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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brS-0304
         (678 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB....   300   2e-80
UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogast...   298   9e-80
UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-...   226   4e-58
UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute car...   217   3e-55
UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-...   208   1e-52
UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exch...   204   2e-51
UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exch...   201   1e-50
UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella ve...   198   1e-49
UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 pr...   196   4e-49
UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:1...   188   1e-46
UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exch...   180   3e-44
UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute car...   178   1e-43
UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-...   173   2e-42
UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchang...   173   3e-42
UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome sh...   172   6e-42
UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/pot...   169   5e-41
UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 pr...   168   9e-41
UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exch...   167   3e-40
UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium excha...   165   7e-40
UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella ve...   163   3e-39
UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx...   163   4e-39
UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exch...   162   6e-39
UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; ...   161   2e-38
UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 pr...   160   3e-38
UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exch...   159   4e-38
UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve...   159   8e-38
UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchang...   156   5e-37
UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 pr...   156   5e-37
UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potass...   154   2e-36
UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:...   153   5e-36
UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - M...   151   2e-35
UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome s...   150   4e-35
UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleosto...   149   5e-35
UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus nor...   149   5e-35
UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (N...   149   5e-35
UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchang...   149   8e-35
UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N...   148   1e-34
UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Eut...   147   2e-34
UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|...   147   2e-34
UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella ve...   143   3e-33
UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;...   142   7e-33
UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella ve...   136   5e-31
UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amure...   135   1e-30
UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchang...   133   3e-30
UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calci...   128   1e-28
UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchang...   124   2e-27
UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n...   124   2e-27
UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogas...   122   6e-27
UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isof...   116   4e-25
UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodiu...   113   4e-24
UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gamb...   113   5e-24
UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc...   100   4e-20
UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaste...    98   2e-19
UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061...    97   3e-19
UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis ...    82   1e-14
UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/cal...    65   1e-09
UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger...    64   2e-09
UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependen...    62   2e-08
UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-...    58   1e-07
UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus ...    55   1e-06
UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, who...    54   4e-06
UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antip...    51   2e-05
UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; ...    50   5e-05
UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus...    48   3e-04
UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole gen...    48   3e-04
UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenor...    48   3e-04
UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr...    47   4e-04
UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-...    47   4e-04
UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella ve...    47   5e-04
UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    46   6e-04
UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related ...    46   6e-04
UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis th...    46   6e-04
UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; A...    46   8e-04
UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|...    46   8e-04
UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep...    46   0.001
UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-...    46   0.001
UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-...    45   0.001
UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneum...    45   0.002
UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobac...    45   0.002
UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-...    44   0.003
UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;...    44   0.003
UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: ...    44   0.005
UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-...    44   0.005
UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane regio...    43   0.008
UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 pre...    43   0.008
UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; T...    42   0.010
UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; ...    42   0.010
UniRef50_UPI00006CE59A Cluster: probable Mg2+-specific channel-l...    42   0.014
UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    42   0.014
UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-...    42   0.014
UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Ar...    42   0.014
UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; H...    42   0.014
UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    42   0.018
UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; R...    42   0.018
UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091...    42   0.018
UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; ...    41   0.024
UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    41   0.024
UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; ...    41   0.024
UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:...    41   0.024
UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteob...    41   0.032
UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    41   0.032
UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger prote...    40   0.042
UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; ...    40   0.042
UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteob...    40   0.056
UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    40   0.056
UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; F...    40   0.056
UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;...    40   0.056
UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomon...    40   0.056
UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriacea...    40   0.056
UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; ...    40   0.056
UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;...    40   0.074
UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; ...    40   0.074
UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein...    40   0.074
UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    40   0.074
UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na...    40   0.074
UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloa...    40   0.074
UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamm...    39   0.097
UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillat...    39   0.097
UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Re...    39   0.097
UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-...    39   0.13 
UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like pro...    39   0.13 
UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisph...    39   0.13 
UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    39   0.13 
UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|...    39   0.13 
UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; M...    39   0.13 
UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protei...    38   0.17 
UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; ...    38   0.17 
UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:...    38   0.17 
UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (N...    38   0.17 
UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca exch...    38   0.22 
UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.22 
UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.22 
UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.22 
UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; ...    38   0.22 
UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; ...    38   0.22 
UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; ...    38   0.22 
UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-...    38   0.30 
UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; C...    38   0.30 
UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-...    37   0.39 
UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P...    37   0.39 
UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-...    37   0.39 
UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger prote...    37   0.39 
UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like p...    37   0.39 
UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halob...    37   0.39 
UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria...    37   0.52 
UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriph...    37   0.52 
UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 pr...    37   0.52 
UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/pot...    36   0.69 
UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; ...    36   0.69 
UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:...    36   0.69 
UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precu...    36   0.91 
UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    36   0.91 
UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-...    36   0.91 
UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    36   0.91 
UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole geno...    36   0.91 
UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family tr...    36   1.2  
UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;...    36   1.2  
UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein...    36   1.2  
UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorha...    36   1.2  
UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; ...    36   1.2  
UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31; Coeloma...    35   1.6  
UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomon...    35   1.6  
UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    35   1.6  
UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella ve...    35   1.6  
UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum sy...    35   1.6  
UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH04...    35   2.1  
UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-...    35   2.1  
UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antip...    35   2.1  
UniRef50_A2Q2A6 Cluster: Zinc finger, RING-type; Transcription f...    35   2.1  
UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Ente...    35   2.1  
UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whol...    34   2.8  
UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; ...    34   2.8  
UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whol...    34   3.7  
UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacte...    34   3.7  
UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; A...    34   3.7  
UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3; Tetrah...    34   3.7  
UniRef50_Q6CTM9 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    34   3.7  
UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; ...    34   3.7  
UniRef50_P13983 Cluster: Extensin precursor; n=1; Nicotiana taba...    34   3.7  
UniRef50_UPI00006CC43D Cluster: Major Facilitator Superfamily pr...    33   4.8  
UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precu...    33   4.8  
UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whol...    33   4.8  
UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-...    33   4.8  
UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;...    33   4.8  
UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; ...    33   4.8  
UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-...    33   4.8  
UniRef50_Q5ZC54 Cluster: Putative uncharacterized protein P0443D...    33   4.8  
UniRef50_A2WKF8 Cluster: Putative uncharacterized protein; n=2; ...    33   4.8  
UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, wh...    33   4.8  
UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome s...    33   6.4  
UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    33   6.4  
UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, e...    33   6.4  
UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (N...    33   6.4  
UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; ...    33   8.4  
UniRef50_Q1ARL7 Cluster: Sodium/calcium exchanger membrane regio...    33   8.4  
UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; A...    33   8.4  
UniRef50_Q8ILY2 Cluster: Putative uncharacterized protein; n=1; ...    33   8.4  
UniRef50_A0BCS6 Cluster: Chromosome undetermined scaffold_10, wh...    33   8.4  

>UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.3;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG2893-PB.3 - Tribolium castaneum
          Length = 480

 Score =  300 bits (736), Expect = 2e-80
 Identities = 141/189 (74%), Positives = 156/189 (82%), Gaps = 4/189 (2%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCTPPAIDDFP   FTE +RQ GA+V+H ++S+YLF+ALAVVCDK+FVPAVEKICHALNM
Sbjct: 4   NCTPPAIDDFPRDFFTEKERQDGAVVVHVVVSLYLFVALAVVCDKFFVPAVEKICHALNM 63

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM- 442
           + DV            PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG+ 
Sbjct: 64  SADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGLC 123

Query: 443 ---VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613
              VVPLDWWPLTRDCLAYGITVSILICIIHDE V+WYEA  LV LY VYI IMY+DK I
Sbjct: 124 GVKVVPLDWWPLTRDCLAYGITVSILICIIHDERVEWYEALTLVLLYTVYILIMYFDKSI 183

Query: 614 QNFAKGSWE 640
           Q  A+G ++
Sbjct: 184 QRCARGGFK 192


>UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila
           melanogaster|Rep: CG2893-PC.3 - Drosophila melanogaster
           (Fruit fly)
          Length = 542

 Score =  298 bits (731), Expect = 9e-80
 Identities = 134/182 (73%), Positives = 152/182 (83%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCT PAIDDFP  LF+E QRQ GA+VLH + S+YLF+ALAVVCD+YFVPAVEKIC ALNM
Sbjct: 21  NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNM 80

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
           +NDV            PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 
Sbjct: 81  SNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMT 140

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625
           +PLDWWPLTRD +AYG+TV+ILIC++HDE V+WYEA +LVSLY VY+ +MY+DK  Q  A
Sbjct: 141 IPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCA 200

Query: 626 KG 631
           KG
Sbjct: 201 KG 202


>UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative -
           Nasonia vitripennis
          Length = 561

 Score =  226 bits (552), Expect = 4e-58
 Identities = 98/176 (55%), Positives = 127/176 (72%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCTPP+I +FP+   T  QRQHG IV+H +I+ Y F  LA+VCD +FVP++ KIC  + M
Sbjct: 95  NCTPPSIKEFPSDGLTRYQRQHGFIVIHVIIACYAFFLLAIVCDDFFVPSIVKICDKIGM 154

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
           + DV            PELF+N++GTF+TEGD+GVGTIVGSAVFNILAV ACCG+ A  V
Sbjct: 155 SKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNILAVPACCGLFASQV 214

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613
           + LDWWP++RD LAYG+TV +LI  +HD  ++WYEAF+LV  Y  YI  M ++K I
Sbjct: 215 LDLDWWPISRDSLAYGVTVLLLIFTLHDGRIEWYEAFILVLFYIFYILAMVFNKRI 270


>UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute
           carrier family 24, member 5; n=1; Apis mellifera|Rep:
           PREDICTED: similar to solute carrier family 24, member 5
           - Apis mellifera
          Length = 439

 Score =  217 bits (529), Expect = 3e-55
 Identities = 96/179 (53%), Positives = 130/179 (72%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCTPPAI +FP+   T  QRQ G I++H +I+IY+FL LA+VCD +FVP+++KIC  +N+
Sbjct: 23  NCTPPAIKEFPSDGLTREQRQLGFILIHFVIAIYMFLLLAIVCDDFFVPSIKKICDKINV 82

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
           + DV            PELF+N++GTFITEGD+GVGTIVGSAVFNILAV ACCG+ A  +
Sbjct: 83  SEDVAGATIMATATSSPELFINIVGTFITEGDLGVGTIVGSAVFNILAVPACCGLFANQI 142

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
           + L+ WP+TRD +AY ITV +LI  + D  ++WYEA +LV  Y +YI +M +D+ I  F
Sbjct: 143 LNLEAWPVTRDTIAYAITVFLLILTLRDGRIEWYEALILVLSYFLYILVMCFDRNIHQF 201


>UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to
           potassium-dependent Na/Ca exchanger NCKX3; n=2;
           Deuterostomia|Rep: PREDICTED: similar to
           potassium-dependent Na/Ca exchanger NCKX3 -
           Strongylocentrotus purpuratus
          Length = 570

 Score =  208 bits (507), Expect = 1e-52
 Identities = 91/173 (52%), Positives = 119/173 (68%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCTP  I++FP  LFTE QR  GA + HA+ ++Y+F+ALA+VCD YFV ++EKIC  L++
Sbjct: 75  NCTPSTIEEFPGDLFTEEQRAKGAFITHAICAVYMFIALAIVCDDYFVSSLEKICENLSL 134

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
           T DV            PELF +VIG FI +GD+GVGTIVGSAVFNIL +   CG+ AG V
Sbjct: 135 TEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGLCGLFAGQV 194

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604
           V L WWPL RD L Y I+V  L+ +I D Y+ WYEA +++ +Y  Y+ IM +D
Sbjct: 195 VHLSWWPLFRDTLVYAISVVTLVLVIRDGYINWYEALVMLLMYLCYVIIMCFD 247


>UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=1; Aedes aegypti|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 492

 Score =  204 bits (497), Expect = 2e-51
 Identities = 95/122 (77%), Positives = 101/122 (82%)
 Frame = +2

Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           M+NDV            PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM
Sbjct: 1   MSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60

Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
           VVPLDWWPLTRDCLAYGITV+ILICIIHDE V+WYEA +LV LY VYI +MYYDK  Q  
Sbjct: 61  VVPLDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYIAVMYYDKAFQKC 120

Query: 623 AK 628
           A+
Sbjct: 121 AR 122


>UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=3; Endopterygota|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 542

 Score =  201 bits (491), Expect = 1e-50
 Identities = 94/180 (52%), Positives = 119/180 (66%)
 Frame = +2

Query: 83  RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262
           RNCTP AI +FP+  FT  +R+HG I +H LI+ Y F  LA+VCD YFVPA+E +C  L 
Sbjct: 95  RNCTPAAIFEFPSDGFTREERKHGWITVHLLIACYCFWLLAIVCDDYFVPAIELMCKKLQ 154

Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           +  D+            PELF+N +GTFIT+GDIGVG +VGSAVFNILAV A CG+  G 
Sbjct: 155 VKEDIAGATFMAAASSSPELFINCVGTFITKGDIGVGAVVGSAVFNILAVPAVCGLFGGQ 214

Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
           VV L WWP+TRD + YG+ V  LI +++D  V WYEA +LVS Y +YI  M  +  I  F
Sbjct: 215 VVQLRWWPVTRDSMMYGMAVIGLITVLNDGKVMWYEATILVSAYVLYITAMICNDSINRF 274


>UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 490

 Score =  198 bits (482), Expect = 1e-49
 Identities = 91/179 (50%), Positives = 121/179 (67%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCTPPAI +FP   FT+ QRQ GA+VL+ +IS+Y+F A+A+VCD YFVP +E IC  L +
Sbjct: 1   NCTPPAILEFPDDFFTQRQRQRGAVVLNFIISLYMFWAVAIVCDDYFVPCLEIICDRLGL 60

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
             DV            PELF +VIG FIT+GDIGVGTI+GSAVFN+L V   CG+GAG V
Sbjct: 61  QTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTV 120

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
           + L WWP+ RD + Y  ++  L+ ++ D  V W EA  +VS Y VY+ IMY++  I+ +
Sbjct: 121 LYLAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLLIMYFNPRIEAY 179


>UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3); n=55;
           Eumetazoa|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) - Homo
           sapiens (Human)
          Length = 644

 Score =  196 bits (478), Expect = 4e-49
 Identities = 90/174 (51%), Positives = 120/174 (68%)
 Frame = +2

Query: 83  RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262
           +NCT PA+ +FP  +FT   R+ GA+VLH L +IY+F ALA+VCD +FVP++EKIC  L+
Sbjct: 85  KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144

Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           ++ DV            PELF +VIG FIT+GD+GVGTIVGSAVFNIL +   CG+ AG 
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204

Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604
           VV L  W L RD + Y ++V  LI  I+DE V W+E+ +LV +Y +YI IM Y+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYN 258


>UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep:
           Zgc:112072 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 569

 Score =  188 bits (457), Expect = 1e-46
 Identities = 88/183 (48%), Positives = 120/183 (65%)
 Frame = +2

Query: 83  RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262
           +NCT PAI +FP  LFT  QR  GA++LH   ++Y+FLALA+VCD YFV ++EKIC  L+
Sbjct: 59  KNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDDYFVTSLEKICEKLH 118

Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           ++ DV            PELF ++IG FIT GD+GVGTIVGSAVFNIL +   CGI AG 
Sbjct: 119 LSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQ 178

Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
           VV L  + + RD   Y I+V  LI  I+D+ + W+E+ +L+ +Y  YI +M ++  +QN 
Sbjct: 179 VVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLGYIIVMKFNTSLQNL 238

Query: 623 AKG 631
             G
Sbjct: 239 FNG 241


>UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca
           exchanger 5; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Na-Ca exchanger 5 - Apis mellifera
          Length = 489

 Score =  180 bits (438), Expect = 3e-44
 Identities = 82/178 (46%), Positives = 115/178 (64%)
 Frame = +2

Query: 83  RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262
           + CT  +I DFP  LFT  QR+HGA++LHA + +Y FL  A VC  Y +PAV++IC +LN
Sbjct: 24  KKCTDRSIHDFPEDLFTYEQRRHGAVILHAFLGLYCFLLTAFVCHDYLLPAVDRICISLN 83

Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           ++ DV            PELFVNVIGTF+TE D+G GT+VGSAVF+  A  AC  +    
Sbjct: 84  ISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFDTFATPACGALMTFY 143

Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 616
            + L+W  L+RDCL Y I+V  L+ I+ D  +QWYEA +L+ L+  Y+ +++  K I+
Sbjct: 144 AISLEWQVLSRDCLMYVISVGTLVIIMWDAKIQWYEAMILLILFCFYLILLFCGKHIR 201


>UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute
           carrier family 24, member 5; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to solute carrier
           family 24, member 5 - Tribolium castaneum
          Length = 488

 Score =  178 bits (433), Expect = 1e-43
 Identities = 80/172 (46%), Positives = 113/172 (65%)
 Frame = +2

Query: 107 DDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXX 286
           +DFP+ +FTE Q + G I+L   I IY F  LA++CD YF+P VEKIC ALN+++DV   
Sbjct: 50  EDFPS-MFTETQVEKGGIILVFCIGIYCFTLLAIICDNYFLPCVEKICEALNLSHDVAAA 108

Query: 287 XXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP 466
                    PELFVN+IGTFITE DIG+GT+VGS++FN L VA+   + A   V L WWP
Sbjct: 109 TFMSVATSTPELFVNIIGTFITESDIGIGTVVGSSLFNTLGVASLGSLAASTPVQLHWWP 168

Query: 467 LTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
           ++RD + Y +++ +L+ I  D Y+ WYE  +L  +Y +Y  +M+ +  I NF
Sbjct: 169 ISRDVIIYILSILLLVGITWDGYIYWYEGLVLFLVYFIYFTVMFQNVRISNF 220


>UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative -
           Nasonia vitripennis
          Length = 692

 Score =  173 bits (422), Expect = 2e-42
 Identities = 79/198 (39%), Positives = 120/198 (60%)
 Frame = +2

Query: 35  TTPLQNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVC 214
           TTP  + + + R     NC+PPAI+ FP  L     R+HG +V+H L++IY FL LA+VC
Sbjct: 139 TTPFIDTHPTWRPRR-ENCSPPAIEQFPRPLMGPYARKHGGLVIHVLVAIYTFLGLAIVC 197

Query: 215 DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAV 394
           D YFV ++++IC  L ++ DV            PEL   VIG F  + DIGV  ++GSAV
Sbjct: 198 DDYFVASLDRICEELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAV 257

Query: 395 FNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLY 574
           FNI+ V + CG+ +  V  L+WWPL RDC  Y I++ +++  I +E + W EA  ++ +Y
Sbjct: 258 FNIMFVISVCGLCSSTVSKLNWWPLCRDCFFYFISILVMLGTIANESISWGEALFMLIMY 317

Query: 575 GVYICIMYYDKPIQNFAK 628
           GVY   + ++  ++ +AK
Sbjct: 318 GVYCVALAFNSTLERWAK 335


>UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchanger
           5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5).; n=1; Takifugu
           rubripes|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5). - Takifugu rubripes
          Length = 473

 Score =  173 bits (421), Expect = 3e-42
 Identities = 79/179 (44%), Positives = 113/179 (63%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           +C PP   +FP G FT  +R+ G +V++ LI  Y+ LA+++VCD YF+P++E I   L +
Sbjct: 1   DCVPPQSSEFPDGFFTVQERKDGGLVIYFLIIFYMLLAVSIVCDDYFLPSLEVISERLGL 60

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
           + DV            PEL    +G F+T+GDIGV TIVGSAV+N+L + A CG+   + 
Sbjct: 61  SQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGLLTTVA 120

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
             L  WPL RDCLAYGI+V+ +I II+D  V WY+A  L+ +Y VYI ++ +D  I  F
Sbjct: 121 GRLTCWPLFRDCLAYGISVTAVIAIIYDNKVYWYDAASLLLVYMVYIVVLCFDLRISEF 179


>UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF15008, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 557

 Score =  172 bits (419), Expect = 6e-42
 Identities = 75/150 (50%), Positives = 105/150 (70%)
 Frame = +2

Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG 358
           +IY+FLALAVVCD YFVP++EK+   L+++ DV            PELF ++IG FITEG
Sbjct: 1   AIYMFLALAVVCDVYFVPSLEKLSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEG 60

Query: 359 DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYV 538
           D+GVGTIVGSAVFNIL +   CGI AG  + L WWPL RD + Y +++ +LI +I+DE V
Sbjct: 61  DVGVGTIVGSAVFNILVIIGICGIFAGQPISLSWWPLFRDAVFYILSILVLILVIYDEKV 120

Query: 539 QWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            W+E  +L+S+YG+YI IM +++ +    +
Sbjct: 121 MWWETIILISMYGIYIIIMKFNRSLHGLVE 150


>UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to
           Sodium/potassium/calcium exchanger
           (Na(+)/K(+)/Ca(2+)-exchange protein); n=2;
           Endopterygota|Rep: PREDICTED: similar to
           Sodium/potassium/calcium exchanger
           (Na(+)/K(+)/Ca(2+)-exchange protein) - Apis mellifera
          Length = 658

 Score =  169 bits (411), Expect = 5e-41
 Identities = 76/181 (41%), Positives = 109/181 (60%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           N T      FP  LFT  QR+ GA++LH +  +Y+F+ALA+VCD++FVP+++ I   L +
Sbjct: 103 NMTEEKAPLFPQDLFTVHQRRRGAVILHVIGVVYMFVALAIVCDEFFVPSLDVIIEKLEI 162

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
            +DV            PELF ++IG F++  D+G+GTIVGSAVFNIL V   C I +  V
Sbjct: 163 ADDVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAIFSRTV 222

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625
           + L WWPL RDC  Y  ++  LI    D Y+ WYEA +L   Y  Y+  M +++P++   
Sbjct: 223 LSLTWWPLFRDCTFYSASLLTLIYFFRDNYIHWYEALVLFGFYLAYVSFMKWNQPMEKLV 282

Query: 626 K 628
           K
Sbjct: 283 K 283


>UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=20;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Homo
           sapiens (Human)
          Length = 500

 Score =  168 bits (409), Expect = 9e-41
 Identities = 72/183 (39%), Positives = 114/183 (62%)
 Frame = +2

Query: 74  GYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICH 253
           G    C      +FP G FT  +R+ G I+++ LI +Y+F+A+++VCD+YF+P++E I  
Sbjct: 41  GNSTQCVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISE 100

Query: 254 ALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIG 433
           +L ++ DV            PEL    +G FIT+GDIG+ TI+GSA++N+L + A CG+ 
Sbjct: 101 SLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLL 160

Query: 434 AGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613
           +  V  L  WPL RDC AY I+ + ++ II+D  V WYE  LL+ +YG+Y+ ++ +D  I
Sbjct: 161 SNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKI 220

Query: 614 QNF 622
             +
Sbjct: 221 NQY 223


>UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=2; Culicidae|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 549

 Score =  167 bits (405), Expect = 3e-40
 Identities = 75/176 (42%), Positives = 104/176 (59%)
 Frame = +2

Query: 101 AIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVX 280
           AID+ P  +FT+ QR  GAI+LH + +IY F  LA +  +YF+P+VE IC  L +T DV 
Sbjct: 87  AIDELPDDVFTQEQRLQGAIILHFIGAIYFFTLLAYIVGEYFLPSVECICEDLKLTQDVA 146

Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW 460
                      PE F N I TFI + D+G+GTI+GS +FN L VA   G+     V LDW
Sbjct: 147 AATFMAIAGTIPEFFTNTISTFIADSDMGIGTIMGSLLFNTLGVACLAGLACKKPVQLDW 206

Query: 461 WPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
           WP+TRDC+ +   +S+L+    D  + WYE+ + V L   Y  +M+ +KPI   AK
Sbjct: 207 WPITRDCIVFAFHISVLVGFAWDGRIYWYESMVFVILLFTYFVVMFQNKPIMKLAK 262


>UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium
           exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein
           CG1090); n=5; Bilateria|Rep: Probable
           sodium/potassium/calcium exchanger CG1090
           (Na(+)/K(+)/Ca(2+)- exchange protein CG1090) -
           Drosophila melanogaster (Fruit fly)
          Length = 642

 Score =  165 bits (402), Expect = 7e-40
 Identities = 67/182 (36%), Positives = 114/182 (62%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265
           NCTPPAI+ FP  L  +  RQHG ++LH L++++ F  LA+VCD+YFV +++++C  L +
Sbjct: 101 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKL 160

Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445
           + DV            PEL   VIG F  + DIG+  ++GSAVFNI+ V + C + +G V
Sbjct: 161 SPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTV 220

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625
             L+WWPL RDC  Y +++ +++ II ++ +  +E+ +++  Y  Y   ++++  ++ +A
Sbjct: 221 CQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGYCVALHFNTELERWA 280

Query: 626 KG 631
            G
Sbjct: 281 LG 282


>UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 429

 Score =  163 bits (397), Expect = 3e-39
 Identities = 72/180 (40%), Positives = 110/180 (61%)
 Frame = +2

Query: 89  CTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMT 268
           C PP I++FP  + T+ QR +G ++LH + S++LF AL VVC+ +FV ++ +I   L + 
Sbjct: 1   CRPPNIEEFPPDVLTQDQRFYGGVMLHVIFSLHLFCALTVVCEDFFVASLNRISMCLGLK 60

Query: 269 NDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
            DV            P LF+ +I  F TEGDIG+GTIVGS +FN L + A C IG+G+ +
Sbjct: 61  PDVAGATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTL 120

Query: 449 PLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            L  +P++RD   Y  +V +L+  I+D  V WYE  + V +Y +YI IMY++  ++   K
Sbjct: 121 QLACYPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMYFNDQVEGLCK 180


>UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx30C
           (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C); n=7;
           Diptera|Rep: Sodium/potassium/calcium exchanger Nckx30C
           (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) -
           Drosophila melanogaster (Fruit fly)
          Length = 888

 Score =  163 bits (396), Expect = 4e-39
 Identities = 76/186 (40%), Positives = 114/186 (61%)
 Frame = +2

Query: 71  DGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKIC 250
           D +  N T      FP  LFT+ Q ++GA++LH +  IY+F+ALA+VCD++FVP+++ I 
Sbjct: 304 DTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVII 363

Query: 251 HALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
             L +T+DV            PELF +VIG F++  D+G+GTIVGSAVFNIL V   C +
Sbjct: 364 EKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAL 423

Query: 431 GAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKP 610
            +  V+ L WWPL RDC  Y I++ +LI    D  + W+EA +L ++Y  Y+  M ++  
Sbjct: 424 FSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQ 483

Query: 611 IQNFAK 628
           ++   K
Sbjct: 484 VETCVK 489


>UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium
           exchanger; n=5; Coelomata|Rep: Potassium-dependent
           sodium-calcium exchanger - Aedes aegypti (Yellowfever
           mosquito)
          Length = 207

 Score =  162 bits (394), Expect = 6e-39
 Identities = 74/173 (42%), Positives = 109/173 (63%)
 Frame = +2

Query: 113 FPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXX 292
           FP  LFT  QR++GA+VLH L  IY+F+ALA+VCD++FVP+++ I   L +T+DV     
Sbjct: 1   FPEDLFTLEQRRNGAVVLHILGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATF 60

Query: 293 XXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT 472
                  PELF +VIG F++  D+G+GTIVGSAVFNIL V   C + +  ++ L WWPL 
Sbjct: 61  MAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTLLTLTWWPLF 120

Query: 473 RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 631
           RDC  Y +++  LI    D  ++W+EA +L  +Y  Y   M +++ ++    G
Sbjct: 121 RDCTFYSVSLLTLIYFFRDNSIEWWEALVLFIIYIAYAVFMKFNQTVERCCGG 173


>UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           RE34149p - Nasonia vitripennis
          Length = 542

 Score =  161 bits (390), Expect = 2e-38
 Identities = 77/193 (39%), Positives = 110/193 (56%)
 Frame = +2

Query: 35  TTPLQNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVC 214
           T P  N + S     + NC   +I+DFP  LFT  QRQ GAI+ H    +Y FL  A VC
Sbjct: 39  TKPPTNASESTNPA-VENCLAHSIEDFPEDLFTLQQRQQGAILFHIFFGLYCFLLTAFVC 97

Query: 215 DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAV 394
           + Y +PA++ IC  L ++ DV            PELFVNV+GTF+TE D+GVG +VG AV
Sbjct: 98  NDYLLPALDCICADLRISADVAGATFLATASCFPELFVNVVGTFLTESDLGVGAVVGGAV 157

Query: 395 FNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLY 574
           FN  A  A   + A   + L W  L+RDC+ Y  +V +L+ ++ D  V WYE+ +L+ L+
Sbjct: 158 FNTFATPAVGALFAAKGIQLQWHILSRDCVIYSFSVGVLVLVMWDGLVTWYESVILLFLF 217

Query: 575 GVYICIMYYDKPI 613
             Y  +++ +  I
Sbjct: 218 ASYFTLLFVNDSI 230


>UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=7;
           Murinae|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Mus
           musculus (Mouse)
          Length = 501

 Score =  160 bits (388), Expect = 3e-38
 Identities = 70/180 (38%), Positives = 108/180 (60%)
 Frame = +2

Query: 74  GYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICH 253
           G    C      +FP G FT+ +   G IV++ LI +Y+ +A+++VCDKYF+P++E I  
Sbjct: 41  GNSTQCAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISD 100

Query: 254 ALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIG 433
           +L ++ DV            PEL    +G FIT+GDIG+ TI+GSA++N+L + A CG+ 
Sbjct: 101 SLGLSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLL 160

Query: 434 AGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613
           + MV  L  WPL RDC  Y ++V  +  II D  + WYE   L+ +YG+Y+ ++ +D  I
Sbjct: 161 SNMVSTLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTI 220


>UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=1; Aedes aegypti|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 520

 Score =  159 bits (387), Expect = 4e-38
 Identities = 74/175 (42%), Positives = 107/175 (61%)
 Frame = +2

Query: 101 AIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVX 280
           ++DD P  LF++ +R +GAI+LH L +IY F  LA VC +YF+P+VE IC  L+++ DV 
Sbjct: 66  SMDDLPPDLFSKTERLNGAIILHFLAAIYFFTILAYVCSEYFLPSVEYICEDLHLSEDVA 125

Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW 460
                      PE F N I T + + D+G+GTI+GS +FN L VAA  G+     V LDW
Sbjct: 126 AATFMATATSMPEFFTNTISTLVVDSDMGLGTIMGSMLFNTLGVAALVGLLTKSHVKLDW 185

Query: 461 WPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625
           WPLTRD +   I+ S L+  + DE V WYE+ + V LY +Y  +M+ +  ++  A
Sbjct: 186 WPLTRDSIIVIISTSSLVSCLWDERVYWYESLVFVVLYVLYFLVMFQNDRMKRIA 240


>UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 639

 Score =  159 bits (385), Expect = 8e-38
 Identities = 68/172 (39%), Positives = 108/172 (62%)
 Frame = +2

Query: 125 LFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXX 304
           +FT  +R+HGA+++H  I +Y F+ALA++CD YF  ++EK+C  L +  DV         
Sbjct: 39  IFTLQERRHGAVIIHTFICLYCFVALAILCDNYFCASLEKLCKRLRIPTDVAGATFMAAG 98

Query: 305 XXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL 484
              P LF+ +   F+ EGDIG+GTI+GS++FNIL + A CG+ +GMV+ L  WP+ RD  
Sbjct: 99  SSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVISLHTWPIVRDSC 158

Query: 485 AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGSWE 640
            Y + +  L+ +IHD  + +YEA +   LY  YI IM ++  ++N  + ++E
Sbjct: 159 VYVVNLVGLLIVIHDNVIHFYEALIFPVLYTGYILIMVFNTRLENAFESAFE 210


>UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchanger
           3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3).; n=1; Danio
           rerio|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3). - Danio rerio
          Length = 419

 Score =  156 bits (378), Expect = 5e-37
 Identities = 74/147 (50%), Positives = 96/147 (65%)
 Frame = +2

Query: 182 IYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD 361
           +Y+F ALA+VCD YFVP++EKIC  L+++ DV            PELF +VIG FIT+GD
Sbjct: 1   MYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGD 60

Query: 362 IGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 541
           +GVGTIVGSAVFNIL +   CGI     V L  W L RD   Y I V+ LI  I+DE V 
Sbjct: 61  VGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVT 120

Query: 542 WYEAFLLVSLYGVYICIMYYDKPIQNF 622
           W+E+ +L+ LY VYI IM ++  + +F
Sbjct: 121 WWESLILIVLYLVYILIMKFNSRVVHF 147


>UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2); n=34;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 2
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) - Homo
           sapiens (Human)
          Length = 661

 Score =  156 bits (378), Expect = 5e-37
 Identities = 71/187 (37%), Positives = 113/187 (60%)
 Frame = +2

Query: 68  RDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKI 247
           ++G   N T  A  D+P  +F+  +R+ GAI+LH +  IY+F+ALA+VCD++FVP++  I
Sbjct: 105 KEGESENSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVI 164

Query: 248 CHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG 427
              L +++DV            PELF ++IG FI   ++G+GTIVGSAVFNIL V   C 
Sbjct: 165 TEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCA 224

Query: 428 IGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607
           + +  ++ L WWPL RD   Y + + +LI    D  + W+E+ LL++ Y  Y+  M ++ 
Sbjct: 225 LFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNV 284

Query: 608 PIQNFAK 628
            ++ + K
Sbjct: 285 QVEKWVK 291


>UniRef50_Q91WD8 Cluster: Solute carrier family 24
           (Sodium/potassium/calcium exchanger), member 1; n=2;
           Eutheria|Rep: Solute carrier family 24
           (Sodium/potassium/calcium exchanger), member 1 - Mus
           musculus (Mouse)
          Length = 1130

 Score =  154 bits (374), Expect = 2e-36
 Identities = 71/173 (41%), Positives = 108/173 (62%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P  LF+   R+ G +VLH    +Y+F+ALA+VCD+YFVPA+  I H L ++ DV    
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGAT 465

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  ++ L WWPL
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            RD   Y + +S+LI    D ++ W+E+ LL+  Y +Y+  M ++K I+ + K
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSFIAWWESLLLLLAYALYVFTMKWNKQIELWVK 578


>UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:
           Slc24a2 protein - Mus musculus (Mouse)
          Length = 711

 Score =  153 bits (370), Expect = 5e-36
 Identities = 69/189 (36%), Positives = 112/189 (59%)
 Frame = +2

Query: 62  SERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVE 241
           + ++    N T     D+P  +F+  +R+ GAI+LH +  IY+F+ALA+VCD++FVP++ 
Sbjct: 104 ASQEDQAENSTEHTQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLT 163

Query: 242 KICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAAC 421
            I   L +++DV            PELF ++IG FI   ++G+GTIVGSAVFNIL V   
Sbjct: 164 VITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 223

Query: 422 CGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601
           C + +  ++ L WWPL RD   Y + + +LI    D  + W+E+ LL++ Y  Y+  M +
Sbjct: 224 CALFSREILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKF 283

Query: 602 DKPIQNFAK 628
           +  ++ + K
Sbjct: 284 NVQVERWVK 292


>UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 -
           Morone saxatilis (Striped bass)
          Length = 749

 Score =  151 bits (366), Expect = 2e-35
 Identities = 73/173 (42%), Positives = 106/173 (61%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           D+P  LF+  QRQ G +VLH +  IY+F+ALA+VCD++FVP +E I + L +++DV    
Sbjct: 140 DYPEDLFSVEQRQQGWVVLHVIGMIYMFVALAIVCDEFFVPGLEVITNKLQISDDVAGAT 199

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C I +  ++ L WWPL
Sbjct: 200 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAIFSREMLHLTWWPL 259

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            RD   Y + + +LI    D  + W+E+ LLV  Y  Y+  M ++  I+   K
Sbjct: 260 FRDVSFYILDLIMLIVFFLDNTILWWESILLVLGYISYVSFMKFNSQIEQAVK 312


>UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome
           shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 13
           SCAF14555, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 647

 Score =  150 bits (363), Expect = 4e-35
 Identities = 72/179 (40%), Positives = 108/179 (60%), Gaps = 1/179 (0%)
 Frame = +2

Query: 95  PPAID-DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTN 271
           PP +  ++P  LF+   R+ G +VLH +  +Y+F+ALA+VCD++FVPA+  I H L +++
Sbjct: 126 PPQVKGEYPEDLFSIKDRRRGWVVLHIIGMMYMFIALAIVCDEFFVPALGVITHKLAISD 185

Query: 272 DVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 451
           DV            PELF ++IG FI   ++G+GTIVGSAVFNIL V   C + +  V+ 
Sbjct: 186 DVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREVLH 245

Query: 452 LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
           L WWPL RD   Y + + +LI    D  + W+E+ +LV  Y VY+  M ++  I+   K
Sbjct: 246 LTWWPLFRDVSFYILDLVMLIVFFLDNVIMWWESMMLVGGYTVYVIFMKFNVQIERAFK 304


>UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3;
           Euteleostomi|Rep: Isoform 4 of Q9QZM6 - Rattus
           norvegicus (Rat)
          Length = 1153

 Score =  149 bits (362), Expect = 5e-35
 Identities = 70/173 (40%), Positives = 105/173 (60%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P  LF+   R+ G +VLH     Y+F+ALA+VCD+YFVPA+  I   L ++ DV    
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  ++ L WWPL
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            RD   Y + +S+LI    D  + W+E+ LL+  Y +Y+  M ++K I+ + K
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVK 578


>UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus
           norvegicus|Rep: Isoform 3 of Q9QZM6 - Rattus norvegicus
           (Rat)
          Length = 1086

 Score =  149 bits (362), Expect = 5e-35
 Identities = 70/173 (40%), Positives = 105/173 (60%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P  LF+   R+ G +VLH     Y+F+ALA+VCD+YFVPA+  I   L ++ DV    
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  ++ L WWPL
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            RD   Y + +S+LI    D  + W+E+ LL+  Y +Y+  M ++K I+ + K
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVK 578


>UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1
           (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=13;
           Fungi/Metazoa group|Rep: Sodium/potassium/calcium
           exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) -
           Rattus norvegicus (Rat)
          Length = 1181

 Score =  149 bits (362), Expect = 5e-35
 Identities = 70/173 (40%), Positives = 105/173 (60%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P  LF+   R+ G +VLH     Y+F+ALA+VCD+YFVPA+  I   L ++ DV    
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  ++ L WWPL
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            RD   Y + +S+LI    D  + W+E+ LL+  Y +Y+  M ++K I+ + K
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVK 578


>UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchanger
           2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2)
           (Retinal cone Na-Ca+K exchanger) (Solute carrier family
           24 member 2).; n=1; Takifugu rubripes|Rep:
           Sodium/potassium/calcium exchanger 2 precursor
           (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone
           Na-Ca+K exchanger) (Solute carrier family 24 member 2).
           - Takifugu rubripes
          Length = 449

 Score =  149 bits (360), Expect = 8e-35
 Identities = 70/176 (39%), Positives = 105/176 (59%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           D+P  LFT  +R+ G +VLH    +Y+F+ALA+VCD++FVPA+  I   L +++DV    
Sbjct: 2   DYPTDLFTIEERRQGYVVLHMFGMLYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 61

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF +VIG F++  ++G+GTIVGSAVFNIL V   C + +  V+ L WWPL
Sbjct: 62  FMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGMCALFSKEVLHLTWWPL 121

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGSW 637
            RD   Y + + +LI    D  +   E+  L+S YG Y+  M ++   + F K ++
Sbjct: 122 FRDVSFYIVGLLMLIYFFLDNQITVLESVSLLSFYGCYVTFMKFNSKFERFIKSAF 177


>UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1
            (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=12;
            Euarchontoglires|Rep: Sodium/potassium/calcium exchanger
            1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Homo sapiens
            (Human)
          Length = 1099

 Score =  148 bits (358), Expect = 1e-34
 Identities = 78/210 (37%), Positives = 120/210 (57%), Gaps = 9/210 (4%)
 Frame = +2

Query: 26   ALHTTPLQNMNTS---ERDGYIRNCTPPAIDD------FPAGLFTELQRQHGAIVLHALI 178
            A+ TTP  ++ T+   E      +  PP++ D      +P  LF+  +R+ G +VLH   
Sbjct: 402  AMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFG 461

Query: 179  SIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG 358
             +Y+F+ALA+VCD+YFVPA+  I   L ++ DV            PELF ++IG FI+  
Sbjct: 462  MMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHS 521

Query: 359  DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYV 538
            ++G+GTIVGSAVFNIL V   C + +  ++ L WWPL RD   Y + + +LI    D  +
Sbjct: 522  NVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLI 581

Query: 539  QWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
             W+E+ LL+  Y  Y+  M ++K I+ + K
Sbjct: 582  AWWESLLLLLAYAFYVFTMKWNKHIEVWVK 611


>UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3;
           Euteleostomi|Rep: Retinal rod Na/Ca+K exchanger -
           Tursiops truncatus (Atlantic bottle-nosed dolphin)
          Length = 1014

 Score =  147 bits (357), Expect = 2e-34
 Identities = 68/173 (39%), Positives = 106/173 (61%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P  LF+  +R+ G +VLH    +Y+F+ALA+VCD+YFVPA+  I   L ++ DV    
Sbjct: 435 EYPRDLFSVKERRQGWVVLHIFGMLYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 494

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PELF ++IG FI+  ++G+GTIVGSAVFNIL V   C + +  ++ L WWPL
Sbjct: 495 FMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 554

Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
            RD   Y + + +LI    D  + W+E+ LL+  Y +Y+  M ++K ++ + K
Sbjct: 555 FRDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTMKWNKQLELWVK 607


>UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4;
           Caenorhabditis|Rep: Na/Ca,K-exchanger - Caenorhabditis
           elegans
          Length = 596

 Score =  147 bits (357), Expect = 2e-34
 Identities = 71/187 (37%), Positives = 112/187 (59%), Gaps = 5/187 (2%)
 Frame = +2

Query: 83  RNCTPPAID-----DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKI 247
           R+  PPA D      FP   F+  QRQ+G +VLH    IY+F++LA+VCD++FVP+++ +
Sbjct: 72  RSLAPPAPDVNDDGQFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDVL 131

Query: 248 CHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG 427
              L++++DV            PE F +VIG FI + ++G+GTIVGSA FNIL V A C 
Sbjct: 132 TEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCT 191

Query: 428 IGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607
           + +  ++ L WWPL RD   Y + +++L+    DE + + EA  + S+Y VY  +M ++ 
Sbjct: 192 LFSKSILDLTWWPLFRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVYCTVMKFNG 251

Query: 608 PIQNFAK 628
            ++   K
Sbjct: 252 QLEQLVK 258


>UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 643

 Score =  143 bits (347), Expect = 3e-33
 Identities = 68/176 (38%), Positives = 104/176 (59%), Gaps = 2/176 (1%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P   FT  Q+Q GA++ H +   Y+FLALA+ CD++FVP++  I   L +  DV    
Sbjct: 92  EYPEDEFTLEQKQQGAVICHIIGMCYMFLALAIACDEFFVPSLTVIIEKLELKEDVAGAT 151

Query: 290 XXXXXXXXPELFVNVIGTFI-TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP 466
                   PELF + IGTFI  + ++G+GTIVGSAVFN+L V   C + +  V+ L WWP
Sbjct: 152 FMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSKGVLELTWWP 211

Query: 467 LTRDCLAYGITVSILIC-IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 631
           L RDC+ Y + + ILI   +  + + W+E+ +L+  Y  Y+  M Y+  ++   KG
Sbjct: 212 LFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYVIFMKYNHNVERRIKG 267


>UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein ncx-5 - Caenorhabditis elegans
          Length = 591

 Score =  142 bits (344), Expect = 7e-33
 Identities = 64/164 (39%), Positives = 101/164 (61%)
 Frame = +2

Query: 113 FPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXX 292
           FPA +F+   R+ G +++H  + IY+F+ALAVVCD++FVP++  I   L +++DV     
Sbjct: 19  FPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEVLAISDDVAGATF 78

Query: 293 XXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT 472
                  PE F ++ G F+ + ++GVGTIVGSA FNIL V A C + +  V+ L WWPL 
Sbjct: 79  MAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHLTWWPLF 138

Query: 473 RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604
           RD   Y +++ +L+    DE ++W EA ++ S+Y  Y   M ++
Sbjct: 139 RDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAYGFFMKFN 182


>UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 209

 Score =  136 bits (329), Expect = 5e-31
 Identities = 64/135 (47%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
 Frame = +2

Query: 41  PLQNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQ-HGAIVLHALISIYLFLALAVVCD 217
           P  N +   ++   +NC  P+I DFP+   T+ QRQ  G IV H  ++IY F ALA VCD
Sbjct: 51  PSNNNSILNQETAAKNCVNPSISDFPSDFMTQYQRQKQGGIVFHVFVAIYTFAALATVCD 110

Query: 218 KYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVF 397
           +YFV ++E+IC  LN+ +DV            PE F +VIG FIT+GDIG+GTIVGSAVF
Sbjct: 111 EYFVSSLERICDGLNLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVF 170

Query: 398 NILAVAACCGIGAGM 442
           NIL + A C  G  +
Sbjct: 171 NILFIVAICAGGTAL 185


>UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias
           amurensis|Rep: Na+/Ca2+ exchanger - Asterias amurensis
           (Starfish)
          Length = 616

 Score =  135 bits (326), Expect = 1e-30
 Identities = 63/156 (40%), Positives = 95/156 (60%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           + ++ ++   LF++LA++CD +FVP++E I   L ++ DV            PELF+++I
Sbjct: 100 VTIYIILIFVLFISLAIICDDFFVPSLEAISERLELSEDVAGATFMAAGSSAPELFISII 159

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILIC 517
           G    E D+GVGTIVG+AVFNIL + A     AG V+ LDW PL RDC++YGI++   I 
Sbjct: 160 GVS-KESDVGVGTIVGTAVFNILIIIALTAALAGQVLKLDWRPLVRDCISYGISIICFII 218

Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625
              D  ++ YEA +L+ LY  YI +M  +  I N +
Sbjct: 219 FAWDGVIEIYEAIILLGLYVAYIVLMKLNSRIMNLS 254


>UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchanger
           3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3).; n=2;
           Tetrapoda|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3). - Xenopus
           tropicalis
          Length = 524

 Score =  133 bits (322), Expect = 3e-30
 Identities = 65/141 (46%), Positives = 90/141 (63%), Gaps = 2/141 (1%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           +FP  +F+   R+HGA++LH L ++Y+F ALA+VCD +FVP++EKI   L ++ DV    
Sbjct: 1   EFPDDIFSNEDRRHGAVILHVLFAMYMFYALAIVCDDFFVPSLEKISERLQLSEDVAGAT 60

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV--VPLDWW 463
                   PELF +VIG FIT+GD+GVGTIVGSAVFNIL +   CG+ AG V  + L   
Sbjct: 61  FMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVRSMLLVSL 120

Query: 464 PLTRDCLAYGITVSILICIIH 526
           P    CL Y   + I + +I+
Sbjct: 121 PSPLQCLIYTHILYIYVFLIN 141


>UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calcium
           exchanger; n=2; Eumetazoa|Rep: Testis potassium
           dependent sodium/calcium exchanger - Strongylocentrotus
           purpuratus (Purple sea urchin)
          Length = 652

 Score =  128 bits (309), Expect = 1e-28
 Identities = 64/157 (40%), Positives = 92/157 (58%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           ++ +A+  I LF+A+A++CD +FVP++E I   L+++ DV            PELF  VI
Sbjct: 114 VIFYAIFVIILFIAIAIICDDFFVPSLEVISETLSLSEDVAGATFMAAGSSAPELFTAVI 173

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILIC 517
           G    E D+GVGTIVGSAVFNIL + A     AG V+ LDW PL RD   YG+++   I 
Sbjct: 174 GVAF-ESDVGVGTIVGSAVFNILIIIALTAALAGQVLNLDWRPLARDSFFYGLSLVCFIV 232

Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
              D    W+E+ +LV LY +Y+ +M  +  I +  K
Sbjct: 233 FSWDTEFTWWESLILVILYVIYLILMKVNPIIMDKTK 269


>UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchanger
           5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5).; n=2;
           Tetrapoda|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5). - Xenopus
           tropicalis
          Length = 555

 Score =  124 bits (299), Expect = 2e-27
 Identities = 63/179 (35%), Positives = 97/179 (54%), Gaps = 1/179 (0%)
 Frame = +2

Query: 89  CTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMT 268
           C      +FP   FTE +R+ G +++H LI +Y+FLA+A+VC+ YF+P++E I   L ++
Sbjct: 7   CIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLS 66

Query: 269 NDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAV-AACCGIGAGMV 445
            DV            PE     +G F+T+GDIGV TIVGSAV+N+L + AACC +   ++
Sbjct: 67  QDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSLL 126

Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
             L  W      + +          IH +    YE+  L+ +YG+YI  M +D  I  +
Sbjct: 127 YMLKVWRYVCPWMYFS--------TIHWDAWNRYESASLILIYGIYIVTMCFDIRINQY 177


>UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n=2;
           Ostreococcus|Rep: K-independent Na+/Ca2+ exchanger JSX -
           Ostreococcus tauri
          Length = 443

 Score =  124 bits (299), Expect = 2e-27
 Identities = 59/165 (35%), Positives = 93/165 (56%), Gaps = 2/165 (1%)
 Frame = +2

Query: 146 QHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELF 325
           ++G  VL+ +  +Y+FL +A+VCD YFV ++EKIC  L ++ DV            PELF
Sbjct: 35  RNGGWVLYVVGILYMFLGIAIVCDDYFVSSLEKICDKLGLSEDVAGATFMAAGSSAPELF 94

Query: 326 VNVIGTFITEG--DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGIT 499
            + +     +   +IG+  IVGSAVFN+L +     + AG  + LDW P+TRDC+ Y + 
Sbjct: 95  SSGMSLISPDATNEIGISAIVGSAVFNMLFIVGATVLCAGCSLDLDWRPVTRDCMFYAMA 154

Query: 500 VSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGS 634
           V  ++ I +D  + WYE  + V LY  Y+  M Y+  +  +  G+
Sbjct: 155 VLTVLLIFYDGRITWYEGLICVLLYATYVLCMCYNDVLMRWMGGA 199


>UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila
           melanogaster|Rep: CG12061-PA.3 - Drosophila melanogaster
           (Fruit fly)
          Length = 353

 Score =  122 bits (295), Expect = 6e-27
 Identities = 59/122 (48%), Positives = 75/122 (61%)
 Frame = +2

Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           MT DV            PELFVN +GTF+T GDIG+GTIVGS+VFNIL +A  CGI    
Sbjct: 1   MTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-Q 59

Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622
              LDWWP+TRD   Y I ++ L  ++ D  V WYEAF L+ LY  Y+  + +D+ IQN 
Sbjct: 60  PTKLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNL 119

Query: 623 AK 628
            +
Sbjct: 120 VR 121


>UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isoform
           1; n=2; Ostreococcus|Rep: Solute carrier family 24
           member 4, isoform 1 - Ostreococcus tauri
          Length = 545

 Score =  116 bits (280), Expect = 4e-25
 Identities = 60/158 (37%), Positives = 86/158 (54%), Gaps = 2/158 (1%)
 Frame = +2

Query: 131 TELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXX 310
           TE   + G +V + +  +YLF+ +A+VCD +FV ++EKIC  L +++DV           
Sbjct: 57  TESWEKKGGLVAYFVGVVYLFIGIAIVCDDFFVASLEKICERLGLSDDVAGATFMAAGSS 116

Query: 311 XPELFVNVIGTFITEGD--IGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL 484
            PEL  + +    +  D  IGVGTIVGSAVFNIL +     I AG  + LDW PL RDC 
Sbjct: 117 APELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIGATVIFAGETLKLDWRPLARDCT 176

Query: 485 AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
            Y   +  +    +   V W+E  + V LY +YI  M+
Sbjct: 177 FYFAAIIGITLTFNGGVVNWWEGLIYVCLYMLYIAFMW 214


>UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone
           sodium-calcium potassium exchanger; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           cone sodium-calcium potassium exchanger -
           Strongylocentrotus purpuratus
          Length = 651

 Score =  113 bits (272), Expect = 4e-24
 Identities = 56/120 (46%), Positives = 75/120 (62%)
 Frame = +2

Query: 47  QNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYF 226
           Q M +    G   N T P    +P  LFT  Q++ GAIVLH ++ IY+F+ALA+VCD++F
Sbjct: 85  QGMQSVTDAGNASNNTQPNSGIYPRDLFTLQQKKDGAIVLHVILMIYMFVALAIVCDEFF 144

Query: 227 VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 406
           VPA+  I   L++++DV            PELF ++IG F    D+GVGTIVGSAVFNIL
Sbjct: 145 VPALSVITDKLDLSDDVAGATFMAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204


>UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000012714 - Anopheles gambiae
           str. PEST
          Length = 386

 Score =  113 bits (271), Expect = 5e-24
 Identities = 54/110 (49%), Positives = 68/110 (61%)
 Frame = +2

Query: 101 AIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVX 280
           ++DD P  LFTE QR  GAIVLH L +IY F+ LA VC +YF+P+VE +C  L ++ DV 
Sbjct: 2   SLDDLPPDLFTEEQRLQGAIVLHFLAAIYFFMLLAYVCSEYFLPSVECLCEDLKLSQDVA 61

Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
                      PE F N I T   + DIGVGTI+GS +FN L VAA  G+
Sbjct: 62  AATFMATATSMPEFFTNTISTLAVDSDIGVGTIMGSMLFNTLGVAALVGL 111


>UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep:
           Zgc:153443 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 231

 Score =  100 bits (239), Expect = 4e-20
 Identities = 46/96 (47%), Positives = 65/96 (67%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           ++P  LFT  QR+ GA+VLH    +Y+F+ALA+VCD++FVPA+  I   L +++DV    
Sbjct: 116 EYPEDLFTLEQRRQGAVVLHMFGMMYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 175

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVF 397
                   PELF +VIG FI+  ++G+GTIVGSAVF
Sbjct: 176 FMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211


>UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila
           melanogaster|Rep: CG17167-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 441

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 46/109 (42%), Positives = 65/109 (59%)
 Frame = +2

Query: 104 IDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXX 283
           +D+F A LFT  Q + G +VLH   ++Y F+ LA++C+ YF+P VE IC  L+++ DV  
Sbjct: 66  MDEF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAA 124

Query: 284 XXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
                     PE F N I T I E D+G+GTI+GS +FN L VA    +
Sbjct: 125 ATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAAL 173


>UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep:
           CG12061-PB.3 - Drosophila melanogaster (Fruit fly)
          Length = 110

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 48/96 (50%), Positives = 59/96 (61%)
 Frame = +2

Query: 251 HALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
           +AL MT DV            PELFVN +GTF+T GDIG+GTIVGS+VFNIL +A  CGI
Sbjct: 15  NALRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGI 74

Query: 431 GAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYV 538
                  LDWWP+TRD   Y I ++ L  ++ D  V
Sbjct: 75  FT-QPTKLDWWPVTRDTAWYLIAIASLTYVLWDSLV 109


>UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis
           pacifica SIR-1|Rep: Ca2+/Na+ antiporter - Plesiocystis
           pacifica SIR-1
          Length = 361

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 43/146 (29%), Positives = 78/146 (53%), Gaps = 3/146 (2%)
 Frame = +2

Query: 170 ALISIYL-FLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTF 346
           A++++ + F A++ V +  F+ ++++I   + +++ V            PEL   ++  F
Sbjct: 6   AIVTVLVAFYAMSAVVEGPFMASLDRIAERMGLSSSVAGATLLAFGTSAPELSTALVALF 65

Query: 347 I--TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI 520
                   GVG+IVGSA+F IL V     +       LDW P+ RD L Y +++ +LI  
Sbjct: 66  AEGAHASTGVGSIVGSAIFQILVVVGFAAVVRAST--LDWRPVIRDALFYALSIVLLIAF 123

Query: 521 IHDEYVQWYEAFLLVSLYGVYICIMY 598
           +HD+ +   EA +LV  YG+Y+ +M+
Sbjct: 124 VHDDRLTLVEAAILVGSYGLYLGVMW 149



 Score = 33.1 bits (72), Expect = 6.4
 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 7/133 (5%)
 Frame = +2

Query: 221 YFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFN 400
           + V A E I  AL +   +            PEL  +         D+ V   VGS +F+
Sbjct: 225 WLVFAAEAIAQALAVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVANAVGSNIFD 284

Query: 401 ILA-----VAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAF--L 559
           IL      V   C +  G +V L    +T   +  G T+++++ ++  +  +   AF  L
Sbjct: 285 ILVSLGLPVLLYC-LLHGDLVGLGGATITSSLVLLGATLAMVVGLLAAQRFRASRAFGAL 343

Query: 560 LVSLYGVYICIMY 598
           L+S Y  Y+   Y
Sbjct: 344 LISAYAAYVVAAY 356


>UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium
           ion/calcium ion; n=2; Ostreococcus|Rep: CaCA family
           transporter: sodium ion/calcium ion - Ostreococcus
           lucimarinus CCE9901
          Length = 603

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 11/162 (6%)
 Frame = +2

Query: 176 ISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG----- 340
           +++ LF ALA V +++FVPA+  I   L + +DV            P++F  +       
Sbjct: 95  LALTLFAALASVAERFFVPALRNIARGLALRDDVAGATLLSFGNGAPDIFAQIAALSHED 154

Query: 341 ----TFITEGDI-GVGTIVGSAVFN-ILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITV 502
                 +  G + G G  + S VF  ++ +A     G G+V  LD W   RD   Y +  
Sbjct: 155 VAESAALAVGAVTGAGAFIASFVFPCVVLIATRAASGRGLV--LDKWNFGRDVGFYAVAS 212

Query: 503 SILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628
           ++ +    D  V+ YEA  L SLY  Y+ ++   + ++ FA+
Sbjct: 213 AMALGFFLDGRVEAYEAAALFSLYAAYLFVLLSGRRLKRFAR 254


>UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+
           exchanger-like protein; n=1; Microscilla marina ATCC
           23134|Rep: Putative K+-dependent Na+/Ca+ exchanger-like
           protein - Microscilla marina ATCC 23134
          Length = 389

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 6/149 (4%)
 Frame = +2

Query: 170 ALISIYL-FLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTF 346
           AL+ I L F  +  + D++F+ +++ I   + +   V            PE+   +   F
Sbjct: 6   ALVVILLAFYVMTEIVDRHFIKSLDNIAEWMKLPPSVAGATLLALGTSAPEISTALFALF 65

Query: 347 ITEGD--IGVGTIVGSAVFNILAVAACCGIGAGMVVP---LDWWPLTRDCLAYGITVSIL 511
           +   +   GVGTIVGSA+F IL V     IG   VV    L+W P+ RD + Y  +V +L
Sbjct: 66  LEGANPATGVGTIVGSAIFQILVV-----IGFAAVVKTSYLNWRPVMRDSIFYAFSVGLL 120

Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
           I  + D      E    V  Y +Y+ +++
Sbjct: 121 ILFVADNKFTLIEGIAFVCSYFLYLFVLF 149



 Score = 34.3 bits (75), Expect = 2.8
 Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 7/148 (4%)
 Frame = +2

Query: 176 ISIYLFLALAVVCDKYF-VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           I ++L   + +    YF V A E +  A+++   +            PE+  + I     
Sbjct: 235 IPVFLLSLVIIAGASYFLVVAAEALAKAMDIPPAIIALTILAGGSSIPEMISSAIVAKQG 294

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSI------LI 514
            GD+ +   +GS +F+IL      G+   + + +   PLT D     IT SI      LI
Sbjct: 295 RGDMAIANAIGSNIFDIL---MSLGLPVLIYILIKGQPLT-DLGGANITSSIILLFTTLI 350

Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMY 598
            ++   +VQ ++A     L+ +++ ++Y
Sbjct: 351 VVVLLLFVQKFKATRPFGLFLIFLYLIY 378


>UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependent
           Na/Ca exchanger NCKX4, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to K-dependent Na/Ca
           exchanger NCKX4, partial - Strongylocentrotus purpuratus
          Length = 76

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 27/55 (49%), Positives = 38/55 (69%)
 Frame = +2

Query: 86  NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKIC 250
           NCT   I  FP G+FT  QR+ GA+V++ L+S+YL  A+  VC  YFVP++E +C
Sbjct: 21  NCTVRGISKFPRGVFTNEQRKGGALVVNFLVSLYLCGAIGYVCAAYFVPSLEILC 75


>UniRef50_UPI000155609B Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger NCKX1; n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger NCKX1 -
           Ornithorhynchus anatinus
          Length = 543

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 23/70 (32%), Positives = 42/70 (60%)
 Frame = +2

Query: 422 CGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601
           C + +  ++ L WWPL RD   Y + + +LI    D  V W+E+ LL++ Y +Y+  M +
Sbjct: 144 CALCSREILRLTWWPLFRDVSFYILDLLMLIAFFSDGTVAWWESLLLLAAYALYVFAMKW 203

Query: 602 DKPIQNFAKG 631
           ++P++ + KG
Sbjct: 204 NRPLEAWVKG 213



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 19/43 (44%), Positives = 32/43 (74%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAV 238
           ++P  +F+  +R+ G ++LH     Y+F+ALA+VCD+YFVPA+
Sbjct: 87  EYPEDVFSVEERRRGWVLLHVSGMAYVFVALAIVCDEYFVPAL 129


>UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus
           kandleri|Rep: Ca2+/Na+ antiporter - Methanopyrus
           kandleri
          Length = 329

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 29/94 (30%), Positives = 51/94 (54%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PE   ++    +   ++GVGTI+GSAV+N+  +     + AG +  L+     RD L Y 
Sbjct: 73  PEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGLAALAAGGLT-LERAVYRRDVLFYL 131

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595
           + + +++  + D  V   EA   V+LYG+Y+ +M
Sbjct: 132 LALVVVLVSLWDRVVLRVEALAWVALYGLYVLLM 165


>UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_5,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 536

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 47/176 (26%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
 Frame = +2

Query: 77  YIR-NCTPPAIDDFPAGLFTELQRQHGAIVLHA-LISIYLFLALAVVCDKYFVPAVEKIC 250
           Y++ NC    I  F    F +L      ++L A L+  +LF  LA   D Y  PAV  I 
Sbjct: 19  YVKENCNDQEIFKFTHYYFCQLDENWVILILIAPLLFFFLFNFLARTVDDYLSPAVTFIA 78

Query: 251 HALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD-IGVGTIVGSAVFNILAVAACCG 427
               M+               P+ F  V+ +   +G  I VG+I GS +     V     
Sbjct: 79  EYFKMSQTFAGVTLIAFANGVPDFFCAVLASQDDDGILIAVGSIFGSCLCMTTLVFGAVI 138

Query: 428 IGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595
           + +G ++     P  RD L  G+ + +L+       +  Y A    SLY VYI ++
Sbjct: 139 LFSG-IIKAQKVPFIRDILFNGVAIFLLMVFAFIGQINHYMAIGFCSLYLVYIVVV 193


>UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger
           antiporter; n=1; Pirellula sp.|Rep: Probable
           sodium/calcium exchanger antiporter - Rhodopirellula
           baltica
          Length = 432

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
 Frame = +2

Query: 182 IYLFLALAVV---CDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           + +FL   V+   CD + + A E I    N++  V            PELF  +I  F+ 
Sbjct: 8   VLIFLTCLVIWRACDGFEI-ASEYI--GRNLSEGVRGGTINAISSSIPELFTTLIALFVL 64

Query: 353 EG----DIGVGTIVGSAVFNILAVAACCGIGA-GMVVP--------LDWWPLTRDCLAYG 493
                  IG+GT  GSA+FN + + A C +   G VV         +    L RD ++  
Sbjct: 65  SDRDGFSIGIGTTAGSALFNGMIIPAVCILSVVGFVVMGVRVTSVNVSTRVLLRDGISLI 124

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595
           +   ILI +I+ E + W++  +L+ +Y  Y+  M
Sbjct: 125 LCEFILILLINGEQLHWWQGLILMLMYATYLVYM 158


>UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 313

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 2/153 (1%)
 Frame = +2

Query: 134 ELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXX 313
           E Q +H A+   A++     L + V   +  V     I   L ++  V            
Sbjct: 160 EEQPKHWAVDTLAIVG---GLVVLVFASRLLVDNAVSIAKELGVSEAVIGLTIVAAGTSM 216

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTR-DCLA- 487
           PEL  +++  +  + DI +G IVGS +FNIL +A  C     ++ P++   +   D L  
Sbjct: 217 PELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSC----SLIHPIEAKNVNYIDLLVM 272

Query: 488 YGITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586
            GI+V +L  +   + +   E F+L+  Y +Y+
Sbjct: 273 LGISVLLLPLVKSGQKISRTEGFVLILFYVIYM 305



 Score = 36.7 bits (81), Expect = 0.52
 Identities = 16/30 (53%), Positives = 21/30 (70%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNI 403
           PEL V++  T   +GDI +G IVGS +FNI
Sbjct: 52  PELVVSLNATLSGQGDIAIGNIVGSNIFNI 81


>UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 1117

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/143 (21%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           ++L  +  ++LF  + VV   +F P +  I   L +                P++F +  
Sbjct: 181 LLLILMWMLFLFSWVGVVASDFFCPNLSTIASRLGLNESTAGVTFLAFGNGSPDVF-STF 239

Query: 338 GTFITE-GDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILI 514
           G   T+ G + +G ++G+A F +  ++    + A   V  + WP  RD   + + V++ +
Sbjct: 240 GAMKTDSGSLAIGELLGAASFIVSVISGSMMLIAPFKV--NAWPFCRDVGFFTVAVALTL 297

Query: 515 CIIHDEYVQWYEAFLLVSLYGVY 583
             + D  ++  E   L+ LY +Y
Sbjct: 298 TFLFDGKLRRIETIALICLYLLY 320


>UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus
           ferrooxydans PV-1|Rep: Ca2+/Na+ antiporter -
           Mariprofundus ferrooxydans PV-1
          Length = 322

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 35/150 (23%), Positives = 68/150 (45%), Gaps = 6/150 (4%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           +L+   + LAL ++  +  V    +I H L +++ +            PEL  +++    
Sbjct: 172 SLLWFVVGLALLIISSRMVVWGAVEIAHLLGVSDLIIGLTIVAIGTSLPELVASLVSALK 231

Query: 350 TEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDC-LAYGITVSILICII 523
            E D+ +G ++GS +FN+LAV A    I  G   P     L RD  +  G T+++ +   
Sbjct: 232 GEADLAIGNVIGSNMFNLLAVLAMPALIHPGAFAP---EALMRDFPIMIGFTIALFVVSF 288

Query: 524 ----HDEYVQWYEAFLLVSLYGVYICIMYY 601
                   +  +E  LL + +  Y+ ++Y+
Sbjct: 289 ALKKSGGVINRFEGGLLTAGFAGYLILLYF 318


>UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr8 scaffold_150, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 593

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 31/136 (22%), Positives = 60/136 (44%), Gaps = 2/136 (1%)
 Frame = +2

Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG-TFITEGDI 364
           LF  L      YF  ++E +   L ++  +             ++F +++  T  ++GD+
Sbjct: 121 LFYLLGNTAANYFCSSLENLSRVLKLSPTIAGVTLLSLGNGAADVFASIVSFTRTSDGDV 180

Query: 365 GVGTIVGSAVFNILAVAACCGIGAG-MVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 541
           G+  ++G A F    V     I  G   + +D     RD + + I ++ L+ II    V 
Sbjct: 181 GLNIVLGGAFFVSSVVVGIISIFIGPRQISVDKPSFIRDVIFFLIALASLLVIIIIGKVS 240

Query: 542 WYEAFLLVSLYGVYIC 589
           ++ +   VS+Y  Y+C
Sbjct: 241 FWGSVCFVSIYFFYVC 256


>UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3;
           Caenorhabditis|Rep: Na/ca exchangers protein 8 -
           Caenorhabditis elegans
          Length = 703

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 31/147 (21%), Positives = 67/147 (45%), Gaps = 4/147 (2%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELF---V 328
           I++  +  I+LF+ ++ + D +F P++  I   L M+  +            P++F    
Sbjct: 105 IIVGIIYLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSIS 164

Query: 329 NVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVS- 505
           +V+ T   +  + +G + G+++F    V A         V +   P  RD + Y IT++ 
Sbjct: 165 SVLSTPKPKAALALGDLFGTSIFVTTVVLAIIIFTKSFKVAI--IPTLRDLIFYMITLAF 222

Query: 506 ILICIIHDEYVQWYEAFLLVSLYGVYI 586
           I  C +  + ++ +     + +Y VY+
Sbjct: 223 ITFCFLKFDKIEVWMPATFLGIYAVYL 249


>UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep:
           Slr0681 protein - Synechocystis sp. (strain PCC 6803)
          Length = 433

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 1/138 (0%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           +AL V+     V +   I  +L ++  V            PEL  +V+ ++  E DI VG
Sbjct: 252 VALLVLGSSLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSVVASYRGERDIAVG 311

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAYGITVSILICIIHDEYVQWYE 550
            +VGS +FNILAV     I +   + +       D  + + + +  L   I    +  +E
Sbjct: 312 NVVGSNIFNILAVLGFAAIFSPNGIQVSNSAFNFDIPVMFAVALVCLPVFITGRLIDRWE 371

Query: 551 AFLLVSLYGVYICIMYYD 604
            FL +  Y  Y   +  D
Sbjct: 372 GFLFLFYYIAYTAYLVLD 389



 Score = 39.1 bits (87), Expect = 0.097
 Identities = 15/45 (33%), Positives = 26/45 (57%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
           PE+ V++      + DI +G +VGS +FN+L +   C I   ++V
Sbjct: 119 PEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPLIV 163


>UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Halothermothrix orenii H 168|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Halothermothrix orenii H 168
          Length = 383

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 41/186 (22%), Positives = 73/186 (39%), Gaps = 2/186 (1%)
 Frame = +2

Query: 47  QNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYF 226
           Q   TS   G   N   PA  D    +   +     ++VL  +  ++  + L +   K  
Sbjct: 198 QTAATSISRGSNANQPTPAQSDVSVEI--TISEDSDSLVLR-IFKLFAGIFLVIGSSKVL 254

Query: 227 VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 406
           +PAVE     + +   +            PEL   +       G++ VG IVG+ + N+L
Sbjct: 255 IPAVEITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAVGNIVGADILNVL 314

Query: 407 AV--AACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGV 580
            V  +A      G+ VP +++ L    +   +    L     +E +   E  +L  LY +
Sbjct: 315 FVVGSAASVTAGGLNVPANFYRLQIPTMVIILVTFRLFSRGRNEEITKKEGIVLFLLYVI 374

Query: 581 YICIMY 598
           Y+ + Y
Sbjct: 375 YLILNY 380


>UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 433

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 35/170 (20%), Positives = 72/170 (42%), Gaps = 1/170 (0%)
 Frame = +2

Query: 155 AIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNV 334
           A+V+  ++ ++LF+ L +  D YF P++  I   L ++ +V            P++F + 
Sbjct: 34  ALVILFVLMLFLFIVLGITADDYFCPSLTVISKTLRLSQNVAGVTFLAYGNGAPDIF-SA 92

Query: 335 IGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILI 514
           I              +G+ +F    V     +  G    L+  P TRD L Y   VS + 
Sbjct: 93  IAAVSAHSKNPNAAQLGAGIFVTTVVVGSVTLCTG-GFHLNNRPFTRDVLFYLGAVSWMF 151

Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI-QNFAKGSWEMGIKHVQ 661
             ++ + +   EA   +  Y  Y+ ++   + + Q + +   E+  K ++
Sbjct: 152 ITMYRQRITMLEAIGFIIFYFAYVVVVIVGRYVNQRWKRRQEEVDTKFIK 201


>UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=2; Chlorobiaceae|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Chlorobium phaeobacteroides BS1
          Length = 325

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 32/127 (25%), Positives = 56/127 (44%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           LA  ++  K  V A   I  AL +   +            PEL  +++ TF  + DI VG
Sbjct: 189 LAGLLLGGKLSVDAAVGIAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVG 248

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEA 553
            +VGS +FN+L V   C     + VP++        +       + + I H + +  +E 
Sbjct: 249 NVVGSNIFNLLLVNGVCSSITQIAVPVNGGFYDLFMMILLAVFLLPMSITHKKKIVRWEG 308

Query: 554 FLLVSLY 574
            +L+++Y
Sbjct: 309 AVLLAMY 315


>UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related
           family protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
           K+-dependent Na+-Ca+ exchanger related family protein -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 325

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           L L ++  +  V     I  ALN+++ +            PEL  +++     + D+ +G
Sbjct: 180 LVLLIIASRIMVWGAVSIAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALG 239

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLAYGITVSIL 511
            IVGS +FN LAV       +G++ P    P  LTRD +   I  ++L
Sbjct: 240 NIVGSNIFNALAVVGL----SGLITPFAAEPEILTRDLVVMTIVTAVL 283



 Score = 32.7 bits (71), Expect = 8.4
 Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 5/143 (3%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340
           ++ A+ +I + L L V    +FV     +     ++  V            PE+ V+V  
Sbjct: 3   IIWAIGAIIIGLILLVKSADWFVDGAAALAKIAGLSPLVIGIVIIGFGTSAPEMIVSVTA 62

Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI 520
                  I +G   GS   NI+ +    GI A ++ P+   P+ +  ++  + + +LI +
Sbjct: 63  ALNHNSGIALGNAYGS---NIVNIGLILGISA-LIAPI---PMPKKLVSGELFILLLITL 115

Query: 521 -----IHDEYVQWYEAFLLVSLY 574
                + D+Y+   EA +++ L+
Sbjct: 116 LCFLWLQDDYISRSEALVMLVLF 138


>UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis
           thaliana|Rep: AT5g17860/MVA3_210 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 570

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
 Frame = +2

Query: 152 GAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVN 331
           G +VL A + + LF  L      YF P+++ +   L ++  +            P+LF +
Sbjct: 101 GHLVLSAWLFV-LFYLLGDTAASYFCPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSS 159

Query: 332 VIG-TFITEGDIGVGTIVGSAVF-NILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVS 505
           V+  T    GD G+ +I+G A F +   V   C +     V +D     RD +   + + 
Sbjct: 160 VVSFTRSNNGDFGLNSILGGAFFVSSFVVGTICVLIGSRDVAIDRNSFIRDVVFLLVALC 219

Query: 506 ILICIIHDEYVQWYEAFLLVSLYGVYI 586
            L  II    V  + A   +S+Y +Y+
Sbjct: 220 CLGLIIFIGKVTIWVALCYLSIYLLYV 246


>UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
           Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
           - Parvibaculum lavamentivorans DS-1
          Length = 334

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PE+  +V+  F  + DI +G +VGS +FN+L +A    +   + VP D      D    G
Sbjct: 240 PEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPVPVPADIAGF--DIWVMG 297

Query: 494 -ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595
             ++  L+       +   EA LL+  YG Y+ ++
Sbjct: 298 AASLLFLVFAWTGSRIGRVEALLLLGGYGAYVTVL 332



 Score = 33.1 bits (72), Expect = 6.4
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 4/102 (3%)
 Frame = +2

Query: 185 YLFLALAVVC----DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           YLFL + +V      ++ V     +   L ++  +            PEL  ++ G F  
Sbjct: 20  YLFLVVGLVLLLGGAEFLVKGAASLATRLGVSPFLIGLTLVGFGTSAPELVASLEGAFQG 79

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD 478
              I VG +VGS + NIL +    G+   M V  D   L RD
Sbjct: 80  YPGIAVGNVVGSNIANILLILGIAGLIFPMTV--DRGALKRD 119


>UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3;
           Poaceae|Rep: K-exchanger-like protein - Sorghum bicolor
           (Sorghum) (Sorghum vulgare)
          Length = 573

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 33/147 (22%), Positives = 64/147 (43%), Gaps = 4/147 (2%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           AL  + LF  L     +YF  ++E +  AL +   V            P++F +V+    
Sbjct: 113 ALWLVVLFYLLGDTASEYFCASLEGLSAALRLPPAVAGVTLLSLGNGAPDVFASVVSFAS 172

Query: 350 TEGD-IGVGTIVGSAVFNILAVAACCGIGAGMV---VPLDWWPLTRDCLAYGITVSILIC 517
            +G  +G+ + +G A+F    VA    +  G     V ++W    RD     + +  L+ 
Sbjct: 173 GDGGGVGLSSALGGALFVSTVVAGVVALAVGGARGGVVVEWRGFVRDLCFLLLALCYLLA 232

Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMY 598
           ++ +  +  + A   VSLY  Y+ +++
Sbjct: 233 VLVNGVITVWVAVSFVSLYVGYVVLVW 259


>UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep:
           Ca2+/Na+ antiporter - Idiomarina loihiensis
          Length = 325

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 6/165 (3%)
 Frame = +2

Query: 107 DDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXX 286
           DD  A  FTE    +   +  A++ + + L L +V  +  V     I  +L +++ V   
Sbjct: 152 DDSLAAEFTEELDSNPLPMKPAIMWLIVGLLLLIVSSRALVWGAVNIAVSLGVSDLVIGL 211

Query: 287 XXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP 466
                    PEL   +  T   E D+ +G ++GS +FN LAV    GI AG + P+   P
Sbjct: 212 TVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNMFNTLAVV---GI-AGAIEPVSLEP 267

Query: 467 --LTRDCLAYGITVSILICI----IHDEYVQWYEAFLLVSLYGVY 583
             L+RD +A  +   +L+           +     F+ + LY +Y
Sbjct: 268 LVLSRDWVAMAVLTLLLMVFGIRKARQGRINRVHGFIFICLYLLY 312


>UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Clostridium oremlandii OhILAs|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Clostridium oremlandii OhILAs
          Length = 310

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 2/157 (1%)
 Frame = +2

Query: 134 ELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXX 313
           +L RQ   ++ H L  + L +   V+   Y V A  KI   L  +               
Sbjct: 156 DLNRQSMDLI-HILFYLVLGIIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSL 214

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL   ++       DI VG I+GS +FNIL V +     + ++ P+ +       LA+ 
Sbjct: 215 PELITCLVACHKKNDDIAVGNIIGSNIFNILFVLSV----SSLISPIAFSSHLIIDLAFM 270

Query: 494 ITVSILICIIH--DEYVQWYEAFLLVSLYGVYICIMY 598
           +  + L+ I     + +   E F+L+ LY  Y   +Y
Sbjct: 271 LLFTFLLFIFSYTHKKISRLEGFVLMMLYLFYFVFIY 307


>UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=4; Proteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Desulfovibrio desulfuricans (strain G20)
          Length = 322

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340
           +  A+  + + L L VV  +  V    +I H   +++ +            PEL  ++I 
Sbjct: 170 IRRAVFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIA 229

Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLAY-GITVSIL 511
           T   E DI +G ++GS +FN LAV    GI AG + P+   P    RD +   G+T+S+ 
Sbjct: 230 TRKGEHDIALGNVLGSNLFNTLAVV---GI-AGAIHPMAIGPEVFNRDMMVMAGLTLSLF 285

Query: 512 I 514
           +
Sbjct: 286 V 286


>UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella
           pneumophila|Rep: Na/Ca antiporter - Legionella
           pneumophila (strain Corby)
          Length = 319

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/86 (26%), Positives = 40/86 (46%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           L+SI + L +  +C KY V    +I     ++               PEL  +++     
Sbjct: 173 LLSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKG 232

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGI 430
           E  I +GTI+GS ++N+L + A  G+
Sbjct: 233 EDSIAIGTIIGSNIYNLLLILALPGL 258


>UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3;
           Flavobacteriales|Rep: Sodium/calcium exchanger -
           Robiginitalea biformata HTCC2501
          Length = 315

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL-AY 490
           PEL  +VI     E  + VG ++GS +FN+LAV     I A + V LD   LTRD     
Sbjct: 218 PELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGLTAILAPVPV-LDDRLLTRDVFWML 276

Query: 491 GITVSILICIIHDEYVQ--WYEAFLLVSLYGVYI 586
           GI+  +L  +   + ++  W +  +L++ YG ++
Sbjct: 277 GISFLVLPLVFFPKGLRLGWRDGIVLLACYGAFL 310


>UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 974

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 33/148 (22%), Positives = 64/148 (43%), Gaps = 2/148 (1%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           I+    I  +LF  + +    +F P +  +   L +                P++F    
Sbjct: 79  ILFLLFILAFLFSFIGISAADFFCPNLSTVAAYLGLNESTAGVTFLAFGNGSPDVFSTF- 137

Query: 338 GTFITEGDIG--VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL 511
            + ++ G +G  VG ++G+A F +  V           VP +     RD + + I V +L
Sbjct: 138 -SAMSSGTLGLAVGELIGAASFIVSIVVGSIAFIRPFHVPKN--AFRRDVIFFTIAVLML 194

Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYICIM 595
           I  +HD ++ + E+  +V LY VY+ ++
Sbjct: 195 IVALHDGHLTFAESGSMVGLYVVYVGVV 222


>UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Mycobacterium|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 335

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 34/142 (23%), Positives = 65/142 (45%)
 Frame = +2

Query: 98  PAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277
           PA DD  A    ++    G++V +  ++I + + + VV   + V     I     +++ +
Sbjct: 166 PAGDDGAAEREPDMP-DTGSLVRYFAMTI-VGITVVVVGADWLVEGAVGIAREFGVSDAL 223

Query: 278 XXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457
                       PEL   ++ T   E DI +G ++GS+V+NI+ +     +GA  +VP D
Sbjct: 224 IGLTIVAIGTSAPELVTTIVSTVRGERDIAIGNLLGSSVYNIVLI-----LGATCLVPAD 278

Query: 458 WWPLTRDCLAYGITVSILICII 523
             PL    +   I V ++  ++
Sbjct: 279 GLPLNSSLVWIDIPVMVVATLL 300


>UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein ncx-3 - Caenorhabditis elegans
          Length = 807

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 5/96 (5%)
 Frame = +2

Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG-MVVPLDWWPLTRDCLAYG--- 493
           + ++G     GD+G GTIVGSA FN+  ++A C    G     ++ + +      +G   
Sbjct: 112 IEIVGNGFKAGDLGPGTIVGSAAFNLFCISAICVFAVGTQTKRIELYRVFVVTAFFGTFA 171

Query: 494 -ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
            I V +++ +I    V  +EA L +  + + + + Y
Sbjct: 172 YIWVFLVLIVITPNVVDVWEAILTLLFFIILVVVSY 207


>UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep:
           Uvs037 - uncultured bacterium
          Length = 354

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 8/142 (5%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           L L V+  ++ V +  ++  +  +   V            PE+  +V+ T   E DI VG
Sbjct: 178 LVLLVLGARWLVQSAVELATSWGVNEAVIGLTIVAAGTSLPEVVTSVVATIKGERDIAVG 237

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL-----ICI---IHD 529
            +VGS +FNIL V    GI +G+V P+   PL       G  + ++     +C+      
Sbjct: 238 NVVGSNIFNILCV---LGI-SGLVSPI---PLLAGEQLAGFDIPVMLGVAALCVPLFFVG 290

Query: 530 EYVQWYEAFLLVSLYGVYICIM 595
             +   E FL ++LY  Y+ I+
Sbjct: 291 AILNRMEGFLFLTLYVAYVWIL 312



 Score = 33.9 bits (74), Expect = 3.7
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL V+V   F  + ++ +  +VGS +FNIL +     + + +++      L R  +   
Sbjct: 50  PELAVSVKAAFSGQAELAIANVVGSNIFNILFILGVAALISPLIIS---HQLIRQDVPIM 106

Query: 494 ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601
           + VSI+ + +  D  +   EA +L      Y   ++Y
Sbjct: 107 VGVSIVAVLMTLDGNINKLEASILTIGLISYTWFLFY 143


>UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Chlorobium|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Chlorobium
           ferrooxidans DSM 13031
          Length = 318

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 1/136 (0%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           L L V   K  V     I  A  M   +            PEL  ++I  +    ++G+G
Sbjct: 173 LILLVTSGKLIVSGATAIALAFGMDKFLIGATVVALGTSMPELASSLIAKYRGHDEVGLG 232

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLD-WWPLTRDCLAYGITVSILICIIHDEYVQWYE 550
           TI+GS +FN L +    G+ A M+ P+      T   L  GIT  +L   + D  ++  +
Sbjct: 233 TILGSNIFNGLLIV---GVTA-MINPIQVTLRETGTALLIGITALLLTFPLSDGRIKKSQ 288

Query: 551 AFLLVSLYGVYICIMY 598
              L+ LY  Y+   +
Sbjct: 289 GVFLIMLYAGYLIFCF 304


>UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane region;
           n=1; Pseudoalteromonas atlantica T6c|Rep: Sodium/calcium
           exchanger membrane region - Pseudoalteromonas atlantica
           (strain T6c / BAA-1087)
          Length = 171

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD--WWPLTRDCLA 487
           PELFV+V      + DI +G ++G  + N+L +   C     M++PL      L RD L 
Sbjct: 20  PELFVSVNAALNNQPDIAIGNVIGRNIANVLLILGLC----AMIMPLTVATISLRRDALV 75

Query: 488 YGITVSILICIIHDEYV-QWYEAFLLVSLYGVYICIMYYDKPIQN 619
             +  S+L   +  E V  + E   L+     Y+   Y  K  Q+
Sbjct: 76  V-VAASVLCIALSSEGVTSFVEGLFLLGALAAYLTWTYLSKKGQS 119


>UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6
           precursor (Na(+)/Ca(2+)-exchange protein 6); n=2;
           Caenorhabditis|Rep: Putative sodium/calcium exchanger 6
           precursor (Na(+)/Ca(2+)-exchange protein 6) -
           Caenorhabditis elegans
          Length = 590

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 28/158 (17%), Positives = 68/158 (43%), Gaps = 4/158 (2%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELF---V 328
           I+   +  + LF+ ++   D +F P++  I   L ++  V            P++F    
Sbjct: 100 IITGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIA 159

Query: 329 NVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSI 508
           +V+ +   + D+ +G + G+ +F    V A           +  +   RD   Y + ++ 
Sbjct: 160 SVLSSPTPKADLALGELFGAGLFVTTMVLAVTIFTRPFKAEV--FSSIRDIAFYLVALAF 217

Query: 509 L-ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQN 619
           L  C ++ ++V+ +     + +Y +Y+C +   + + N
Sbjct: 218 LAFCFVYYDHVEIWMPITFLGVYLIYVCTVILSQILHN 255


>UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
           Thermotogaceae|Rep: Na+/Ca+ antiporter, CaCA family -
           Thermosipho melanesiensis BI429
          Length = 311

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
 Frame = +2

Query: 236 VEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVA 415
           V K+  +L ++               PE+ V++I T   E DI VG IVGS +FNIL + 
Sbjct: 189 VIKLAKSLGLSETFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFIL 248

Query: 416 ACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYI 586
               +   + V  D    T D +   + V IL    +  + +   E    +++Y  YI
Sbjct: 249 GVSSLVGNLYV--DVQNFTIDLIIMNLFVFILFFTSLLRKKIGKVEGIFFLTIYVFYI 304


>UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21;
           Bacteria|Rep: Na+/Ca+ antiporter, CaCA family -
           Roseiflexus sp. RS-1
          Length = 367

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 1/131 (0%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           LAL VV  ++ V           ++  V            PE+  +++     E DI VG
Sbjct: 187 LALLVVGSRWMVDGAVSFARVFGVSELVIGLTIVAVGTSLPEIATSIVAALRGERDIAVG 246

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAYGITVSILICIIHDEYVQWYE 550
            +VGS +FN+L+V     + A   + +    L  D  +   + V+ L        +  +E
Sbjct: 247 NVVGSNIFNLLSVLGLSSVVAPAGISVAPAALNFDMPVMLAVAVACLPIFFTGRLIARWE 306

Query: 551 AFLLVSLYGVY 583
            +L +  Y  Y
Sbjct: 307 GWLFLGYYIAY 317


>UniRef50_UPI00006CE59A Cluster: probable Mg2+-specific channel-like
           exchanger, putative; n=1; Tetrahymena thermophila
           SB210|Rep: probable Mg2+-specific channel-like
           exchanger, putative - Tetrahymena thermophila SB210
          Length = 625

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 32/155 (20%), Positives = 65/155 (41%), Gaps = 9/155 (5%)
 Frame = +2

Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTND----VXXXXXXXXXXXXPELFVNVIGTF 346
           +IY+F  +  +  K+F   +E I + +N   +    +            P L   +    
Sbjct: 47  TIYVFAFIYYLSVKFFNHIIEDIVYLVNYKEEEDKEIYRPLVYCVLNSIPVLAFAMCCVI 106

Query: 347 ITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP-----LDWWPLTRDCLAYGITVSIL 511
            T+ D G+  I  + + NI  +     I   + V      +D W L RD + Y + +S+ 
Sbjct: 107 RTDYDSGIMLIFSTDMINIFLIYGLILILVILPVKKEGSDIDGWQLLRDSIWYCVGLSLF 166

Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 616
           I  + +  V W+   +++  Y  +I +  Y++ I+
Sbjct: 167 IIFLFENLVTWWAGLVMICYYFSHIILQSYNETIR 201


>UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Beggiatoa sp. PS|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Beggiatoa sp. PS
          Length = 253

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 1/168 (0%)
 Frame = +2

Query: 98  PAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277
           P+ D+ P+ +    + +H  I+L  L+ I   L L V    + V     I     ++  +
Sbjct: 47  PSKDEKPSSVE---KNRHLHIILQ-LVFIVAGLGLLVQGSNWLVNGAIVIAQFYGISELI 102

Query: 278 XXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457
                       PEL   +IGTF  E ++ VG +VGS +FNIL V     + + + + + 
Sbjct: 103 IALTVISIGTSLPELATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPISIDVS 162

Query: 458 WWPLTRDCLAYGITVSI-LICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
              +  D +   I V+I  + I  +  ++ +E  L ++ Y  Y   ++
Sbjct: 163 QAAIFLD-MPVMIAVAIACLPIFFNNLIERWEGGLFLAYYIAYTLYLF 209


>UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=5; Bacteria|Rep: K+-dependent Na+/Ca+
           exchanger related-protein - Pseudomonas stutzeri (strain
           A1501)
          Length = 361

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 35/117 (29%), Positives = 48/117 (41%)
 Frame = +2

Query: 98  PAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277
           PA DD  A  F   +       +  L+ I L L L V      +     +  AL ++  V
Sbjct: 154 PAGDDEFATEFGPDESDKPFAWVFQLLLILLGLGLLVGGSNLLIEGAVGLARALGLSELV 213

Query: 278 XXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
                       PEL  +V+     E DI VG +VGS +FN+L V     +GAG  V
Sbjct: 214 IGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLV-----LGAGAAV 265



 Score = 33.9 bits (74), Expect = 3.7
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
           PE  V+V  +    GDI VG ++GS + NIL +     + A +VV
Sbjct: 53  PETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALIAPLVV 97


>UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1;
           Arabidopsis thaliana|Rep: Na/Ca,K-exchanger-like protein
           - Arabidopsis thaliana (Mouse-ear cress)
          Length = 559

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 5/143 (3%)
 Frame = +2

Query: 182 IYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG- 358
           + LF  L     +YF  ++E +   LN++  V            P+LF +++ +F+ E  
Sbjct: 100 LLLFYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFASLV-SFMGESK 158

Query: 359 ---DIGVGTIVGSAVFNILAVAACCGIGA-GMVVPLDWWPLTRDCLAYGITVSILICIIH 526
              D+G+ T+VG + F    V     I      V ++     RD   +   +  L  I+ 
Sbjct: 159 GTYDVGLNTVVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCAAIGSLALILV 218

Query: 527 DEYVQWYEAFLLVSLYGVYICIM 595
              + ++ A    SLY VY+  +
Sbjct: 219 YGKINFWGALGFCSLYAVYVAFV 241


>UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Na+/Ca+
           antiporter, CaCA family - Halorubrum lacusprofundi ATCC
           49239
          Length = 326

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 27/98 (27%), Positives = 44/98 (44%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL V V       G+IGVG I+GS  +N+  +     +    V+P++   + RD  A  
Sbjct: 57  PELVVTVDAALAGLGEIGVGNIIGSNAYNLAFILG--AVSLLRVIPVERSLVHRDGAALV 114

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607
           ++  +    + D  V   E  LL  L+  Y   +  D+
Sbjct: 115 LSTLVGAAALFDRTVTGVEGALLAGLFVAYTAYLVRDE 152



 Score = 33.9 bits (74), Expect = 3.7
 Identities = 19/73 (26%), Positives = 33/73 (45%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           LAL +V   + V A   +  +  +++              PEL V+++        + VG
Sbjct: 189 LALVLVSGHFMVEAASTLARSAGVSDWAIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVG 248

Query: 374 TIVGSAVFNILAV 412
            +VGS VFN+L +
Sbjct: 249 NVVGSNVFNVLGI 261


>UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; Marinomonas|Rep: Na+/Ca+ antiporter, CaCA family
           precursor - Marinomonas sp. MWYL1
          Length = 332

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 6/168 (3%)
 Frame = +2

Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289
           D    L   L    G+ V  +LI   + LA+ +   K  V     I  AL ++  V    
Sbjct: 161 DLEKDLKEGLPEDDGSSVSKSLIIALIGLAVLIGSSKLLVWGAIGIATALGVSELVIGLT 220

Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469
                   PEL  +V        DI +G I+GS +FN+  V     + A  +V  D   +
Sbjct: 221 IVAVGTSLPELAASVSSVRKGHHDIAIGNILGSNIFNLATVLPLPALLAPGLV--DQSVI 278

Query: 470 TRDC-LAYGITVSILICII-----HDEYVQWYEAFLLVSLYGVYICIM 595
           +RD     G+TV++ + I       +  +  +    L++ YGVY+ I+
Sbjct: 279 SRDFPWVLGLTVALALAIFIFKKTKNNSIPRWVGLPLIASYGVYLFII 326


>UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
           Rhodobacter sphaeroides|Rep: Na+/Ca+ antiporter, CaCA
           family - Rhodobacter sphaeroides (strain ATCC 17029 /
           ATH 2.4.9)
          Length = 305

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           L + +V  +  V +  +I  +  ++  V            PEL  + I  +    +I VG
Sbjct: 171 LVVLMVGARLLVDSSTQIARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVG 230

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLAYGITVSILICIIHD--EYVQ 541
            ++GS +FN+L +    GI  G+V+P+        R+ + + +  S+L+ ++    + V 
Sbjct: 231 NVIGSNIFNVLGI---LGI-TGLVLPIQGLDPRFLREDMPWVLGCSLLLVLMAFALKGVP 286

Query: 542 WYEAFLLVSLYGVYICIM 595
            +   LL++ YG Y+ +M
Sbjct: 287 RWAGALLLAAYGGYVALM 304


>UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091;
           n=9; Methanococcales|Rep: Uncharacterized membrane
           protein MJ0091 - Methanococcus jannaschii
          Length = 302

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 31/133 (23%), Positives = 58/133 (43%)
 Frame = +2

Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367
           L L L      +FV   E+I    N++N V            PE+  +   +++    I 
Sbjct: 11  LGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGIS 70

Query: 368 VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWY 547
           +G  +GS + NI  V     I + ++V  +   L ++ L Y + V I   +I  +   W 
Sbjct: 71  IGNAIGSCICNIGLVLGLSAIISPIIVDKN---LQKNILVYLLFV-IFAAVIGIDGFSWI 126

Query: 548 EAFLLVSLYGVYI 586
           +  +L+ L+ +Y+
Sbjct: 127 DGVVLLILFIIYL 139


>UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Putative
           uncharacterized protein - Candidatus Kuenenia
           stuttgartiensis
          Length = 318

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 29/95 (30%), Positives = 49/95 (51%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL ++ +  F  E DI VG ++GS ++NILAV    GI A ++ PL    +    L + 
Sbjct: 220 PELAISTVAAFRKESDICVGNVLGSNIYNILAV---LGITA-IIHPLQ---INTSSLQFD 272

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
           + V I+  ++    +     F+L    GV++ + Y
Sbjct: 273 MPVMIVFSLLLIPMIM--RKFILTRWEGVFLLVGY 305


>UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Silicibacter sp. TM1040|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Silicibacter sp. (strain TM1040)
          Length = 327

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 30/135 (22%), Positives = 55/135 (40%)
 Frame = +2

Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           L L VV     V     +  +  ++  V            PEL  +VI     +GD+  G
Sbjct: 192 LVLVVVGGAALVNGAVALARSFEISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFG 251

Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEA 553
            +VGS ++NIL +     + A   +P D        +   ++   ++       V   E 
Sbjct: 252 NVVGSNIYNILGIGGTTALIAPSDLPGDILRFDAPVMIL-VSAGFVLFAATGFRVGRREG 310

Query: 554 FLLVSLYGVYICIMY 598
            +L++ YG+YI +++
Sbjct: 311 AILLAGYGLYIWMIW 325


>UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4;
           Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
           - Methanosarcina acetivorans
          Length = 350

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 33/144 (22%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           + ++ L  A  V+  KYFV         L + + V            PEL V V      
Sbjct: 208 IFTLVLSCAAIVIGAKYFVEESIFFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQG 267

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGM-VVPLDWWPLTRDCLAYGITVSILICIIHD 529
            G I +G ++GS + NI  +    G+   + V  +  +  T   +A  I++ +LI I   
Sbjct: 268 YGSIALGNVIGSNITNIFLILGLSGLFYPLSVAEMSLFFTTPVMIA--ISLILLIFISTG 325

Query: 530 EYVQWYEAFLLVSLYGVYICIMYY 601
             ++ +E  +L+  Y  ++ +++Y
Sbjct: 326 WEIKRWEGVVLMMFYVAFLVVLFY 349



 Score = 37.9 bits (84), Expect = 0.22
 Identities = 33/147 (22%), Positives = 57/147 (38%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           I ++ LI + L L   V    YFV +   I   L ++  V            PEL  ++ 
Sbjct: 2   ITVNFLI-LLLGLVFLVKGSDYFVKSASTIAKKLGVSEFVIGLTLVAIGTSIPELASSIA 60

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILIC 517
            +      I +G +VGS + N+  +     + + M   +D   L RD      +  +   
Sbjct: 61  ASIQQASGIVIGNVVGSNIANVGLIVGVAALLSPMKTEIDM--LKRDGYIMLFSAVLFFV 118

Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMY 598
              +  +   EA L V LY  Y+  ++
Sbjct: 119 FAFNRELSMLEAGLFVLLYIAYVFFLF 145


>UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:
           NEQ486 - Nanoarchaeum equitans
          Length = 308

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 38/148 (25%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           LI + LF  L    DK F+ + E+I  +L + + +            PEL V ++     
Sbjct: 11  LILVSLFFLL-FGADK-FLESGERISKSLGIDDRLLGLILVSISTSLPELAVAILAALDN 68

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PL--DWWPLTRDCLAYG-ITVSILICI 520
           + +I +G I+GS   N+       G+G G+++ PL      L  +   +G IT++ L+ I
Sbjct: 69  KSEIVLGDIIGSNFANL-----GLGLGIGLIISPLVIKKETLFNEVPIHGAITLATLLLI 123

Query: 521 IHDEYVQWYEAFLLVSLYGVYICIMYYD 604
           ++D  +  YEA  ++  + + +  +Y D
Sbjct: 124 LNDSVLDKYEALTILIFFALMLLNIYKD 151


>UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45;
           Proteobacteria|Rep: Sodium-calcium exchanger - Vibrio
           fischeri (strain ATCC 700601 / ES114)
          Length = 323

 Score = 40.7 bits (91), Expect = 0.032
 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRD-CL 484
           PEL  +V G    E D+  G I+GS VFNILAV    GI A ++ P +  P  + RD  +
Sbjct: 225 PELAASVAGVLKGEDDMAAGNIIGSNVFNILAV---MGIPA-LINPSEISPDLMGRDFYV 280

Query: 485 AYGITVSILICII-HDEYVQWYEAFLLVSLYGVY 583
             G+++ +LI  +     +   E  +LV+ + VY
Sbjct: 281 MLGVSILLLIMALGKSRSINRIEGGILVTCFCVY 314



 Score = 39.1 bits (87), Expect = 0.097
 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD-WWPLTRDCLAY 490
           PE+ V+       + D  VG ++GS   NI  +A   GI A ++ PL     + R  L  
Sbjct: 55  PEMMVSAAAALDGKTDTAVGNVIGS---NIANIALILGITA-LIKPLAISSAIIRRELPL 110

Query: 491 GITVSILI-CIIHDEYVQWYEAFLLVSLYGVYICIMYY 601
            + V++L   I+ + Y+ +YE  LL+ L+  +I  M Y
Sbjct: 111 MLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLY 148


>UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=11; Proteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Azotobacter vinelandii AvOP
          Length = 360

 Score = 40.7 bits (91), Expect = 0.032
 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
 Frame = +2

Query: 131 TELQRQ-HGAIVLHA-LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXX 304
           TE  R+  G + L   L  + L LA+ V      + A   +  AL ++            
Sbjct: 162 TEFGRKPEGRLALPGHLALVALGLAMLVWGSDLLIDATVTLARALGLSELAIGLTMVAAG 221

Query: 305 XXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412
              PEL  +++     E DI VG IVGS +FN+LAV
Sbjct: 222 TSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAV 257



 Score = 36.3 bits (80), Expect = 0.69
 Identities = 22/70 (31%), Positives = 40/70 (57%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PE+ V+V      +GDI VG  +GS +FN+L +    G+ A +V+PL    ++R  + + 
Sbjct: 53  PEMAVSVRSASGGQGDIAVGNAIGSNIFNVLMI---LGLSA-LVIPL---RVSRQLIRFD 105

Query: 494 ITVSILICII 523
           + V I + ++
Sbjct: 106 VPVMIGVSLL 115


>UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger protein;
           n=1; Clostridium tetani|Rep: Putative sodium/calcium
           exchanger protein - Clostridium tetani
          Length = 347

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
 Frame = +2

Query: 359 DIGVGTIVGSAVFNILAVAACCGI---GAGMVVPLDWWPLTRDCLAYGITVSILICIIHD 529
           D+GV TI GS VFNIL +         G  +++ +D   + RD + Y + +  L+   + 
Sbjct: 79  DVGVPTIAGSGVFNILIIPMATIFAYRGKDLLIKVDKKVVYRDMIFYTMAIGALVFFTYL 138

Query: 530 EYVQWYEAFLLVSLYGVYICIMY 598
                +   +LV +Y  YI ++Y
Sbjct: 139 GSYTVFAGIVLVLIYIGYIFVLY 161


>UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 305

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 1/142 (0%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           L+ I  F+ L    D +FV     +   L + + +            PE  V++      
Sbjct: 4   LLLIIGFVLLIKGAD-FFVEGSSSLARFLKIPSVIIGLTIVAMGTSAPEASVSINAALAG 62

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI-IHD 529
             DI V  I+GS +FN L V   C   +G     D   L RD +   I +++++CI I +
Sbjct: 63  NNDIAVSNIIGSNIFNGLIVVGICAFISGFKTNKD--ILKRD-MPVNILITVILCIMIAN 119

Query: 530 EYVQWYEAFLLVSLYGVYICIM 595
             +   E  LL++    YI  M
Sbjct: 120 GKLSRIEGILLLAGMIFYILNM 141


>UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23;
           Gammaproteobacteria|Rep: Ca2+/Na+ antiporter - Vibrio
           vulnificus
          Length = 321

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 20/39 (51%), Positives = 24/39 (61%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
           PEL  ++ G    E D+ VG I+GS VFNILAV    GI
Sbjct: 222 PELAASLAGALKGEDDMAVGNIIGSNVFNILAVMGIPGI 260


>UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=8; Bacteroidales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 317

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 28/99 (28%), Positives = 48/99 (48%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           ++L+ L+ I + LAL V    +       I     +++ V            PEL V+++
Sbjct: 1   MILNILLLI-IGLALVVGGANFLTDGAASIAKRFRLSDLVIGLTVLAFGTSAPELTVSLM 59

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL 454
                  DI +G ++GS +FNILA+    GI A +++PL
Sbjct: 60  AALKGSADIAIGNVIGSNIFNILAIV---GITA-LIMPL 94


>UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep: Na+/Ca+
           antiporter, CaCA family - Fervidobacterium nodosum
           Rt17-B1
          Length = 314

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 23/97 (23%), Positives = 46/97 (47%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           ++L  L+ I  F+ +++  DK  V     +   L +++ +            PEL VN++
Sbjct: 1   MILSILLLIIGFVFVSIGSDK-LVEGASTLAKKLKVSDLLIGLTIVAFGTSAPELAVNIV 59

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
            +     +I +G ++GS +FNIL V     +   ++V
Sbjct: 60  SSIKGTSNISLGNVIGSNIFNILVVVGLSAVIRPVIV 96



 Score = 37.1 bits (82), Expect = 0.39
 Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 1/155 (0%)
 Frame = +2

Query: 140 QRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPE 319
           ++Q G I+  +++ I   LA  V   ++ V     I  A  +++ +            PE
Sbjct: 164 EKQLGTII--SILYIIGGLAGLVFGGRWIVNGAVDIAKAFGVSDKLIGLTIVAAGTSIPE 221

Query: 320 LFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP-LTRDCLAYGI 496
           L  ++        +I +G  VGS +FN+  +    GI A ++ P+ +   L  D     I
Sbjct: 222 LATSLAAIIKGNNEIALGNAVGSNIFNVFFI---LGISA-VIKPIVYTTVLNFDVTLLVI 277

Query: 497 TVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601
              IL+    +  ++ +E  L+VS Y  Y   + Y
Sbjct: 278 ITVILLLFSKNLKIEKFEGLLMVSTYVGYTIYLIY 312


>UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;
           Loktanella vestfoldensis SKA53|Rep: Putative
           sodium/calcium exchanger - Loktanella vestfoldensis
           SKA53
          Length = 305

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 34/113 (30%), Positives = 50/113 (44%), Gaps = 2/113 (1%)
 Frame = +2

Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367
           L L   +V   Y V +   I     ++  +            PEL   V+     E DI 
Sbjct: 168 LGLVTVMVGAHYLVQSASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMAAIRGERDIA 227

Query: 368 VGTIVGSAVFNILAVAACCGIGAGMV-VPLDWWPLTRDC-LAYGITVSILICI 520
           +G IVGS +FNILA+    GI A +  +P+D   L  D  +  GIT+ +L  +
Sbjct: 228 LGNIVGSNIFNILAI---LGITAVVTPIPVDARFLNVDTPVVIGITLLLLALV 277


>UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2;
           Hyphomonadaceae|Rep: Sodium/calcium exchanger -
           Oceanicaulis alexandrii HTCC2633
          Length = 334

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 31/140 (22%), Positives = 55/140 (39%), Gaps = 13/140 (9%)
 Frame = +2

Query: 107 DDFPAGLFTELQRQHGAIVLHALISIYLF--LALAVVCDKYFVPAVEKICHALNMTNDVX 280
           DD      T+++   G      +++++L   L +  +  +  V     I    N+ + V 
Sbjct: 155 DDPMIAELTDIEHMDGLPAKAPMVALFLLGGLVMLPIGAQLIVDGGVGIAALFNVPDAVI 214

Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV----- 445
                      PEL   ++     + D+ +G +VGS +FNI AV    G+ A        
Sbjct: 215 GLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGLAASFATGQPA 274

Query: 446 ------VPLDWWPLTRDCLA 487
                 + LD+W +T   LA
Sbjct: 275 PVSDQFIQLDFWVMTAAALA 294


>UniRef50_Q9HS69 Cluster: Cation antiporter; n=2;
           Halobacteriaceae|Rep: Cation antiporter - Halobacterium
           salinarium (Halobacterium halobium)
          Length = 318

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAY- 490
           PEL  +V+     E D  +G +VGS ++N+LAV    GI A ++VP+    +T+  LA+ 
Sbjct: 224 PELATSVVSALRDEADFSIGNVVGSNIYNVLAV---IGIVA-ILVPI---TVTKGTLAFE 276

Query: 491 -----GITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586
                G TV  L  +   + +   E  +L+  YG ++
Sbjct: 277 LPVMLGFTVLALGMMAVGDRITRVEGAVLIGSYGGFV 313


>UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           Na(+)/Ca(2+) antiporter - Uncultured methanogenic
           archaeon RC-I
          Length = 308

 Score = 39.9 bits (89), Expect = 0.056
 Identities = 29/138 (21%), Positives = 60/138 (43%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           L+ + + +A  ++  K  V +   + +A  ++  +            PE+   ++ +   
Sbjct: 166 LVLLAIGIACVILGGKVTVDSAVSLANAFQVSPFLIAVTIIAIGTSMPEMVTALVASRKD 225

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDE 532
           EGD+ +G  +GS + N L +       A +V PL    +    +  GI V +L  ++   
Sbjct: 226 EGDLVMGNCIGSVIVNTLFILG----AAAIVSPLPIAGVIDILILLGIIVLLLPILVTRS 281

Query: 533 YVQWYEAFLLVSLYGVYI 586
            +   E  LLV LY +++
Sbjct: 282 QIGHREGILLVVLYVIFV 299


>UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
           n=1; Sulfurovum sp. NBC37-1|Rep: Calcium:H+/Na+
           antiporter, CaCA family - Sulfurovum sp. (strain
           NBC37-1)
          Length = 310

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 27/122 (22%), Positives = 52/122 (42%)
 Frame = +2

Query: 239 EKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAA 418
           EKI    N+   +            PE+  ++  +   + +I +  ++GS + NI  V A
Sbjct: 25  EKIALKFNIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLA 84

Query: 419 CCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
              + A  + P   +   +D     + V + I +I D  +  ++A LL+ L G Y+  + 
Sbjct: 85  SVFLIARNISPKRDF-FAKDSTWALVPVLVFILMILDGVISRFDAVLLLLLMGAYLLFLL 143

Query: 599 YD 604
            D
Sbjct: 144 QD 145


>UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 336

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 25/101 (24%), Positives = 44/101 (43%)
 Frame = +2

Query: 155 AIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNV 334
           A+V+  LI  ++FL        +FV     I   L + + +            PE  V+V
Sbjct: 11  ALVIMFLIIGFVFLIKGA---DFFVEGSSSIAKKLKVPSIIIGLTIVAMGTSLPETAVSV 67

Query: 335 IGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457
             + +   ++ V  +VGS +FN++ V   C I   ++V  D
Sbjct: 68  TASLVHNNELAVSNVVGSNIFNLMFVIGVCAIMTPIMVQKD 108



 Score = 36.3 bits (80), Expect = 0.69
 Identities = 29/119 (24%), Positives = 48/119 (40%)
 Frame = +2

Query: 227 VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 406
           V A  +I   L M+  +            PEL  +V+     E D+ VG  VGS +FNIL
Sbjct: 213 VDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSVVAARKNEVDMAVGNAVGSNIFNIL 272

Query: 407 AVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVY 583
            V       + M +  +   +    +  G +V +      D  +   E   +V++Y +Y
Sbjct: 273 MVLGIASAISPMSLISE--NVIDILVLVGFSVVVWFFARSDRKITRNEGIAMVAMYLIY 329


>UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein
           precursor; n=3; Gammaproteobacteria|Rep: Na+/Ca+
           antiporter, CaCA family protein precursor - Psychromonas
           ingrahamii (strain 37)
          Length = 320

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 23/84 (27%), Positives = 37/84 (44%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340
           VL  +I++ L L L +   +  +     I    N+   V            PEL ++VI 
Sbjct: 171 VLWTIIAVVLGLLLLIGGSQVLLIGAIGIAEHFNVPEAVIGLTLVAIGTSLPELSISVIA 230

Query: 341 TFITEGDIGVGTIVGSAVFNILAV 412
                 D+ VG I+GS +FN+L +
Sbjct: 231 AIRRHADVAVGNILGSNIFNLLGI 254



 Score = 37.5 bits (83), Expect = 0.30
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT-RDCLAY 490
           PEL V+V      + DI +G +VGS + NIL +   C +    + PL   PL  R   A 
Sbjct: 51  PELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGICAV----ITPLAVKPLVLRRDAAT 106

Query: 491 GITVSILICII 523
            +  SIL  I+
Sbjct: 107 VVAASILFLIL 117


>UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; sulfur-oxidizing symbionts|Rep: Na+/Ca+ antiporter,
           CaCA family precursor - Ruthia magnifica subsp.
           Calyptogena magnifica
          Length = 317

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 25/96 (26%), Positives = 54/96 (56%), Gaps = 5/96 (5%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL V++      +  + +G ++GS +FN +AV A  G+     VP++   ++RD     
Sbjct: 221 PELAVSITSVLKKQYAMVIGNVIGSNLFNTIAVLAIPGLIHPSDVPVE--VISRD-YPVM 277

Query: 494 ITVSILICIIHDEY-----VQWYEAFLLVSLYGVYI 586
           + ++IL+ I+  ++     +  ++ F+L+ ++G+YI
Sbjct: 278 LLLTILLFIVSYKFNKKHIINRFKGFVLIGMFGLYI 313


>UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na/Ca
           exchanger - Aedes aegypti (Yellowfever mosquito)
          Length = 583

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 33/152 (21%), Positives = 67/152 (44%), Gaps = 3/152 (1%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           + L   + I  F  LA   D++F P +  I   L+++  V            P+LF   +
Sbjct: 77  VALLTFMLILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLF-TAV 135

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PLDWW--PLTRDCLAYGITVSI 508
                + ++  G ++G+ +F +  VA     G  +V+ P   +   + RD + +   VS 
Sbjct: 136 SNPNDDTELMFGELLGAGLFVVGIVA-----GTILVIRPFHVYSAAVVRDVVFFIFAVSW 190

Query: 509 LICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604
           +    +DE     +A ++V +Y +Y+ ++  D
Sbjct: 191 ITVCAYDERFTLSDAIVVVVVYVLYLVVVLID 222


>UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1;
           Haloarcula marismortui|Rep: Na+/Ca2+-exchanging protein
           - Haloarcula marismortui (Halobacterium marismortui)
          Length = 335

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = +2

Query: 188 LFLALAVVC--DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI-TEG 358
           + +A AV+     YF  A E++     +   V            PE+   VI T I  E 
Sbjct: 11  IIVATAVIWKGSAYFERAAERLSKYYGLPVAVHGAIVVAVGSSFPEISSVVISTVIHDEF 70

Query: 359 DIGVGTIVGSAVFNILAVAACCGIGA 436
            +GVG IVGSA+FN+L + A   + +
Sbjct: 71  SLGVGAIVGSAIFNLLVIPALAALSS 96


>UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamma
           proteobacterium HTCC2207|Rep: Putative Ca2+/Na+
           antiporter - gamma proteobacterium HTCC2207
          Length = 330

 Score = 39.1 bits (87), Expect = 0.097
 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
 Frame = +2

Query: 152 GAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVN 331
           GA  L  ++ + + LA A V     V + + I  +L ++  +            PEL  +
Sbjct: 171 GAAALWFIVGLAVLLASAEVT----VWSAKTIAQSLGISELIIGLTVVAIGTSLPELAAS 226

Query: 332 VIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PLDWWPLTRDCLAYGITVSI 508
           V+       DI +G + GS +FN++ V    GI + M + P+      RD  +  I   +
Sbjct: 227 VVSAMRGHHDIAIGNVFGSNLFNLMLVMPAAGIISPMTISPM---VFNRDFASLAIMTLL 283

Query: 509 LICII 523
           LI ++
Sbjct: 284 LIAMV 288


>UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2;
           Oscillatoriales|Rep: Sodium-calcium exchanger - Lyngbya
           sp. PCC 8106
          Length = 315

 Score = 39.1 bits (87), Expect = 0.097
 Identities = 30/139 (21%), Positives = 62/139 (44%), Gaps = 1/139 (0%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           +I + +  A   +   + + ++ KI   L +  ++            PEL V    +   
Sbjct: 173 IIVLLICTACMFLGANFTIQSIIKIADILGIGKELIAISAVALGTSLPELAVTFSASRRG 232

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICII-HD 529
           + ++ +G ++GS +FN L V    G+   +++P D   + RD L   +  ++L   +  D
Sbjct: 233 DAEVAIGNVLGSNIFNSLIVMGVPGLFEDLIIP-D--IIIRDGLPMLLASTLLFFFVTQD 289

Query: 530 EYVQWYEAFLLVSLYGVYI 586
           + V  +E +L   LY  +I
Sbjct: 290 KKVTKWEGWLFFVLYAWFI 308


>UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Rep:
           F15I1.21 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 644

 Score = 39.1 bits (87), Expect = 0.097
 Identities = 45/204 (22%), Positives = 88/204 (43%), Gaps = 8/204 (3%)
 Frame = +2

Query: 8   SSVACVALHTTPLQNMNTSERDGYIRN---CTPPAIDDFPAGLFTELQ--RQHGAIVLHA 172
           S+V+C  LH    ++   +++  ++++   C+P    D+    +   +  +  G I+L  
Sbjct: 87  STVSCSGLH----EHRGYADQCEFLKSNPICSPDGFFDYLKFFYCSCRDFKILGYILLGV 142

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI- 349
            + + LF  L      YF  ++EK+   L +   V            P++F + I  F+ 
Sbjct: 143 WL-VALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS-IAAFVG 200

Query: 350 -TEGDIGVGTIVGSAVFNILAVAACCGI-GAGMVVPLDWWPLTRDCLAYGITVSILICII 523
             +G++G+ +++G AVF    V     +  A   V +D     RD   +  T+  L+ I+
Sbjct: 201 SDKGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSFFLFTLVALMVIL 260

Query: 524 HDEYVQWYEAFLLVSLYGVYICIM 595
               V    A   VS+Y  Y  ++
Sbjct: 261 MVGKVTVGIAIAFVSIYVFYASLV 284


>UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Pseudomonas syringae group|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Pseudomonas syringae pv. phaseolicola (strain 1448A /
           Race 6)
          Length = 343

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           P L  ++I  F  E DI VG ++GS +FN+L V     + A + + +    +  D L   
Sbjct: 208 PALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGVTALFAPVPLTVSPNAMVFD-LPIM 266

Query: 494 ITVSIL-ICIIHDEY-VQWYEAFLLVSLYGVY 583
           + VS+L + + +  Y +   E   L+SLY  Y
Sbjct: 267 LGVSLLCVPLFYSGYRIDRMEGVFLLSLYLTY 298



 Score = 37.1 bits (82), Expect = 0.39
 Identities = 19/70 (27%), Positives = 36/70 (51%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           P++ V++   F    DI VG+++G  +FN+L +   C     +++PL    + R  L   
Sbjct: 45  PQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLC----ALIIPL---RVARQVLHID 97

Query: 494 ITVSILICII 523
           I + I  C++
Sbjct: 98  IPLMIGACLL 107


>UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like
           protein; n=1; Salinibacter ruber DSM 13855|Rep:
           K+-dependent Na+/Ca+ exchanger-like protein -
           Salinibacter ruber (strain DSM 13855)
          Length = 317

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDC-L 484
           PE  VNV      E  + +G I+GS + N+  +   C +    V+PL   P  L R+  +
Sbjct: 52  PEYLVNVFALISGESPLAIGNIIGSNISNVALILGACAV----VLPLAVTPEVLRREYPV 107

Query: 485 AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604
             G+ V   +C + D  +   +  L+V L       ++YD
Sbjct: 108 MLGVMVLFYLCAL-DGVIGARDGVLMVVLLSGLAAYVFYD 146



 Score = 35.9 bits (79), Expect = 0.91
 Identities = 20/68 (29%), Positives = 31/68 (45%)
 Frame = +2

Query: 245 ICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424
           I   LN+ + V            PEL  +++GT   E D+ VG ++GS + N+L V    
Sbjct: 200 ISDVLNIDHVVIGLTVVAIGTSLPELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVGTL 259

Query: 425 GIGAGMVV 448
            I   + V
Sbjct: 260 AIAEPITV 267


>UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sodium/calcium
           exchanger - Lentisphaera araneosa HTCC2155
          Length = 319

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 20/77 (25%), Positives = 34/77 (44%)
 Frame = +2

Query: 182 IYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD 361
           I+  LA        FV     I   L ++  V            PEL  +++ +    GD
Sbjct: 176 IFAGLAGVTYGGSIFVDGASTIAAGLGVSQAVIGLTIVALGTSLPELAASIMASLKGHGD 235

Query: 362 IGVGTIVGSAVFNILAV 412
           + +G ++GS +FN+LA+
Sbjct: 236 MALGNVIGSCIFNLLAI 252


>UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=3; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Stappia aggregata
           IAM 12614
          Length = 337

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP-----LDWWPLTRD 478
           PEL   V+      G + +G ++GS VFN+LA+     +   + VP     LD W +   
Sbjct: 238 PELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIGITAVIVPIDVPQEVLKLDIWVMLAC 297

Query: 479 CLAYGITVSILICI 520
            +   I   + IC+
Sbjct: 298 AILLTILAGMRICL 311


>UniRef50_Q5CI48 Cluster: Cation exchanger; n=2;
           Cryptosporidium|Rep: Cation exchanger - Cryptosporidium
           hominis
          Length = 940

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 30/151 (19%), Positives = 65/151 (43%), Gaps = 8/151 (5%)
 Frame = +2

Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG 358
           S  LF+A   V D Y    + K+   L++++               ++ + +I   I E 
Sbjct: 109 SCILFIACGTVADTYISSLMIKLAECLSLSDTFAGSTLLAFSNAASDVILGIISVSIGEK 168

Query: 359 ---DIGVGTIVGSAVFNILAVAACCGIGA-----GMVVPLDWWPLTRDCLAYGITVSILI 514
              D+ +G ++G+ +F IL V  C  + +        + +  +   RD +A  I +  L+
Sbjct: 169 DAVDVFLGDVIGACLFIILVVFGCVMVFSKSSENSNYINIPIFNHLRDTIALTIGLIQLL 228

Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607
            I H  ++    + + +  YG Y+ ++ + +
Sbjct: 229 IIHHLGFISSKMSVIPLIAYGFYVLLLQWSE 259


>UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Methanoculleus marisnigri JR1|Rep: Na+/Ca+ antiporter,
           CaCA family - Methanoculleus marisnigri (strain ATCC
           35101 / DSM 1498 / JR1)
          Length = 311

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 30/101 (29%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL  +++     EG I +G I+GS +FN+L V    GI   ++ P+    L    +   
Sbjct: 215 PELATSIVAAARDEGSISIGNILGSNIFNLLLV---LGISL-LLAPVTVGSLVDIAVVVL 270

Query: 494 ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613
            +V+IL +       V+ + A LL+  Y  YI   +   PI
Sbjct: 271 FSVAILPLLFARPSVVRGWSALLLLG-YAAYIAWSFGAVPI 310


>UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protein;
           n=3; Coxiella burnetii|Rep: Sodium/calcium antiporter
           family protein - Coxiella burnetii
          Length = 322

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 23/78 (29%), Positives = 34/78 (43%)
 Frame = +2

Query: 185 YLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDI 364
           +L LAL  +  +  V         L +++ V            PE    ++G    E DI
Sbjct: 178 FLGLALLFISSELLVDGAVGAAQLLGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEHDI 237

Query: 365 GVGTIVGSAVFNILAVAA 418
            +G I+GS +FN LAV A
Sbjct: 238 AIGHIIGSNIFNSLAVLA 255



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 22/100 (22%), Positives = 44/100 (44%)
 Frame = +2

Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337
           ++L  ++ + +   L     + F+ A   +   L + + V            PEL V+ I
Sbjct: 3   VILKIIVELIVGAGLLAFGAERFITASAALARHLKIPSLVIGIILVGFGTSFPELIVSAI 62

Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457
             F  +  I +G +VGS   NI  +    G+ A +++P++
Sbjct: 63  AAFHGKTQISIGNVVGS---NIANIGLILGVVA-LIIPIE 98


>UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1;
           Pirellula sp.|Rep: Putative uncharacterized protein -
           Rhodopirellula baltica
          Length = 339

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 2/152 (1%)
 Frame = +2

Query: 137 LQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXP 316
           L R+   IV   ++      AL   CD  FV     +   L ++  V            P
Sbjct: 179 LGRRVAVIVWQLILLSAGVAALVFGCD-LFVDGAVSMARILGVSELVIGLTIVSAGTSLP 237

Query: 317 ELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGA--GMVVPLDWWPLTRDCLAY 490
           EL  +V  T   E  I +G  VGS   NI+AV     + A  G+ V  +   L    +  
Sbjct: 238 ELVTSVAATIKGERGIAIGNAVGSTTLNIVAVLGITSVIAPSGLNVADEILRLDMPLMVI 297

Query: 491 GITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586
              +S ++       V+W E  L++ +Y  Y+
Sbjct: 298 AAMLSWILYRTGRTIVRW-EGVLMIVIYCSYV 328


>UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:
           CG5685-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 950

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
 Frame = +2

Query: 314 PELFVNVIGTFITE---GDIGVGTIVGSAVFNILAVAACCGI 430
           PE+ ++VI  +  +   GD+G GTIVGSA +N+  + A C I
Sbjct: 193 PEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMI 234


>UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor
           (Na(+)/Ca(2+)-exchange protein 1); n=185;
           Euteleostomi|Rep: Sodium/calcium exchanger 1 precursor
           (Na(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human)
          Length = 973

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
 Frame = +2

Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424
           PE+ ++VI   G   T GD+G  TIVGSA FN+  + A C
Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186


>UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca
           exchanger; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Na/Ca exchanger -
           Strongylocentrotus purpuratus
          Length = 367

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
 Frame = +2

Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACCGIG 433
           PE+ ++VI   G     G +G  TIVGSA FN+L + A C +G
Sbjct: 105 PEILLSVIEIAGNGFQSGPLGPSTIVGSAAFNLLIITAVCIMG 147


>UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=9; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Silicibacter
           pomeroyi
          Length = 309

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD-CLAY 490
           PEL  +VI  +  + +I VG IVGS +FN+L +     + A + V   +        LA 
Sbjct: 215 PELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILGATAVIAPIPVASRFALFDLPVALAA 274

Query: 491 GITVSILI 514
            +T S+L+
Sbjct: 275 AVTFSVLL 282


>UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Desulfuromonas acetoxidans DSM
           684|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Desulfuromonas acetoxidans DSM 684
          Length = 314

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 27/94 (28%), Positives = 42/94 (44%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL  +++     E DI +G ++GS +FNIL V   C I   + V      L    +   
Sbjct: 219 PELAASLMSAAKGEMDISIGNVIGSNIFNILFVLGVCPIFQPIAVEPSILRLELPVVMLF 278

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595
               + +C       +W  A L+VS Y ++I  M
Sbjct: 279 SVALVPLCWHRHVIGRWKGAVLVVS-YVLFIVAM 311


>UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Firmicutes|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Clostridium
           perfringens (strain SM101 / Type A)
          Length = 331

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
           PEL V++        DI +G ++GS +FN+LA   C  I A +V+
Sbjct: 50  PELAVSISAALKGSNDITMGNVLGSNLFNLLAALGCTAIVAPLVI 94



 Score = 33.1 bits (72), Expect = 6.4
 Identities = 21/80 (26%), Positives = 36/80 (45%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           L+SI   + + ++  K  V +   I   L ++  +            PEL  +++     
Sbjct: 186 LLSIVGVIGI-ILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVAAKKG 244

Query: 353 EGDIGVGTIVGSAVFNILAV 412
           E DI +G I+GS  FNIL +
Sbjct: 245 ENDIALGNILGSNTFNILLI 264


>UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1;
           Moritella sp. PE36|Rep: Putative uncharacterized protein
           - Moritella sp. PE36
          Length = 340

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           AL+     L + ++  +  V    ++  A+ +++ +            PEL   + G   
Sbjct: 168 ALVETIAMLFMLLISSQIMVWGSVQLAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRR 227

Query: 350 TEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCLAYGITVSILI 514
              +I   T++GS  FN+L V A  G IG G+ +P +   LTRD     I  + ++
Sbjct: 228 GMPEIAFATVIGSNTFNLLGVLAFPGLIGDGLQLPAE--VLTRDLPMLSIMTAFMV 281



 Score = 36.7 bits (81), Expect = 0.52
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL V+ I +F     + VG  +GS + N   V A C +   +V+ + +       L + 
Sbjct: 54  PELVVSAIASFNGAEGLAVGNAIGSNIINCGLVLALCALFMPLVIKVRFIKRELPILVFA 113

Query: 494 ITVSILICIIHDEYVQWYE--AFLLVSLYGVYI 586
           +  +I + + +     W      LL++LY VY+
Sbjct: 114 LIATIAL-MSNGSITMWDSLILILLLALYCVYL 145


>UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1;
           Planctomyces maris DSM 8797|Rep: Sodium/calcium
           exchanger protein - Planctomyces maris DSM 8797
          Length = 368

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 17/42 (40%), Positives = 24/42 (57%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG 439
           PEL V+V GT   +GD+ VG  +GS + NI  +   C +  G
Sbjct: 74  PELMVSVTGTLAGKGDLAVGNALGSCLCNIGLIIGSCALLKG 115


>UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2;
           Bacteroidetes|Rep: Putative uncharacterized protein -
           Algoriphagus sp. PR1
          Length = 318

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 4/98 (4%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW-WPLTRDC-LA 487
           PEL  +V+ +     DI +G I+GS +FNI  +    G+ + ++ PLD+     +D  + 
Sbjct: 220 PELATSVVASLKKNNDIAIGNIIGSNIFNIFLI---LGV-SSIINPLDYQLSFNKDLYIL 275

Query: 488 YGITVSILICII--HDEYVQWYEAFLLVSLYGVYICIM 595
            G T+ + + +     + +  +EA +L+  Y VYI  +
Sbjct: 276 LGGTIFLFLAMFTGKRKSLDRWEAGILLLTYLVYIAYL 313


>UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=3; Gammaproteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM
           17024)
          Length = 331

 Score = 37.5 bits (83), Expect = 0.30
 Identities = 18/39 (46%), Positives = 24/39 (61%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
           PEL  +V+       DI +G I+GS +FN+LAV A  GI
Sbjct: 226 PELAASVMSALKGHHDIALGNIIGSNIFNLLAVMAVPGI 264


>UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep: Na+/Ca+
           antiporter, CaCA family - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 296

 Score = 37.5 bits (83), Expect = 0.30
 Identities = 18/43 (41%), Positives = 26/43 (60%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442
           PEL  ++I       DIGVG I+GS ++NIL +    G+GA +
Sbjct: 203 PELITSIIAIRKGHSDIGVGNIIGSNIYNILMI---MGVGAAL 242


>UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Prosthecochloris aestuarii DSM
           271|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Prosthecochloris aestuarii DSM 271
          Length = 334

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL 454
           PEL  +++G    E +I VG ++GS +FNIL V      G  M+ P+
Sbjct: 228 PELATSLVGAIRRESEISVGNLIGSNIFNILFVLG----GVSMIKPV 270


>UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: Na+/Ca+
           antiporter, CaCA family - Parvibaculum lavamentivorans
           DS-1
          Length = 350

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 26/94 (27%), Positives = 45/94 (47%)
 Frame = +2

Query: 242 KICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAAC 421
           +I  A  +++ V            PEL  +V+  F    D+ VG I+GS + NILA+   
Sbjct: 224 EIAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAI--- 280

Query: 422 CGIGAGMVVPLDWWPLTRDCLAYGITVSILICII 523
            G+ A ++ PL   P+  D L + + V +   ++
Sbjct: 281 LGVTA-LIAPL---PIDPDFLRFHLWVMLAAVVM 310


>UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Reinekea sp. MED297|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Reinekea sp. MED297
          Length = 321

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 23/87 (26%), Positives = 37/87 (42%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           AL+   + L + +V  +  V     I     ++  V            PEL  +V     
Sbjct: 171 ALVWFAIGLGVLIVSARVLVWGAVGIADMFQISEAVIGATIIAVGTSLPELAASVASALK 230

Query: 350 TEGDIGVGTIVGSAVFNILAVAACCGI 430
              DI +G ++GS +FNILAV +  G+
Sbjct: 231 KHHDIAIGNVLGSNIFNILAVLSVPGL 257


>UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger protein;
           n=1; marine gamma proteobacterium HTCC2080|Rep: Putative
           sodium/calcium exchanger protein - marine gamma
           proteobacterium HTCC2080
          Length = 321

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 36/156 (23%), Positives = 61/156 (39%), Gaps = 8/156 (5%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340
           +  A+ +  + L + +   K  V A   I  +  ++  V            PEL  +++ 
Sbjct: 164 IAQAIGAFTVGLGVLIGSSKALVWAAVNIAESYGVSELVIGLTIIALGTSLPELAASMVS 223

Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI 520
                 DI +G +VGS +FN+L V A  G+ + +   L    L RD     +T + L   
Sbjct: 224 AIKGHADIAIGAVVGSNMFNLLIVLAIPGLFSPL--ELSTTDLQRDLGTVFVTTAALAVF 281

Query: 521 I--------HDEYVQWYEAFLLVSLYGVYICIMYYD 604
           +            +      L +S Y VY   +YYD
Sbjct: 282 VGFGWRKEKSHARLGRMAGCLFLSSYVVYCLWLYYD 317


>UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like
           protein; n=1; Oikopleura dioica|Rep: Sodium/calcium
           exchanger protein-like protein - Oikopleura dioica
           (Tunicate)
          Length = 557

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 16/42 (38%), Positives = 28/42 (66%)
 Frame = +2

Query: 152 GAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277
           G  +L++L  ++LF+AL +V D +FVP + KI   L ++ +V
Sbjct: 73  GMNILYSLWCLWLFIALGLVADAFFVPNLTKISSQLKLSENV 114


>UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4;
           Halobacteriaceae|Rep: Na+/Ca2+-exchanging protein -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 344

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 22/67 (32%), Positives = 32/67 (47%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL   ++        +GVG IVGSA+FNIL V    GI     +      + ++   Y 
Sbjct: 62  PELLSVLVTALDGSFGLGVGAIVGSAIFNILVVPGLAGITTTQPLDATRTVVYKEAQFYM 121

Query: 494 ITVSILI 514
           + VS L+
Sbjct: 122 LAVSTLL 128


>UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6;
           Bacteria|Rep: Sodium/calcium exchanger - Shewanella
           oneidensis
          Length = 316

 Score = 36.7 bits (81), Expect = 0.52
 Identities = 16/39 (41%), Positives = 22/39 (56%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
           PEL  +V+     + DI +G IVGS +FNIL +     I
Sbjct: 215 PELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAI 253


>UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1;
           Algoriphagus sp. PR1|Rep: Sodium/calcium exchanger -
           Algoriphagus sp. PR1
          Length = 312

 Score = 36.7 bits (81), Expect = 0.52
 Identities = 35/150 (23%), Positives = 59/150 (39%), Gaps = 1/150 (0%)
 Frame = +2

Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367
           L L + +   K  V     I   L M+  +            PEL V+V        DI 
Sbjct: 9   LGLIILLYGGKILVDGASAIAVKLGMSAGLIGLTIVAFGTSAPELLVSVNAALKGNSDIS 68

Query: 368 VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWY 547
           VG ++GS + NI  V    G+   +++      L  D     +   +   + ++  ++ +
Sbjct: 69  VGNVIGSNIANIGMVLGISGLFYPILIRKS--TLRFDYFITVLVTLLFYAVSYNGMIELW 126

Query: 548 EAFLLVSLY-GVYICIMYYDKPIQNFAKGS 634
           E  LL SL+ G  + +  Y    Q  A+GS
Sbjct: 127 EGILLFSLFIGFNLYLFKYTD--QGLAEGS 154



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
 Frame = +2

Query: 173 LISIYLFLALAV---VCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGT 343
           L++I LFL   V   +  +  V    KI     ++  V            PEL  +++  
Sbjct: 169 LVAISLFLGGIVGLYIGSELLVNNAVKISREFGVSERVIGITIIAIGTSLPELITSIMAA 228

Query: 344 FITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL-AYGITVSILICI 520
              + D+ +G I+GS + N+L++     I   + V  ++  L  D L   G T+ +   I
Sbjct: 229 LSKKTDMAIGNILGSNIMNVLSILGITAIIKPIGVSDEF--LQSDFLWMIGFTLILFPLI 286

Query: 521 IHDEYVQWYEAFLLVSLYGVYI 586
                + + E  +L+  Y  Y+
Sbjct: 287 RTKMRISFIEGLILLIGYCTYL 308


>UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6); n=30;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 6
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) - Homo
           sapiens (Human)
          Length = 584

 Score = 36.7 bits (81), Expect = 0.52
 Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 1/145 (0%)
 Frame = +2

Query: 155 AIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNV 334
           A+ L+    +YLFL L V   K+F P +  I   L ++++V            P++F  +
Sbjct: 99  AVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSAL 158

Query: 335 IG-TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL 511
           +  +      + +G + G+ V     VA   GI           P  RD + Y + V + 
Sbjct: 159 VAFSDPHTAGLALGALFGAGVLVTTVVAG--GITILHPFMAASRPFFRDIVFYMVAVFLT 216

Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYI 586
             ++    V    A   + LY  Y+
Sbjct: 217 FLMLFRGRVTLAWALGYLGLYVFYV 241


>UniRef50_A4RX12 Cluster: CaCA family transporter: sodium
           ion/potassium ion/calcium ion; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: CaCA family transporter: sodium
           ion/potassium ion/calcium ion - Ostreococcus lucimarinus
           CCE9901
          Length = 569

 Score = 36.3 bits (80), Expect = 0.69
 Identities = 31/149 (20%), Positives = 62/149 (41%), Gaps = 6/149 (4%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           LI++    ALAV    +FVPA+E     + ++ +             P+L+  V  + ++
Sbjct: 140 LIAVASTYALAVAAGTFFVPALEYTATLMKISPEAAGVTLLALGNGAPDLYAQV--SELS 197

Query: 353 EG-----DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGI-TVSILI 514
           EG     ++ +G+ +GS  F    V       +   V ++   L      + +  +++L+
Sbjct: 198 EGVLPDLNVVIGSTLGSGFFIATVVLGVVIRASPNAVVINKDALGASMGLFAVANIALLL 257

Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMYY 601
            +    +  WY     VS Y  Y C + +
Sbjct: 258 AMCFGTFKMWYTMTFFVS-YATYFCFIAF 285


>UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a;
           n=7; Caenorhabditis|Rep: Na/ca exchangers protein 2,
           isoform a - Caenorhabditis elegans
          Length = 975

 Score = 36.3 bits (80), Expect = 0.69
 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 20/108 (18%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFV----------------PAVEKICHALNMTND-VXXXX 289
           VL+  +  Y+FL +++V D++                  P ++ +   + + ND V    
Sbjct: 60  VLYFFVIAYMFLGISIVADRFMSSIEVITSMERTIVVKRPGLDPMAVQVRIWNDTVSNLT 119

Query: 290 XXXXXXXXPELFVNVIGTF---ITEGDIGVGTIVGSAVFNILAVAACC 424
                   PE+ +++I         GD+G  TIVGSA FN+  + A C
Sbjct: 120 LMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAFNLFMIIAIC 167


>UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:
           ENSANGP00000016911 - Anopheles gambiae str. PEST
          Length = 563

 Score = 36.3 bits (80), Expect = 0.69
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +2

Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424
           + ++      GD+G GTIVGSA +N+  + A C
Sbjct: 147 IEIVAKNFNAGDLGPGTIVGSAAYNLFVIMAIC 179


>UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2
           precursor (Na(+)/Ca(2+)-exchange protein 2).; n=1;
           Takifugu rubripes|Rep: Sodium/calcium exchanger 2
           precursor (Na(+)/Ca(2+)-exchange protein 2). - Takifugu
           rubripes
          Length = 953

 Score = 35.9 bits (79), Expect = 0.91
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
 Frame = +2

Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424
           PE+ ++VI   G     G++G GTIVGSA FN+  +   C
Sbjct: 93  PEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLC 132


>UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=9; Bacteroidetes|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Flavobacteria
           bacterium BBFL7
          Length = 317

 Score = 35.9 bits (79), Expect = 0.91
 Identities = 27/135 (20%), Positives = 58/135 (42%), Gaps = 1/135 (0%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           +L  + + L L V+  ++ V +   +   L ++  +            PEL V++     
Sbjct: 2   SLFYLLIGLVLLVIGGEFLVRSSVGLSLKLRLSRMIIGLTVVSFATSAPELIVSIQSALD 61

Query: 350 TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD-CLAYGITVSILICIIH 526
               + +G ++GS + NI  V     + A + +  D++       +A+ I + IL+ +  
Sbjct: 62  GFSGLAIGNVIGSNIANIALVLGATALIAPLAIDKDFFKFNWPWMMAFSILLYILL-LSD 120

Query: 527 DEYVQWYEAFLLVSL 571
           +  V+W    LL S+
Sbjct: 121 NNLVRWEGGILLGSI 135



 Score = 33.5 bits (73), Expect = 4.8
 Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 8/147 (5%)
 Frame = +2

Query: 182 IYLFLALAVVC----DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           I++FLAL  +      +  V     I  +L +   +            PEL  ++I    
Sbjct: 167 IFMFLALGGLALWQGSELLVKGAVDIAASLGIPESIIAVSMVALGTSVPELAASIIAALK 226

Query: 350 TEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCL-AYGITVSIL-ICI 520
            E  I +G ++GS +FNI +V      I    + P     L  D     GI+ ++L +  
Sbjct: 227 KEKAISLGNLIGSNIFNIGSVLGITALIQPIQIQPEGMGLLNNDIFWMLGISFALLPLAF 286

Query: 521 IHDEY-VQWYEAFLLVSLYGVYICIMY 598
           +   Y +  Y+  L ++ Y ++I + +
Sbjct: 287 LPKVYHISRYKGILFLAAYLLFIYLAF 313


>UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Hyphomonas neptunium ATCC
           15444|Rep: K+-dependent Na+/Ca+ exchanger
           related-protein - Hyphomonas neptunium (strain ATCC
           15444)
          Length = 339

 Score = 35.9 bits (79), Expect = 0.91
 Identities = 13/33 (39%), Positives = 22/33 (66%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412
           PEL  +V+  F  + D+ +G ++GS +FNIL +
Sbjct: 220 PELATSVVAAFRKKADVALGNVIGSNLFNILGI 252


>UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; Psychrobacter|Rep: Na+/Ca+ antiporter, CaCA family
           precursor - Psychrobacter sp. PRwf-1
          Length = 322

 Score = 35.9 bits (79), Expect = 0.91
 Identities = 24/70 (34%), Positives = 37/70 (52%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL  +V      E D+ +G ++GS +FN L V     I   M   +D   L+RD +  G
Sbjct: 220 PELVASVAAARRGEHDMALGNVIGSNLFNTLGVVGLAAIIKPM-QHIDPQILSRDVMMVG 278

Query: 494 ITVSILICII 523
           + VS+L+ I+
Sbjct: 279 M-VSVLLFIL 287


>UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr6 scaffold_15, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 562

 Score = 35.9 bits (79), Expect = 0.91
 Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 2/148 (1%)
 Frame = +2

Query: 149 HGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFV 328
           + A++L  L+  YL   L      YF  ++E +   L ++ ++            P+LF 
Sbjct: 121 YSALILWLLVLFYL---LGNTAANYFCCSLEGLSRILKLSPNIAGVTLLSLGNGAPDLFA 177

Query: 329 NVIGTFITEGD-IGVGTIVGSAVFNILAVAACCGIGAGMVVP-LDWWPLTRDCLAYGITV 502
           +++     E + +G+ +I+G A F    V     I      P ++      D   + +++
Sbjct: 178 SIVSFMGDETEKVGLNSILGGAFFVSSIVVGIISISVCHSRPSIERSSFIWDVTFFLLSL 237

Query: 503 SILICIIHDEYVQWYEAFLLVSLYGVYI 586
           + L+ II    +  + A    SLY +Y+
Sbjct: 238 ACLLVIIMLGKINLWGAISFFSLYFIYV 265


>UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family
           transporter precursor; n=1; Thiomicrospira crunogena
           XCL-2|Rep: Ca2+:cation antiporter (CaCA) family
           transporter precursor - Thiomicrospira crunogena (strain
           XCL-2)
          Length = 329

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 4/148 (2%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           AL+ + L L + ++  K  V    +I    ++   +            PEL   +     
Sbjct: 179 ALVFLILGLVVLMISAKMMVWGAVEIAEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKK 238

Query: 350 TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAYGITVSILICIIH 526
            E D+ +G I+GS +FN+LAV +   + A  V+  D   L  D  +   +T+++L+  + 
Sbjct: 239 GEADLMIGNILGSNLFNLLAVMSMPALIAPSVI--DNATLLLDYPIMLALTLAMLLVALP 296

Query: 527 DE---YVQWYEAFLLVSLYGVYICIMYY 601
            +    +   E ++L+  +  Y+ ++Y+
Sbjct: 297 RKGKAVITKTEGYILLISFIGYMLLLYF 324


>UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;
           n=1; Plesiocystis pacifica SIR-1|Rep: K+-dependent
           Na+/Ca+ exchanger protein - Plesiocystis pacifica SIR-1
          Length = 325

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 27/89 (30%), Positives = 38/89 (42%)
 Frame = +2

Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367
           L LAL V   +  V     +   L ++  V            PEL V+       E DI 
Sbjct: 10  LGLALLVAGGEALVRGATSLAQLLRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIA 69

Query: 368 VGTIVGSAVFNILAVAACCGIGAGMVVPL 454
           +  ++GS +FNI   AA  G+ A +V PL
Sbjct: 70  LANVIGSNIFNI---AAIVGV-AALVAPL 94


>UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein
           precursor; n=5; Proteobacteria|Rep: Na+/Ca+ antiporter,
           CaCA family protein precursor - Psychromonas ingrahamii
           (strain 37)
          Length = 326

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 17/39 (43%), Positives = 22/39 (56%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
           PEL   +      E D+ VG I+GS +FNIL V A  G+
Sbjct: 223 PELAATIAAARKKEFDLAVGNIIGSNIFNILGVMALPGL 261


>UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3;
           Caenorhabditis|Rep: Sodium-calcium exchanger -
           Caenorhabditis elegans
          Length = 880

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
 Frame = +2

Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424
           PE+ ++VI   G     G++G  TIVGSA FN+  + A C
Sbjct: 143 PEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVC 182


>UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1;
           Methanosarcina mazei|Rep: Sodium-calcium exchanger
           protein - Methanosarcina mazei (Methanosarcina frisia)
          Length = 392

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 23/94 (24%), Positives = 44/94 (46%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PE   ++  +F     I +G ++GS + NI  + +   + +   V  +   L RD     
Sbjct: 53  PEFASSLTASFEQASGIVIGNVLGSNIANIGLIVSTAALLSN--VKTEELMLRRDGYIML 110

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595
            +V + +  + D  +  +EAF+ + LY VYI  +
Sbjct: 111 FSVFLFLLFVVDFRISRFEAFIFLLLYFVYILFL 144


>UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31;
           Coelomata|Rep: Sodium-calcium exchanger - Gallus gallus
           (Chicken)
          Length = 254

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +2

Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424
           + V G     GD+G  TIVGSA FN+  + A C
Sbjct: 55  IEVCGHGFVAGDLGPSTIVGSAAFNMFIIIAIC 87


>UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Sodium/calcium exchanger -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 329

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340
           V  A+  + L +A  +   +  +   E +   L + ++             PE+   +  
Sbjct: 171 VWRAIFYVPLGIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAA 230

Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGI-GAGMVVPL 454
            F   GD+  G I+GS VFNIL       + G   V PL
Sbjct: 231 AFRQRGDVVAGNILGSNVFNILGAGGIVALFGPFEVAPL 269


>UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Na+/Ca+
           antiporter, CaCA family precursor - Alkalilimnicola
           ehrlichei (strain MLHE-1)
          Length = 327

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 21/81 (25%), Positives = 36/81 (44%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           AL+ + L L + ++  +  V A   +     +   V            PEL   +     
Sbjct: 177 ALLWLLLGLVVLLISAQTAVWAATGLAERAGVAETVVGLTLVAVGTSLPELATCLAAARR 236

Query: 350 TEGDIGVGTIVGSAVFNILAV 412
           ++GDI +G I+GS +FN+L V
Sbjct: 237 SQGDIAIGNIIGSNIFNLLGV 257


>UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 737

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 11/106 (10%)
 Frame = +2

Query: 314 PELFVNVIGTFITEG----DIGVGTIVGSAVFNILAVAACCGIG-----AGMVVPLDWWP 466
           PE+ +++I   I  G     +G  TIVGSA FN+L +   C +         +  ++ + 
Sbjct: 111 PEILLSIIEITIMNGFEAGALGPSTIVGSAAFNLLCITGVCVMAVPKFETRRIKSMNVFA 170

Query: 467 LT--RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
           +T     LAY I + I++ +   + V+ +EA L    + + + I Y
Sbjct: 171 VTAITSLLAY-IWLFIILSVNTKDVVELWEAILTFLFFPILVIIAY 215


>UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum
           symbiosum|Rep: Ca2 /Na antiporter - Cenarchaeum
           symbiosum
          Length = 294

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
           PEL  +V+       DIGVG I+GS ++NIL +     + A + V
Sbjct: 201 PELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGVASMIAAVPV 245


>UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH0465
           protein - Bacillus halodurans
          Length = 318

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 20/91 (21%), Positives = 38/91 (41%)
 Frame = +2

Query: 176 ISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITE 355
           + + L  AL +    +FV     I   LN++  +            PE   ++I      
Sbjct: 4   VLLLLGFALLIKGADFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNGN 63

Query: 356 GDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
            D+ +G ++GS +FNI  V     + + ++V
Sbjct: 64  PDVALGNVIGSNMFNITLVVGLTALLSPLIV 94



 Score = 33.9 bits (74), Expect = 3.7
 Identities = 27/91 (29%), Positives = 40/91 (43%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL  ++      E +I +G IVGS++FNI  V         M V  D   +    L   
Sbjct: 223 PELVTSLTAALKKESEIALGNIVGSSIFNIFFVLGTAATITPMHV--DSRVVVDLLLLIF 280

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586
           +T+ +L+       V  YE  +L S Y  Y+
Sbjct: 281 LTLLLLVFSRTRYTVGKYEGLILASFYIGYM 311


>UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Chloroflexus|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Chloroflexus
           aurantiacus J-10-fl
          Length = 361

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PE+ V++   F  +G I +G IVGS + N++ +     +   +  P+D     RD L   
Sbjct: 50  PEIAVSLQAAFDGQGAITLGNIVGSNIANVMLILGVAAMFGSL--PVDQQIFRRD-LPIM 106

Query: 494 ITVSILICIIH-DEYVQWYEAFLLVSLYGVYICIMY 598
           I  S+L  ++  D  + W +  +++     Y  IM+
Sbjct: 107 IGASLLTFLLALDRTLSWVDGMIMLLALTGYGWIMW 142



 Score = 33.1 bits (72), Expect = 6.4
 Identities = 24/91 (26%), Positives = 38/91 (41%)
 Frame = +2

Query: 140 QRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPE 319
           QR   AIVL  L  +   L L ++  ++ V           ++  +            PE
Sbjct: 158 QRHWRAIVLQ-LAMVVGGLVLLILGARWLVDGAVTFASWFGVSELIIGLTIVAVGTSLPE 216

Query: 320 LFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412
           +  +VI     E DI VG ++GS + N+L V
Sbjct: 217 IATSVIAGLRGERDIAVGNVIGSNILNLLLV 247


>UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger
           antiporter; n=1; Psychroflexus torquis ATCC 700755|Rep:
           Probable sodium/calcium exchanger antiporter -
           Psychroflexus torquis ATCC 700755
          Length = 158

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIG----VGTIVGSAVFNILAVAACCGIGA-----GMVVPLDWWP 466
           PELF+ +   F  +  +G    +GT  GS +FN L + +   +G         V +    
Sbjct: 53  PELFIALFFLFFLKDVVGFSGGLGTSFGSVLFNSLIIPSAAVLGVLSKTNKKSVSVSRKI 112

Query: 467 LTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
           + RD         +LI  I    + W E+ +L+++Y +Y+  ++
Sbjct: 113 ILRDGFWLLFVEFMLIYFIQQGEISWIESSVLITIYVLYVMYLF 156


>UniRef50_A2Q2A6 Cluster: Zinc finger, RING-type; Transcription
           factor jumonji, jmjC; Zinc finger, C2H2-type; n=1;
           Medicago truncatula|Rep: Zinc finger, RING-type;
           Transcription factor jumonji, jmjC; Zinc finger,
           C2H2-type - Medicago truncatula (Barrel medic)
          Length = 1183

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 24/71 (33%), Positives = 33/71 (46%)
 Frame = +3

Query: 15  LPASRSIQRHFKI*TPPNEMAISGTALRLLSMTSLLDSSRSCNDSTELSYCTRSSPSIFF 194
           LP   +     K+  PP E+    T L  L+ TS+L    +CNDS ++S           
Sbjct: 575 LPDMTNCNDSKKVSCPPTELGGRDTGLLDLTTTSMLPEMTNCNDSKKVSCPPTELDGRDT 634

Query: 195 *LLQLFATNTL 227
            LL L AT+TL
Sbjct: 635 GLLDLTATSTL 645


>UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25;
           Enterobacteriaceae|Rep: Inner membrane protein yrbG -
           Escherichia coli (strain K12)
          Length = 325

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCLAY 490
           PEL   + G    E DI VG I+G+ +FNI+ V      I  G + PL +   +RD  + 
Sbjct: 223 PELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAY---SRD-YSV 278

Query: 491 GITVSI---LICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613
            + VSI   L+C             LL   + V++ ++Y+  PI
Sbjct: 279 MLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPI 322


>UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF10698,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 793

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
 Frame = +2

Query: 230 PAVEKICHALNMTND-VXXXXXXXXXXXXPELFVNVI---GTFITEGDIGVGTIVGSAVF 397
           P  EKI   + + N+ V            PE+ ++V+   G     G++G  TIVGSA F
Sbjct: 54  PGGEKISTRVRVWNETVSNLTLMALGSSAPEILLSVVEVCGHNFNAGELGPNTIVGSAAF 113

Query: 398 NILAVAACC 424
           N+  +   C
Sbjct: 114 NMFVIIGLC 122


>UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Eubacterium ventriosum ATCC 27560
          Length = 339

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 2/132 (1%)
 Frame = +2

Query: 197 ALAV-VCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373
           A+A+ V  +  V + + +  A  M+  +            PEL  + +     E D+ +G
Sbjct: 201 AIAIAVGGQVVVDSAKSLALAAGMSETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIG 260

Query: 374 TIVGSAVFNILAV-AACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYE 550
            +VGS + NIL V      I +  V  +++  +    ++   T+ + I       ++  E
Sbjct: 261 NVVGSNISNILLVLGLSAAISSVGVTAMNFVDI---IVSLAATIIVFIVASTQRTIKKKE 317

Query: 551 AFLLVSLYGVYI 586
              LV +Y  Y+
Sbjct: 318 GIFLVIIYAFYM 329



 Score = 33.1 bits (72), Expect = 6.4
 Identities = 24/96 (25%), Positives = 39/96 (40%)
 Frame = +2

Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340
           +L  ++ +  F+ L    D YFV     +   L + + V            PEL V+   
Sbjct: 4   ILDIILLLVGFVLLIKGAD-YFVDGSCAVAKRLRVPSIVIGLTIVAVGTSLPELAVSTFA 62

Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
                  I +G +VGS +FN+L V     +   M+V
Sbjct: 63  AVKHSNAIALGNVVGSNIFNLLMVIGITALFKDMLV 98


>UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13621,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 964

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +2

Query: 332 VIGTFITEGDIGVGTIVGSAVFNILAVAACC 424
           V G     G +G GTIVGSA FN+L +   C
Sbjct: 118 VCGHGFAAGALGPGTIVGSAAFNMLVIVGVC 148


>UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2;
           Bacteria|Rep: Na+/Ca2+-exchanging protein - Salinibacter
           ruber (strain DSM 13855)
          Length = 350

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = +2

Query: 314 PELFVNVIGTFIT-EGDIGVGTIVGSAVFNILAVAACCGIGA 436
           PEL   V+   +  + ++GV  +VGSA+FNIL + A  G+ A
Sbjct: 58  PELSTAVLSAALHGDFELGVAAVVGSALFNILMIPALAGLWA 99


>UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5;
           Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
           - Dinoroseobacter shibae DFL 12
          Length = 321

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412
           PEL   V+     + D+ +G ++GS +FNILA+
Sbjct: 222 PELATAVVAAIKRQSDVVLGNVIGSNIFNILAI 254


>UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3;
           Tetrahymena thermophila|Rep: Cation-exchanger protein 1
           - Tetrahymena thermophila
          Length = 594

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 36/180 (20%), Positives = 74/180 (41%), Gaps = 5/180 (2%)
 Frame = +2

Query: 83  RNCTPPAIDDFPAGLFTELQRQHGAI-VLHALISIYLFLALAVVCDKYFVPAVEKICHAL 259
           +NC    +  F    F ++++    + +L  LI +Y F  L+ + + Y  PA+ K+    
Sbjct: 26  QNCNVEQLVKFSYFYFCQVKQSIIVLDLLTILIPLYAFRMLSQISEYYLSPALAKVSKCF 85

Query: 260 NMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD---IGVGTIVGSAVFNILAVAACCGI 430
            ++  V            P++   ++    + GD   I VG+I G+ +F           
Sbjct: 86  KLSQSVAGVTLLALGNGGPDVATAIVAG-SSGGDSITIAVGSIFGAGLFVTTYTLQNVIQ 144

Query: 431 GAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYI-CIMYYDK 607
            AG  + +      RD + Y I   ++        +    A   +S+YG+++  ++Y D+
Sbjct: 145 NAGS-IHIKSKTFVRDMVFYLIGCCVVFIYTIVGSINLGMAIGFMSIYGLFLFTVIYQDR 203


>UniRef50_Q6CTM9 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome C of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=2; Saccharomycetaceae|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome C of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 380

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 20/83 (24%), Positives = 39/83 (46%)
 Frame = -3

Query: 265 HVKRMTNFFNSRYKVFVANNCKS*KKIDGDERVQYDSSVLSLQLREESSREVIDSRRSAV 86
           H + +   FNS+    + N       ID D+++ ++  V+ +++  +   + IDS    +
Sbjct: 28  HDQVLPILFNSKLDTSILNKIWFLADIDDDDQLDFEEFVICMRMIFDMVNKNIDSVPDEL 87

Query: 85  PDIAISFGGVHILKWRCMERDAG 17
           PD  I      ++K R  ER +G
Sbjct: 88  PDWLIPGSKAELVKQRKTERSSG 110


>UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2;
           Methanosarcina|Rep: Sodium/calcium exchanger protein -
           Methanosarcina acetivorans
          Length = 418

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 22/100 (22%), Positives = 39/100 (39%)
 Frame = +2

Query: 131 TELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXX 310
           +E++    + +L  LI + +     VV  KYF+         L +   +           
Sbjct: 261 SEIKNPSESSLLKELIKLIVSGIAIVVGAKYFIEQSIFFALLLEIPETLIGISLVAIGTS 320

Query: 311 XPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
            PEL V +         I +G ++GS + N L +  C G+
Sbjct: 321 LPELMVTISAARSGYASIALGNVIGSNITNTLLILGCSGL 360


>UniRef50_P13983 Cluster: Extensin precursor; n=1; Nicotiana
           tabacum|Rep: Extensin precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 620

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
 Frame = -2

Query: 494 SHKPDNL**EATSPKEQPFPHQYHNKPPQLIY*RQPNPLWS--PLRYHPP 351
           +H+P  L     SP+ QP P  Y   PP      QP+P +S  P  Y PP
Sbjct: 243 THQPSPLRHLPPSPRRQPQPPTYSPPPPAYAQSPQPSPTYSPPPPTYSPP 292


>UniRef50_UPI00006CC43D Cluster: Major Facilitator Superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep: Major
           Facilitator Superfamily protein - Tetrahymena
           thermophila SB210
          Length = 586

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 18/73 (24%), Positives = 30/73 (41%)
 Frame = +2

Query: 380 VGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFL 559
           +GS +F  + VA  CG+  GM            C    +  S+ I ++    V W    +
Sbjct: 63  LGSGIFPFMMVAVACGVPVGMKAIKYVGSARLVCYVCSLIASLCILLVSYAKVFWLFVII 122

Query: 560 LVSLYGVYICIMY 598
              ++G +  IMY
Sbjct: 123 YGIIFGFFTGIMY 135


>UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1
           precursor (Na(+)/Ca(2+)-exchange protein 1).; n=1;
           Takifugu rubripes|Rep: Sodium/calcium exchanger 1
           precursor (Na(+)/Ca(2+)-exchange protein 1). - Takifugu
           rubripes
          Length = 900

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
 Frame = +2

Query: 230 PAVEKICHALNMTND-VXXXXXXXXXXXXPELFVNVI---GTFITEGDIGVGTIVGSAVF 397
           P  EKI   + + N+ V            PE+ ++V+   G     G++G  TIVGSA F
Sbjct: 105 PNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAF 164

Query: 398 NILAVAACC 424
           N+  +   C
Sbjct: 165 NMFVIIGLC 173


>UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14779,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 880

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
 Frame = +2

Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424
           PE+ ++VI   G     G +G  TIVGSA FN+  + A C
Sbjct: 90  PEILLSVIEVCGHNFESGALGPSTIVGSAAFNMFVIIAIC 129


>UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=17; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Silicibacter
           pomeroyi
          Length = 319

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412
           PEL   V+     + D+ +G ++GS +FN+LA+
Sbjct: 225 PELATTVMAALRRQADVALGNVIGSNMFNLLAI 257


>UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
           n=3; Epsilonproteobacteria|Rep: Calcium:H+/Na+
           antiporter, CaCA family - Nitratiruptor sp. (strain
           SB155-2)
          Length = 308

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 29/138 (21%), Positives = 54/138 (39%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352
           LI + +   + V    + V +   I  +L ++  +            PEL V+++     
Sbjct: 168 LILLLVGFVMVVYGADFAVESASHIARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMND 227

Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDE 532
           + D+ +G I+GS V N   V     +   + V +  +    D L   I   +LI I    
Sbjct: 228 KADMSIGNIIGSNVANFSVVLGSAALVNPLHVNMHTYAF--DILTAIIASVMLIFITATR 285

Query: 533 YVQWYEAFLLVSLYGVYI 586
                   +L++  GV+I
Sbjct: 286 LYNKSAGIVLLATLGVFI 303


>UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 320

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 22/81 (27%), Positives = 37/81 (45%)
 Frame = +2

Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349
           A + + + LAL +   +  V    +I   L +++ V            PEL  +V     
Sbjct: 168 ATLWLLVGLALLMGSSRGVVWGASEIASTLGVSDLVIGLTVVAIGTSLPELAASVASALR 227

Query: 350 TEGDIGVGTIVGSAVFNILAV 412
            E  + +G ++GS VFN+LAV
Sbjct: 228 GEDAMAIGNVLGSNVFNLLAV 248


>UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Marinobacter sp. ELB17|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Marinobacter sp. ELB17
          Length = 328

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448
           PEL  +V      + D+ +G IVGS +FNIL+V A   +   +V+
Sbjct: 222 PELTASVAAARKGQSDMIIGGIVGSNIFNILSVMAITAVVKPLVI 266


>UniRef50_Q5ZC54 Cluster: Putative uncharacterized protein
           P0443D08.40; n=1; Oryza sativa (japonica
           cultivar-group)|Rep: Putative uncharacterized protein
           P0443D08.40 - Oryza sativa subsp. japonica (Rice)
          Length = 335

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 455 DWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFL-LVSLYGVYICIMYYDKPIQNFAKG 631
           D W   R+  AYGI V I++    D  VQ+Y  +L  + LYG      Y+ +P    + G
Sbjct: 63  DLWDGFRESSAYGIAVPIVLNGCSDGVVQYYVPYLSAIQLYGRLRRHFYHSRPSGEDSDG 122

Query: 632 SW 637
            +
Sbjct: 123 DY 124


>UniRef50_A2WKF8 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. indica (Rice)
          Length = 286

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 455 DWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFL-LVSLYGVYICIMYYDKPIQNFAKG 631
           D W   R+  AYGI V I++    D  VQ+Y  +L  + LYG      Y+ +P    + G
Sbjct: 63  DLWDGFRESSAYGIAVPIVLNGCSDGVVQYYVPYLSAIQLYGRLRRHFYHSRPSGEDSDG 122

Query: 632 SW 637
            +
Sbjct: 123 DY 124


>UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_89,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 553

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 2/138 (1%)
 Frame = +2

Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD-- 361
           +F  L+   + Y  PAV  I     ++  +            P++   +I T   +    
Sbjct: 66  MFNLLSKTAENYLSPAVAHIAKYFKLSQTLSGITLIALANGAPDVITAIIATGEDDQGVL 125

Query: 362 IGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 541
           I VG+I GS +F    V       +  ++ ++   LTRD +   + +  +I   +  Y+ 
Sbjct: 126 IAVGSIFGSGLFMTTFVLGSVLYYSKHIL-VNKVSLTRDLIFNILGIGSIITFGYIGYIS 184

Query: 542 WYEAFLLVSLYGVYICIM 595
              + L VSLY +YI ++
Sbjct: 185 NQFSILFVSLYIMYIFVV 202


>UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome
           shotgun sequence; n=10; Clupeocephala|Rep: Chromosome 10
           SCAF15123, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1007

 Score = 33.1 bits (72), Expect = 6.4
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
 Frame = +2

Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424
           PE+ ++VI   G     G++G  TIVGSA FN+  +   C
Sbjct: 110 PEILLSVIEVCGHDFKPGELGPATIVGSAAFNMFVIIGLC 149


>UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Parvularcula bermudensis
           HTCC2503|Rep: K+-dependent Na+/Ca+ exchanger
           related-protein - Parvularcula bermudensis HTCC2503
          Length = 327

 Score = 33.1 bits (72), Expect = 6.4
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430
           PEL   +      E  + VG ++GS +FNIL V    G+
Sbjct: 223 PELATVIAAARKAEASVAVGNVIGSNIFNILFVGGAMGV 261


>UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative,
           expressed; n=6; Magnoliophyta|Rep: Magnesium/proton
           exchanger, putative, expressed - Oryza sativa subsp.
           japonica (Rice)
          Length = 523

 Score = 33.1 bits (72), Expect = 6.4
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 7/91 (7%)
 Frame = +2

Query: 347 ITEGDIGVGTIVGSAVFNILAVAACCGI--GAG---MVVPLDWW--PLTRDCLAYGITVS 505
           +T G +G GT+VGSA F++  + A C +   AG    +  L  W   L     AY I + 
Sbjct: 117 LTAGGLGPGTLVGSAAFDLFPIHAVCVVMPRAGSKKKISDLGVWLVELFWSFWAY-IWLY 175

Query: 506 ILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598
           I++ +     +  +EA L V  YG+ +   Y
Sbjct: 176 IILEVWTPRVITLWEALLTVLQYGLLLLHAY 206


>UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor
           (Na(+)/Ca(2+)-exchange protein 3); n=109; Eumetazoa|Rep:
           Sodium/calcium exchanger 3 precursor
           (Na(+)/Ca(2+)-exchange protein 3) - Homo sapiens (Human)
          Length = 927

 Score = 33.1 bits (72), Expect = 6.4
 Identities = 14/33 (42%), Positives = 18/33 (54%)
 Frame = +2

Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424
           + V G     GD+G  TIVGSA FN+  +   C
Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185


>UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1;
           Aquifex aeolicus|Rep: Putative uncharacterized protein -
           Aquifex aeolicus
          Length = 322

 Score = 32.7 bits (71), Expect = 8.4
 Identities = 17/69 (24%), Positives = 28/69 (40%)
 Frame = +2

Query: 245 ICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424
           +  AL ++  V            PELF + +  +    DI +G + GS +FN   V    
Sbjct: 199 LAKALGVSEAVIGLFVVAIGTSLPELFASAVSAYKGNPDIALGNVAGSNIFNATLVLGTS 258

Query: 425 GIGAGMVVP 451
            +   + VP
Sbjct: 259 SVIRDIPVP 267


>UniRef50_Q1ARL7 Cluster: Sodium/calcium exchanger membrane region
           precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
           Sodium/calcium exchanger membrane region precursor -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 338

 Score = 32.7 bits (71), Expect = 8.4
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 9/97 (9%)
 Frame = +2

Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI---GT 343
           ++ + L L   ++    F  AVE +   LNM                PE  + ++   G 
Sbjct: 3   IVELILSLGAILLAAFLFTNAVEILGERLNMGQGAVGSVLAAVGTALPETMIPIVAILGA 62

Query: 344 FI------TEGDIGVGTIVGSAVFNILAVAACCGIGA 436
            I      T G+IGVG I+G+    +LA  A C IGA
Sbjct: 63  LILGRDPQTAGEIGVGAILGAPF--LLATLAMCVIGA 97


>UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Na+/Ca+
           antiporter, CaCA family - Alkaliphilus metalliredigens
           QYMF
          Length = 334

 Score = 32.7 bits (71), Expect = 8.4
 Identities = 21/93 (22%), Positives = 44/93 (47%)
 Frame = +2

Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493
           PEL V+VI T     D+ +G ++GS + N+  +     + + + +    + + R     G
Sbjct: 54  PELLVSVIATQQHYYDVAIGNVIGSMICNVGLILGLTTLFSPIKLNRSGFAI-RGFFMLG 112

Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICI 592
            T ++++  + D  +   E    + L+ +YI I
Sbjct: 113 ST-ALMLFFLRDRMISPREGTWFIVLFTIYILI 144


>UniRef50_Q8ILY2 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 551

 Score = 32.7 bits (71), Expect = 8.4
 Identities = 18/64 (28%), Positives = 31/64 (48%)
 Frame = -3

Query: 400 IEDSRTHYGPHSDITLRNEGTYDVHE*FWCRSSCGHESRSSHIVCHVKRMTNFFNSRYKV 221
           I +S+++Y P   I+  N    D H  +       H SRS+ +    K + N FN++ ++
Sbjct: 376 INNSQSNYIPSIHISSLNCNEIDPHNKYISTKGAIHNSRSNLLTNQTKNIQNDFNNKTQM 435

Query: 220 FVAN 209
           F  N
Sbjct: 436 FKEN 439


>UniRef50_A0BCS6 Cluster: Chromosome undetermined scaffold_10, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_10,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 582

 Score = 32.7 bits (71), Expect = 8.4
 Identities = 14/29 (48%), Positives = 17/29 (58%)
 Frame = -2

Query: 437 PHQYHNKPPQLIY*RQPNPLWSPLRYHPP 351
           P Q   +PPQ+IY + P PL  P  Y PP
Sbjct: 155 PQQPIIQPPQIIYQQMPQPLQQPQYYPPP 183


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 695,795,657
Number of Sequences: 1657284
Number of extensions: 13975643
Number of successful extensions: 39015
Number of sequences better than 10.0: 200
Number of HSP's better than 10.0 without gapping: 37350
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38959
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52479343733
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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