Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brS-0332
(759 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 335 9e-92
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 335 9e-92
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 335 9e-92
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 335 9e-92
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 320 3e-87
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 320 3e-87
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 320 3e-87
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 320 3e-87
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 320 3e-87
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 320 3e-87
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 320 3e-87
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 318 2e-86
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 316 6e-86
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 287 4e-77
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 278 1e-74
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 172 1e-42
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 35 0.28
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 335 bits (824), Expect = 9e-92
Identities = 155/220 (70%), Positives = 179/220 (81%), Gaps = 1/220 (0%)
Frame = +1
Query: 103 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 282
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 283 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 462
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 463 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 639
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 640 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 335 bits (824), Expect = 9e-92
Identities = 155/220 (70%), Positives = 179/220 (81%), Gaps = 1/220 (0%)
Frame = +1
Query: 103 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 282
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 283 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 462
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 463 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 639
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 640 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 335 bits (824), Expect = 9e-92
Identities = 155/220 (70%), Positives = 179/220 (81%), Gaps = 1/220 (0%)
Frame = +1
Query: 103 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 282
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 283 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 462
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 463 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 639
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 640 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 335 bits (824), Expect = 9e-92
Identities = 155/220 (70%), Positives = 179/220 (81%), Gaps = 1/220 (0%)
Frame = +1
Query: 103 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 282
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 283 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 462
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 463 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 639
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 640 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 320 bits (786), Expect = 3e-87
Identities = 149/212 (70%), Positives = 178/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 318 bits (780), Expect = 2e-86
Identities = 149/212 (70%), Positives = 173/212 (81%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDFKT--PGVAMGMYN 663
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + L GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 316 bits (776), Expect = 6e-86
Identities = 147/212 (69%), Positives = 177/212 (83%), Gaps = 2/212 (0%)
Frame = +1
Query: 130 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 309
++ VVEM GDEMTRIIW IKE+LI PYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 310 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 489
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 490 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 663
+PI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 664 TDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 185 QDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 287 bits (703), Expect = 4e-77
Identities = 133/187 (71%), Positives = 159/187 (85%), Gaps = 2/187 (1%)
Frame = +1
Query: 205 LIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLK 384
LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+KCATITPDE+RVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 385 KMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKP 564
+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP P
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 565 GKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYL 738
GKVE+ YT DGT + ++++F+ GVAMGMYN D+SI FAHSSFQ+AL K WPLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 739 STKNTIL 759
STKNTIL
Sbjct: 181 STKNTIL 187
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 278 bits (682), Expect = 1e-74
Identities = 128/179 (71%), Positives = 147/179 (82%), Gaps = 1/179 (0%)
Frame = +1
Query: 226 VDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPN 405
V YFDLGLP+RD TDDQVTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPN
Sbjct: 44 VQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPN 103
Query: 406 GTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVY 585
GTIRNI GGTVFREPI+C++IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+
Sbjct: 104 GTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 163
Query: 586 TTQDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
T +DG+ + +Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTIL
Sbjct: 164 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 222
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 172 bits (418), Expect = 1e-42
Identities = 80/117 (68%), Positives = 96/117 (82%), Gaps = 2/117 (1%)
Frame = +1
Query: 415 RNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQ 594
RNILGGTVF E I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 595 DGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTIL 759
DGT + ++++F+ GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTIL
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 117
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 35.1 bits (77), Expect = 0.28
Identities = 15/43 (34%), Positives = 21/43 (48%)
Frame = +1
Query: 469 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQD 597
PR GW +P + H H DQ +P PGK +L+ +D
Sbjct: 20 PRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLLEQARD 62
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,055,583
Number of Sequences: 237096
Number of extensions: 2558687
Number of successful extensions: 5048
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4871
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5032
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9183116696
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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