Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-1181
(345 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4325 Cluster: PREDICTED: similar to aconitase,... 204 2e-52
UniRef50_Q99798 Cluster: Aconitate hydratase, mitochondrial prec... 197 4e-50
UniRef50_O13966 Cluster: Aconitate hydratase, mitochondrial prec... 194 4e-49
UniRef50_Q9VIE8 Cluster: CG9244-PB; n=37; cellular organisms|Rep... 192 1e-48
UniRef50_Q0CSK9 Cluster: Aconitate hydratase, mitochondrial; n=2... 187 5e-47
UniRef50_P19414 Cluster: Aconitate hydratase, mitochondrial prec... 181 3e-45
UniRef50_Q0USA6 Cluster: Putative uncharacterized protein; n=2; ... 161 3e-39
UniRef50_Q4PB22 Cluster: Putative uncharacterized protein; n=5; ... 157 4e-38
UniRef50_Q2UTF0 Cluster: Aconitase/homoaconitase; n=9; cellular ... 154 3e-37
UniRef50_A0RTP9 Cluster: 3-isopropylmalate isomerase/aconitase A... 153 8e-37
UniRef50_O75944 Cluster: Aconitase; n=34; cellular organisms|Rep... 120 7e-27
UniRef50_Q7NDZ5 Cluster: Aconitate hydratase; n=28; Bacteria|Rep... 102 2e-21
UniRef50_O67656 Cluster: Aconitase; n=17; cellular organisms|Rep... 99 1e-20
UniRef50_Q74AD1 Cluster: Aconitate hydratase, putative; n=12; Ba... 98 3e-20
UniRef50_Q5V0F1 Cluster: Aconitate hydratase; n=8; cellular orga... 88 4e-17
UniRef50_Q5K9V9 Cluster: Homoaconitase, mitochondrial precursor;... 68 5e-11
UniRef50_A2SQ03 Cluster: 3-isopropylmalate dehydratase; n=5; Met... 64 8e-10
UniRef50_Q4J9H0 Cluster: Aconitate hydratase; n=7; cellular orga... 61 6e-09
UniRef50_Q9WYC7 Cluster: 3-isopropylmalate dehydratase large sub... 60 8e-09
UniRef50_Q4WUL6 Cluster: Homoaconitase, mitochondrial precursor;... 60 1e-08
UniRef50_A4M821 Cluster: Homoaconitate hydratase family protein;... 58 3e-08
UniRef50_Q97Z42 Cluster: Aconitate hydratase; n=3; cellular orga... 58 3e-08
UniRef50_Q58409 Cluster: 3-isopropylmalate dehydratase large sub... 58 3e-08
UniRef50_Q1IMD4 Cluster: Aconitate hydratase-like; n=1; Acidobac... 57 7e-08
UniRef50_Q2GN26 Cluster: Homoaconitase, mitochondrial precursor;... 57 7e-08
UniRef50_A5ZNE1 Cluster: Putative uncharacterized protein; n=1; ... 57 9e-08
UniRef50_Q5PXM8 Cluster: Aconitase A; n=3; Gammaproteobacteria|R... 56 1e-07
UniRef50_P75764 Cluster: Uncharacterized protein ybhJ; n=32; Bac... 56 1e-07
UniRef50_P81291 Cluster: 3-isopropylmalate dehydratase large sub... 56 1e-07
UniRef50_Q0W1Q4 Cluster: 3-isopropylmalate dehydratase, large su... 55 4e-07
UniRef50_Q125M5 Cluster: Aconitate hydratase-like; n=8; Proteoba... 54 5e-07
UniRef50_Q9RNH9 Cluster: Aconitase; n=3; Bacteria|Rep: Aconitase... 54 7e-07
UniRef50_Q9RTY9 Cluster: 3-isopropylmalate dehydratase large sub... 54 7e-07
UniRef50_A5ZND9 Cluster: Putative uncharacterized protein; n=1; ... 54 9e-07
UniRef50_P49367 Cluster: Homoaconitase, mitochondrial precursor;... 53 1e-06
UniRef50_Q42560 Cluster: Aconitate hydratase 1; n=35; cellular o... 53 2e-06
UniRef50_UPI00015BAFD3 Cluster: 3-isopropylmalate dehydratase; n... 52 2e-06
UniRef50_A0HK99 Cluster: Aconitate hydratase-like; n=3; Burkhold... 52 2e-06
UniRef50_A3BB05 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-06
UniRef50_Q97VY2 Cluster: 3-isopropylmalate dehydratase large sub... 52 2e-06
UniRef50_Q9I3F5 Cluster: Aconitate hydratase 1; n=98; Bacteria|R... 52 2e-06
UniRef50_Q8TVF2 Cluster: 3-isopropylmalate dehydratase large sub... 51 5e-06
UniRef50_Q6NH63 Cluster: Aconitate hydratase; n=32; cellular org... 51 5e-06
UniRef50_A6G875 Cluster: 3-isopropylmalate dehydratase; n=1; Ple... 50 8e-06
UniRef50_Q0ZQ48 Cluster: FrbA; n=6; cellular organisms|Rep: FrbA... 50 1e-05
UniRef50_A5C294 Cluster: Putative uncharacterized protein; n=1; ... 50 1e-05
UniRef50_A7DAM6 Cluster: Aconitate hydratase domain protein; n=1... 49 2e-05
UniRef50_A6NVP4 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-05
UniRef50_O67078 Cluster: 3-isopropylmalate dehydratase large sub... 49 2e-05
UniRef50_Q4T087 Cluster: Chromosome undetermined SCAF11289, whol... 48 4e-05
UniRef50_A5WEQ7 Cluster: 2-methylisocitrate dehydratase, Fe/S-de... 48 4e-05
UniRef50_Q5V7D3 Cluster: Aconitate hydratase I; n=4; cellular or... 48 6e-05
UniRef50_P21399 Cluster: Iron-responsive element-binding protein... 48 6e-05
UniRef50_Q8NQ98 Cluster: Aconitate hydratase; n=10; Bacteria|Rep... 47 1e-04
UniRef50_Q7N5S3 Cluster: Similar to large subunit of 3-isopropyl... 46 2e-04
UniRef50_A7NXJ3 Cluster: Chromosome chr5 scaffold_2, whole genom... 46 2e-04
UniRef50_Q9RTI6 Cluster: 3-isopropylmalate dehydratase large sub... 45 3e-04
UniRef50_Q0ADB7 Cluster: Aconitate hydratase 1; n=5; Bacteria|Re... 44 5e-04
UniRef50_A6DRT0 Cluster: 3-isopropylmalate dehydratase; n=4; Bac... 44 5e-04
UniRef50_A0ZF76 Cluster: 3-isopropylmalate dehydratase, LeuC sub... 44 5e-04
UniRef50_Q7WB80 Cluster: Aconitate hydratase; n=3; Bordetella|Re... 44 7e-04
UniRef50_Q8TW29 Cluster: 3-isopropylmalate dehydratase large sub... 44 7e-04
UniRef50_A1W553 Cluster: Aconitate hydratase 1 precursor; n=8; P... 44 0.001
UniRef50_Q89X98 Cluster: 3-isopropylmalate dehydratase large sub... 44 0.001
UniRef50_Q8KER8 Cluster: 3-isopropylmalate dehydratase, large su... 43 0.001
UniRef50_Q1LAU9 Cluster: Homoaconitate hydratase family protein;... 43 0.002
UniRef50_Q0C395 Cluster: Putative 3-isopropylmalate dehydratase,... 42 0.002
UniRef50_Q5P0Q2 Cluster: Aconitase; n=4; Proteobacteria|Rep: Aco... 42 0.003
UniRef50_Q1AVC5 Cluster: Homoaconitate hydratase family protein;... 42 0.004
UniRef50_Q6L0K5 Cluster: 3-isopropylmalate dehydratase large sub... 42 0.004
UniRef50_Q8PUG1 Cluster: 3-isopropylmalate dehydratase large sub... 41 0.006
UniRef50_A4FHT3 Cluster: Aconitate hydratase 1; n=2; Actinomycet... 40 0.009
UniRef50_Q2GXH4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.009
UniRef50_P07264 Cluster: 3-isopropylmalate dehydratase; n=473; c... 40 0.009
UniRef50_P48200 Cluster: Iron-responsive element-binding protein... 40 0.011
UniRef50_A0RXN9 Cluster: 3-isopropylmalate dehydratase large sub... 40 0.015
UniRef50_Q5FUG3 Cluster: 3-isopropylmalate dehydratase large sub... 40 0.015
UniRef50_Q65VS0 Cluster: 3-isopropylmalate dehydratase large sub... 40 0.015
UniRef50_Q8U0C0 Cluster: 3-isopropylmalate dehydratase large sub... 39 0.020
UniRef50_A7CSQ0 Cluster: Aconitate hydratase 1; n=1; Opitutaceae... 39 0.026
UniRef50_Q4WBR0 Cluster: Aconitase family protein; n=7; Pezizomy... 39 0.026
UniRef50_UPI00006D922D Cluster: COG0065: 3-isopropylmalate dehyd... 38 0.035
UniRef50_Q74BX5 Cluster: 3-isopropylmalate dehydratase, large su... 38 0.035
UniRef50_Q4VDG4 Cluster: Putative 3-isopropylmalate dehydratase ... 38 0.035
UniRef50_Q59938 Cluster: Aconitate hydratase; n=356; cellular or... 38 0.035
UniRef50_A3LRP7 Cluster: 3-isopropylmalate dehydratase; n=1; Pic... 38 0.060
UniRef50_O08451 Cluster: Aconitate hydratase; n=21; Bacteria|Rep... 37 0.080
UniRef50_Q08N42 Cluster: Aconitate hydratase; n=2; Cystobacterin... 37 0.11
UniRef50_Q82WI9 Cluster: 3-isopropylmalate dehydratase large sub... 36 0.14
UniRef50_A5WGT5 Cluster: 3-isopropylmalate dehydratase, large su... 35 0.32
UniRef50_O53237 Cluster: 3-isopropylmalate dehydratase large sub... 35 0.32
UniRef50_A7H0L8 Cluster: 3-isopropylmalate dehydratase, large su... 33 0.98
UniRef50_Q18GT3 Cluster: 3-isopropylmalate dehydratase large sub... 33 0.98
UniRef50_Q05FR0 Cluster: 3-isopropylmalate dehydratase large sub... 33 1.3
UniRef50_Q7WPW8 Cluster: Aconitase family protein; n=2; Bordetel... 32 3.0
UniRef50_A5WFV6 Cluster: Putative uncharacterized protein; n=1; ... 31 4.0
UniRef50_A2Q8B9 Cluster: Contig An01c0120, complete genome; n=5;... 31 4.0
UniRef50_A5AFK5 Cluster: Putative uncharacterized protein; n=2; ... 31 5.3
UniRef50_A2QCU4 Cluster: Similarity to hypothetical DNA-binding ... 31 5.3
UniRef50_Q6KZ03 Cluster: 3-isopropylmalate dehydratase large sub... 31 5.3
UniRef50_UPI0000DD8049 Cluster: PREDICTED: similar to amyloid be... 31 6.9
UniRef50_Q57WV6 Cluster: Putative uncharacterized protein; n=1; ... 31 6.9
UniRef50_Q49GP5 Cluster: Phosphatidylinositol 4-kinase type 2-be... 31 6.9
UniRef50_A1HNW5 Cluster: Benzoate transporter; n=2; Clostridiale... 30 9.2
UniRef50_P53656 Cluster: Adenosylmethionine-8-amino-7-oxononanoa... 30 9.2
>UniRef50_UPI00015B4325 Cluster: PREDICTED: similar to aconitase,
mitochondrial; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aconitase, mitochondrial - Nasonia
vitripennis
Length = 917
Score = 204 bits (499), Expect = 2e-52
Identities = 95/114 (83%), Positives = 98/114 (85%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
KEVY FL+TAGAKYGVGFW PGSGIIHQIILENYAFPGLLMIGTDSHTPN
Sbjct: 282 KEVYSFLKTAGAKYGVGFWNPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIG 341
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVDVMANIPWELKCPKVIGVKLTG+L GWTSPKD+ILKVAGILTVKGGT
Sbjct: 342 VGGADAVDVMANIPWELKCPKVIGVKLTGELKGWTSPKDIILKVAGILTVKGGT 395
>UniRef50_Q99798 Cluster: Aconitate hydratase, mitochondrial
precursor; n=28; cellular organisms|Rep: Aconitate
hydratase, mitochondrial precursor - Homo sapiens
(Human)
Length = 780
Score = 197 bits (481), Expect = 4e-50
Identities = 91/114 (79%), Positives = 97/114 (85%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
+EVY FL TAGAKYGVGFWKPGSGIIHQIILENYA+PG+L+IGTDSHTPN
Sbjct: 148 QEVYNFLATAGAKYGVGFWKPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIG 207
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVDVMA IPWELKCPKVIGVKLTG L+GW+SPKDVILKVAGILTVKGGT
Sbjct: 208 VGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGT 261
>UniRef50_O13966 Cluster: Aconitate hydratase, mitochondrial
precursor; n=21; cellular organisms|Rep: Aconitate
hydratase, mitochondrial precursor - Schizosaccharomyces
pombe (Fission yeast)
Length = 778
Score = 194 bits (472), Expect = 4e-49
Identities = 89/114 (78%), Positives = 96/114 (84%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
KEVY FL+TA AKY +GFW+PGSGIIHQI+LENYAFPG L+IGTDSHTPN
Sbjct: 144 KEVYDFLQTACAKYNIGFWRPGSGIIHQIVLENYAFPGGLLIGTDSHTPNAGGLGMVAIG 203
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVDVMAN+PWELKCPKVIGVKLTG+L GWTSPKDVILKVAGILTVKGGT
Sbjct: 204 VGGADAVDVMANLPWELKCPKVIGVKLTGQLKGWTSPKDVILKVAGILTVKGGT 257
>UniRef50_Q9VIE8 Cluster: CG9244-PB; n=37; cellular organisms|Rep:
CG9244-PB - Drosophila melanogaster (Fruit fly)
Length = 787
Score = 192 bits (469), Expect = 1e-48
Identities = 90/114 (78%), Positives = 95/114 (83%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
KEVY FL + AKYG+GFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPN
Sbjct: 155 KEVYDFLASTCAKYGLGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIG 214
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVDVMA+IPWELKCPKVIGV LTGK++GWTSPKDVILKVA ILTVKGGT
Sbjct: 215 VGGADAVDVMADIPWELKCPKVIGVNLTGKISGWTSPKDVILKVADILTVKGGT 268
>UniRef50_Q0CSK9 Cluster: Aconitate hydratase, mitochondrial; n=2;
Pezizomycotina|Rep: Aconitate hydratase, mitochondrial -
Aspergillus terreus (strain NIH 2624)
Length = 781
Score = 187 bits (455), Expect = 5e-47
Identities = 85/114 (74%), Positives = 94/114 (82%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
KEVY FL TA AKY +GFWKPGSGIIHQI+LENYAFPG LMIGTDSHTPN
Sbjct: 178 KEVYDFLATATAKYNIGFWKPGSGIIHQIVLENYAFPGGLMIGTDSHTPNAGGLAMAAIG 237
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVDVMA +PWELK PKVIGVKLTG+++GWT+PKD+ILKVAG+LTVKGGT
Sbjct: 238 VGGADAVDVMAGLPWELKAPKVIGVKLTGEMSGWTTPKDIILKVAGLLTVKGGT 291
>UniRef50_P19414 Cluster: Aconitate hydratase, mitochondrial
precursor; n=41; cellular organisms|Rep: Aconitate
hydratase, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 778
Score = 181 bits (440), Expect = 3e-45
Identities = 82/114 (71%), Positives = 91/114 (79%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
KEVY FL +A AKY +GFWKPGSGIIHQI+LENYAFPG L+IGTDSHTPN
Sbjct: 144 KEVYDFLASATAKYNMGFWKPGSGIIHQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIG 203
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVDVMA PWELK PK++GVKLTGK+ GWTSPKD+ILK+AGI TVKGGT
Sbjct: 204 VGGADAVDVMAGRPWELKAPKILGVKLTGKMNGWTSPKDIILKLAGITTVKGGT 257
>UniRef50_Q0USA6 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 781
Score = 161 bits (391), Expect = 3e-39
Identities = 70/114 (61%), Positives = 87/114 (76%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
KEV+ FLE+A KYG+ FW PG+GIIHQ +LENY+ PGL+M+GTDSH+PN
Sbjct: 164 KEVFDFLESAAKKYGIEFWPPGAGIIHQSVLENYSAPGLMMLGTDSHSPNAGGLGAIVIG 223
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVD + + PWELK PK++GVKLTG+L+GW SPKDVIL +AG LTV+GGT
Sbjct: 224 VGGADAVDALVDAPWELKAPKILGVKLTGELSGWASPKDVILSLAGQLTVRGGT 277
>UniRef50_Q4PB22 Cluster: Putative uncharacterized protein; n=5;
Fungi/Metazoa group|Rep: Putative uncharacterized
protein - Ustilago maydis (Smut fungus)
Length = 1041
Score = 157 bits (382), Expect = 4e-38
Identities = 72/114 (63%), Positives = 84/114 (73%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
+EV+ FLE+A KYG+ FW PGSGIIHQI+LENYA PGLLM+GTDSHTPN
Sbjct: 264 QEVFAFLESASKKYGIEFWGPGSGIIHQIVLENYAAPGLLMLGTDSHTPNASGLGCLAIG 323
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
ADAVD M N PWEL PKV+GV L G+L+ W +PKDVIL +AG LTV+GGT
Sbjct: 324 VGGADAVDAMTNTPWELMAPKVLGVHLKGELSPWCTPKDVILHLAGKLTVRGGT 377
>UniRef50_Q2UTF0 Cluster: Aconitase/homoaconitase; n=9; cellular
organisms|Rep: Aconitase/homoaconitase - Aspergillus
oryzae
Length = 806
Score = 154 bits (374), Expect = 3e-37
Identities = 67/112 (59%), Positives = 84/112 (75%)
Frame = +2
Query: 5 EVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXX 184
EVY+FL +A KYG+GFWKPGSGIIH +I EN+A PG L+IGTDSHTPN
Sbjct: 158 EVYEFLSSASRKYGIGFWKPGSGIIHTVIFENHAVPGGLIIGTDSHTPNAGGLAMMGIGV 217
Query: 185 XXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+DAVD M+ +PWEL P+++GV+LTG+L+GW S KD+I K+AGILTV GG
Sbjct: 218 GGSDAVDAMSGMPWELVTPQIVGVRLTGQLSGWASTKDIICKLAGILTVSGG 269
>UniRef50_A0RTP9 Cluster: 3-isopropylmalate isomerase/aconitase A;
n=7; cellular organisms|Rep: 3-isopropylmalate
isomerase/aconitase A - Cenarchaeum symbiosum
Length = 754
Score = 153 bits (371), Expect = 8e-37
Identities = 72/113 (63%), Positives = 82/113 (72%)
Frame = +2
Query: 5 EVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXX 184
EV++FL++A A+YG GFWKPG+GIIHQ++LENYAFPG LMIGTDSHTPN
Sbjct: 118 EVFRFLKSAAARYGCGFWKPGAGIIHQVVLENYAFPGGLMIGTDSHTPNAGGLGMIAVGV 177
Query: 185 XXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
DA + MA WEL PK IGV LTGK +GWTSPKDVILKV LTV GGT
Sbjct: 178 GGMDAAEAMAIKEWELLYPKRIGVHLTGKSSGWTSPKDVILKVVEELTVSGGT 230
>UniRef50_O75944 Cluster: Aconitase; n=34; cellular organisms|Rep:
Aconitase - Homo sapiens (Human)
Length = 600
Score = 120 bits (289), Expect = 7e-27
Identities = 57/82 (69%), Positives = 62/82 (75%)
Frame = +2
Query: 98 NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLT 277
NYA+PG+L+IGTDSHTPN D VDVMA IP ELKC KVI +KLTG L+
Sbjct: 1 NYAYPGVLLIGTDSHTPNGGGLGGISIGVGGRDRVDVMAGIPCELKCTKVIAMKLTGSLS 60
Query: 278 GWTSPKDVILKVAGILTVKGGT 343
GWTSPKDVILKVAGILTVKGGT
Sbjct: 61 GWTSPKDVILKVAGILTVKGGT 82
>UniRef50_Q7NDZ5 Cluster: Aconitate hydratase; n=28; Bacteria|Rep:
Aconitate hydratase - Gloeobacter violaceus
Length = 645
Score = 102 bits (244), Expect = 2e-21
Identities = 48/111 (43%), Positives = 67/111 (60%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXX 190
+++L++ G KYG+ F +PG+GI HQ+ E +A P ++G+DSHTP
Sbjct: 76 HRYLQSVGQKYGIVFSRPGNGICHQVHRERFAVPAQTLLGSDSHTPTCGGLGMLAIGAGG 135
Query: 191 ADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
D MA P+ + PKV+GV+LTG L W S KDVIL++ LTVKGGT
Sbjct: 136 LDVAVAMAGEPYFIPMPKVLGVRLTGTLQPWCSGKDVILEMLRRLTVKGGT 186
>UniRef50_O67656 Cluster: Aconitase; n=17; cellular organisms|Rep:
Aconitase - Aquifex aeolicus
Length = 659
Score = 99 bits (238), Expect = 1e-20
Identities = 46/110 (41%), Positives = 65/110 (59%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXX 190
+K+L + K+G+ KPG+GI HQ+ LE +A PG ++G+DSHTP
Sbjct: 79 HKYLMSVAKKFGIWLSKPGNGICHQVHLERFAKPGKTLLGSDSHTPTAGGMGMLAIGAGG 138
Query: 191 ADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
D MA P+ LK PK++GV L GK+ W + KD+IL++ LTVKGG
Sbjct: 139 LDVAAAMAGEPFYLKMPKIVGVHLKGKMPEWVTAKDIILELLRRLTVKGG 188
>UniRef50_Q74AD1 Cluster: Aconitate hydratase, putative; n=12;
Bacteria|Rep: Aconitate hydratase, putative - Geobacter
sulfurreducens
Length = 645
Score = 98.3 bits (234), Expect = 3e-20
Identities = 49/108 (45%), Positives = 62/108 (57%)
Frame = +2
Query: 17 FLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXAD 196
FL TA ++GV KPG+G+ HQ+ LE + PG M+G DSHT + D
Sbjct: 80 FLMTAAQRFGVHLSKPGNGVSHQVHLERFGVPGRTMLGADSHTTSAAGLSMIAIGAGGLD 139
Query: 197 AVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
MA P+ L CPK+ GVKLTG+L W S KDVIL++ TVKGG
Sbjct: 140 VSLAMAGHPFHLPCPKIWGVKLTGQLQPWVSAKDVILEMLRRHTVKGG 187
>UniRef50_Q5V0F1 Cluster: Aconitate hydratase; n=8; cellular
organisms|Rep: Aconitate hydratase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 677
Score = 87.8 bits (208), Expect = 4e-17
Identities = 41/110 (37%), Positives = 62/110 (56%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXX 190
++FL +A +G F +PG+GI H + EN+A PG M+G+DSHTP
Sbjct: 98 HRFLRSAAGTFGAHFSRPGNGICHNVHKENFAAPGKTMLGSDSHTPTPGGLGELAIGSGG 157
Query: 191 ADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
D M + ++ P+V+ V+L G+L W + KDVIL++ L+VKGG
Sbjct: 158 LDVAVAMGGGAYYIEMPEVVNVRLEGELPEWATAKDVILELLRRLSVKGG 207
>UniRef50_Q5K9V9 Cluster: Homoaconitase, mitochondrial precursor;
n=3; Dikarya|Rep: Homoaconitase, mitochondrial precursor
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 728
Score = 67.7 bits (158), Expect = 5e-11
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 1/105 (0%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
YK ++ ++GV F+ G GI HQII+E YA+PG +++ +DSH+ +
Sbjct: 110 YKKIQAFAKEHGVDFYPAGRGIGHQIIVEEGYAWPGKMVVASDSHSNHYGGVGCLGTAIV 169
Query: 188 XADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
DA + A + + P+++ V L G+L+ + KDVI+ +AG+
Sbjct: 170 RTDAAGIWATGKFWWQIPRIVSVSLDGRLSPGVTGKDVIVALAGL 214
>UniRef50_A2SQ03 Cluster: 3-isopropylmalate dehydratase; n=5;
Methanomicrobia|Rep: 3-isopropylmalate dehydratase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 417
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/100 (34%), Positives = 48/100 (48%)
Frame = +2
Query: 44 GVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIP 223
G+ F + G GI HQI+ E PG +++G DSH+ D + A
Sbjct: 87 GMHFHEVGCGICHQIMSEGVCLPGEIVVGADSHSCTLGALGAFSTGVGATDMAGIWATGG 146
Query: 224 WELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ P+ I + L+GKL+G T PKDV L L + GGT
Sbjct: 147 TWFRVPESISIVLSGKLSGHTEPKDVALSYVKALGMDGGT 186
>UniRef50_Q4J9H0 Cluster: Aconitate hydratase; n=7; cellular
organisms|Rep: Aconitate hydratase - Sulfolobus
acidocaldarius
Length = 848
Score = 60.9 bits (141), Expect = 6e-09
Identities = 43/125 (34%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Frame = +2
Query: 5 EVYKFLETAGAKY-GVGFWKPGSGIIHQIILENYA-------FPGLL------MIGTDSH 142
E YKFL+ A + + + PG GIIHQI LE + F G L +IGTDSH
Sbjct: 140 ERYKFLKWAQRSFKNLRVFPPGKGIIHQINLEYLSKVVDVKEFRGQLTAYPEIVIGTDSH 199
Query: 143 TPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
TP +A VM P+ + P+V+GV+L G++ +P D++L +
Sbjct: 200 TPMTNGLGVLSWGVGGLEAEAVMLGEPYTMAVPEVVGVRLVGEIKEGVTPTDIVLYITEK 259
Query: 323 LTVKG 337
L KG
Sbjct: 260 LRKKG 264
>UniRef50_Q9WYC7 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=8; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 1 -
Thermotoga maritima
Length = 418
Score = 60.5 bits (140), Expect = 8e-09
Identities = 37/110 (33%), Positives = 48/110 (43%)
Frame = +2
Query: 14 KFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXA 193
K + G + GV + G GI HQI+ E Y PG L+ G DSHT
Sbjct: 78 KMMREFGKEMGVKVFDAGDGISHQILAEKYVKPGDLVAGADSHTCTAGGLGAFGTGMGST 137
Query: 194 DAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
D + K P+ I V + GKL KD+IL++A IL G T
Sbjct: 138 DVAIIFGLGQNWFKVPETIKVVVNGKLQDGVYAKDIILEIARILGSDGAT 187
>UniRef50_Q4WUL6 Cluster: Homoaconitase, mitochondrial precursor;
n=10; Pezizomycotina|Rep: Homoaconitase, mitochondrial
precursor - Aspergillus fumigatus (Sartorya fumigata)
Length = 777
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
Y+ +E ++G+ F+ G G+ HQI++E YAFPG + + +DSH+
Sbjct: 157 YESIEKFAKQHGIDFYPAGHGVGHQIMIEEGYAFPGTVTVASDSHSNMYGGVGCLGTPMV 216
Query: 188 XADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
DA + A K P + V+ TG L + KDVI+ ++G+
Sbjct: 217 RTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTGKDVIVALSGL 261
>UniRef50_A4M821 Cluster: Homoaconitate hydratase family protein;
n=5; Bacteria|Rep: Homoaconitate hydratase family
protein - Petrotoga mobilis SJ95
Length = 419
Score = 58.4 bits (135), Expect = 3e-08
Identities = 36/113 (31%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
Frame = +2
Query: 8 VYKFLETAGAKYGVGFWKPGSGIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXX 184
++K + + YG F+ G GI HQ++ E +A PG ++IG DSHT
Sbjct: 79 LHKLMRDFSSNYGTKFYDIGEGICHQLMPEKGHALPGQIVIGADSHTCTYGALNCFSTGV 138
Query: 185 XXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
D MA+ K P+ I + L G L+ KDV L V +T G T
Sbjct: 139 GSTDLAIAMASGKLWFKVPQSIKIVLEGSLSKGIYSKDVALYVIKNMTANGAT 191
>UniRef50_Q97Z42 Cluster: Aconitate hydratase; n=3; cellular
organisms|Rep: Aconitate hydratase - Sulfolobus
solfataricus
Length = 855
Score = 58.4 bits (135), Expect = 3e-08
Identities = 44/124 (35%), Positives = 61/124 (49%), Gaps = 14/124 (11%)
Frame = +2
Query: 5 EVYKFLETA-GAKYGVGFWKPGSGIIHQIILENYA-------FPGLL------MIGTDSH 142
E Y+FL+ A GA + PG GIIHQ+ LE + GLL +IGTDSH
Sbjct: 143 ERYQFLKWAQGAFRNLRIVPPGKGIIHQVNLEYLSTVVAKAEVKGLLTAFPEVIIGTDSH 202
Query: 143 TPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
T +A V+ P+ L P+VIGV+LTG++ +P DV+L + +
Sbjct: 203 TTMIEGLGILGWGVGGLEAEAVLLGEPYYLNVPEVIGVRLTGEIQEGVTPTDVVLYITEL 262
Query: 323 LTVK 334
L K
Sbjct: 263 LRKK 266
>UniRef50_Q58409 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=7; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 1 -
Methanococcus jannaschii
Length = 420
Score = 58.4 bits (135), Expect = 3e-08
Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Frame = +2
Query: 38 KYGV-GFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMA 214
++G+ F K G GI HQI+ ENY P + + G DSHT D + A
Sbjct: 84 RFGIKNFHKGGEGICHQILAENYVLPNMFVAGGDSHTCTHGAFGAFATGFGATDMAYIYA 143
Query: 215 NIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+K PK I V + GK S KD++L+V + +G T
Sbjct: 144 TGETWIKVPKTIRVDIVGKNEN-VSAKDIVLRVCKEIGRRGAT 185
>UniRef50_Q1IMD4 Cluster: Aconitate hydratase-like; n=1;
Acidobacteria bacterium Ellin345|Rep: Aconitate
hydratase-like - Acidobacteria bacterium (strain
Ellin345)
Length = 655
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
YK +E + G+ F+ G+GI HQI++E Y P ++ +DSH+
Sbjct: 81 YKLIEKFAHEQGIDFYMAGTGIGHQIMVERGYVVPESFVVASDSHSNMYGAMGAIGTPVV 140
Query: 188 XADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
DA + A + P+ I V L GKL + KDVI+ +AG+
Sbjct: 141 RTDAAAIWATGEFWWSIPRTIQVVLEGKLRPGVTGKDVIITLAGL 185
>UniRef50_Q2GN26 Cluster: Homoaconitase, mitochondrial precursor;
n=9; Pezizomycotina|Rep: Homoaconitase, mitochondrial
precursor - Chaetomium globosum (Soil fungus)
Length = 797
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIIL-ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
YK +E ++GV F+ G GI HQI++ E YA+PG L + +DSH+
Sbjct: 159 YKNIENFARQHGVDFYPAGRGIGHQIMIEEGYAWPGTLTVASDSHSNMYGGVAALGTPVV 218
Query: 188 XADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
DA + A + P + V TG L + KDVI+ + +
Sbjct: 219 RTDAASIWATGQTWWQIPPIAKVTFTGVLPRGVTGKDVIIALCAL 263
>UniRef50_A5ZNE1 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 416
Score = 56.8 bits (131), Expect = 9e-08
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
Frame = +2
Query: 47 VGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAV-DVMANIP 223
+ FW+ G G+ HQ+++ENY PG L+ G DSHT + D + ++
Sbjct: 92 IDFWE-GKGVCHQVMIENYVRPGELIFGADSHTCSYGALGAFGTGVGCTDFLYGMVTGTS 150
Query: 224 WELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
W L P+ + LTGKL + +D+IL + G + G
Sbjct: 151 WVL-VPESVKFNLTGKLPEGVTARDLILTIIGEVGANG 187
>UniRef50_Q5PXM8 Cluster: Aconitase A; n=3; Gammaproteobacteria|Rep:
Aconitase A - Vibrio cholerae
Length = 407
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/104 (30%), Positives = 49/104 (47%)
Frame = +2
Query: 26 TAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVD 205
+A +YG F P +IHQ + E A G +++G+DSHT + V
Sbjct: 121 SAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHT-RYGALGTMAVGEGGGELVK 179
Query: 206 VMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
+ N W++ P V+ V LTGK + P+DV L + G + G
Sbjct: 180 QLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNG 223
>UniRef50_P75764 Cluster: Uncharacterized protein ybhJ; n=32;
Bacteria|Rep: Uncharacterized protein ybhJ - Escherichia
coli (strain K12)
Length = 753
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/104 (30%), Positives = 49/104 (47%)
Frame = +2
Query: 26 TAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVD 205
+A +YG F P +IHQ + E A G +++G+DSHT + V
Sbjct: 113 SAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHT-RYGALGTMAVGEGGGELVK 171
Query: 206 VMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
+ N W++ P V+ V LTGK + P+DV L + G + G
Sbjct: 172 QLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNG 215
>UniRef50_P81291 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=3; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 2 -
Methanococcus jannaschii
Length = 424
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/111 (31%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Frame = +2
Query: 14 KFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXX 190
KF++ G KY F+ G+ HQ++ E + PG +++G DSHT
Sbjct: 84 KFVKEQGIKY---FYDIREGVCHQVLPEKGHVAPGEVVVGADSHTCTHGAFGAFATGIGS 140
Query: 191 ADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
D V A K P+ I +TG L + + KDVIL + G + V G T
Sbjct: 141 TDMAHVFATGKLWFKVPETIYFNITGDLQPYVTSKDVILSIIGEVGVDGAT 191
>UniRef50_Q0W1Q4 Cluster: 3-isopropylmalate dehydratase, large
subunit; n=2; Euryarchaeota|Rep: 3-isopropylmalate
dehydratase, large subunit - Uncultured methanogenic
archaeon RC-I
Length = 414
Score = 54.8 bits (126), Expect = 4e-07
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 35 AKYGV-GFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDV 208
A+ G+ + G GI HQ++ EN +A PG +++G DSH+ D ++
Sbjct: 85 AEQGIKNLYDVGEGICHQLLPENGFAMPGKVIVGADSHSCTYGAFGAFATGVGATDMAEI 144
Query: 209 MANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ + P+ I + + GKL +PKDVIL++A + G T
Sbjct: 145 YTSGKLWFRVPETIKLTVDGKLPAAVTPKDVILRIAKEVGSDGAT 189
>UniRef50_Q125M5 Cluster: Aconitate hydratase-like; n=8;
Proteobacteria|Rep: Aconitate hydratase-like -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 888
Score = 54.4 bits (125), Expect = 5e-07
Identities = 43/118 (36%), Positives = 54/118 (45%), Gaps = 15/118 (12%)
Frame = +2
Query: 5 EVYKFLETAGAKY-GVGFWKPGSGIIHQIILEN--------------YAFPGLLMIGTDS 139
E Y+FL A GV PG+GI+H I LE +A P + MIGTDS
Sbjct: 151 ERYRFLRWASRVLSGVRIHPPGTGIMHTINLEQLATVVTTEERGGRLWAVPDM-MIGTDS 209
Query: 140 HTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
HTP +A VM +P L+ P VIGV+LTG+L D+ L V
Sbjct: 210 HTPMINGIGVLGWGVGGLEAQTVMFGMPTMLRIPDVIGVRLTGRLPPAAQSTDLALTV 267
>UniRef50_Q9RNH9 Cluster: Aconitase; n=3; Bacteria|Rep: Aconitase -
Streptomyces coelicolor
Length = 904
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 11/123 (8%)
Frame = +2
Query: 2 KEVYKFLETAGAKYG-VGFWKPGSGIIHQIILENYA----------FPGLLMIGTDSHTP 148
KE Y+FL + PG+GI+HQ+ +E+ A +P L +GTDSHT
Sbjct: 149 KERYQFLRWGQTAFDDFKVVPPGTGIVHQVNIEHLARVVMTRDGKAYPDTL-VGTDSHTT 207
Query: 149 NXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILT 328
+A M P + P+V+G KLTG+LT T+ D++L + +L
Sbjct: 208 MVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGELTPGTTATDLVLTITEMLR 267
Query: 329 VKG 337
G
Sbjct: 268 KHG 270
>UniRef50_Q9RTY9 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=10; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit 1 - Deinococcus radiodurans
Length = 434
Score = 54.0 bits (124), Expect = 7e-07
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Frame = +2
Query: 35 AKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVM 211
AK GV + G GI HQ+++E A PG +++G+DSH+ D
Sbjct: 102 AKTGVRLFDVGRGICHQVLMEEKLAQPGWIVLGSDSHSTTYGAVAAFGSGMGATDIALAA 161
Query: 212 ANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
A+ L+ P+ + V LTG L + KDV L++ +L G T
Sbjct: 162 ASGKTWLRVPESVKVTLTGDLRPGVTAKDVALEMIRVLGADGAT 205
>UniRef50_A5ZND9 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 423
Score = 53.6 bits (123), Expect = 9e-07
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Frame = +2
Query: 38 KYGVGFWKPGSGIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMA 214
KYG+ GI HQ++ E Y PG ++ GTDSHT + ++
Sbjct: 96 KYGMKNVHRSDGICHQLMTEAGYVKPGNIVFGTDSHTTTYGCVGAFSSGIGYTEMASILG 155
Query: 215 NIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+K P+ I V + G+L KDVIL++ G L G T
Sbjct: 156 TGTMWIKVPETIKVVIDGELPANVMSKDVILRLIGDLGADGAT 198
>UniRef50_P49367 Cluster: Homoaconitase, mitochondrial precursor;
n=14; Dikarya|Rep: Homoaconitase, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 693
Score = 53.2 bits (122), Expect = 1e-06
Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
YK +E K+ + + G GI HQI++E YAFP + + +DSH+
Sbjct: 100 YKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIV 159
Query: 188 XADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
DA + A + P V V+L G+L S KD+I+ + G+
Sbjct: 160 RTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGL 204
>UniRef50_Q42560 Cluster: Aconitate hydratase 1; n=35; cellular
organisms|Rep: Aconitate hydratase 1 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 898
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/122 (33%), Positives = 57/122 (46%), Gaps = 10/122 (8%)
Frame = +2
Query: 2 KEVYKFLET-AGAKYGVGFWKPGSGIIHQIILENYA-----FPGLL----MIGTDSHTPN 151
KE + FL+ + A + + PGSGI+HQ+ LE A GLL ++GTDSHT
Sbjct: 155 KERFAFLKWGSNAFHNMLVVPPGSGIVHQVNLEYLARVVFNTNGLLYPDSVVGTDSHTTM 214
Query: 152 XXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTV 331
+A M P + P V+G KLTGKL + D++L V +L
Sbjct: 215 IDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVVGFKLTGKLRDGMTATDLVLTVTQMLRK 274
Query: 332 KG 337
G
Sbjct: 275 HG 276
>UniRef50_UPI00015BAFD3 Cluster: 3-isopropylmalate dehydratase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: 3-isopropylmalate
dehydratase - Ignicoccus hospitalis KIN4/I
Length = 429
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Frame = +2
Query: 38 KYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADA-VDVM 211
K+ + G+GI HQ+++E A+PG + +G DSHT DA + +M
Sbjct: 88 KHKCTLYDVGTGICHQVMVEEGRAWPGSVFVGADSHTVTYGALGSFATGVGSTDAAIAMM 147
Query: 212 ANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
W K P+ + L GK KD+ILK+ G L G T
Sbjct: 148 TGRIW-FKVPEALKFNLIGKFREGVMSKDLILKIIGDLKEDGAT 190
>UniRef50_A0HK99 Cluster: Aconitate hydratase-like; n=3;
Burkholderiales|Rep: Aconitate hydratase-like -
Comamonas testosteroni KF-1
Length = 659
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/91 (29%), Positives = 44/91 (48%)
Frame = +2
Query: 68 SGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
+GI H ++ E YA PG L++GTDSHTP+ D + L P+
Sbjct: 325 AGISHAMMAECYALPGQLVVGTDSHTPHSGALGCVAFGIGTTDMANAFVTGAVRLTVPES 384
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+ + L G+L+ + KDV+L + ++ G
Sbjct: 385 LRIVLDGELSANVTAKDVVLHLLAQPYIRAG 415
>UniRef50_A3BB05 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 696
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Frame = +2
Query: 2 KEVYKFLETAG-AKYGVGFWKPGSGIIHQIILENYA-----FPGLL----MIGTDSHTPN 151
KE + FL+ A A + + + PGSGI+HQ+ LE A G++ ++GTDSHT
Sbjct: 9 KERFGFLKWASTAFHKMQVFPPGSGIVHQVNLEYLARVVFNADGIMYPDSVVGTDSHTTM 68
Query: 152 XXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTV 331
+A+ M P ++ P V+G KL+G L + D++L + +L
Sbjct: 69 INSLGVAGWGVGGIEAIVAMLGQPMDMVLPGVVGFKLSGMLRDGVTATDLVLTITQMLRK 128
Query: 332 KG 337
G
Sbjct: 129 HG 130
>UniRef50_Q97VY2 Cluster: 3-isopropylmalate dehydratase large
subunit; n=10; Thermoprotei|Rep: 3-isopropylmalate
dehydratase large subunit - Sulfolobus solfataricus
Length = 416
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Frame = +2
Query: 8 VYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
+ KF+++ G F+ GI+H++++E YA PG +++ DSHT
Sbjct: 83 IRKFVKSEGIP---NFYDINYGILHEVMIEQYANPGQVILAADSHTTTSGAVGAFAQGMG 139
Query: 188 XAD-AVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAG 319
+D A ++ W L P+ V L GK W + KDV LK+ G
Sbjct: 140 ASDIAAALITGKTW-LVVPQPFKVVLEGKPAKWITGKDVALKLLG 183
>UniRef50_Q9I3F5 Cluster: Aconitate hydratase 1; n=98; Bacteria|Rep:
Aconitate hydratase 1 - Pseudomonas aeruginosa
Length = 910
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Frame = +2
Query: 62 PGSGIIHQIILE--------------NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADA 199
PG+GI HQ+ LE YAFP L +GTDSHT +A
Sbjct: 175 PGTGICHQVNLEYLGRTVWTKDEDGRTYAFPDTL-VGTDSHTTMINGLGVLGWGVGGIEA 233
Query: 200 VDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
M P + P+VIG KLTGKL + D++L V +L KG
Sbjct: 234 EAAMLGQPVSMLIPEVIGFKLTGKLREGITATDLVLTVTQMLRKKG 279
>UniRef50_Q8TVF2 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=3; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 1 -
Methanopyrus kandleri
Length = 418
Score = 51.2 bits (117), Expect = 5e-06
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXX 178
K + +F+E G ++ F+ G+ HQ++ E + PG +++G DSHT
Sbjct: 79 KIMREFVEEQGIEH---FYDVREGVCHQVLPEKGHVRPGDVIVGADSHTCTHGALGAFAT 135
Query: 179 XXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
D V A + P+ V++TG+L KDV+LKV G + G T
Sbjct: 136 GIGSTDMAAVFATGKLWFRVPETYRVEITGELPEGVYAKDVVLKVTGEIGADGAT 190
>UniRef50_Q6NH63 Cluster: Aconitate hydratase; n=32; cellular
organisms|Rep: Aconitate hydratase - Corynebacterium
diphtheriae
Length = 934
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/123 (33%), Positives = 58/123 (47%), Gaps = 11/123 (8%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFW--KPGSGIIHQIILENYA---FP--GLLM----IGTDSHTP 148
+E Y+FL G+K F PG+GI+HQ+ +EN A F GL IGTDSHT
Sbjct: 151 EERYQFLRW-GSKAFSNFRVVPPGTGIVHQVNIENLARVVFDNNGLAYPDTCIGTDSHTT 209
Query: 149 NXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILT 328
+A M P + P+V+G KLTG++ + DV+L + +L
Sbjct: 210 MENGLGILGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPAGVTATDVVLTITEMLR 269
Query: 329 VKG 337
G
Sbjct: 270 EHG 272
>UniRef50_A6G875 Cluster: 3-isopropylmalate dehydratase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-isopropylmalate
dehydratase - Plesiocystis pacifica SIR-1
Length = 643
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
Frame = +2
Query: 2 KEVYKFLETAGAK-YGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXX 178
KE+ + E G + +G G K G+ H+I++E+YA PG +++ TDSHTP
Sbjct: 295 KEMIEACEKNGIRLHGPGRLK--QGVCHRIVVEDYARPGDIIVLTDSHTPTAGVMNAFAF 352
Query: 179 XXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAG 319
+ + PK + V + G G SPKD++L + G
Sbjct: 353 GVGSTAMAFALRTGMIPVTVPKTVRVWVEGDAKGVLSPKDLVLHLIG 399
>UniRef50_Q0ZQ48 Cluster: FrbA; n=6; cellular organisms|Rep: FrbA -
Streptomyces rubellomurinus
Length = 886
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 11/118 (9%)
Frame = +2
Query: 5 EVYKFLETAGAKY-GVGFWKPGSGIIHQIILENYA---FP---GLL----MIGTDSHTPN 151
E Y+FL A + G+ PG GI+HQ+ LE+ A P GL+ ++GTDSHTP
Sbjct: 160 ERYRFLRWAQQEISGLRVVPPGRGIVHQMHLEHLARVVLPDGDGLIAPDTVLGTDSHTPM 219
Query: 152 XXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
+A V+ L P+VIGV+LTG+L ++ D+ L + L
Sbjct: 220 VGALGVLGWGVGGIEAETVLLGHSVSLLSPQVIGVRLTGELPVGSTATDLALTMTEFL 277
>UniRef50_A5C294 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 885
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 10/122 (8%)
Frame = +2
Query: 2 KEVYKFLET-AGAKYGVGFWKPGSGIIHQIILEN-----YAFPGLL----MIGTDSHTPN 151
KE + FL+ + A + + PGSGI+HQ+ LE + G+L ++GTDSHT
Sbjct: 127 KERFGFLKWGSNAFHNMLVVPPGSGIVHQVNLEYLGRVVFNTEGILYPDSVVGTDSHTTM 186
Query: 152 XXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTV 331
+A M P + P V+G KL+GKL + D++L V +L
Sbjct: 187 IDGLGVAGWGVGGIEAEAAMLGQPMSMVLPGVVGFKLSGKLRDGVTATDLVLTVTQMLRK 246
Query: 332 KG 337
G
Sbjct: 247 HG 248
>UniRef50_A7DAM6 Cluster: Aconitate hydratase domain protein; n=1;
Methylobacterium extorquens PA1|Rep: Aconitate hydratase
domain protein - Methylobacterium extorquens PA1
Length = 908
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 15/126 (11%)
Frame = +2
Query: 5 EVYKFLETAGAKY-GVGFWKPGSGIIHQIILE--------------NYAFPGLLMIGTDS 139
E Y FL+ + + PG+GI HQ+ LE A+P L +GTDS
Sbjct: 157 ERYTFLKWGQSAFDNFSVVPPGTGICHQVNLEYLSQTVWTRTEDGAEIAYPDSL-VGTDS 215
Query: 140 HTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAG 319
HT +A M P + P+VIG KL+GKL T+ D++L V
Sbjct: 216 HTTMVNGLAVLGWGVGGIEAEAAMLGQPLSMLIPEVIGFKLSGKLPEGTTATDLVLTVTQ 275
Query: 320 ILTVKG 337
+L KG
Sbjct: 276 MLRKKG 281
>UniRef50_A6NVP4 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 396
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Frame = +2
Query: 38 KYGVGFWKPGSGIIHQIILENY-AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMA 214
++GV + G G+IHQ++ E + A PG L+ DSHT + MA
Sbjct: 86 EFGVHLYHRGEGVIHQLMYEKHRANPGDLIAIADSHTGTCGGYGVMGVGVGSTELAAAMA 145
Query: 215 NIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
+L+ P+V+ + LTGK KD+IL + +
Sbjct: 146 TGKLDLEVPQVVQIHLTGKKPANVFGKDLILYLGSV 181
>UniRef50_O67078 Cluster: 3-isopropylmalate dehydratase large
subunit; n=50; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Aquifex aeolicus
Length = 432
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXX 178
K V +F++ G K+ F++ G GI H I+ E PG L++G DSHT
Sbjct: 80 KIVREFVKKHGIKW---FFEEGEGIEHAILPEQGLVVPGDLVVGADSHTCTYGALGAFAT 136
Query: 179 XXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
D MA L+ P+ + GKL W KD+IL G + V G
Sbjct: 137 GVGSTDIAYAMATGEVWLRVPESMKFIFYGKLKPWVMGKDLILYTIGQIGVDG 189
>UniRef50_Q4T087 Cluster: Chromosome undetermined SCAF11289, whole
genome shotgun sequence; n=3; Euteleostomi|Rep:
Chromosome undetermined SCAF11289, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 894
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Frame = +2
Query: 2 KEVYKFLETAGAKY-GVGFWKPGSGIIHQIILENYAF-----PGLL----MIGTDSHTPN 151
+E ++FL+ + + PGSGI+HQ+ LE A GL+ ++GTDSHT
Sbjct: 144 RERFQFLKWGSRAFRNMRIIPPGSGIVHQVNLEYLARVVFQRDGLVYPDSVVGTDSHTTM 203
Query: 152 XXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
+A VM P + P+V+G +L+G G+ + D++L V
Sbjct: 204 IDGLGVLGWGVGGIEAEAVMLGQPISMVLPQVVGYRLSGVPDGFVTSTDIVLTV 257
>UniRef50_A5WEQ7 Cluster: 2-methylisocitrate dehydratase,
Fe/S-dependent; n=155; cellular organisms|Rep:
2-methylisocitrate dehydratase, Fe/S-dependent -
Psychrobacter sp. PRwf-1
Length = 903
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 16/108 (14%)
Frame = +2
Query: 62 PGSGIIHQIILENY----------------AFPGLLMIGTDSHTPNXXXXXXXXXXXXXA 193
PG+GI+HQI LE A+P L +GTDSHTP
Sbjct: 192 PGNGIMHQINLEKMSPVVQVITDKNDGTPVAYPDTL-VGTDSHTPMVDALGVISIGVGGL 250
Query: 194 DAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
+A VM P ++ P +IG++LTGKL + D++L + L +G
Sbjct: 251 EAESVMLGNPSYMRLPDIIGLELTGKLQPGITGTDLVLAMTEFLRDEG 298
>UniRef50_Q5V7D3 Cluster: Aconitate hydratase I; n=4; cellular
organisms|Rep: Aconitate hydratase I - Haloarcula
marismortui (Halobacterium marismortui)
Length = 927
Score = 47.6 bits (108), Expect = 6e-05
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 14/98 (14%)
Frame = +2
Query: 62 PGSGIIHQIILE--------------NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADA 199
PG+GI+HQ+ LE N+ P L +GTDSHTP +A
Sbjct: 175 PGTGIVHQVNLEHLGRVVHAREQDGENWLLPDTL-VGTDSHTPMIGGIGVVGWGVGGIEA 233
Query: 200 VDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
M P +K P+V+GV+L G+L + D++L +
Sbjct: 234 EAAMLGQPVTMKLPEVVGVRLEGELPEGATATDLVLHI 271
>UniRef50_P21399 Cluster: Iron-responsive element-binding protein 1;
n=116; cellular organisms|Rep: Iron-responsive
element-binding protein 1 - Homo sapiens (Human)
Length = 889
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 11/115 (9%)
Frame = +2
Query: 2 KEVYKFLETAG-AKYGVGFWKPGSGIIHQIILE----------NYAFPGLLMIGTDSHTP 148
+E ++FL+ A + + PGSGIIHQ+ LE Y +P L +GTDSHT
Sbjct: 151 RERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSL-VGTDSHTT 209
Query: 149 NXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
+A VM P + P+VIG +L GK + D++L +
Sbjct: 210 MIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTI 264
>UniRef50_Q8NQ98 Cluster: Aconitate hydratase; n=10; Bacteria|Rep:
Aconitate hydratase - Corynebacterium glutamicum
(Brevibacterium flavum)
Length = 939
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 11/123 (8%)
Frame = +2
Query: 2 KEVYKFLETAGAKYG-VGFWKPGSGIIHQIILE----------NYAFPGLLMIGTDSHTP 148
+E Y+FL + PG+GI+HQ+ +E A+P IGTDSHT
Sbjct: 151 EERYQFLRWGSESFSNFRVVPPGTGIVHQVNIEYLARVVFDNEGLAYPDTC-IGTDSHTT 209
Query: 149 NXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILT 328
+A M P + P+V+G KLTG++ + DV+L + +L
Sbjct: 210 MENGLGILGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPVGVTATDVVLTITEMLR 269
Query: 329 VKG 337
G
Sbjct: 270 DHG 272
>UniRef50_Q7N5S3 Cluster: Similar to large subunit of
3-isopropylmalate dehydratase; n=1; Photorhabdus
luminescens subsp. laumondii|Rep: Similar to large
subunit of 3-isopropylmalate dehydratase - Photorhabdus
luminescens subsp. laumondii
Length = 413
Score = 46.0 bits (104), Expect = 2e-04
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Frame = +2
Query: 44 GVGFWKPGSGIIHQIILENYAF-PGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANI 220
GV + G GI H I LE F PG ++IG DSHT +D + M
Sbjct: 93 GVNIFARGEGISHLIALEEQWFQPGNIVIGADSHTCTGGAVQSLALGMGASDVLAAMLTG 152
Query: 221 PWELKCPKVIGVKLTGKLTGWTSPKDVIL 307
LK P+ + + ++G+ T KDV+L
Sbjct: 153 QTWLKVPETVSLSISGQPHPATRTKDVML 181
>UniRef50_A7NXJ3 Cluster: Chromosome chr5 scaffold_2, whole genome
shotgun sequence; n=8; Magnoliophyta|Rep: Chromosome
chr5 scaffold_2, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 507
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Frame = +2
Query: 71 GIIHQIIL-ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
G+ H + E + PG +++GTDSHT DA V+ LK P
Sbjct: 193 GVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAAFVLGTGKILLKVPPT 252
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ + G++ + KD+IL++ G ++V G T
Sbjct: 253 LRFVMDGEMPNYLLAKDLILQIIGEISVSGAT 284
>UniRef50_Q9RTI6 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=3; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit 2 - Deinococcus radiodurans
Length = 431
Score = 45.2 bits (102), Expect = 3e-04
Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +2
Query: 5 EVYKFLETAGAKYGVG-FWKPGSGIIHQIILENYAF--PGLLMIGTDSHTPNXXXXXXXX 175
++Y+ L++ + G+ F+ G G I ++LEN PG ++ DSHT N
Sbjct: 77 KMYQKLKSWVQEKGIEHFYDVGRGGIAHVVLENTGLMKPGQTLVSGDSHTCNAGALGAFA 136
Query: 176 XXXXXAD-AVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
D A + A W K P+ + +++TGK +PKD++L+V
Sbjct: 137 TGVGSTDLAGAIYAGKVW-FKVPETMLIRVTGKTNPGVTPKDIVLEV 182
>UniRef50_Q0ADB7 Cluster: Aconitate hydratase 1; n=5; Bacteria|Rep:
Aconitate hydratase 1 - Nitrosomonas eutropha (strain
C71)
Length = 947
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGV-GFWKPGSGIIHQIILE----------NYAFPGLLMIGTDSHTP 148
+E Y+F++ + G PG GI+HQ+ LE + +P L +GTDSHT
Sbjct: 155 RERYQFIKWGMQAFDTFGVVPPGIGIVHQVNLEYLARGVHQKDGFIYPDTL-VGTDSHTT 213
Query: 149 NXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
+A M P P V+GV LTG L + D++L V +L
Sbjct: 214 MINGIGVVGWGVGGIEAEAGMLGQPIYFLTPDVVGVNLTGHLQEGVTATDLVLTVTEML 272
>UniRef50_A6DRT0 Cluster: 3-isopropylmalate dehydratase; n=4;
Bacteria|Rep: 3-isopropylmalate dehydratase -
Lentisphaera araneosa HTCC2155
Length = 433
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Frame = +2
Query: 53 FWKPGS----GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMAN 217
+++PG+ G+ H + E + PG +++GTDSHT DA M
Sbjct: 96 YYQPGTDNYMGVCHVTLPEKGHVRPGEIILGTDSHTCTHGALGAFATGIGNTDAAFTMGT 155
Query: 218 IPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
LK P+ I L GKL KD+IL + G + G T
Sbjct: 156 GRTWLKIPETIKFVLNGKLPKTMMAKDLILHMIGEIGFSGAT 197
>UniRef50_A0ZF76 Cluster: 3-isopropylmalate dehydratase, LeuC
subunit; n=2; Nostocaceae|Rep: 3-isopropylmalate
dehydratase, LeuC subunit - Nodularia spumigena CCY 9414
Length = 574
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Frame = +2
Query: 68 SGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPK 244
+GI H ++ E + PG+++ GTDSHT D ++ A ++ P
Sbjct: 256 AGICHVLLPEKGFVRPGMIIAGTDSHTCTYGALGAFSAGVGTTDMANIYAMGDMWIRVPS 315
Query: 245 VIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ +L+G L S KD+IL + G + G T
Sbjct: 316 TLVFELSGTLPPHISAKDIILFILGQIGCAGAT 348
>UniRef50_Q7WB80 Cluster: Aconitate hydratase; n=3; Bordetella|Rep:
Aconitate hydratase - Bordetella parapertussis
Length = 894
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 15/126 (11%)
Frame = +2
Query: 11 YKFLETAGAKY-GVGFWKPGSGIIHQIILE--------------NYAFPGLLMIGTDSHT 145
Y+FL+ A + G+ + PG+GIIHQ+ LE +A P +IG DSHT
Sbjct: 159 YRFLKWAQQAFDGLRVFAPGTGIIHQVNLEKLATVVSTSEHGGQQWACPD-FVIGGDSHT 217
Query: 146 PNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
P DA + + P+V+GV+L G + D L V L
Sbjct: 218 PMVNGLGVLGWGVGGIDAESALLGRAYTFPIPEVVGVELKGAFRSPVTTTDAALLVTQRL 277
Query: 326 TVKGGT 343
+G T
Sbjct: 278 RAEGVT 283
>UniRef50_Q8TW29 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=1; Methanopyrus kandleri|Rep:
3-isopropylmalate dehydratase large subunit 2 -
Methanopyrus kandleri
Length = 402
Score = 44.0 bits (99), Expect = 7e-04
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Frame = +2
Query: 71 GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
G+ HQ+++E YA PG ++ G DSHTP D + ++ P+
Sbjct: 97 GVCHQVLVEEGYAGPGRVVFGGDSHTPTSGAASALAFGFGGTDMAFALLYGELWIRVPRT 156
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGIL 325
+ V + G+L + KD+ L V G L
Sbjct: 157 VRVHVEGELEEPATAKDLALTVVGEL 182
>UniRef50_A1W553 Cluster: Aconitate hydratase 1 precursor; n=8;
Proteobacteria|Rep: Aconitate hydratase 1 precursor -
Acidovorax sp. (strain JS42)
Length = 972
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 12/120 (10%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGV-GFWKPGSGIIHQIILENYA-----------FPGLLMIGTDSHT 145
+E Y+F++ + G PG GI+HQ+ LE A +P L +GTDSHT
Sbjct: 160 RERYEFMKWGMQAFSTFGVVPPGFGIVHQVNLEYLARGVHKGNDGVYYPDTL-VGTDSHT 218
Query: 146 PNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
+A M P P V+G +L+G+L + D++L V IL
Sbjct: 219 TMINGIGVVGWGVGGIEAEAAMLGQPVYFLTPDVVGFELSGQLREGVTATDLVLTVTEIL 278
>UniRef50_Q89X98 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=52; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit 1 - Bradyrhizobium japonicum
Length = 477
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Frame = +2
Query: 59 KPGSGIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELK 235
+PG GI+H I E + PG L++ DSHT ++ V+A +
Sbjct: 112 QPGQGIVHVIGPELGLSLPGCLIVCGDSHTCTHGGLGALAFGIGSSELTHVLATQTIIQR 171
Query: 236 CPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
PK + V G++ + KD+IL + G + GGT
Sbjct: 172 RPKTMRVTFDGRMPFGVTAKDLILALIGHVGAAGGT 207
>UniRef50_Q8KER8 Cluster: 3-isopropylmalate dehydratase, large
subunit, putative; n=9; cellular organisms|Rep:
3-isopropylmalate dehydratase, large subunit, putative -
Chlorobium tepidum
Length = 431
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +2
Query: 71 GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIP-WELKCPK 244
G+ H + E + PG ++ GTDSHT DA ++ WE K P
Sbjct: 106 GVCHVALAEEGFNLPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTGKLWE-KVPD 164
Query: 245 VIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ G++ + + KD+IL++ G +T G T
Sbjct: 165 SMKFTFEGQMPEYLTAKDLILQILGDITTDGAT 197
>UniRef50_Q1LAU9 Cluster: Homoaconitate hydratase family protein;
n=8; Burkholderiales|Rep: Homoaconitate hydratase family
protein - Ralstonia metallidurans (strain CH34 / ATCC
43123 / DSM 2839)
Length = 440
Score = 42.7 bits (96), Expect = 0.002
Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXX 178
+ + +F + G+ + GI H ++ E + PG ++G DSH+P
Sbjct: 90 ESILRFTRDWVREAGIQNFIDNEGICHVVLPERGHILPGRFIVGGDSHSPTGGAFGAYMF 149
Query: 179 XXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+ V+A L+ P I V+ G L+ KD++L + L + GG
Sbjct: 150 GIGATEMAGVLATGEIWLRVPNTIRVEWQGTLSDGVCAKDIMLFLCATLGMAGG 203
>UniRef50_Q0C395 Cluster: Putative 3-isopropylmalate dehydratase,
large subunit; n=1; Hyphomonas neptunium ATCC 15444|Rep:
Putative 3-isopropylmalate dehydratase, large subunit -
Hyphomonas neptunium (strain ATCC 15444)
Length = 463
Score = 42.3 bits (95), Expect = 0.002
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 1/113 (0%)
Frame = +2
Query: 5 EVYKFLETAGAKYGVGFWKPGSGIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
E + +TAG + P GI+H + E A PGL ++ DSHT +
Sbjct: 86 ETREMAQTAGIHL-IDTDNPAQGIVHVVAPELGIALPGLTLVCPDSHTCSLGALGALAWG 144
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+DA MA P+ + +++ G+L+ S KD+ L + GG
Sbjct: 145 IGSSDAEHAMATGTLRAAKPRQMLIRVAGRLSPGVSAKDLALYIIARFGSDGG 197
>UniRef50_Q5P0Q2 Cluster: Aconitase; n=4; Proteobacteria|Rep:
Aconitase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 905
Score = 41.9 bits (94), Expect = 0.003
Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 14/102 (13%)
Frame = +2
Query: 62 PGSGIIHQIILENYAFPGL--------------LMIGTDSHTPNXXXXXXXXXXXXXADA 199
PG GI+HQ+ LE Y F G+ ++GTDSHT +A
Sbjct: 176 PGIGIVHQVNLE-YLFRGVRGHDTGDGMLYYPDTLVGTDSHTTMINGLGVVGWGVGGIEA 234
Query: 200 VDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
M P L P V+GV+L G+L + D++L V +L
Sbjct: 235 EAGMLGQPVYLLTPDVVGVELKGRLNEGVTATDLVLTVTELL 276
>UniRef50_Q1AVC5 Cluster: Homoaconitate hydratase family protein;
n=2; Bacteria|Rep: Homoaconitate hydratase family
protein - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 424
Score = 41.5 bits (93), Expect = 0.004
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Frame = +2
Query: 44 GVGFWKPG-SGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMAN 217
GV ++ G GI H +++E+ + PG+++ G DSHT D +A
Sbjct: 90 GVYYYGQGRGGIEHTVLVEDGWIVPGMVIAGGDSHTCTYGALGAFGTGLGSTDIAACLAF 149
Query: 218 IPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+ + P I V+ TG + + KD+IL V + V GG
Sbjct: 150 GEFWQQVPGTIQVEFTGHKGSFVAGKDLILAVIADIGVGGG 190
>UniRef50_Q6L0K5 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; Thermoplasmatales|Rep: 3-isopropylmalate
dehydratase large subunit - Picrophilus torridus
Length = 413
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 2/103 (1%)
Frame = +2
Query: 11 YKFLETAGAKYGVGFWKPG-SGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXX 184
YK ++ K+ F+ G G+ HQ+++E +A PG L+ G DSHT
Sbjct: 75 YKKVKDFALKHNTHFYDLGRGGVCHQVMMEKGFAAPGRLIAGADSHTNTYGALSCVSVGI 134
Query: 185 XXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
+A + K P+ +++ G+ KD+IL V
Sbjct: 135 GSTEAGVIFGTGRMWFKVPETDLIRINGRPKKGVYGKDIILNV 177
>UniRef50_Q8PUG1 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=30; Archaea|Rep: 3-isopropylmalate
dehydratase large subunit 2 - Methanosarcina mazei
(Methanosarcina frisia)
Length = 420
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Frame = +2
Query: 71 GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
G+ HQ++ E + PG L++G+DSHT D V A + P+
Sbjct: 100 GVCHQVLPEKGHVKPGDLIVGSDSHTCAYGSLGAFSTGIGSTDMAAVFATGKLWFRVPET 159
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
++ GKL KD+IL + G + V+G
Sbjct: 160 FRFEVEGKLPERVYSKDLILHLIGDVGVEG 189
>UniRef50_A4FHT3 Cluster: Aconitate hydratase 1; n=2;
Actinomycetales|Rep: Aconitate hydratase 1 -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 711
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/69 (31%), Positives = 30/69 (43%)
Frame = +2
Query: 131 TDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILK 310
TDSHTP A M P ++ P V+GV+LTG+L + D+ L
Sbjct: 31 TDSHTPMVNSIGVLGWGVGGLQAQAAMVGEPTAIRFPTVVGVRLTGRLRSGVTATDLALT 90
Query: 311 VAGILTVKG 337
V +L G
Sbjct: 91 VTELLRAHG 99
>UniRef50_Q2GXH4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 605
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/79 (27%), Positives = 36/79 (45%)
Frame = +2
Query: 86 IILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLT 265
++ E +A+PG + + +DSH + DA + A P + V+LT
Sbjct: 132 MVEEGHAWPGTMAVASDSHGTHYGGVGCLGTPVVRTDACSICATDRTWCNVPPIARVRLT 191
Query: 266 GKLTGWTSPKDVILKVAGI 322
G L + KDVI+ + GI
Sbjct: 192 GTLPQGVTGKDVIVALCGI 210
>UniRef50_P07264 Cluster: 3-isopropylmalate dehydratase; n=473;
cellular organisms|Rep: 3-isopropylmalate dehydratase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 779
Score = 40.3 bits (90), Expect = 0.009
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Frame = +2
Query: 14 KFLETAGAKYGV---GFWKPGSGIIHQI-ILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
K LE ++GV G GI+H I E + PG ++ DSHT
Sbjct: 97 KTLENNVKQFGVPYFGMSDARQGIVHTIGPEEGFTLPGTTVVCGDSHTSTHGAFGSLAFG 156
Query: 182 XXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
++ V+A K + + + GKL+ + KD+IL + G++ GGT
Sbjct: 157 IGTSEVEHVLATQTIIQAKSKNMRITVNGKLSPGITSKDLILYIIGLIGTAGGT 210
>UniRef50_P48200 Cluster: Iron-responsive element-binding protein 2;
n=45; Euteleostomi|Rep: Iron-responsive element-binding
protein 2 - Homo sapiens (Human)
Length = 963
Score = 39.9 bits (89), Expect = 0.011
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Frame = +2
Query: 62 PGSGIIHQIILE----------NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVM 211
PG+G+ HQI LE + FP + +GTDSH + VM
Sbjct: 247 PGTGMAHQINLEYLSRVVFEEKDLLFPDSV-VGTDSHITMVNGLGILGWGVGGIETEAVM 305
Query: 212 ANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
+P L P+V+G +LTG + + DV+L +
Sbjct: 306 LGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGI 339
>UniRef50_A0RXN9 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; Thermoprotei|Rep: 3-isopropylmalate
dehydratase large subunit - Cenarchaeum symbiosum
Length = 429
Score = 39.5 bits (88), Expect = 0.015
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Frame = +2
Query: 38 KYGVGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMA 214
KYG+G + GI H + E PG + +G DSHT D V+
Sbjct: 105 KYGMGQY----GICHTLSHEEALVLPGEVYVGGDSHTNTTGALGAFACGLGHTDMAYVLL 160
Query: 215 NIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
K P+ + ++L G L KD IL++ G + GG
Sbjct: 161 YGKIWFKVPETVLLRLNGALPPHVMAKDYILRIIGDMGTDGG 202
>UniRef50_Q5FUG3 Cluster: 3-isopropylmalate dehydratase large
subunit; n=120; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 475
Score = 39.5 bits (88), Expect = 0.015
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 4/112 (3%)
Frame = +2
Query: 20 LETAGAKYGVGFW---KPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXX 187
LE A++GV ++ GI+H + E + PG+ ++ DSHT
Sbjct: 91 LEKNVAEFGVPYFPLRSASQGIVHVVGPEQGISLPGMTIVCGDSHTSTHGALGSLAFGIG 150
Query: 188 XADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
++ V+A K K + V + GK+ + KD++L + G + GGT
Sbjct: 151 TSEVEHVLATQTILQKPAKNMRVSVEGKVGPGVTAKDILLAIIGRIGTAGGT 202
>UniRef50_Q65VS0 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=7; Proteobacteria|Rep: 3-isopropylmalate
dehydratase large subunit 1 - Mannheimia
succiniciproducens (strain MBEL55E)
Length = 475
Score = 39.5 bits (88), Expect = 0.015
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 PGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKC 238
P GI H + E A PG+++ DSHT ++ ++A K
Sbjct: 109 PRQGIEHVVAHEQGLALPGMVIAAGDSHTTTYGAFGAFGFGIGTSEIEHLLATQTLVYKK 168
Query: 239 PKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
K + V LTGKL T+ KDVI+ + + G T
Sbjct: 169 LKNMRVTLTGKLPFGTTAKDVIMALVAKIGADGAT 203
>UniRef50_Q8U0C0 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=4; Thermococcaceae|Rep: 3-isopropylmalate
dehydratase large subunit 2 - Pyrococcus furiosus
Length = 380
Score = 39.1 bits (87), Expect = 0.020
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 65 GSGIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCP 241
G GI HQ+++E +++G DSHTP D ++ + P
Sbjct: 84 GQGISHQLVVEMGLTENSKIVVGADSHTPTLGALGVFAVGMGATDVAVILGLGKTWFRIP 143
Query: 242 KVIGVKLTGKLTGWTSPKDVILKVAGIL 325
+ +GV L G + + DVIL + +L
Sbjct: 144 ESVGVILEGNPSRYVMATDVILHLLSLL 171
>UniRef50_A7CSQ0 Cluster: Aconitate hydratase 1; n=1; Opitutaceae
bacterium TAV2|Rep: Aconitate hydratase 1 - Opitutaceae
bacterium TAV2
Length = 965
Score = 38.7 bits (86), Expect = 0.026
Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Frame = +2
Query: 62 PGSGIIHQIILENYAFPGLL-----------MIGTDSHTPNXXXXXXXXXXXXXADAVDV 208
PG GI+HQ+ LE Y G+L ++GTDSHT +A
Sbjct: 179 PGIGIVHQVNLE-YLAQGVLKDANSICYPDTLVGTDSHTTMINGIGIVGWGVGGIEAEAG 237
Query: 209 MANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
M P P V+GV LTG L + D+ L + +L
Sbjct: 238 MLGQPVYFLTPDVVGVYLTGALREGVTATDLALTLTQLL 276
>UniRef50_Q4WBR0 Cluster: Aconitase family protein; n=7;
Pezizomycotina|Rep: Aconitase family protein -
Aspergillus fumigatus (Sartorya fumigata)
Length = 811
Score = 38.7 bits (86), Expect = 0.026
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 1/105 (0%)
Frame = +2
Query: 2 KEVYKFLETAGAKYGVGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXX 181
K V+K E G Y I+H A PG+L+IG+DSHT +
Sbjct: 223 KRVFKLTEYQGMNYT---------ILHTEFYRERAQPGMLIIGSDSHTCSSGALGCLAIG 273
Query: 182 XXXAD-AVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
AD + ++ W +K P+ I ++L G KDVIL +
Sbjct: 274 LGAADVTLPLVTGETW-VKVPESISIRLVGVPKPGIGGKDVILYI 317
>UniRef50_UPI00006D922D Cluster: COG0065: 3-isopropylmalate
dehydratase large subunit; n=1; Pseudomonas aeruginosa
2192|Rep: COG0065: 3-isopropylmalate dehydratase large
subunit - Pseudomonas aeruginosa 2192
Length = 329
Score = 38.3 bits (85), Expect = 0.035
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Frame = +2
Query: 71 GIIHQIILENYA-FPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
GI+H + E A PG+ ++ DSHT ++ V+A K K
Sbjct: 112 GIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKN 171
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+ VK+ G+L + KD++L V G + GG
Sbjct: 172 MLVKVEGRLPAGVTAKDIVLAVIGRIGTAGG 202
>UniRef50_Q74BX5 Cluster: 3-isopropylmalate dehydratase, large
subunit, putative; n=14; Bacteria|Rep: 3-isopropylmalate
dehydratase, large subunit, putative - Geobacter
sulfurreducens
Length = 427
Score = 38.3 bits (85), Expect = 0.035
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Frame = +2
Query: 14 KFLETAGAKYG-VGFWKPGS-GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXX 184
K L ++G V F+ G+ G+ H + E + PG +I DSHT
Sbjct: 78 KMLRDWARRHGIVDFFDVGANGVCHALFPEKGFIRPGYTVIMGDSHTCTHGAFGAFAAGI 137
Query: 185 XXADA-VDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
D V ++ + + PK I + L G L KDVIL V G + V G T
Sbjct: 138 GTTDLEVGILKGV-CAFREPKTIRINLNGSLPEGVYAKDVILHVIGRIGVNGAT 190
>UniRef50_Q4VDG4 Cluster: Putative 3-isopropylmalate dehydratase
large subunit; n=1; Hyaloperonospora parasitica|Rep:
Putative 3-isopropylmalate dehydratase large subunit -
Hyaloperonospora parasitica
Length = 714
Score = 38.3 bits (85), Expect = 0.035
Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 2/104 (1%)
Frame = +2
Query: 20 LETAGAK-YGVGFWKPGSG-IIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXA 193
+ TA AK +GV ++P + I+H A PG ++IG DSHT +
Sbjct: 93 MSTAFAKTHGVTDFQPANTTIMHTEFARKRAQPGQIIIGADSHTCSAGGMGAFAAGLGAG 152
Query: 194 DAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 325
D V + K P+V ++ G KDVIL + G L
Sbjct: 153 DVVMPLVTGQTWFKVPEVCYIEFVGAPHFGIGGKDVILHILGEL 196
>UniRef50_Q59938 Cluster: Aconitate hydratase; n=356; cellular
organisms|Rep: Aconitate hydratase - Streptococcus
mutans
Length = 888
Score = 38.3 bits (85), Expect = 0.035
Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 11/114 (9%)
Frame = +2
Query: 5 EVYKFLETAGAKY-GVGFWKPGSGIIHQIILE----------NYAFPGLLMIGTDSHTPN 151
E Y+FL+ A + P +GIIHQ+ LE + +P M GTDSHT
Sbjct: 150 ERYEFLKWAEKTFENYRAVPPATGIIHQVNLEFLSDVIINKDGFLYPDS-MFGTDSHTTM 208
Query: 152 XXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKV 313
+A M P+VIGV+L G+L + D+ LKV
Sbjct: 209 INGIGVLGWGVGGIEAEAAMLGEASYFPIPEVIGVRLYGELPKVATATDLALKV 262
>UniRef50_A3LRP7 Cluster: 3-isopropylmalate dehydratase; n=1; Pichia
stipitis|Rep: 3-isopropylmalate dehydratase - Pichia
stipitis (Yeast)
Length = 677
Score = 37.5 bits (83), Expect = 0.060
Identities = 22/84 (26%), Positives = 36/84 (42%)
Frame = +2
Query: 62 PGSGIIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCP 241
P + I+H A PG+L+IG DSHT + +D V + + P
Sbjct: 103 PNTTIMHTEFYRERAQPGMLIIGADSHTCSSGALGCLAVGLGTSDVVFPLITGETFFQIP 162
Query: 242 KVIGVKLTGKLTGWTSPKDVILKV 313
+ + +++ GK KD IL +
Sbjct: 163 ETLKIEIVGKPNFGIGGKDTILHI 186
>UniRef50_O08451 Cluster: Aconitate hydratase; n=21; Bacteria|Rep:
Aconitate hydratase - Mycobacterium avium
Length = 961
Score = 37.1 bits (82), Expect = 0.080
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Frame = +2
Query: 5 EVYKFLETAGAKYGVGFWKPGSGIIHQIILE----------NYAFPGLLMIGTDSHTPNX 154
E Y+FL + P I+HQ+ +E A+P +GTDSHT
Sbjct: 179 ERYQFLRWLQGAFSDFKVVPPRRIVHQVNIEYLARVVMERVGVAYPDTC-VGTDSHTTMV 237
Query: 155 XXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVK 334
+A M P + P+V+G KLTG+ + DV+L V I
Sbjct: 238 NGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEDPAPGAATDVVLTVTEICAKH 297
Query: 335 G 337
G
Sbjct: 298 G 298
>UniRef50_Q08N42 Cluster: Aconitate hydratase; n=2;
Cystobacterineae|Rep: Aconitate hydratase - Stigmatella
aurantiaca DW4/3-1
Length = 691
Score = 36.7 bits (81), Expect = 0.11
Identities = 23/84 (27%), Positives = 34/84 (40%)
Frame = +2
Query: 74 IIHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIG 253
I+H PG +++G DSHT + AD + L+ P+ I
Sbjct: 146 ILHTKFYRELVQPGQVVLGADSHTSSHGGLGAFAIGLGGADVTAALVLGQSWLEVPEAIA 205
Query: 254 VKLTGKLTGWTSPKDVILKVAGIL 325
V+ G+ KD+ILK G L
Sbjct: 206 VEYQGEPPFGIGGKDIILKTLGTL 229
>UniRef50_Q82WI9 Cluster: 3-isopropylmalate dehydratase large
subunit; n=81; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Nitrosomonas europaea
Length = 470
Score = 36.3 bits (80), Expect = 0.14
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +2
Query: 71 GIIHQIILENYA-FPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
GI+H I E A PG+ ++ DSHT ++ V+A + K
Sbjct: 108 GIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFACLAFGIGTSEVEHVLATQCLVARKSKT 167
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ V++ G L + KD+ L V G + GGT
Sbjct: 168 MLVRVEGDLPPGVTAKDIALAVIGEIGTAGGT 199
>UniRef50_A5WGT5 Cluster: 3-isopropylmalate dehydratase, large
subunit; n=11; Bacteria|Rep: 3-isopropylmalate
dehydratase, large subunit - Psychrobacter sp. PRwf-1
Length = 478
Score = 35.1 bits (77), Expect = 0.32
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +2
Query: 71 GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
GI+H + E PG+ ++ DSHT ++ V+A K K
Sbjct: 118 GIVHVVGPEQGLVLPGMTVVCGDSHTATHGALGCLAHGIGTSEVEHVLATQCLVQKKSKN 177
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
+ +++ G+L + KDV+L + + GGT
Sbjct: 178 MLIRVNGELGAGVTAKDVVLAIIAKIGTAGGT 209
>UniRef50_O53237 Cluster: 3-isopropylmalate dehydratase large
subunit; n=29; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Mycobacterium tuberculosis
Length = 473
Score = 35.1 bits (77), Expect = 0.32
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 4/106 (3%)
Frame = +2
Query: 35 AKYGVGFWKPGS---GIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAV 202
A++G+ G GI+H + + PG+ ++ DSHT ++
Sbjct: 98 AEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVE 157
Query: 203 DVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
V+A L+ K + V + G+L S KD+IL + + GG
Sbjct: 158 HVLATQTLPLRPFKTMAVNVDGRLPDGVSAKDIILALIAKIGTGGG 203
>UniRef50_A7H0L8 Cluster: 3-isopropylmalate dehydratase, large
subunit; n=1; Campylobacter curvus 525.92|Rep:
3-isopropylmalate dehydratase, large subunit -
Campylobacter curvus 525.92
Length = 421
Score = 33.5 bits (73), Expect = 0.98
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 1/90 (1%)
Frame = +2
Query: 71 GIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
GI H ++ E PG ++IG DSHT D M K P
Sbjct: 100 GIEHALLPEKGLIVPGDVIIGADSHTCTHGALGAFSTGMGSTDLAYAMITGKNWFKVPPT 159
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKG 337
I V GKL KD+IL++ + V G
Sbjct: 160 IKVVFRGKLGRHVYGKDLILEIIRQIGVDG 189
>UniRef50_Q18GT3 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Haloquadratum walsbyi
(strain DSM 16790)
Length = 488
Score = 33.5 bits (73), Expect = 0.98
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Frame = +2
Query: 71 GIIHQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKV 247
GI H + E + PG+ + DSHT + DV+A + +V
Sbjct: 109 GITHVVAPELGLSQPGMTVACGDSHTSTHGAFGSVGIGIGTSQIRDVLATGCIAAEKQQV 168
Query: 248 IGVKLTGKLTGWTSPKDVILKVAGILTVKGG 340
+++TG L+ KD+ILK+ L V GG
Sbjct: 169 RRIEVTGTLSEEVYAKDIILKIIRDLGVGGG 199
>UniRef50_Q05FR0 Cluster: 3-isopropylmalate dehydratase large
subunit; n=1; Candidatus Carsonella ruddii PV|Rep:
3-isopropylmalate dehydratase large subunit - Carsonella
ruddii (strain PV)
Length = 456
Score = 33.1 bits (72), Expect = 1.3
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Frame = +2
Query: 62 PGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXAD---AVDVMANIPWE 229
P GIIH I E+ PG++ I DSHT D + I +
Sbjct: 99 PKQGIIHIIASESKILLPGMIAICGDSHTTTNGALSLIANGIGTTDIEIGISTQCIIQKK 158
Query: 230 LKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVKGGT 343
LK K++ + L + KD+IL + +T KGGT
Sbjct: 159 LKNMKIV---INNFLNKNVTSKDLILFIIKKITSKGGT 193
>UniRef50_Q7WPW8 Cluster: Aconitase family protein; n=2;
Bordetella|Rep: Aconitase family protein - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 436
Score = 31.9 bits (69), Expect = 3.0
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Frame = +2
Query: 68 SGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPK 244
+GI HQ+ E+ + PG + IG D+ A+ +MA K P
Sbjct: 103 NGISHQVPAEHGWVLPGTVYIGADTQAATLGAFNCFAIPAL-AETPFIMATGDTWFKVPP 161
Query: 245 VIGVKLTGKLTGWTSPKDVILKV 313
+ ++L+G+L KD+ L++
Sbjct: 162 CVRIRLSGRLPKGVLGKDIYLRL 184
>UniRef50_A5WFV6 Cluster: Putative uncharacterized protein; n=1;
Psychrobacter sp. PRwf-1|Rep: Putative uncharacterized
protein - Psychrobacter sp. PRwf-1
Length = 1773
Score = 31.5 bits (68), Expect = 4.0
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 238 TLQLPRDVGHYVHSISTTDTNTQSTKATSI 149
TL LP+D+ Y+ + D+NTQ K S+
Sbjct: 975 TLHLPKDMAQYLQVLKAADSNTQLQKVKSV 1004
>UniRef50_A2Q8B9 Cluster: Contig An01c0120, complete genome; n=5;
Trichocomaceae|Rep: Contig An01c0120, complete genome -
Aspergillus niger
Length = 207
Score = 31.5 bits (68), Expect = 4.0
Identities = 11/35 (31%), Positives = 18/35 (51%)
Frame = +1
Query: 70 WYYPSDHSGELCVPWSTHDRHRLPHT*WRWPWWIV 174
W + + +C+ + TH +H H RWPW+ V
Sbjct: 82 WEHSKAVNMAICITFGTHGQHWNGHCLTRWPWFTV 116
>UniRef50_A5AFK5 Cluster: Putative uncharacterized protein; n=2;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 1324
Score = 31.1 bits (67), Expect = 5.3
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = +2
Query: 239 PKVIGVKLTGKLTGWTSPKDVILKVAGILTVK 334
PK+I L +L W SP V+LK +GI+ V+
Sbjct: 625 PKLILKPLPTELNPWVSPTQVVLKKSGIMVVQ 656
>UniRef50_A2QCU4 Cluster: Similarity to hypothetical DNA-binding
protein DF1 - Pisum sativum; n=1; Aspergillus niger|Rep:
Similarity to hypothetical DNA-binding protein DF1 -
Pisum sativum - Aspergillus niger
Length = 506
Score = 31.1 bits (67), Expect = 5.3
Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Frame = -1
Query: 339 PPFTVRMPATFKITSFGLVQPVSLPVNLT-PITL 241
PP ++ MP+T ++ ++QP ++ +LT PITL
Sbjct: 233 PPISIPMPSTTPEDNYPIIQPTTITTSLTHPITL 266
>UniRef50_Q6KZ03 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; Thermoplasmatales|Rep: 3-isopropylmalate
dehydratase large subunit - Picrophilus torridus
Length = 407
Score = 31.1 bits (67), Expect = 5.3
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 1/89 (1%)
Frame = +2
Query: 53 FWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWE 229
F+ GI H + EN + PG ++ TDSHT N + + V+A
Sbjct: 90 FFDYSGGISHVLAAENRWILPGSIIANTDSHTVNTGAYNSLGRGLGTPEIMSVIATGRTW 149
Query: 230 LKCPKVIGVKLTGKLTGWTSPKDVILKVA 316
+ I V L S KDV +A
Sbjct: 150 FIVGETINVVFKNYLKSNVSAKDVFFYMA 178
>UniRef50_UPI0000DD8049 Cluster: PREDICTED: similar to amyloid beta
(A4) precursor protein-binding, family B, member 1
interacting protein; n=1; Homo sapiens|Rep: PREDICTED:
similar to amyloid beta (A4) precursor protein-binding,
family B, member 1 interacting protein - Homo sapiens
Length = 143
Score = 30.7 bits (66), Expect = 6.9
Identities = 13/26 (50%), Positives = 14/26 (53%)
Frame = +1
Query: 88 HSGELCVPWSTHDRHRLPHT*WRWPW 165
HS + C PWST P T WR PW
Sbjct: 88 HSHQ-CRPWSTQSSRCRPRTSWRPPW 112
>UniRef50_Q57WV6 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma brucei|Rep: Putative uncharacterized protein
- Trypanosoma brucei
Length = 303
Score = 30.7 bits (66), Expect = 6.9
Identities = 18/56 (32%), Positives = 27/56 (48%)
Frame = -3
Query: 193 STTDTNTQSTKATSIRCVGVCADHE*TRERIVLQNDLMDNTRAGLPETDSIFSSGS 26
+TT T + KA+ +RC C D E ER + N LM + G+ E + + S
Sbjct: 54 TTTTTYNEYNKASPLRCESSCKDKEPQSERRLPVNSLM---QVGMEEQQPVSQASS 106
>UniRef50_Q49GP5 Cluster: Phosphatidylinositol 4-kinase type 2-beta;
n=7; Coelomata|Rep: Phosphatidylinositol 4-kinase type
2-beta - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 30.7 bits (66), Expect = 6.9
Identities = 15/36 (41%), Positives = 20/36 (55%)
Frame = +2
Query: 215 NIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGI 322
N W +K K +LT K + WT PKD +K+A I
Sbjct: 328 NDNWLIKYEKPGDGELTEKESEWTDPKDSAIKIAAI 363
>UniRef50_A1HNW5 Cluster: Benzoate transporter; n=2;
Clostridiales|Rep: Benzoate transporter - Thermosinus
carboxydivorans Nor1
Length = 413
Score = 30.3 bits (65), Expect = 9.2
Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 1/30 (3%)
Frame = -1
Query: 342 VPPFTVRMPA-TFKITSFGLVQPVSLPVNL 256
+PP + M A +TSFGLV+PVSL + L
Sbjct: 185 IPPIMIAMIAGAILLTSFGLVKPVSLNLQL 214
>UniRef50_P53656 Cluster: Adenosylmethionine-8-amino-7-oxononanoate
aminotransferase; n=4; Bacteria|Rep:
Adenosylmethionine-8-amino-7-oxononanoate
aminotransferase - Escherichia vulneris
Length = 429
Score = 30.3 bits (65), Expect = 9.2
Identities = 12/28 (42%), Positives = 18/28 (64%)
Frame = -3
Query: 337 SLHSQDAGHLQDHIFRTRPAGEFTGQFD 254
S+HS AG+L D++F P F G++D
Sbjct: 160 SMHSLWAGYLPDNLFAPAPESRFDGEWD 187
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 349,802,494
Number of Sequences: 1657284
Number of extensions: 6348297
Number of successful extensions: 16743
Number of sequences better than 10.0: 105
Number of HSP's better than 10.0 without gapping: 16327
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 16694
length of database: 575,637,011
effective HSP length: 89
effective length of database: 428,138,735
effective search space used: 10703468375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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