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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brS-0374
         (746 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY736034-1|AAU50678.1|  478|Homo sapiens F-box and WD-40 repeat ...    36   0.12 
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin...    35   0.27 
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin...    35   0.27 
AK127729-1|BAC87105.1|  870|Homo sapiens protein ( Homo sapiens ...    35   0.27 
BC063415-1|AAH63415.1|  412|Homo sapiens F-box and WD repeat dom...    32   1.9  
AL627424-2|CAI41027.1|  412|Homo sapiens F-box and WD repeat dom...    32   1.9  
AL627144-3|CAI12232.1|  412|Homo sapiens F-box and WD repeat dom...    32   1.9  
AF281859-1|AAG22739.1|  412|Homo sapiens dactylin protein.             32   1.9  
AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein.              30   7.7  
AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein.            30   7.7  

>AY736034-1|AAU50678.1|  478|Homo sapiens F-box and WD-40 repeat
           containing protein 9 protein.
          Length = 478

 Score = 36.3 bits (80), Expect = 0.12
 Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = +2

Query: 119 TKVKMEESPALLNLPAEMIILIIKYLDTPTVYNIYN-TCKPLREIITQGVVKNLK 280
           ++V     P LL+LP E+++ I  YLD   V ++ +  C  LR++++  V   L+
Sbjct: 69  SRVSAVSEPGLLSLPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLR 123


>BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kinase 2
            protein.
          Length = 2527

 Score = 35.1 bits (77), Expect = 0.27
 Identities = 31/130 (23%), Positives = 54/130 (41%)
 Frame = +2

Query: 320  TDFFKAVAYSLKDLSLSGMHDLTKTKLIQAVRHLKSLQTLDVTYTDISICDLLDIHPLCP 499
            T F + +  +LK L+   +H    T     +  +  +  LDV+  DI    +LD    CP
Sbjct: 1024 TSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKCP 1083

Query: 500  TVKNIAINYIFGKLGMTRMTPEFIEACQNLLAKFENIHFVGSSINLMYSNFSIHVLNKTK 679
            T+K   ++Y         +T + +E  + L+ +   I  + S + L      I  L+K  
Sbjct: 1084 TLKQFNLSYNQLSFVPENLT-DVVEKLEQLILEGNKISGICSPLRL--KELKILNLSKNH 1140

Query: 680  LQSLKYTISE 709
            + SL     E
Sbjct: 1141 ISSLSENFLE 1150


>AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kinase 2
            protein.
          Length = 2527

 Score = 35.1 bits (77), Expect = 0.27
 Identities = 31/130 (23%), Positives = 54/130 (41%)
 Frame = +2

Query: 320  TDFFKAVAYSLKDLSLSGMHDLTKTKLIQAVRHLKSLQTLDVTYTDISICDLLDIHPLCP 499
            T F + +  +LK L+   +H    T     +  +  +  LDV+  DI    +LD    CP
Sbjct: 1024 TSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKCP 1083

Query: 500  TVKNIAINYIFGKLGMTRMTPEFIEACQNLLAKFENIHFVGSSINLMYSNFSIHVLNKTK 679
            T+K   ++Y         +T + +E  + L+ +   I  + S + L      I  L+K  
Sbjct: 1084 TLKQFNLSYNQLSFVPENLT-DVVEKLEQLILEGNKISGICSPLRL--KELKILNLSKNH 1140

Query: 680  LQSLKYTISE 709
            + SL     E
Sbjct: 1141 ISSLSENFLE 1150


>AK127729-1|BAC87105.1|  870|Homo sapiens protein ( Homo sapiens cDNA
            FLJ45829 fis, clone NT2RP8006452. ).
          Length = 870

 Score = 35.1 bits (77), Expect = 0.27
 Identities = 31/130 (23%), Positives = 54/130 (41%)
 Frame = +2

Query: 320  TDFFKAVAYSLKDLSLSGMHDLTKTKLIQAVRHLKSLQTLDVTYTDISICDLLDIHPLCP 499
            T F + +  +LK L+   +H    T     +  +  +  LDV+  DI    +LD    CP
Sbjct: 623  TSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKCP 682

Query: 500  TVKNIAINYIFGKLGMTRMTPEFIEACQNLLAKFENIHFVGSSINLMYSNFSIHVLNKTK 679
            T+K   ++Y         +T + +E  + L+ +   I  + S + L      I  L+K  
Sbjct: 683  TLKQFNLSYNQLSFVPENLT-DVVEKLEQLILEGNKISGICSPLRL--KELKILNLSKNH 739

Query: 680  LQSLKYTISE 709
            + SL     E
Sbjct: 740  ISSLSENFLE 749


>BC063415-1|AAH63415.1|  412|Homo sapiens F-box and WD repeat domain
           containing 4 protein.
          Length = 412

 Score = 32.3 bits (70), Expect = 1.9
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = +2

Query: 143 PALLNLPAEMIILIIKYLDTPTVYNIYNTCKPLREIITQGVVKNLKFSLNILSTADSLKT 322
           PAL  LP E+++LI  YLD   +  +   C+ LR   +  ++       ++ S    L T
Sbjct: 26  PALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGT 85

Query: 323 DFFKAV 340
           D   +V
Sbjct: 86  DLMTSV 91


>AL627424-2|CAI41027.1|  412|Homo sapiens F-box and WD repeat domain
           containing 4 protein.
          Length = 412

 Score = 32.3 bits (70), Expect = 1.9
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = +2

Query: 143 PALLNLPAEMIILIIKYLDTPTVYNIYNTCKPLREIITQGVVKNLKFSLNILSTADSLKT 322
           PAL  LP E+++LI  YLD   +  +   C+ LR   +  ++       ++ S    L T
Sbjct: 26  PALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGT 85

Query: 323 DFFKAV 340
           D   +V
Sbjct: 86  DLMTSV 91


>AL627144-3|CAI12232.1|  412|Homo sapiens F-box and WD repeat domain
           containing 4 protein.
          Length = 412

 Score = 32.3 bits (70), Expect = 1.9
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = +2

Query: 143 PALLNLPAEMIILIIKYLDTPTVYNIYNTCKPLREIITQGVVKNLKFSLNILSTADSLKT 322
           PAL  LP E+++LI  YLD   +  +   C+ LR   +  ++       ++ S    L T
Sbjct: 26  PALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGT 85

Query: 323 DFFKAV 340
           D   +V
Sbjct: 86  DLMTSV 91


>AF281859-1|AAG22739.1|  412|Homo sapiens dactylin protein.
          Length = 412

 Score = 32.3 bits (70), Expect = 1.9
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = +2

Query: 143 PALLNLPAEMIILIIKYLDTPTVYNIYNTCKPLREIITQGVVKNLKFSLNILSTADSLKT 322
           PAL  LP E+++LI  YLD   +  +   C+ LR   +  ++       ++ S    L T
Sbjct: 26  PALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGT 85

Query: 323 DFFKAV 340
           D   +V
Sbjct: 86  DLMTSV 91


>AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein.
          Length = 8749

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
 Frame = +2

Query: 356  DLSLSGMHDLTKTKLIQAVRHLKSLQTLDVTYTDI--SICDL 475
            DL  S    L++ + I+ V+H ++LQ    TY D+  S+CDL
Sbjct: 3987 DLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDL 4028


>AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein.
          Length = 8797

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
 Frame = +2

Query: 356  DLSLSGMHDLTKTKLIQAVRHLKSLQTLDVTYTDI--SICDL 475
            DL  S    L++ + I+ V+H ++LQ    TY D+  S+CDL
Sbjct: 4058 DLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDL 4099


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,253,872
Number of Sequences: 237096
Number of extensions: 1770469
Number of successful extensions: 10843
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10694
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10843
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8959138240
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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