Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-0539
(669 letters)
Database: mosquito
2352 sequences; 563,979 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M93689-2|AAA29367.1| 975|Anopheles gambiae protein ( Anopheles ... 73 1e-14
AB090818-2|BAC57912.1| 988|Anopheles gambiae reverse transcript... 67 5e-13
AB090815-2|BAC57906.1| 973|Anopheles gambiae reverse transcript... 65 2e-12
AB090822-2|BAC57920.1| 1173|Anopheles gambiae reverse transcript... 65 2e-12
AB090816-2|BAC57908.1| 1201|Anopheles gambiae reverse transcript... 61 3e-11
AJ970245-1|CAI96717.1| 134|Anopheles gambiae putative reverse t... 61 4e-11
AB090814-2|BAC57904.1| 1049|Anopheles gambiae reverse transcript... 60 8e-11
M93691-2|AAA29365.1| 1222|Anopheles gambiae protein ( Anopheles ... 58 3e-10
AB090823-2|BAC57922.1| 1154|Anopheles gambiae reverse transcript... 55 2e-09
M93690-2|AAA29363.1| 1212|Anopheles gambiae unknown protein. 53 9e-09
AB090812-2|BAC57900.1| 1173|Anopheles gambiae reverse transcript... 52 1e-08
AB090813-2|BAC57902.1| 1099|Anopheles gambiae reverse transcript... 52 2e-08
AB090817-2|BAC57910.1| 1009|Anopheles gambiae reverse transcript... 52 2e-08
AB090819-2|BAC57914.1| 1022|Anopheles gambiae reverse transcript... 51 3e-08
AB090820-2|BAC57916.1| 1222|Anopheles gambiae reverse transcript... 44 4e-06
AB097127-1|BAC82595.1| 1209|Anopheles gambiae reverse transcript... 36 0.002
AY578811-1|AAT07316.1| 565|Anopheles gambiae thickveins protein. 24 3.8
AY324311-1|AAQ89696.1| 158|Anopheles gambiae insulin-like pepti... 23 6.6
>M93689-2|AAA29367.1| 975|Anopheles gambiae protein ( Anopheles
gambiae T1 retroposon. ).
Length = 975
Score = 72.5 bits (170), Expect = 1e-14
Identities = 48/163 (29%), Positives = 79/163 (48%), Gaps = 1/163 (0%)
Frame = -2
Query: 491 VAPSEIRKVILSIK-SNAVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRRA 315
V+ + +V+ +K S G D I ++I D L P + I N SL G FP LW+
Sbjct: 470 VSSETVVQVLFGLKRSFTPGPDGIPASVLINCKDVLAPHLAKIFNLSLSLGVFPALWKSC 529
Query: 314 YVRALPKIPDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSLISPFQSGFRPGHS 135
++ + K S+ +++R I+ +K E+C+ + +S ISP Q GF PG S
Sbjct: 530 WLFPVHKKGCRSIVSNYRGITQTCATAKTFELCIFPTILHSC--SSAISPKQHGFMPGRS 587
Query: 134 TISALLKVTGDIRVGLEESKITILVLVDFSNAFNTVCHDILLS 6
T + L+ +I E + DF AF+++ H +LL+
Sbjct: 588 TSTNLMSFVTNIFRSFEAGTQLDAIYTDFHAAFDSLPHSLLLA 630
>AB090818-2|BAC57912.1| 988|Anopheles gambiae reverse transcriptase
protein.
Length = 988
Score = 66.9 bits (156), Expect = 5e-13
Identities = 44/156 (28%), Positives = 76/156 (48%), Gaps = 6/156 (3%)
Frame = -2
Query: 479 EIRKVILSIK-SNAVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRRAYVRA 303
E++++ S+ A G DNI + L++G FP W+R +
Sbjct: 417 ELKEIARSLNPKKAPGDDNIPNMAAAAAILAFPEVFAKSYKQLLEAGTFPDAWKRQQLVL 476
Query: 302 LPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSLISPFQSGFRPGHSTIS 126
L K P P+ +RPI +L L K+LE + ++L+ + + +S Q GFR G ST+
Sbjct: 477 LTKSGKPPGEPSSYRPICLLSVLGKILERLIQRRLTTHLESTGGLSDPQYGFRKGRSTVD 536
Query: 125 ALLKVTGDIRVGLEE----SKITILVLVDFSNAFNT 30
A+ +V + +V L++ ++ +V VD NA N+
Sbjct: 537 AITRVMNNGKVALDKKRKGDRLCAVVTVDVRNALNS 572
>AB090815-2|BAC57906.1| 973|Anopheles gambiae reverse transcriptase
protein.
Length = 973
Score = 65.3 bits (152), Expect = 2e-12
Identities = 51/172 (29%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Frame = -2
Query: 527 RRPDVVPFQLFPVAPSEIRKVILSIK-SNAVGYDNICRRMIITILDCLLPAIYHIINFSL 351
R PDV P ++ EI+K +K A G D I I + L A +
Sbjct: 384 RNPDVEPVS---ISADEIQKAADHLKLGKAPGPDGIPIEAIKAAIKAYLEAFLSVFQNCF 440
Query: 350 DSGEFPFLWRRAYVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSL 174
D+G FP W+R + LPK P + RP++++ +K+LEI + +L +
Sbjct: 441 DTGFFPIPWKRQKLVLLPKPGKPPDDASALRPLALIDNFAKILEILILNRLVVYTEGEHG 500
Query: 173 ISPFQSGFRPGHSTISALLKVTGDIRVGLEE----SKITILVLVDFSNAFNT 30
+S Q GFR G ST A+ V R L + ++ +V +D NAFN+
Sbjct: 501 LSDRQFGFRKGRSTGEAIAAVLKKRRSALLKKRTGNRYCAIVTIDVKNAFNS 552
>AB090822-2|BAC57920.1| 1173|Anopheles gambiae reverse transcriptase
protein.
Length = 1173
Score = 64.9 bits (151), Expect = 2e-12
Identities = 53/172 (30%), Positives = 79/172 (45%), Gaps = 12/172 (6%)
Frame = -2
Query: 509 PFQLFPVAPSEIRKVILSIKSN-AVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFP 333
P+ + PV E+ ++ + S A G D I + T + I D GEFP
Sbjct: 427 PYHIRPVTDLELERIADDMCSRKAPGLDGIPNIALKTAIKKHTAVFRSIYQGCFDRGEFP 486
Query: 332 FLWR--RAYVRALPKIPDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFN--NSLISP 165
W+ R + P P P + FRP+ +L L KVLE + +L+ F+ N S +SP
Sbjct: 487 AHWKIQRLVLLQKPGKP-PGESSSFRPLGMLNGLGKVLERLILNRLNEFLENGETSHLSP 545
Query: 164 FQSGFRPGHSTISALLKVT-------GDIRVGLEESKITILVLVDFSNAFNT 30
Q GFR G ST+ +L+V R + + ++V +D NAFNT
Sbjct: 546 NQYGFRRGKSTVQGILRVVQAGRTAKSFNRTNGRDMRCLMVVSLDVRNAFNT 597
>AB090816-2|BAC57908.1| 1201|Anopheles gambiae reverse transcriptase
protein.
Length = 1201
Score = 61.3 bits (142), Expect = 3e-11
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Frame = -2
Query: 491 VAPSEIRKVILS-IKSNAVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRRA 315
V P E+ + + A G D I + ++ + L G FP W+R
Sbjct: 488 VEPQELLSIAAGMVTRKAPGLDGIPNAAVKVAIEEYTEEFCRLYQDCLSRGTFPPQWKRQ 547
Query: 314 YVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFI--FNNSLISPFQSGFRP 144
+ LPK P + +RP+ +L L KVLE + +L+R I ++ +S Q GFR
Sbjct: 548 RLVLLPKPGKPPGESSSYRPLCMLDALGKVLERLILNRLNRHIEQQDSPQLSDAQYGFRR 607
Query: 143 GHSTISALLKV--TGDI-----RVGLEESKITILVLVDFSNAFNT 30
G STISA+ +V G R + + ++V +D NAFNT
Sbjct: 608 GRSTISAIQRVVDAGTAAKLFRRTNTRDKRCLMVVALDIRNAFNT 652
>AJ970245-1|CAI96717.1| 134|Anopheles gambiae putative reverse
transcriptase protein.
Length = 134
Score = 60.9 bits (141), Expect = 4e-11
Identities = 34/87 (39%), Positives = 49/87 (56%)
Frame = -2
Query: 266 FRPISILPFLSKVLEICVHKQLSRFIFNNSLISPFQSGFRPGHSTISALLKVTGDIRVGL 87
+RPIS+L L K+ E + +++ FNN++I Q GFRP ST L +VT +I
Sbjct: 2 YRPISLLSCLGKIFEKLLESRMALHTFNNNIIPKSQFGFRPSLSTTHQLHRVTNNIVHNR 61
Query: 86 EESKITILVLVDFSNAFNTVCHDILLS 6
K T L L+D AF+++ H LLS
Sbjct: 62 CNRKSTGLALLDTEKAFDSIWHQGLLS 88
>AB090814-2|BAC57904.1| 1049|Anopheles gambiae reverse transcriptase
protein.
Length = 1049
Score = 59.7 bits (138), Expect = 8e-11
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 6/161 (3%)
Frame = -2
Query: 494 PVAPSEIRKVILSIK-SNAVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRR 318
P+ EI + +K A G D I I + +++ +L +G+FP +W+
Sbjct: 453 PITRQEIINLANRLKCGKAPGIDGIPNMAIKAAMLAYPDVFKNVLMNTLTTGQFPSMWKI 512
Query: 317 AYVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSLISPFQSGFRPG 141
+ +PK P P+ FRP+ ++ L+KV E+ + +L+++ +S Q GFR
Sbjct: 513 QKLVLIPKPGKPPGHPSAFRPLGLVDNLAKVQEMVILDRLTKYTEGPHGLSDRQFGFRKK 572
Query: 140 HSTISALLKVTGDIRVGLEE----SKITILVLVDFSNAFNT 30
ST+ A+L V + ++ L+ +D NAFN+
Sbjct: 573 RSTVDAILAVLEKGIAAFQRKRCGARYCALITIDVKNAFNS 613
>M93691-2|AAA29365.1| 1222|Anopheles gambiae protein ( Anopheles
gambiae RT2 retroposon. ).
Length = 1222
Score = 57.6 bits (133), Expect = 3e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Frame = -2
Query: 494 PVAPSEIRKVILSIKSN-AVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRR 318
PV E+ + + ++ A G D I + T + + + L+ FP W+R
Sbjct: 472 PVTDDELLLIASQMANHKAPGLDGIPNAAVKTAIMLFPESSGFLYQDCLNRASFPAQWKR 531
Query: 317 AYVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSL--ISPFQSGFR 147
+ LPK P + +RP+ +L L KVLE + +L+ + S +S Q GFR
Sbjct: 532 QRLVLLPKQGKPPGESSSYRPLCMLDALGKVLERLILNRLNEHLEEPSSPRLSDRQFGFR 591
Query: 146 PGHSTISALLKVTGDIRVGL-------EESKITILVLVDFSNAFNT 30
G ST+SA+ +V R + +++ ++V +D NAFNT
Sbjct: 592 RGRSTVSAIQRVVEAGRTAMSFRRTNGRDNRFLLVVALDVKNAFNT 637
>AB090823-2|BAC57922.1| 1154|Anopheles gambiae reverse transcriptase
protein.
Length = 1154
Score = 55.2 bits (127), Expect = 2e-09
Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 11/165 (6%)
Frame = -2
Query: 491 VAPSEIRKVILSIKSN-AVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRRA 315
V P E++ + + + A G D I + + + L G FP W+R
Sbjct: 427 VTPRELQDIAHQMATRKAPGLDGIPNAAVKAAIGMYPDVFCRMYQDCLTRGTFPSEWKRQ 486
Query: 314 YVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIF--NNSLISPFQSGFRP 144
+ L K P + +RP+S+L L KVLE + +L++ + ++ +S Q GFR
Sbjct: 487 RLVLLSKTGKPPGESSSYRPLSMLDALGKVLEQLILNRLNKHLEDPDSPRLSDAQYGFRR 546
Query: 143 GHSTISALLKVT-------GDIRVGLEESKITILVLVDFSNAFNT 30
G ST SA+ +V R + + ++V +D NAFNT
Sbjct: 547 GRSTFSAIQRVVDAGRRAKSFRRTNHRDKRCLMVVALDICNAFNT 591
>M93690-2|AAA29363.1| 1212|Anopheles gambiae unknown protein.
Length = 1212
Score = 52.8 bits (121), Expect = 9e-09
Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 11/161 (6%)
Frame = -2
Query: 479 EIRKVILSIKSN-AVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRRAYVRA 303
E+R + ++ + A G D I + + + L++ FP W+R +
Sbjct: 484 ELRLIASTMPNKKAPGLDGIPNAAVKAAILAYTDVFQALYQSCLETATFPAPWKRQRLVL 543
Query: 302 LPKIPDPSVPN-HFRPISILPFLSKVLEICVHKQLSRFIFNNSLI--SPFQSGFRPGHST 132
LPK P N +RP+ +L L KVLE + +L + + + + S Q GFR G ST
Sbjct: 544 LPKPGKPPGSNGSYRPLCMLDALGKVLEKLILNRLHNHLEDPAAVRLSDRQHGFRRGRST 603
Query: 131 ISALLKV--TGDI-----RVGLEESKITILVLVDFSNAFNT 30
I A+ V G R +++ ++V +D NAFNT
Sbjct: 604 IGAIRTVIEAGQSAMRFRRTNGRDNRFLLVVSMDVKNAFNT 644
>AB090812-2|BAC57900.1| 1173|Anopheles gambiae reverse transcriptase
protein.
Length = 1173
Score = 52.4 bits (120), Expect = 1e-08
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 11/165 (6%)
Frame = -2
Query: 491 VAPSEIRKVILSIK-SNAVGYDNICRRMIITILDCLLPAIYHIINFSLDSGEFPFLWRRA 315
V P E++++ + A G D I + ++ + L++G FP W+R
Sbjct: 435 VTPEELQEIAAHMAIRKAPGLDGIPNAAVKVAIEKYPGVFCRVYQDCLNTGTFPQQWKRQ 494
Query: 314 YVRALPKIPD-PSVPNHFRPISILPFLSKVLEICVHKQLSRFIFN--NSLISPFQSGFRP 144
+ LPK P + +RP+ +L L KVLE + L+R + + + +S Q GFR
Sbjct: 495 RLVLLPKPGKAPGESSSYRPLCMLDALGKVLERLI---LNRHLEDPDSPQLSDAQYGFRR 551
Query: 143 GHSTISAL--LKVTGDI-----RVGLEESKITILVLVDFSNAFNT 30
G STISA+ L G + + + ++V +D NAFNT
Sbjct: 552 GRSTISAIQSLVDAGKASRSFGQTNNRDKRCLMVVALDVRNAFNT 596
>AB090813-2|BAC57902.1| 1099|Anopheles gambiae reverse transcriptase
protein.
Length = 1099
Score = 52.0 bits (119), Expect = 2e-08
Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 10/118 (8%)
Frame = -2
Query: 353 LDSGEFPFLWRRAYVRALPKIPDPS-VPNHFRPISILPFLSKVLEICVHKQLSRFIFN-- 183
L +G FP W+R + +PK PS V +RP+ +L L KVLE + +L F+ +
Sbjct: 460 LVNGTFPAAWKRQRLVLIPKPGKPSGVSCSYRPLCMLDALGKVLERLILNRLHEFLEDPE 519
Query: 182 NSLISPFQSGFRPGHSTISALLKV--TGDI-----RVGLEESKITILVLVDFSNAFNT 30
+ +S Q GFR G STI + +V G R + + ++ +D NAFNT
Sbjct: 520 SPRLSDRQYGFRRGCSTIGLIQRVVEAGQRAMSFGRANRRDKRFLLVAALDVRNAFNT 577
>AB090817-2|BAC57910.1| 1009|Anopheles gambiae reverse transcriptase
protein.
Length = 1009
Score = 51.6 bits (118), Expect = 2e-08
Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Frame = -2
Query: 353 LDSGEFPFLWRRAYVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNS 177
L++ +FP W+R + +PK P P RPI +L K LE + ++L+ I +
Sbjct: 444 LENAKFPDEWKRQRLVLIPKPNKPPGEPGSVRPICLLDGAGKGLERIIVQRLNAHIEEVN 503
Query: 176 LISPFQSGFRPGHSTISALLKVTGDIRVGLEESKIT----ILVLVDFSNAFNT 30
+S Q GFR ST+ A+ +V + V ++ + +V +D +NAFN+
Sbjct: 504 GLSDDQFGFRSRRSTVDAIQRVVDIVSVARSRNRYSGRYCAVVTLDVTNAFNS 556
>AB090819-2|BAC57914.1| 1022|Anopheles gambiae reverse transcriptase
protein.
Length = 1022
Score = 51.2 bits (117), Expect = 3e-08
Identities = 48/162 (29%), Positives = 74/162 (45%), Gaps = 8/162 (4%)
Frame = -2
Query: 491 VAPSEIRKVILSIKSNAV-GYDNICRRMIITILDCLLPAIYH-IINFSLDSGEFPFLWRR 318
V EIR + S+KS V G D I + T + P I+ + LD+G FP W++
Sbjct: 401 VTDEEIRNIGRSLKSRKVPGPDGIPNAALATAM-IEEPTIFKKVYQRCLDTGVFPDNWKK 459
Query: 317 A-YVRALPKIPD-PSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSLISPFQSGFRP 144
V ++PK P RPI ++ ++K LE + +L+ I +S Q GFR
Sbjct: 460 QRLVLSIPKPGKRPGESGSSRPICLIDGVAKGLERVILHRLNNHIERVQGLSENQYGFRK 519
Query: 143 GHSTISALLKVTGDIRVGLEE----SKITILVLVDFSNAFNT 30
G +T A+ KV ++ +V +D NAFN+
Sbjct: 520 GRATTDAIEKVLSIASASRARNRGANRFCAVVTLDVKNAFNS 561
>AB090820-2|BAC57916.1| 1222|Anopheles gambiae reverse transcriptase
protein.
Length = 1222
Score = 44.0 bits (99), Expect = 4e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
Frame = -2
Query: 353 LDSGEFPFLWRRAYVRALPKI-PDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFN-- 183
LD+ FP W++ + +PK P + + FRPI +L KV E + +++ I +
Sbjct: 466 LDNERFPDEWKKQKLALIPKPGKPPGLASSFRPILLLNNPGKVYERLLLSRINDVIEDPE 525
Query: 182 NSLISPFQSGFRPGHSTISALLKV--TGDI-----RVGLEESKITILVLVDFSNAFNT 30
+ ++ Q GFR G ST+ A+ V G R + + ++V +D NAFNT
Sbjct: 526 SPRLAENQYGFRRGRSTVQAIQLVVDAGSHAMSFGRTNNRDKRCLLVVALDVRNAFNT 583
>AB097127-1|BAC82595.1| 1209|Anopheles gambiae reverse transcriptase
protein.
Length = 1209
Score = 35.5 bits (78), Expect = 0.002
Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 2/118 (1%)
Frame = -2
Query: 350 DSGEFPFLWRRAYVRALPKIPDPSVPNHFRPISILPFLSKVLEICVHKQLSRFIFNNSLI 171
DS + P LPK + P +RP++ L L+KVL + +++ N+++
Sbjct: 506 DSRKLPKFITGGVTYFLPKDQNTKNPAKYRPLTCLSNLNKVLSSVITQKVKDHCDTNNVM 565
Query: 170 SPFQSGFRPGHSTISALLKVTGDIRVG--LEESKITILVLVDFSNAFNTVCHDILLSI 3
+ Q+G R + + I VG ++ + + +D+ A+++V H LL +
Sbjct: 566 TEEQTGRRKNTQGCKDQVIIDAVI-VGQAAKKQRNLDMAYIDYKKAYDSVPHSYLLKV 622
>AY578811-1|AAT07316.1| 565|Anopheles gambiae thickveins protein.
Length = 565
Score = 24.2 bits (50), Expect = 3.8
Identities = 9/25 (36%), Positives = 15/25 (60%)
Frame = -2
Query: 284 PSVPNHFRPISILPFLSKVLEICVH 210
P +P ++ IL LSK+++ C H
Sbjct: 513 PPIPQRWQDEDILVVLSKIMQECWH 537
>AY324311-1|AAQ89696.1| 158|Anopheles gambiae insulin-like peptide
5 precursor protein.
Length = 158
Score = 23.4 bits (48), Expect = 6.6
Identities = 14/45 (31%), Positives = 22/45 (48%)
Frame = +1
Query: 376 IAGRRQSRIVIIMRRHMLSYPTALDLMESITFLISEGATGKS*KG 510
IAG + R ++ ++ YP A+D + FL + TGK G
Sbjct: 80 IAGMMEKRTSMVDEGQLVPYPWAIDREVAYAFLRTR-RTGKRRSG 123
Database: mosquito
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 563,979
Number of sequences in database: 2352
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 683,483
Number of Sequences: 2352
Number of extensions: 13271
Number of successful extensions: 51
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34
length of database: 563,979
effective HSP length: 62
effective length of database: 418,155
effective search space used: 66904800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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