BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= brS-0521 (656 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 217 2e-56 D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 217 2e-56 BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 217 2e-56 AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 217 2e-56 X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 214 2e-55 DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 214 2e-55 BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 214 2e-55 BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 214 2e-55 AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 214 2e-55 L42451-1|AAC42010.1| 407|Homo sapiens pyruvate dehydrogenase ki... 30 8.3 BC063137-1|AAH63137.1| 407|Homo sapiens pyruvate dehydrogenase ... 30 8.3 BC040478-1|AAH40478.1| 407|Homo sapiens pyruvate dehydrogenase ... 30 8.3 BC005811-1|AAH05811.1| 407|Homo sapiens pyruvate dehydrogenase ... 30 8.3 >X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransferase protein. Length = 395 Score = 217 bits (531), Expect = 2e-56 Identities = 99/143 (69%), Positives = 118/143 (82%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAG+TGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVKAGLC Sbjct: 252 IGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPLI 431 Q+T+ YGHFGR+ FPWE P+ L+ Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394 >D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synthetase protein. Length = 395 Score = 217 bits (531), Expect = 2e-56 Identities = 99/143 (69%), Positives = 118/143 (82%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAG+TGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVKAGLC Sbjct: 252 IGGPQGDAGVTGRKIIVDTYAAWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPLI 431 Q+T+ YGHFGR+ FPWE P+ L+ Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394 >BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltransferase I, alpha protein. Length = 395 Score = 217 bits (531), Expect = 2e-56 Identities = 99/143 (69%), Positives = 118/143 (82%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAG+TGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVKAGLC Sbjct: 252 IGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPLI 431 Q+T+ YGHFGR+ FPWE P+ L+ Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394 >AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltransferase I, alpha protein. Length = 395 Score = 217 bits (531), Expect = 2e-56 Identities = 99/143 (69%), Positives = 118/143 (82%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAG+TGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVKAGLC Sbjct: 252 IGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPLI 431 Q+T+ YGHFGR+ FPWE P+ L+ Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394 >X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synthetase protein. Length = 395 Score = 214 bits (523), Expect = 2e-55 Identities = 99/142 (69%), Positives = 115/142 (80%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAGLTGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVK GLC Sbjct: 252 IGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IV+KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPL 428 QRT+ YGHFGR FPWE PK L Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393 >DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltransferase II protein. Length = 395 Score = 214 bits (523), Expect = 2e-55 Identities = 99/142 (69%), Positives = 115/142 (80%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAGLTGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVK GLC Sbjct: 252 IGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IV+KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPL 428 QRT+ YGHFGR FPWE PK L Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393 >BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltransferase II, alpha protein. Length = 395 Score = 214 bits (523), Expect = 2e-55 Identities = 99/142 (69%), Positives = 115/142 (80%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAGLTGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVK GLC Sbjct: 252 IGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IV+KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPL 428 QRT+ YGHFGR FPWE PK L Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393 >BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltransferase II, alpha protein. Length = 395 Score = 214 bits (523), Expect = 2e-55 Identities = 99/142 (69%), Positives = 115/142 (80%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAGLTGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVK GLC Sbjct: 252 IGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IV+KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPL 428 QRT+ YGHFGR FPWE PK L Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393 >AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. Length = 395 Score = 214 bits (523), Expect = 2e-55 Identities = 99/142 (69%), Positives = 115/142 (80%) Frame = +3 Query: 3 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKAGLC 182 IGGPQ DAGLTGRKIIVDTY KD+TKVDRSAAYAARWVAKSLVK GLC Sbjct: 252 IGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLC 311 Query: 183 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIY 362 RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IV+KNFDLRPG IV++L+L+ PIY Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371 Query: 363 QRTSTYGHFGRAGFPWESPKPL 428 QRT+ YGHFGR FPWE PK L Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393 >L42451-1|AAC42010.1| 407|Homo sapiens pyruvate dehydrogenase kinase protein. Length = 407 Score = 29.9 bits (64), Expect = 8.3 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Frame = +3 Query: 144 RWVAKSLVKAGLCRRCMVQVAYAIGVAEPLSITVF-DYGTSHKTQQQLLSIVQKNFDLRP 320 RWV L A L ++ PLS+ F D+G+S+ ++ + +++ +R Sbjct: 2 RWVWALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRL 61 Query: 321 GKIVKELNL 347 I+KE+NL Sbjct: 62 ANIMKEINL 70 >BC063137-1|AAH63137.1| 407|Homo sapiens pyruvate dehydrogenase kinase, isozyme 2 protein. Length = 407 Score = 29.9 bits (64), Expect = 8.3 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Frame = +3 Query: 144 RWVAKSLVKAGLCRRCMVQVAYAIGVAEPLSITVF-DYGTSHKTQQQLLSIVQKNFDLRP 320 RWV L A L ++ PLS+ F D+G+S+ ++ + +++ +R Sbjct: 2 RWVWALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRL 61 Query: 321 GKIVKELNL 347 I+KE+NL Sbjct: 62 ANIMKEINL 70 >BC040478-1|AAH40478.1| 407|Homo sapiens pyruvate dehydrogenase kinase, isozyme 2 protein. Length = 407 Score = 29.9 bits (64), Expect = 8.3 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Frame = +3 Query: 144 RWVAKSLVKAGLCRRCMVQVAYAIGVAEPLSITVF-DYGTSHKTQQQLLSIVQKNFDLRP 320 RWV L A L ++ PLS+ F D+G+S+ ++ + +++ +R Sbjct: 2 RWVWALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRL 61 Query: 321 GKIVKELNL 347 I+KE+NL Sbjct: 62 ANIMKEINL 70 >BC005811-1|AAH05811.1| 407|Homo sapiens pyruvate dehydrogenase kinase, isozyme 2 protein. Length = 407 Score = 29.9 bits (64), Expect = 8.3 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Frame = +3 Query: 144 RWVAKSLVKAGLCRRCMVQVAYAIGVAEPLSITVF-DYGTSHKTQQQLLSIVQKNFDLRP 320 RWV L A L ++ PLS+ F D+G+S+ ++ + +++ +R Sbjct: 2 RWVWALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRL 61 Query: 321 GKIVKELNL 347 I+KE+NL Sbjct: 62 ANIMKEINL 70 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 95,499,493 Number of Sequences: 237096 Number of extensions: 2119176 Number of successful extensions: 4582 Number of sequences better than 10.0: 13 Number of HSP's better than 10.0 without gapping: 4359 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4582 length of database: 76,859,062 effective HSP length: 87 effective length of database: 56,231,710 effective search space used: 7366354010 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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