Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-0332
(759 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch... 335 6e-91
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ... 316 3e-85
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ... 312 8e-84
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ... 264 2e-69
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial... 263 3e-69
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ... 247 2e-64
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi... 241 2e-62
UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate... 221 1e-56
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ... 79 3e-26
UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma j... 113 6e-24
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase... 108 2e-22
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase... 100 3e-20
UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1; ... 97 5e-19
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3... 88 3e-16
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro... 83 1e-14
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot... 53 9e-06
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B... 51 3e-05
UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza sa... 43 0.009
UniRef50_Q09277 Cluster: Putative uncharacterized protein F40H6.... 35 2.5
UniRef50_A0KSD7 Cluster: Putative uncharacterized protein; n=2; ... 34 4.4
UniRef50_Q0HEG1 Cluster: Conserved hypothetical biogenesis prote... 33 7.7
UniRef50_O17998 Cluster: Putative uncharacterized protein; n=2; ... 33 7.7
>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
sapiens (Human)
Length = 452
Score = 335 bits (824), Expect = 6e-91
Identities = 155/220 (70%), Positives = 179/220 (81%), Gaps = 1/220 (0%)
Frame = +1
Query: 103 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 282
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 283 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 462
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 463 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 639
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 640 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
n=6; core eudicotyledons|Rep: Isocitrate
dehydrogenase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 485
Score = 316 bits (777), Expect = 3e-85
Identities = 144/217 (66%), Positives = 174/217 (80%), Gaps = 1/217 (0%)
Frame = +1
Query: 112 GTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTI 291
G + R+ P+VEMDGDEMTR+IW+ IKE+LI PY+ +D YFDLG+ +RDATDD+VT+
Sbjct: 71 GGSDRIQVQNPIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTV 130
Query: 292 DSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIP 471
+SA A LK+NV IKCATITPDE RV+EF LK MW SPNGTIRNIL GTVFREPI+C +IP
Sbjct: 131 ESAEAALKYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIP 190
Query: 472 RVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRV-LYDFKTPGVA 648
R+VPGW KPI IGRHA GDQY+A D V+ PGK+++V+ +DG + +YDFK PGVA
Sbjct: 191 RLVPGWEKPICIGRHAFGDQYRATDTVIKGPGKLKMVFVPEDGNAPVELDVYDFKGPGVA 250
Query: 649 MGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
+ MYN DESIR+FA SS +AL KKWPLYLSTKNTIL
Sbjct: 251 LAMYNVDESIRAFAESSMAMALTKKWPLYLSTKNTIL 287
>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 410
Score = 312 bits (765), Expect = 8e-84
Identities = 141/213 (66%), Positives = 170/213 (79%)
Frame = +1
Query: 121 KRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSA 300
+++ A P+VEMDGDEMTR+IW IK++LI P+V++D YFDLGLPHRDATDD+VTI+SA
Sbjct: 4 EKIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGLPHRDATDDKVTIESA 63
Query: 301 HAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVV 480
A K+NV IKCATITPDE RV EF LK+MW SPNGTIRNIL GTVFREPI+C+++P++V
Sbjct: 64 EATKKYNVAIKCATITPDEGRVTEFGLKQMWRSPNGTIRNILNGTVFREPIICKNVPKLV 123
Query: 481 PGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDFKTPGVAMGMY 660
PGWTKPI IGRHA GDQY+A D V+ PGK+ + + +DG TE V GVAM MY
Sbjct: 124 PGWTKPICIGRHAFGDQYRATDAVIKGPGKLTMTFEGKDGKTETEVFTFTGEGGVAMAMY 183
Query: 661 NTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
NTDESIR+FA +S A +KKWPLYLSTKNTIL
Sbjct: 184 NTDESIRAFADASMNTAYEKKWPLYLSTKNTIL 216
>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
Eukaryota|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 475
Score = 264 bits (647), Expect = 2e-69
Identities = 131/223 (58%), Positives = 159/223 (71%), Gaps = 18/223 (8%)
Frame = +1
Query: 145 VVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNV 324
V GDEMTR+IW IK++LIFP++ +D Y+DLGLP+RDAT D+VTI+SA A LK+NV
Sbjct: 37 VTRNSGDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGLPNRDATGDKVTIESAEATLKYNV 96
Query: 325 GIKCATITP------------------DEQRVEEFKLKKMWLSPNGTIRNILGGTVFREP 450
IKCATITP DE RV+EF L MW SPNGTIRNIL GTVFREP
Sbjct: 97 AIKCATITPVLDTQFKFDFGRTIHEPTDEGRVKEFNLSAMWKSPNGTIRNILNGTVFREP 156
Query: 451 ILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDF 630
I+C++IPR+VPGW KPI IGRHA GDQY+A D V+ PGK++LV+ ++ E V
Sbjct: 157 IICKNIPRLVPGWIKPICIGRHAFGDQYRATDTVIKGPGKLKLVFDGREEQIELDVFNFT 216
Query: 631 KTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
GVA+ MYNTDESI +FA +S +A QK+WPLYLSTKNTIL
Sbjct: 217 GAGGVALSMYNTDESIWAFAEASMNMAYQKRWPLYLSTKNTIL 259
>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
mitochondrial - Aspergillus terreus (strain NIH 2624)
Length = 466
Score = 263 bits (645), Expect = 3e-69
Identities = 122/171 (71%), Positives = 145/171 (84%), Gaps = 1/171 (0%)
Frame = +1
Query: 250 GLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILG 429
G+ +RD TDD+VT+++A AI K+ VG+KCATITPDE RVEEFKLKKMWLSPNGTIRNILG
Sbjct: 101 GIEYRDQTDDKVTVEAAEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILG 160
Query: 430 GTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE 609
GTVFREPI+ +IPR+VPGWTKPI+IGRHA GDQY+A D V+P PGK+ELVYT +G E
Sbjct: 161 GTVFREPIVIPAIPRLVPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPANGQPE 220
Query: 610 RRVLYDFKT-PGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
+YDF++ GVAM MYNTD+SIR FAHSSF++AL K PLY+STKNTIL
Sbjct: 221 SVQVYDFQSGGGVAMSMYNTDDSIRGFAHSSFKMALLKGLPLYMSTKNTIL 271
>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 247 bits (605), Expect = 2e-64
Identities = 113/212 (53%), Positives = 151/212 (71%)
Frame = +1
Query: 121 KRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSA 300
+++ P+VEMDGDEMTRI+W IK+ L+ P++ ++ Y+DLGL +R+ TDDQVTID+A
Sbjct: 17 EKIQMTTPLVEMDGDEMTRILWKMIKDELLLPFIDLNTEYYDLGLNYRNETDDQVTIDAA 76
Query: 301 HAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVV 480
A K+ V +KCATITP+ R++E+ LKKM+ SPNGTIR IL GTVFR PI+ + I V
Sbjct: 77 EATKKYGVAVKCATITPNHARMDEYDLKKMYKSPNGTIRAILDGTVFRAPIVVKGIEPCV 136
Query: 481 PGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDFKTPGVAMGMY 660
W KPI + RHA+GD YK + + KPGKVELVYT++DG +R ++ +FK PGVAMGM+
Sbjct: 137 RNWKKPITLARHAYGDIYKNTEMYIDKPGKVELVYTSEDGEEKRSLVQEFKAPGVAMGMH 196
Query: 661 NTDESIRSFAHSSFQVALQKKWPLYLSTKNTI 756
N SI SFA S F AL K ++ K+TI
Sbjct: 197 NMTASIESFARSCFNYALDTKQDVWFGAKDTI 228
>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
kluyveri DSM 555
Length = 401
Score = 241 bits (589), Expect = 2e-62
Identities = 111/205 (54%), Positives = 150/205 (73%)
Frame = +1
Query: 142 PVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHN 321
P+VEMDGDEMTRIIW IKE L+ PY+ + Y+DLGL R+ T+D++TI++A+AI K+
Sbjct: 10 PLVEMDGDEMTRIIWKMIKELLLEPYIDLKTEYYDLGLVKRNETNDEITIEAANAIKKYG 69
Query: 322 VGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPI 501
VG+KCATITP+ +RV+E+ LK MW SPNGTIR IL GTVFR PI+ SI ++ W KPI
Sbjct: 70 VGVKCATITPNAKRVKEYNLKSMWKSPNGTIRAILDGTVFRTPIIVNSIRPLMRTWEKPI 129
Query: 502 VIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDFKTPGVAMGMYNTDESIR 681
+ RHA+GD Y+ ++ V +PGK+ELV+T++ G R+ L+ F PGV MGM+N D+SI
Sbjct: 130 TVARHAYGDVYRDVEYKVEEPGKMELVFTSEKGEETRQTLHVFNGPGVVMGMHNLDKSIE 189
Query: 682 SFAHSSFQVALQKKWPLYLSTKNTI 756
SFA S F AL L+ ++K+TI
Sbjct: 190 SFARSCFNYALDMNQNLWFASKDTI 214
>UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate
dehydrogenase 1 (NADP+), soluble; n=2; Danio rerio|Rep:
PREDICTED: similar to Isocitrate dehydrogenase 1
(NADP+), soluble - Danio rerio
Length = 206
Score = 221 bits (541), Expect = 1e-56
Identities = 96/134 (71%), Positives = 119/134 (88%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
+ A VVEM GDEMTR+IW IKE+LIFPY+++D +DLG+ +RDATDD+VT+++A A+
Sbjct: 12 IKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTVEAAEAV 71
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
++NVGIKCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+VPGW
Sbjct: 72 RRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIPRLVPGW 131
Query: 490 TKPIVIGRHAHGDQ 531
KPI+IGRHAHGDQ
Sbjct: 132 IKPIIIGRHAHGDQ 145
>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 371
Score = 79.0 bits (186), Expect(2) = 3e-26
Identities = 35/47 (74%), Positives = 40/47 (85%)
Frame = +1
Query: 619 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
+Y+FK PGVA+ MYN DESIR+FA SS +AL KKWPLYLSTKNTIL
Sbjct: 44 VYNFKGPGVALSMYNVDESIRAFAESSMAMALSKKWPLYLSTKNTIL 90
Score = 62.9 bits (146), Expect(2) = 3e-26
Identities = 27/40 (67%), Positives = 33/40 (82%), Gaps = 2/40 (5%)
Frame = +1
Query: 388 MWLSPNGTIRNILGGTVFREPILCQSIPRV--VPGWTKPI 501
MW SPNGTIRNIL GTVFREPILC+++PR+ VP +P+
Sbjct: 1 MWRSPNGTIRNILNGTVFREPILCKNVPRILSVPDGAEPV 40
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/30 (76%), Positives = 26/30 (86%)
Frame = +1
Query: 670 ESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
+SIR+FA SS +AL KKWPLYLSTKNTIL
Sbjct: 157 QSIRAFAESSMAMALSKKWPLYLSTKNTIL 186
>UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09598 protein - Schistosoma
japonicum (Blood fluke)
Length = 129
Score = 113 bits (271), Expect = 6e-24
Identities = 59/87 (67%), Positives = 66/87 (75%)
Frame = -2
Query: 452 IGSRNTVPPKMLRIVPFGLSHIFFNLNSSTLCSSGVIVAHLMPTLCFRMACAESMVT*SS 273
+GSR TVPP++LRIVPFG SHIFF LNS T CSSGV+VAHL+PTL F +A A S+VT S
Sbjct: 1 MGSRKTVPPRILRIVPFGDSHIFFKLNSLTRCSSGVMVAHLIPTLYFLIASAPSIVTWSL 60
Query: 272 VASRCGRPKSK*RQSTLTYGNISLSLI 192
V SR GRPKSK QST GNIS I
Sbjct: 61 VRSRLGRPKSKYLQSTSINGNISCCFI 87
>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
isocitrate dehydrogenase protein - Rhizobium etli
(strain CFN 42 / ATCC 51251)
Length = 437
Score = 108 bits (259), Expect = 2e-22
Identities = 67/203 (33%), Positives = 105/203 (51%)
Frame = -1
Query: 759 QNGILRGQV*RPFFL*SYLKTGMGKGPNRFVGIVHAHSNAWSFKII*YTPLSRTILCSVN 580
++G+L QV RPF + G G+ +RFV +VH H NA + ++ +
Sbjct: 209 EDGVLGRQVDRPFAHQAVHHRGAGEFADRFVEVVHGHGNAGARRVEDLLLDDGAVFTDEL 268
Query: 579 EFNLSGFRYNKILRLVLVAVRMTAYHNRFRPTRHNPRDTLTQYRFAEYCTAQNVTDRSVR 400
+ L+ ++ VLVA +TA +R RP + R+ R AE A+NV+DR+VR
Sbjct: 269 DRQLALAGELEVGCAVLVAESVTADDDRLRPAGNEARNVAADDRLAEDDAAENVSDRAVR 328
Query: 399 T*PHFLQLELFYSLFIRCDSSAFDAHIML*NGMR*VDGDLIISGVTMREAQVKVKTIHLN 220
PHFL++E + FIR D A D + +G+ VD L++ GV + + +V + I +
Sbjct: 329 ALPHFLEIEFLDAGFIRRDRCALDTDAVFLDGVGGVDRHLVVGGVAIFDREVVIVDIEVE 388
Query: 219 IWKYQPLFDLSPDDACHLITIHL 151
I Q + D PDDACH I + +
Sbjct: 389 IRMDQLILDELPDDACHFIAVEI 411
>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
isocitrate dehydrogenase protein - Sagittula stellata
E-37
Length = 459
Score = 100 bits (240), Expect = 3e-20
Identities = 67/203 (33%), Positives = 100/203 (49%)
Frame = -1
Query: 759 QNGILRGQV*RPFFL*SYLKTGMGKGPNRFVGIVHAHSNAWSFKII*YTPLSRTILCSVN 580
+NG+L QV RP + ++ G GK +R V +VHAH + +++ +
Sbjct: 240 ENGVLGRQVHRPAQRQTVVQRGAGKVADRLVLVVHAHVDPGIGRVVDLALDHLAVGAFPF 299
Query: 579 EFNLSGFRYNKILRLVLVAVRMTAYHNRFRPTRHNPRDTLTQYRFAEYCTAQNVTDRSVR 400
L+ +I LVLVA + A+H+ P RH R R AE AQ+V DR+V
Sbjct: 300 HRQLARRGEVEIRGLVLVAEGVPAHHDGRGPARHEARHVAADDRLAEDDAAQDVADRAVG 359
Query: 399 T*PHFLQLELFYSLFIRCDSSAFDAHIML*NGMR*VDGDLIISGVTMREAQVKVKTIHLN 220
PH L+ E +L +R D AFD L VDGDL+ V + + ++ VK + +
Sbjct: 360 RLPHLLETEFLDTLLVRGDRRAFDRDANLLRLFGGVDGDLVPGPVPLLDPEIVVKQVQVE 419
Query: 219 IWKYQPLFDLSPDDACHLITIHL 151
+ + Q D SP DA HL+ +HL
Sbjct: 420 VRQDQLFLDESPHDAGHLVAVHL 442
>UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 141
Score = 96.7 bits (230), Expect = 5e-19
Identities = 56/91 (61%), Positives = 64/91 (70%)
Frame = -2
Query: 422 MLRIVPFGLSHIFFNLNSSTLCSSGVIVAHLMPTLCFRMACAESMVT*SSVASRCGRPKS 243
MLRIVP G HIF +LNS T SS VIVAHL+PTLC R+A A S VT S VASR +S
Sbjct: 1 MLRIVPLGEGHIFLSLNSLTRASSAVIVAHLIPTLCSRIAQAASKVTQSLVASRFSIERS 60
Query: 242 K*RQSTLTYGNISLSLILAQMMRVISSPSIS 150
+ S GN+SLSLI+ QM+RVISSPS S
Sbjct: 61 QYLISAEINGNMSLSLIIFQMIRVISSPSKS 91
>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
Ostreococcus tauri
Length = 429
Score = 87.8 bits (208), Expect = 3e-16
Identities = 70/221 (31%), Positives = 105/221 (47%), Gaps = 7/221 (3%)
Frame = +1
Query: 115 TAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLY-FDLGLPHRDATDDQVTI 291
TA + A P+V + G+EMT + I+ R I P V V FDL +RD T+D+V
Sbjct: 21 TASSKITAAPMVYVRGEEMTAYVMDLIRSRWIEPRVDVGGWETFDLRAKNRDDTEDRVLR 80
Query: 292 DSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGG-TVFREPILCQSI 468
D A + K T+TP +V+ L+K W SPNG +R G T+ R+ I I
Sbjct: 81 DVIEAGKRIKAIFKEPTVTPTADQVKRLGLRKSWGSPNGAMRRGWNGITISRDTI---HI 137
Query: 469 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDG-TTERRVLYDFK---- 633
V G+ KP++ RHA G +Y A V K GK+ +T +G + V+ D +
Sbjct: 138 DGVELGYKKPVLFERHAVGGEYSAGYKNVGK-GKLTTTFTPSEGPDAGKTVVVDEREIVD 196
Query: 634 TPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTI 756
+ +N +++ A F L+ K Y+ TK T+
Sbjct: 197 EEAAVVTYHNPYDNVHDLARFFFGRCLEAKVTPYVVTKKTV 237
>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
Marinobacter sp. ELB17
Length = 582
Score = 82.6 bits (195), Expect = 1e-14
Identities = 56/224 (25%), Positives = 107/224 (47%), Gaps = 12/224 (5%)
Frame = +1
Query: 124 RVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAH 303
++ P+V + GDEM ++ + +I ++ + + ++ + DL HR T+ QV ++
Sbjct: 4 KIQVESPLVILHGDEMAQVAFEEILKKFVTTRLAIELIEIDLSAEHRFLTNGQVIFEAIE 63
Query: 304 AILKHNVGIKCATITPDEQRVEEFKLKKMWL-----------SPNGTIRNILGGTVFREP 450
A+ K+ VG+K A +T + ++++ K L SPNG IR +GG + RE
Sbjct: 64 ALKKYGVGVKNAGMTVNREQLDAMLEKHPELSQSRLDPLATKSPNGAIRKGIGGNITRED 123
Query: 451 ILCQSIPRVVPGW-TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYD 627
I Q++ P W + I + +G + + + G V+L++ + G D
Sbjct: 124 IQFQNLRVRKPDWIDRDIDVDTMDNGGIKDSYNELSSSTGVVKLLFVGKSGNPVELHRRD 183
Query: 628 FKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
K + N ++++AH FQ A+ +K YL K+T++
Sbjct: 184 VKKGDPWLLATNDIADVKAWAHRFFQRAIDEKRDAYLGLKDTVI 227
>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
latimeri
Length = 158
Score = 52.8 bits (121), Expect = 9e-06
Identities = 24/32 (75%), Positives = 26/32 (81%)
Frame = +1
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
TDESI SFA +S A +KKWPLYLSTKNTIL
Sbjct: 1 TDESIYSFAEASMTTAYEKKWPLYLSTKNTIL 32
>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
Bacteria|Rep: 3-isopropylmalate dehydrogenase -
Symbiobacterium thermophilum
Length = 357
Score = 51.2 bits (117), Expect = 3e-05
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
Frame = +1
Query: 145 VVEMDGDEMTRIIWAKIKERLIFPYV---KVDCLYFDLGLPHRDATDDQVTIDSAHAILK 315
+V ++GD+ + + + RL+ P V + + +DL L +R AT ++V ++A A+ +
Sbjct: 7 IVVLEGDQTGQELLEEAV-RLLSPDVIGLPLHLVRYDLSLENRRATSNRVVYEAAAAMRE 65
Query: 316 HNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTK 495
H G+K ATITP E R + SPN +R + GTV + G T
Sbjct: 66 HGYGLKAATITP-EGRGDVG-------SPNAILRREIDGTVILRTGRPLPGVETIGGITA 117
Query: 496 PIVIGRHAHGDQYKAQDF 549
PI + R A D Y+A+++
Sbjct: 118 PIAVVRMATEDAYEAKEW 135
>UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza
sativa|Rep: Isocitrate dehydrogenase - Oryza sativa
(Rice)
Length = 61
Score = 42.7 bits (96), Expect = 0.009
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +1
Query: 157 DGDEMTRIIWAKIKERLIFPYVKVD 231
DGDEMTRI W IK++LIFP++ +D
Sbjct: 35 DGDEMTRIFWQSIKDKLIFPFLDLD 59
>UniRef50_Q09277 Cluster: Putative uncharacterized protein F40H6.5;
n=1; Caenorhabditis elegans|Rep: Putative
uncharacterized protein F40H6.5 - Caenorhabditis elegans
Length = 1288
Score = 34.7 bits (76), Expect = 2.5
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Frame = +1
Query: 7 HEQW*IHEQYRNMANTSTTKILKCVNQFASLTRNYGTA-KRVVAAKPVVEM-DGDEMTRI 180
++QW I N NT+ + KC++ F +NYG KR+V ++E+ D +T
Sbjct: 730 YQQWTIDTVQMNYQNTNLKYLPKCISIF---QKNYGDLNKRMVNFARIMEVGDNITITGH 786
Query: 181 IWAKIKERLIFPYVKVDCLY 240
IW E YV +D Y
Sbjct: 787 IWQNASESTFNLYVGMDPKY 806
>UniRef50_A0KSD7 Cluster: Putative uncharacterized protein; n=2;
Proteobacteria|Rep: Putative uncharacterized protein -
Shewanella sp. (strain ANA-3)
Length = 112
Score = 33.9 bits (74), Expect = 4.4
Identities = 15/52 (28%), Positives = 27/52 (51%)
Frame = +1
Query: 343 ITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKP 498
+T ++ VEE +++MW+ G I NI G + +P + I + W +P
Sbjct: 53 VTENDAGVEEVNVERMWVIVKGRIDNIYRGQLDNDPYCTEEIRSGMEVWFQP 104
>UniRef50_Q0HEG1 Cluster: Conserved hypothetical biogenesis protein
MshI precursor; n=6; Shewanella|Rep: Conserved
hypothetical biogenesis protein MshI precursor -
Shewanella sp. (strain MR-4)
Length = 292
Score = 33.1 bits (72), Expect = 7.7
Identities = 25/103 (24%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Frame = +1
Query: 10 EQW*IHEQYRNMANTSTTKILKCVNQFA-SLTRNYGTAKRVVAAKPVVEMDGDEMTRIIW 186
EQW +E +N + ++ A + + G + +VA KP V D DE+++ +
Sbjct: 42 EQWVSYELQQNQWQQAFAELANAFPHAALQIVLSSGRYQLLVADKPNV--DSDELSQALL 99
Query: 187 AKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILK 315
IK+ + P ++ YF+ LP V D A+++
Sbjct: 100 WSIKDMVTIPVPQIHLDYFESPLPSNKLNVAVVDKDKLRAMVQ 142
>UniRef50_O17998 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 312
Score = 33.1 bits (72), Expect = 7.7
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Frame = +1
Query: 151 EMDGDEMTRII-WAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVG 327
EMD D +T++ W +IK LI ++ L L LP T +TI + + KH +G
Sbjct: 170 EMDCDGLTKLPHWKRIKSLLIEGFIVSAPLEHFLHLPEVTITMQSITIFNLKLLKKHFLG 229
Query: 328 IK 333
+K
Sbjct: 230 LK 231
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 794,458,547
Number of Sequences: 1657284
Number of extensions: 16319399
Number of successful extensions: 39479
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 38252
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39467
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62969581935
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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