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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brS-0537
         (661 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC036112-1|AAH36112.1|  786|Homo sapiens suppressor of var1, 3-l...   131   2e-30
AL596223-2|CAH71499.1|  786|Homo sapiens suppressor of var1, 3-l...   131   2e-30
AF042169-1|AAB97370.1|  786|Homo sapiens putative ATP-dependent ...   131   2e-30
AF257238-1|AAG24545.1| 1150|Homo sapiens membrane-associated gua...    31   4.8  
AY152396-1|AAN73051.1| 1288|Homo sapiens synaptojanin 2A protein.      30   8.4  
AL139330-4|CAI12983.1| 1496|Homo sapiens synaptojanin 2 protein.       30   8.4  
AF318616-1|AAG46036.1| 1496|Homo sapiens synaptojanin 2 protein.       30   8.4  
AF039945-1|AAD02178.1| 1443|Homo sapiens synaptojanin 2B protein.      30   8.4  
AB002346-1|BAA20805.2| 1443|Homo sapiens KIAA0348 protein protein.     30   8.4  

>BC036112-1|AAH36112.1|  786|Homo sapiens suppressor of var1, 3-like 1
            (S. cerevisiae) protein.
          Length = 786

 Score =  131 bits (317), Expect = 2e-30
 Identities = 85/213 (39%), Positives = 115/213 (53%), Gaps = 17/213 (7%)
 Frame = +3

Query: 6    DSLYFMCNTEGFKFLAEMIQHVPLPLRARYVFCCAPINNKLPFVCATFLKVNGETVQSQR 185
            D  YF+CN + FKF AE+IQH+PL LR RYVFC APIN K PFVC++ L+   +  +++ 
Sbjct: 543  DGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEP 602

Query: 186  AHHPELAERHSGVAAAVSYDHTGPRALGICL*RPKLYLWLSYRFPDMFPDVKLVRDMETE 365
                 L  R+         +      L        LYLWLSYRF DMFPD  L+RD++ E
Sbjct: 603  LTFAWL-RRYIKWPLLPPKNIKDLMDLEAVHDVLDLYLWLSYRFMDMFPDASLIRDLQKE 661

Query: 366  LDAIIQQGIFQITRLLRNSEQMIRDEDSGFAIGHGSK------------RVNKMLVGQSM 509
            LD IIQ G+  IT+L++ SE        GF  G  S+            R  K L  ++ 
Sbjct: 662  LDGIIQDGVHNITKLIKMSETHKLLNLEGFPSGSQSRLSGTLKSQARRTRGTKALGSKAT 721

Query: 510  ---GEEKGKLS--ELLVARGLITPQMLKKLQQE 593
                 + G+LS    LV +GL+TP MLK+L++E
Sbjct: 722  EPPSPDAGELSLASRLVQQGLLTPDMLKQLEKE 754



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/57 (49%), Positives = 34/57 (59%)
 Frame = +1

Query: 118 ITSYRSFVLPS*K*MVRQYSRNEPITRNWLSGTVEWPLPSPMTILDLVHLESVFDVL 288
           I   + FV  S     RQYSRNEP+T  WL   ++WPL  P  I DL+ LE+V DVL
Sbjct: 579 INKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVL 635


>AL596223-2|CAH71499.1|  786|Homo sapiens suppressor of var1, 3-like 1
            (S. cerevisiae) protein.
          Length = 786

 Score =  131 bits (317), Expect = 2e-30
 Identities = 85/213 (39%), Positives = 115/213 (53%), Gaps = 17/213 (7%)
 Frame = +3

Query: 6    DSLYFMCNTEGFKFLAEMIQHVPLPLRARYVFCCAPINNKLPFVCATFLKVNGETVQSQR 185
            D  YF+CN + FKF AE+IQH+PL LR RYVFC APIN K PFVC++ L+   +  +++ 
Sbjct: 543  DGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEP 602

Query: 186  AHHPELAERHSGVAAAVSYDHTGPRALGICL*RPKLYLWLSYRFPDMFPDVKLVRDMETE 365
                 L  R+         +      L        LYLWLSYRF DMFPD  L+RD++ E
Sbjct: 603  LTFAWL-RRYIKWPLLPPKNIKDLMDLEAVHDVLDLYLWLSYRFMDMFPDASLIRDLQKE 661

Query: 366  LDAIIQQGIFQITRLLRNSEQMIRDEDSGFAIGHGSK------------RVNKMLVGQSM 509
            LD IIQ G+  IT+L++ SE        GF  G  S+            R  K L  ++ 
Sbjct: 662  LDGIIQDGVHNITKLIKMSETHKLLNLEGFPSGSQSRLSGTLKSQARRTRGTKALGSKAT 721

Query: 510  ---GEEKGKLS--ELLVARGLITPQMLKKLQQE 593
                 + G+LS    LV +GL+TP MLK+L++E
Sbjct: 722  EPPSPDAGELSLASRLVQQGLLTPDMLKQLEKE 754



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/57 (49%), Positives = 34/57 (59%)
 Frame = +1

Query: 118 ITSYRSFVLPS*K*MVRQYSRNEPITRNWLSGTVEWPLPSPMTILDLVHLESVFDVL 288
           I   + FV  S     RQYSRNEP+T  WL   ++WPL  P  I DL+ LE+V DVL
Sbjct: 579 INKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVL 635


>AF042169-1|AAB97370.1|  786|Homo sapiens putative ATP-dependent
            mitochondrial RNA helicase protein.
          Length = 786

 Score =  131 bits (317), Expect = 2e-30
 Identities = 85/213 (39%), Positives = 115/213 (53%), Gaps = 17/213 (7%)
 Frame = +3

Query: 6    DSLYFMCNTEGFKFLAEMIQHVPLPLRARYVFCCAPINNKLPFVCATFLKVNGETVQSQR 185
            D  YF+CN + FKF AE+IQH+PL LR RYVFC APIN K PFVC++ L+   +  +++ 
Sbjct: 543  DGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEP 602

Query: 186  AHHPELAERHSGVAAAVSYDHTGPRALGICL*RPKLYLWLSYRFPDMFPDVKLVRDMETE 365
                 L  R+         +      L        LYLWLSYRF DMFPD  L+RD++ E
Sbjct: 603  LTFAWL-RRYIKWPLLPPKNIKDLMDLEAVHDVLDLYLWLSYRFMDMFPDASLIRDLQKE 661

Query: 366  LDAIIQQGIFQITRLLRNSEQMIRDEDSGFAIGHGSK------------RVNKMLVGQSM 509
            LD IIQ G+  IT+L++ SE        GF  G  S+            R  K L  ++ 
Sbjct: 662  LDGIIQDGVHNITKLIKMSETHKLLNLEGFPSGSQSRLSGTLKSQARRTRGTKALGSKAT 721

Query: 510  ---GEEKGKLS--ELLVARGLITPQMLKKLQQE 593
                 + G+LS    LV +GL+TP MLK+L++E
Sbjct: 722  EPPSPDAGELSLASRLVQQGLLTPDMLKQLEKE 754



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/57 (49%), Positives = 34/57 (59%)
 Frame = +1

Query: 118 ITSYRSFVLPS*K*MVRQYSRNEPITRNWLSGTVEWPLPSPMTILDLVHLESVFDVL 288
           I   + FV  S     RQYSRNEP+T  WL   ++WPL  P  I DL+ LE+V DVL
Sbjct: 579 INKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVL 635


>AF257238-1|AAG24545.1| 1150|Homo sapiens membrane-associated
           guanylate kinase MAGI3 protein.
          Length = 1150

 Score = 30.7 bits (66), Expect = 4.8
 Identities = 12/20 (60%), Positives = 13/20 (65%)
 Frame = -1

Query: 91  RARSGNGTCCIISAKNLNPS 32
           R   G GTCCI+S K  NPS
Sbjct: 49  REEPGGGTCCIVSGKAPNPS 68


>AY152396-1|AAN73051.1| 1288|Homo sapiens synaptojanin 2A protein.
          Length = 1288

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +3

Query: 384 QGIFQITRLLRNSEQMIRDEDSGFAIGHGSKRVNKMLVGQSMGEEKGKLSELLV--ARGL 557
           +G  ++ +L   +  M R   S F  G   + +  +LVG   GEE      +L+     L
Sbjct: 449 EGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL 508

Query: 558 ITPQMLKKLQQELS 599
           +TP++LK + +  S
Sbjct: 509 VTPRILKAMTERQS 522


>AL139330-4|CAI12983.1| 1496|Homo sapiens synaptojanin 2 protein.
          Length = 1496

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +3

Query: 384 QGIFQITRLLRNSEQMIRDEDSGFAIGHGSKRVNKMLVGQSMGEEKGKLSELLV--ARGL 557
           +G  ++ +L   +  M R   S F  G   + +  +LVG   GEE      +L+     L
Sbjct: 449 EGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL 508

Query: 558 ITPQMLKKLQQELS 599
           +TP++LK + +  S
Sbjct: 509 VTPRILKAMTERQS 522


>AF318616-1|AAG46036.1| 1496|Homo sapiens synaptojanin 2 protein.
          Length = 1496

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +3

Query: 384 QGIFQITRLLRNSEQMIRDEDSGFAIGHGSKRVNKMLVGQSMGEEKGKLSELLV--ARGL 557
           +G  ++ +L   +  M R   S F  G   + +  +LVG   GEE      +L+     L
Sbjct: 449 EGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL 508

Query: 558 ITPQMLKKLQQELS 599
           +TP++LK + +  S
Sbjct: 509 VTPRILKAMTERQS 522


>AF039945-1|AAD02178.1| 1443|Homo sapiens synaptojanin 2B protein.
          Length = 1443

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +3

Query: 384 QGIFQITRLLRNSEQMIRDEDSGFAIGHGSKRVNKMLVGQSMGEEKGKLSELLV--ARGL 557
           +G  ++ +L   +  M R   S F  G   + +  +LVG   GEE      +L+     L
Sbjct: 396 EGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL 455

Query: 558 ITPQMLKKLQQELS 599
           +TP++LK + +  S
Sbjct: 456 VTPRILKAMTERQS 469


>AB002346-1|BAA20805.2| 1443|Homo sapiens KIAA0348 protein protein.
          Length = 1443

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +3

Query: 384 QGIFQITRLLRNSEQMIRDEDSGFAIGHGSKRVNKMLVGQSMGEEKGKLSELLV--ARGL 557
           +G  ++ +L   +  M R   S F  G   + +  +LVG   GEE      +L+     L
Sbjct: 396 EGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL 455

Query: 558 ITPQMLKKLQQELS 599
           +TP++LK + +  S
Sbjct: 456 VTPRILKAMTERQS 469


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,631,151
Number of Sequences: 237096
Number of extensions: 1960875
Number of successful extensions: 4793
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 4664
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4790
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7422585720
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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