Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-0784
(774 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB004884-1|BAA20561.1| 719|Homo sapiens PKU-alpha protein. 377 e-104
AF162667-1|AAF03095.1| 749|Homo sapiens tousled-like kinase 2 p... 376 e-104
BC044925-1|AAH44925.2| 830|Homo sapiens TLK2 protein protein. 376 e-104
AB004885-1|BAA20562.1| 787|Homo sapiens PKU-beta protein. 376 e-104
D50927-1|BAA09486.2| 801|Homo sapiens KIAA0137 protein protein. 374 e-103
BC032657-1|AAH32657.1| 766|Homo sapiens tousled-like kinase 1 p... 374 e-103
AF246219-1|AAF71263.1| 549|Homo sapiens SNARE protein kinase SN... 374 e-103
AF162666-1|AAF03094.1| 718|Homo sapiens tousled-like kinase 1 p... 374 e-103
AC010092-1|AAY15077.1| 376|Homo sapiens unknown protein. 371 e-102
Z25421-1|CAA80908.1| 127|Homo sapiens protein-serine/threonine ... 149 8e-36
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 96 1e-19
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 96 1e-19
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 94 4e-19
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 94 4e-19
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 94 4e-19
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 94 4e-19
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 94 4e-19
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 89 1e-17
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 88 4e-17
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 88 4e-17
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 88 4e-17
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 88 4e-17
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 88 4e-17
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 87 7e-17
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 87 7e-17
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 87 7e-17
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 87 7e-17
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 87 9e-17
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 87 9e-17
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 86 2e-16
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 85 3e-16
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 85 3e-16
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 85 3e-16
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 85 3e-16
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 85 3e-16
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 85 3e-16
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 85 3e-16
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 85 3e-16
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 85 4e-16
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 85 4e-16
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 85 4e-16
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 85 4e-16
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 84 5e-16
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 84 5e-16
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 84 5e-16
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 84 6e-16
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 83 1e-15
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 83 1e-15
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 83 1e-15
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 83 1e-15
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 82 2e-15
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 82 2e-15
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 82 2e-15
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 82 2e-15
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 82 2e-15
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 82 2e-15
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 82 2e-15
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 81 3e-15
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 81 3e-15
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 81 3e-15
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 80 8e-15
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 80 8e-15
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 80 8e-15
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 80 8e-15
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 80 8e-15
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 80 8e-15
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 80 8e-15
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 80 1e-14
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 80 1e-14
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 80 1e-14
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 80 1e-14
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 80 1e-14
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 80 1e-14
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 80 1e-14
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 80 1e-14
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 80 1e-14
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 79 1e-14
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 79 1e-14
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 79 1e-14
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 79 1e-14
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 79 1e-14
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 79 1e-14
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 79 1e-14
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 79 1e-14
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 79 1e-14
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 79 1e-14
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 79 1e-14
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 79 1e-14
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 79 1e-14
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL162724-7|CAH70252.1| 222|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL162724-6|CAH70251.1| 220|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL162724-5|CAH70250.1| 219|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL162724-4|CAH70249.1| 207|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 79 1e-14
AL137846-11|CAI10881.1| 222|Homo sapiens NIMA (never in mitosis... 79 1e-14
AL137846-10|CAI10880.1| 220|Homo sapiens NIMA (never in mitosis... 79 1e-14
AL137846-9|CAI10879.1| 219|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL137846-8|CAI10878.1| 207|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 79 1e-14
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 79 1e-14
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 79 1e-14
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 79 1e-14
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 79 1e-14
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 79 1e-14
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 79 1e-14
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 79 1e-14
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 79 1e-14
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 79 1e-14
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 79 2e-14
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 79 2e-14
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 79 2e-14
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 79 2e-14
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 78 3e-14
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 78 3e-14
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 78 3e-14
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 78 3e-14
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 78 4e-14
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 78 4e-14
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 78 4e-14
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 78 4e-14
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 78 4e-14
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 78 4e-14
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 78 4e-14
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 78 4e-14
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 78 4e-14
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 78 4e-14
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 78 4e-14
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 77 5e-14
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 77 5e-14
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 77 5e-14
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 77 5e-14
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 77 5e-14
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 77 5e-14
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 77 5e-14
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 77 7e-14
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 77 9e-14
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 77 9e-14
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 77 9e-14
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 77 9e-14
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 77 9e-14
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 77 9e-14
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 77 9e-14
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 77 9e-14
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 77 9e-14
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 77 9e-14
AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 76 1e-13
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 76 2e-13
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 76 2e-13
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 76 2e-13
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 76 2e-13
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 76 2e-13
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 76 2e-13
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 76 2e-13
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 76 2e-13
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 75 2e-13
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 75 3e-13
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 75 3e-13
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 75 3e-13
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 75 3e-13
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 75 3e-13
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 75 3e-13
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 75 3e-13
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 75 3e-13
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 75 3e-13
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 75 3e-13
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 75 3e-13
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 75 3e-13
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 75 3e-13
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 75 3e-13
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 75 3e-13
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 75 3e-13
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 75 3e-13
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 75 3e-13
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 75 3e-13
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 75 3e-13
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 74 5e-13
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 73 9e-13
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 73 9e-13
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 73 9e-13
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 73 1e-12
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 73 1e-12
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 73 1e-12
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 73 1e-12
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 73 1e-12
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 73 1e-12
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 73 1e-12
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 73 1e-12
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 73 1e-12
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 73 1e-12
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 73 1e-12
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 73 1e-12
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 73 1e-12
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 73 2e-12
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 73 2e-12
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 73 2e-12
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 73 2e-12
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 73 2e-12
AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delt... 73 2e-12
Z84469-2|CAI42732.1| 1790|Homo sapiens WNK lysine deficient prot... 72 2e-12
Z84469-1|CAI42733.1| 1743|Homo sapiens WNK lysine deficient prot... 72 2e-12
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 72 2e-12
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 72 2e-12
AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase... 72 2e-12
AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase... 72 2e-12
AL591766-2|CAI40707.1| 1790|Homo sapiens WNK lysine deficient pr... 72 2e-12
AL591766-1|CAI40708.1| 1743|Homo sapiens WNK lysine deficient pr... 72 2e-12
AL049793-2|CAI43128.1| 1790|Homo sapiens WNK lysine deficient pr... 72 2e-12
AL049793-1|CAI43129.1| 1743|Homo sapiens WNK lysine deficient pr... 72 2e-12
AJ409088-1|CAC32455.2| 1743|Homo sapiens protein kinase WNK3 pro... 72 2e-12
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 72 2e-12
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 72 2e-12
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 72 3e-12
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 72 3e-12
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 72 3e-12
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 72 3e-12
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 72 3e-12
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 72 3e-12
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 72 3e-12
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 72 3e-12
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 72 3e-12
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 72 3e-12
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 72 3e-12
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 72 3e-12
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 71 4e-12
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 71 4e-12
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 71 4e-12
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 71 4e-12
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 71 4e-12
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 71 4e-12
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 71 4e-12
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 71 4e-12
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 71 4e-12
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 71 4e-12
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 71 4e-12
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 71 4e-12
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 71 4e-12
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 71 4e-12
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 71 4e-12
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 71 4e-12
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 71 4e-12
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 71 4e-12
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 71 4e-12
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 71 4e-12
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 71 4e-12
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 71 4e-12
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 71 4e-12
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 71 4e-12
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 71 5e-12
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 71 5e-12
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 70 8e-12
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 70 8e-12
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 70 8e-12
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 70 8e-12
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 70 8e-12
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 70 8e-12
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 70 8e-12
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 70 8e-12
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 70 8e-12
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 70 8e-12
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 70 8e-12
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 70 8e-12
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 70 8e-12
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 70 1e-11
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 70 1e-11
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 70 1e-11
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 70 1e-11
AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protei... 70 1e-11
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 70 1e-11
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 70 1e-11
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 70 1e-11
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 70 1e-11
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 70 1e-11
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 70 1e-11
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 70 1e-11
AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein. 70 1e-11
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 69 1e-11
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 69 1e-11
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 69 1e-11
BC094862-1|AAH94862.1| 393|Homo sapiens WNK1 protein protein. 69 1e-11
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 69 1e-11
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 69 1e-11
BC021121-1|AAH21121.1| 393|Homo sapiens WNK1 protein protein. 69 1e-11
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 69 1e-11
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 69 1e-11
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 69 1e-11
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 69 1e-11
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 69 1e-11
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 69 1e-11
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 69 1e-11
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 69 1e-11
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 69 1e-11
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 69 1e-11
AJ296290-1|CAC15059.1| 2382|Homo sapiens putative protein kinase... 69 1e-11
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 69 1e-11
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 69 1e-11
AF061944-1|AAF31483.1| 670|Homo sapiens kinase deficient protei... 69 1e-11
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 69 1e-11
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 69 1e-11
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 69 1e-11
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 69 1e-11
AB002342-1|BAA20802.2| 2066|Homo sapiens KIAA0344 protein. 69 1e-11
D63485-1|BAA09772.2| 723|Homo sapiens KIAA0151 protein. 69 2e-11
DQ667176-1|ABG25921.1| 716|Homo sapiens inhibitor of kappa ligh... 69 2e-11
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 69 2e-11
BC105924-1|AAI05925.1| 716|Homo sapiens IKK-related kinase epsi... 69 2e-11
BC105923-1|AAI05924.1| 716|Homo sapiens inhibitor of kappa ligh... 69 2e-11
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 69 2e-11
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 69 2e-11
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 69 2e-11
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 69 2e-11
AL354681-1|CAI15250.1| 716|Homo sapiens inhibitor of kappa ligh... 69 2e-11
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 69 2e-11
AF241789-1|AAF45307.1| 716|Homo sapiens IKK epsilon protein. 69 2e-11
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 69 2e-11
AB016590-1|BAA85155.1| 716|Homo sapiens inducible IkappaB kinas... 69 2e-11
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 69 2e-11
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 69 2e-11
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 69 2e-11
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 69 2e-11
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 69 2e-11
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 69 2e-11
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 69 2e-11
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 69 2e-11
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 69 2e-11
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 69 2e-11
AL583839-7|CAO03350.1| 2219|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL390760-3|CAO03647.1| 2219|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL390760-2|CAO03646.1| 790|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL356285-1|CAI15861.1| 1088|Homo sapiens LATS, large tumor suppr... 69 2e-11
AL354991-3|CAO03639.1| 2219|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient pr... 69 2e-11
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 69 2e-11
AL161613-1|CAH71526.1| 1088|Homo sapiens LATS, large tumor suppr... 69 2e-11
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 69 2e-11
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activa... 69 2e-11
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 69 2e-11
AB209897-1|BAD93134.1| 924|Homo sapiens LATS, large tumor suppr... 69 2e-11
AB051547-1|BAB21851.2| 2219|Homo sapiens KIAA1760 protein protein. 69 2e-11
AB044546-1|BAB18648.1| 779|Homo sapiens mitogen-activated prote... 69 2e-11
AB028019-1|BAA92381.1| 1046|Homo sapiens large tumor suppressor ... 69 2e-11
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 69 2e-11
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 68 3e-11
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 68 3e-11
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 68 3e-11
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 68 3e-11
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 68 3e-11
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 68 3e-11
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 68 3e-11
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 68 3e-11
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 68 3e-11
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 68 3e-11
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 68 3e-11
AF207547-1|AAF80561.1| 1088|Homo sapiens serine/threonine kinase... 68 3e-11
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 68 4e-11
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 68 4e-11
BC019256-1|AAH19256.1| 501|Homo sapiens CaM kinase-like vesicle... 68 4e-11
BC017363-1|AAH17363.1| 501|Homo sapiens CaM kinase-like vesicle... 68 4e-11
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 68 4e-11
BC005828-1|AAH05828.1| 501|Homo sapiens CaM kinase-like vesicle... 68 4e-11
BC001921-1|AAH01921.1| 501|Homo sapiens CaM kinase-like vesicle... 68 4e-11
BC000497-1|AAH00497.1| 501|Homo sapiens CaM kinase-like vesicle... 68 4e-11
AK074899-1|BAC11278.1| 470|Homo sapiens protein ( Homo sapiens ... 68 4e-11
AK074856-1|BAC11248.1| 501|Homo sapiens protein ( Homo sapiens ... 68 4e-11
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 68 4e-11
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 67 6e-11
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 67 6e-11
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 67 6e-11
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 67 6e-11
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 67 6e-11
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 67 6e-11
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 67 6e-11
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 67 6e-11
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 67 6e-11
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 67 6e-11
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 67 6e-11
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 67 6e-11
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 67 6e-11
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 67 6e-11
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 67 6e-11
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 67 6e-11
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 67 6e-11
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 67 6e-11
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 67 6e-11
AK075294-1|BAC11528.1| 470|Homo sapiens protein ( Homo sapiens ... 67 6e-11
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 67 6e-11
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 67 6e-11
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 67 8e-11
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 67 8e-11
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 67 8e-11
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 67 8e-11
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 67 8e-11
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 67 8e-11
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 67 8e-11
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 67 8e-11
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 67 8e-11
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 67 8e-11
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 67 8e-11
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 67 8e-11
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 67 8e-11
BC034501-1|AAH34501.1| 616|Homo sapiens homeodomain interacting... 67 8e-11
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 67 8e-11
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 67 8e-11
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 67 8e-11
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 67 8e-11
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 67 8e-11
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 67 8e-11
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 67 8e-11
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 67 8e-11
AK057380-1|BAB71458.1| 541|Homo sapiens protein ( Homo sapiens ... 67 8e-11
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 67 8e-11
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 67 8e-11
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 67 8e-11
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 67 8e-11
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 67 8e-11
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 66 1e-10
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 66 1e-10
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 66 1e-10
AY358353-1|AAQ88719.1| 364|Homo sapiens HSA250839 protein. 66 1e-10
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 66 1e-10
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 66 1e-10
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 66 1e-10
AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-... 66 1e-10
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 66 1e-10
Z95152-5|CAO03649.1| 360|Homo sapiens mitogen-activated protein... 66 1e-10
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 66 1e-10
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 66 1e-10
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 66 1e-10
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 66 1e-10
L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein pr... 66 1e-10
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 66 1e-10
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 66 1e-10
CR533508-1|CAG38539.1| 473|Homo sapiens MGC8407 protein. 66 1e-10
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 66 1e-10
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 66 1e-10
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 66 1e-10
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 66 1e-10
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 66 1e-10
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 66 1e-10
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 66 1e-10
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 66 1e-10
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 66 1e-10
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 66 1e-10
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 66 1e-10
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 66 1e-10
AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated ... 66 1e-10
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 66 1e-10
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 66 1e-10
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 66 1e-10
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 66 1e-10
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 66 1e-10
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 66 1e-10
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 66 1e-10
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 66 1e-10
AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced var... 66 1e-10
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 66 1e-10
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 66 2e-10
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 66 2e-10
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 66 2e-10
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 66 2e-10
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 66 2e-10
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 66 2e-10
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 66 2e-10
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 66 2e-10
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 66 2e-10
AK123061-1|BAC85527.1| 712|Homo sapiens (LGR6) mRNA. protein. 66 2e-10
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 66 2e-10
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 66 2e-10
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 66 2e-10
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 66 2e-10
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 66 2e-10
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 65 2e-10
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 65 2e-10
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 65 2e-10
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 65 2e-10
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 65 2e-10
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 65 2e-10
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 65 2e-10
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 65 2e-10
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 65 2e-10
>AB004884-1|BAA20561.1| 719|Homo sapiens PKU-alpha protein.
Length = 719
Score = 377 bits (928), Expect = e-104
Identities = 167/231 (72%), Positives = 199/231 (86%)
Frame = +3
Query: 36 SMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQH 215
++T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRIHNED S+F H
Sbjct: 343 TLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDH 402
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P L++RYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK+W+++KK NY KHA REY
Sbjct: 403 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREY 462
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
IHK LDHPRIVKLYD F +D +SFCTVLEYC G+DLDFYLKQHK I E+EARSI+MQ+V
Sbjct: 463 RIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLISEKEARSIIMQIV 522
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYN 728
+ALKYLNEIKPP+IHYDLKPGNILL G CGEIKITDFGLS++MD+++YN
Sbjct: 523 NALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYN 573
>AF162667-1|AAF03095.1| 749|Homo sapiens tousled-like kinase 2
protein.
Length = 749
Score = 376 bits (925), Expect = e-104
Identities = 166/231 (71%), Positives = 199/231 (86%)
Frame = +3
Query: 36 SMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQH 215
++T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRIHNED S+F H
Sbjct: 373 TLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDH 432
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P L++RYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK+W+++KK NY KHA REY
Sbjct: 433 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREY 492
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
IHK LDHPRIVKLYD F +D +SFCTVLEYC G+DLDFYLKQHK + E+EARSI+MQ+V
Sbjct: 493 RIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIV 552
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYN 728
+ALKYLNEIKPP+IHYDLKPGNILL G CGEIKITDFGLS++MD+++YN
Sbjct: 553 NALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYN 603
>BC044925-1|AAH44925.2| 830|Homo sapiens TLK2 protein protein.
Length = 830
Score = 376 bits (924), Expect = e-104
Identities = 166/230 (72%), Positives = 198/230 (86%)
Frame = +3
Query: 39 MTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQHP 218
+T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRIHNED S+F HP
Sbjct: 455 LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHP 514
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYN 398
L++RYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK+W+++KK NY KHA REY
Sbjct: 515 TLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYR 574
Query: 399 IHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVS 578
IHK LDHPRIVKLYD F +D +SFCTVLEYC G+DLDFYLKQHK + E+EARSI+MQ+V+
Sbjct: 575 IHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVN 634
Query: 579 ALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYN 728
ALKYLNEIKPP+IHYDLKPGNILL G CGEIKITDFGLS++MD+++YN
Sbjct: 635 ALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYN 684
>AB004885-1|BAA20562.1| 787|Homo sapiens PKU-beta protein.
Length = 787
Score = 376 bits (924), Expect = e-104
Identities = 168/241 (69%), Positives = 201/241 (83%)
Frame = +3
Query: 12 FLKPDPLPSMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNE 191
F++P+ +T EY+E +EI KLR LKKE+A +Q E+E+LER RNLHIRELKRIHNE
Sbjct: 403 FVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAGIQAELERLERVRNLHIRELKRIHNE 462
Query: 192 DQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANY 371
D S+F HP L+ERYLLL LLG+GGFSEV KAFDL EQRY A K+HQLNK W+++KK NY
Sbjct: 463 DNSQFKDHPTLNERYLLLHLLGRGGFSEVDKAFDLSEQRYAAVKIHQLNKSWRDEKKENY 522
Query: 372 IKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREA 551
KHA REY IHK LDHPRIVKLYD F +D ++FCTVLEYC G+DLDFYLKQHK + E+EA
Sbjct: 523 HKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEA 582
Query: 552 RSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNP 731
RSIVMQ+V+AL+YLNEIKPP+IHYDLKPGNILL +G CGEIKITDFGLS++MD+++Y
Sbjct: 583 RSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGV 642
Query: 732 D 734
D
Sbjct: 643 D 643
>D50927-1|BAA09486.2| 801|Homo sapiens KIAA0137 protein protein.
Length = 801
Score = 374 bits (921), Expect = e-103
Identities = 167/241 (69%), Positives = 203/241 (84%)
Frame = +3
Query: 12 FLKPDPLPSMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNE 191
F++P+ +T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRI+NE
Sbjct: 417 FVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNE 476
Query: 192 DQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANY 371
D S+F HP L+ERYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK W+++KK NY
Sbjct: 477 DNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENY 536
Query: 372 IKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREA 551
KHA REY IHK LDHPRIVKLYD F +D ++FCTVLEYC G+DLDFYLKQHK + E+EA
Sbjct: 537 HKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEA 596
Query: 552 RSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNP 731
RSIVMQ+V+AL+YLNEIKPP+IHYDLKPGNILL +G CGEIKITDFGLS++MD+++Y
Sbjct: 597 RSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGV 656
Query: 732 D 734
D
Sbjct: 657 D 657
>BC032657-1|AAH32657.1| 766|Homo sapiens tousled-like kinase 1
protein.
Length = 766
Score = 374 bits (921), Expect = e-103
Identities = 167/241 (69%), Positives = 203/241 (84%)
Frame = +3
Query: 12 FLKPDPLPSMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNE 191
F++P+ +T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRI+NE
Sbjct: 382 FVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNE 441
Query: 192 DQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANY 371
D S+F HP L+ERYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK W+++KK NY
Sbjct: 442 DNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENY 501
Query: 372 IKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREA 551
KHA REY IHK LDHPRIVKLYD F +D ++FCTVLEYC G+DLDFYLKQHK + E+EA
Sbjct: 502 HKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEA 561
Query: 552 RSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNP 731
RSIVMQ+V+AL+YLNEIKPP+IHYDLKPGNILL +G CGEIKITDFGLS++MD+++Y
Sbjct: 562 RSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGV 621
Query: 732 D 734
D
Sbjct: 622 D 622
>AF246219-1|AAF71263.1| 549|Homo sapiens SNARE protein kinase SNAK
protein.
Length = 549
Score = 374 bits (921), Expect = e-103
Identities = 167/241 (69%), Positives = 203/241 (84%)
Frame = +3
Query: 12 FLKPDPLPSMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNE 191
F++P+ +T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRI+NE
Sbjct: 165 FVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNE 224
Query: 192 DQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANY 371
D S+F HP L+ERYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK W+++KK NY
Sbjct: 225 DNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENY 284
Query: 372 IKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREA 551
KHA REY IHK LDHPRIVKLYD F +D ++FCTVLEYC G+DLDFYLKQHK + E+EA
Sbjct: 285 HKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEA 344
Query: 552 RSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNP 731
RSIVMQ+V+AL+YLNEIKPP+IHYDLKPGNILL +G CGEIKITDFGLS++MD+++Y
Sbjct: 345 RSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGV 404
Query: 732 D 734
D
Sbjct: 405 D 405
>AF162666-1|AAF03094.1| 718|Homo sapiens tousled-like kinase 1
protein.
Length = 718
Score = 374 bits (921), Expect = e-103
Identities = 167/241 (69%), Positives = 203/241 (84%)
Frame = +3
Query: 12 FLKPDPLPSMTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNE 191
F++P+ +T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRI+NE
Sbjct: 334 FVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNE 393
Query: 192 DQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANY 371
D S+F HP L+ERYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK W+++KK NY
Sbjct: 394 DNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENY 453
Query: 372 IKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREA 551
KHA REY IHK LDHPRIVKLYD F +D ++FCTVLEYC G+DLDFYLKQHK + E+EA
Sbjct: 454 HKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEA 513
Query: 552 RSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNP 731
RSIVMQ+V+AL+YLNEIKPP+IHYDLKPGNILL +G CGEIKITDFGLS++MD+++Y
Sbjct: 514 RSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGV 573
Query: 732 D 734
D
Sbjct: 574 D 574
>AC010092-1|AAY15077.1| 376|Homo sapiens unknown protein.
Length = 376
Score = 371 bits (913), Expect = e-102
Identities = 165/232 (71%), Positives = 198/232 (85%)
Frame = +3
Query: 39 MTYQEYYEADEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQHP 218
+T EY+E +EI KLR LKKE+A++Q E+E+LER RNLHIRELKRI+NED S+F HP
Sbjct: 1 LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHP 60
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYN 398
L+ERYLLL LLG+GGFSEV+KAFDL EQRY A K+HQLNK W+++KK NY KHA REY
Sbjct: 61 TLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYR 120
Query: 399 IHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVS 578
IHK LDHPRIVKLYD F +D ++FCTVLEYC G+DLDFYLKQHK + E+EARSIVMQ+V+
Sbjct: 121 IHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVN 180
Query: 579 ALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPD 734
AL+YLNEIKPP+IHYDLKPGNILL +G CGEIKITDFGLS++MD+++Y D
Sbjct: 181 ALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD 232
>Z25421-1|CAA80908.1| 127|Homo sapiens protein-serine/threonine
kinase protein.
Length = 127
Score = 149 bits (362), Expect = 8e-36
Identities = 63/85 (74%), Positives = 77/85 (90%)
Frame = +3
Query: 480 LEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEG 659
+EYC G+DLDFYLKQHK + E+EARSIVMQ+V+AL+YLNEIKPP+IHYDLKPGNILL +G
Sbjct: 4 MEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDG 63
Query: 660 NVCGEIKITDFGLSQVMDEENYNPD 734
CGEIKITDFGLS++MD+++Y D
Sbjct: 64 TACGEIKITDFGLSKIMDDDSYGVD 88
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 95.9 bits (228), Expect = 1e-19
Identities = 61/168 (36%), Positives = 94/168 (55%)
Frame = +3
Query: 222 LSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNI 401
L RY L LGKG + +V KA +E + + KD +D++ + H RE I
Sbjct: 49 LRHRYEFLETLGKGTYGKVKKA---RESSGRLVAIKSIRKDKIKDEQD--LMHIRREIEI 103
Query: 402 HKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSA 581
+L+HP I+ +++VFE + + V+EY + DL Y+ + + + EREAR Q+VSA
Sbjct: 104 MSSLNHPHIIAIHEVFE-NSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSA 162
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Y ++ + V+H DLK NILL + N G IKI DFGLS + + +
Sbjct: 163 VHYCHQNR--VVHRDLKLENILL-DAN--GNIKIADFGLSNLYHQGKF 205
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 95.9 bits (228), Expect = 1e-19
Identities = 61/168 (36%), Positives = 94/168 (55%)
Frame = +3
Query: 222 LSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNI 401
L RY L LGKG + +V KA +E + + KD +D++ + H RE I
Sbjct: 49 LRHRYEFLETLGKGTYGKVKKA---RESSGRLVAIKSIRKDKIKDEQD--LMHIRREIEI 103
Query: 402 HKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSA 581
+L+HP I+ +++VFE + + V+EY + DL Y+ + + + EREAR Q+VSA
Sbjct: 104 MSSLNHPHIIAIHEVFE-NSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSA 162
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Y ++ + V+H DLK NILL + N G IKI DFGLS + + +
Sbjct: 163 VHYCHQNR--VVHRDLKLENILL-DAN--GNIKIADFGLSNLYHQGKF 205
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 94.3 bits (224), Expect = 4e-19
Identities = 57/168 (33%), Positives = 87/168 (51%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
SR P +RY +LGKGGF++ ++ DL + A K+ ++ K ++ K
Sbjct: 70 SRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDK 129
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
E +H+ L H +V+ Y FE D + +LEYC+ + LK K + E E R
Sbjct: 130 ----EIELHRILHHKHVVQFYHYFE-DKENIYILLEYCSRRSMAHILKARKVLTEPEVRY 184
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+ Q+VS LKYL+E ++H DLK GN + E E+K+ DFGL+
Sbjct: 185 YLRQIVSGLKYLHE--QEILHRDLKLGNFFINEAM---ELKVGDFGLA 227
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 94.3 bits (224), Expect = 4e-19
Identities = 57/168 (33%), Positives = 87/168 (51%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
SR P +RY +LGKGGF++ ++ DL + A K+ ++ K ++ K
Sbjct: 63 SRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDK 122
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
E +H+ L H +V+ Y FE D + +LEYC+ + LK K + E E R
Sbjct: 123 ----EIELHRILHHKHVVQFYHYFE-DKENIYILLEYCSRRSMAHILKARKVLTEPEVRY 177
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+ Q+VS LKYL+E ++H DLK GN + E E+K+ DFGL+
Sbjct: 178 YLRQIVSGLKYLHE--QEILHRDLKLGNFFINEAM---ELKVGDFGLA 220
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 94.3 bits (224), Expect = 4e-19
Identities = 57/168 (33%), Positives = 87/168 (51%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
SR P +RY +LGKGGF++ ++ DL + A K+ ++ K ++ K
Sbjct: 70 SRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDK 129
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
E +H+ L H +V+ Y FE D + +LEYC+ + LK K + E E R
Sbjct: 130 ----EIELHRILHHKHVVQFYHYFE-DKENIYILLEYCSRRSMAHILKARKVLTEPEVRY 184
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+ Q+VS LKYL+E ++H DLK GN + E E+K+ DFGL+
Sbjct: 185 YLRQIVSGLKYLHE--QEILHRDLKLGNFFINEAM---ELKVGDFGLA 227
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 94.3 bits (224), Expect = 4e-19
Identities = 57/168 (33%), Positives = 87/168 (51%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
SR P +RY +LGKGGF++ ++ DL + A K+ ++ K ++ K
Sbjct: 70 SRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDK 129
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
E +H+ L H +V+ Y FE D + +LEYC+ + LK K + E E R
Sbjct: 130 ----EIELHRILHHKHVVQFYHYFE-DKENIYILLEYCSRRSMAHILKARKVLTEPEVRY 184
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+ Q+VS LKYL+E ++H DLK GN + E E+K+ DFGL+
Sbjct: 185 YLRQIVSGLKYLHE--QEILHRDLKLGNFFINEAM---ELKVGDFGLA 227
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 94.3 bits (224), Expect = 4e-19
Identities = 60/168 (35%), Positives = 93/168 (55%)
Frame = +3
Query: 222 LSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNI 401
L RY L LGKG + +V +A + R A K + KD +D++ + H RE I
Sbjct: 88 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIK--SIRKDKIKDEQD--MVHIRREIEI 143
Query: 402 HKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSA 581
+L+HP I+ +Y+VFE + + ++EY + +L Y+ + + + ERE R Q+VSA
Sbjct: 144 MSSLNHPHIISIYEVFE-NKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSA 202
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Y + K V+H DLK NILL + C IKI DFGLS + ++ +
Sbjct: 203 VHYCH--KNGVVHRDLKLENILLDDN--C-NIKIADFGLSNLYQKDKF 245
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 89.4 bits (212), Expect = 1e-17
Identities = 57/165 (34%), Positives = 92/165 (55%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
+RY + +GKGGF+ V++ ++ + A KV + K K Y++ + E IH+
Sbjct: 37 DRYRVGKQIGKGGFAIVYELTSIRTGKKYAGKV--VEKAGLT--KPKYLEKFMSEIRIHQ 92
Query: 408 ALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALK 587
+LDHP I K+Y FE D +LE C+ L L+ + + E E + ++Q++ A+
Sbjct: 93 SLDHPHICKMYKHFE-DNRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVS 151
Query: 588 YLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
YL+ K +IH DLK GNI L E N+ E+K+ D GL+ ++E N
Sbjct: 152 YLH--KRCIIHRDLKLGNIFLDE-NL--EVKVGDLGLAAQLNEPN 191
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 87.8 bits (208), Expect = 4e-17
Identities = 60/175 (34%), Positives = 91/175 (52%)
Frame = +3
Query: 177 RIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKED 356
R N S + P + Y LL +GKG F++V A + R A K+ K
Sbjct: 38 RCRNSIASCADEQPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIID-----KTQ 91
Query: 357 KKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTI 536
++ RE I K L+HP IVKL++V E + + ++EY +G ++ YL H +
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-IMEYASGGEVFDYLVAHGRM 150
Query: 537 PEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
E+EARS Q+VSA++Y ++ + ++H DLK N+LL + IKI DFG S
Sbjct: 151 KEKEARSKFRQIVSAVQYCHQKR--IVHRDLKAENLLL---DADMNIKIADFGFS 200
>BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 87.8 bits (208), Expect = 4e-17
Identities = 56/165 (33%), Positives = 93/165 (56%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P + ++L LG G ++ V+KA+ K+ R + + K K KA+ +++ L E
Sbjct: 8 PPRLDGFILTERLGSGTYATVYKAYAKKDTREVVA-IKCVAK--KSLNKAS-VENLLTEI 63
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
I K + HP IV+L D F+ D ++ ++E+C G DL ++ + +PE+ AR + Q+
Sbjct: 64 EILKGIRHPHIVQLKD-FQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLA 122
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
SAL++L+E + H DLKP NILL+ +K+ DFG +Q M
Sbjct: 123 SALQFLHERN--ISHLDLKPQNILLSSLEK-PHLKLADFGFAQHM 164
>BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 87.8 bits (208), Expect = 4e-17
Identities = 56/165 (33%), Positives = 93/165 (56%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P + ++L LG G ++ V+KA+ K+ R + + K K KA+ +++ L E
Sbjct: 8 PPRLDGFILTERLGSGTYATVYKAYAKKDTREVVA-IKCVAK--KSLNKAS-VENLLTEI 63
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
I K + HP IV+L D F+ D ++ ++E+C G DL ++ + +PE+ AR + Q+
Sbjct: 64 EILKGIRHPHIVQLKD-FQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLA 122
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
SAL++L+E + H DLKP NILL+ +K+ DFG +Q M
Sbjct: 123 SALQFLHERN--ISHLDLKPQNILLSSLEK-PHLKLADFGFAQHM 164
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 87.8 bits (208), Expect = 4e-17
Identities = 60/175 (34%), Positives = 91/175 (52%)
Frame = +3
Query: 177 RIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKED 356
R N S + P + Y LL +GKG F++V A + R A K+ K
Sbjct: 38 RCRNSIASCADEQPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIID-----KTQ 91
Query: 357 KKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTI 536
++ RE I K L+HP IVKL++V E + + ++EY +G ++ YL H +
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-IMEYASGGEVFDYLVAHGRM 150
Query: 537 PEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
E+EARS Q+VSA++Y ++ + ++H DLK N+LL + IKI DFG S
Sbjct: 151 KEKEARSKFRQIVSAVQYCHQKR--IVHRDLKAENLLL---DADMNIKIADFGFS 200
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 87.8 bits (208), Expect = 4e-17
Identities = 60/175 (34%), Positives = 91/175 (52%)
Frame = +3
Query: 177 RIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKED 356
R N S + P + Y LL +GKG F++V A + R A K+ K
Sbjct: 38 RCRNSIASCADEQPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIID-----KTQ 91
Query: 357 KKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTI 536
++ RE I K L+HP IVKL++V E + + ++EY +G ++ YL H +
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-IMEYASGGEVFDYLVAHGRM 150
Query: 537 PEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
E+EARS Q+VSA++Y ++ + ++H DLK N+LL + IKI DFG S
Sbjct: 151 KEKEARSKFRQIVSAVQYCHQKR--IVHRDLKAENLLL---DADMNIKIADFGFS 200
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 87.0 bits (206), Expect = 7e-17
Identities = 60/179 (33%), Positives = 94/179 (52%)
Frame = +3
Query: 165 RELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKD 344
+ + R N S + P + Y L +GKG F++V A + R A K+
Sbjct: 38 QNIPRCRNSITSATDEQPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIID---- 92
Query: 345 WKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQ 524
K ++ RE I K L+HP IVKL++V E + + V+EY +G ++ YL
Sbjct: 93 -KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVA 150
Query: 525 HKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
H + E+EAR+ Q+VSA++Y ++ ++H DLK N+LL +G++ IKI DFG S
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQ--KYIVHRDLKAENLLL-DGDM--NIKIADFGFS 204
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 87.0 bits (206), Expect = 7e-17
Identities = 60/179 (33%), Positives = 94/179 (52%)
Frame = +3
Query: 165 RELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKD 344
+ + R N S + P + Y L +GKG F++V A + R A K+
Sbjct: 38 QNIPRCRNSITSATDEQPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIID---- 92
Query: 345 WKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQ 524
K ++ RE I K L+HP IVKL++V E + + V+EY +G ++ YL
Sbjct: 93 -KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVA 150
Query: 525 HKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
H + E+EAR+ Q+VSA++Y ++ ++H DLK N+LL +G++ IKI DFG S
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQ--KYIVHRDLKAENLLL-DGDM--NIKIADFGFS 204
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 87.0 bits (206), Expect = 7e-17
Identities = 60/179 (33%), Positives = 94/179 (52%)
Frame = +3
Query: 165 RELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKD 344
+ + R N S + P + Y L +GKG F++V A + R A K+
Sbjct: 38 QNIPRCRNSITSATDEQPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIID---- 92
Query: 345 WKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQ 524
K ++ RE I K L+HP IVKL++V E + + V+EY +G ++ YL
Sbjct: 93 -KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVA 150
Query: 525 HKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
H + E+EAR+ Q+VSA++Y ++ ++H DLK N+LL +G++ IKI DFG S
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQ--KYIVHRDLKAENLLL-DGDM--NIKIADFGFS 204
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 87.0 bits (206), Expect = 7e-17
Identities = 60/179 (33%), Positives = 94/179 (52%)
Frame = +3
Query: 165 RELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKD 344
+ + R N S + P + Y L +GKG F++V A + R A K+
Sbjct: 38 QNIPRCRNSITSATDEQPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIID---- 92
Query: 345 WKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQ 524
K ++ RE I K L+HP IVKL++V E + + V+EY +G ++ YL
Sbjct: 93 -KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVA 150
Query: 525 HKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
H + E+EAR+ Q+VSA++Y ++ ++H DLK N+LL +G++ IKI DFG S
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQ--KYIVHRDLKAENLLL-DGDM--NIKIADFGFS 204
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 86.6 bits (205), Expect = 9e-17
Identities = 58/167 (34%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 204 FSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYI-KH 380
F H + + LG+G F++V + + A KV D K KK Y+ K+
Sbjct: 52 FQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVI----DKKRAKKDTYVTKN 107
Query: 381 ALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSI 560
RE I + + HP I +L D+ E + NS+ V+E C G +L + + K + E EAR
Sbjct: 108 LRREGQIQQMIRHPNITQLLDILETE-NSYYLVMELCPGGNLMHKIYEKKRLEESEARRY 166
Query: 561 VMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+ Q++SA+++L+ + V+H DLK N+LL E N IK+ DFGLS
Sbjct: 167 IRQLISAVEHLH--RAGVVHRDLKIENLLLDEDN---NIKLIDFGLS 208
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 86.6 bits (205), Expect = 9e-17
Identities = 60/175 (34%), Positives = 90/175 (51%)
Frame = +3
Query: 177 RIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKED 356
R N S + P + Y LL +GKG F++V A + R A K+ K
Sbjct: 38 RCRNSIASCADEQPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIID-----KTQ 91
Query: 357 KKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTI 536
++ RE I K L+HP IVKL++V E + + ++EY +G + YL H +
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYL-IMEYASGGKVFDYLVAHGRM 150
Query: 537 PEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
E+EARS Q+VSA++Y ++ + ++H DLK N+LL + IKI DFG S
Sbjct: 151 KEKEARSKFRQIVSAVQYCHQKR--IVHRDLKAENLLL---DADMNIKIADFGFS 200
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/175 (34%), Positives = 89/175 (50%)
Frame = +3
Query: 177 RIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKED 356
R N S + P + Y LL +GKG F++V A + R A K+ K
Sbjct: 38 RCRNSIASCADEQPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIID-----KTQ 91
Query: 357 KKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTI 536
++ RE I K L+HP IVKL++V E + ++EY +G + YL H +
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETQKTLYL-IMEYASGGKVFDYLVAHGRM 150
Query: 537 PEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
E+EARS Q+VSA++Y ++ + ++H DLK N+LL + IKI DFG S
Sbjct: 151 KEKEARSKFRQIVSAVQYCHQKR--IVHRDLKAENLLL---DADMNIKIADFGFS 200
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 85.0 bits (201), Expect = 3e-16
Identities = 57/152 (37%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LLGKG F+ V++A E +T +V D K KA ++ E IH L HP I
Sbjct: 17 LLGKGSFAGVYRA----ESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPSI 72
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQH-KTIPEREARSIVMQVVSALKYLNEIK 605
++LY+ FE D N VLE C+ +++ YLK K E EAR + Q+++ + YL+
Sbjct: 73 LELYNYFE-DSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH--S 129
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++H DL N+LLT IKI DFGL+
Sbjct: 130 HGILHRDLTLSNLLLTRNM---NIKIADFGLA 158
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/156 (35%), Positives = 86/156 (55%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + + A K+ K ++ ++ RE I K L
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIID-----KTQLNSSSLQKLFREVRIMKVL 74
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY +G ++ YL H + E+EAR+ Q+VSA++Y
Sbjct: 75 NHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 133
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL + IKI DFG S
Sbjct: 134 HQ--KFIVHRDLKAENLLL---DADMNIKIADFGFS 164
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/156 (35%), Positives = 86/156 (55%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + + A K+ K ++ ++ RE I K L
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIID-----KTQLNSSSLQKLFREVRIMKVL 74
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY +G ++ YL H + E+EAR+ Q+VSA++Y
Sbjct: 75 NHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 133
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL + IKI DFG S
Sbjct: 134 HQ--KFIVHRDLKAENLLL---DADMNIKIADFGFS 164
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/156 (35%), Positives = 86/156 (55%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + + A K+ K ++ ++ RE I K L
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIID-----KTQLNSSSLQKLFREVRIMKVL 107
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY +G ++ YL H + E+EAR+ Q+VSA++Y
Sbjct: 108 NHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 166
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL + IKI DFG S
Sbjct: 167 HQ--KFIVHRDLKAENLLL---DADMNIKIADFGFS 197
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 85.0 bits (201), Expect = 3e-16
Identities = 57/152 (37%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LLGKG F+ V++A E +T +V D K KA ++ E IH L HP I
Sbjct: 17 LLGKGSFAGVYRA----ESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSI 72
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQH-KTIPEREARSIVMQVVSALKYLNEIK 605
++LY+ FE D N VLE C+ +++ YLK K E EAR + Q+++ + YL+
Sbjct: 73 LELYNYFE-DSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH--S 129
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++H DL N+LLT IKI DFGL+
Sbjct: 130 HGILHRDLTLSNLLLTRNM---NIKIADFGLA 158
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/156 (35%), Positives = 86/156 (55%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + + A K+ K ++ ++ RE I K L
Sbjct: 43 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIID-----KTQLNSSSLQKLFREVRIMKVL 97
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY +G ++ YL H + E+EAR+ Q+VSA++Y
Sbjct: 98 NHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 156
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL + IKI DFG S
Sbjct: 157 HQ--KFIVHRDLKAENLLL---DADMNIKIADFGFS 187
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/156 (35%), Positives = 86/156 (55%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + + A K+ K ++ ++ RE I K L
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIID-----KTQLNSSSLQKLFREVRIMKVL 74
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY +G ++ YL H + E+EAR+ Q+VSA++Y
Sbjct: 75 NHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 133
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL + IKI DFG S
Sbjct: 134 HQ--KFIVHRDLKAENLLL---DADMNIKIADFGFS 164
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/156 (35%), Positives = 86/156 (55%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + + A K+ K ++ ++ RE I K L
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIID-----KTQLNSSSLQKLFREVRIMKVL 107
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY +G ++ YL H + E+EAR+ Q+VSA++Y
Sbjct: 108 NHPNIVKLFEVIETEKTLYL-VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 166
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL + IKI DFG S
Sbjct: 167 HQ--KFIVHRDLKAENLLL---DADMNIKIADFGFS 197
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 84.6 bits (200), Expect = 4e-16
Identities = 57/157 (36%), Positives = 84/157 (53%), Gaps = 1/157 (0%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + R A K+ K + ++ RE I K L
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIID-----KTQLNPSSLQKLFREVRIMKGL 113
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY + ++ YL H + E+EAR+ Q+VSA+ Y
Sbjct: 114 NHPNIVKLFEVIETEKTLYL-VMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYC 172
Query: 594 NEIKPPVIHYDLKPGNILL-TEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL E N IKI DFG S
Sbjct: 173 HQ--KNIVHRDLKAENLLLDAEAN----IKIADFGFS 203
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 84.6 bits (200), Expect = 4e-16
Identities = 57/157 (36%), Positives = 84/157 (53%), Gaps = 1/157 (0%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + R A K+ K + ++ RE I K L
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIID-----KTQLNPSSLQKLFREVRIMKGL 113
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY + ++ YL H + E+EAR+ Q+VSA+ Y
Sbjct: 114 NHPNIVKLFEVIETEKTLYL-VMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYC 172
Query: 594 NEIKPPVIHYDLKPGNILL-TEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL E N IKI DFG S
Sbjct: 173 HQ--KNIVHRDLKAENLLLDAEAN----IKIADFGFS 203
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 84.6 bits (200), Expect = 4e-16
Identities = 57/157 (36%), Positives = 84/157 (53%), Gaps = 1/157 (0%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + R A K+ K + ++ RE I K L
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIID-----KTQLNPSSLQKLFREVRIMKGL 113
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY + ++ YL H + E+EAR+ Q+VSA+ Y
Sbjct: 114 NHPNIVKLFEVIETEKTLYL-VMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYC 172
Query: 594 NEIKPPVIHYDLKPGNILL-TEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL E N IKI DFG S
Sbjct: 173 HQ--KNIVHRDLKAENLLLDAEAN----IKIADFGFS 203
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 84.6 bits (200), Expect = 4e-16
Identities = 57/157 (36%), Positives = 84/157 (53%), Gaps = 1/157 (0%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG F++V A + R A K+ K + ++ RE I K L
Sbjct: 60 YRLLRTIGKGNFAKVKLARHILTGREVAIKIID-----KTQLNPSSLQKLFREVRIMKGL 114
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY + ++ YL H + E+EAR+ Q+VSA+ Y
Sbjct: 115 NHPNIVKLFEVIETEKTLYL-VMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYC 173
Query: 594 NEIKPPVIHYDLKPGNILL-TEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL E N IKI DFG S
Sbjct: 174 HQ--KNIVHRDLKAENLLLDAEAN----IKIADFGFS 204
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 84.2 bits (199), Expect = 5e-16
Identities = 56/161 (34%), Positives = 89/161 (55%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
E+Y +L ++G+G F V+K ++Y+A +V L K + +++ RE I +
Sbjct: 2 EKYHVLEMIGEGSFGRVYKG----RRKYSA-QVVALKFIPKLGRSEKELRNLQREIEIMR 56
Query: 408 ALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALK 587
L HP IV + D FE D V +Y G +L L+ +PE + ++I Q+VSAL
Sbjct: 57 GLRHPNIVHMLDSFETD-KEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALY 114
Query: 588 YLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
YL+ + ++H D+KP NILL +G G IK+ DFG ++ M
Sbjct: 115 YLHSHR--ILHRDMKPQNILLAKG---GGIKLCDFGFARAM 150
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 84.2 bits (199), Expect = 5e-16
Identities = 56/161 (34%), Positives = 89/161 (55%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
E+Y +L ++G+G F V+K ++Y+A +V L K + +++ RE I +
Sbjct: 2 EKYHVLEMIGEGSFGRVYKG----RRKYSA-QVVALKFIPKLGRSEKELRNLQREIEIMR 56
Query: 408 ALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALK 587
L HP IV + D FE D V +Y G +L L+ +PE + ++I Q+VSAL
Sbjct: 57 GLRHPNIVHMLDSFETD-KEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALY 114
Query: 588 YLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
YL+ + ++H D+KP NILL +G G IK+ DFG ++ M
Sbjct: 115 YLHSHR--ILHRDMKPQNILLAKG---GGIKLCDFGFARAM 150
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 84.2 bits (199), Expect = 5e-16
Identities = 56/161 (34%), Positives = 89/161 (55%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
E+Y +L ++G+G F V+K ++Y+A +V L K + +++ RE I +
Sbjct: 19 EKYHVLEMIGEGSFGRVYKG----RRKYSA-QVVALKFIPKLGRSEKELRNLQREIEIMR 73
Query: 408 ALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALK 587
L HP IV + D FE D V +Y G +L L+ +PE + ++I Q+VSAL
Sbjct: 74 GLRHPNIVHMLDSFETD-KEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALY 131
Query: 588 YLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
YL+ + ++H D+KP NILL +G G IK+ DFG ++ M
Sbjct: 132 YLHSHR--ILHRDMKPQNILLAKG---GGIKLCDFGFARAM 167
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 83.8 bits (198), Expect = 6e-16
Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 1/152 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LLGKG F+ V++A + A K+ D K KA ++ E IH L HP I
Sbjct: 17 LLGKGSFAGVYRAESIHSGLEVAIKMI----DKKAMYKAGMVQRVQNEVKIHCQLKHPSI 72
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQH-KTIPEREARSIVMQVVSALKYLNEIK 605
++LY+ FE D N VLE C+ +++ YLK K E EAR + Q+++ + YL+
Sbjct: 73 LELYNYFE-DSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH--S 129
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++H DL N+LLT IKI DFGL+
Sbjct: 130 HGILHRDLTLSNLLLTRNM---NIKIADFGLA 158
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/184 (32%), Positives = 88/184 (47%)
Frame = +3
Query: 150 RNLHIRELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVH 329
R + L + D R P YL LLGKGGF+ ++A D + A KV
Sbjct: 34 RGPELEMLAGLPTSDPGRLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVI 93
Query: 330 QLNKDWKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLD 509
++ K ++ + L E +H+ L H IV+ FE D ++ LE C+ L
Sbjct: 94 PQSRVAKPHQR----EKILNEIELHRDLQHRHIVRFSHHFE-DADNIYIFLELCSRKSLA 148
Query: 510 FYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITD 689
K T+ E E R + Q++S LKYL++ ++H DLK GN +TE E+K+ D
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQ--RGILHRDLKLGNFFITENM---ELKVGD 203
Query: 690 FGLS 701
FGL+
Sbjct: 204 FGLA 207
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/184 (32%), Positives = 88/184 (47%)
Frame = +3
Query: 150 RNLHIRELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVH 329
R + L + D R P YL LLGKGGF+ ++A D + A KV
Sbjct: 34 RGPELEMLAGLPTSDPGRLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVI 93
Query: 330 QLNKDWKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLD 509
++ K ++ + L E +H+ L H IV+ FE D ++ LE C+ L
Sbjct: 94 PQSRVAKPHQR----EKILNEIELHRDLQHRHIVRFSHHFE-DADNIYIFLELCSRKSLA 148
Query: 510 FYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITD 689
K T+ E E R + Q++S LKYL++ ++H DLK GN +TE E+K+ D
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQ--RGILHRDLKLGNFFITENM---ELKVGD 203
Query: 690 FGLS 701
FGL+
Sbjct: 204 FGLA 207
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/184 (32%), Positives = 88/184 (47%)
Frame = +3
Query: 150 RNLHIRELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVH 329
R + L + D R P YL LLGKGGF+ ++A D + A KV
Sbjct: 34 RGPELEMLAGLPTSDPGRLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVI 93
Query: 330 QLNKDWKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLD 509
++ K ++ + L E +H+ L H IV+ FE D ++ LE C+ L
Sbjct: 94 PQSRVAKPHQR----EKILNEIELHRDLQHRHIVRFSHHFE-DADNIYIFLELCSRKSLA 148
Query: 510 FYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITD 689
K T+ E E R + Q++S LKYL++ ++H DLK GN +TE E+K+ D
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQ--RGILHRDLKLGNFFITENM---ELKVGD 203
Query: 690 FGLS 701
FGL+
Sbjct: 204 FGLA 207
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/184 (32%), Positives = 88/184 (47%)
Frame = +3
Query: 150 RNLHIRELKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVH 329
R + L + D R P YL LLGKGGF+ ++A D + A KV
Sbjct: 34 RGPELEMLAGLPTSDPGRLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVI 93
Query: 330 QLNKDWKEDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLD 509
++ K ++ + L E +H+ L H IV+ FE D ++ LE C+ L
Sbjct: 94 PQSRVVKPHQR----EKILNEIELHRDLQHRHIVRFSHHFE-DADNIYIFLELCSRKSLA 148
Query: 510 FYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITD 689
K T+ E E R + Q++S LKYL++ ++H DLK GN +TE E+K+ D
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQ--RGILHRDLKLGNFFITENM---ELKVGD 203
Query: 690 FGLS 701
FGL+
Sbjct: 204 FGLA 207
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/177 (32%), Positives = 86/177 (48%)
Frame = +3
Query: 171 LKRIHNEDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWK 350
L + D R P YL LLGKGGF+ ++A D + A KV ++ K
Sbjct: 2 LAGLPTSDPGRLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAK 61
Query: 351 EDKKANYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK 530
++ + L E +H+ L H IV+ FE D ++ LE C+ L K
Sbjct: 62 PHQR----EKILNEIELHRDLQHRHIVRFSHHFE-DADNIYIFLELCSRKSLAHIWKARH 116
Query: 531 TIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
T+ E E R + Q++S LKYL++ ++H DLK GN +TE E+K+ DFGL+
Sbjct: 117 TLLEPEVRYYLRQILSGLKYLHQ--RGILHRDLKLGNFFITENM---ELKVGDFGLA 168
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 87 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 142
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 143 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 199
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 200 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 234
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 87 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 142
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 143 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 199
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 200 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 234
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 87 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 142
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 143 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 199
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 200 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 234
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 87 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 142
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 143 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 199
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 200 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 234
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 79 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 134
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 135 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 191
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 192 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 226
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 81.8 bits (193), Expect = 2e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 125 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 180
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 181 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 237
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 238 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 272
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/158 (36%), Positives = 83/158 (52%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 60 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 115
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSAL+YL+
Sbjct: 116 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH--GK 172
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 173 GIIHRDLKPENILLNEDMY---IQITDFGTAKVLSPES 207
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 81.4 bits (192), Expect = 3e-15
Identities = 56/157 (35%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG ++V A + R A K+ K + ++ RE I K L
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIID-----KTQLNPSSLQKLFREVRIMKGL 113
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY + ++ YL H + E+EAR+ Q+VSA+ Y
Sbjct: 114 NHPNIVKLFEVIETEKTLYL-VMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYC 172
Query: 594 NEIKPPVIHYDLKPGNILL-TEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL E N IKI DFG S
Sbjct: 173 HQ--KNIVHRDLKAENLLLDAEAN----IKIADFGFS 203
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 81.4 bits (192), Expect = 3e-15
Identities = 56/157 (35%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y LL +GKG ++V A + R A K+ K + ++ RE I K L
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIID-----KTQLNPSSLQKLFREVRIMKGL 113
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
+HP IVKL++V E + + V+EY + ++ YL H + E+EAR+ Q+VSA+ Y
Sbjct: 114 NHPNIVKLFEVIETEKTLYL-VMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYC 172
Query: 594 NEIKPPVIHYDLKPGNILL-TEGNVCGEIKITDFGLS 701
++ ++H DLK N+LL E N IKI DFG S
Sbjct: 173 HQ--KNIVHRDLKAENLLLDAEAN----IKIADFGFS 203
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 80.2 bits (189), Expect = 8e-15
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL-REY 395
+LS Y L +G+G +S+V +AF K QR A KV K +I+ L RE
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVID-----KMGGPEEFIQRFLPREL 59
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
I + LDH I+++Y++ E C V+E G D+ + +PE A+++ Q+V
Sbjct: 60 QIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMV 119
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
A++Y + V H DLK N LL N +K+TDFG ++V+ + +
Sbjct: 120 EAIRYCHGC--GVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSH 162
>BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein.
Length = 482
Score = 80.2 bits (189), Expect = 8e-15
Identities = 53/168 (31%), Positives = 90/168 (53%), Gaps = 4/168 (2%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYN 398
+++ RY+L LG G F V+ D K +R KV L + + N A E
Sbjct: 24 LIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV--LKEISVGELNPNETVQANLEAQ 81
Query: 399 IHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQH----KTIPEREARSIVM 566
+ LDHP IVK + F ++ ++FC + EYC G DLD ++++ K PE + +
Sbjct: 82 LLSKLDHPAIVKFHASF-VEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFI 140
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
Q++ + Y++E + ++H DLK N+ L + N+ +KI DFG+S+++
Sbjct: 141 QLLLGVDYMHERR--ILHRDLKSKNVFL-KNNL---LKIGDFGVSRLL 182
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 80.2 bits (189), Expect = 8e-15
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL-REY 395
+LS Y L +G+G +S+V +AF K QR A KV K +I+ L RE
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVID-----KMGGPEEFIQRFLPREL 59
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
I + LDH I+++Y++ E C V+E G D+ + +PE A+++ Q+V
Sbjct: 60 QIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMV 119
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
A++Y + V H DLK N LL N +K+TDFG ++V+ + +
Sbjct: 120 EAIRYCHGC--GVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSH 162
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 80.2 bits (189), Expect = 8e-15
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL-REY 395
+LS Y L +G+G +S+V +AF K QR A KV K +I+ L RE
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVID-----KMGGPEEFIQRFLPREL 59
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
I + LDH I+++Y++ E C V+E G D+ + +PE A+++ Q+V
Sbjct: 60 QIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMV 119
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
A++Y + V H DLK N LL N +K+TDFG ++V+ + +
Sbjct: 120 EAIRYCHGC--GVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSH 162
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 80.2 bits (189), Expect = 8e-15
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL-REY 395
+LS Y L +G+G +S+V +AF K QR A KV K +I+ L RE
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVID-----KMGGPEEFIQRFLPREL 59
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
I + LDH I+++Y++ E C V+E G D+ + +PE A+++ Q+V
Sbjct: 60 QIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMV 119
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
A++Y + V H DLK N LL N +K+TDFG ++V+ + +
Sbjct: 120 EAIRYCHGC--GVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSH 162
>AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S
protein.
Length = 470
Score = 80.2 bits (189), Expect = 8e-15
Identities = 53/168 (31%), Positives = 90/168 (53%), Gaps = 4/168 (2%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYN 398
+++ RY+L LG G F V+ D K +R KV L + + N A E
Sbjct: 24 LIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV--LKEISVGELNPNETVQANLEAQ 81
Query: 399 IHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQH----KTIPEREARSIVM 566
+ LDHP IVK + F ++ ++FC + EYC G DLD ++++ K PE + +
Sbjct: 82 LLSKLDHPAIVKFHASF-VEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFI 140
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
Q++ + Y++E + ++H DLK N+ L + N+ +KI DFG+S+++
Sbjct: 141 QLLLGVDYMHERR--ILHRDLKSKNVFL-KNNL---LKIGDFGVSRLL 182
>AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L
protein.
Length = 645
Score = 80.2 bits (189), Expect = 8e-15
Identities = 53/168 (31%), Positives = 90/168 (53%), Gaps = 4/168 (2%)
Frame = +3
Query: 219 VLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYN 398
+++ RY+L LG G F V+ D K +R KV L + + N A E
Sbjct: 24 LIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV--LKEISVGELNPNETVQANLEAQ 81
Query: 399 IHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQH----KTIPEREARSIVM 566
+ LDHP IVK + F ++ ++FC + EYC G DLD ++++ K PE + +
Sbjct: 82 LLSKLDHPAIVKFHASF-VEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFI 140
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
Q++ + Y++E + ++H DLK N+ L + N+ +KI DFG+S+++
Sbjct: 141 QLLLGVDYMHERR--ILHRDLKSKNVFL-KNNL---LKIGDFGVSRLL 182
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 79.8 bits (188), Expect = 1e-14
Identities = 58/163 (35%), Positives = 84/163 (51%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
+H V + L LLGKG F +V + RY A K+ L K+ K + + H L
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI--LKKEVIVAK--DEVAHTLT 197
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E + + HP + L F+ + C V+EY NG +L F+L + + E AR +
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTH-DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAE 256
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+VSAL YL+ K V++ DLK N++L + G IKITDFGL
Sbjct: 257 IVSALDYLHSEK-NVVYRDLKLENLMLDKD---GHIKITDFGL 295
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 79.8 bits (188), Expect = 1e-14
Identities = 55/153 (35%), Positives = 87/153 (56%), Gaps = 1/153 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A + ++ A KV L K ++K KH + E N+ K + H
Sbjct: 98 LKVIGKGSFGKVLLAKRKLDGKFYAVKV--LQKKIVLNRKEQ--KHIMAERNVLLKNVKH 153
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL++ NG +L F+L++ ++ PE AR ++ SAL YL+
Sbjct: 154 PFLVGLHYSFQTTEKLYF-VLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHS 212
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
IK +++ DLKP NILL + G + +TDFGL
Sbjct: 213 IK--IVYRDLKPENILL---DSVGHVVLTDFGL 240
>CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 79.8 bits (188), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 44 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKARW--DCVKEIGLLKQLNHPNII 99
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 100 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 158
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 159 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 193
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 79.8 bits (188), Expect = 1e-14
Identities = 58/163 (35%), Positives = 84/163 (51%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
+H V + L LLGKG F +V + RY A K+ L K+ K + + H L
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI--LKKEVIVAK--DEVAHTLT 197
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E + + HP + L F+ + C V+EY NG +L F+L + + E AR +
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTH-DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAE 256
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+VSAL YL+ K V++ DLK N++L + G IKITDFGL
Sbjct: 257 IVSALDYLHSEK-NVVYRDLKLENLMLDKD---GHIKITDFGL 295
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 79.8 bits (188), Expect = 1e-14
Identities = 55/153 (35%), Positives = 87/153 (56%), Gaps = 1/153 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A + ++ A KV L K ++K KH + E N+ K + H
Sbjct: 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKV--LQKKIVLNRKEQ--KHIMAERNVLLKNVKH 220
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL++ NG +L F+L++ ++ PE AR ++ SAL YL+
Sbjct: 221 PFLVGLHYSFQTTEKLYF-VLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHS 279
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
IK +++ DLKP NILL + G + +TDFGL
Sbjct: 280 IK--IVYRDLKPENILL---DSVGHVVLTDFGL 307
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 79.8 bits (188), Expect = 1e-14
Identities = 58/163 (35%), Positives = 84/163 (51%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
+H V + L LLGKG F +V + RY A K+ L K+ K + + H L
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI--LKKEVIVAK--DEVAHTLT 197
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E + + HP + L F+ + C V+EY NG +L F+L + + E AR +
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTH-DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAE 256
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+VSAL YL+ K V++ DLK N++L + G IKITDFGL
Sbjct: 257 IVSALDYLHSEK-NVVYRDLKLENLMLDKD---GHIKITDFGL 295
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 79.8 bits (188), Expect = 1e-14
Identities = 55/153 (35%), Positives = 87/153 (56%), Gaps = 1/153 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A + ++ A KV L K ++K KH + E N+ K + H
Sbjct: 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKV--LQKKIVLNRKEQ--KHIMAERNVLLKNVKH 220
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL++ NG +L F+L++ ++ PE AR ++ SAL YL+
Sbjct: 221 PFLVGLHYSFQTTEKLYF-VLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHS 279
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
IK +++ DLKP NILL + G + +TDFGL
Sbjct: 280 IK--IVYRDLKPENILL---DSVGHVVLTDFGL 307
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 79.8 bits (188), Expect = 1e-14
Identities = 58/163 (35%), Positives = 84/163 (51%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
+H V + L LLGKG F +V + RY A K+ L K+ K + + H L
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI--LKKEVIVAK--DEVAHTLT 197
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E + + HP + L F+ + C V+EY NG +L F+L + + E AR +
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTH-DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAE 256
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+VSAL YL+ K V++ DLK N++L + G IKITDFGL
Sbjct: 257 IVSALDYLHSEK-NVVYRDLKLENLMLDKD---GHIKITDFGL 295
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 79.8 bits (188), Expect = 1e-14
Identities = 55/153 (35%), Positives = 87/153 (56%), Gaps = 1/153 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A + ++ A KV L K ++K KH + E N+ K + H
Sbjct: 98 LKVIGKGSFGKVLLAKRKLDGKFYAVKV--LQKKIVLNRKEQ--KHIMAERNVLLKNVKH 153
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL++ NG +L F+L++ ++ PE AR ++ SAL YL+
Sbjct: 154 PFLVGLHYSFQTTEKLYF-VLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHS 212
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
IK +++ DLKP NILL + G + +TDFGL
Sbjct: 213 IK--IVYRDLKPENILL---DSVGHVVLTDFGL 240
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 79.4 bits (187), Expect = 1e-14
Identities = 57/212 (26%), Positives = 109/212 (51%), Gaps = 1/212 (0%)
Frame = +3
Query: 66 DEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQHPVLSERYLLL 245
+ ++ + QS++ + A + E + E K N +S + + + + LL
Sbjct: 189 EPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLL 248
Query: 246 MLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDW-KEDKKANYIKHALREYNIHKALDHP 422
++G+G +++V K R A KV + K+ +D+ ++++ ++ +A +HP
Sbjct: 249 RVIGRGSYAKVLLVRLKKTDRIYAMKV--VKKELVNDDEDIDWVQ--TEKHVFEQASNHP 304
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+V L+ F+ + F V+EY NG DL F++++ + +PE AR ++ AL YL+E
Sbjct: 305 FLVGLHSCFQTESRLFF-VIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE- 362
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+I+ DLK N+LL G IK+TD+G+
Sbjct: 363 -RGIIYRDLKLDNVLLDSE---GHIKLTDYGM 390
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 79.4 bits (187), Expect = 1e-14
Identities = 57/212 (26%), Positives = 109/212 (51%), Gaps = 1/212 (0%)
Frame = +3
Query: 66 DEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQHPVLSERYLLL 245
+ ++ + QS++ + A + E + E K N +S + + + + LL
Sbjct: 189 EPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLL 248
Query: 246 MLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDW-KEDKKANYIKHALREYNIHKALDHP 422
++G+G +++V K R A KV + K+ +D+ ++++ ++ +A +HP
Sbjct: 249 RVIGRGSYAKVLLVRLKKTDRIYAMKV--VKKELVNDDEDIDWVQ--TEKHVFEQASNHP 304
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+V L+ F+ + F V+EY NG DL F++++ + +PE AR ++ AL YL+E
Sbjct: 305 FLVGLHSCFQTESRLFF-VIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE- 362
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+I+ DLK N+LL G IK+TD+G+
Sbjct: 363 -RGIIYRDLKLDNVLLDSE---GHIKLTDYGM 390
>CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 44 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 99
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 100 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 158
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 159 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 193
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 250 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 307
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 308 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 365
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 366 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 423
Query: 726 NPDLAWT 746
L T
Sbjct: 424 MRTLCGT 430
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 79.4 bits (187), Expect = 1e-14
Identities = 57/212 (26%), Positives = 109/212 (51%), Gaps = 1/212 (0%)
Frame = +3
Query: 66 DEILKLRQSALKKEDADLQLEMEKLERERNLHIRELKRIHNEDQSRFSQHPVLSERYLLL 245
+ ++ + QS++ + A + E + E K N +S + + + + LL
Sbjct: 189 EPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLL 248
Query: 246 MLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDW-KEDKKANYIKHALREYNIHKALDHP 422
++G+G +++V K R A KV + K+ +D+ ++++ ++ +A +HP
Sbjct: 249 RVIGRGSYAKVLLVRLKKTDRIYAMKV--VKKELVNDDEDIDWVQ--TEKHVFEQASNHP 304
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+V L+ F+ + F V+EY NG DL F++++ + +PE AR ++ AL YL+E
Sbjct: 305 FLVGLHSCFQTESRLFF-VIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE- 362
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+I+ DLK N+LL G IK+TD+G+
Sbjct: 363 -RGIIYRDLKLDNVLLDSE---GHIKLTDYGM 390
>BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 116 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 173
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 174 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 231
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 232 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 289
Query: 726 NPDLAWT 746
L T
Sbjct: 290 MRTLCGT 296
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 250 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 307
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 308 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 365
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 366 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 423
Query: 726 NPDLAWT 746
L T
Sbjct: 424 MRTLCGT 430
>AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL162724-7|CAH70252.1| 222|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 222
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL162724-6|CAH70251.1| 220|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 220
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL162724-5|CAH70250.1| 219|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 219
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL162724-4|CAH70249.1| 207|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 207
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 85 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 140
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 141 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 199
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 200 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 234
>AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL137846-11|CAI10881.1| 222|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 222
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL137846-10|CAI10880.1| 220|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 220
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL137846-9|CAI10879.1| 219|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 219
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL137846-8|CAI10878.1| 207|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 207
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 106
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 107 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 166 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 200
>AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 85 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 140
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 141 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 199
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 200 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 234
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 79.4 bits (187), Expect = 1e-14
Identities = 56/158 (35%), Positives = 82/158 (51%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG+G FS V A +L R A K+ + KE+K + + RE ++ LDHP
Sbjct: 87 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENK----VPYVTRERDVMSRLDHPFF 142
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
VKLY F+ D L Y +L Y+++ + E R ++VSA +YL+
Sbjct: 143 VKLYFTFQ-DDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLH--GK 199
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+IH DLKP NILL E I+ITDFG ++V+ E+
Sbjct: 200 GIIHRDLKPENILLNEDM---HIQITDFGTAKVLSPES 234
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6
protein.
Length = 338
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 76 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 131
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 132 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 190
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 191 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 225
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 79.4 bits (187), Expect = 1e-14
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 1/187 (0%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKA 365
+DQS + + L + Y++ LG G EV AF+ K + A K+ K ++A
Sbjct: 207 DDQSVYPK--ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREA 264
Query: 366 NYIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPER 545
+ + E I K L+HP I+K+ + F D + VLE G +L + +K + E
Sbjct: 265 DPALNVETEIEILKKLNHPCIIKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEA 322
Query: 546 EARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ Q++ A++YL+E +IH DLKP N+LL+ IKITDFG S+++ E +
Sbjct: 323 TCKLYFYQMLLAVQYLHE--NGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL 380
Query: 726 NPDLAWT 746
L T
Sbjct: 381 MRTLCGT 387
>AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-1512
protein.
Length = 306
Score = 79.4 bits (187), Expect = 1e-14
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV+KA L +++ A K Q+ + D KA + ++E + K L+HP I+
Sbjct: 44 IGRGQFSEVYKATCLLDRKTVALKKVQIFE--MMDAKAR--QDCVKEIGLLKQLNHPNII 99
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K D F I+ N VLE + DL ++ KQ + IPER +Q+ SA+++++
Sbjct: 100 KYLDSF-IEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 158
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEE 719
+ V+H D+KP N+ +T G +K+ D GL + E
Sbjct: 159 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGRFFSSE 193
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 79.0 bits (186), Expect = 2e-14
Identities = 58/163 (35%), Positives = 85/163 (52%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
+H V + L LLGKG F +V + K Y A K+ L K+ K + + H L
Sbjct: 80 KHRVTMNEFEYLKLLGKGTFGKVILVKE-KATAYYAMKI--LKKEVIVAK--DEVAHTLT 134
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E + + HP + +L F+ + C V+EY NG +L F+L + + E AR +
Sbjct: 135 ENRVQQNSRHPFLTRLKYSFQTH-DRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAE 193
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
+VSAL YL+ K V++ DLK N++L + G IKITDFGL
Sbjct: 194 IVSALDYLHSEK-NVVYRDLKLENLMLDKD---GHIKITDFGL 232
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 79.0 bits (186), Expect = 2e-14
Identities = 56/141 (39%), Positives = 74/141 (52%), Gaps = 13/141 (9%)
Frame = +3
Query: 327 HQLNKDW----KEDKKANYIKHAL---REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLE 485
H+ DW K K N K + +E I K L H IV LYDV E+ NS V+E
Sbjct: 28 HRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELP-NSVFLVME 86
Query: 486 YCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGN- 662
YCNG DL YL+ T+ E R + Q+ +A++ L+ +IH DLKP NILL+ N
Sbjct: 87 YCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILH--SKGIIHRDLKPQNILLSYANR 144
Query: 663 ----VCG-EIKITDFGLSQVM 710
V G IKI DFG ++ +
Sbjct: 145 RKSSVSGIRIKIADFGFARYL 165
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/156 (34%), Positives = 81/156 (51%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
YL LLGKGGF+ ++A D + A KV ++ K ++ + L E +H+ L
Sbjct: 37 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQR----EKILNEIELHRDL 92
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
H IV+ FE D ++ LE C+ L K T+ E E R + Q++S LKYL
Sbjct: 93 QHRHIVRFSHHFE-DADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYL 151
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
++ ++H DLK GN +TE E+K+ DFGL+
Sbjct: 152 HQ--RGILHRDLKLGNFFITENM---ELKVGDFGLA 182
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 79.0 bits (186), Expect = 2e-14
Identities = 56/141 (39%), Positives = 74/141 (52%), Gaps = 13/141 (9%)
Frame = +3
Query: 327 HQLNKDW----KEDKKANYIKHAL---REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLE 485
H+ DW K K N K + +E I K L H IV LYDV E+ NS V+E
Sbjct: 92 HRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELP-NSVFLVME 150
Query: 486 YCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGN- 662
YCNG DL YL+ T+ E R + Q+ +A++ L+ +IH DLKP NILL+ N
Sbjct: 151 YCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILH--SKGIIHRDLKPQNILLSYANR 208
Query: 663 ----VCG-EIKITDFGLSQVM 710
V G IKI DFG ++ +
Sbjct: 209 RKSSVSGIRIKIADFGFARYL 229
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 78.2 bits (184), Expect = 3e-14
Identities = 54/171 (31%), Positives = 97/171 (56%)
Frame = +3
Query: 201 RFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKH 380
R+ Q + + Y +LG G FSEV A D + Q+ A K + K+ E K+ + +++
Sbjct: 9 RWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAKEALEGKEGS-MEN 65
Query: 381 ALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSI 560
+ +HK + HP IV L D++E G+ + +++ +G +L + + ER+A +
Sbjct: 66 EIAV--LHK-IKHPNIVALDDIYESGGHLYL-IMQLVSGGELFDRIVEKGFYTERDASRL 121
Query: 561 VMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMD 713
+ QV+ A+KYL+++ ++H DLKP N+L + +I I+DFGLS++ D
Sbjct: 122 IFQVLDAVKYLHDLG--IVHRDLKPENLLYYSLDEDSKIMISDFGLSKMED 170
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 78.2 bits (184), Expect = 3e-14
Identities = 54/164 (32%), Positives = 84/164 (51%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V+ + E + T KV + ++ + + + RE K
Sbjct: 16 YVLGDTLGVGTFGKVN----IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V F V+EY +G +L Y+ +H + E EAR + Q++SA+ Y
Sbjct: 72 RHPHIIKLYQVISTP-TDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 131 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 169
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 78.2 bits (184), Expect = 3e-14
Identities = 54/171 (31%), Positives = 97/171 (56%)
Frame = +3
Query: 201 RFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKH 380
R+ Q + + Y +LG G FSEV A D + Q+ A K + K+ E K+ + +++
Sbjct: 9 RWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAKEALEGKEGS-MEN 65
Query: 381 ALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSI 560
+ +HK + HP IV L D++E G+ + +++ +G +L + + ER+A +
Sbjct: 66 EIAV--LHK-IKHPNIVALDDIYESGGHLYL-IMQLVSGGELFDRIVEKGFYTERDASRL 121
Query: 561 VMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMD 713
+ QV+ A+KYL+++ ++H DLKP N+L + +I I+DFGLS++ D
Sbjct: 122 IFQVLDAVKYLHDLG--IVHRDLKPENLLYYSLDEDSKIMISDFGLSKMED 170
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 78.2 bits (184), Expect = 3e-14
Identities = 54/171 (31%), Positives = 97/171 (56%)
Frame = +3
Query: 201 RFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKH 380
R+ Q + + Y +LG G FSEV A D + Q+ A K + K+ E K+ + +++
Sbjct: 9 RWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAKEALEGKEGS-MEN 65
Query: 381 ALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSI 560
+ +HK + HP IV L D++E G+ + +++ +G +L + + ER+A +
Sbjct: 66 EIAV--LHK-IKHPNIVALDDIYESGGHLYL-IMQLVSGGELFDRIVEKGFYTERDASRL 121
Query: 561 VMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMD 713
+ QV+ A+KYL+++ ++H DLKP N+L + +I I+DFGLS++ D
Sbjct: 122 IFQVLDAVKYLHDLG--IVHRDLKPENLLYYSLDEDSKIMISDFGLSKMED 170
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 52 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 104
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 105 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 162
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 163 -IIHRDLKAGNILFT---LDGDIKLADFGVS 189
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 77.8 bits (183), Expect = 4e-14
Identities = 53/151 (35%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F +V+KA + + A KV D K +++ ++ + E +I + DHP IV
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVI----DTKSEEE---LEDYMVEIDILASCDHPNIV 92
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD-FYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
KL D F + N+ ++E+C G +D L+ + + E + + + Q + AL YL++ K
Sbjct: 93 KLLDAFYYE-NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNK- 150
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+IH DLK GNIL T + G+IK+ DFG+S
Sbjct: 151 -IIHRDLKAGNILFT---LDGDIKLADFGVS 177
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/164 (32%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V + E + T KV + ++ + + + RE K
Sbjct: 16 YVLGDTLGVGTFGKVK----IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V F V+EY +G +L Y+ +H + E EAR + Q++SA+ Y
Sbjct: 72 RHPHIIKLYQVISTP-TDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 131 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 169
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/164 (32%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V + E + T KV + ++ + + + RE K
Sbjct: 16 YVLGDTLGVGTFGKVK----IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V F V+EY +G +L Y+ +H + E EAR + Q++SA+ Y
Sbjct: 72 RHPHIIKLYQVISTP-TDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 131 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 169
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/164 (32%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V + E + T KV + ++ + + + RE K
Sbjct: 16 YVLGDTLGVGTFGKVK----IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V F V+EY +G +L Y+ +H + E EAR + Q++SA+ Y
Sbjct: 72 RHPHIIKLYQVISTP-TDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 131 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 169
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/164 (32%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V + E + T KV + ++ + + + RE K
Sbjct: 16 YVLGDTLGVGTFGKVK----IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V F V+EY +G +L Y+ +H + E EAR + Q++SA+ Y
Sbjct: 72 RHPHIIKLYQVISTP-TDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 131 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 169
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/164 (32%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V + E + T KV + ++ + + + RE K
Sbjct: 16 YVLGDTLGVGTFGKVK----IGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V F V+EY +G +L Y+ +H + E EAR + Q++SA+ Y
Sbjct: 72 RHPHIIKLYQVISTP-TDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 131 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 169
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/157 (34%), Positives = 84/157 (53%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG+G FS K K + A K+ + K+ +K L E HP IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALK--LCE-------GHPNIV 482
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KL++VF ++F V+E NG +L +K+ K E EA I+ ++VSA+ +++++
Sbjct: 483 KLHEVFHDQLHTFL-VMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVG-- 539
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
V+H DLKP N+L T+ N EIKI DFG +++ +N
Sbjct: 540 VVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDN 576
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 3/166 (1%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
E + LL +LG G + +V + ++ K +KA +H E + +
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 408 AL-DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSAL 584
+ P +V L+ F+ + +L+Y NG +L +L Q + E E + V ++V AL
Sbjct: 107 HIRQSPFLVTLHYAFQTE-TKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 585 KYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQ--VMDE 716
++L+++ +I+ D+K NILL G + +TDFGLS+ V DE
Sbjct: 166 EHLHKLG--IIYRDIKLENILLDSN---GHVVLTDFGLSKEFVADE 206
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 77.4 bits (182), Expect = 5e-14
Identities = 54/157 (34%), Positives = 84/157 (53%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG+G FS K K + A K+ + K+ +K L E HP IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALK--LCE-------GHPNIV 482
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KL++VF ++F V+E NG +L +K+ K E EA I+ ++VSA+ +++++
Sbjct: 483 KLHEVFHDQLHTFL-VMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVG-- 539
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
V+H DLKP N+L T+ N EIKI DFG +++ +N
Sbjct: 540 VVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDN 576
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 3/166 (1%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
E + LL +LG G + +V + ++ K +KA +H E + +
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 408 AL-DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSAL 584
+ P +V L+ F+ + +L+Y NG +L +L Q + E E + V ++V AL
Sbjct: 107 HIRQSPFLVTLHYAFQTE-TKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 585 KYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQ--VMDE 716
++L+++ +I+ D+K NILL G + +TDFGLS+ V DE
Sbjct: 166 EHLHKLG--IIYRDIKLENILLDSN---GHVVLTDFGLSKEFVADE 206
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 77.0 bits (181), Expect = 7e-14
Identities = 54/153 (35%), Positives = 86/153 (56%), Gaps = 1/153 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A + + A KV L K ++K KH + E N+ K + H
Sbjct: 165 LKVIGKGSFGKVLLAKRKLDGKVYAVKV--LQKKIVLNRKEQ--KHIMAERNVLLKNVKH 220
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL++ NG +L F+L++ ++ PE AR ++ SAL YL+
Sbjct: 221 PFLVGLHYSFQTTEKLYF-VLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHS 279
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
IK +++ DLKP NIL+ + G + +TDFGL
Sbjct: 280 IK--IVYRDLKPENILV---DSVGHVVLTDFGL 307
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 251
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 252 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 310
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 311 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 346
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 156
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 157 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 216 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 251
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 156
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 157 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 216 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 251
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 251
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 252 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 310
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 311 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 346
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 251
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 252 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 310
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 311 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 346
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 115 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 170
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 171 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 229
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 230 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 265
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 156
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 157 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 216 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 251
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 91 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 146
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 147 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 205
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 206 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 241
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 156
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 157 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 216 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 251
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 76.6 bits (180), Expect = 9e-14
Identities = 55/161 (34%), Positives = 86/161 (53%), Gaps = 1/161 (0%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH-KALDH 419
L ++GKG F +V A E+ + A KV Q K+ ++ KH + E N+ K + H
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEE----KHIMSERNVLLKNVKH 156
Query: 420 PRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
P +V L+ F+ + VL+Y NG +L ++L++ + E AR ++ SAL YL+
Sbjct: 157 PFLVGLHFSFQT-ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
+ +++ DLKP NILL G I +TDFGL + E N
Sbjct: 216 LN--IVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEHN 251
>AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens
cDNA FLJ14396 fis, clone HEMBA1003291, moderately
similar to SNF1-RELATED PROTEIN KINASE KIN10 (EC
2.7.1.-). ).
Length = 208
Score = 76.2 bits (179), Expect = 1e-13
Identities = 47/137 (34%), Positives = 75/137 (54%)
Frame = +3
Query: 222 LSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNI 401
L RY L LGKG + +V +A + R A K + KD +D++ + H RE I
Sbjct: 51 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIK--SVRKDKIKDEQD--MVHIRREIEI 106
Query: 402 HKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSA 581
+L+HP I+ +Y+VFE + + ++EY + +L Y+ + + + ERE R Q+VSA
Sbjct: 107 MSSLNHPHIISIYEVFE-NKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSA 165
Query: 582 LKYLNEIKPPVIHYDLK 632
+ Y + K V+H DLK
Sbjct: 166 VHYCH--KNGVVHRDLK 180
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 76.2 bits (179), Expect = 1e-13
Identities = 54/157 (34%), Positives = 83/157 (52%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG+G FS K K + K+ + K+ +K L E HP IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQALQVKIISKRMEANTQKEITALK--LCE-------GHPNIV 482
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KL++VF ++F V+E NG +L L++ K E EA I+ ++VSAL +++++
Sbjct: 483 KLHEVFHDQLHTFL-VMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLG-- 539
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
V+H DLKP N+L T+ N EIKI DFG +++ +N
Sbjct: 540 VVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDN 576
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 3/166 (1%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
E + LL +LG G + +V + ++ K +KA +H E + +
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 408 AL-DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSAL 584
+ P +V L+ F+ + +L+Y NG +L +L Q + E E + V ++V AL
Sbjct: 107 HIRQSPFLVTLHYAFQTE-TKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 585 KYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQ--VMDE 716
++L+++ +I+ D+K NILL G + +TDFGLS+ V DE
Sbjct: 166 EHLHKLG--IIYRDIKLENILLDSN---GHVVLTDFGLSKEFVADE 206
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 77
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 78 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 134
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 135 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/158 (30%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + K ++ + RE +I K + HP ++
Sbjct: 22 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-KSSRRGVSREDIEREVSILKEIQHPNVI 80
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L++V+E + +LE G +L +L + +++ E EA + Q+++ + YL+ ++
Sbjct: 81 TLHEVYE-NKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQ-- 137
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDEEN 722
+ H+DLKP NI+L + NV IKI DFGL+ +D N
Sbjct: 138 IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 175
>U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase
protein.
Length = 299
Score = 75.4 bits (177), Expect = 2e-13
Identities = 40/105 (38%), Positives = 59/105 (56%)
Frame = +3
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
+E +H+ L H +V+ Y FE D + +LEYC+ + LK K + E E R +
Sbjct: 20 KEIELHRILHHKHVVQFYHYFE-DKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLR 78
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
Q+VS LKYL+E ++H DLK GN + E E+K+ DFGL+
Sbjct: 79 QIVSGLKYLHE--QEILHRDLKLGNFFINEAM---ELKVGDFGLA 118
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/152 (34%), Positives = 79/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + RY A K+ + +D+ A H + E + + HP
Sbjct: 155 LKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVA----HTVTESRVLQNTRHP 210
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E AR ++VSAL+YL+
Sbjct: 211 FLTALKYAFQTH-DRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH-- 267
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
V++ D+K N++L + G IKITDFGL
Sbjct: 268 SRDVVYRDIKLENLMLDKD---GHIKITDFGL 296
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/152 (34%), Positives = 79/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + RY A K+ + +D+ A H + E + + HP
Sbjct: 155 LKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVA----HTVTESRVLQNTRHP 210
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E AR ++VSAL+YL+
Sbjct: 211 FLTALKYAFQTH-DRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH-- 267
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
V++ D+K N++L + G IKITDFGL
Sbjct: 268 SRDVVYRDIKLENLMLDKD---GHIKITDFGL 296
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/176 (28%), Positives = 89/176 (50%), Gaps = 1/176 (0%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
S F Q V + Y + LG G F+ V K + A K + + ++ +
Sbjct: 2 STFRQEDV-EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRR-LSSSRRGVSRE 59
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
RE NI + + HP I+ L+D+FE + +LE +G +L +L + +++ E EA
Sbjct: 60 EIEREVNILREIRHPNIITLHDIFE-NKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCG-EIKITDFGLSQVMDEEN 722
+ Q++ + YL+ + + H+DLKP NI+L + NV IK+ DFG++ ++ N
Sbjct: 119 FLKQILDGVHYLHSKR--IAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGN 172
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/176 (28%), Positives = 89/176 (50%), Gaps = 1/176 (0%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
S F Q V + Y + LG G F+ V K + A K + + ++ +
Sbjct: 2 STFRQEDV-EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRR-LSSSRRGVSRE 59
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
RE NI + + HP I+ L+D+FE + +LE +G +L +L + +++ E EA
Sbjct: 60 EIEREVNILREIRHPNIITLHDIFE-NKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCG-EIKITDFGLSQVMDEEN 722
+ Q++ + YL+ + + H+DLKP NI+L + NV IK+ DFG++ ++ N
Sbjct: 119 FLKQILDGVHYLHSKR--IAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGN 172
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/152 (34%), Positives = 79/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + RY A K+ + +D+ A H + E + + HP
Sbjct: 155 LKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVA----HTVTESRVLQNTRHP 210
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E AR ++VSAL+YL+
Sbjct: 211 FLTALKYAFQTH-DRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH-- 267
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
V++ D+K N++L + G IKITDFGL
Sbjct: 268 SRDVVYRDIKLENLMLDKD---GHIKITDFGL 296
>BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein.
Length = 344
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/152 (34%), Positives = 79/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + RY A K+ + +D+ A H + E + + HP
Sbjct: 155 LKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVA----HTVTESRVLQNTRHP 210
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E AR ++VSAL+YL+
Sbjct: 211 FLTALKYAFQTH-DRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH-- 267
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
V++ D+K N++L + G IKITDFGL
Sbjct: 268 SRDVVYRDIKLENLMLDKD---GHIKITDFGL 296
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/152 (34%), Positives = 78/152 (51%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++L + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMLDKD---GHIKITDFGL 292
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/176 (28%), Positives = 89/176 (50%), Gaps = 1/176 (0%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
S F Q V + Y + LG G F+ V K + A K + + ++ +
Sbjct: 2 STFRQEDV-EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRR-LSSSRRGVSRE 59
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
RE NI + + HP I+ L+D+FE + +LE +G +L +L + +++ E EA
Sbjct: 60 EIEREVNILREIRHPNIITLHDIFE-NKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCG-EIKITDFGLSQVMDEEN 722
+ Q++ + YL+ + + H+DLKP NI+L + NV IK+ DFG++ ++ N
Sbjct: 119 FLKQILDGVHYLHSKR--IAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGN 172
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/176 (28%), Positives = 89/176 (50%), Gaps = 1/176 (0%)
Frame = +3
Query: 198 SRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIK 377
S F Q V + Y + LG G F+ V K + A K + + ++ +
Sbjct: 2 STFRQEDV-EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRR-LSSSRRGVSRE 59
Query: 378 HALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARS 557
RE NI + + HP I+ L+D+FE + +LE +G +L +L + +++ E EA
Sbjct: 60 EIEREVNILREIRHPNIITLHDIFE-NKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 558 IVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCG-EIKITDFGLSQVMDEEN 722
+ Q++ + YL+ + + H+DLKP NI+L + NV IK+ DFG++ ++ N
Sbjct: 119 FLKQILDGVHYLHSKR--IAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGN 172
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 74.1 bits (174), Expect = 5e-13
Identities = 54/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A LKE + L +K + ++H LR E I L HP I
Sbjct: 15 LGKGKFGNVYLA-RLKESHFIVA----LKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 69
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ + + E+ +I+ +V AL Y ++ K
Sbjct: 70 LRLYNYFH-DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDKK- 127
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL GE+KI DFG S
Sbjct: 128 -VIHRDIKPENLLL---GFRGEVKIADFGWS 154
>L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 73.3 bits (172), Expect = 9e-13
Identities = 55/162 (33%), Positives = 83/162 (51%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D+ + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDVDTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 73.3 bits (172), Expect = 9e-13
Identities = 51/152 (33%), Positives = 82/152 (53%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+GKG F+ V +A L + A K+ ++K +++ +K RE I K L HP I+
Sbjct: 14 IGKGNFAVVKRATHLVTKAKVAIKI--IDKTQLDEEN---LKKIFREVQIMKMLCHPHII 68
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
+LY V E + V EY +G ++ +L H + E+EAR Q+V+A+ + +
Sbjct: 69 RLYQVMETE-RMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH--CRN 125
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
++H DLK N+LL + N+ IKI DFG S +
Sbjct: 126 IVHRDLKAENLLL-DANL--NIKIADFGFSNL 154
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 73.3 bits (172), Expect = 9e-13
Identities = 51/152 (33%), Positives = 82/152 (53%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+GKG F+ V +A L + A K+ ++K +++ +K RE I K L HP I+
Sbjct: 122 IGKGNFAVVKRATHLVTKAKVAIKI--IDKTQLDEEN---LKKIFREVQIMKMLCHPHII 176
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
+LY V E + V EY +G ++ +L H + E+EAR Q+V+A+ + +
Sbjct: 177 RLYQVMETE-RMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH--CRN 233
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
++H DLK N+LL + N+ IKI DFG S +
Sbjct: 234 IVHRDLKAENLLL-DANL--NIKIADFGFSNL 262
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/148 (37%), Positives = 74/148 (50%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LGKG F+ V L R T +V D K A ++ RE I K LDHP I+
Sbjct: 26 LGKGNFAVVK----LGRHRITKTEVAIKIID-KSQLDAVNLEKIYREVQIMKMLDHPHII 80
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KLY V E + V EY ++ YL H + E EAR Q++SA+ Y + K
Sbjct: 81 KLYQVMETKSMLY-LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK-- 137
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFG 695
++H DLK N+LL + N+ IKI DFG
Sbjct: 138 IVHRDLKAENLLL-DNNM--NIKIADFG 162
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/148 (37%), Positives = 74/148 (50%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LGKG F+ V L R T +V D K A ++ RE I K LDHP I+
Sbjct: 26 LGKGNFAVVK----LGRHRITKTEVAIKIID-KSQLDAVNLEKIYREVQIMKMLDHPHII 80
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KLY V E + V EY ++ YL H + E EAR Q++SA+ Y + K
Sbjct: 81 KLYQVMETKSMLY-LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK-- 137
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFG 695
++H DLK N+LL + N+ IKI DFG
Sbjct: 138 IVHRDLKAENLLL-DNNM--NIKIADFG 162
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A LKE + L +K + ++H LR E I L HP I
Sbjct: 15 LGKGKFGNVYLA-RLKESHFIVA----LKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 69
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ + + E+ +I+ ++ AL Y ++ K
Sbjct: 70 LRLYNYFH-DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK- 127
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL GE+KI DFG S
Sbjct: 128 -VIHRDIKPENLLL---GFRGEVKIADFGWS 154
>BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase
32B protein.
Length = 414
Score = 72.9 bits (171), Expect = 1e-12
Identities = 51/179 (28%), Positives = 88/179 (49%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
+ + +L +GKG F +V ++ A K K + D+ +++ RE I +
Sbjct: 21 DHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDE----VRNVFRELQIMQ 76
Query: 408 ALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALK 587
L+HP +V L+ F+ + + F V++ G DL ++L+Q+ E + + ++ AL+
Sbjct: 77 GLEHPFLVNLWYSFQDEEDMFM-VVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALE 135
Query: 588 YLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT*PAREP 764
YL +IH D+KP NILL E G + ITDF ++ V+ +A T P P
Sbjct: 136 YLQRYH--IIHRDIKPDNILLDEH---GHVHITDFNIATVVKGAERASSMAGTKPYMAP 189
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A LKE + L +K + ++H LR E I L HP I
Sbjct: 46 LGKGKFGNVYLA-RLKESHFIVA----LKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 100
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ + + E+ +I+ ++ AL Y ++ K
Sbjct: 101 LRLYNYFH-DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK- 158
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL GE+KI DFG S
Sbjct: 159 -VIHRDIKPENLLL---GFRGEVKIADFGWS 185
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A LKE + L +K + ++H LR E I L HP I
Sbjct: 30 LGKGKFGNVYLA-RLKESHFIVA----LKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 84
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ + + E+ +I+ ++ AL Y ++ K
Sbjct: 85 LRLYNYFH-DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK- 142
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL GE+KI DFG S
Sbjct: 143 -VIHRDIKPENLLL---GFRGEVKIADFGWS 169
>AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protein
kinase protein.
Length = 414
Score = 72.9 bits (171), Expect = 1e-12
Identities = 51/179 (28%), Positives = 88/179 (49%)
Frame = +3
Query: 228 ERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHK 407
+ + +L +GKG F +V ++ A K K + D+ +++ RE I +
Sbjct: 21 DHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDE----VRNVFRELQIMQ 76
Query: 408 ALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALK 587
L+HP +V L+ F+ + + F V++ G DL ++L+Q+ E + + ++ AL+
Sbjct: 77 GLEHPFLVNLWYSFQDEEDMFM-VVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALE 135
Query: 588 YLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT*PAREP 764
YL +IH D+KP NILL E G + ITDF ++ V+ +A T P P
Sbjct: 136 YLQRYH--IIHRDIKPDNILLDEH---GHVHITDFNIATVVKGAERASSMAGTKPYMAP 189
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 72.9 bits (171), Expect = 1e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 1/166 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNK-DWKEDKKANYIKHALREYNIHKALDHPRI 428
LG G EV AF+ K + A K+ K ++A+ + E I K L+HP I
Sbjct: 5 LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCI 64
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
+K+ + F D + VLE G +L + +K + E + Q++ A++YL+E
Sbjct: 65 IKIKNFF--DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHE--N 120
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT 746
+IH DLKP N+LL+ IKITDFG S+++ E + L T
Sbjct: 121 GIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 166
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 72.9 bits (171), Expect = 1e-12
Identities = 57/160 (35%), Positives = 80/160 (50%), Gaps = 6/160 (3%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
L+G G F+ V K +E+ V +NK K K+ + +E I K L H I
Sbjct: 21 LIGHGAFAVVFKGRH-REKHDLEVAVKCINK--KNLAKSQTLLG--KEIKILKELKHENI 75
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
V LYD E+ NS V+EYCNG DL YL +T+ E R + Q+ A++ L+
Sbjct: 76 VALYDFQEM-ANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLH--SK 132
Query: 609 PVIHYDLKPGNILLTE--GNVCG----EIKITDFGLSQVM 710
+IH DLKP NILL+ G +KI DFG ++ +
Sbjct: 133 GIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYL 172
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/148 (37%), Positives = 74/148 (50%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LGKG F+ V L R T +V D K A ++ RE I K LDHP I+
Sbjct: 24 LGKGNFAVVK----LGRHRITKTEVAIKIID-KSQLDAVNLEKIYREVQIMKMLDHPHII 78
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KLY V E + V EY ++ YL H + E EAR Q++SA+ Y + K
Sbjct: 79 KLYQVMETKSMLY-LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK-- 135
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFG 695
++H DLK N+LL + N+ IKI DFG
Sbjct: 136 IVHRDLKAENLLL-DNNM--NIKIADFG 160
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/148 (37%), Positives = 74/148 (50%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LGKG F+ V L R T +V D K A ++ RE I K LDHP I+
Sbjct: 50 LGKGNFAVVK----LGRHRITKTEVAIKIID-KSQLDAVNLEKIYREVQIMKMLDHPHII 104
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
KLY V E + V EY ++ YL H + E EAR Q++SA+ Y + K
Sbjct: 105 KLYQVMETKSMLY-LVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK-- 161
Query: 612 VIHYDLKPGNILLTEGNVCGEIKITDFG 695
++H DLK N+LL + N+ IKI DFG
Sbjct: 162 IVHRDLKAENLLL-DNNM--NIKIADFG 186
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 72.9 bits (171), Expect = 1e-12
Identities = 57/160 (35%), Positives = 80/160 (50%), Gaps = 6/160 (3%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
L+G G F+ V K +E+ V +NK K K+ + +E I K L H I
Sbjct: 37 LIGHGAFAVVFKGRH-REKHDLEVAVKCINK--KNLAKSQTLLG--KEIKILKELKHENI 91
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
V LYD E+ NS V+EYCNG DL YL +T+ E R + Q+ A++ L+
Sbjct: 92 VALYDFQEM-ANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLH--SK 148
Query: 609 PVIHYDLKPGNILLTE--GNVCG----EIKITDFGLSQVM 710
+IH DLKP NILL+ G +KI DFG ++ +
Sbjct: 149 GIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYL 188
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A LKE + L +K + ++H LR E I L HP I
Sbjct: 49 LGKGKFGNVYLA-RLKESHFIVA----LKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 103
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ + + E+ +I+ ++ AL Y ++ K
Sbjct: 104 LRLYNYFH-DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK- 161
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL GE+KI DFG S
Sbjct: 162 -VIHRDIKPENLLL---GFRGEVKIADFGWS 188
>X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 72.5 bits (170), Expect = 2e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 72.5 bits (170), Expect = 2e-12
Identities = 52/152 (34%), Positives = 77/152 (50%)
Frame = +3
Query: 243 LMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 422
L LLGKG F +V + +Y A K+ + +D+ A H L E + K HP
Sbjct: 151 LKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVA----HTLTESRVLKNTRHP 206
Query: 423 RIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEI 602
+ L F+ + C V+EY NG +L F+L + + E R ++VSAL YL+
Sbjct: 207 FLTSLKYSFQTK-DRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 603 KPPVIHYDLKPGNILLTEGNVCGEIKITDFGL 698
K +++ DLK N++ + G IKITDFGL
Sbjct: 266 K--IVYRDLKLENLMRDKD---GHIKITDFGL 292
>BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 72.5 bits (170), Expect = 2e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 72.5 bits (170), Expect = 2e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 72.5 bits (170), Expect = 2e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delta
protein.
Length = 247
Score = 72.5 bits (170), Expect = 2e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>Z84469-2|CAI42732.1| 1790|Homo sapiens WNK lysine deficient protein
kinase 3 protein.
Length = 1790
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>Z84469-1|CAI42733.1| 1743|Homo sapiens WNK lysine deficient protein
kinase 3 protein.
Length = 1743
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/166 (32%), Positives = 82/166 (49%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
QH Y L LGKG V + A K+ +N+ E + + R
Sbjct: 26 QHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKI--VNR---EKLSESVLMKVER 80
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR Q
Sbjct: 81 EIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
+VSAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 140 IVSALDFCHSYS--ICHRDLKPENLLLDEKN---NIRIADFGMASL 180
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/166 (32%), Positives = 82/166 (49%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
QH Y L LGKG V + A K+ +N+ E + + R
Sbjct: 26 QHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKI--VNR---EKLSESVLMKVER 80
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR Q
Sbjct: 81 EIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
+VSAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 140 IVSALDFCHSYS--ICHRDLKPENLLLDEKN---NIRIADFGMASL 180
>AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase
WNK3 protein.
Length = 1800
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase
WNK3 protein.
Length = 1800
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AL591766-2|CAI40707.1| 1790|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1790
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AL591766-1|CAI40708.1| 1743|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1743
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AL049793-2|CAI43128.1| 1790|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1790
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AL049793-1|CAI43129.1| 1743|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1743
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AJ409088-1|CAC32455.2| 1743|Homo sapiens protein kinase WNK3
protein.
Length = 1743
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/157 (33%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTA-CKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
LG+G F V+K D + A C++ E ++ E + K L HP I
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFK------EEAEMLKGLQHPNI 206
Query: 429 VKLYDVFE-IDGNSFCTVL--EYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNE 599
V+ YD +E I C VL E L YLK+ K + + RS Q++ L++L+
Sbjct: 207 VRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHT 266
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVM 710
PP+IH DLK NI +T G +KI D GL+ +M
Sbjct: 267 RTPPIIHRDLKCDNIFIT--GPTGSVKIGDLGLATLM 301
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/166 (32%), Positives = 82/166 (49%)
Frame = +3
Query: 210 QHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR 389
QH Y L LGKG V + A K+ +N+ E + + R
Sbjct: 26 QHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKI--VNR---EKLSESVLMKVER 80
Query: 390 EYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQ 569
E I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR Q
Sbjct: 81 EIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 570 VVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
+VSAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 140 IVSALDFCHSYS--ICHRDLKPENLLLDEKN---NIRIADFGMASL 180
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 72.1 bits (169), Expect = 2e-12
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A LKE + L +K + ++H LR E I L HP I
Sbjct: 49 LGKGKFGNVYLA-RLKESHFIVA----LKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 103
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ + + E+ +I+ ++ AL Y ++ K
Sbjct: 104 LRLYNHFH-DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK- 161
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL GE+KI DFG S
Sbjct: 162 -VIHRDIKPENLLL---GFRGEVKIADFGWS 188
>X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein
kinase protein.
Length = 603
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LGKGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLEPHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>U01038-1|AAA56634.1| 603|Homo sapiens pLK protein.
Length = 603
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/162 (33%), Positives = 82/162 (50%)
Frame = +3
Query: 216 PVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREY 395
P RY+ LL KGGF++ + D + A K+ + K ++ K ++ E
Sbjct: 47 PRSRRRYVRGRLLSKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQRE---KMSM-EI 102
Query: 396 NIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVV 575
+IH++L H +V + FE D + VLE C L K+ K + E EAR + Q+V
Sbjct: 103 SIHRSLAHQHVVGFHGFFE-DNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIV 161
Query: 576 SALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
+YL+ + VIH DLK GN+ L E E+KI DFGL+
Sbjct: 162 LGCQYLHRNR--VIHRDLKLGNLFLNEDL---EVKIGDFGLA 198
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 110 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 164
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 165 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 222
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 223 -VIHRDIKPENLLL---GLKGELKIADFGWS 249
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 71.7 bits (168), Expect = 3e-12
Identities = 54/173 (31%), Positives = 84/173 (48%)
Frame = +3
Query: 189 EDQSRFSQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKAN 368
E+ +H Y L LGKG V + A K+ +N+ E +
Sbjct: 35 EEAEERGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKI--VNR---EKLSES 89
Query: 369 YIKHALREYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPERE 548
+ RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +E
Sbjct: 90 VLMKVEREIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKE 148
Query: 549 ARSIVMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
AR Q+VSAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 149 ARKFFRQIVSALDFCHSYS--ICHRDLKPENLLLDEKN---NIRIADFGMASL 196
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein.
Length = 302
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/155 (32%), Positives = 82/155 (52%), Gaps = 4/155 (2%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
+G+G FSEV++A L + A K Q+ +A+ IK E ++ K L+HP ++
Sbjct: 40 IGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIK----EIDLLKQLNHPNVI 95
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLD----FYLKQHKTIPEREARSIVMQVVSALKYLNE 599
K Y F I+ N VLE + DL + KQ + IPER +Q+ SAL++++
Sbjct: 96 KYYASF-IEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHS 154
Query: 600 IKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQ 704
+ V+H D+KP N+ +T G +K+ D GL +
Sbjct: 155 RR--VMHRDIKPANVFIT---ATGVVKLGDLGLGR 184
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 71.7 bits (168), Expect = 3e-12
Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 1/151 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALR-EYNIHKALDHPRI 428
LGKG F V+ A + K A KV ++ KE ++H LR E I L HP I
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-----VEHQLRREIEIQAHLHHPNI 137
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKP 608
++LY+ F D +LEY +L L++ T E+ +I+ ++ AL Y + K
Sbjct: 138 LRLYNYF-YDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK- 195
Query: 609 PVIHYDLKPGNILLTEGNVCGEIKITDFGLS 701
VIH D+KP N+LL + GE+KI DFG S
Sbjct: 196 -VIHRDIKPENLLL---GLKGELKIADFGWS 222
>Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein
kinase protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinase
(CAK) protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase
protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase
protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine
kinase protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 71.3 bits (167), Expect = 4e-12
Identities = 45/156 (28%), Positives = 83/156 (53%), Gaps = 1/156 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + + ++ + RE +I + + H ++
Sbjct: 29 LGSGQFAIVKKCREKSTGLEYAAKFIKKRQS-RASRRGVSREEIEREVSILRQVLHHNVI 87
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L+DV+E + +LE +G +L +L Q +++ E EA S + Q++ + YL+ K
Sbjct: 88 TLHDVYE-NRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKK-- 144
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDE 716
+ H+DLKP NI+L + N+ IK+ DFGL+ +++
Sbjct: 145 IAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED 180
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/164 (31%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V A K+ LN+ ++ + + + RE K
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKI--LNR--QKIRSLDVVGKIRREIQNLKLF 73
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V + F V+EY +G +L Y+ ++ + E+E+R + Q++S + Y
Sbjct: 74 RHPHIIKLYQVISTPSDIFM-VMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 132
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 133 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 171
>BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein.
Length = 363
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG G F V+ K R A KV ++K K+ + +++ E I ++L HP I
Sbjct: 41 VLGSGQFGVVYGGKHRKTGRDVAVKV--IDKLRFPTKQESQLRN---EVAILQSLRHPGI 95
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSALKYLNEIK 605
V L +FE F V+E +G L+ L K +PER + ++ Q++ AL++L+
Sbjct: 96 VNLECMFETPEKVF-VVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKN 154
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT 746
++H DLKP N+LL + ++K+ DFG ++++ E+++ + T
Sbjct: 155 --IVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGT 199
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/164 (31%), Positives = 83/164 (50%)
Frame = +3
Query: 234 YLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKAL 413
Y+L LG G F +V A K+ LN+ ++ + + + RE K
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKI--LNR--QKIRSLDVVGKIRREIQNLKLF 73
Query: 414 DHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYL 593
HP I+KLY V + F V+EY +G +L Y+ ++ + E+E+R + Q++S + Y
Sbjct: 74 RHPHIIKLYQVISTPSDIFM-VMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 132
Query: 594 NEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENY 725
+ + V+H DLKP N+LL + KI DFGLS +M + +
Sbjct: 133 H--RHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDGEF 171
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL+ + ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLH--RHWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase 7
protein.
Length = 346
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 225 SERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIH 404
++RY L LG+G F+ V+KA D + A K +L + + K + ALRE +
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGH--RSEAKDGINRTALREIKLL 66
Query: 405 KALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSA 581
+ L HP I+ L D F N V ++ DL+ +K + + ++ ++ +
Sbjct: 67 QELSHPNIIGLLDAFGHKSN-ISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
Query: 582 LKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEEN 722
L+YL++ ++H DLKP N+LL E G +K+ DFGL++ N
Sbjct: 125 LEYLHQ--HWILHRDLKPNNLLLDEN---GVLKLADFGLAKSFGSPN 166
>AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90785 fis, clone THYRO1001457, moderately
similar to H.sapiens mRNA for protein kinase C mu. ).
Length = 721
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG G F V+ K R A KV ++K K+ + +++ E I ++L HP I
Sbjct: 399 VLGSGQFGVVYGGKHRKTGRDVAVKV--IDKLRFPTKQESQLRN---EVAILQSLRHPGI 453
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSALKYLNEIK 605
V L +FE F V+E +G L+ L K +PER + ++ Q++ AL++L+
Sbjct: 454 VNLECMFETPEKVF-VVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKN 512
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT 746
++H DLKP N+LL + ++K+ DFG ++++ E+++ + T
Sbjct: 513 --IVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGT 557
>AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90192 fis, clone MAMMA1001150, moderately
similar to PROTEIN KINASE C, MU TYPE (EC 2.7.1.-). ).
Length = 721
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG G F V+ K R A KV ++K K+ + +++ E I ++L HP I
Sbjct: 399 VLGSGQFGVVYGGKHRKTGRDVAVKV--IDKLRFPTKQESQLRN---EVAILQSLRHPGI 453
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSALKYLNEIK 605
V L +FE F V+E +G L+ L K +PER + ++ Q++ AL++L+
Sbjct: 454 VNLECMFETPEKVF-VVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKN 512
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT 746
++H DLKP N+LL + ++K+ DFG ++++ E+++ + T
Sbjct: 513 --IVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGT 557
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 71.3 bits (167), Expect = 4e-12
Identities = 53/167 (31%), Positives = 83/167 (49%)
Frame = +3
Query: 207 SQHPVLSERYLLLMLLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHAL 386
+QH Y L LGKG V + A K+ +N+ E + +
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKI--VNR---EKLSESVLMKVE 64
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 65 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 123
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q++SAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 124 QIISALDFCH--SHSICHRDLKPENLLLDEKN---NIRIADFGMASL 165
>AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein.
Length = 878
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/167 (29%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 249 LLGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRI 428
+LG G F V+ K R A KV ++K K+ + +++ E I ++L HP I
Sbjct: 556 VLGSGQFGVVYGGKHRKTGRDVAVKV--IDKLRFPTKQESQLRN---EVAILQSLRHPGI 610
Query: 429 VKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHK-TIPEREARSIVMQVVSALKYLNEIK 605
V L +FE F V+E +G L+ L K +PER + ++ Q++ AL++L+
Sbjct: 611 VNLECMFETPEKVF-VVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKN 669
Query: 606 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQVMDEENYNPDLAWT 746
++H DLKP N+LL + ++K+ DFG ++++ E+++ + T
Sbjct: 670 --IVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGT 714
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 71.3 bits (167), Expect = 4e-12
Identities = 45/156 (28%), Positives = 83/156 (53%), Gaps = 1/156 (0%)
Frame = +3
Query: 252 LGKGGFSEVHKAFDLKEQRYTACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRIV 431
LG G F+ V K + A K + + + ++ + RE +I + + H ++
Sbjct: 29 LGSGQFAIVKKCREKSTGLEYAAKFIKKRQS-RASRRGVSREEIEREVSILRQVLHHNVI 87
Query: 432 KLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVMQVVSALKYLNEIKPP 611
L+DV+E + +LE +G +L +L Q +++ E EA S + Q++ + YL+ K
Sbjct: 88 TLHDVYE-NRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKK-- 144
Query: 612 VIHYDLKPGNILLTEGNV-CGEIKITDFGLSQVMDE 716
+ H+DLKP NI+L + N+ IK+ DFGL+ +++
Sbjct: 145 IAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED 180
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 71.3 bits (167), Expect = 4e-12
Identities = 41/107 (38%), Positives = 63/107 (58%)
Frame = +3
Query: 387 REYNIHKALDHPRIVKLYDVFEIDGNSFCTVLEYCNGHDLDFYLKQHKTIPEREARSIVM 566
RE I K ++HP ++KL+DV+E + VLE+ +G +L YL + + +EAR
Sbjct: 17 REIAILKLIEHPHVLKLHDVYE-NKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFR 75
Query: 567 QVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSQV 707
Q+VSAL + + + H DLKP N+LL E N I+I DFG++ +
Sbjct: 76 QIVSALDFCHSYS--ICHRDLKPENLLLDEKN---NIRIADFGMASL 117
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,983,114
Number of Sequences: 237096
Number of extensions: 2391585
Number of successful extensions: 11133
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8647
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9331
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9367263024
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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