 251 TLPFQ 255
Score = 65.7 bits (153), Expect = 7e-11
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ E + G L D + F+ R+ I + + YLH + ++HRDLK N+
Sbjct: 472 GKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNI 531
Query: 181 LVADNL----VAKVSDFGTSREWDNESA-VMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D ++ DFG +++ E+ +M+ T ++APEV++ + D+WS G
Sbjct: 532 LYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 591
Query: 346 VVLWELLTQEIPY 384
V+L+ +LT P+
Sbjct: 592 VLLYTMLTGYTPF 604
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 93.5 bits (222), Expect = 3e-19
Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 136 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 195
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D++ SF GT+ +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 196 GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 255
Query: 373 EIPYK 387
+P++
Sbjct: 256 SLPFQ 260
Score = 64.9 bits (151), Expect = 1e-10
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ME + G L D + F+ R+ I + M YLH++ ++HRDLK N+
Sbjct: 479 GKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNI 538
Query: 181 LVADNLVA----KVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D + +V DFG +++ +M+ T ++APEV++ + D+WS G
Sbjct: 539 LYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 598
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 599 ILLYTMLAGFTPF 611
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 93.5 bits (222), Expect = 3e-19
Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 136 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 195
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D++ SF GT+ +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 196 GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 255
Query: 373 EIPYK 387
+P++
Sbjct: 256 SLPFQ 260
Score = 64.9 bits (151), Expect = 1e-10
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ME + G L D + F+ R+ I + M YLH++ ++HRDLK N+
Sbjct: 479 GKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNI 538
Query: 181 LVADNLVA----KVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D + +V DFG +++ +M+ T ++APEV++ + D+WS G
Sbjct: 539 LYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 598
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 599 ILLYTMLAGFTPF 611
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 691 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 750
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 751 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 810
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 811 WEVMSFGERPYWDMSNQDVI 830
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 691 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 750
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 751 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 810
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 811 WEVMSFGERPYWDMSNQDVI 830
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 549 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 608
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 609 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 668
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 669 WEVMSFGERPYWDMSNQDVI 688
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 93.5 bits (222), Expect = 3e-19
Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 136 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 195
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D++ SF GT+ +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 196 GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 255
Query: 373 EIPYK 387
+P++
Sbjct: 256 SLPFQ 260
Score = 64.9 bits (151), Expect = 1e-10
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ME + G L D + F+ R+ I + M YLH++ ++HRDLK N+
Sbjct: 479 GKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNI 538
Query: 181 LVADNLVA----KVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D + +V DFG +++ +M+ T ++APEV++ + D+WS G
Sbjct: 539 LYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 598
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 599 ILLYTMLAGFTPF 611
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 691 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 750
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 751 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 810
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 811 WEVMSFGERPYWDMSNQDVI 830
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 691 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 750
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 751 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 810
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 811 WEVMSFGERPYWDMSNQDVI 830
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 93.5 bits (222), Expect = 3e-19
Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 136 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 195
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D++ SF GT+ +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 196 GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 255
Query: 373 EIPYK 387
+P++
Sbjct: 256 SLPFQ 260
Score = 64.9 bits (151), Expect = 1e-10
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ME + G L D + F+ R+ I + M YLH++ ++HRDLK N+
Sbjct: 479 GKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNI 538
Query: 181 LVADNLVA----KVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D + +V DFG +++ +M+ T ++APEV++ + D+WS G
Sbjct: 539 LYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 598
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 599 ILLYTMLAGFTPF 611
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 691 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 750
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 751 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 810
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 811 WEVMSFGERPYWDMSNQDVI 830
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + G L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 690 ILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNS 749
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR + S+ ++T + + W APE I + D WS+G+V+
Sbjct: 750 NLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVM 809
Query: 355 WELLT-QEIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 810 WEVMSFGERPYWDMSNQDVI 829
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 93.5 bits (222), Expect = 3e-19
Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 209 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 268
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D++ SF GT+ +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 269 GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 328
Query: 373 EIPYK 387
+P++
Sbjct: 329 SLPFQ 333
Score = 64.9 bits (151), Expect = 1e-10
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ME + G L D + F+ R+ I + M YLH++ ++HRDLK N+
Sbjct: 552 GKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNI 611
Query: 181 LVADNLVA----KVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFG 345
L D + +V DFG +++ +M+ T ++APEV++ + D+WS G
Sbjct: 612 LYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLG 671
Query: 346 VVLWELLTQEIPY 384
++L+ +L P+
Sbjct: 672 ILLYTMLAGFTPF 684
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 296 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 355
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 356 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 415
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 416 VTYGKIPY 423
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 317 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 376
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 377 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 436
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 437 VTYGKIPY 444
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 93.1 bits (221), Expect = 4e-19
Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
+I++F + G L+ L FT + + ++A + +LH+ II+RDLK N+L+ +
Sbjct: 137 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 196
Query: 196 LVAKVSDFGTSREW-DNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG S+E D++ SF GT+ +MAPEV+ ++ D WSFGV+++E+LT
Sbjct: 197 GHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 256
Query: 373 EIPYK 387
+P++
Sbjct: 257 ALPFQ 261
Score = 38.7 bits (86), Expect = 0.009
Identities = 20/61 (32%), Positives = 33/61 (54%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNV 180
G+ ++ME + G L D + F+ R+ I + M YLH++ ++HRDLK N+
Sbjct: 480 GKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNI 539
Query: 181 L 183
L
Sbjct: 540 L 540
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 317 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 376
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 377 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 436
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 437 VTYGKIPY 444
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 317 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 376
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 377 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 436
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 437 VTYGKIPY 444
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 317 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 376
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 377 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 436
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 437 VTYGKIPY 444
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 317 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 376
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 377 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 436
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 437 VTYGKIPY 444
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 387 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 446
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 447 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 506
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 507 VTYGKIPY 514
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/128 (40%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E+ G L DFL S G ++I ++ IA+GM Y+ + IHRDL++ NVLV+
Sbjct: 387 IITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVS 446
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
++L+ K++DFG +R DNE +A + W APE I + + DVWSFG++L+E+
Sbjct: 447 ESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEI 506
Query: 364 LTQ-EIPY 384
+T +IPY
Sbjct: 507 VTYGKIPY 514
>AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1c protein.
Length = 943
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 654 IITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNS 713
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR ++++ ++T + V W APE I + + DVWS+G+ +
Sbjct: 714 NLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIHM 773
Query: 355 WELL-TQEIPYKTLETHAIL 411
WE++ E PY + ++
Sbjct: 774 WEVMYFGERPYWDMSNQDVI 793
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 93.1 bits (221), Expect = 4e-19
Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
II EF + G L FL FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 695 IITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNS 754
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR ++++ ++T + V W APE I + + DVWS+G+ +
Sbjct: 755 NLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIHM 814
Query: 355 WELL-TQEIPYKTLETHAIL 411
WE++ E PY + ++
Sbjct: 815 WEVMYFGERPYWDMSNQDVI 834
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine kinase
protein.
Length = 1037
Score = 92.7 bits (220), Expect = 5e-19
Identities = 53/141 (37%), Positives = 78/141 (55%), Gaps = 6/141 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ E+ + G L FL FT Q++ + I+ GM YL + +HRDL + N+L+
Sbjct: 751 IVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINS 810
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + DVWS+G+V+WE
Sbjct: 811 NLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWE 870
Query: 361 LLTQ-EIPYKTLETHAILWGV 420
+++ E PY + ++ V
Sbjct: 871 VVSYGERPYWEMTNQDVIKAV 891
>X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine
kinase-receptor protein.
Length = 998
Score = 92.7 bits (220), Expect = 5e-19
Identities = 50/140 (35%), Positives = 78/140 (55%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 709 ILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNS 768
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++ + ++T + + W APE I + + DVWS+G+V+
Sbjct: 769 NLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM 828
Query: 355 WELLTQ-EIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 829 WEVMSYGERPYWDMSNQDVI 848
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 92.7 bits (220), Expect = 5e-19
Identities = 53/141 (37%), Positives = 78/141 (55%), Gaps = 6/141 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ E+ + G L FL FT Q++ + I+ GM YL + +HRDL + N+L+
Sbjct: 705 IVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINS 764
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + DVWS+G+V+WE
Sbjct: 765 NLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWE 824
Query: 361 LLTQ-EIPYKTLETHAILWGV 420
+++ E PY + ++ V
Sbjct: 825 VVSYGERPYWEMTNQDVIKAV 845
>BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein.
Length = 998
Score = 92.7 bits (220), Expect = 5e-19
Identities = 50/140 (35%), Positives = 78/140 (55%), Gaps = 8/140 (5%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLH-SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ EF + L FL + FT Q++ + IA GM YL +HRDL + N+LV
Sbjct: 709 ILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNS 768
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTGT------VAWMAPEVIRHEPCSERVDVWSFGVVL 354
NLV KVSDFG SR +++ + ++T + + W APE I + + DVWS+G+V+
Sbjct: 769 NLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM 828
Query: 355 WELLTQ-EIPYKTLETHAIL 411
WE+++ E PY + ++
Sbjct: 829 WEVMSYGERPYWDMSNQDVI 848
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 92.7 bits (220), Expect = 5e-19
Identities = 53/141 (37%), Positives = 78/141 (55%), Gaps = 6/141 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSG-ASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
I+ E+ + G L FL FT Q++ + I+ GM YL + +HRDL + N+L+
Sbjct: 765 IVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINS 824
Query: 193 NLVAKVSDFGTSR--EWDNESAVMSFTG--TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
NLV KVSDFG SR E D E+A + G + W APE I + DVWS+G+V+WE
Sbjct: 825 NLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWE 884
Query: 361 LLTQ-EIPYKTLETHAILWGV 420
+++ E PY + ++ V
Sbjct: 885 VVSYGERPYWEMTNQDVIKAV 905
>X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase
protein.
Length = 1138
Score = 92.3 bits (219), Expect = 7e-19
Identities = 56/136 (41%), Positives = 77/136 (56%), Gaps = 18/136 (13%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL---------------HSGAS-FTPRQIIRWAKDIAQGMVYLHNRK 147
I +E+ YG L DFL H AS + RQ++R+A D A GM YL ++
Sbjct: 915 IAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQ 974
Query: 148 IIHRDLKSPNVLVADNLVAKVSDFGTSREWDNESAVMSFTG--TVAWMAPEVIRHEPCSE 321
IHRDL + NVLV +NL +K++DFG SR E V G V WMA E + + +
Sbjct: 975 FIHRDLAARNVLVGENLASKIADFGLSR--GEEVYVKKTMGRLPVRWMAIESLNYSVYTT 1032
Query: 322 RVDVWSFGVVLWELLT 369
+ DVWSFGV+LWE+++
Sbjct: 1033 KSDVWSFGVLLWEIVS 1048
>X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein.
Length = 348
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 153 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 212
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 213 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 272
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 273 VTYGRIPYPGMSNPEVI 289
>M16592-1|AAA52644.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 310 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 369
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 370 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 429
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 430 VTYGRIPYPGMSNPEVI 446
>M16591-1|AAA52643.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 310 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 369
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 370 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 429
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 430 VTYGRIPYPGMSNPEVI 446
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 97 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 155
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 156 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 215
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 216 EPPHSELHPMKVLF 229
>BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 331 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 390
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 391 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 450
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 451 VTYGRIPYPGMSNPEVI 467
>BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 331 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 390
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 391 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 450
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 451 VTYGRIPYPGMSNPEVI 467
>BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 331 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 390
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 391 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 450
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 451 VTYGRIPYPGMSNPEVI 467
>BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 331 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 390
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 391 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 450
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 451 VTYGRIPYPGMSNPEVI 467
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 97 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 155
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 156 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 215
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 216 EPPHSELHPMKVLF 229
>BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 92.3 bits (219), Expect = 7e-19
Identities = 56/136 (41%), Positives = 77/136 (56%), Gaps = 18/136 (13%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL---------------HSGAS-FTPRQIIRWAKDIAQGMVYLHNRK 147
I +E+ YG L DFL H AS + RQ++R+A D A GM YL ++
Sbjct: 915 IAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQ 974
Query: 148 IIHRDLKSPNVLVADNLVAKVSDFGTSREWDNESAVMSFTG--TVAWMAPEVIRHEPCSE 321
IHRDL + NVLV +NL +K++DFG SR E V G V WMA E + + +
Sbjct: 975 FIHRDLAARNVLVGENLASKIADFGLSR--GEEVYVKKTMGRLPVRWMAIESLNYSVYTT 1032
Query: 322 RVDVWSFGVVLWELLT 369
+ DVWSFGV+LWE+++
Sbjct: 1033 KSDVWSFGVLLWEIVS 1048
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 97 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 155
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 156 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 215
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 216 EPPHSELHPMKVLF 229
>BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 331 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 390
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 391 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 450
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 451 VTYGRIPYPGMSNPEVI 467
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 97 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 155
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 156 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 215
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 216 EPPHSELHPMKVLF 229
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 109 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 167
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 168 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 227
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 228 EPPHSELHPMKVLF 241
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 14 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 72
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 73 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 132
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 133 EPPHSELHPMKVLF 146
>AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 310 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 369
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 370 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 429
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 430 VTYGRIPYPGMSNPEVI 446
>AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 309 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 368
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 369 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 428
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 429 VTYGRIPYPGMSNPEVI 445
>AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 92.3 bits (219), Expect = 7e-19
Identities = 56/136 (41%), Positives = 77/136 (56%), Gaps = 18/136 (13%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL---------------HSGAS-FTPRQIIRWAKDIAQGMVYLHNRK 147
I +E+ YG L DFL H AS + RQ++R+A D A GM YL ++
Sbjct: 915 IAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQ 974
Query: 148 IIHRDLKSPNVLVADNLVAKVSDFGTSREWDNESAVMSFTG--TVAWMAPEVIRHEPCSE 321
IHRDL + NVLV +NL +K++DFG SR E V G V WMA E + + +
Sbjct: 975 FIHRDLAARNVLVGENLASKIADFGLSR--GEEVYVKKTMGRLPVRWMAIESLNYSVYTT 1032
Query: 322 RVDVWSFGVVLWELLT 369
+ DVWSFGV+LWE+++
Sbjct: 1033 KSDVWSFGVLLWEIVS 1048
>AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 541
Score = 92.3 bits (219), Expect = 7e-19
Identities = 56/136 (41%), Positives = 77/136 (56%), Gaps = 18/136 (13%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL---------------HSGAS-FTPRQIIRWAKDIAQGMVYLHNRK 147
I +E+ YG L DFL H AS + RQ++R+A D A GM YL ++
Sbjct: 318 IAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQ 377
Query: 148 IIHRDLKSPNVLVADNLVAKVSDFGTSREWDNESAVMSFTG--TVAWMAPEVIRHEPCSE 321
IHRDL + NVLV +NL +K++DFG SR E V G V WMA E + + +
Sbjct: 378 FIHRDLAARNVLVGENLASKIADFGLSR--GEEVYVKKTMGRLPVRWMAIESLNYSVYTT 435
Query: 322 RVDVWSFGVVLWELLT 369
+ DVWSFGV+LWE+++
Sbjct: 436 KSDVWSFGVLLWEIVS 451
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 97 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 155
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 156 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 215
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 216 EPPHSELHPMKVLF 229
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 109 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 167
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 168 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 227
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 228 EPPHSELHPMKVLF 241
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 14 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 72
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 73 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 132
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 133 EPPHSELHPMKVLF 146
>AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 310 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 369
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 370 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 429
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 430 VTYGRIPYPGMSNPEVI 446
>AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 309 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 368
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 369 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 428
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 429 VTYGRIPYPGMSNPEVI 445
>AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22779 fis, clone KAIA1741. ).
Length = 505
Score = 92.3 bits (219), Expect = 7e-19
Identities = 53/137 (38%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II EF G L DFL S G+ ++I ++ IA+GM ++ R IHRDL++ N+LV+
Sbjct: 310 IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS 369
Query: 190 DNLVAKVSDFGTSRE-WDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+LV K++DFG +R DNE +A + W APE I + + DVWSFG++L E+
Sbjct: 370 ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 429
Query: 364 LTQ-EIPYKTLETHAIL 411
+T IPY + ++
Sbjct: 430 VTYGRIPYPGMSNPEVI 446
>AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein.
Length = 421
Score = 92.3 bits (219), Expect = 7e-19
Identities = 56/136 (41%), Positives = 77/136 (56%), Gaps = 18/136 (13%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL---------------HSGAS-FTPRQIIRWAKDIAQGMVYLHNRK 147
I +E+ YG L DFL H AS + RQ++R+A D A GM YL ++
Sbjct: 198 IAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQ 257
Query: 148 IIHRDLKSPNVLVADNLVAKVSDFGTSREWDNESAVMSFTG--TVAWMAPEVIRHEPCSE 321
IHRDL + NVLV +NL +K++DFG SR E V G V WMA E + + +
Sbjct: 258 FIHRDLAARNVLVGENLASKIADFGLSR--GEEVYVKKTMGRLPVRWMAIESLNYSVYTT 315
Query: 322 RVDVWSFGVVLWELLT 369
+ DVWSFGV+LWE+++
Sbjct: 316 KSDVWSFGVLLWEIVS 331
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 109 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 167
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 168 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 227
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 228 EPPHSELHPMKVLF 241
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 92.3 bits (219), Expect = 7e-19
Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 1/134 (0%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
IIME+ G D L G QI ++I +G+ YLH+ K IHRD+K+ NVL++++
Sbjct: 97 IIMEYLGGGSALDLLEPGP-LDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEH 155
Query: 196 LVAKVSDFGTSRE-WDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ 372
K++DFG + + D + +F GT WMAPEVI+ + D+WS G+ EL
Sbjct: 156 GEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARG 215
Query: 373 EIPYKTLETHAILW 414
E P+ L +L+
Sbjct: 216 EPPHSELHPMKVLF 229
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 154 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 213
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 214 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 273
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 274 TTKGRVPYPGMVNREVL 290
>U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein.
Length = 626
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
I ME+ G + D L + + T ++ + I +GM YLH+ I+HRD+K N+L
Sbjct: 441 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500
Query: 196 LVAKVSDFGTSREWD----NESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
K+ DFG S+ + + + S TGT WM+PEVI E + DVWS G + E+
Sbjct: 501 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM 560
Query: 364 LTQEIPYKTLETHAILWGVGTE 429
LT++ P+ E A ++ + T+
Sbjct: 561 LTEKPPWAEYEAMAAIFKIATQ 582
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 91.9 bits (218), Expect = 9e-19
Identities = 53/131 (40%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E ++G L ++L + G+ Q + A +A GM YL +R IHRDL + NVLV
Sbjct: 304 IITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVG 363
Query: 190 DNLVAKVSDFGTSREW--DNESAVMS---FTGTVAWMAPEVIRHEPCSERVDVWSFGVVL 354
++ + KV+DFG +R + DNE S V W APE IR S + DVWSFG++L
Sbjct: 364 EHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILL 423
Query: 355 WELLTQ-EIPY 384
+E++T ++PY
Sbjct: 424 YEIITYGKMPY 434
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 91.9 bits (218), Expect = 9e-19
Identities = 53/131 (40%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E ++G L ++L + G+ Q + A +A GM YL +R IHRDL + NVLV
Sbjct: 304 IITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVG 363
Query: 190 DNLVAKVSDFGTSREW--DNESAVMS---FTGTVAWMAPEVIRHEPCSERVDVWSFGVVL 354
++ + KV+DFG +R + DNE S V W APE IR S + DVWSFG++L
Sbjct: 364 EHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILL 423
Query: 355 WELLTQ-EIPY 384
+E++T ++PY
Sbjct: 424 YEIITYGKMPY 434
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 339 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 398
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 399 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 458
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 459 TTKGRVPYPGMVNREVL 475
>DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 variant 2 protein.
Length = 622
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
I ME+ G + D L + + T ++ + I +GM YLH+ I+HRD+K N+L
Sbjct: 437 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 496
Query: 196 LVAKVSDFGTSREWD----NESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
K+ DFG S+ + + + S TGT WM+PEVI E + DVWS G + E+
Sbjct: 497 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM 556
Query: 364 LTQEIPYKTLETHAILWGVGTE 429
LT++ P+ E A ++ + T+
Sbjct: 557 LTEKPPWAEYEAMAAIFKIATQ 578
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASSTQDTGKL--PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 381
Query: 370 -QEIPY 384
+PY
Sbjct: 382 FGRVPY 387
>BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
I ME+ G + D L + + T ++ + I +GM YLH+ I+HRD+K N+L
Sbjct: 441 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500
Query: 196 LVAKVSDFGTSREWD----NESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
K+ DFG S+ + + + S TGT WM+PEVI E + DVWS G + E+
Sbjct: 501 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM 560
Query: 364 LTQEIPYKTLETHAILWGVGTE 429
LT++ P+ E A ++ + T+
Sbjct: 561 LTEKPPWAEYEAMAAIFKIATQ 582
>BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
I ME+ G + D L + + T ++ + I +GM YLH+ I+HRD+K N+L
Sbjct: 441 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500
Query: 196 LVAKVSDFGTSREWD----NESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
K+ DFG S+ + + + S TGT WM+PEVI E + DVWS G + E+
Sbjct: 501 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM 560
Query: 364 LTQEIPYKTLETHAILWGVGTE 429
LT++ P+ E A ++ + T+
Sbjct: 561 LTEKPPWAEYEAMAAIFKIATQ 582
>BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 protein.
Length = 626
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
I ME+ G + D L + + T ++ + I +GM YLH+ I+HRD+K N+L
Sbjct: 441 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500
Query: 196 LVAKVSDFGTSREWD----NESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
K+ DFG S+ + + + S TGT WM+PEVI E + DVWS G + E+
Sbjct: 501 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM 560
Query: 364 LTQEIPYKTLETHAILWGVGTE 429
LT++ P+ E A ++ + T+
Sbjct: 561 LTEKPPWAEYEAMAAIFKIATQ 582
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 339 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 398
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 399 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 458
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 459 TTKGRVPYPGMVNREVL 475
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 91.9 bits (218), Expect = 9e-19
Identities = 53/131 (40%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E ++G L ++L + G+ Q + A +A GM YL +R IHRDL + NVLV
Sbjct: 304 IITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVG 363
Query: 190 DNLVAKVSDFGTSREW--DNESAVMS---FTGTVAWMAPEVIRHEPCSERVDVWSFGVVL 354
++ + KV+DFG +R + DNE S V W APE IR S + DVWSFG++L
Sbjct: 364 EHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILL 423
Query: 355 WELLTQ-EIPY 384
+E++T ++PY
Sbjct: 424 YEIITYGKMPY 434
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 339 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 398
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 399 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 458
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 459 TTKGRVPYPGMVNREVL 475
>BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for
IMAGE:3506235) protein.
Length = 594
Score = 91.9 bits (218), Expect = 9e-19
Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADN 195
I ME+ G + D L + + T ++ + I +GM YLH+ I+HRD+K N+L
Sbjct: 409 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 468
Query: 196 LVAKVSDFGTSREWD----NESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
K+ DFG S+ + + + S TGT WM+PEVI E + DVWS G + E+
Sbjct: 469 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM 528
Query: 364 LTQEIPYKTLETHAILWGVGTE 429
LT++ P+ E A ++ + T+
Sbjct: 529 LTEKPPWAEYEAMAAIFKIATQ 550
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 91.9 bits (218), Expect = 9e-19
Identities = 53/131 (40%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E ++G L ++L + G+ Q + A +A GM YL +R IHRDL + NVLV
Sbjct: 304 IITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVG 363
Query: 190 DNLVAKVSDFGTSREW--DNESAVMS---FTGTVAWMAPEVIRHEPCSERVDVWSFGVVL 354
++ + KV+DFG +R + DNE S V W APE IR S + DVWSFG++L
Sbjct: 364 EHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILL 423
Query: 355 WELLTQ-EIPY 384
+E++T ++PY
Sbjct: 424 YEIITYGKMPY 434
>AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 339 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 398
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 399 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 458
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 459 TTKGRVPYPGMVNREVL 475
>AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 345 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 404
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 405 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 464
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 465 TTKGRVPYPGMVNREVL 481
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 91.9 bits (218), Expect = 9e-19
Identities = 53/131 (40%), Positives = 77/131 (58%), Gaps = 8/131 (6%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
II E ++G L ++L + G+ Q + A +A GM YL +R IHRDL + NVLV
Sbjct: 304 IITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVG 363
Query: 190 DNLVAKVSDFGTSREW--DNESAVMS---FTGTVAWMAPEVIRHEPCSERVDVWSFGVVL 354
++ + KV+DFG +R + DNE S V W APE IR S + DVWSFG++L
Sbjct: 364 EHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILL 423
Query: 355 WELLTQ-EIPY 384
+E++T ++PY
Sbjct: 424 YEIITYGKMPY 434
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, the
PTK6 gene for ).).
Length = 488
Score = 91.9 bits (218), Expect = 9e-19
Identities = 54/142 (38%), Positives = 79/142 (55%), Gaps = 5/142 (3%)
Frame = +1
Query: 1 GENYCIIMEFCQYGPLYDFLHS--GASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSP 174
GE I+ E + G L FL + G + ++ +A +A+GM YL ++++HRDL +
Sbjct: 295 GEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAAR 354
Query: 175 NVLVADNLVAKVSDFGTSR--EWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGV 348
NVLV D L KV+DFG +R + D S S V W APE + S++ DVWSFGV
Sbjct: 355 NVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGV 414
Query: 349 VLWELLTQ-EIPYKTLETHAIL 411
+L E+ T + PY+ + H L
Sbjct: 415 LLHEVFTYGQCPYEGMTNHETL 436
>AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens
cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to
Rattus norvegicus tyrosine protein kinase pp60-c-src
mRNA. ).
Length = 251
Score = 91.9 bits (218), Expect = 9e-19
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFL--HSGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L DFL +G Q++ A IA GM Y+ +HRDL++ N+LV
Sbjct: 54 IVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVG 113
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV KV+DFG +R DNE +A + W APE + + + DVWSFG++L EL
Sbjct: 114 ENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 173
Query: 364 LTQ-EIPYKTLETHAIL 411
T+ +PY + +L
Sbjct: 174 TTKGRVPYPGMVNREVL 190
>M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1
mRNA. ).
Length = 543
Score = 91.5 bits (217), Expect = 1e-18
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPR--QIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ EF G L DFL G + Q++ A IA GM Y+ IHRDL++ N+LV
Sbjct: 346 IVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVG 405
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV K++DFG +R DNE +A + W APE + + + DVWSFG++ EL
Sbjct: 406 ENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTEL 465
Query: 364 LTQ-EIPYKTLETHAIL 411
+T+ +PY + +L
Sbjct: 466 VTKGRVPYPGMVNREVL 482
>BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral oncogene homolog 1 protein.
Length = 543
Score = 91.5 bits (217), Expect = 1e-18
Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGASFTPR--QIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ EF G L DFL G + Q++ A IA GM Y+ IHRDL++ N+LV
Sbjct: 346 IVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVG 405
Query: 190 DNLVAKVSDFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWEL 363
+NLV K++DFG +R DNE +A + W APE + + + DVWSFG++ EL
Sbjct: 406 ENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTEL 465
Query: 364 LTQ-EIPYKTLETHAIL 411
+T+ +PY + +L
Sbjct: 466 VTKGRVPYPGMVNREVL 482
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 91.5 bits (217), Expect = 1e-18
Identities = 48/126 (38%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHS-GASFTPRQ-IIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVA 189
I+ E+ G L D+L S G S +++++ D+ + M YL +HRDL + NVLV+
Sbjct: 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query: 190 DNLVAKVSDFGTSREWDNESAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLT 369
++ VAKVSDFG ++E + V W APE +R + S + DVWSFG++LWE+ +
Sbjct: 324 EDNVAKVSDFGLTKEASTQDTGKL---PVKWTAPEALREKKFSTKSDVWSFGILLWEIYS 380
Query: 370 -QEIPY 384
+PY
Sbjct: 381 FGRVPY 386
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 91.1 bits (216), Expect = 2e-18
Identities = 51/129 (39%), Positives = 72/129 (55%), Gaps = 6/129 (4%)
Frame = +1
Query: 16 IIMEFCQYGPLYDFLHSGAS-FTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVAD 192
IIME G FL +Q+++++ D A GM+YL ++ IHRDL + N LV +
Sbjct: 635 IIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGE 694
Query: 193 NLVAKVSDFGTSREWDNESAVMSFTG----TVAWMAPEVIRHEPCSERVDVWSFGVVLWE 360
N V K+SDFG SR+ D V S +G + W APE + + S DVWSFG++LWE
Sbjct: 695 NNVLKISDFGMSRQED--GGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWE 752
Query: 361 LLTQEI-PY 384
+ + PY
Sbjct: 753 TFSLGVCPY 761
>BC008655-1|AAH08655.1| 253|Homo sapiens EPHA2 protein protein.
Length = 253
Score = 91.1 bits (216), Expect = 2e-18
Identities = 48/104 (46%), Positives = 62/104 (59%), Gaps = 5/104 (4%)
Frame = +1
Query: 115 AQGMVYLHNRKIIHRDLKSPNVLVADNLVAKVSDFGTSR--EWDNESAVMSFTG--TVAW 282
A GM YL N +HRDL + N+LV NLV KVSDFG SR E D E+ + G + W
Sbjct: 1 AAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRW 60
Query: 283 MAPEVIRHEPCSERVDVWSFGVVLWELLTQ-EIPYKTLETHAIL 411
APE I + + DVWSFG+V+WE++T E PY L H ++
Sbjct: 61 TAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVM 104
>BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein.
Length = 539
Score = 90.6 bits (215), Expect = 2e-18
Identities = 50/120 (41%), Positives = 72/120 (60%), Gaps = 5/120 (4%)
Frame = +1
Query: 40 GPLYDFLH--SGASFTPRQIIRWAKDIAQGMVYLHNRKIIHRDLKSPNVLVADNLVAKVS 213
G L DFL SG T +++ A IA+GM ++ R IHRDL++ N+LV+D L K++
Sbjct: 352 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIA 411
Query: 214 DFGTSR-EWDNE-SAVMSFTGTVAWMAPEVIRHEPCSERVDVWSFGVVLWELLTQ-EIPY 384
DFG +R DNE +A + W APE I + + + DVWSFG++L E++T IPY
Sbjct: 412 DFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 471
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,986,574
Number of Sequences: 237096
Number of extensions: 1916544
Number of successful extensions: 10005
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6911
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7447
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3659526016
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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