BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= brS-0304 (678 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.... 300 2e-80 UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogast... 298 9e-80 UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-... 226 4e-58 UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute car... 217 3e-55 UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-... 208 1e-52 UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exch... 204 2e-51 UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exch... 201 1e-50 UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella ve... 198 1e-49 UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 pr... 196 4e-49 UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:1... 188 1e-46 UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exch... 180 3e-44 UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute car... 178 1e-43 UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-... 173 2e-42 UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchang... 173 3e-42 UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome sh... 172 6e-42 UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/pot... 169 5e-41 UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 pr... 168 9e-41 UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exch... 167 3e-40 UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium excha... 165 7e-40 UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella ve... 163 3e-39 UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx... 163 4e-39 UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exch... 162 6e-39 UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; ... 161 2e-38 UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 pr... 160 3e-38 UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exch... 159 4e-38 UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve... 159 8e-38 UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchang... 156 5e-37 UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 pr... 156 5e-37 UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potass... 154 2e-36 UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:... 153 5e-36 UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - M... 151 2e-35 UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome s... 150 4e-35 UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleosto... 149 5e-35 UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus nor... 149 5e-35 UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (N... 149 5e-35 UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchang... 149 8e-35 UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N... 148 1e-34 UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Eut... 147 2e-34 UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|... 147 2e-34 UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella ve... 143 3e-33 UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;... 142 7e-33 UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella ve... 136 5e-31 UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amure... 135 1e-30 UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchang... 133 3e-30 UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calci... 128 1e-28 UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchang... 124 2e-27 UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n... 124 2e-27 UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogas... 122 6e-27 UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isof... 116 4e-25 UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodiu... 113 4e-24 UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gamb... 113 5e-24 UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc... 100 4e-20 UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaste... 98 2e-19 UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061... 97 3e-19 UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis ... 82 1e-14 UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/cal... 65 1e-09 UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger... 64 2e-09 UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependen... 62 2e-08 UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-... 58 1e-07 UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus ... 55 1e-06 UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, who... 54 4e-06 UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antip... 51 2e-05 UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05 UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus... 48 3e-04 UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole gen... 48 3e-04 UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenor... 48 3e-04 UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr... 47 4e-04 UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-... 47 4e-04 UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella ve... 47 5e-04 UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 46 6e-04 UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related ... 46 6e-04 UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis th... 46 6e-04 UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; A... 46 8e-04 UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|... 46 8e-04 UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep... 46 0.001 UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-... 46 0.001 UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-... 45 0.001 UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneum... 45 0.002 UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobac... 45 0.002 UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-... 44 0.003 UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;... 44 0.003 UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: ... 44 0.005 UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-... 44 0.005 UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane regio... 43 0.008 UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 pre... 43 0.008 UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; T... 42 0.010 UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; ... 42 0.010 UniRef50_UPI00006CE59A Cluster: probable Mg2+-specific channel-l... 42 0.014 UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 42 0.014 UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-... 42 0.014 UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Ar... 42 0.014 UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; H... 42 0.014 UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 42 0.018 UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; R... 42 0.018 UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091... 42 0.018 UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; ... 41 0.024 UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 41 0.024 UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; ... 41 0.024 UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:... 41 0.024 UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteob... 41 0.032 UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 41 0.032 UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger prote... 40 0.042 UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; ... 40 0.042 UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteob... 40 0.056 UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 40 0.056 UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; F... 40 0.056 UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;... 40 0.056 UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomon... 40 0.056 UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriacea... 40 0.056 UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; ... 40 0.056 UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;... 40 0.074 UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; ... 40 0.074 UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein... 40 0.074 UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 40 0.074 UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na... 40 0.074 UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloa... 40 0.074 UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamm... 39 0.097 UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillat... 39 0.097 UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Re... 39 0.097 UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-... 39 0.13 UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like pro... 39 0.13 UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisph... 39 0.13 UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 39 0.13 UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|... 39 0.13 UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; M... 39 0.13 UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protei... 38 0.17 UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17 UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:... 38 0.17 UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (N... 38 0.17 UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca exch... 38 0.22 UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-... 38 0.22 UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-... 38 0.22 UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-... 38 0.22 UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22 UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; ... 38 0.22 UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; ... 38 0.22 UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-... 38 0.30 UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; C... 38 0.30 UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-... 37 0.39 UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P... 37 0.39 UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-... 37 0.39 UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger prote... 37 0.39 UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like p... 37 0.39 UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halob... 37 0.39 UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria... 37 0.52 UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriph... 37 0.52 UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 pr... 37 0.52 UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/pot... 36 0.69 UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; ... 36 0.69 UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:... 36 0.69 UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precu... 36 0.91 UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 36 0.91 UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-... 36 0.91 UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 36 0.91 UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole geno... 36 0.91 UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family tr... 36 1.2 UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;... 36 1.2 UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein... 36 1.2 UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorha... 36 1.2 UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; ... 36 1.2 UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31; Coeloma... 35 1.6 UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomon... 35 1.6 UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 35 1.6 UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.6 UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum sy... 35 1.6 UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH04... 35 2.1 UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 35 2.1 UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antip... 35 2.1 UniRef50_A2Q2A6 Cluster: Zinc finger, RING-type; Transcription f... 35 2.1 UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Ente... 35 2.1 UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whol... 34 2.8 UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; ... 34 2.8 UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whol... 34 3.7 UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacte... 34 3.7 UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; A... 34 3.7 UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3; Tetrah... 34 3.7 UniRef50_Q6CTM9 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 34 3.7 UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; ... 34 3.7 UniRef50_P13983 Cluster: Extensin precursor; n=1; Nicotiana taba... 34 3.7 UniRef50_UPI00006CC43D Cluster: Major Facilitator Superfamily pr... 33 4.8 UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precu... 33 4.8 UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whol... 33 4.8 UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-... 33 4.8 UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;... 33 4.8 UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; ... 33 4.8 UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-... 33 4.8 UniRef50_Q5ZC54 Cluster: Putative uncharacterized protein P0443D... 33 4.8 UniRef50_A2WKF8 Cluster: Putative uncharacterized protein; n=2; ... 33 4.8 UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, wh... 33 4.8 UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome s... 33 6.4 UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 33 6.4 UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, e... 33 6.4 UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (N... 33 6.4 UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; ... 33 8.4 UniRef50_Q1ARL7 Cluster: Sodium/calcium exchanger membrane regio... 33 8.4 UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; A... 33 8.4 UniRef50_Q8ILY2 Cluster: Putative uncharacterized protein; n=1; ... 33 8.4 UniRef50_A0BCS6 Cluster: Chromosome undetermined scaffold_10, wh... 33 8.4 >UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.3; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG2893-PB.3 - Tribolium castaneum Length = 480 Score = 300 bits (736), Expect = 2e-80 Identities = 141/189 (74%), Positives = 156/189 (82%), Gaps = 4/189 (2%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCTPPAIDDFP FTE +RQ GA+V+H ++S+YLF+ALAVVCDK+FVPAVEKICHALNM Sbjct: 4 NCTPPAIDDFPRDFFTEKERQDGAVVVHVVVSLYLFVALAVVCDKFFVPAVEKICHALNM 63 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM- 442 + DV PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG+ Sbjct: 64 SADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGLC 123 Query: 443 ---VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613 VVPLDWWPLTRDCLAYGITVSILICIIHDE V+WYEA LV LY VYI IMY+DK I Sbjct: 124 GVKVVPLDWWPLTRDCLAYGITVSILICIIHDERVEWYEALTLVLLYTVYILIMYFDKSI 183 Query: 614 QNFAKGSWE 640 Q A+G ++ Sbjct: 184 QRCARGGFK 192 >UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogaster|Rep: CG2893-PC.3 - Drosophila melanogaster (Fruit fly) Length = 542 Score = 298 bits (731), Expect = 9e-80 Identities = 134/182 (73%), Positives = 152/182 (83%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCT PAIDDFP LF+E QRQ GA+VLH + S+YLF+ALAVVCD+YFVPAVEKIC ALNM Sbjct: 21 NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNM 80 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 +NDV PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM Sbjct: 81 SNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMT 140 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625 +PLDWWPLTRD +AYG+TV+ILIC++HDE V+WYEA +LVSLY VY+ +MY+DK Q A Sbjct: 141 IPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCA 200 Query: 626 KG 631 KG Sbjct: 201 KG 202 >UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative - Nasonia vitripennis Length = 561 Score = 226 bits (552), Expect = 4e-58 Identities = 98/176 (55%), Positives = 127/176 (72%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCTPP+I +FP+ T QRQHG IV+H +I+ Y F LA+VCD +FVP++ KIC + M Sbjct: 95 NCTPPSIKEFPSDGLTRYQRQHGFIVIHVIIACYAFFLLAIVCDDFFVPSIVKICDKIGM 154 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 + DV PELF+N++GTF+TEGD+GVGTIVGSAVFNILAV ACCG+ A V Sbjct: 155 SKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNILAVPACCGLFASQV 214 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613 + LDWWP++RD LAYG+TV +LI +HD ++WYEAF+LV Y YI M ++K I Sbjct: 215 LDLDWWPISRDSLAYGVTVLLLIFTLHDGRIEWYEAFILVLFYIFYILAMVFNKRI 270 >UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute carrier family 24, member 5; n=1; Apis mellifera|Rep: PREDICTED: similar to solute carrier family 24, member 5 - Apis mellifera Length = 439 Score = 217 bits (529), Expect = 3e-55 Identities = 96/179 (53%), Positives = 130/179 (72%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCTPPAI +FP+ T QRQ G I++H +I+IY+FL LA+VCD +FVP+++KIC +N+ Sbjct: 23 NCTPPAIKEFPSDGLTREQRQLGFILIHFVIAIYMFLLLAIVCDDFFVPSIKKICDKINV 82 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 + DV PELF+N++GTFITEGD+GVGTIVGSAVFNILAV ACCG+ A + Sbjct: 83 SEDVAGATIMATATSSPELFINIVGTFITEGDLGVGTIVGSAVFNILAVPACCGLFANQI 142 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 + L+ WP+TRD +AY ITV +LI + D ++WYEA +LV Y +YI +M +D+ I F Sbjct: 143 LNLEAWPVTRDTIAYAITVFLLILTLRDGRIEWYEALILVLSYFLYILVMCFDRNIHQF 201 >UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-dependent Na/Ca exchanger NCKX3; n=2; Deuterostomia|Rep: PREDICTED: similar to potassium-dependent Na/Ca exchanger NCKX3 - Strongylocentrotus purpuratus Length = 570 Score = 208 bits (507), Expect = 1e-52 Identities = 91/173 (52%), Positives = 119/173 (68%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCTP I++FP LFTE QR GA + HA+ ++Y+F+ALA+VCD YFV ++EKIC L++ Sbjct: 75 NCTPSTIEEFPGDLFTEEQRAKGAFITHAICAVYMFIALAIVCDDYFVSSLEKICENLSL 134 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 T DV PELF +VIG FI +GD+GVGTIVGSAVFNIL + CG+ AG V Sbjct: 135 TEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGLCGLFAGQV 194 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604 V L WWPL RD L Y I+V L+ +I D Y+ WYEA +++ +Y Y+ IM +D Sbjct: 195 VHLSWWPLFRDTLVYAISVVTLVLVIRDGYINWYEALVMLLMYLCYVIIMCFD 247 >UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=1; Aedes aegypti|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 492 Score = 204 bits (497), Expect = 2e-51 Identities = 95/122 (77%), Positives = 101/122 (82%) Frame = +2 Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 M+NDV PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM Sbjct: 1 MSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60 Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 VVPLDWWPLTRDCLAYGITV+ILICIIHDE V+WYEA +LV LY VYI +MYYDK Q Sbjct: 61 VVPLDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYIAVMYYDKAFQKC 120 Query: 623 AK 628 A+ Sbjct: 121 AR 122 >UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=3; Endopterygota|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 542 Score = 201 bits (491), Expect = 1e-50 Identities = 94/180 (52%), Positives = 119/180 (66%) Frame = +2 Query: 83 RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262 RNCTP AI +FP+ FT +R+HG I +H LI+ Y F LA+VCD YFVPA+E +C L Sbjct: 95 RNCTPAAIFEFPSDGFTREERKHGWITVHLLIACYCFWLLAIVCDDYFVPAIELMCKKLQ 154 Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 + D+ PELF+N +GTFIT+GDIGVG +VGSAVFNILAV A CG+ G Sbjct: 155 VKEDIAGATFMAAASSSPELFINCVGTFITKGDIGVGAVVGSAVFNILAVPAVCGLFGGQ 214 Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 VV L WWP+TRD + YG+ V LI +++D V WYEA +LVS Y +YI M + I F Sbjct: 215 VVQLRWWPVTRDSMMYGMAVIGLITVLNDGKVMWYEATILVSAYVLYITAMICNDSINRF 274 >UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 490 Score = 198 bits (482), Expect = 1e-49 Identities = 91/179 (50%), Positives = 121/179 (67%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCTPPAI +FP FT+ QRQ GA+VL+ +IS+Y+F A+A+VCD YFVP +E IC L + Sbjct: 1 NCTPPAILEFPDDFFTQRQRQRGAVVLNFIISLYMFWAVAIVCDDYFVPCLEIICDRLGL 60 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 DV PELF +VIG FIT+GDIGVGTI+GSAVFN+L V CG+GAG V Sbjct: 61 QTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTV 120 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 + L WWP+ RD + Y ++ L+ ++ D V W EA +VS Y VY+ IMY++ I+ + Sbjct: 121 LYLAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLLIMYFNPRIEAY 179 >UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3); n=55; Eumetazoa|Rep: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) - Homo sapiens (Human) Length = 644 Score = 196 bits (478), Expect = 4e-49 Identities = 90/174 (51%), Positives = 120/174 (68%) Frame = +2 Query: 83 RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262 +NCT PA+ +FP +FT R+ GA+VLH L +IY+F ALA+VCD +FVP++EKIC L+ Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144 Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 ++ DV PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204 Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604 VV L W L RD + Y ++V LI I+DE V W+E+ +LV +Y +YI IM Y+ Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYN 258 >UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:112072 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 569 Score = 188 bits (457), Expect = 1e-46 Identities = 88/183 (48%), Positives = 120/183 (65%) Frame = +2 Query: 83 RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262 +NCT PAI +FP LFT QR GA++LH ++Y+FLALA+VCD YFV ++EKIC L+ Sbjct: 59 KNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDDYFVTSLEKICEKLH 118 Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 ++ DV PELF ++IG FIT GD+GVGTIVGSAVFNIL + CGI AG Sbjct: 119 LSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQ 178 Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 VV L + + RD Y I+V LI I+D+ + W+E+ +L+ +Y YI +M ++ +QN Sbjct: 179 VVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLGYIIVMKFNTSLQNL 238 Query: 623 AKG 631 G Sbjct: 239 FNG 241 >UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exchanger 5; n=1; Apis mellifera|Rep: PREDICTED: similar to Na-Ca exchanger 5 - Apis mellifera Length = 489 Score = 180 bits (438), Expect = 3e-44 Identities = 82/178 (46%), Positives = 115/178 (64%) Frame = +2 Query: 83 RNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALN 262 + CT +I DFP LFT QR+HGA++LHA + +Y FL A VC Y +PAV++IC +LN Sbjct: 24 KKCTDRSIHDFPEDLFTYEQRRHGAVILHAFLGLYCFLLTAFVCHDYLLPAVDRICISLN 83 Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 ++ DV PELFVNVIGTF+TE D+G GT+VGSAVF+ A AC + Sbjct: 84 ISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFDTFATPACGALMTFY 143 Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 616 + L+W L+RDCL Y I+V L+ I+ D +QWYEA +L+ L+ Y+ +++ K I+ Sbjct: 144 AISLEWQVLSRDCLMYVISVGTLVIIMWDAKIQWYEAMILLILFCFYLILLFCGKHIR 201 >UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute carrier family 24, member 5; n=1; Tribolium castaneum|Rep: PREDICTED: similar to solute carrier family 24, member 5 - Tribolium castaneum Length = 488 Score = 178 bits (433), Expect = 1e-43 Identities = 80/172 (46%), Positives = 113/172 (65%) Frame = +2 Query: 107 DDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXX 286 +DFP+ +FTE Q + G I+L I IY F LA++CD YF+P VEKIC ALN+++DV Sbjct: 50 EDFPS-MFTETQVEKGGIILVFCIGIYCFTLLAIICDNYFLPCVEKICEALNLSHDVAAA 108 Query: 287 XXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP 466 PELFVN+IGTFITE DIG+GT+VGS++FN L VA+ + A V L WWP Sbjct: 109 TFMSVATSTPELFVNIIGTFITESDIGIGTVVGSSLFNTLGVASLGSLAASTPVQLHWWP 168 Query: 467 LTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 ++RD + Y +++ +L+ I D Y+ WYE +L +Y +Y +M+ + I NF Sbjct: 169 ISRDVIIYILSILLLVGITWDGYIYWYEGLVLFLVYFIYFTVMFQNVRISNF 220 >UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative - Nasonia vitripennis Length = 692 Score = 173 bits (422), Expect = 2e-42 Identities = 79/198 (39%), Positives = 120/198 (60%) Frame = +2 Query: 35 TTPLQNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVC 214 TTP + + + R NC+PPAI+ FP L R+HG +V+H L++IY FL LA+VC Sbjct: 139 TTPFIDTHPTWRPRR-ENCSPPAIEQFPRPLMGPYARKHGGLVIHVLVAIYTFLGLAIVC 197 Query: 215 DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAV 394 D YFV ++++IC L ++ DV PEL VIG F + DIGV ++GSAV Sbjct: 198 DDYFVASLDRICEELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAV 257 Query: 395 FNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLY 574 FNI+ V + CG+ + V L+WWPL RDC Y I++ +++ I +E + W EA ++ +Y Sbjct: 258 FNIMFVISVCGLCSSTVSKLNWWPLCRDCFFYFISILVMLGTIANESISWGEALFMLIMY 317 Query: 575 GVYICIMYYDKPIQNFAK 628 GVY + ++ ++ +AK Sbjct: 318 GVYCVALAFNSTLERWAK 335 >UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).; n=1; Takifugu rubripes|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5). - Takifugu rubripes Length = 473 Score = 173 bits (421), Expect = 3e-42 Identities = 79/179 (44%), Positives = 113/179 (63%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 +C PP +FP G FT +R+ G +V++ LI Y+ LA+++VCD YF+P++E I L + Sbjct: 1 DCVPPQSSEFPDGFFTVQERKDGGLVIYFLIIFYMLLAVSIVCDDYFLPSLEVISERLGL 60 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 + DV PEL +G F+T+GDIGV TIVGSAV+N+L + A CG+ + Sbjct: 61 SQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGLLTTVA 120 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 L WPL RDCLAYGI+V+ +I II+D V WY+A L+ +Y VYI ++ +D I F Sbjct: 121 GRLTCWPLFRDCLAYGISVTAVIAIIYDNKVYWYDAASLLLVYMVYIVVLCFDLRISEF 179 >UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF15008, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 557 Score = 172 bits (419), Expect = 6e-42 Identities = 75/150 (50%), Positives = 105/150 (70%) Frame = +2 Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG 358 +IY+FLALAVVCD YFVP++EK+ L+++ DV PELF ++IG FITEG Sbjct: 1 AIYMFLALAVVCDVYFVPSLEKLSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEG 60 Query: 359 DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYV 538 D+GVGTIVGSAVFNIL + CGI AG + L WWPL RD + Y +++ +LI +I+DE V Sbjct: 61 DVGVGTIVGSAVFNILVIIGICGIFAGQPISLSWWPLFRDAVFYILSILVLILVIYDEKV 120 Query: 539 QWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 W+E +L+S+YG+YI IM +++ + + Sbjct: 121 MWWETIILISMYGIYIIIMKFNRSLHGLVE 150 >UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/potassium/calcium exchanger (Na(+)/K(+)/Ca(2+)-exchange protein); n=2; Endopterygota|Rep: PREDICTED: similar to Sodium/potassium/calcium exchanger (Na(+)/K(+)/Ca(2+)-exchange protein) - Apis mellifera Length = 658 Score = 169 bits (411), Expect = 5e-41 Identities = 76/181 (41%), Positives = 109/181 (60%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 N T FP LFT QR+ GA++LH + +Y+F+ALA+VCD++FVP+++ I L + Sbjct: 103 NMTEEKAPLFPQDLFTVHQRRRGAVILHVIGVVYMFVALAIVCDEFFVPSLDVIIEKLEI 162 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 +DV PELF ++IG F++ D+G+GTIVGSAVFNIL V C I + V Sbjct: 163 ADDVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAIFSRTV 222 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625 + L WWPL RDC Y ++ LI D Y+ WYEA +L Y Y+ M +++P++ Sbjct: 223 LSLTWWPLFRDCTFYSASLLTLIYFFRDNYIHWYEALVLFGFYLAYVSFMKWNQPMEKLV 282 Query: 626 K 628 K Sbjct: 283 K 283 >UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=20; Euteleostomi|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Homo sapiens (Human) Length = 500 Score = 168 bits (409), Expect = 9e-41 Identities = 72/183 (39%), Positives = 114/183 (62%) Frame = +2 Query: 74 GYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICH 253 G C +FP G FT +R+ G I+++ LI +Y+F+A+++VCD+YF+P++E I Sbjct: 41 GNSTQCVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISE 100 Query: 254 ALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIG 433 +L ++ DV PEL +G FIT+GDIG+ TI+GSA++N+L + A CG+ Sbjct: 101 SLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLL 160 Query: 434 AGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613 + V L WPL RDC AY I+ + ++ II+D V WYE LL+ +YG+Y+ ++ +D I Sbjct: 161 SNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKI 220 Query: 614 QNF 622 + Sbjct: 221 NQY 223 >UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=2; Culicidae|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 549 Score = 167 bits (405), Expect = 3e-40 Identities = 75/176 (42%), Positives = 104/176 (59%) Frame = +2 Query: 101 AIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVX 280 AID+ P +FT+ QR GAI+LH + +IY F LA + +YF+P+VE IC L +T DV Sbjct: 87 AIDELPDDVFTQEQRLQGAIILHFIGAIYFFTLLAYIVGEYFLPSVECICEDLKLTQDVA 146 Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW 460 PE F N I TFI + D+G+GTI+GS +FN L VA G+ V LDW Sbjct: 147 AATFMAIAGTIPEFFTNTISTFIADSDMGIGTIMGSLLFNTLGVACLAGLACKKPVQLDW 206 Query: 461 WPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 WP+TRDC+ + +S+L+ D + WYE+ + V L Y +M+ +KPI AK Sbjct: 207 WPITRDCIVFAFHISVLVGFAWDGRIYWYESMVFVILLFTYFVVMFQNKPIMKLAK 262 >UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein CG1090); n=5; Bilateria|Rep: Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein CG1090) - Drosophila melanogaster (Fruit fly) Length = 642 Score = 165 bits (402), Expect = 7e-40 Identities = 67/182 (36%), Positives = 114/182 (62%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNM 265 NCTPPAI+ FP L + RQHG ++LH L++++ F LA+VCD+YFV +++++C L + Sbjct: 101 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKL 160 Query: 266 TNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV 445 + DV PEL VIG F + DIG+ ++GSAVFNI+ V + C + +G V Sbjct: 161 SPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTV 220 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625 L+WWPL RDC Y +++ +++ II ++ + +E+ +++ Y Y ++++ ++ +A Sbjct: 221 CQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGYCVALHFNTELERWA 280 Query: 626 KG 631 G Sbjct: 281 LG 282 >UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 429 Score = 163 bits (397), Expect = 3e-39 Identities = 72/180 (40%), Positives = 110/180 (61%) Frame = +2 Query: 89 CTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMT 268 C PP I++FP + T+ QR +G ++LH + S++LF AL VVC+ +FV ++ +I L + Sbjct: 1 CRPPNIEEFPPDVLTQDQRFYGGVMLHVIFSLHLFCALTVVCEDFFVASLNRISMCLGLK 60 Query: 269 NDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 DV P LF+ +I F TEGDIG+GTIVGS +FN L + A C IG+G+ + Sbjct: 61 PDVAGATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTL 120 Query: 449 PLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 L +P++RD Y +V +L+ I+D V WYE + V +Y +YI IMY++ ++ K Sbjct: 121 QLACYPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMYFNDQVEGLCK 180 >UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C); n=7; Diptera|Rep: Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) - Drosophila melanogaster (Fruit fly) Length = 888 Score = 163 bits (396), Expect = 4e-39 Identities = 76/186 (40%), Positives = 114/186 (61%) Frame = +2 Query: 71 DGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKIC 250 D + N T FP LFT+ Q ++GA++LH + IY+F+ALA+VCD++FVP+++ I Sbjct: 304 DTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVII 363 Query: 251 HALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 L +T+DV PELF +VIG F++ D+G+GTIVGSAVFNIL V C + Sbjct: 364 EKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAL 423 Query: 431 GAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKP 610 + V+ L WWPL RDC Y I++ +LI D + W+EA +L ++Y Y+ M ++ Sbjct: 424 FSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQ 483 Query: 611 IQNFAK 628 ++ K Sbjct: 484 VETCVK 489 >UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exchanger; n=5; Coelomata|Rep: Potassium-dependent sodium-calcium exchanger - Aedes aegypti (Yellowfever mosquito) Length = 207 Score = 162 bits (394), Expect = 6e-39 Identities = 74/173 (42%), Positives = 109/173 (63%) Frame = +2 Query: 113 FPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXX 292 FP LFT QR++GA+VLH L IY+F+ALA+VCD++FVP+++ I L +T+DV Sbjct: 1 FPEDLFTLEQRRNGAVVLHILGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATF 60 Query: 293 XXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT 472 PELF +VIG F++ D+G+GTIVGSAVFNIL V C + + ++ L WWPL Sbjct: 61 MAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTLLTLTWWPLF 120 Query: 473 RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 631 RDC Y +++ LI D ++W+EA +L +Y Y M +++ ++ G Sbjct: 121 RDCTFYSVSLLTLIYFFRDNSIEWWEALVLFIIYIAYAVFMKFNQTVERCCGG 173 >UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to RE34149p - Nasonia vitripennis Length = 542 Score = 161 bits (390), Expect = 2e-38 Identities = 77/193 (39%), Positives = 110/193 (56%) Frame = +2 Query: 35 TTPLQNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVC 214 T P N + S + NC +I+DFP LFT QRQ GAI+ H +Y FL A VC Sbjct: 39 TKPPTNASESTNPA-VENCLAHSIEDFPEDLFTLQQRQQGAILFHIFFGLYCFLLTAFVC 97 Query: 215 DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAV 394 + Y +PA++ IC L ++ DV PELFVNV+GTF+TE D+GVG +VG AV Sbjct: 98 NDYLLPALDCICADLRISADVAGATFLATASCFPELFVNVVGTFLTESDLGVGAVVGGAV 157 Query: 395 FNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLY 574 FN A A + A + L W L+RDC+ Y +V +L+ ++ D V WYE+ +L+ L+ Sbjct: 158 FNTFATPAVGALFAAKGIQLQWHILSRDCVIYSFSVGVLVLVMWDGLVTWYESVILLFLF 217 Query: 575 GVYICIMYYDKPI 613 Y +++ + I Sbjct: 218 ASYFTLLFVNDSI 230 >UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=7; Murinae|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Mus musculus (Mouse) Length = 501 Score = 160 bits (388), Expect = 3e-38 Identities = 70/180 (38%), Positives = 108/180 (60%) Frame = +2 Query: 74 GYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICH 253 G C +FP G FT+ + G IV++ LI +Y+ +A+++VCDKYF+P++E I Sbjct: 41 GNSTQCAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISD 100 Query: 254 ALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIG 433 +L ++ DV PEL +G FIT+GDIG+ TI+GSA++N+L + A CG+ Sbjct: 101 SLGLSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLL 160 Query: 434 AGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613 + MV L WPL RDC Y ++V + II D + WYE L+ +YG+Y+ ++ +D I Sbjct: 161 SNMVSTLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTI 220 >UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=1; Aedes aegypti|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 520 Score = 159 bits (387), Expect = 4e-38 Identities = 74/175 (42%), Positives = 107/175 (61%) Frame = +2 Query: 101 AIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVX 280 ++DD P LF++ +R +GAI+LH L +IY F LA VC +YF+P+VE IC L+++ DV Sbjct: 66 SMDDLPPDLFSKTERLNGAIILHFLAAIYFFTILAYVCSEYFLPSVEYICEDLHLSEDVA 125 Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW 460 PE F N I T + + D+G+GTI+GS +FN L VAA G+ V LDW Sbjct: 126 AATFMATATSMPEFFTNTISTLVVDSDMGLGTIMGSMLFNTLGVAALVGLLTKSHVKLDW 185 Query: 461 WPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625 WPLTRD + I+ S L+ + DE V WYE+ + V LY +Y +M+ + ++ A Sbjct: 186 WPLTRDSIIVIISTSSLVSCLWDERVYWYESLVFVVLYVLYFLVMFQNDRMKRIA 240 >UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 639 Score = 159 bits (385), Expect = 8e-38 Identities = 68/172 (39%), Positives = 108/172 (62%) Frame = +2 Query: 125 LFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXX 304 +FT +R+HGA+++H I +Y F+ALA++CD YF ++EK+C L + DV Sbjct: 39 IFTLQERRHGAVIIHTFICLYCFVALAILCDNYFCASLEKLCKRLRIPTDVAGATFMAAG 98 Query: 305 XXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL 484 P LF+ + F+ EGDIG+GTI+GS++FNIL + A CG+ +GMV+ L WP+ RD Sbjct: 99 SSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVISLHTWPIVRDSC 158 Query: 485 AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGSWE 640 Y + + L+ +IHD + +YEA + LY YI IM ++ ++N + ++E Sbjct: 159 VYVVNLVGLLIVIHDNVIHFYEALIFPVLYTGYILIMVFNTRLENAFESAFE 210 >UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).; n=1; Danio rerio|Rep: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3). - Danio rerio Length = 419 Score = 156 bits (378), Expect = 5e-37 Identities = 74/147 (50%), Positives = 96/147 (65%) Frame = +2 Query: 182 IYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD 361 +Y+F ALA+VCD YFVP++EKIC L+++ DV PELF +VIG FIT+GD Sbjct: 1 MYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGD 60 Query: 362 IGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 541 +GVGTIVGSAVFNIL + CGI V L W L RD Y I V+ LI I+DE V Sbjct: 61 VGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVT 120 Query: 542 WYEAFLLVSLYGVYICIMYYDKPIQNF 622 W+E+ +L+ LY VYI IM ++ + +F Sbjct: 121 WWESLILIVLYLVYILIMKFNSRVVHF 147 >UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2); n=34; Euteleostomi|Rep: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) - Homo sapiens (Human) Length = 661 Score = 156 bits (378), Expect = 5e-37 Identities = 71/187 (37%), Positives = 113/187 (60%) Frame = +2 Query: 68 RDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKI 247 ++G N T A D+P +F+ +R+ GAI+LH + IY+F+ALA+VCD++FVP++ I Sbjct: 105 KEGESENSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVI 164 Query: 248 CHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG 427 L +++DV PELF ++IG FI ++G+GTIVGSAVFNIL V C Sbjct: 165 TEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCA 224 Query: 428 IGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607 + + ++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M ++ Sbjct: 225 LFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNV 284 Query: 608 PIQNFAK 628 ++ + K Sbjct: 285 QVEKWVK 291 >UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 1; n=2; Eutheria|Rep: Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 1 - Mus musculus (Mouse) Length = 1130 Score = 154 bits (374), Expect = 2e-36 Identities = 71/173 (41%), Positives = 108/173 (62%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P LF+ R+ G +VLH +Y+F+ALA+VCD+YFVPA+ I H L ++ DV Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGAT 465 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + + ++ L WWPL Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 RD Y + +S+LI D ++ W+E+ LL+ Y +Y+ M ++K I+ + K Sbjct: 526 FRDVSFYILDLSMLIVFFLDSFIAWWESLLLLLAYALYVFTMKWNKQIELWVK 578 >UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep: Slc24a2 protein - Mus musculus (Mouse) Length = 711 Score = 153 bits (370), Expect = 5e-36 Identities = 69/189 (36%), Positives = 112/189 (59%) Frame = +2 Query: 62 SERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVE 241 + ++ N T D+P +F+ +R+ GAI+LH + IY+F+ALA+VCD++FVP++ Sbjct: 104 ASQEDQAENSTEHTQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLT 163 Query: 242 KICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAAC 421 I L +++DV PELF ++IG FI ++G+GTIVGSAVFNIL V Sbjct: 164 VITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 223 Query: 422 CGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601 C + + ++ L WWPL RD Y + + +LI D + W+E+ LL++ Y Y+ M + Sbjct: 224 CALFSREILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKF 283 Query: 602 DKPIQNFAK 628 + ++ + K Sbjct: 284 NVQVERWVK 292 >UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - Morone saxatilis (Striped bass) Length = 749 Score = 151 bits (366), Expect = 2e-35 Identities = 73/173 (42%), Positives = 106/173 (61%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 D+P LF+ QRQ G +VLH + IY+F+ALA+VCD++FVP +E I + L +++DV Sbjct: 140 DYPEDLFSVEQRQQGWVVLHVIGMIYMFVALAIVCDEFFVPGLEVITNKLQISDDVAGAT 199 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF ++IG FI+ ++G+GTIVGSAVFNIL V C I + ++ L WWPL Sbjct: 200 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAIFSREMLHLTWWPL 259 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 RD Y + + +LI D + W+E+ LLV Y Y+ M ++ I+ K Sbjct: 260 FRDVSFYILDLIMLIVFFLDNTILWWESILLVLGYISYVSFMKFNSQIEQAVK 312 >UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 13 SCAF14555, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 647 Score = 150 bits (363), Expect = 4e-35 Identities = 72/179 (40%), Positives = 108/179 (60%), Gaps = 1/179 (0%) Frame = +2 Query: 95 PPAID-DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTN 271 PP + ++P LF+ R+ G +VLH + +Y+F+ALA+VCD++FVPA+ I H L +++ Sbjct: 126 PPQVKGEYPEDLFSIKDRRRGWVVLHIIGMMYMFIALAIVCDEFFVPALGVITHKLAISD 185 Query: 272 DVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 451 DV PELF ++IG FI ++G+GTIVGSAVFNIL V C + + V+ Sbjct: 186 DVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREVLH 245 Query: 452 LDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 L WWPL RD Y + + +LI D + W+E+ +LV Y VY+ M ++ I+ K Sbjct: 246 LTWWPLFRDVSFYILDLVMLIVFFLDNVIMWWESMMLVGGYTVYVIFMKFNVQIERAFK 304 >UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleostomi|Rep: Isoform 4 of Q9QZM6 - Rattus norvegicus (Rat) Length = 1153 Score = 149 bits (362), Expect = 5e-35 Identities = 70/173 (40%), Positives = 105/173 (60%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P LF+ R+ G +VLH Y+F+ALA+VCD+YFVPA+ I L ++ DV Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + + ++ L WWPL Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 RD Y + +S+LI D + W+E+ LL+ Y +Y+ M ++K I+ + K Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVK 578 >UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus norvegicus|Rep: Isoform 3 of Q9QZM6 - Rattus norvegicus (Rat) Length = 1086 Score = 149 bits (362), Expect = 5e-35 Identities = 70/173 (40%), Positives = 105/173 (60%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P LF+ R+ G +VLH Y+F+ALA+VCD+YFVPA+ I L ++ DV Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + + ++ L WWPL Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 RD Y + +S+LI D + W+E+ LL+ Y +Y+ M ++K I+ + K Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVK 578 >UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=13; Fungi/Metazoa group|Rep: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Rattus norvegicus (Rat) Length = 1181 Score = 149 bits (362), Expect = 5e-35 Identities = 70/173 (40%), Positives = 105/173 (60%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P LF+ R+ G +VLH Y+F+ALA+VCD+YFVPA+ I L ++ DV Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + + ++ L WWPL Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 RD Y + +S+LI D + W+E+ LL+ Y +Y+ M ++K I+ + K Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVK 578 >UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).; n=1; Takifugu rubripes|Rep: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2). - Takifugu rubripes Length = 449 Score = 149 bits (360), Expect = 8e-35 Identities = 70/176 (39%), Positives = 105/176 (59%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 D+P LFT +R+ G +VLH +Y+F+ALA+VCD++FVPA+ I L +++DV Sbjct: 2 DYPTDLFTIEERRQGYVVLHMFGMLYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 61 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF +VIG F++ ++G+GTIVGSAVFNIL V C + + V+ L WWPL Sbjct: 62 FMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGMCALFSKEVLHLTWWPL 121 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGSW 637 RD Y + + +LI D + E+ L+S YG Y+ M ++ + F K ++ Sbjct: 122 FRDVSFYIVGLLMLIYFFLDNQITVLESVSLLSFYGCYVTFMKFNSKFERFIKSAF 177 >UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=12; Euarchontoglires|Rep: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human) Length = 1099 Score = 148 bits (358), Expect = 1e-34 Identities = 78/210 (37%), Positives = 120/210 (57%), Gaps = 9/210 (4%) Frame = +2 Query: 26 ALHTTPLQNMNTS---ERDGYIRNCTPPAIDD------FPAGLFTELQRQHGAIVLHALI 178 A+ TTP ++ T+ E + PP++ D +P LF+ +R+ G +VLH Sbjct: 402 AMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFG 461 Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG 358 +Y+F+ALA+VCD+YFVPA+ I L ++ DV PELF ++IG FI+ Sbjct: 462 MMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHS 521 Query: 359 DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYV 538 ++G+GTIVGSAVFNIL V C + + ++ L WWPL RD Y + + +LI D + Sbjct: 522 NVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLI 581 Query: 539 QWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 W+E+ LL+ Y Y+ M ++K I+ + K Sbjct: 582 AWWESLLLLLAYAFYVFTMKWNKHIEVWVK 611 >UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Euteleostomi|Rep: Retinal rod Na/Ca+K exchanger - Tursiops truncatus (Atlantic bottle-nosed dolphin) Length = 1014 Score = 147 bits (357), Expect = 2e-34 Identities = 68/173 (39%), Positives = 106/173 (61%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P LF+ +R+ G +VLH +Y+F+ALA+VCD+YFVPA+ I L ++ DV Sbjct: 435 EYPRDLFSVKERRQGWVVLHIFGMLYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 494 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PELF ++IG FI+ ++G+GTIVGSAVFNIL V C + + ++ L WWPL Sbjct: 495 FMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 554 Query: 470 TRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 RD Y + + +LI D + W+E+ LL+ Y +Y+ M ++K ++ + K Sbjct: 555 FRDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTMKWNKQLELWVK 607 >UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|Rep: Na/Ca,K-exchanger - Caenorhabditis elegans Length = 596 Score = 147 bits (357), Expect = 2e-34 Identities = 71/187 (37%), Positives = 112/187 (59%), Gaps = 5/187 (2%) Frame = +2 Query: 83 RNCTPPAID-----DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKI 247 R+ PPA D FP F+ QRQ+G +VLH IY+F++LA+VCD++FVP+++ + Sbjct: 72 RSLAPPAPDVNDDGQFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDVL 131 Query: 248 CHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG 427 L++++DV PE F +VIG FI + ++G+GTIVGSA FNIL V A C Sbjct: 132 TEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCT 191 Query: 428 IGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607 + + ++ L WWPL RD Y + +++L+ DE + + EA + S+Y VY +M ++ Sbjct: 192 LFSKSILDLTWWPLFRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVYCTVMKFNG 251 Query: 608 PIQNFAK 628 ++ K Sbjct: 252 QLEQLVK 258 >UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 643 Score = 143 bits (347), Expect = 3e-33 Identities = 68/176 (38%), Positives = 104/176 (59%), Gaps = 2/176 (1%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P FT Q+Q GA++ H + Y+FLALA+ CD++FVP++ I L + DV Sbjct: 92 EYPEDEFTLEQKQQGAVICHIIGMCYMFLALAIACDEFFVPSLTVIIEKLELKEDVAGAT 151 Query: 290 XXXXXXXXPELFVNVIGTFI-TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP 466 PELF + IGTFI + ++G+GTIVGSAVFN+L V C + + V+ L WWP Sbjct: 152 FMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSKGVLELTWWP 211 Query: 467 LTRDCLAYGITVSILIC-IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKG 631 L RDC+ Y + + ILI + + + W+E+ +L+ Y Y+ M Y+ ++ KG Sbjct: 212 LFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYVIFMKYNHNVERRIKG 267 >UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5; n=2; Caenorhabditis|Rep: Putative uncharacterized protein ncx-5 - Caenorhabditis elegans Length = 591 Score = 142 bits (344), Expect = 7e-33 Identities = 64/164 (39%), Positives = 101/164 (61%) Frame = +2 Query: 113 FPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXX 292 FPA +F+ R+ G +++H + IY+F+ALAVVCD++FVP++ I L +++DV Sbjct: 19 FPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEVLAISDDVAGATF 78 Query: 293 XXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT 472 PE F ++ G F+ + ++GVGTIVGSA FNIL V A C + + V+ L WWPL Sbjct: 79 MAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHLTWWPLF 138 Query: 473 RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604 RD Y +++ +L+ DE ++W EA ++ S+Y Y M ++ Sbjct: 139 RDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAYGFFMKFN 182 >UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 209 Score = 136 bits (329), Expect = 5e-31 Identities = 64/135 (47%), Positives = 84/135 (62%), Gaps = 1/135 (0%) Frame = +2 Query: 41 PLQNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQ-HGAIVLHALISIYLFLALAVVCD 217 P N + ++ +NC P+I DFP+ T+ QRQ G IV H ++IY F ALA VCD Sbjct: 51 PSNNNSILNQETAAKNCVNPSISDFPSDFMTQYQRQKQGGIVFHVFVAIYTFAALATVCD 110 Query: 218 KYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVF 397 +YFV ++E+IC LN+ +DV PE F +VIG FIT+GDIG+GTIVGSAVF Sbjct: 111 EYFVSSLERICDGLNLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVF 170 Query: 398 NILAVAACCGIGAGM 442 NIL + A C G + Sbjct: 171 NILFIVAICAGGTAL 185 >UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amurensis|Rep: Na+/Ca2+ exchanger - Asterias amurensis (Starfish) Length = 616 Score = 135 bits (326), Expect = 1e-30 Identities = 63/156 (40%), Positives = 95/156 (60%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 + ++ ++ LF++LA++CD +FVP++E I L ++ DV PELF+++I Sbjct: 100 VTIYIILIFVLFISLAIICDDFFVPSLEAISERLELSEDVAGATFMAAGSSAPELFISII 159 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILIC 517 G E D+GVGTIVG+AVFNIL + A AG V+ LDW PL RDC++YGI++ I Sbjct: 160 GVS-KESDVGVGTIVGTAVFNILIIIALTAALAGQVLKLDWRPLVRDCISYGISIICFII 218 Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFA 625 D ++ YEA +L+ LY YI +M + I N + Sbjct: 219 FAWDGVIEIYEAIILLGLYVAYIVLMKLNSRIMNLS 254 >UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).; n=2; Tetrapoda|Rep: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3). - Xenopus tropicalis Length = 524 Score = 133 bits (322), Expect = 3e-30 Identities = 65/141 (46%), Positives = 90/141 (63%), Gaps = 2/141 (1%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 +FP +F+ R+HGA++LH L ++Y+F ALA+VCD +FVP++EKI L ++ DV Sbjct: 1 EFPDDIFSNEDRRHGAVILHVLFAMYMFYALAIVCDDFFVPSLEKISERLQLSEDVAGAT 60 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV--VPLDWW 463 PELF +VIG FIT+GD+GVGTIVGSAVFNIL + CG+ AG V + L Sbjct: 61 FMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVRSMLLVSL 120 Query: 464 PLTRDCLAYGITVSILICIIH 526 P CL Y + I + +I+ Sbjct: 121 PSPLQCLIYTHILYIYVFLIN 141 >UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calcium exchanger; n=2; Eumetazoa|Rep: Testis potassium dependent sodium/calcium exchanger - Strongylocentrotus purpuratus (Purple sea urchin) Length = 652 Score = 128 bits (309), Expect = 1e-28 Identities = 64/157 (40%), Positives = 92/157 (58%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 ++ +A+ I LF+A+A++CD +FVP++E I L+++ DV PELF VI Sbjct: 114 VIFYAIFVIILFIAIAIICDDFFVPSLEVISETLSLSEDVAGATFMAAGSSAPELFTAVI 173 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILIC 517 G E D+GVGTIVGSAVFNIL + A AG V+ LDW PL RD YG+++ I Sbjct: 174 GVAF-ESDVGVGTIVGSAVFNILIIIALTAALAGQVLNLDWRPLARDSFFYGLSLVCFIV 232 Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 D W+E+ +LV LY +Y+ +M + I + K Sbjct: 233 FSWDTEFTWWESLILVILYVIYLILMKVNPIIMDKTK 269 >UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).; n=2; Tetrapoda|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5). - Xenopus tropicalis Length = 555 Score = 124 bits (299), Expect = 2e-27 Identities = 63/179 (35%), Positives = 97/179 (54%), Gaps = 1/179 (0%) Frame = +2 Query: 89 CTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMT 268 C +FP FTE +R+ G +++H LI +Y+FLA+A+VC+ YF+P++E I L ++ Sbjct: 7 CIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLS 66 Query: 269 NDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAV-AACCGIGAGMV 445 DV PE +G F+T+GDIGV TIVGSAV+N+L + AACC + ++ Sbjct: 67 QDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSLL 126 Query: 446 VPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 L W + + IH + YE+ L+ +YG+YI M +D I + Sbjct: 127 YMLKVWRYVCPWMYFS--------TIHWDAWNRYESASLILIYGIYIVTMCFDIRINQY 177 >UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n=2; Ostreococcus|Rep: K-independent Na+/Ca2+ exchanger JSX - Ostreococcus tauri Length = 443 Score = 124 bits (299), Expect = 2e-27 Identities = 59/165 (35%), Positives = 93/165 (56%), Gaps = 2/165 (1%) Frame = +2 Query: 146 QHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELF 325 ++G VL+ + +Y+FL +A+VCD YFV ++EKIC L ++ DV PELF Sbjct: 35 RNGGWVLYVVGILYMFLGIAIVCDDYFVSSLEKICDKLGLSEDVAGATFMAAGSSAPELF 94 Query: 326 VNVIGTFITEG--DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGIT 499 + + + +IG+ IVGSAVFN+L + + AG + LDW P+TRDC+ Y + Sbjct: 95 SSGMSLISPDATNEIGISAIVGSAVFNMLFIVGATVLCAGCSLDLDWRPVTRDCMFYAMA 154 Query: 500 VSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAKGS 634 V ++ I +D + WYE + V LY Y+ M Y+ + + G+ Sbjct: 155 VLTVLLIFYDGRITWYEGLICVLLYATYVLCMCYNDVLMRWMGGA 199 >UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogaster|Rep: CG12061-PA.3 - Drosophila melanogaster (Fruit fly) Length = 353 Score = 122 bits (295), Expect = 6e-27 Identities = 59/122 (48%), Positives = 75/122 (61%) Frame = +2 Query: 263 MTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 MT DV PELFVN +GTF+T GDIG+GTIVGS+VFNIL +A CGI Sbjct: 1 MTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-Q 59 Query: 443 VVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNF 622 LDWWP+TRD Y I ++ L ++ D V WYEAF L+ LY Y+ + +D+ IQN Sbjct: 60 PTKLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNL 119 Query: 623 AK 628 + Sbjct: 120 VR 121 >UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isoform 1; n=2; Ostreococcus|Rep: Solute carrier family 24 member 4, isoform 1 - Ostreococcus tauri Length = 545 Score = 116 bits (280), Expect = 4e-25 Identities = 60/158 (37%), Positives = 86/158 (54%), Gaps = 2/158 (1%) Frame = +2 Query: 131 TELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXX 310 TE + G +V + + +YLF+ +A+VCD +FV ++EKIC L +++DV Sbjct: 57 TESWEKKGGLVAYFVGVVYLFIGIAIVCDDFFVASLEKICERLGLSDDVAGATFMAAGSS 116 Query: 311 XPELFVNVIGTFITEGD--IGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL 484 PEL + + + D IGVGTIVGSAVFNIL + I AG + LDW PL RDC Sbjct: 117 APELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIGATVIFAGETLKLDWRPLARDCT 176 Query: 485 AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 Y + + + V W+E + V LY +YI M+ Sbjct: 177 FYFAAIIGITLTFNGGVVNWWEGLIYVCLYMLYIAFMW 214 >UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodium-calcium potassium exchanger; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cone sodium-calcium potassium exchanger - Strongylocentrotus purpuratus Length = 651 Score = 113 bits (272), Expect = 4e-24 Identities = 56/120 (46%), Positives = 75/120 (62%) Frame = +2 Query: 47 QNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYF 226 Q M + G N T P +P LFT Q++ GAIVLH ++ IY+F+ALA+VCD++F Sbjct: 85 QGMQSVTDAGNASNNTQPNSGIYPRDLFTLQQKKDGAIVLHVILMIYMFVALAIVCDEFF 144 Query: 227 VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 406 VPA+ I L++++DV PELF ++IG F D+GVGTIVGSAVFNIL Sbjct: 145 VPALSVITDKLDLSDDVAGATFMAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204 >UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000012714 - Anopheles gambiae str. PEST Length = 386 Score = 113 bits (271), Expect = 5e-24 Identities = 54/110 (49%), Positives = 68/110 (61%) Frame = +2 Query: 101 AIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVX 280 ++DD P LFTE QR GAIVLH L +IY F+ LA VC +YF+P+VE +C L ++ DV Sbjct: 2 SLDDLPPDLFTEEQRLQGAIVLHFLAAIYFFMLLAYVCSEYFLPSVECLCEDLKLSQDVA 61 Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PE F N I T + DIGVGTI+GS +FN L VAA G+ Sbjct: 62 AATFMATATSMPEFFTNTISTLAVDSDIGVGTIMGSMLFNTLGVAALVGL 111 >UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc:153443 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 231 Score = 100 bits (239), Expect = 4e-20 Identities = 46/96 (47%), Positives = 65/96 (67%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 ++P LFT QR+ GA+VLH +Y+F+ALA+VCD++FVPA+ I L +++DV Sbjct: 116 EYPEDLFTLEQRRQGAVVLHMFGMMYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 175 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVF 397 PELF +VIG FI+ ++G+GTIVGSAVF Sbjct: 176 FMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211 >UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaster|Rep: CG17167-PA - Drosophila melanogaster (Fruit fly) Length = 441 Score = 97.9 bits (233), Expect = 2e-19 Identities = 46/109 (42%), Positives = 65/109 (59%) Frame = +2 Query: 104 IDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXX 283 +D+F A LFT Q + G +VLH ++Y F+ LA++C+ YF+P VE IC L+++ DV Sbjct: 66 MDEF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAA 124 Query: 284 XXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PE F N I T I E D+G+GTI+GS +FN L VA + Sbjct: 125 ATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAAL 173 >UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061-PB.3 - Drosophila melanogaster (Fruit fly) Length = 110 Score = 97.5 bits (232), Expect = 3e-19 Identities = 48/96 (50%), Positives = 59/96 (61%) Frame = +2 Query: 251 HALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 +AL MT DV PELFVN +GTF+T GDIG+GTIVGS+VFNIL +A CGI Sbjct: 15 NALRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGI 74 Query: 431 GAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYV 538 LDWWP+TRD Y I ++ L ++ D V Sbjct: 75 FT-QPTKLDWWPVTRDTAWYLIAIASLTYVLWDSLV 109 >UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis pacifica SIR-1|Rep: Ca2+/Na+ antiporter - Plesiocystis pacifica SIR-1 Length = 361 Score = 82.2 bits (194), Expect = 1e-14 Identities = 43/146 (29%), Positives = 78/146 (53%), Gaps = 3/146 (2%) Frame = +2 Query: 170 ALISIYL-FLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTF 346 A++++ + F A++ V + F+ ++++I + +++ V PEL ++ F Sbjct: 6 AIVTVLVAFYAMSAVVEGPFMASLDRIAERMGLSSSVAGATLLAFGTSAPELSTALVALF 65 Query: 347 I--TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI 520 GVG+IVGSA+F IL V + LDW P+ RD L Y +++ +LI Sbjct: 66 AEGAHASTGVGSIVGSAIFQILVVVGFAAVVRAST--LDWRPVIRDALFYALSIVLLIAF 123 Query: 521 IHDEYVQWYEAFLLVSLYGVYICIMY 598 +HD+ + EA +LV YG+Y+ +M+ Sbjct: 124 VHDDRLTLVEAAILVGSYGLYLGVMW 149 Score = 33.1 bits (72), Expect = 6.4 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 7/133 (5%) Frame = +2 Query: 221 YFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFN 400 + V A E I AL + + PEL + D+ V VGS +F+ Sbjct: 225 WLVFAAEAIAQALAVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVANAVGSNIFD 284 Query: 401 ILA-----VAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAF--L 559 IL V C + G +V L +T + G T+++++ ++ + + AF L Sbjct: 285 ILVSLGLPVLLYC-LLHGDLVGLGGATITSSLVLLGATLAMVVGLLAAQRFRASRAFGAL 343 Query: 560 LVSLYGVYICIMY 598 L+S Y Y+ Y Sbjct: 344 LISAYAAYVVAAY 356 >UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/calcium ion; n=2; Ostreococcus|Rep: CaCA family transporter: sodium ion/calcium ion - Ostreococcus lucimarinus CCE9901 Length = 603 Score = 65.3 bits (152), Expect = 1e-09 Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 11/162 (6%) Frame = +2 Query: 176 ISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG----- 340 +++ LF ALA V +++FVPA+ I L + +DV P++F + Sbjct: 95 LALTLFAALASVAERFFVPALRNIARGLALRDDVAGATLLSFGNGAPDIFAQIAALSHED 154 Query: 341 ----TFITEGDI-GVGTIVGSAVFN-ILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITV 502 + G + G G + S VF ++ +A G G+V LD W RD Y + Sbjct: 155 VAESAALAVGAVTGAGAFIASFVFPCVVLIATRAASGRGLV--LDKWNFGRDVGFYAVAS 212 Query: 503 SILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQNFAK 628 ++ + D V+ YEA L SLY Y+ ++ + ++ FA+ Sbjct: 213 AMALGFFLDGRVEAYEAAALFSLYAAYLFVLLSGRRLKRFAR 254 >UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger-like protein; n=1; Microscilla marina ATCC 23134|Rep: Putative K+-dependent Na+/Ca+ exchanger-like protein - Microscilla marina ATCC 23134 Length = 389 Score = 64.5 bits (150), Expect = 2e-09 Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 6/149 (4%) Frame = +2 Query: 170 ALISIYL-FLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTF 346 AL+ I L F + + D++F+ +++ I + + V PE+ + F Sbjct: 6 ALVVILLAFYVMTEIVDRHFIKSLDNIAEWMKLPPSVAGATLLALGTSAPEISTALFALF 65 Query: 347 ITEGD--IGVGTIVGSAVFNILAVAACCGIGAGMVVP---LDWWPLTRDCLAYGITVSIL 511 + + GVGTIVGSA+F IL V IG VV L+W P+ RD + Y +V +L Sbjct: 66 LEGANPATGVGTIVGSAIFQILVV-----IGFAAVVKTSYLNWRPVMRDSIFYAFSVGLL 120 Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 I + D E V Y +Y+ +++ Sbjct: 121 ILFVADNKFTLIEGIAFVCSYFLYLFVLF 149 Score = 34.3 bits (75), Expect = 2.8 Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 7/148 (4%) Frame = +2 Query: 176 ISIYLFLALAVVCDKYF-VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 I ++L + + YF V A E + A+++ + PE+ + I Sbjct: 235 IPVFLLSLVIIAGASYFLVVAAEALAKAMDIPPAIIALTILAGGSSIPEMISSAIVAKQG 294 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSI------LI 514 GD+ + +GS +F+IL G+ + + + PLT D IT SI LI Sbjct: 295 RGDMAIANAIGSNIFDIL---MSLGLPVLIYILIKGQPLT-DLGGANITSSIILLFTTLI 350 Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMY 598 ++ +VQ ++A L+ +++ ++Y Sbjct: 351 VVVLLLFVQKFKATRPFGLFLIFLYLIY 378 >UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependent Na/Ca exchanger NCKX4, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to K-dependent Na/Ca exchanger NCKX4, partial - Strongylocentrotus purpuratus Length = 76 Score = 61.7 bits (143), Expect = 2e-08 Identities = 27/55 (49%), Positives = 38/55 (69%) Frame = +2 Query: 86 NCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKIC 250 NCT I FP G+FT QR+ GA+V++ L+S+YL A+ VC YFVP++E +C Sbjct: 21 NCTVRGISKFPRGVFTNEQRKGGALVVNFLVSLYLCGAIGYVCAAYFVPSLEILC 75 >UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger NCKX1; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger NCKX1 - Ornithorhynchus anatinus Length = 543 Score = 58.4 bits (135), Expect = 1e-07 Identities = 23/70 (32%), Positives = 42/70 (60%) Frame = +2 Query: 422 CGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601 C + + ++ L WWPL RD Y + + +LI D V W+E+ LL++ Y +Y+ M + Sbjct: 144 CALCSREILRLTWWPLFRDVSFYILDLLMLIAFFSDGTVAWWESLLLLAAYALYVFAMKW 203 Query: 602 DKPIQNFAKG 631 ++P++ + KG Sbjct: 204 NRPLEAWVKG 213 Score = 48.8 bits (111), Expect = 1e-04 Identities = 19/43 (44%), Positives = 32/43 (74%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAV 238 ++P +F+ +R+ G ++LH Y+F+ALA+VCD+YFVPA+ Sbjct: 87 EYPEDVFSVEERRRGWVLLHVSGMAYVFVALAIVCDEYFVPAL 129 >UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus kandleri|Rep: Ca2+/Na+ antiporter - Methanopyrus kandleri Length = 329 Score = 55.2 bits (127), Expect = 1e-06 Identities = 29/94 (30%), Positives = 51/94 (54%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PE ++ + ++GVGTI+GSAV+N+ + + AG + L+ RD L Y Sbjct: 73 PEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGLAALAAGGLT-LERAVYRRDVLFYL 131 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595 + + +++ + D V EA V+LYG+Y+ +M Sbjct: 132 LALVVVLVSLWDRVVLRVEALAWVALYGLYVLLM 165 >UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_5, whole genome shotgun sequence - Paramecium tetraurelia Length = 536 Score = 53.6 bits (123), Expect = 4e-06 Identities = 47/176 (26%), Positives = 72/176 (40%), Gaps = 3/176 (1%) Frame = +2 Query: 77 YIR-NCTPPAIDDFPAGLFTELQRQHGAIVLHA-LISIYLFLALAVVCDKYFVPAVEKIC 250 Y++ NC I F F +L ++L A L+ +LF LA D Y PAV I Sbjct: 19 YVKENCNDQEIFKFTHYYFCQLDENWVILILIAPLLFFFLFNFLARTVDDYLSPAVTFIA 78 Query: 251 HALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD-IGVGTIVGSAVFNILAVAACCG 427 M+ P+ F V+ + +G I VG+I GS + V Sbjct: 79 EYFKMSQTFAGVTLIAFANGVPDFFCAVLASQDDDGILIAVGSIFGSCLCMTTLVFGAVI 138 Query: 428 IGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595 + +G ++ P RD L G+ + +L+ + Y A SLY VYI ++ Sbjct: 139 LFSG-IIKAQKVPFIRDILFNGVAIFLLMVFAFIGQINHYMAIGFCSLYLVYIVVV 193 >UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antiporter; n=1; Pirellula sp.|Rep: Probable sodium/calcium exchanger antiporter - Rhodopirellula baltica Length = 432 Score = 51.2 bits (117), Expect = 2e-05 Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 16/154 (10%) Frame = +2 Query: 182 IYLFLALAVV---CDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 + +FL V+ CD + + A E I N++ V PELF +I F+ Sbjct: 8 VLIFLTCLVIWRACDGFEI-ASEYI--GRNLSEGVRGGTINAISSSIPELFTTLIALFVL 64 Query: 353 EG----DIGVGTIVGSAVFNILAVAACCGIGA-GMVVP--------LDWWPLTRDCLAYG 493 IG+GT GSA+FN + + A C + G VV + L RD ++ Sbjct: 65 SDRDGFSIGIGTTAGSALFNGMIIPAVCILSVVGFVVMGVRVTSVNVSTRVLLRDGISLI 124 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595 + ILI +I+ E + W++ +L+ +Y Y+ M Sbjct: 125 LCEFILILLINGEQLHWWQGLILMLMYATYLVYM 158 >UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 313 Score = 50.0 bits (114), Expect = 5e-05 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 2/153 (1%) Frame = +2 Query: 134 ELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXX 313 E Q +H A+ A++ L + V + V I L ++ V Sbjct: 160 EEQPKHWAVDTLAIVG---GLVVLVFASRLLVDNAVSIAKELGVSEAVIGLTIVAAGTSM 216 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTR-DCLA- 487 PEL +++ + + DI +G IVGS +FNIL +A C ++ P++ + D L Sbjct: 217 PELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSC----SLIHPIEAKNVNYIDLLVM 272 Query: 488 YGITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586 GI+V +L + + + E F+L+ Y +Y+ Sbjct: 273 LGISVLLLPLVKSGQKISRTEGFVLILFYVIYM 305 Score = 36.7 bits (81), Expect = 0.52 Identities = 16/30 (53%), Positives = 21/30 (70%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNI 403 PEL V++ T +GDI +G IVGS +FNI Sbjct: 52 PELVVSLNATLSGQGDIAIGNIVGSNIFNI 81 >UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 1117 Score = 48.0 bits (109), Expect = 2e-04 Identities = 31/143 (21%), Positives = 64/143 (44%), Gaps = 1/143 (0%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 ++L + ++LF + VV +F P + I L + P++F + Sbjct: 181 LLLILMWMLFLFSWVGVVASDFFCPNLSTIASRLGLNESTAGVTFLAFGNGSPDVF-STF 239 Query: 338 GTFITE-GDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILI 514 G T+ G + +G ++G+A F + ++ + A V + WP RD + + V++ + Sbjct: 240 GAMKTDSGSLAIGELLGAASFIVSVISGSMMLIAPFKV--NAWPFCRDVGFFTVAVALTL 297 Query: 515 CIIHDEYVQWYEAFLLVSLYGVY 583 + D ++ E L+ LY +Y Sbjct: 298 TFLFDGKLRRIETIALICLYLLY 320 >UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus ferrooxydans PV-1|Rep: Ca2+/Na+ antiporter - Mariprofundus ferrooxydans PV-1 Length = 322 Score = 47.6 bits (108), Expect = 3e-04 Identities = 35/150 (23%), Positives = 68/150 (45%), Gaps = 6/150 (4%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 +L+ + LAL ++ + V +I H L +++ + PEL +++ Sbjct: 172 SLLWFVVGLALLIISSRMVVWGAVEIAHLLGVSDLIIGLTIVAIGTSLPELVASLVSALK 231 Query: 350 TEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDC-LAYGITVSILICII 523 E D+ +G ++GS +FN+LAV A I G P L RD + G T+++ + Sbjct: 232 GEADLAIGNVIGSNMFNLLAVLAMPALIHPGAFAP---EALMRDFPIMIGFTIALFVVSF 288 Query: 524 ----HDEYVQWYEAFLLVSLYGVYICIMYY 601 + +E LL + + Y+ ++Y+ Sbjct: 289 ALKKSGGVINRFEGGLLTAGFAGYLILLYF 318 >UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr8 scaffold_150, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 593 Score = 47.6 bits (108), Expect = 3e-04 Identities = 31/136 (22%), Positives = 60/136 (44%), Gaps = 2/136 (1%) Frame = +2 Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG-TFITEGDI 364 LF L YF ++E + L ++ + ++F +++ T ++GD+ Sbjct: 121 LFYLLGNTAANYFCSSLENLSRVLKLSPTIAGVTLLSLGNGAADVFASIVSFTRTSDGDV 180 Query: 365 GVGTIVGSAVFNILAVAACCGIGAG-MVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 541 G+ ++G A F V I G + +D RD + + I ++ L+ II V Sbjct: 181 GLNIVLGGAFFVSSVVVGIISIFIGPRQISVDKPSFIRDVIFFLIALASLLVIIIIGKVS 240 Query: 542 WYEAFLLVSLYGVYIC 589 ++ + VS+Y Y+C Sbjct: 241 FWGSVCFVSIYFFYVC 256 >UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenorhabditis|Rep: Na/ca exchangers protein 8 - Caenorhabditis elegans Length = 703 Score = 47.6 bits (108), Expect = 3e-04 Identities = 31/147 (21%), Positives = 67/147 (45%), Gaps = 4/147 (2%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELF---V 328 I++ + I+LF+ ++ + D +F P++ I L M+ + P++F Sbjct: 105 IIVGIIYLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSIS 164 Query: 329 NVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVS- 505 +V+ T + + +G + G+++F V A V + P RD + Y IT++ Sbjct: 165 SVLSTPKPKAALALGDLFGTSIFVTTVVLAIIIFTKSFKVAI--IPTLRDLIFYMITLAF 222 Query: 506 ILICIIHDEYVQWYEAFLLVSLYGVYI 586 I C + + ++ + + +Y VY+ Sbjct: 223 ITFCFLKFDKIEVWMPATFLGIYAVYL 249 >UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr0681 protein - Synechocystis sp. (strain PCC 6803) Length = 433 Score = 47.2 bits (107), Expect = 4e-04 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 1/138 (0%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 +AL V+ V + I +L ++ V PEL +V+ ++ E DI VG Sbjct: 252 VALLVLGSSLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSVVASYRGERDIAVG 311 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAYGITVSILICIIHDEYVQWYE 550 +VGS +FNILAV I + + + D + + + + L I + +E Sbjct: 312 NVVGSNIFNILAVLGFAAIFSPNGIQVSNSAFNFDIPVMFAVALVCLPVFITGRLIDRWE 371 Query: 551 AFLLVSLYGVYICIMYYD 604 FL + Y Y + D Sbjct: 372 GFLFLFYYIAYTAYLVLD 389 Score = 39.1 bits (87), Expect = 0.097 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 PE+ V++ + DI +G +VGS +FN+L + C I ++V Sbjct: 119 PEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPLIV 163 >UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Halothermothrix orenii H 168|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Halothermothrix orenii H 168 Length = 383 Score = 47.2 bits (107), Expect = 4e-04 Identities = 41/186 (22%), Positives = 73/186 (39%), Gaps = 2/186 (1%) Frame = +2 Query: 47 QNMNTSERDGYIRNCTPPAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYF 226 Q TS G N PA D + + ++VL + ++ + L + K Sbjct: 198 QTAATSISRGSNANQPTPAQSDVSVEI--TISEDSDSLVLR-IFKLFAGIFLVIGSSKVL 254 Query: 227 VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 406 +PAVE + + + PEL + G++ VG IVG+ + N+L Sbjct: 255 IPAVEITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAVGNIVGADILNVL 314 Query: 407 AV--AACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGV 580 V +A G+ VP +++ L + + L +E + E +L LY + Sbjct: 315 FVVGSAASVTAGGLNVPANFYRLQIPTMVIILVTFRLFSRGRNEEITKKEGIVLFLLYVI 374 Query: 581 YICIMY 598 Y+ + Y Sbjct: 375 YLILNY 380 >UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 433 Score = 46.8 bits (106), Expect = 5e-04 Identities = 35/170 (20%), Positives = 72/170 (42%), Gaps = 1/170 (0%) Frame = +2 Query: 155 AIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNV 334 A+V+ ++ ++LF+ L + D YF P++ I L ++ +V P++F + Sbjct: 34 ALVILFVLMLFLFIVLGITADDYFCPSLTVISKTLRLSQNVAGVTFLAYGNGAPDIF-SA 92 Query: 335 IGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILI 514 I +G+ +F V + G L+ P TRD L Y VS + Sbjct: 93 IAAVSAHSKNPNAAQLGAGIFVTTVVVGSVTLCTG-GFHLNNRPFTRDVLFYLGAVSWMF 151 Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI-QNFAKGSWEMGIKHVQ 661 ++ + + EA + Y Y+ ++ + + Q + + E+ K ++ Sbjct: 152 ITMYRQRITMLEAIGFIIFYFAYVVVVIVGRYVNQRWKRRQEEVDTKFIK 201 >UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein precursor; n=2; Chlorobiaceae|Rep: K+-dependent Na+/Ca+ exchanger related-protein precursor - Chlorobium phaeobacteroides BS1 Length = 325 Score = 46.4 bits (105), Expect = 6e-04 Identities = 32/127 (25%), Positives = 56/127 (44%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 LA ++ K V A I AL + + PEL +++ TF + DI VG Sbjct: 189 LAGLLLGGKLSVDAAVGIAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVG 248 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEA 553 +VGS +FN+L V C + VP++ + + + I H + + +E Sbjct: 249 NVVGSNIFNLLLVNGVCSSITQIAVPVNGGFYDLFMMILLAVFLLPMSITHKKKIVRWEG 308 Query: 554 FLLVSLY 574 +L+++Y Sbjct: 309 AVLLAMY 315 >UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related family protein; n=1; Dichelobacter nodosus VCS1703A|Rep: K+-dependent Na+-Ca+ exchanger related family protein - Dichelobacter nodosus (strain VCS1703A) Length = 325 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 2/108 (1%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 L L ++ + V I ALN+++ + PEL +++ + D+ +G Sbjct: 180 LVLLIIASRIMVWGAVSIAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALG 239 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLAYGITVSIL 511 IVGS +FN LAV +G++ P P LTRD + I ++L Sbjct: 240 NIVGSNIFNALAVVGL----SGLITPFAAEPEILTRDLVVMTIVTAVL 283 Score = 32.7 bits (71), Expect = 8.4 Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 5/143 (3%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340 ++ A+ +I + L L V +FV + ++ V PE+ V+V Sbjct: 3 IIWAIGAIIIGLILLVKSADWFVDGAAALAKIAGLSPLVIGIVIIGFGTSAPEMIVSVTA 62 Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI 520 I +G GS NI+ + GI A ++ P+ P+ + ++ + + +LI + Sbjct: 63 ALNHNSGIALGNAYGS---NIVNIGLILGISA-LIAPI---PMPKKLVSGELFILLLITL 115 Query: 521 -----IHDEYVQWYEAFLLVSLY 574 + D+Y+ EA +++ L+ Sbjct: 116 LCFLWLQDDYISRSEALVMLVLF 138 >UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis thaliana|Rep: AT5g17860/MVA3_210 - Arabidopsis thaliana (Mouse-ear cress) Length = 570 Score = 46.4 bits (105), Expect = 6e-04 Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 2/147 (1%) Frame = +2 Query: 152 GAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVN 331 G +VL A + + LF L YF P+++ + L ++ + P+LF + Sbjct: 101 GHLVLSAWLFV-LFYLLGDTAASYFCPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSS 159 Query: 332 VIG-TFITEGDIGVGTIVGSAVF-NILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVS 505 V+ T GD G+ +I+G A F + V C + V +D RD + + + Sbjct: 160 VVSFTRSNNGDFGLNSILGGAFFVSSFVVGTICVLIGSRDVAIDRNSFIRDVVFLLVALC 219 Query: 506 ILICIIHDEYVQWYEAFLLVSLYGVYI 586 L II V + A +S+Y +Y+ Sbjct: 220 CLGLIIFIGKVTIWVALCYLSIYLLYV 246 >UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family - Parvibaculum lavamentivorans DS-1 Length = 334 Score = 46.0 bits (104), Expect = 8e-04 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PE+ +V+ F + DI +G +VGS +FN+L +A + + VP D D G Sbjct: 240 PEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPVPVPADIAGF--DIWVMG 297 Query: 494 -ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595 ++ L+ + EA LL+ YG Y+ ++ Sbjct: 298 AASLLFLVFAWTGSRIGRVEALLLLGGYGAYVTVL 332 Score = 33.1 bits (72), Expect = 6.4 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 4/102 (3%) Frame = +2 Query: 185 YLFLALAVVC----DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 YLFL + +V ++ V + L ++ + PEL ++ G F Sbjct: 20 YLFLVVGLVLLLGGAEFLVKGAASLATRLGVSPFLIGLTLVGFGTSAPELVASLEGAFQG 79 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD 478 I VG +VGS + NIL + G+ M V D L RD Sbjct: 80 YPGIAVGNVVGSNIANILLILGIAGLIFPMTV--DRGALKRD 119 >UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|Rep: K-exchanger-like protein - Sorghum bicolor (Sorghum) (Sorghum vulgare) Length = 573 Score = 46.0 bits (104), Expect = 8e-04 Identities = 33/147 (22%), Positives = 64/147 (43%), Gaps = 4/147 (2%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 AL + LF L +YF ++E + AL + V P++F +V+ Sbjct: 113 ALWLVVLFYLLGDTASEYFCASLEGLSAALRLPPAVAGVTLLSLGNGAPDVFASVVSFAS 172 Query: 350 TEGD-IGVGTIVGSAVFNILAVAACCGIGAGMV---VPLDWWPLTRDCLAYGITVSILIC 517 +G +G+ + +G A+F VA + G V ++W RD + + L+ Sbjct: 173 GDGGGVGLSSALGGALFVSTVVAGVVALAVGGARGGVVVEWRGFVRDLCFLLLALCYLLA 232 Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMY 598 ++ + + + A VSLY Y+ +++ Sbjct: 233 VLVNGVITVWVAVSFVSLYVGYVVLVW 259 >UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep: Ca2+/Na+ antiporter - Idiomarina loihiensis Length = 325 Score = 45.6 bits (103), Expect = 0.001 Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 6/165 (3%) Frame = +2 Query: 107 DDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXX 286 DD A FTE + + A++ + + L L +V + V I +L +++ V Sbjct: 152 DDSLAAEFTEELDSNPLPMKPAIMWLIVGLLLLIVSSRALVWGAVNIAVSLGVSDLVIGL 211 Query: 287 XXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP 466 PEL + T E D+ +G ++GS +FN LAV GI AG + P+ P Sbjct: 212 TVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNMFNTLAVV---GI-AGAIEPVSLEP 267 Query: 467 --LTRDCLAYGITVSILICI----IHDEYVQWYEAFLLVSLYGVY 583 L+RD +A + +L+ + F+ + LY +Y Sbjct: 268 LVLSRDWVAMAVLTLLLMVFGIRKARQGRINRVHGFIFICLYLLY 312 >UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Clostridium oremlandii OhILAs|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Clostridium oremlandii OhILAs Length = 310 Score = 45.6 bits (103), Expect = 0.001 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 2/157 (1%) Frame = +2 Query: 134 ELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXX 313 +L RQ ++ H L + L + V+ Y V A KI L + Sbjct: 156 DLNRQSMDLI-HILFYLVLGIIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSL 214 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL ++ DI VG I+GS +FNIL V + + ++ P+ + LA+ Sbjct: 215 PELITCLVACHKKNDDIAVGNIIGSNIFNILFVLSV----SSLISPIAFSSHLIIDLAFM 270 Query: 494 ITVSILICIIH--DEYVQWYEAFLLVSLYGVYICIMY 598 + + L+ I + + E F+L+ LY Y +Y Sbjct: 271 LLFTFLLFIFSYTHKKISRLEGFVLMMLYLFYFVFIY 307 >UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-protein precursor; n=4; Proteobacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein precursor - Desulfovibrio desulfuricans (strain G20) Length = 322 Score = 45.2 bits (102), Expect = 0.001 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 3/121 (2%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340 + A+ + + L L VV + V +I H +++ + PEL ++I Sbjct: 170 IRRAVFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIA 229 Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLAY-GITVSIL 511 T E DI +G ++GS +FN LAV GI AG + P+ P RD + G+T+S+ Sbjct: 230 TRKGEHDIALGNVLGSNLFNTLAVV---GI-AGAIHPMAIGPEVFNRDMMVMAGLTLSLF 285 Query: 512 I 514 + Sbjct: 286 V 286 >UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneumophila|Rep: Na/Ca antiporter - Legionella pneumophila (strain Corby) Length = 319 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/86 (26%), Positives = 40/86 (46%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 L+SI + L + +C KY V +I ++ PEL +++ Sbjct: 173 LLSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKG 232 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGI 430 E I +GTI+GS ++N+L + A G+ Sbjct: 233 EDSIAIGTIIGSNIYNLLLILALPGL 258 >UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobacteriales|Rep: Sodium/calcium exchanger - Robiginitalea biformata HTCC2501 Length = 315 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL-AY 490 PEL +VI E + VG ++GS +FN+LAV I A + V LD LTRD Sbjct: 218 PELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGLTAILAPVPV-LDDRLLTRDVFWML 276 Query: 491 GITVSILICIIHDEYVQ--WYEAFLLVSLYGVYI 586 GI+ +L + + ++ W + +L++ YG ++ Sbjct: 277 GISFLVLPLVFFPKGLRLGWRDGIVLLACYGAFL 310 >UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 974 Score = 44.4 bits (100), Expect = 0.003 Identities = 33/148 (22%), Positives = 64/148 (43%), Gaps = 2/148 (1%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 I+ I +LF + + +F P + + L + P++F Sbjct: 79 ILFLLFILAFLFSFIGISAADFFCPNLSTVAAYLGLNESTAGVTFLAFGNGSPDVFSTF- 137 Query: 338 GTFITEGDIG--VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL 511 + ++ G +G VG ++G+A F + V VP + RD + + I V +L Sbjct: 138 -SAMSSGTLGLAVGELIGAASFIVSIVVGSIAFIRPFHVPKN--AFRRDVIFFTIAVLML 194 Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYICIM 595 I +HD ++ + E+ +V LY VY+ ++ Sbjct: 195 IVALHDGHLTFAESGSMVGLYVVYVGVV 222 >UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=2; Mycobacterium|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 335 Score = 44.0 bits (99), Expect = 0.003 Identities = 34/142 (23%), Positives = 65/142 (45%) Frame = +2 Query: 98 PAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277 PA DD A ++ G++V + ++I + + + VV + V I +++ + Sbjct: 166 PAGDDGAAEREPDMP-DTGSLVRYFAMTI-VGITVVVVGADWLVEGAVGIAREFGVSDAL 223 Query: 278 XXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457 PEL ++ T E DI +G ++GS+V+NI+ + +GA +VP D Sbjct: 224 IGLTIVAIGTSAPELVTTIVSTVRGERDIAIGNLLGSSVYNIVLI-----LGATCLVPAD 278 Query: 458 WWPLTRDCLAYGITVSILICII 523 PL + I V ++ ++ Sbjct: 279 GLPLNSSLVWIDIPVMVVATLL 300 >UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3; n=2; Caenorhabditis|Rep: Putative uncharacterized protein ncx-3 - Caenorhabditis elegans Length = 807 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Frame = +2 Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG-MVVPLDWWPLTRDCLAYG--- 493 + ++G GD+G GTIVGSA FN+ ++A C G ++ + + +G Sbjct: 112 IEIVGNGFKAGDLGPGTIVGSAAFNLFCISAICVFAVGTQTKRIELYRVFVVTAFFGTFA 171 Query: 494 -ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 I V +++ +I V +EA L + + + + + Y Sbjct: 172 YIWVFLVLIVITPNVVDVWEAILTLLFFIILVVVSY 207 >UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: Uvs037 - uncultured bacterium Length = 354 Score = 43.6 bits (98), Expect = 0.005 Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 8/142 (5%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 L L V+ ++ V + ++ + + V PE+ +V+ T E DI VG Sbjct: 178 LVLLVLGARWLVQSAVELATSWGVNEAVIGLTIVAAGTSLPEVVTSVVATIKGERDIAVG 237 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL-----ICI---IHD 529 +VGS +FNIL V GI +G+V P+ PL G + ++ +C+ Sbjct: 238 NVVGSNIFNILCV---LGI-SGLVSPI---PLLAGEQLAGFDIPVMLGVAALCVPLFFVG 290 Query: 530 EYVQWYEAFLLVSLYGVYICIM 595 + E FL ++LY Y+ I+ Sbjct: 291 AILNRMEGFLFLTLYVAYVWIL 312 Score = 33.9 bits (74), Expect = 3.7 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL V+V F + ++ + +VGS +FNIL + + + +++ L R + Sbjct: 50 PELAVSVKAAFSGQAELAIANVVGSNIFNILFILGVAALISPLIIS---HQLIRQDVPIM 106 Query: 494 ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601 + VSI+ + + D + EA +L Y ++Y Sbjct: 107 VGVSIVAVLMTLDGNINKLEASILTIGLISYTWFLFY 143 >UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=4; Chlorobium|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Chlorobium ferrooxidans DSM 13031 Length = 318 Score = 43.6 bits (98), Expect = 0.005 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 1/136 (0%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 L L V K V I A M + PEL ++I + ++G+G Sbjct: 173 LILLVTSGKLIVSGATAIALAFGMDKFLIGATVVALGTSMPELASSLIAKYRGHDEVGLG 232 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLD-WWPLTRDCLAYGITVSILICIIHDEYVQWYE 550 TI+GS +FN L + G+ A M+ P+ T L GIT +L + D ++ + Sbjct: 233 TILGSNIFNGLLIV---GVTA-MINPIQVTLRETGTALLIGITALLLTFPLSDGRIKKSQ 288 Query: 551 AFLLVSLYGVYICIMY 598 L+ LY Y+ + Sbjct: 289 GVFLIMLYAGYLIFCF 304 >UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane region; n=1; Pseudoalteromonas atlantica T6c|Rep: Sodium/calcium exchanger membrane region - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 171 Score = 42.7 bits (96), Expect = 0.008 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 3/105 (2%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD--WWPLTRDCLA 487 PELFV+V + DI +G ++G + N+L + C M++PL L RD L Sbjct: 20 PELFVSVNAALNNQPDIAIGNVIGRNIANVLLILGLC----AMIMPLTVATISLRRDALV 75 Query: 488 YGITVSILICIIHDEYV-QWYEAFLLVSLYGVYICIMYYDKPIQN 619 + S+L + E V + E L+ Y+ Y K Q+ Sbjct: 76 V-VAASVLCIALSSEGVTSFVEGLFLLGALAAYLTWTYLSKKGQS 119 >UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 precursor (Na(+)/Ca(2+)-exchange protein 6); n=2; Caenorhabditis|Rep: Putative sodium/calcium exchanger 6 precursor (Na(+)/Ca(2+)-exchange protein 6) - Caenorhabditis elegans Length = 590 Score = 42.7 bits (96), Expect = 0.008 Identities = 28/158 (17%), Positives = 68/158 (43%), Gaps = 4/158 (2%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELF---V 328 I+ + + LF+ ++ D +F P++ I L ++ V P++F Sbjct: 100 IITGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIA 159 Query: 329 NVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSI 508 +V+ + + D+ +G + G+ +F V A + + RD Y + ++ Sbjct: 160 SVLSSPTPKADLALGELFGAGLFVTTMVLAVTIFTRPFKAEV--FSSIRDIAFYLVALAF 217 Query: 509 L-ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQN 619 L C ++ ++V+ + + +Y +Y+C + + + N Sbjct: 218 LAFCFVYYDHVEIWMPITFLGVYLIYVCTVILSQILHN 255 >UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; Thermotogaceae|Rep: Na+/Ca+ antiporter, CaCA family - Thermosipho melanesiensis BI429 Length = 311 Score = 42.3 bits (95), Expect = 0.010 Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 1/118 (0%) Frame = +2 Query: 236 VEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVA 415 V K+ +L ++ PE+ V++I T E DI VG IVGS +FNIL + Sbjct: 189 VIKLAKSLGLSETFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFIL 248 Query: 416 ACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYI 586 + + V D T D + + V IL + + + E +++Y YI Sbjct: 249 GVSSLVGNLYV--DVQNFTIDLIIMNLFVFILFFTSLLRKKIGKVEGIFFLTIYVFYI 304 >UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; Bacteria|Rep: Na+/Ca+ antiporter, CaCA family - Roseiflexus sp. RS-1 Length = 367 Score = 42.3 bits (95), Expect = 0.010 Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 1/131 (0%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 LAL VV ++ V ++ V PE+ +++ E DI VG Sbjct: 187 LALLVVGSRWMVDGAVSFARVFGVSELVIGLTIVAVGTSLPEIATSIVAALRGERDIAVG 246 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAYGITVSILICIIHDEYVQWYE 550 +VGS +FN+L+V + A + + L D + + V+ L + +E Sbjct: 247 NVVGSNIFNLLSVLGLSSVVAPAGISVAPAALNFDMPVMLAVAVACLPIFFTGRLIARWE 306 Query: 551 AFLLVSLYGVY 583 +L + Y Y Sbjct: 307 GWLFLGYYIAY 317 >UniRef50_UPI00006CE59A Cluster: probable Mg2+-specific channel-like exchanger, putative; n=1; Tetrahymena thermophila SB210|Rep: probable Mg2+-specific channel-like exchanger, putative - Tetrahymena thermophila SB210 Length = 625 Score = 41.9 bits (94), Expect = 0.014 Identities = 32/155 (20%), Positives = 65/155 (41%), Gaps = 9/155 (5%) Frame = +2 Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTND----VXXXXXXXXXXXXPELFVNVIGTF 346 +IY+F + + K+F +E I + +N + + P L + Sbjct: 47 TIYVFAFIYYLSVKFFNHIIEDIVYLVNYKEEEDKEIYRPLVYCVLNSIPVLAFAMCCVI 106 Query: 347 ITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP-----LDWWPLTRDCLAYGITVSIL 511 T+ D G+ I + + NI + I + V +D W L RD + Y + +S+ Sbjct: 107 RTDYDSGIMLIFSTDMINIFLIYGLILILVILPVKKEGSDIDGWQLLRDSIWYCVGLSLF 166 Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPIQ 616 I + + V W+ +++ Y +I + Y++ I+ Sbjct: 167 IIFLFENLVTWWAGLVMICYYFSHIILQSYNETIR 201 >UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Beggiatoa sp. PS|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Beggiatoa sp. PS Length = 253 Score = 41.9 bits (94), Expect = 0.014 Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 1/168 (0%) Frame = +2 Query: 98 PAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277 P+ D+ P+ + + +H I+L L+ I L L V + V I ++ + Sbjct: 47 PSKDEKPSSVE---KNRHLHIILQ-LVFIVAGLGLLVQGSNWLVNGAIVIAQFYGISELI 102 Query: 278 XXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457 PEL +IGTF E ++ VG +VGS +FNIL V + + + + + Sbjct: 103 IALTVISIGTSLPELATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPISIDVS 162 Query: 458 WWPLTRDCLAYGITVSI-LICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 + D + I V+I + I + ++ +E L ++ Y Y ++ Sbjct: 163 QAAIFLD-MPVMIAVAIACLPIFFNNLIERWEGGLFLAYYIAYTLYLF 209 >UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=5; Bacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Pseudomonas stutzeri (strain A1501) Length = 361 Score = 41.9 bits (94), Expect = 0.014 Identities = 35/117 (29%), Positives = 48/117 (41%) Frame = +2 Query: 98 PAIDDFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277 PA DD A F + + L+ I L L L V + + AL ++ V Sbjct: 154 PAGDDEFATEFGPDESDKPFAWVFQLLLILLGLGLLVGGSNLLIEGAVGLARALGLSELV 213 Query: 278 XXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 PEL +V+ E DI VG +VGS +FN+L V +GAG V Sbjct: 214 IGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLV-----LGAGAAV 265 Score = 33.9 bits (74), Expect = 3.7 Identities = 17/45 (37%), Positives = 25/45 (55%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 PE V+V + GDI VG ++GS + NIL + + A +VV Sbjct: 53 PETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALIAPLVV 97 >UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Arabidopsis thaliana|Rep: Na/Ca,K-exchanger-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 559 Score = 41.9 bits (94), Expect = 0.014 Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 5/143 (3%) Frame = +2 Query: 182 IYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG- 358 + LF L +YF ++E + LN++ V P+LF +++ +F+ E Sbjct: 100 LLLFYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFASLV-SFMGESK 158 Query: 359 ---DIGVGTIVGSAVFNILAVAACCGIGA-GMVVPLDWWPLTRDCLAYGITVSILICIIH 526 D+G+ T+VG + F V I V ++ RD + + L I+ Sbjct: 159 GTYDVGLNTVVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCAAIGSLALILV 218 Query: 527 DEYVQWYEAFLLVSLYGVYICIM 595 + ++ A SLY VY+ + Sbjct: 219 YGKINFWGALGFCSLYAVYVAFV 241 >UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Na+/Ca+ antiporter, CaCA family - Halorubrum lacusprofundi ATCC 49239 Length = 326 Score = 41.9 bits (94), Expect = 0.014 Identities = 27/98 (27%), Positives = 44/98 (44%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL V V G+IGVG I+GS +N+ + + V+P++ + RD A Sbjct: 57 PELVVTVDAALAGLGEIGVGNIIGSNAYNLAFILG--AVSLLRVIPVERSLVHRDGAALV 114 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607 ++ + + D V E LL L+ Y + D+ Sbjct: 115 LSTLVGAAALFDRTVTGVEGALLAGLFVAYTAYLVRDE 152 Score = 33.9 bits (74), Expect = 3.7 Identities = 19/73 (26%), Positives = 33/73 (45%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 LAL +V + V A + + +++ PEL V+++ + VG Sbjct: 189 LALVLVSGHFMVEAASTLARSAGVSDWAIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVG 248 Query: 374 TIVGSAVFNILAV 412 +VGS VFN+L + Sbjct: 249 NVVGSNVFNVLGI 261 >UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=2; Marinomonas|Rep: Na+/Ca+ antiporter, CaCA family precursor - Marinomonas sp. MWYL1 Length = 332 Score = 41.5 bits (93), Expect = 0.018 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 6/168 (3%) Frame = +2 Query: 110 DFPAGLFTELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXX 289 D L L G+ V +LI + LA+ + K V I AL ++ V Sbjct: 161 DLEKDLKEGLPEDDGSSVSKSLIIALIGLAVLIGSSKLLVWGAIGIATALGVSELVIGLT 220 Query: 290 XXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPL 469 PEL +V DI +G I+GS +FN+ V + A +V D + Sbjct: 221 IVAVGTSLPELAASVSSVRKGHHDIAIGNILGSNIFNLATVLPLPALLAPGLV--DQSVI 278 Query: 470 TRDC-LAYGITVSILICII-----HDEYVQWYEAFLLVSLYGVYICIM 595 +RD G+TV++ + I + + + L++ YGVY+ I+ Sbjct: 279 SRDFPWVLGLTVALALAIFIFKKTKNNSIPRWVGLPLIASYGVYLFII 326 >UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; Rhodobacter sphaeroides|Rep: Na+/Ca+ antiporter, CaCA family - Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) Length = 305 Score = 41.5 bits (93), Expect = 0.018 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 4/138 (2%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 L + +V + V + +I + ++ V PEL + I + +I VG Sbjct: 171 LVVLMVGARLLVDSSTQIARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVG 230 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDCLAYGITVSILICIIHD--EYVQ 541 ++GS +FN+L + GI G+V+P+ R+ + + + S+L+ ++ + V Sbjct: 231 NVIGSNIFNVLGI---LGI-TGLVLPIQGLDPRFLREDMPWVLGCSLLLVLMAFALKGVP 286 Query: 542 WYEAFLLVSLYGVYICIM 595 + LL++ YG Y+ +M Sbjct: 287 RWAGALLLAAYGGYVALM 304 >UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091; n=9; Methanococcales|Rep: Uncharacterized membrane protein MJ0091 - Methanococcus jannaschii Length = 302 Score = 41.5 bits (93), Expect = 0.018 Identities = 31/133 (23%), Positives = 58/133 (43%) Frame = +2 Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367 L L L +FV E+I N++N V PE+ + +++ I Sbjct: 11 LGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGIS 70 Query: 368 VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWY 547 +G +GS + NI V I + ++V + L ++ L Y + V I +I + W Sbjct: 71 IGNAIGSCICNIGLVLGLSAIISPIIVDKN---LQKNILVYLLFV-IFAAVIGIDGFSWI 126 Query: 548 EAFLLVSLYGVYI 586 + +L+ L+ +Y+ Sbjct: 127 DGVVLLILFIIYL 139 >UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 318 Score = 41.1 bits (92), Expect = 0.024 Identities = 29/95 (30%), Positives = 49/95 (51%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL ++ + F E DI VG ++GS ++NILAV GI A ++ PL + L + Sbjct: 220 PELAISTVAAFRKESDICVGNVLGSNIYNILAV---LGITA-IIHPLQ---INTSSLQFD 272 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 + V I+ ++ + F+L GV++ + Y Sbjct: 273 MPVMIVFSLLLIPMIM--RKFILTRWEGVFLLVGY 305 >UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Silicibacter sp. TM1040|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Silicibacter sp. (strain TM1040) Length = 327 Score = 41.1 bits (92), Expect = 0.024 Identities = 30/135 (22%), Positives = 55/135 (40%) Frame = +2 Query: 194 LALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 L L VV V + + ++ V PEL +VI +GD+ G Sbjct: 192 LVLVVVGGAALVNGAVALARSFEISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFG 251 Query: 374 TIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEA 553 +VGS ++NIL + + A +P D + ++ ++ V E Sbjct: 252 NVVGSNIYNILGIGGTTALIAPSDLPGDILRFDAPVMIL-VSAGFVLFAATGFRVGRREG 310 Query: 554 FLLVSLYGVYICIMY 598 +L++ YG+YI +++ Sbjct: 311 AILLAGYGLYIWMIW 325 >UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; Methanosarcinaceae|Rep: Sodium/calcium exchanger protein - Methanosarcina acetivorans Length = 350 Score = 41.1 bits (92), Expect = 0.024 Identities = 33/144 (22%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 + ++ L A V+ KYFV L + + V PEL V V Sbjct: 208 IFTLVLSCAAIVIGAKYFVEESIFFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQG 267 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGM-VVPLDWWPLTRDCLAYGITVSILICIIHD 529 G I +G ++GS + NI + G+ + V + + T +A I++ +LI I Sbjct: 268 YGSIALGNVIGSNITNIFLILGLSGLFYPLSVAEMSLFFTTPVMIA--ISLILLIFISTG 325 Query: 530 EYVQWYEAFLLVSLYGVYICIMYY 601 ++ +E +L+ Y ++ +++Y Sbjct: 326 WEIKRWEGVVLMMFYVAFLVVLFY 349 Score = 37.9 bits (84), Expect = 0.22 Identities = 33/147 (22%), Positives = 57/147 (38%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 I ++ LI + L L V YFV + I L ++ V PEL ++ Sbjct: 2 ITVNFLI-LLLGLVFLVKGSDYFVKSASTIAKKLGVSEFVIGLTLVAIGTSIPELASSIA 60 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILIC 517 + I +G +VGS + N+ + + + M +D L RD + + Sbjct: 61 ASIQQASGIVIGNVVGSNIANVGLIVGVAALLSPMKTEIDM--LKRDGYIMLFSAVLFFV 118 Query: 518 IIHDEYVQWYEAFLLVSLYGVYICIMY 598 + + EA L V LY Y+ ++ Sbjct: 119 FAFNRELSMLEAGLFVLLYIAYVFFLF 145 >UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep: NEQ486 - Nanoarchaeum equitans Length = 308 Score = 41.1 bits (92), Expect = 0.024 Identities = 38/148 (25%), Positives = 71/148 (47%), Gaps = 4/148 (2%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 LI + LF L DK F+ + E+I +L + + + PEL V ++ Sbjct: 11 LILVSLFFLL-FGADK-FLESGERISKSLGIDDRLLGLILVSISTSLPELAVAILAALDN 68 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PL--DWWPLTRDCLAYG-ITVSILICI 520 + +I +G I+GS N+ G+G G+++ PL L + +G IT++ L+ I Sbjct: 69 KSEIVLGDIIGSNFANL-----GLGLGIGLIISPLVIKKETLFNEVPIHGAITLATLLLI 123 Query: 521 IHDEYVQWYEAFLLVSLYGVYICIMYYD 604 ++D + YEA ++ + + + +Y D Sbjct: 124 LNDSVLDKYEALTILIFFALMLLNIYKD 151 >UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteobacteria|Rep: Sodium-calcium exchanger - Vibrio fischeri (strain ATCC 700601 / ES114) Length = 323 Score = 40.7 bits (91), Expect = 0.032 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRD-CL 484 PEL +V G E D+ G I+GS VFNILAV GI A ++ P + P + RD + Sbjct: 225 PELAASVAGVLKGEDDMAAGNIIGSNVFNILAV---MGIPA-LINPSEISPDLMGRDFYV 280 Query: 485 AYGITVSILICII-HDEYVQWYEAFLLVSLYGVY 583 G+++ +LI + + E +LV+ + VY Sbjct: 281 MLGVSILLLIMALGKSRSINRIEGGILVTCFCVY 314 Score = 39.1 bits (87), Expect = 0.097 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD-WWPLTRDCLAY 490 PE+ V+ + D VG ++GS NI +A GI A ++ PL + R L Sbjct: 55 PEMMVSAAAALDGKTDTAVGNVIGS---NIANIALILGITA-LIKPLAISSAIIRRELPL 110 Query: 491 GITVSILI-CIIHDEYVQWYEAFLLVSLYGVYICIMYY 601 + V++L I+ + Y+ +YE LL+ L+ +I M Y Sbjct: 111 MLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLY 148 >UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein precursor; n=11; Proteobacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein precursor - Azotobacter vinelandii AvOP Length = 360 Score = 40.7 bits (91), Expect = 0.032 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Frame = +2 Query: 131 TELQRQ-HGAIVLHA-LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXX 304 TE R+ G + L L + L LA+ V + A + AL ++ Sbjct: 162 TEFGRKPEGRLALPGHLALVALGLAMLVWGSDLLIDATVTLARALGLSELAIGLTMVAAG 221 Query: 305 XXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412 PEL +++ E DI VG IVGS +FN+LAV Sbjct: 222 TSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAV 257 Score = 36.3 bits (80), Expect = 0.69 Identities = 22/70 (31%), Positives = 40/70 (57%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PE+ V+V +GDI VG +GS +FN+L + G+ A +V+PL ++R + + Sbjct: 53 PEMAVSVRSASGGQGDIAVGNAIGSNIFNVLMI---LGLSA-LVIPL---RVSRQLIRFD 105 Query: 494 ITVSILICII 523 + V I + ++ Sbjct: 106 VPVMIGVSLL 115 >UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger protein; n=1; Clostridium tetani|Rep: Putative sodium/calcium exchanger protein - Clostridium tetani Length = 347 Score = 40.3 bits (90), Expect = 0.042 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Frame = +2 Query: 359 DIGVGTIVGSAVFNILAVAACCGI---GAGMVVPLDWWPLTRDCLAYGITVSILICIIHD 529 D+GV TI GS VFNIL + G +++ +D + RD + Y + + L+ + Sbjct: 79 DVGVPTIAGSGVFNILIIPMATIFAYRGKDLLIKVDKKVVYRDMIFYTMAIGALVFFTYL 138 Query: 530 EYVQWYEAFLLVSLYGVYICIMY 598 + +LV +Y YI ++Y Sbjct: 139 GSYTVFAGIVLVLIYIGYIFVLY 161 >UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 305 Score = 40.3 bits (90), Expect = 0.042 Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 1/142 (0%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 L+ I F+ L D +FV + L + + + PE V++ Sbjct: 4 LLLIIGFVLLIKGAD-FFVEGSSSLARFLKIPSVIIGLTIVAMGTSAPEASVSINAALAG 62 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI-IHD 529 DI V I+GS +FN L V C +G D L RD + I +++++CI I + Sbjct: 63 NNDIAVSNIIGSNIFNGLIVVGICAFISGFKTNKD--ILKRD-MPVNILITVILCIMIAN 119 Query: 530 EYVQWYEAFLLVSLYGVYICIM 595 + E LL++ YI M Sbjct: 120 GKLSRIEGILLLAGMIFYILNM 141 >UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteobacteria|Rep: Ca2+/Na+ antiporter - Vibrio vulnificus Length = 321 Score = 39.9 bits (89), Expect = 0.056 Identities = 20/39 (51%), Positives = 24/39 (61%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PEL ++ G E D+ VG I+GS VFNILAV GI Sbjct: 222 PELAASLAGALKGEDDMAVGNIIGSNVFNILAVMGIPGI 260 >UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=8; Bacteroidales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 317 Score = 39.9 bits (89), Expect = 0.056 Identities = 28/99 (28%), Positives = 48/99 (48%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 ++L+ L+ I + LAL V + I +++ V PEL V+++ Sbjct: 1 MILNILLLI-IGLALVVGGANFLTDGAASIAKRFRLSDLVIGLTVLAFGTSAPELTVSLM 59 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL 454 DI +G ++GS +FNILA+ GI A +++PL Sbjct: 60 AALKGSADIAIGNVIGSNIFNILAIV---GITA-LIMPL 94 >UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Na+/Ca+ antiporter, CaCA family - Fervidobacterium nodosum Rt17-B1 Length = 314 Score = 39.9 bits (89), Expect = 0.056 Identities = 23/97 (23%), Positives = 46/97 (47%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 ++L L+ I F+ +++ DK V + L +++ + PEL VN++ Sbjct: 1 MILSILLLIIGFVFVSIGSDK-LVEGASTLAKKLKVSDLLIGLTIVAFGTSAPELAVNIV 59 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 + +I +G ++GS +FNIL V + ++V Sbjct: 60 SSIKGTSNISLGNVIGSNIFNILVVVGLSAVIRPVIV 96 Score = 37.1 bits (82), Expect = 0.39 Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 1/155 (0%) Frame = +2 Query: 140 QRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPE 319 ++Q G I+ +++ I LA V ++ V I A +++ + PE Sbjct: 164 EKQLGTII--SILYIIGGLAGLVFGGRWIVNGAVDIAKAFGVSDKLIGLTIVAAGTSIPE 221 Query: 320 LFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP-LTRDCLAYGI 496 L ++ +I +G VGS +FN+ + GI A ++ P+ + L D I Sbjct: 222 LATSLAAIIKGNNEIALGNAVGSNIFNVFFI---LGISA-VIKPIVYTTVLNFDVTLLVI 277 Query: 497 TVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYY 601 IL+ + ++ +E L+VS Y Y + Y Sbjct: 278 ITVILLLFSKNLKIEKFEGLLMVSTYVGYTIYLIY 312 >UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1; Loktanella vestfoldensis SKA53|Rep: Putative sodium/calcium exchanger - Loktanella vestfoldensis SKA53 Length = 305 Score = 39.9 bits (89), Expect = 0.056 Identities = 34/113 (30%), Positives = 50/113 (44%), Gaps = 2/113 (1%) Frame = +2 Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367 L L +V Y V + I ++ + PEL V+ E DI Sbjct: 168 LGLVTVMVGAHYLVQSASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMAAIRGERDIA 227 Query: 368 VGTIVGSAVFNILAVAACCGIGAGMV-VPLDWWPLTRDC-LAYGITVSILICI 520 +G IVGS +FNILA+ GI A + +P+D L D + GIT+ +L + Sbjct: 228 LGNIVGSNIFNILAI---LGITAVVTPIPVDARFLNVDTPVVIGITLLLLALV 277 >UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomonadaceae|Rep: Sodium/calcium exchanger - Oceanicaulis alexandrii HTCC2633 Length = 334 Score = 39.9 bits (89), Expect = 0.056 Identities = 31/140 (22%), Positives = 55/140 (39%), Gaps = 13/140 (9%) Frame = +2 Query: 107 DDFPAGLFTELQRQHGAIVLHALISIYLF--LALAVVCDKYFVPAVEKICHALNMTNDVX 280 DD T+++ G +++++L L + + + V I N+ + V Sbjct: 155 DDPMIAELTDIEHMDGLPAKAPMVALFLLGGLVMLPIGAQLIVDGGVGIAALFNVPDAVI 214 Query: 281 XXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMV----- 445 PEL ++ + D+ +G +VGS +FNI AV G+ A Sbjct: 215 GLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGLAASFATGQPA 274 Query: 446 ------VPLDWWPLTRDCLA 487 + LD+W +T LA Sbjct: 275 PVSDQFIQLDFWVMTAAALA 294 >UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriaceae|Rep: Cation antiporter - Halobacterium salinarium (Halobacterium halobium) Length = 318 Score = 39.9 bits (89), Expect = 0.056 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 6/97 (6%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAY- 490 PEL +V+ E D +G +VGS ++N+LAV GI A ++VP+ +T+ LA+ Sbjct: 224 PELATSVVSALRDEADFSIGNVVGSNIYNVLAV---IGIVA-ILVPI---TVTKGTLAFE 276 Query: 491 -----GITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586 G TV L + + + E +L+ YG ++ Sbjct: 277 LPVMLGFTVLALGMMAVGDRITRVEGAVLIGSYGGFV 313 >UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative Na(+)/Ca(2+) antiporter - Uncultured methanogenic archaeon RC-I Length = 308 Score = 39.9 bits (89), Expect = 0.056 Identities = 29/138 (21%), Positives = 60/138 (43%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 L+ + + +A ++ K V + + +A ++ + PE+ ++ + Sbjct: 166 LVLLAIGIACVILGGKVTVDSAVSLANAFQVSPFLIAVTIIAIGTSMPEMVTALVASRKD 225 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDE 532 EGD+ +G +GS + N L + A +V PL + + GI V +L ++ Sbjct: 226 EGDLVMGNCIGSVIVNTLFILG----AAAIVSPLPIAGVIDILILLGIIVLLLPILVTRS 281 Query: 533 YVQWYEAFLLVSLYGVYI 586 + E LLV LY +++ Sbjct: 282 QIGHREGILLVVLYVIFV 299 >UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family; n=1; Sulfurovum sp. NBC37-1|Rep: Calcium:H+/Na+ antiporter, CaCA family - Sulfurovum sp. (strain NBC37-1) Length = 310 Score = 39.5 bits (88), Expect = 0.074 Identities = 27/122 (22%), Positives = 52/122 (42%) Frame = +2 Query: 239 EKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAA 418 EKI N+ + PE+ ++ + + +I + ++GS + NI V A Sbjct: 25 EKIALKFNIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLA 84 Query: 419 CCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 + A + P + +D + V + I +I D + ++A LL+ L G Y+ + Sbjct: 85 SVFLIARNISPKRDF-FAKDSTWALVPVLVFILMILDGVISRFDAVLLLLLMGAYLLFLL 143 Query: 599 YD 604 D Sbjct: 144 QD 145 >UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; Clostridiales|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 336 Score = 39.5 bits (88), Expect = 0.074 Identities = 25/101 (24%), Positives = 44/101 (43%) Frame = +2 Query: 155 AIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNV 334 A+V+ LI ++FL +FV I L + + + PE V+V Sbjct: 11 ALVIMFLIIGFVFLIKGA---DFFVEGSSSIAKKLKVPSIIIGLTIVAMGTSLPETAVSV 67 Query: 335 IGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457 + + ++ V +VGS +FN++ V C I ++V D Sbjct: 68 TASLVHNNELAVSNVVGSNIFNLMFVIGVCAIMTPIMVQKD 108 Score = 36.3 bits (80), Expect = 0.69 Identities = 29/119 (24%), Positives = 48/119 (40%) Frame = +2 Query: 227 VPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 406 V A +I L M+ + PEL +V+ E D+ VG VGS +FNIL Sbjct: 213 VDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSVVAARKNEVDMAVGNAVGSNIFNIL 272 Query: 407 AVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVY 583 V + M + + + + G +V + D + E +V++Y +Y Sbjct: 273 MVLGIASAISPMSLISE--NVIDILVLVGFSVVVWFFARSDRKITRNEGIAMVAMYLIY 329 >UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein precursor; n=3; Gammaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family protein precursor - Psychromonas ingrahamii (strain 37) Length = 320 Score = 39.5 bits (88), Expect = 0.074 Identities = 23/84 (27%), Positives = 37/84 (44%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340 VL +I++ L L L + + + I N+ V PEL ++VI Sbjct: 171 VLWTIIAVVLGLLLLIGGSQVLLIGAIGIAEHFNVPEAVIGLTLVAIGTSLPELSISVIA 230 Query: 341 TFITEGDIGVGTIVGSAVFNILAV 412 D+ VG I+GS +FN+L + Sbjct: 231 AIRRHADVAVGNILGSNIFNLLGI 254 Score = 37.5 bits (83), Expect = 0.30 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLT-RDCLAY 490 PEL V+V + DI +G +VGS + NIL + C + + PL PL R A Sbjct: 51 PELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGICAV----ITPLAVKPLVLRRDAAT 106 Query: 491 GITVSILICII 523 + SIL I+ Sbjct: 107 VVAASILFLIL 117 >UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=2; sulfur-oxidizing symbionts|Rep: Na+/Ca+ antiporter, CaCA family precursor - Ruthia magnifica subsp. Calyptogena magnifica Length = 317 Score = 39.5 bits (88), Expect = 0.074 Identities = 25/96 (26%), Positives = 54/96 (56%), Gaps = 5/96 (5%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL V++ + + +G ++GS +FN +AV A G+ VP++ ++RD Sbjct: 221 PELAVSITSVLKKQYAMVIGNVIGSNLFNTIAVLAIPGLIHPSDVPVE--VISRD-YPVM 277 Query: 494 ITVSILICIIHDEY-----VQWYEAFLLVSLYGVYI 586 + ++IL+ I+ ++ + ++ F+L+ ++G+YI Sbjct: 278 LLLTILLFIVSYKFNKKHIINRFKGFVLIGMFGLYI 313 >UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na/Ca exchanger - Aedes aegypti (Yellowfever mosquito) Length = 583 Score = 39.5 bits (88), Expect = 0.074 Identities = 33/152 (21%), Positives = 67/152 (44%), Gaps = 3/152 (1%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 + L + I F LA D++F P + I L+++ V P+LF + Sbjct: 77 VALLTFMLILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLF-TAV 135 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PLDWW--PLTRDCLAYGITVSI 508 + ++ G ++G+ +F + VA G +V+ P + + RD + + VS Sbjct: 136 SNPNDDTELMFGELLGAGLFVVGIVA-----GTILVIRPFHVYSAAVVRDVVFFIFAVSW 190 Query: 509 LICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604 + +DE +A ++V +Y +Y+ ++ D Sbjct: 191 ITVCAYDERFTLSDAIVVVVVYVLYLVVVLID 222 >UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloarcula marismortui|Rep: Na+/Ca2+-exchanging protein - Haloarcula marismortui (Halobacterium marismortui) Length = 335 Score = 39.5 bits (88), Expect = 0.074 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 3/86 (3%) Frame = +2 Query: 188 LFLALAVVC--DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI-TEG 358 + +A AV+ YF A E++ + V PE+ VI T I E Sbjct: 11 IIVATAVIWKGSAYFERAAERLSKYYGLPVAVHGAIVVAVGSSFPEISSVVISTVIHDEF 70 Query: 359 DIGVGTIVGSAVFNILAVAACCGIGA 436 +GVG IVGSA+FN+L + A + + Sbjct: 71 SLGVGAIVGSAIFNLLVIPALAALSS 96 >UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamma proteobacterium HTCC2207|Rep: Putative Ca2+/Na+ antiporter - gamma proteobacterium HTCC2207 Length = 330 Score = 39.1 bits (87), Expect = 0.097 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 1/125 (0%) Frame = +2 Query: 152 GAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVN 331 GA L ++ + + LA A V V + + I +L ++ + PEL + Sbjct: 171 GAAALWFIVGLAVLLASAEVT----VWSAKTIAQSLGISELIIGLTVVAIGTSLPELAAS 226 Query: 332 VIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV-PLDWWPLTRDCLAYGITVSI 508 V+ DI +G + GS +FN++ V GI + M + P+ RD + I + Sbjct: 227 VVSAMRGHHDIAIGNVFGSNLFNLMLVMPAAGIISPMTISPM---VFNRDFASLAIMTLL 283 Query: 509 LICII 523 LI ++ Sbjct: 284 LIAMV 288 >UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillatoriales|Rep: Sodium-calcium exchanger - Lyngbya sp. PCC 8106 Length = 315 Score = 39.1 bits (87), Expect = 0.097 Identities = 30/139 (21%), Positives = 62/139 (44%), Gaps = 1/139 (0%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 +I + + A + + + ++ KI L + ++ PEL V + Sbjct: 173 IIVLLICTACMFLGANFTIQSIIKIADILGIGKELIAISAVALGTSLPELAVTFSASRRG 232 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICII-HD 529 + ++ +G ++GS +FN L V G+ +++P D + RD L + ++L + D Sbjct: 233 DAEVAIGNVLGSNIFNSLIVMGVPGLFEDLIIP-D--IIIRDGLPMLLASTLLFFFVTQD 289 Query: 530 EYVQWYEAFLLVSLYGVYI 586 + V +E +L LY +I Sbjct: 290 KKVTKWEGWLFFVLYAWFI 308 >UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Rep: F15I1.21 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 644 Score = 39.1 bits (87), Expect = 0.097 Identities = 45/204 (22%), Positives = 88/204 (43%), Gaps = 8/204 (3%) Frame = +2 Query: 8 SSVACVALHTTPLQNMNTSERDGYIRN---CTPPAIDDFPAGLFTELQ--RQHGAIVLHA 172 S+V+C LH ++ +++ ++++ C+P D+ + + + G I+L Sbjct: 87 STVSCSGLH----EHRGYADQCEFLKSNPICSPDGFFDYLKFFYCSCRDFKILGYILLGV 142 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI- 349 + + LF L YF ++EK+ L + V P++F + I F+ Sbjct: 143 WL-VALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS-IAAFVG 200 Query: 350 -TEGDIGVGTIVGSAVFNILAVAACCGI-GAGMVVPLDWWPLTRDCLAYGITVSILICII 523 +G++G+ +++G AVF V + A V +D RD + T+ L+ I+ Sbjct: 201 SDKGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSFFLFTLVALMVIL 260 Query: 524 HDEYVQWYEAFLLVSLYGVYICIM 595 V A VS+Y Y ++ Sbjct: 261 MVGKVTVGIAIAFVSIYVFYASLV 284 >UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=4; Pseudomonas syringae group|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Length = 343 Score = 38.7 bits (86), Expect = 0.13 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 P L ++I F E DI VG ++GS +FN+L V + A + + + + D L Sbjct: 208 PALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGVTALFAPVPLTVSPNAMVFD-LPIM 266 Query: 494 ITVSIL-ICIIHDEY-VQWYEAFLLVSLYGVY 583 + VS+L + + + Y + E L+SLY Y Sbjct: 267 LGVSLLCVPLFYSGYRIDRMEGVFLLSLYLTY 298 Score = 37.1 bits (82), Expect = 0.39 Identities = 19/70 (27%), Positives = 36/70 (51%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 P++ V++ F DI VG+++G +FN+L + C +++PL + R L Sbjct: 45 PQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLC----ALIIPL---RVARQVLHID 97 Query: 494 ITVSILICII 523 I + I C++ Sbjct: 98 IPLMIGACLL 107 >UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like protein; n=1; Salinibacter ruber DSM 13855|Rep: K+-dependent Na+/Ca+ exchanger-like protein - Salinibacter ruber (strain DSM 13855) Length = 317 Score = 38.7 bits (86), Expect = 0.13 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWP--LTRDC-L 484 PE VNV E + +G I+GS + N+ + C + V+PL P L R+ + Sbjct: 52 PEYLVNVFALISGESPLAIGNIIGSNISNVALILGACAV----VLPLAVTPEVLRREYPV 107 Query: 485 AYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMYYD 604 G+ V +C + D + + L+V L ++YD Sbjct: 108 MLGVMVLFYLCAL-DGVIGARDGVLMVVLLSGLAAYVFYD 146 Score = 35.9 bits (79), Expect = 0.91 Identities = 20/68 (29%), Positives = 31/68 (45%) Frame = +2 Query: 245 ICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424 I LN+ + V PEL +++GT E D+ VG ++GS + N+L V Sbjct: 200 ISDVLNIDHVVIGLTVVAIGTSLPELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVGTL 259 Query: 425 GIGAGMVV 448 I + V Sbjct: 260 AIAEPITV 267 >UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisphaera araneosa HTCC2155|Rep: Sodium/calcium exchanger - Lentisphaera araneosa HTCC2155 Length = 319 Score = 38.7 bits (86), Expect = 0.13 Identities = 20/77 (25%), Positives = 34/77 (44%) Frame = +2 Query: 182 IYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD 361 I+ LA FV I L ++ V PEL +++ + GD Sbjct: 176 IFAGLAGVTYGGSIFVDGASTIAAGLGVSQAVIGLTIVALGTSLPELAASIMASLKGHGD 235 Query: 362 IGVGTIVGSAVFNILAV 412 + +G ++GS +FN+LA+ Sbjct: 236 MALGNVIGSCIFNLLAI 252 >UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=3; Rhodobacterales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Stappia aggregata IAM 12614 Length = 337 Score = 38.7 bits (86), Expect = 0.13 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 5/74 (6%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP-----LDWWPLTRD 478 PEL V+ G + +G ++GS VFN+LA+ + + VP LD W + Sbjct: 238 PELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIGITAVIVPIDVPQEVLKLDIWVMLAC 297 Query: 479 CLAYGITVSILICI 520 + I + IC+ Sbjct: 298 AILLTILAGMRICL 311 >UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|Rep: Cation exchanger - Cryptosporidium hominis Length = 940 Score = 38.7 bits (86), Expect = 0.13 Identities = 30/151 (19%), Positives = 65/151 (43%), Gaps = 8/151 (5%) Frame = +2 Query: 179 SIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEG 358 S LF+A V D Y + K+ L++++ ++ + +I I E Sbjct: 109 SCILFIACGTVADTYISSLMIKLAECLSLSDTFAGSTLLAFSNAASDVILGIISVSIGEK 168 Query: 359 ---DIGVGTIVGSAVFNILAVAACCGIGA-----GMVVPLDWWPLTRDCLAYGITVSILI 514 D+ +G ++G+ +F IL V C + + + + + RD +A I + L+ Sbjct: 169 DAVDVFLGDVIGACLFIILVVFGCVMVFSKSSENSNYINIPIFNHLRDTIALTIGLIQLL 228 Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMYYDK 607 I H ++ + + + YG Y+ ++ + + Sbjct: 229 IIHHLGFISSKMSVIPLIAYGFYVLLLQWSE 259 >UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Methanoculleus marisnigri JR1|Rep: Na+/Ca+ antiporter, CaCA family - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 311 Score = 38.7 bits (86), Expect = 0.13 Identities = 30/101 (29%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL +++ EG I +G I+GS +FN+L V GI ++ P+ L + Sbjct: 215 PELATSIVAAARDEGSISIGNILGSNIFNLLLV---LGISL-LLAPVTVGSLVDIAVVVL 270 Query: 494 ITVSIL-ICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613 +V+IL + V+ + A LL+ Y YI + PI Sbjct: 271 FSVAILPLLFARPSVVRGWSALLLLG-YAAYIAWSFGAVPI 310 >UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protein; n=3; Coxiella burnetii|Rep: Sodium/calcium antiporter family protein - Coxiella burnetii Length = 322 Score = 38.3 bits (85), Expect = 0.17 Identities = 23/78 (29%), Positives = 34/78 (43%) Frame = +2 Query: 185 YLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDI 364 +L LAL + + V L +++ V PE ++G E DI Sbjct: 178 FLGLALLFISSELLVDGAVGAAQLLGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEHDI 237 Query: 365 GVGTIVGSAVFNILAVAA 418 +G I+GS +FN LAV A Sbjct: 238 AIGHIIGSNIFNSLAVLA 255 Score = 33.5 bits (73), Expect = 4.8 Identities = 22/100 (22%), Positives = 44/100 (44%) Frame = +2 Query: 158 IVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI 337 ++L ++ + + L + F+ A + L + + V PEL V+ I Sbjct: 3 VILKIIVELIVGAGLLAFGAERFITASAALARHLKIPSLVIGIILVGFGTSFPELIVSAI 62 Query: 338 GTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLD 457 F + I +G +VGS NI + G+ A +++P++ Sbjct: 63 AAFHGKTQISIGNVVGS---NIANIGLILGVVA-LIIPIE 98 >UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; Pirellula sp.|Rep: Putative uncharacterized protein - Rhodopirellula baltica Length = 339 Score = 38.3 bits (85), Expect = 0.17 Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 2/152 (1%) Frame = +2 Query: 137 LQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXP 316 L R+ IV ++ AL CD FV + L ++ V P Sbjct: 179 LGRRVAVIVWQLILLSAGVAALVFGCD-LFVDGAVSMARILGVSELVIGLTIVSAGTSLP 237 Query: 317 ELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGA--GMVVPLDWWPLTRDCLAY 490 EL +V T E I +G VGS NI+AV + A G+ V + L + Sbjct: 238 ELVTSVAATIKGERGIAIGNAVGSTTLNIVAVLGITSVIAPSGLNVADEILRLDMPLMVI 297 Query: 491 GITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586 +S ++ V+W E L++ +Y Y+ Sbjct: 298 AAMLSWILYRTGRTIVRW-EGVLMIVIYCSYV 328 >UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep: CG5685-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 950 Score = 38.3 bits (85), Expect = 0.17 Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 3/42 (7%) Frame = +2 Query: 314 PELFVNVIGTFITE---GDIGVGTIVGSAVFNILAVAACCGI 430 PE+ ++VI + + GD+G GTIVGSA +N+ + A C I Sbjct: 193 PEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMI 234 >UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1); n=185; Euteleostomi|Rep: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human) Length = 973 Score = 38.3 bits (85), Expect = 0.17 Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 3/40 (7%) Frame = +2 Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424 PE+ ++VI G T GD+G TIVGSA FN+ + A C Sbjct: 147 PEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186 >UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca exchanger; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Na/Ca exchanger - Strongylocentrotus purpuratus Length = 367 Score = 37.9 bits (84), Expect = 0.22 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 3/43 (6%) Frame = +2 Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACCGIG 433 PE+ ++VI G G +G TIVGSA FN+L + A C +G Sbjct: 105 PEILLSVIEIAGNGFQSGPLGPSTIVGSAAFNLLIITAVCIMG 147 >UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=9; Rhodobacterales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Silicibacter pomeroyi Length = 309 Score = 37.9 bits (84), Expect = 0.22 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD-CLAY 490 PEL +VI + + +I VG IVGS +FN+L + + A + V + LA Sbjct: 215 PELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILGATAVIAPIPVASRFALFDLPVALAA 274 Query: 491 GITVSILI 514 +T S+L+ Sbjct: 275 AVTFSVLL 282 >UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Desulfuromonas acetoxidans DSM 684|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Desulfuromonas acetoxidans DSM 684 Length = 314 Score = 37.9 bits (84), Expect = 0.22 Identities = 27/94 (28%), Positives = 42/94 (44%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL +++ E DI +G ++GS +FNIL V C I + V L + Sbjct: 219 PELAASLMSAAKGEMDISIGNVIGSNIFNILFVLGVCPIFQPIAVEPSILRLELPVVMLF 278 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595 + +C +W A L+VS Y ++I M Sbjct: 279 SVALVPLCWHRHVIGRWKGAVLVVS-YVLFIVAM 311 >UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=4; Firmicutes|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Clostridium perfringens (strain SM101 / Type A) Length = 331 Score = 37.9 bits (84), Expect = 0.22 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 PEL V++ DI +G ++GS +FN+LA C I A +V+ Sbjct: 50 PELAVSISAALKGSNDITMGNVLGSNLFNLLAALGCTAIVAPLVI 94 Score = 33.1 bits (72), Expect = 6.4 Identities = 21/80 (26%), Positives = 36/80 (45%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 L+SI + + ++ K V + I L ++ + PEL +++ Sbjct: 186 LLSIVGVIGI-ILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVAAKKG 244 Query: 353 EGDIGVGTIVGSAVFNILAV 412 E DI +G I+GS FNIL + Sbjct: 245 ENDIALGNILGSNTFNILLI 264 >UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; Moritella sp. PE36|Rep: Putative uncharacterized protein - Moritella sp. PE36 Length = 340 Score = 37.9 bits (84), Expect = 0.22 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 AL+ L + ++ + V ++ A+ +++ + PEL + G Sbjct: 168 ALVETIAMLFMLLISSQIMVWGSVQLAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRR 227 Query: 350 TEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCLAYGITVSILI 514 +I T++GS FN+L V A G IG G+ +P + LTRD I + ++ Sbjct: 228 GMPEIAFATVIGSNTFNLLGVLAFPGLIGDGLQLPAE--VLTRDLPMLSIMTAFMV 281 Score = 36.7 bits (81), Expect = 0.52 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 2/93 (2%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL V+ I +F + VG +GS + N V A C + +V+ + + L + Sbjct: 54 PELVVSAIASFNGAEGLAVGNAIGSNIINCGLVLALCALFMPLVIKVRFIKRELPILVFA 113 Query: 494 ITVSILICIIHDEYVQWYE--AFLLVSLYGVYI 586 + +I + + + W LL++LY VY+ Sbjct: 114 LIATIAL-MSNGSITMWDSLILILLLALYCVYL 145 >UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; Planctomyces maris DSM 8797|Rep: Sodium/calcium exchanger protein - Planctomyces maris DSM 8797 Length = 368 Score = 37.9 bits (84), Expect = 0.22 Identities = 17/42 (40%), Positives = 24/42 (57%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAG 439 PEL V+V GT +GD+ VG +GS + NI + C + G Sbjct: 74 PELMVSVTGTLAGKGDLAVGNALGSCLCNIGLIIGSCALLKG 115 >UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; Bacteroidetes|Rep: Putative uncharacterized protein - Algoriphagus sp. PR1 Length = 318 Score = 37.9 bits (84), Expect = 0.22 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 4/98 (4%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDW-WPLTRDC-LA 487 PEL +V+ + DI +G I+GS +FNI + G+ + ++ PLD+ +D + Sbjct: 220 PELATSVVASLKKNNDIAIGNIIGSNIFNIFLI---LGV-SSIINPLDYQLSFNKDLYIL 275 Query: 488 YGITVSILICII--HDEYVQWYEAFLLVSLYGVYICIM 595 G T+ + + + + + +EA +L+ Y VYI + Sbjct: 276 LGGTIFLFLAMFTGKRKSLDRWEAGILLLTYLVYIAYL 313 >UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=3; Gammaproteobacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 331 Score = 37.5 bits (83), Expect = 0.30 Identities = 18/39 (46%), Positives = 24/39 (61%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PEL +V+ DI +G I+GS +FN+LAV A GI Sbjct: 226 PELAASVMSALKGHHDIALGNIIGSNIFNLLAVMAVPGI 264 >UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Na+/Ca+ antiporter, CaCA family - Candidatus Nitrosopumilus maritimus SCM1 Length = 296 Score = 37.5 bits (83), Expect = 0.30 Identities = 18/43 (41%), Positives = 26/43 (60%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 442 PEL ++I DIGVG I+GS ++NIL + G+GA + Sbjct: 203 PELITSIIAIRKGHSDIGVGNIIGSNIYNILMI---MGVGAAL 242 >UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Prosthecochloris aestuarii DSM 271|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Prosthecochloris aestuarii DSM 271 Length = 334 Score = 37.1 bits (82), Expect = 0.39 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPL 454 PEL +++G E +I VG ++GS +FNIL V G M+ P+ Sbjct: 228 PELATSLVGAIRRESEISVGNLIGSNIFNILFVLG----GVSMIKPV 270 >UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Parvibaculum lavamentivorans DS-1|Rep: Na+/Ca+ antiporter, CaCA family - Parvibaculum lavamentivorans DS-1 Length = 350 Score = 37.1 bits (82), Expect = 0.39 Identities = 26/94 (27%), Positives = 45/94 (47%) Frame = +2 Query: 242 KICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAAC 421 +I A +++ V PEL +V+ F D+ VG I+GS + NILA+ Sbjct: 224 EIAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAI--- 280 Query: 422 CGIGAGMVVPLDWWPLTRDCLAYGITVSILICII 523 G+ A ++ PL P+ D L + + V + ++ Sbjct: 281 LGVTA-LIAPL---PIDPDFLRFHLWVMLAAVVM 310 >UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Reinekea sp. MED297|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Reinekea sp. MED297 Length = 321 Score = 37.1 bits (82), Expect = 0.39 Identities = 23/87 (26%), Positives = 37/87 (42%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 AL+ + L + +V + V I ++ V PEL +V Sbjct: 171 ALVWFAIGLGVLIVSARVLVWGAVGIADMFQISEAVIGATIIAVGTSLPELAASVASALK 230 Query: 350 TEGDIGVGTIVGSAVFNILAVAACCGI 430 DI +G ++GS +FNILAV + G+ Sbjct: 231 KHHDIAIGNVLGSNIFNILAVLSVPGL 257 >UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger protein; n=1; marine gamma proteobacterium HTCC2080|Rep: Putative sodium/calcium exchanger protein - marine gamma proteobacterium HTCC2080 Length = 321 Score = 37.1 bits (82), Expect = 0.39 Identities = 36/156 (23%), Positives = 61/156 (39%), Gaps = 8/156 (5%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340 + A+ + + L + + K V A I + ++ V PEL +++ Sbjct: 164 IAQAIGAFTVGLGVLIGSSKALVWAAVNIAESYGVSELVIGLTIIALGTSLPELAASMVS 223 Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICI 520 DI +G +VGS +FN+L V A G+ + + L L RD +T + L Sbjct: 224 AIKGHADIAIGAVVGSNMFNLLIVLAIPGLFSPL--ELSTTDLQRDLGTVFVTTAALAVF 281 Query: 521 I--------HDEYVQWYEAFLLVSLYGVYICIMYYD 604 + + L +S Y VY +YYD Sbjct: 282 VGFGWRKEKSHARLGRMAGCLFLSSYVVYCLWLYYD 317 >UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like protein; n=1; Oikopleura dioica|Rep: Sodium/calcium exchanger protein-like protein - Oikopleura dioica (Tunicate) Length = 557 Score = 37.1 bits (82), Expect = 0.39 Identities = 16/42 (38%), Positives = 28/42 (66%) Frame = +2 Query: 152 GAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDV 277 G +L++L ++LF+AL +V D +FVP + KI L ++ +V Sbjct: 73 GMNILYSLWCLWLFIALGLVADAFFVPNLTKISSQLKLSENV 114 >UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halobacteriaceae|Rep: Na+/Ca2+-exchanging protein - Halobacterium salinarium (Halobacterium halobium) Length = 344 Score = 37.1 bits (82), Expect = 0.39 Identities = 22/67 (32%), Positives = 32/67 (47%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL ++ +GVG IVGSA+FNIL V GI + + ++ Y Sbjct: 62 PELLSVLVTALDGSFGLGVGAIVGSAIFNILVVPGLAGITTTQPLDATRTVVYKEAQFYM 121 Query: 494 ITVSILI 514 + VS L+ Sbjct: 122 LAVSTLL 128 >UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria|Rep: Sodium/calcium exchanger - Shewanella oneidensis Length = 316 Score = 36.7 bits (81), Expect = 0.52 Identities = 16/39 (41%), Positives = 22/39 (56%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PEL +V+ + DI +G IVGS +FNIL + I Sbjct: 215 PELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAI 253 >UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriphagus sp. PR1|Rep: Sodium/calcium exchanger - Algoriphagus sp. PR1 Length = 312 Score = 36.7 bits (81), Expect = 0.52 Identities = 35/150 (23%), Positives = 59/150 (39%), Gaps = 1/150 (0%) Frame = +2 Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367 L L + + K V I L M+ + PEL V+V DI Sbjct: 9 LGLIILLYGGKILVDGASAIAVKLGMSAGLIGLTIVAFGTSAPELLVSVNAALKGNSDIS 68 Query: 368 VGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWY 547 VG ++GS + NI V G+ +++ L D + + + ++ ++ + Sbjct: 69 VGNVIGSNIANIGMVLGISGLFYPILIRKS--TLRFDYFITVLVTLLFYAVSYNGMIELW 126 Query: 548 EAFLLVSLY-GVYICIMYYDKPIQNFAKGS 634 E LL SL+ G + + Y Q A+GS Sbjct: 127 EGILLFSLFIGFNLYLFKYTD--QGLAEGS 154 Score = 33.5 bits (73), Expect = 4.8 Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 4/142 (2%) Frame = +2 Query: 173 LISIYLFLALAV---VCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGT 343 L++I LFL V + + V KI ++ V PEL +++ Sbjct: 169 LVAISLFLGGIVGLYIGSELLVNNAVKISREFGVSERVIGITIIAIGTSLPELITSIMAA 228 Query: 344 FITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCL-AYGITVSILICI 520 + D+ +G I+GS + N+L++ I + V ++ L D L G T+ + I Sbjct: 229 LSKKTDMAIGNILGSNIMNVLSILGITAIIKPIGVSDEF--LQSDFLWMIGFTLILFPLI 286 Query: 521 IHDEYVQWYEAFLLVSLYGVYI 586 + + E +L+ Y Y+ Sbjct: 287 RTKMRISFIEGLILLIGYCTYL 308 >UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6); n=30; Euteleostomi|Rep: Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) - Homo sapiens (Human) Length = 584 Score = 36.7 bits (81), Expect = 0.52 Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 1/145 (0%) Frame = +2 Query: 155 AIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNV 334 A+ L+ +YLFL L V K+F P + I L ++++V P++F + Sbjct: 99 AVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSAL 158 Query: 335 IG-TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSIL 511 + + + +G + G+ V VA GI P RD + Y + V + Sbjct: 159 VAFSDPHTAGLALGALFGAGVLVTTVVAG--GITILHPFMAASRPFFRDIVFYMVAVFLT 216 Query: 512 ICIIHDEYVQWYEAFLLVSLYGVYI 586 ++ V A + LY Y+ Sbjct: 217 FLMLFRGRVTLAWALGYLGLYVFYV 241 >UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/potassium ion/calcium ion; n=1; Ostreococcus lucimarinus CCE9901|Rep: CaCA family transporter: sodium ion/potassium ion/calcium ion - Ostreococcus lucimarinus CCE9901 Length = 569 Score = 36.3 bits (80), Expect = 0.69 Identities = 31/149 (20%), Positives = 62/149 (41%), Gaps = 6/149 (4%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 LI++ ALAV +FVPA+E + ++ + P+L+ V + ++ Sbjct: 140 LIAVASTYALAVAAGTFFVPALEYTATLMKISPEAAGVTLLALGNGAPDLYAQV--SELS 197 Query: 353 EG-----DIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGI-TVSILI 514 EG ++ +G+ +GS F V + V ++ L + + +++L+ Sbjct: 198 EGVLPDLNVVIGSTLGSGFFIATVVLGVVIRASPNAVVINKDALGASMGLFAVANIALLL 257 Query: 515 CIIHDEYVQWYEAFLLVSLYGVYICIMYY 601 + + WY VS Y Y C + + Sbjct: 258 AMCFGTFKMWYTMTFFVS-YATYFCFIAF 285 >UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; n=7; Caenorhabditis|Rep: Na/ca exchangers protein 2, isoform a - Caenorhabditis elegans Length = 975 Score = 36.3 bits (80), Expect = 0.69 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 20/108 (18%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFV----------------PAVEKICHALNMTND-VXXXX 289 VL+ + Y+FL +++V D++ P ++ + + + ND V Sbjct: 60 VLYFFVIAYMFLGISIVADRFMSSIEVITSMERTIVVKRPGLDPMAVQVRIWNDTVSNLT 119 Query: 290 XXXXXXXXPELFVNVIGTF---ITEGDIGVGTIVGSAVFNILAVAACC 424 PE+ +++I GD+G TIVGSA FN+ + A C Sbjct: 120 LMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAFNLFMIIAIC 167 >UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep: ENSANGP00000016911 - Anopheles gambiae str. PEST Length = 563 Score = 36.3 bits (80), Expect = 0.69 Identities = 13/33 (39%), Positives = 20/33 (60%) Frame = +2 Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424 + ++ GD+G GTIVGSA +N+ + A C Sbjct: 147 IEIVAKNFNAGDLGPGTIVGSAAYNLFVIMAIC 179 >UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).; n=1; Takifugu rubripes|Rep: Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2). - Takifugu rubripes Length = 953 Score = 35.9 bits (79), Expect = 0.91 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%) Frame = +2 Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424 PE+ ++VI G G++G GTIVGSA FN+ + C Sbjct: 93 PEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLC 132 >UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=9; Bacteroidetes|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Flavobacteria bacterium BBFL7 Length = 317 Score = 35.9 bits (79), Expect = 0.91 Identities = 27/135 (20%), Positives = 58/135 (42%), Gaps = 1/135 (0%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 +L + + L L V+ ++ V + + L ++ + PEL V++ Sbjct: 2 SLFYLLIGLVLLVIGGEFLVRSSVGLSLKLRLSRMIIGLTVVSFATSAPELIVSIQSALD 61 Query: 350 TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRD-CLAYGITVSILICIIH 526 + +G ++GS + NI V + A + + D++ +A+ I + IL+ + Sbjct: 62 GFSGLAIGNVIGSNIANIALVLGATALIAPLAIDKDFFKFNWPWMMAFSILLYILL-LSD 120 Query: 527 DEYVQWYEAFLLVSL 571 + V+W LL S+ Sbjct: 121 NNLVRWEGGILLGSI 135 Score = 33.5 bits (73), Expect = 4.8 Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 8/147 (5%) Frame = +2 Query: 182 IYLFLALAVVC----DKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 I++FLAL + + V I +L + + PEL ++I Sbjct: 167 IFMFLALGGLALWQGSELLVKGAVDIAASLGIPESIIAVSMVALGTSVPELAASIIAALK 226 Query: 350 TEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCL-AYGITVSIL-ICI 520 E I +G ++GS +FNI +V I + P L D GI+ ++L + Sbjct: 227 KEKAISLGNLIGSNIFNIGSVLGITALIQPIQIQPEGMGLLNNDIFWMLGISFALLPLAF 286 Query: 521 IHDEY-VQWYEAFLLVSLYGVYICIMY 598 + Y + Y+ L ++ Y ++I + + Sbjct: 287 LPKVYHISRYKGILFLAAYLLFIYLAF 313 >UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Hyphomonas neptunium (strain ATCC 15444) Length = 339 Score = 35.9 bits (79), Expect = 0.91 Identities = 13/33 (39%), Positives = 22/33 (66%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412 PEL +V+ F + D+ +G ++GS +FNIL + Sbjct: 220 PELATSVVAAFRKKADVALGNVIGSNLFNILGI 252 >UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=2; Psychrobacter|Rep: Na+/Ca+ antiporter, CaCA family precursor - Psychrobacter sp. PRwf-1 Length = 322 Score = 35.9 bits (79), Expect = 0.91 Identities = 24/70 (34%), Positives = 37/70 (52%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL +V E D+ +G ++GS +FN L V I M +D L+RD + G Sbjct: 220 PELVASVAAARRGEHDMALGNVIGSNLFNTLGVVGLAAIIKPM-QHIDPQILSRDVMMVG 278 Query: 494 ITVSILICII 523 + VS+L+ I+ Sbjct: 279 M-VSVLLFIL 287 >UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr6 scaffold_15, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 562 Score = 35.9 bits (79), Expect = 0.91 Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 2/148 (1%) Frame = +2 Query: 149 HGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFV 328 + A++L L+ YL L YF ++E + L ++ ++ P+LF Sbjct: 121 YSALILWLLVLFYL---LGNTAANYFCCSLEGLSRILKLSPNIAGVTLLSLGNGAPDLFA 177 Query: 329 NVIGTFITEGD-IGVGTIVGSAVFNILAVAACCGIGAGMVVP-LDWWPLTRDCLAYGITV 502 +++ E + +G+ +I+G A F V I P ++ D + +++ Sbjct: 178 SIVSFMGDETEKVGLNSILGGAFFVSSIVVGIISISVCHSRPSIERSSFIWDVTFFLLSL 237 Query: 503 SILICIIHDEYVQWYEAFLLVSLYGVYI 586 + L+ II + + A SLY +Y+ Sbjct: 238 ACLLVIIMLGKINLWGAISFFSLYFIYV 265 >UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family transporter precursor; n=1; Thiomicrospira crunogena XCL-2|Rep: Ca2+:cation antiporter (CaCA) family transporter precursor - Thiomicrospira crunogena (strain XCL-2) Length = 329 Score = 35.5 bits (78), Expect = 1.2 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 4/148 (2%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 AL+ + L L + ++ K V +I ++ + PEL + Sbjct: 179 ALVFLILGLVVLMISAKMMVWGAVEIAEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKK 238 Query: 350 TEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDC-LAYGITVSILICIIH 526 E D+ +G I+GS +FN+LAV + + A V+ D L D + +T+++L+ + Sbjct: 239 GEADLMIGNILGSNLFNLLAVMSMPALIAPSVI--DNATLLLDYPIMLALTLAMLLVALP 296 Query: 527 DE---YVQWYEAFLLVSLYGVYICIMYY 601 + + E ++L+ + Y+ ++Y+ Sbjct: 297 RKGKAVITKTEGYILLISFIGYMLLLYF 324 >UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein; n=1; Plesiocystis pacifica SIR-1|Rep: K+-dependent Na+/Ca+ exchanger protein - Plesiocystis pacifica SIR-1 Length = 325 Score = 35.5 bits (78), Expect = 1.2 Identities = 27/89 (30%), Positives = 38/89 (42%) Frame = +2 Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIG 367 L LAL V + V + L ++ V PEL V+ E DI Sbjct: 10 LGLALLVAGGEALVRGATSLAQLLRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIA 69 Query: 368 VGTIVGSAVFNILAVAACCGIGAGMVVPL 454 + ++GS +FNI AA G+ A +V PL Sbjct: 70 LANVIGSNIFNI---AAIVGV-AALVAPL 94 >UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein precursor; n=5; Proteobacteria|Rep: Na+/Ca+ antiporter, CaCA family protein precursor - Psychromonas ingrahamii (strain 37) Length = 326 Score = 35.5 bits (78), Expect = 1.2 Identities = 17/39 (43%), Positives = 22/39 (56%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PEL + E D+ VG I+GS +FNIL V A G+ Sbjct: 223 PELAATIAAARKKEFDLAVGNIIGSNIFNILGVMALPGL 261 >UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorhabditis|Rep: Sodium-calcium exchanger - Caenorhabditis elegans Length = 880 Score = 35.5 bits (78), Expect = 1.2 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 3/40 (7%) Frame = +2 Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424 PE+ ++VI G G++G TIVGSA FN+ + A C Sbjct: 143 PEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVC 182 >UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; Methanosarcina mazei|Rep: Sodium-calcium exchanger protein - Methanosarcina mazei (Methanosarcina frisia) Length = 392 Score = 35.5 bits (78), Expect = 1.2 Identities = 23/94 (24%), Positives = 44/94 (46%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PE ++ +F I +G ++GS + NI + + + + V + L RD Sbjct: 53 PEFASSLTASFEQASGIVIGNVLGSNIANIGLIVSTAALLSN--VKTEELMLRRDGYIML 110 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICIM 595 +V + + + D + +EAF+ + LY VYI + Sbjct: 111 FSVFLFLLFVVDFRISRFEAFIFLLLYFVYILFL 144 >UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31; Coelomata|Rep: Sodium-calcium exchanger - Gallus gallus (Chicken) Length = 254 Score = 35.1 bits (77), Expect = 1.6 Identities = 15/33 (45%), Positives = 19/33 (57%) Frame = +2 Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424 + V G GD+G TIVGSA FN+ + A C Sbjct: 55 IEVCGHGFVAGDLGPSTIVGSAAFNMFIIIAIC 87 >UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomonas neptunium ATCC 15444|Rep: Sodium/calcium exchanger - Hyphomonas neptunium (strain ATCC 15444) Length = 329 Score = 35.1 bits (77), Expect = 1.6 Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 1/99 (1%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340 V A+ + L +A + + + E + L + ++ PE+ + Sbjct: 171 VWRAIFYVPLGIAGLLYASRMIITGGEGVARELGVPDEWIGLTILALGTSLPEIGAGLAA 230 Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGI-GAGMVVPL 454 F GD+ G I+GS VFNIL + G V PL Sbjct: 231 AFRQRGDVVAGNILGSNVFNILGAGGIVALFGPFEVAPL 269 >UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Na+/Ca+ antiporter, CaCA family precursor - Alkalilimnicola ehrlichei (strain MLHE-1) Length = 327 Score = 35.1 bits (77), Expect = 1.6 Identities = 21/81 (25%), Positives = 36/81 (44%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 AL+ + L L + ++ + V A + + V PEL + Sbjct: 177 ALLWLLLGLVVLLISAQTAVWAATGLAERAGVAETVVGLTLVAVGTSLPELATCLAAARR 236 Query: 350 TEGDIGVGTIVGSAVFNILAV 412 ++GDI +G I+GS +FN+L V Sbjct: 237 SQGDIAIGNIIGSNIFNLLGV 257 >UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 737 Score = 35.1 bits (77), Expect = 1.6 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 11/106 (10%) Frame = +2 Query: 314 PELFVNVIGTFITEG----DIGVGTIVGSAVFNILAVAACCGIG-----AGMVVPLDWWP 466 PE+ +++I I G +G TIVGSA FN+L + C + + ++ + Sbjct: 111 PEILLSIIEITIMNGFEAGALGPSTIVGSAAFNLLCITGVCVMAVPKFETRRIKSMNVFA 170 Query: 467 LT--RDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 +T LAY I + I++ + + V+ +EA L + + + I Y Sbjct: 171 VTAITSLLAY-IWLFIILSVNTKDVVELWEAILTFLFFPILVIIAY 215 >UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum symbiosum|Rep: Ca2 /Na antiporter - Cenarchaeum symbiosum Length = 294 Score = 35.1 bits (77), Expect = 1.6 Identities = 17/45 (37%), Positives = 25/45 (55%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 PEL +V+ DIGVG I+GS ++NIL + + A + V Sbjct: 201 PELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGVASMIAAVPV 245 >UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH0465 protein - Bacillus halodurans Length = 318 Score = 34.7 bits (76), Expect = 2.1 Identities = 20/91 (21%), Positives = 38/91 (41%) Frame = +2 Query: 176 ISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITE 355 + + L AL + +FV I LN++ + PE ++I Sbjct: 4 VLLLLGFALLIKGADFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNGN 63 Query: 356 GDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 D+ +G ++GS +FNI V + + ++V Sbjct: 64 PDVALGNVIGSNMFNITLVVGLTALLSPLIV 94 Score = 33.9 bits (74), Expect = 3.7 Identities = 27/91 (29%), Positives = 40/91 (43%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL ++ E +I +G IVGS++FNI V M V D + L Sbjct: 223 PELVTSLTAALKKESEIALGNIVGSSIFNIFFVLGTAATITPMHV--DSRVVVDLLLLIF 280 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYI 586 +T+ +L+ V YE +L S Y Y+ Sbjct: 281 LTLLLLVFSRTRYTVGKYEGLILASFYIGYM 311 >UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=2; Chloroflexus|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Chloroflexus aurantiacus J-10-fl Length = 361 Score = 34.7 bits (76), Expect = 2.1 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PE+ V++ F +G I +G IVGS + N++ + + + P+D RD L Sbjct: 50 PEIAVSLQAAFDGQGAITLGNIVGSNIANVMLILGVAAMFGSL--PVDQQIFRRD-LPIM 106 Query: 494 ITVSILICIIH-DEYVQWYEAFLLVSLYGVYICIMY 598 I S+L ++ D + W + +++ Y IM+ Sbjct: 107 IGASLLTFLLALDRTLSWVDGMIMLLALTGYGWIMW 142 Score = 33.1 bits (72), Expect = 6.4 Identities = 24/91 (26%), Positives = 38/91 (41%) Frame = +2 Query: 140 QRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPE 319 QR AIVL L + L L ++ ++ V ++ + PE Sbjct: 158 QRHWRAIVLQ-LAMVVGGLVLLILGARWLVDGAVTFASWFGVSELIIGLTIVAVGTSLPE 216 Query: 320 LFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412 + +VI E DI VG ++GS + N+L V Sbjct: 217 IATSVIAGLRGERDIAVGNVIGSNILNLLLV 247 >UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antiporter; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable sodium/calcium exchanger antiporter - Psychroflexus torquis ATCC 700755 Length = 158 Score = 34.7 bits (76), Expect = 2.1 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 9/104 (8%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIG----VGTIVGSAVFNILAVAACCGIGA-----GMVVPLDWWP 466 PELF+ + F + +G +GT GS +FN L + + +G V + Sbjct: 53 PELFIALFFLFFLKDVVGFSGGLGTSFGSVLFNSLIIPSAAVLGVLSKTNKKSVSVSRKI 112 Query: 467 LTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 + RD +LI I + W E+ +L+++Y +Y+ ++ Sbjct: 113 ILRDGFWLLFVEFMLIYFIQQGEISWIESSVLITIYVLYVMYLF 156 >UniRef50_A2Q2A6 Cluster: Zinc finger, RING-type; Transcription factor jumonji, jmjC; Zinc finger, C2H2-type; n=1; Medicago truncatula|Rep: Zinc finger, RING-type; Transcription factor jumonji, jmjC; Zinc finger, C2H2-type - Medicago truncatula (Barrel medic) Length = 1183 Score = 34.7 bits (76), Expect = 2.1 Identities = 24/71 (33%), Positives = 33/71 (46%) Frame = +3 Query: 15 LPASRSIQRHFKI*TPPNEMAISGTALRLLSMTSLLDSSRSCNDSTELSYCTRSSPSIFF 194 LP + K+ PP E+ T L L+ TS+L +CNDS ++S Sbjct: 575 LPDMTNCNDSKKVSCPPTELGGRDTGLLDLTTTSMLPEMTNCNDSKKVSCPPTELDGRDT 634 Query: 195 *LLQLFATNTL 227 LL L AT+TL Sbjct: 635 GLLDLTATSTL 645 >UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Enterobacteriaceae|Rep: Inner membrane protein yrbG - Escherichia coli (strain K12) Length = 325 Score = 34.7 bits (76), Expect = 2.1 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCG-IGAGMVVPLDWWPLTRDCLAY 490 PEL + G E DI VG I+G+ +FNI+ V I G + PL + +RD + Sbjct: 223 PELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAY---SRD-YSV 278 Query: 491 GITVSI---LICIIHDEYVQWYEAFLLVSLYGVYICIMYYDKPI 613 + VSI L+C LL + V++ ++Y+ PI Sbjct: 279 MLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPI 322 >UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF10698, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 793 Score = 34.3 bits (75), Expect = 2.8 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Frame = +2 Query: 230 PAVEKICHALNMTND-VXXXXXXXXXXXXPELFVNVI---GTFITEGDIGVGTIVGSAVF 397 P EKI + + N+ V PE+ ++V+ G G++G TIVGSA F Sbjct: 54 PGGEKISTRVRVWNETVSNLTLMALGSSAPEILLSVVEVCGHNFNAGELGPNTIVGSAAF 113 Query: 398 NILAVAACC 424 N+ + C Sbjct: 114 NMFVIIGLC 122 >UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Eubacterium ventriosum ATCC 27560 Length = 339 Score = 34.3 bits (75), Expect = 2.8 Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 2/132 (1%) Frame = +2 Query: 197 ALAV-VCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVG 373 A+A+ V + V + + + A M+ + PEL + + E D+ +G Sbjct: 201 AIAIAVGGQVVVDSAKSLALAAGMSETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIG 260 Query: 374 TIVGSAVFNILAV-AACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYE 550 +VGS + NIL V I + V +++ + ++ T+ + I ++ E Sbjct: 261 NVVGSNISNILLVLGLSAAISSVGVTAMNFVDI---IVSLAATIIVFIVASTQRTIKKKE 317 Query: 551 AFLLVSLYGVYI 586 LV +Y Y+ Sbjct: 318 GIFLVIIYAFYM 329 Score = 33.1 bits (72), Expect = 6.4 Identities = 24/96 (25%), Positives = 39/96 (40%) Frame = +2 Query: 161 VLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIG 340 +L ++ + F+ L D YFV + L + + V PEL V+ Sbjct: 4 ILDIILLLVGFVLLIKGAD-YFVDGSCAVAKRLRVPSIVIGLTIVAVGTSLPELAVSTFA 62 Query: 341 TFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 I +G +VGS +FN+L V + M+V Sbjct: 63 AVKHSNAIALGNVVGSNIFNLLMVIGITALFKDMLV 98 >UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF13621, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 964 Score = 33.9 bits (74), Expect = 3.7 Identities = 15/31 (48%), Positives = 18/31 (58%) Frame = +2 Query: 332 VIGTFITEGDIGVGTIVGSAVFNILAVAACC 424 V G G +G GTIVGSA FN+L + C Sbjct: 118 VCGHGFAAGALGPGTIVGSAAFNMLVIVGVC 148 >UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacteria|Rep: Na+/Ca2+-exchanging protein - Salinibacter ruber (strain DSM 13855) Length = 350 Score = 33.9 bits (74), Expect = 3.7 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%) Frame = +2 Query: 314 PELFVNVIGTFIT-EGDIGVGTIVGSAVFNILAVAACCGIGA 436 PEL V+ + + ++GV +VGSA+FNIL + A G+ A Sbjct: 58 PELSTAVLSAALHGDFELGVAAVVGSALFNILMIPALAGLWA 99 >UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family - Dinoroseobacter shibae DFL 12 Length = 321 Score = 33.9 bits (74), Expect = 3.7 Identities = 13/33 (39%), Positives = 21/33 (63%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412 PEL V+ + D+ +G ++GS +FNILA+ Sbjct: 222 PELATAVVAAIKRQSDVVLGNVIGSNIFNILAI 254 >UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3; Tetrahymena thermophila|Rep: Cation-exchanger protein 1 - Tetrahymena thermophila Length = 594 Score = 33.9 bits (74), Expect = 3.7 Identities = 36/180 (20%), Positives = 74/180 (41%), Gaps = 5/180 (2%) Frame = +2 Query: 83 RNCTPPAIDDFPAGLFTELQRQHGAI-VLHALISIYLFLALAVVCDKYFVPAVEKICHAL 259 +NC + F F ++++ + +L LI +Y F L+ + + Y PA+ K+ Sbjct: 26 QNCNVEQLVKFSYFYFCQVKQSIIVLDLLTILIPLYAFRMLSQISEYYLSPALAKVSKCF 85 Query: 260 NMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD---IGVGTIVGSAVFNILAVAACCGI 430 ++ V P++ ++ + GD I VG+I G+ +F Sbjct: 86 KLSQSVAGVTLLALGNGGPDVATAIVAG-SSGGDSITIAVGSIFGAGLFVTTYTLQNVIQ 144 Query: 431 GAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFLLVSLYGVYI-CIMYYDK 607 AG + + RD + Y I ++ + A +S+YG+++ ++Y D+ Sbjct: 145 NAGS-IHIKSKTFVRDMVFYLIGCCVVFIYTIVGSINLGMAIGFMSIYGLFLFTVIYQDR 203 >UniRef50_Q6CTM9 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome C of strain NRRL Y- 1140 of Kluyveromyces lactis; n=2; Saccharomycetaceae|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome C of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 380 Score = 33.9 bits (74), Expect = 3.7 Identities = 20/83 (24%), Positives = 39/83 (46%) Frame = -3 Query: 265 HVKRMTNFFNSRYKVFVANNCKS*KKIDGDERVQYDSSVLSLQLREESSREVIDSRRSAV 86 H + + FNS+ + N ID D+++ ++ V+ +++ + + IDS + Sbjct: 28 HDQVLPILFNSKLDTSILNKIWFLADIDDDDQLDFEEFVICMRMIFDMVNKNIDSVPDEL 87 Query: 85 PDIAISFGGVHILKWRCMERDAG 17 PD I ++K R ER +G Sbjct: 88 PDWLIPGSKAELVKQRKTERSSG 110 >UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; Methanosarcina|Rep: Sodium/calcium exchanger protein - Methanosarcina acetivorans Length = 418 Score = 33.9 bits (74), Expect = 3.7 Identities = 22/100 (22%), Positives = 39/100 (39%) Frame = +2 Query: 131 TELQRQHGAIVLHALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXX 310 +E++ + +L LI + + VV KYF+ L + + Sbjct: 261 SEIKNPSESSLLKELIKLIVSGIAIVVGAKYFIEQSIFFALLLEIPETLIGISLVAIGTS 320 Query: 311 XPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PEL V + I +G ++GS + N L + C G+ Sbjct: 321 LPELMVTISAARSGYASIALGNVIGSNITNTLLILGCSGL 360 >UniRef50_P13983 Cluster: Extensin precursor; n=1; Nicotiana tabacum|Rep: Extensin precursor - Nicotiana tabacum (Common tobacco) Length = 620 Score = 33.9 bits (74), Expect = 3.7 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Frame = -2 Query: 494 SHKPDNL**EATSPKEQPFPHQYHNKPPQLIY*RQPNPLWS--PLRYHPP 351 +H+P L SP+ QP P Y PP QP+P +S P Y PP Sbjct: 243 THQPSPLRHLPPSPRRQPQPPTYSPPPPAYAQSPQPSPTYSPPPPTYSPP 292 >UniRef50_UPI00006CC43D Cluster: Major Facilitator Superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Major Facilitator Superfamily protein - Tetrahymena thermophila SB210 Length = 586 Score = 33.5 bits (73), Expect = 4.8 Identities = 18/73 (24%), Positives = 30/73 (41%) Frame = +2 Query: 380 VGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFL 559 +GS +F + VA CG+ GM C + S+ I ++ V W + Sbjct: 63 LGSGIFPFMMVAVACGVPVGMKAIKYVGSARLVCYVCSLIASLCILLVSYAKVFWLFVII 122 Query: 560 LVSLYGVYICIMY 598 ++G + IMY Sbjct: 123 YGIIFGFFTGIMY 135 >UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).; n=1; Takifugu rubripes|Rep: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1). - Takifugu rubripes Length = 900 Score = 33.5 bits (73), Expect = 4.8 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Frame = +2 Query: 230 PAVEKICHALNMTND-VXXXXXXXXXXXXPELFVNVI---GTFITEGDIGVGTIVGSAVF 397 P EKI + + N+ V PE+ ++V+ G G++G TIVGSA F Sbjct: 105 PNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAF 164 Query: 398 NILAVAACC 424 N+ + C Sbjct: 165 NMFVIIGLC 173 >UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14779, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 880 Score = 33.5 bits (73), Expect = 4.8 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Frame = +2 Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424 PE+ ++VI G G +G TIVGSA FN+ + A C Sbjct: 90 PEILLSVIEVCGHNFESGALGPSTIVGSAAFNMFVIIAIC 129 >UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=17; Rhodobacterales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Silicibacter pomeroyi Length = 319 Score = 33.5 bits (73), Expect = 4.8 Identities = 12/33 (36%), Positives = 21/33 (63%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAV 412 PEL V+ + D+ +G ++GS +FN+LA+ Sbjct: 225 PELATTVMAALRRQADVALGNVIGSNMFNLLAI 257 >UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family; n=3; Epsilonproteobacteria|Rep: Calcium:H+/Na+ antiporter, CaCA family - Nitratiruptor sp. (strain SB155-2) Length = 308 Score = 33.5 bits (73), Expect = 4.8 Identities = 29/138 (21%), Positives = 54/138 (39%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFIT 352 LI + + + V + V + I +L ++ + PEL V+++ Sbjct: 168 LILLLVGFVMVVYGADFAVESASHIARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMND 227 Query: 353 EGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDE 532 + D+ +G I+GS V N V + + V + + D L I +LI I Sbjct: 228 KADMSIGNIIGSNVANFSVVLGSAALVNPLHVNMHTYAF--DILTAIIASVMLIFITATR 285 Query: 533 YVQWYEAFLLVSLYGVYI 586 +L++ GV+I Sbjct: 286 LYNKSAGIVLLATLGVFI 303 >UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 320 Score = 33.5 bits (73), Expect = 4.8 Identities = 22/81 (27%), Positives = 37/81 (45%) Frame = +2 Query: 170 ALISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFI 349 A + + + LAL + + V +I L +++ V PEL +V Sbjct: 168 ATLWLLVGLALLMGSSRGVVWGASEIASTLGVSDLVIGLTVVAIGTSLPELAASVASALR 227 Query: 350 TEGDIGVGTIVGSAVFNILAV 412 E + +G ++GS VFN+LAV Sbjct: 228 GEDAMAIGNVLGSNVFNLLAV 248 >UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Marinobacter sp. ELB17|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Marinobacter sp. ELB17 Length = 328 Score = 33.5 bits (73), Expect = 4.8 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVV 448 PEL +V + D+ +G IVGS +FNIL+V A + +V+ Sbjct: 222 PELTASVAAARKGQSDMIIGGIVGSNIFNILSVMAITAVVKPLVI 266 >UniRef50_Q5ZC54 Cluster: Putative uncharacterized protein P0443D08.40; n=1; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein P0443D08.40 - Oryza sativa subsp. japonica (Rice) Length = 335 Score = 33.5 bits (73), Expect = 4.8 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Frame = +2 Query: 455 DWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFL-LVSLYGVYICIMYYDKPIQNFAKG 631 D W R+ AYGI V I++ D VQ+Y +L + LYG Y+ +P + G Sbjct: 63 DLWDGFRESSAYGIAVPIVLNGCSDGVVQYYVPYLSAIQLYGRLRRHFYHSRPSGEDSDG 122 Query: 632 SW 637 + Sbjct: 123 DY 124 >UniRef50_A2WKF8 Cluster: Putative uncharacterized protein; n=2; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 286 Score = 33.5 bits (73), Expect = 4.8 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Frame = +2 Query: 455 DWWPLTRDCLAYGITVSILICIIHDEYVQWYEAFL-LVSLYGVYICIMYYDKPIQNFAKG 631 D W R+ AYGI V I++ D VQ+Y +L + LYG Y+ +P + G Sbjct: 63 DLWDGFRESSAYGIAVPIVLNGCSDGVVQYYVPYLSAIQLYGRLRRHFYHSRPSGEDSDG 122 Query: 632 SW 637 + Sbjct: 123 DY 124 >UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_89, whole genome shotgun sequence - Paramecium tetraurelia Length = 553 Score = 33.5 bits (73), Expect = 4.8 Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 2/138 (1%) Frame = +2 Query: 188 LFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGD-- 361 +F L+ + Y PAV I ++ + P++ +I T + Sbjct: 66 MFNLLSKTAENYLSPAVAHIAKYFKLSQTLSGITLIALANGAPDVITAIIATGEDDQGVL 125 Query: 362 IGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVSILICIIHDEYVQ 541 I VG+I GS +F V + ++ ++ LTRD + + + +I + Y+ Sbjct: 126 IAVGSIFGSGLFMTTFVLGSVLYYSKHIL-VNKVSLTRDLIFNILGIGSIITFGYIGYIS 184 Query: 542 WYEAFLLVSLYGVYICIM 595 + L VSLY +YI ++ Sbjct: 185 NQFSILFVSLYIMYIFVV 202 >UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome shotgun sequence; n=10; Clupeocephala|Rep: Chromosome 10 SCAF15123, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1007 Score = 33.1 bits (72), Expect = 6.4 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Frame = +2 Query: 314 PELFVNVI---GTFITEGDIGVGTIVGSAVFNILAVAACC 424 PE+ ++VI G G++G TIVGSA FN+ + C Sbjct: 110 PEILLSVIEVCGHDFKPGELGPATIVGSAAFNMFVIIGLC 149 >UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Parvularcula bermudensis HTCC2503|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Parvularcula bermudensis HTCC2503 Length = 327 Score = 33.1 bits (72), Expect = 6.4 Identities = 14/39 (35%), Positives = 20/39 (51%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGI 430 PEL + E + VG ++GS +FNIL V G+ Sbjct: 223 PELATVIAAARKAEASVAVGNVIGSNIFNILFVGGAMGV 261 >UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, expressed; n=6; Magnoliophyta|Rep: Magnesium/proton exchanger, putative, expressed - Oryza sativa subsp. japonica (Rice) Length = 523 Score = 33.1 bits (72), Expect = 6.4 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 7/91 (7%) Frame = +2 Query: 347 ITEGDIGVGTIVGSAVFNILAVAACCGI--GAG---MVVPLDWW--PLTRDCLAYGITVS 505 +T G +G GT+VGSA F++ + A C + AG + L W L AY I + Sbjct: 117 LTAGGLGPGTLVGSAAFDLFPIHAVCVVMPRAGSKKKISDLGVWLVELFWSFWAY-IWLY 175 Query: 506 ILICIIHDEYVQWYEAFLLVSLYGVYICIMY 598 I++ + + +EA L V YG+ + Y Sbjct: 176 IILEVWTPRVITLWEALLTVLQYGLLLLHAY 206 >UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3); n=109; Eumetazoa|Rep: Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3) - Homo sapiens (Human) Length = 927 Score = 33.1 bits (72), Expect = 6.4 Identities = 14/33 (42%), Positives = 18/33 (54%) Frame = +2 Query: 326 VNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424 + V G GD+G TIVGSA FN+ + C Sbjct: 153 IEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185 >UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; Aquifex aeolicus|Rep: Putative uncharacterized protein - Aquifex aeolicus Length = 322 Score = 32.7 bits (71), Expect = 8.4 Identities = 17/69 (24%), Positives = 28/69 (40%) Frame = +2 Query: 245 ICHALNMTNDVXXXXXXXXXXXXPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACC 424 + AL ++ V PELF + + + DI +G + GS +FN V Sbjct: 199 LAKALGVSEAVIGLFVVAIGTSLPELFASAVSAYKGNPDIALGNVAGSNIFNATLVLGTS 258 Query: 425 GIGAGMVVP 451 + + VP Sbjct: 259 SVIRDIPVP 267 >UniRef50_Q1ARL7 Cluster: Sodium/calcium exchanger membrane region precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Sodium/calcium exchanger membrane region precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 338 Score = 32.7 bits (71), Expect = 8.4 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Frame = +2 Query: 173 LISIYLFLALAVVCDKYFVPAVEKICHALNMTNDVXXXXXXXXXXXXPELFVNVI---GT 343 ++ + L L ++ F AVE + LNM PE + ++ G Sbjct: 3 IVELILSLGAILLAAFLFTNAVEILGERLNMGQGAVGSVLAAVGTALPETMIPIVAILGA 62 Query: 344 FI------TEGDIGVGTIVGSAVFNILAVAACCGIGA 436 I T G+IGVG I+G+ +LA A C IGA Sbjct: 63 LILGRDPQTAGEIGVGAILGAPF--LLATLAMCVIGA 97 >UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Alkaliphilus metalliredigens QYMF|Rep: Na+/Ca+ antiporter, CaCA family - Alkaliphilus metalliredigens QYMF Length = 334 Score = 32.7 bits (71), Expect = 8.4 Identities = 21/93 (22%), Positives = 44/93 (47%) Frame = +2 Query: 314 PELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYG 493 PEL V+VI T D+ +G ++GS + N+ + + + + + + + R G Sbjct: 54 PELLVSVIATQQHYYDVAIGNVIGSMICNVGLILGLTTLFSPIKLNRSGFAI-RGFFMLG 112 Query: 494 ITVSILICIIHDEYVQWYEAFLLVSLYGVYICI 592 T ++++ + D + E + L+ +YI I Sbjct: 113 ST-ALMLFFLRDRMISPREGTWFIVLFTIYILI 144 >UniRef50_Q8ILY2 Cluster: Putative uncharacterized protein; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein - Plasmodium falciparum (isolate 3D7) Length = 551 Score = 32.7 bits (71), Expect = 8.4 Identities = 18/64 (28%), Positives = 31/64 (48%) Frame = -3 Query: 400 IEDSRTHYGPHSDITLRNEGTYDVHE*FWCRSSCGHESRSSHIVCHVKRMTNFFNSRYKV 221 I +S+++Y P I+ N D H + H SRS+ + K + N FN++ ++ Sbjct: 376 INNSQSNYIPSIHISSLNCNEIDPHNKYISTKGAIHNSRSNLLTNQTKNIQNDFNNKTQM 435 Query: 220 FVAN 209 F N Sbjct: 436 FKEN 439 >UniRef50_A0BCS6 Cluster: Chromosome undetermined scaffold_10, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_10, whole genome shotgun sequence - Paramecium tetraurelia Length = 582 Score = 32.7 bits (71), Expect = 8.4 Identities = 14/29 (48%), Positives = 17/29 (58%) Frame = -2 Query: 437 PHQYHNKPPQLIY*RQPNPLWSPLRYHPP 351 P Q +PPQ+IY + P PL P Y PP Sbjct: 155 PQQPIIQPPQIIYQQMPQPLQQPQYYPPP 183 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 695,795,657 Number of Sequences: 1657284 Number of extensions: 13975643 Number of successful extensions: 39015 Number of sequences better than 10.0: 200 Number of HSP's better than 10.0 without gapping: 37350 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 38959 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 52479343733 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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