BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= brS-0065 (722 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;... 322 4e-87 UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 313 3e-84 UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 308 9e-83 UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 304 1e-81 UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 276 4e-73 UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 276 5e-73 UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 270 3e-71 UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 262 8e-69 UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 254 2e-66 UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 254 2e-66 UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 254 2e-66 UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 246 6e-64 UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 244 1e-63 UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 240 3e-62 UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 236 3e-61 UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 234 2e-60 UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 229 4e-59 UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 228 9e-59 UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 227 2e-58 UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 219 4e-56 UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 217 2e-55 UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 217 2e-55 UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 214 2e-54 UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 213 5e-54 UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 212 9e-54 UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 211 1e-53 UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 210 3e-53 UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 210 3e-53 UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 208 8e-53 UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 208 1e-52 UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 207 2e-52 UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 206 3e-52 UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 205 7e-52 UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 205 1e-51 UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 205 1e-51 UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 205 1e-51 UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 204 2e-51 UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 203 4e-51 UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 202 7e-51 UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 202 9e-51 UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 202 9e-51 UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 201 1e-50 UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 201 2e-50 UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 200 3e-50 UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 198 9e-50 UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 198 1e-49 UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 198 1e-49 UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 197 2e-49 UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 197 3e-49 UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 196 5e-49 UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 196 5e-49 UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 196 6e-49 UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 196 6e-49 UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 194 1e-48 UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 194 2e-48 UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 192 6e-48 UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 192 6e-48 UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 192 7e-48 UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 191 1e-47 UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 191 2e-47 UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 191 2e-47 UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 190 2e-47 UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 190 2e-47 UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 190 4e-47 UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 189 5e-47 UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 189 7e-47 UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 188 9e-47 UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 188 2e-46 UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 188 2e-46 UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 186 4e-46 UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 186 5e-46 UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 185 1e-45 UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 184 1e-45 UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 184 2e-45 UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 184 3e-45 UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 183 3e-45 UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 183 5e-45 UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 182 6e-45 UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 181 1e-44 UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 181 2e-44 UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R... 179 7e-44 UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 178 1e-43 UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 177 2e-43 UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 177 3e-43 UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 176 4e-43 UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 176 4e-43 UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 176 5e-43 UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 176 5e-43 UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 175 7e-43 UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 175 7e-43 UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 175 9e-43 UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 175 1e-42 UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 173 3e-42 UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 173 5e-42 UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 171 2e-41 UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 169 6e-41 UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 168 1e-40 UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 168 1e-40 UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 168 1e-40 UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 165 1e-39 UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 164 2e-39 UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 164 2e-39 UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 163 4e-39 UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 161 1e-38 UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 161 1e-38 UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 161 2e-38 UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 159 6e-38 UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 157 3e-37 UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 156 6e-37 UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 154 2e-36 UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 154 2e-36 UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 154 2e-36 UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 153 4e-36 UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 150 3e-35 UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 149 9e-35 UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae... 146 5e-34 UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 144 2e-33 UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 143 3e-33 UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 140 2e-32 UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 137 3e-31 UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 132 6e-30 UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 128 1e-28 UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containi... 126 4e-28 UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 121 2e-26 UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 118 1e-25 UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquil... 118 1e-25 UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 116 8e-25 UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 115 1e-24 UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 115 1e-24 UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1;... 115 1e-24 UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 111 1e-23 UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: ... 109 5e-23 UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 108 1e-22 UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Py... 107 3e-22 UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej... 107 4e-22 UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k... 106 6e-22 UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 104 2e-21 UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 103 3e-21 UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 103 6e-21 UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr... 101 2e-20 UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 99 1e-19 UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetrau... 97 5e-19 UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 95 2e-18 UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp.... 95 2e-18 UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 93 5e-18 UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571... 93 6e-18 UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 92 1e-17 UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 92 1e-17 UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 91 2e-17 UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 91 3e-17 UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 90 6e-17 UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae... 87 4e-16 UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R... 87 5e-16 UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 86 1e-15 UniRef50_Q19Q27 Cluster: Acyl-CoA desaturase-like; n=2; Belgica ... 81 3e-14 UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestina... 81 4e-14 UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 80 6e-14 UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba ... 65 2e-09 UniRef50_A7CFG4 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07 UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06 UniRef50_Q3JI08 Cluster: Putative uncharacterized protein; n=3; ... 45 0.002 UniRef50_Q676G7 Cluster: Pyruvate kinase; n=1; Agrobacterium tum... 45 0.002 UniRef50_A5P062 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002 UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 44 0.004 UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 43 0.007 UniRef50_A5BYI4 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 43 0.009 UniRef50_Q4JN61 Cluster: CG7362-PA; n=1; uncultured bacterium BA... 39 0.11 UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN full... 38 0.33 UniRef50_A0IJJ4 Cluster: HpcH/HpaI aldolase; n=2; Bacteria|Rep: ... 36 0.77 UniRef50_Q54CD8 Cluster: Putative RNA helicase; n=2; Dictyosteli... 36 1.3 UniRef50_A6RIB2 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1 UniRef50_A3LQY4 Cluster: Predicted protein; n=1; Pichia stipitis... 34 3.1 UniRef50_Q0EZ03 Cluster: Putative uncharacterized protein; n=2; ... 34 4.1 UniRef50_A7TH49 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1 UniRef50_Q9LSA0 Cluster: Emb|CAB62463.1; n=3; Arabidopsis thalia... 33 5.4 UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|... 33 5.4 UniRef50_P23522 Cluster: 2-dehydro-3-deoxyglucarate aldolase; n=... 33 5.4 UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1; Ca... 33 7.1 UniRef50_Q893T5 Cluster: Flagellar hook-associated protein 1; n=... 33 7.1 UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1 UniRef50_Q1NHC0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1 UniRef50_Q0YHY4 Cluster: Protein-glutamate O-methyltransferase; ... 33 7.1 UniRef50_Q04GL6 Cluster: RecG-like helicase; n=5; Lactobacillale... 33 7.1 UniRef50_A0Y985 Cluster: Zinc-containing alcohol dehydrogenase s... 33 7.1 UniRef50_Q949D7 Cluster: Putative uncharacterized protein C555ER... 33 7.1 UniRef50_Q8F846 Cluster: Putative uncharacterized protein; n=2; ... 33 9.4 UniRef50_A3XHP8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4 >UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 461 Score = 322 bits (792), Expect = 4e-87 Identities = 155/233 (66%), Positives = 178/233 (76%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N GMLGSRKGVNLP VDLPA+SEKDK DL FG+E GV+M+FASFIR +H++R +L Sbjct: 127 NGGMLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKATDVHQVREVL 186 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 GE+G +IKIISKIEN +G+ DEI+ SDGIMVARGDLGIEIPPEKVFLAQK MI+RCN Sbjct: 187 GEQGAHIKIISKIENQEGVAKFDEILEASDGIMVARGDLGIEIPPEKVFLAQKMMISRCN 246 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 ++GK VICATQMLESMV PRPTRAE SDVANA+LDGADCVMLSGETAKG YPVE V M Sbjct: 247 KIGKSVICATQMLESMVNNPRPTRAETSDVANAVLDGADCVMLSGETAKGKYPVEAVSMM 306 Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 I +EAEA ++HRQ F +L EV P KCLA AI+V+ Sbjct: 307 HRISREAEAAVFHRQQFEELTREVDMPTSAGLTVAIAAVEASYKCLAGAIIVL 359 >UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 744 Score = 313 bits (769), Expect = 3e-84 Identities = 148/208 (71%), Positives = 170/208 (81%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192 Q +N G LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+ AL EIR Sbjct: 129 QVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIR 188 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 +LG G IKIISKIENHQG+VN+D+II ESDGIMVARGD+GIEIP E V LAQK+++A Sbjct: 189 QVLGPAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVA 248 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 +CN+VGKPVICATQM+ESM KPRPTRAE SDVANAI DG D VMLSGETAKG YPVECV Sbjct: 249 KCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECV 308 Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEVK 636 MA IC + EAV+W+ L N L E++ Sbjct: 309 QCMARICAKVEAVLWYESLQNSLKREIR 336 >UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Pyruvate kinase (PK) - Tribolium castaneum Length = 557 Score = 308 bits (756), Expect = 9e-83 Identities = 138/233 (59%), Positives = 174/233 (74%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 +N GMLGS K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN + E+R + Sbjct: 205 ENGGMLGSCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDV 264 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 LG G I IISKIENHQG+ N+DEII SDGIM+ RGDL +EI PEK+FLAQK++IA+C Sbjct: 265 LGRAGNKILIISKIENHQGVHNIDEIIKASDGIMIGRGDLAVEIGPEKLFLAQKSIIAKC 324 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N+ GKPVICA Q+L SM+K+PRPTRAE +DVANA+LDG DCVML+GET G +P+EC+ Sbjct: 325 NKAGKPVICANQLLYSMIKRPRPTRAECTDVANAVLDGVDCVMLTGETFLGQHPIECIRA 384 Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVV 717 + ICKEAE IW++ F +L+ +PP++ +CLA+AI+V Sbjct: 385 ASKICKEAEGAIWYKHHFRELIGHARPPLETSHTICIAAVEAANQCLAAAIIV 437 >UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L - Homo sapiens (Human) Length = 574 Score = 304 bits (747), Expect = 1e-81 Identities = 147/236 (62%), Positives = 174/236 (73%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192 Q +N G+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R Sbjct: 239 QVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVR 298 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 LG +G IKIISKIENH+G+ DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI Sbjct: 299 AALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIG 358 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 RCN GKPV+CATQMLESM+ KPRPTRAE SDVANA+LDGADC+MLSGETAKG++PVE V Sbjct: 359 RCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAV 418 Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 I +EAEA ++HRQLF +L DP KC A+AI+V+ Sbjct: 419 KMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVL 474 >UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep: Pyruvate kinase - Leishmania mexicana Length = 499 Score = 276 bits (677), Expect = 4e-73 Identities = 137/233 (58%), Positives = 166/233 (71%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+ + R+GVNLPG VDLPAVS KD+ DL FGVEQGVDMIFASFIR+ + ++R L Sbjct: 168 NSHTISDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKAL 227 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G KG++I II KIENHQG+ N+D II ESDGIMVARGDLG+EIP EKV +AQK +I++CN Sbjct: 228 GPKGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCN 287 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 GKPVICATQMLESM PRPTRAE+SDVANA+ +GADCVMLSGETAKG YP E V M Sbjct: 288 VAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYM 347 Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 A IC EA++ + FN + P+ ++ A A+VV+ Sbjct: 348 ARICLEAQSALNEYVFFNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVL 400 >UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: Pyruvate kinase - Neurospora crassa Length = 527 Score = 276 bits (676), Expect = 5e-73 Identities = 135/208 (64%), Positives = 158/208 (75%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G + SRKGVNLP VDLPA+SEKDK+DL FGV+ VDM+FASFIR G + +IR +L Sbjct: 182 NNGYISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVL 241 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 GE GK I+II+KIEN QG+ N EI+AE+DG+MVARGDLGIEIP +VF AQK +IA CN Sbjct: 242 GEDGKQIQIIAKIENRQGLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCN 301 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 GKPVICATQMLESM+K PRPTRAEISDV NA+ DGADCVMLSGETAKG YP E V M Sbjct: 302 IAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGAYPTEAVREM 361 Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPI 645 + +AE I + F +L S K P+ Sbjct: 362 SEAVLKAENTIPYVSHFEELCSLAKRPV 389 >UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organisms|Rep: Pyruvate kinase - Eimeria tenella Length = 531 Score = 270 bits (661), Expect = 3e-71 Identities = 126/210 (60%), Positives = 160/210 (76%), Gaps = 1/210 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGI 198 N ++G++K +NLPG+ VDLP + EKDK+D+L FG+ G + I ASF+++ + IR I Sbjct: 203 NPAIIGNKKNMNLPGVKVDLPVIGEKDKNDILNFGIPMGCNFIAASFVQSADDVRYIRSI 262 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 LG KG+NIKII KIEN +G++N DEI+ E+DGIM+ARGDLG+EIPPEKVFLAQK MI++C Sbjct: 263 LGTKGRNIKIIPKIENVEGLLNFDEILQEADGIMIARGDLGMEIPPEKVFLAQKMMISKC 322 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N GKPVI ATQMLESM K PRPTRAE +DVANA+LDG DCVMLSGETA G +PV+ V Sbjct: 323 NVAGKPVITATQMLESMTKNPRPTRAEAADVANAVLDGTDCVMLSGETANGSFPVQAVTV 382 Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPID 648 M+ +C EAE I ++Q+F PID Sbjct: 383 MSRVCFEAEGCIDYQQVFRATCQATMTPID 412 >UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62; Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme - Glycine max (Soybean) Length = 511 Score = 262 bits (641), Expect = 8e-69 Identities = 126/235 (53%), Positives = 163/235 (69%), Gaps = 1/235 (0%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRG 195 +N LG RK VNLPG+ VDLP ++EKDK D+L +GV +DMI SF+R G+ L +R Sbjct: 168 ENTATLGERKNVNLPGVVVDLPTLTEKDKEDILGWGVPNKIDMIALSFVRKGSDLVNVRK 227 Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 +LG KNI+++SK+EN +G++N DEI+ E+D MVARGDLG+EIP EK+FLAQK MI + Sbjct: 228 VLGPHAKNIQLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYK 287 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 CN VGKPV+ ATQMLESM+K PRPTRAE +DVANA+LDG DCVMLSGE+A G YP V Sbjct: 288 CNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVK 347 Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 MA IC EAE+ + + +F +++ P+ P K A IVV+ Sbjct: 348 IMARICIEAESSLDYGAIFKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVL 402 >UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organisms|Rep: Pyruvate kinase - Vibrio cholerae Length = 470 Score = 254 bits (622), Expect = 2e-66 Identities = 125/192 (65%), Positives = 147/192 (76%), Gaps = 1/192 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G LG KGVNLPG+ V+LPA+SEKDK+DL FG EQGVD + ASFIR G+ + EIR +L Sbjct: 148 NNGALGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVL 207 Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 G +NI+IISKIEN +G+ N DEI+ SDGIMVARGDLG+EIP E+V AQK MI +C Sbjct: 208 ASHGGQNIQIISKIENQEGLDNFDEILELSDGIMVARGDLGVEIPAEEVIFAQKMMIEKC 267 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 NR K VI ATQML+SM+K PRPTRAE DVANAI+DG D VMLSGETAKG YPVE V Sbjct: 268 NRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKYPVEAVKI 327 Query: 559 MANICKEAEAVI 594 MA I + + V+ Sbjct: 328 MAQIAERTDPVL 339 >UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's yeast) Length = 506 Score = 254 bits (622), Expect = 2e-66 Identities = 124/210 (59%), Positives = 149/210 (70%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192 Q N+G + S KGVNLP VDLP +S KD DL FGV G+ ++FASFIR + IR Sbjct: 168 QAVNSGYIASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIR 227 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 LG +G++IKIISKIEN QG+ N DEI+ +DG+M+ARGDLGIEI +V QK +IA Sbjct: 228 KALGSEGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIA 287 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 +CN GKPVICATQML+SM PRPTRAE+SDV NA+LDGADCVMLSGETAKGDYPV V Sbjct: 288 KCNLAGKPVICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAV 347 Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEVKPP 642 + MA AE+ I H L++DL P Sbjct: 348 NIMAATALIAESTIAHLALYDDLRDATPKP 377 >UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 510 Score = 254 bits (621), Expect = 2e-66 Identities = 127/235 (54%), Positives = 162/235 (68%), Gaps = 1/235 (0%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRG 195 +N+ +LG RK VNLPGI VDLP ++EKDK D++ +GV +D+I SF+R G+ L E+R Sbjct: 163 ENSAILGERKNVNLPGIVVDLPTLTEKDKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRR 222 Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 +LGE KNI ++SK+EN +G++N ++I+ SD MVARGDLG+EIP EK+FLAQKTMI Sbjct: 223 LLGEHSKNIMLMSKVENQEGVMNCEKILENSDAFMVARGDLGMEIPIEKMFLAQKTMIKM 282 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 N +GKPV+ ATQMLESM PRPTRAE +DVANA+LDG DCVMLSGETA G +P V Sbjct: 283 ANALGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPEAAVL 342 Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 TM+ ICKEAE I + L + V P+ P ASAIVV+ Sbjct: 343 TMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASVVSTAQSVFASAIVVL 397 >UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 1010 Score = 246 bits (601), Expect = 6e-64 Identities = 120/197 (60%), Positives = 151/197 (76%), Gaps = 2/197 (1%) Frame = +1 Query: 52 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE--KGKNIK 225 +N G+ DL A++E+DK DL FG +Q VDMIFASFIR+ AL EIR LG ++IK Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIK 318 Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405 IISKIE+ Q + N+DEII ESDGIMVA G++G EI E V LAQK+++A+CN+VGKPVIC Sbjct: 319 IISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVIC 378 Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585 A QM+ SM+ KPRPTRAE SDVANAILDG D ++LS ETAKG YPV+CV MA IC + E Sbjct: 379 ANQMMNSMITKPRPTRAESSDVANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVE 438 Query: 586 AVIWHRQLFNDLVSEVK 636 +V+W+ + N+L SEV+ Sbjct: 439 SVLWYESIQNNLKSEVR 455 >UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: Pyruvate kinase I - Salmonella typhimurium Length = 470 Score = 244 bits (598), Expect = 1e-63 Identities = 123/200 (61%), Positives = 148/200 (74%), Gaps = 1/200 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G LG KGVNLPG+ + LPA++EKDK DL+FG EQGVD + ASFIR + + EIR L Sbjct: 148 NNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHL 207 Query: 202 -GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 G+NI+IISKIEN +G+ N DEI+ SDGIMVARGDLG+EIP E+V AQK MI +C Sbjct: 208 KAHGGENIQIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKC 267 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 R K VI ATQML+SM+K PRPTRAE DVANAILDG D VMLSGE+AKG YP+E V Sbjct: 268 IRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSI 327 Query: 559 MANICKEAEAVIWHRQLFND 618 MA IC+ + V+ R +N+ Sbjct: 328 MATICERTDRVMNSRLDYNN 347 >UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Oligohymenophorea|Rep: Pyruvate kinase family protein - Tetrahymena thermophila SB210 Length = 505 Score = 240 bits (587), Expect = 3e-62 Identities = 114/198 (57%), Positives = 148/198 (74%), Gaps = 1/198 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGI 198 N +G +K +NLPG VDLP V+EKD+ D++ FG++ G+D I SF R + +R I Sbjct: 171 NTCSIGEKKNMNLPGAIVDLPTVTEKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDI 230 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 LG +G++IKII+KIEN +G+ N ++I+ +DGIMVARGDLG+EIPP+KVF+AQK MI + Sbjct: 231 LGPQGEHIKIIAKIENQEGLHNYEQILDAADGIMVARGDLGMEIPPQKVFVAQKWMIRKA 290 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 GKP+I ATQM+ESM+K PRPTRAE SDVANA+LDG D VMLSGETA G +P++ V T Sbjct: 291 LEKGKPIITATQMMESMIKNPRPTRAEASDVANAVLDGTDAVMLSGETANGSFPIQAVQT 350 Query: 559 MANICKEAEAVIWHRQLF 612 MA IC EAE +RQ F Sbjct: 351 MAYICSEAELCYDNRQTF 368 >UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: Pyruvate kinase - Bacillus subtilis Length = 585 Score = 236 bits (578), Expect = 3e-61 Identities = 113/199 (56%), Positives = 148/199 (74%), Gaps = 1/199 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G L ++KGVN+PG+ V+LP ++EKD D++FG+EQGVD I SFIR + EIR +L Sbjct: 148 NNGTLKNKKGVNVPGVSVNLPGITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELL 207 Query: 202 GE-KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E ++I+II KIEN +G+ N+D I+ SDG+MVARGDLG+EIP E+V L QK +I +C Sbjct: 208 EEHNAQDIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKC 267 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N +GKPVI ATQML+SM + PRPTRAE SDVANAI DG D +MLSGETA G YPVE V T Sbjct: 268 NALGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEAVQT 327 Query: 559 MANICKEAEAVIWHRQLFN 615 M NI +E + ++++ + Sbjct: 328 MHNIASRSEEALNYKEILS 346 >UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piroplasmida|Rep: Pyruvate kinase, putative - Theileria annulata Length = 513 Score = 234 bits (572), Expect = 2e-60 Identities = 116/197 (58%), Positives = 142/197 (72%), Gaps = 1/197 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGI 198 N +G K +NLPG+ V+LP ++E DK +L FG+ +D I SF + + +R + Sbjct: 185 NNAKIGEYKNMNLPGVKVELPVLTESDKDYILNFGIPNQMDFIALSFTQTAEEVKYVREL 244 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 LGEKGK+IKII KIEN +G+ N DEI+ SDGIMVARGDLG+E+P EKV LAQK MI R Sbjct: 245 LGEKGKHIKIIPKIENIEGLANYDEILEASDGIMVARGDLGMEMPIEKVCLAQKMMIKRA 304 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N GKP+I ATQMLESMV PRPTRAE +DV NA+LDG+DCVMLSGETA G +PVECV Sbjct: 305 NMCGKPIITATQMLESMVNNPRPTRAESADVINAVLDGSDCVMLSGETAGGRFPVECVKI 364 Query: 559 MANICKEAEAVIWHRQL 609 MA +C EAE + R L Sbjct: 365 MAKLCFEAENCLSTRDL 381 >UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 554 Score = 229 bits (561), Expect = 4e-59 Identities = 109/233 (46%), Positives = 157/233 (67%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G L + V LP I +DLPAVSEKD D+ F ++ VD +FAS +R+ + E+R +L Sbjct: 184 HGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVL 243 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 GEKGK+IKII+K+++ + EI+ +DG++++R DLG +IP EK+F+ QK+++ +CN Sbjct: 244 GEKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCN 303 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 +VGKPVI A+ +LESM P PTRAE D+ANAI+DGADC+MLS E A G +P E V T Sbjct: 304 KVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATC 363 Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 +C+EAE V+W R LF+DLVSEV+ +D + A+ I+V+ Sbjct: 364 DTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVL 416 >UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep: Pyruvate kinase - Phaeodactylum tricornutum Length = 543 Score = 228 bits (558), Expect = 9e-59 Identities = 117/207 (56%), Positives = 142/207 (68%), Gaps = 2/207 (0%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRG 195 DN +G RK +NLPG+ VDLP +EKD D++ FG++ VD I ASF+R + + +R Sbjct: 179 DNNASMGERKNMNLPGVKVDLPTFTEKDVDDIVNFGIKHKVDFIAASFVRKQSDVANLRQ 238 Query: 196 ILGEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 +L E G + IKI KIEN +G+ N D I+ +D IMVARGDLG+EIPP KVFLAQK MI Sbjct: 239 LLAENGGQQIKICCKIENQEGLENYDAILQATDSIMVARGDLGMEIPPAKVFLAQKMMIR 298 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 N GKPVI ATQMLESM+ PRPTRAE SDVANA+LDG DCVMLSGETA G Y E V Sbjct: 299 EANIAGKPVITATQMLESMINNPRPTRAECSDVANAVLDGTDCVMLSGETANGPYFEEAV 358 Query: 553 HTMANICKEAEAVIWHRQLFNDLVSEV 633 MA C EAE + L++ + S V Sbjct: 359 KVMARTCCEAENSRNYNSLYSAVRSSV 385 >UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis|Rep: Pyruvate kinase - Achlya bisexualis (Water mold) Length = 517 Score = 227 bits (555), Expect = 2e-58 Identities = 112/212 (52%), Positives = 149/212 (70%), Gaps = 8/212 (3%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 +N+ +LGSRKGVNLPG+ VDLPA++ KDK D+ FGVE +D I SF+R +++++ Sbjct: 184 ENSEVLGSRKGVNLPGLVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVRKPEDVNDVKDF 243 Query: 199 LGEKGKNI--------KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLA 354 + IISKIEN++G+ N D I+ SDGIMVARGDLG+EIP ++V Sbjct: 244 VNSVMPKYWPAGHPAPLIISKIENYEGVSNFDRILEVSDGIMVARGDLGVEIPMQEVLTC 303 Query: 355 QKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGD 534 QK M+++CN GKPVI ATQMLESM++ PRPTRAEI DV NA+LDGAD VMLSGE A+G Sbjct: 304 QKDMVSKCNAAGKPVIVATQMLESMIRNPRPTRAEILDVGNAVLDGADAVMLSGEVAQGK 363 Query: 535 YPVECVHTMANICKEAEAVIWHRQLFNDLVSE 630 +PVE V TM ++ KEA+A + Q + +S+ Sbjct: 364 WPVESVKTMMSVIKEADAYVKREQYKKEALSQ 395 >UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803) Length = 591 Score = 219 bits (536), Expect = 4e-56 Identities = 101/186 (54%), Positives = 137/186 (73%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S KGVN PG+ + + A+++KDK DL+FG++QGVD + SF+RN + EI+G++ Sbjct: 158 GTLSSNKGVNFPGVCLSVKAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAA 217 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 GK++ +I+KIE H+ + ++ ++ + DG+MVARGDLG+E+P E V + QK +IA NR+ Sbjct: 218 AGKSVPVIAKIEKHEAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRL 277 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G PVI ATQML+SMV PRPTRAE+SDVANAILDG D VMLS ETA G +PVE V MA Sbjct: 278 GIPVITATQMLDSMVNSPRPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAK 337 Query: 568 ICKEAE 585 I + E Sbjct: 338 IAERIE 343 >UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase family protein - Tetrahymena thermophila SB210 Length = 495 Score = 217 bits (531), Expect = 2e-55 Identities = 114/210 (54%), Positives = 144/210 (68%), Gaps = 19/210 (9%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKD------KSDLLF-------------GVEQG 135 Q +N G+L K V LPG+ +DLP +SE+ K+D F G+E+G Sbjct: 147 QFENEGILNEVKNVRLPGVKIDLPTISEEGIFIIQFKNDQQFQLILIDEDFIISQGLEKG 206 Query: 136 VDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGD 315 VD I SF+R+G + +R +L +G++IKII+KIEN +GM N ++I+ SDGIMVARGD Sbjct: 207 VDFIAVSFVRSGEDIEYVRDLLSPRGEHIKIIAKIENIEGMENFEDILKSSDGIMVARGD 266 Query: 316 LGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGA 495 LG+ IP +KVF+AQK MI RC VGKPVI ATQM+ESMVK PRPTRAE SDVANA+LDG Sbjct: 267 LGMVIPAQKVFVAQKWMIDRCLEVGKPVITATQMMESMVKNPRPTRAEASDVANAVLDGT 326 Query: 496 DCVMLSGETAKGDYPVECVHTMANICKEAE 585 D VMLS ET+ G YP ECV + I +EAE Sbjct: 327 DAVMLSTETSVGQYPCECVEITSQIAREAE 356 >UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerofaciens ATCC 25986|Rep: Pyruvate kinase - Collinsella aerofaciens ATCC 25986 Length = 486 Score = 217 bits (531), Expect = 2e-55 Identities = 107/189 (56%), Positives = 137/189 (72%), Gaps = 1/189 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G++G RKGVN+P + + LPA++E+D+ D+LFG+ + +D I ASFIR+G ++ IR + Sbjct: 152 NDGLIGERKGVNMPNVNISLPAITERDRQDILFGLTENIDYIAASFIRDGESVRGIRELC 211 Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E G +++ I KIE G+ N DEI+ SDGIMVARGDLGIEI PE V QK +IA+C Sbjct: 212 RENGGEHVTIFPKIECALGVENFDEILEASDGIMVARGDLGIEIKPELVPHIQKEIIAKC 271 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N KPVI ATQML+SM + PRPTRAE++DVANAI DG D VMLSGE+A G YPVE V Sbjct: 272 NAAYKPVITATQMLDSMQQNPRPTRAEVADVANAIYDGTDAVMLSGESAAGKYPVEAVKM 331 Query: 559 MANICKEAE 585 A+I E E Sbjct: 332 QASIALETE 340 >UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep: Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803) Length = 483 Score = 214 bits (523), Expect = 2e-54 Identities = 105/187 (56%), Positives = 137/187 (73%), Gaps = 1/187 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L SRKGVNLPG+ + LP+++ KDK DL FG+ QG+D + SF+R G +H ++ L E Sbjct: 163 GILKSRKGVNLPGLVLTLPSMTTKDKQDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAE 222 Query: 208 KGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 +G ++ +I+KIE Q + NL+EI+A S+GIMVARGDLG+E+ PEKV QK +I RCN Sbjct: 223 RGHPDLPVIAKIEKPQAIDNLEEIVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNV 282 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 PVI ATQML+SM++ RPTRAE SDVANAILDG D VMLSGE+A G YPV+ V + Sbjct: 283 RAIPVITATQMLDSMIQNSRPTRAEASDVANAILDGTDAVMLSGESAVGQYPVKSVQMLR 342 Query: 565 NICKEAE 585 I +E E Sbjct: 343 KIAEETE 349 >UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psychrophila|Rep: Pyruvate kinase - Desulfotalea psychrophila Length = 581 Score = 213 bits (519), Expect = 5e-54 Identities = 108/206 (52%), Positives = 142/206 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L SRK V LP V+LP++SEKDK D+ FGVEQ VD I ASF+R + +R I+ + Sbjct: 147 GILSSRKRVALPDNEVNLPSLSEKDKEDIAFGVEQDVDFIAASFVRQAGDVWAVRKIIED 206 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G + +II+KIEN QG+ NLDEI+ ++GIMVARGDLG+E+P E+V + QK++I NR+ Sbjct: 207 NGGDQEIIAKIENRQGVNNLDEILQAANGIMVARGDLGVEVPAEEVPIIQKSIIKAANRL 266 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM+ P PTRAE +DV NAI DG D VMLSGETA G YPV+ V + Sbjct: 267 GKPVITATQMLESMITCPTPTRAEANDVTNAIFDGTDAVMLSGETAIGKYPVQAVAFLVR 326 Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPI 645 AE + + + + + +P I Sbjct: 327 CATIAENALDYDHILANGLQNRRPTI 352 >UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: Pyruvate kinase - Bacteroides fragilis Length = 485 Score = 212 bits (517), Expect = 9e-54 Identities = 98/188 (52%), Positives = 138/188 (73%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N LGSRK VN+PG+ ++LP+++EKD++++L+ +E+ +D I SF+RN + +IRGIL Sbjct: 144 NEATLGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRGIL 203 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 +I+II+KIEN +G+ N+DEI+ +DG+MVARGDLGIE+P E++ Q+ +I +C Sbjct: 204 DAHNSDIRIIAKIENQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRMLIRKCI 263 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 KPVI ATQML +M+ PRPTRAE++D+ANAI D +MLSGETA G YPVE V TM Sbjct: 264 LAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTM 323 Query: 562 ANICKEAE 585 I +AE Sbjct: 324 TKIAAQAE 331 >UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep: Pyruvate kinase - Clostridium phytofermentans ISDg Length = 580 Score = 211 bits (516), Expect = 1e-53 Identities = 109/209 (52%), Positives = 140/209 (66%), Gaps = 1/209 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N GM+ + KGVN+PG+ + +P +S++D D++FG+ QG D I ASF R + +IR IL Sbjct: 146 NGGMISNHKGVNVPGVELSMPFISKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKIL 205 Query: 202 GEKGKN-IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E N + II+KIEN QG+ N+DEII SDGIMVARGD+G+EIP E+V + QK +I + Sbjct: 206 NEYNCNTVNIIAKIENLQGVNNIDEIIRVSDGIMVARGDMGVEIPLEEVPVIQKMIIKKV 265 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 K VI ATQML+SM+K PRPTRAE +DVANAI DG +MLSGETA G YPVE + T Sbjct: 266 YNAEKQVITATQMLDSMMKNPRPTRAEATDVANAIYDGTSAIMLSGETAAGLYPVEALRT 325 Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPI 645 M I K EA I + F S P + Sbjct: 326 MVKIAKRTEADIDYTSRFRKRDSLTNPDV 354 >UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera araneosa HTCC2155 Length = 485 Score = 210 bits (513), Expect = 3e-53 Identities = 105/188 (55%), Positives = 130/188 (69%), Gaps = 1/188 (0%) Frame = +1 Query: 25 AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGIL 201 AG L S KG+NLP + PA++EKD+ DL F +E +D + SF+R G L I + Sbjct: 148 AGKLTSNKGINLPETDIQSPALTEKDERDLKFIIENDAIDFVALSFVRKGEDLDIIHAAM 207 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 + GK +ISKIE +V++D II +SD +MVARGDLG+EIP EKV +AQKTMI +C Sbjct: 208 DKIGKRKPVISKIEKPSALVDIDAIIEKSDALMVARGDLGVEIPSEKVPVAQKTMIRKCI 267 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 GKP I ATQML+SM++ PRPTRAE SDVANA+LDGA VMLSGETA G YPVE V M Sbjct: 268 EQGKPCIVATQMLDSMIRNPRPTRAEASDVANAVLDGASAVMLSGETASGSYPVEAVQMM 327 Query: 562 ANICKEAE 585 I +E E Sbjct: 328 TKIIRETE 335 >UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase - Protochlamydia amoebophila (strain UWE25) Length = 598 Score = 210 bits (512), Expect = 3e-53 Identities = 104/191 (54%), Positives = 136/191 (71%), Gaps = 1/191 (0%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 +N+GM+ S KGVN+P ++LPAV+EKD D+ FG Q +D+I ASF+R+ + EI+ + Sbjct: 147 NNSGMIRSSKGVNIPNTSLNLPAVTEKDIDDIRFGCSQDIDLIAASFVRSAEHVLEIKRL 206 Query: 199 LG-EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 L EK +I +I+KIEN +G+ N D I+ +DGIM+ARGDLG+E+P V QK MI + Sbjct: 207 LADEKKTDILVIAKIENSEGVQNFDSIVQAADGIMIARGDLGVEVPLSHVPRLQKMMIRK 266 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 GKPV+ ATQMLESM+ PRPTRAE SDVANAI D +MLSGETA G YPVE V+ Sbjct: 267 SYLAGKPVVTATQMLESMINNPRPTRAETSDVANAIYDSTSAIMLSGETAIGRYPVETVN 326 Query: 556 TMANICKEAEA 588 M +I +EAEA Sbjct: 327 VMRSIVEEAEA 337 >UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadales|Rep: Pyruvate kinase - Geobacter sulfurreducens Length = 480 Score = 208 bits (509), Expect = 8e-53 Identities = 102/186 (54%), Positives = 128/186 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 GML KG+NLPG+ V P++SEKD DL F +E GVD I SF+R A + ++ IL E Sbjct: 152 GMLKDLKGINLPGVKVSAPSLSEKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFE 211 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + + +++KIE + + N I+ +D +MVARGDLG+EI PEKV L QK +I CN Sbjct: 212 RDVQVPVVAKIEKPEALRNFKSILKVADAVMVARGDLGVEISPEKVPLFQKKIIRACNEA 271 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM+ PRPTRAE SDVANAILDG D VMLSGETA G +P+E V TM Sbjct: 272 GKPVITATQMLESMISHPRPTRAETSDVANAILDGTDAVMLSGETASGQFPLEAVRTMDK 331 Query: 568 ICKEAE 585 + + E Sbjct: 332 VALDVE 337 >UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep: Pyruvate kinase - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 485 Score = 208 bits (508), Expect = 1e-52 Identities = 96/188 (51%), Positives = 138/188 (73%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N LGSRK VN+PG+ ++LP+++EKD++++L+ ++ +D I SF+RN + +I+ IL Sbjct: 145 NDATLGSRKSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRIL 204 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E+ IKII+KIEN +G+ N++EI+ + G+M+ARGDLGIE+P EK+ Q+ +I +C Sbjct: 205 DERNSPIKIIAKIENQEGVDNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCV 264 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 V KPVI ATQML SM+ PRPTRAE++D+ANAI D +MLSGETA G YP+E V TM Sbjct: 265 EVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPIEAVQTM 324 Query: 562 ANICKEAE 585 + +EAE Sbjct: 325 TKVAREAE 332 >UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: Pyruvate kinase - Leptospira interrogans Length = 478 Score = 207 bits (506), Expect = 2e-52 Identities = 103/188 (54%), Positives = 131/188 (69%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L S KG+NLPG P+ PA+SEKD DL F + GVD SF+R GA L R L Sbjct: 157 GILWSNKGINLPGTPISAPALSEKDIEDLKFALSLGVDYAALSFVRTGADLELARSYL-- 214 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +G +I+KIE + + N++EII +DGIM+ARGDLG+EI EKV + QK +I + N+ Sbjct: 215 EGTYTGLIAKIERPEAIGNIEEIIERADGIMIARGDLGVEIDTEKVPILQKELIYKLNQA 274 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM++ PRPTRAE SDVANA++DG D VMLS E+A G YPVE V M+ Sbjct: 275 GKPVITATQMLESMIENPRPTRAEASDVANAVMDGTDAVMLSAESANGHYPVESVEIMSK 334 Query: 568 ICKEAEAV 591 I +E E + Sbjct: 335 IIQETETI 342 >UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula marismortui (Halobacterium marismortui) Length = 610 Score = 206 bits (504), Expect = 3e-52 Identities = 102/193 (52%), Positives = 133/193 (68%) Frame = +1 Query: 7 FEQQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHE 186 F +N G L +RKGVN+PG+ +DLP ++E D+ +L E+ D + ASF+R+G ++E Sbjct: 151 FATVENGGELAARKGVNVPGVELDLPTITENDEQELDVAAEKEPDFVAASFVRDGEDIYE 210 Query: 187 IRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTM 366 I L E+G +I II+KIE + NLD II E+ G+MVARGDLG+E P E V + QK + Sbjct: 211 ISQALEERGVDIPIIAKIERAGAVENLDSIIDEAYGVMVARGDLGVECPLEDVPIIQKRI 270 Query: 367 IARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVE 546 I RC+ G PVI AT+ML+SMV RPTRAE SDVANA+LDG D VMLSGETA GD+P Sbjct: 271 IRRCHEAGVPVITATEMLDSMVHSRRPTRAEASDVANAVLDGTDAVMLSGETAIGDHPAR 330 Query: 547 CVHTMANICKEAE 585 V TM I ++ E Sbjct: 331 VVETMDRIIRDVE 343 >UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep: Pyruvate kinase - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 619 Score = 205 bits (501), Expect = 7e-52 Identities = 106/194 (54%), Positives = 133/194 (68%), Gaps = 8/194 (4%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-- 201 G L + KGVN PG+ + + AV+ KDK DL FG+ QGVD + SF+R+ + + E+R ++ Sbjct: 156 GTLSNNKGVNFPGVRLSIRAVTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELIAS 215 Query: 202 ------GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKT 363 G K + II KIE H+ + L +I+A SDG+MVARGDLG+E+P E+V + QK Sbjct: 216 AKRPSSGSADKRVPIIVKIEKHEAIEQLPQILALSDGVMVARGDLGVELPAEEVPILQKR 275 Query: 364 MIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPV 543 +IA N +G PVI ATQML+SMV PRPTRAEISDVANAILDG D VMLS ETA G YPV Sbjct: 276 VIALANSLGIPVITATQMLDSMVHSPRPTRAEISDVANAILDGTDAVMLSNETAVGKYPV 335 Query: 544 ECVHTMANICKEAE 585 E V TMA I E Sbjct: 336 EAVATMARIAVRTE 349 >UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep: Pyruvate kinase - Anaeromyxobacter dehalogenans (strain 2CP-C) Length = 489 Score = 205 bits (500), Expect = 1e-51 Identities = 101/187 (54%), Positives = 130/187 (69%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G LG KG+NLPG+ + A+SEKD++D+ FG+ GVD + SF+R + R + Sbjct: 151 GWLGEHKGINLPGVALRAEALSEKDRADVAFGISHGVDYVALSFVRTPEDIALCRDEMER 210 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G+ + II+KIE + + NLD IIA +DG+MVARGDLG+EI PE+V L QK + ++ N Sbjct: 211 AGRVVPIIAKIEKPEAIDNLDAIIAAADGVMVARGDLGVEILPERVPLLQKEICSKANAS 270 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQML SM++ PRPTRAE SDVAN I DGAD VMLSGETA G +P+ V M Sbjct: 271 GKPVIIATQMLNSMIEHPRPTRAEASDVANGIWDGADAVMLSGETASGRFPLAAVQMMDR 330 Query: 568 ICKEAEA 588 I +EAEA Sbjct: 331 IVREAEA 337 >UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to pyruvate kinase - Candidatus Kuenenia stuttgartiensis Length = 472 Score = 205 bits (500), Expect = 1e-51 Identities = 99/186 (53%), Positives = 134/186 (72%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L SRKG+N+P + + +++EKDK DL FG+EQGVD + SF++ + E+R ++ + Sbjct: 151 GVLTSRKGINIPARSLPVSSLTEKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQK 210 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 KGK I II+KIE H+ + N+++I+ +D IMVARGDLG+EIP E+V QK +I NR Sbjct: 211 KGKTIPIIAKIEKHEAVDNIEKIVNTADAIMVARGDLGVEIPLERVPSVQKMIIRLANRY 270 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQML SMV RPTRAE++DVANAILDG+D VMLS E+A G YP + V + Sbjct: 271 GKPVITATQMLASMVNNYRPTRAEVTDVANAILDGSDAVMLSEESAIGRYPADAVLMLTK 330 Query: 568 ICKEAE 585 I K+ E Sbjct: 331 IAKQIE 336 >UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyruvate kinase - Acidobacteria bacterium (strain Ellin345) Length = 509 Score = 205 bits (500), Expect = 1e-51 Identities = 100/189 (52%), Positives = 129/189 (68%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G L +G+N+PG + +PA++ KD DL FG++ GVD + SF+R L ++R + Sbjct: 165 NGGELKEHQGINIPGAILSIPALTNKDLEDLAFGLKNGVDAVAISFVRTANDLKQVRNAI 224 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E N+ +I+K+E Q + +L+EI E+DG+MVARGDLG+E+PPEKV + QK +I R Sbjct: 225 SEHQGNVFVIAKLEKPQAIEHLEEIFNETDGVMVARGDLGVEVPPEKVPVLQKHIIKRSQ 284 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 PVI ATQMLESM+ PRPTRAE SDVANAI DG D VMLSGETA G YP E V M Sbjct: 285 SRRIPVITATQMLESMIDNPRPTRAEASDVANAIFDGTDAVMLSGETASGKYPREAVAMM 344 Query: 562 ANICKEAEA 588 A I EAE+ Sbjct: 345 ARIITEAES 353 >UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp. PR1 Length = 476 Score = 204 bits (498), Expect = 2e-51 Identities = 102/195 (52%), Positives = 135/195 (69%), Gaps = 2/195 (1%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G+L SRKG+NLP V P+++EKD DL FG+ + VD I SF+R+ + ++R + Sbjct: 151 HGGILKSRKGINLPNTKVSAPSLTEKDIEDLAFGLSKEVDWIALSFVRSAEDIEDLRERI 210 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 KGK+ KI++KIE + + N+D II +D IMVARGDLG+E+P E V L QK ++ +C Sbjct: 211 EAKGKHCKIVAKIEKPEALENIDGIIEATDAIMVARGDLGVEVPMEIVPLWQKRIVEKCK 270 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 KPVI ATQM+ESM+ PRPTRAE +DVANA+LDGAD VMLS ETA G YPV V M Sbjct: 271 LACKPVIIATQMMESMIVNPRPTRAETNDVANAVLDGADAVMLSAETASGKYPVNAVKAM 330 Query: 562 ANIC--KEAEAVIWH 600 ++I EA A I+H Sbjct: 331 SSIIGYLEANAEIYH 345 >UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi Length = 519 Score = 203 bits (495), Expect = 4e-51 Identities = 99/188 (52%), Positives = 133/188 (70%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+GM+ S K +N PG + A+ ++DK+D+ FG+E G+DM+FASF+ A + EIR ++ Sbjct: 235 NSGMIKSNKSMNFPGTDIGDRALGDEDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLV 294 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G K + ++SKIE+ GM NL EI SDG+M+ARGDLG+EI E +F AQK ++ Sbjct: 295 GSK---VPVVSKIESCLGMRNLKEIALCSDGVMIARGDLGVEIGLENMFSAQKRILYEVK 351 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 R G+PVICATQM+ESM K P R+EISDV NA+LDG DCVMLS E+A G +PVE V M Sbjct: 352 REGRPVICATQMMESMTLKNAPNRSEISDVGNAVLDGCDCVMLSAESAVGMFPVETVKFM 411 Query: 562 ANICKEAE 585 +IC +AE Sbjct: 412 RSICADAE 419 >UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep: Pyruvate kinase - Propionibacterium acnes Length = 477 Score = 202 bits (493), Expect = 7e-51 Identities = 95/188 (50%), Positives = 134/188 (71%) Frame = +1 Query: 25 AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 204 AG +G KG+NLPG+ V +PA+++KD+ +L + ++ G+D++ SF+R+G+ + + I+ Sbjct: 153 AGPVGDHKGINLPGVAVSIPALTKKDEENLRWALKAGIDLVALSFVRHGSDIDRVHEIMD 212 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 E+G+ + +I+K+E Q + NLDEII D +MVARGD+ +E P E+V L QK +I + Sbjct: 213 EEGRTVPVIAKLEKPQAIENLDEIIDVFDAVMVARGDMAVECPLEEVPLIQKQIIEKARL 272 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 KPVI ATQMLESM+ PRPTRAE +DVANAILDGAD VM S ET+ GD+P E V TMA Sbjct: 273 QAKPVIVATQMLESMIHAPRPTRAEAADVANAILDGADGVMTSAETSVGDFPGETVRTMA 332 Query: 565 NICKEAEA 588 I + EA Sbjct: 333 KIVESTEA 340 >UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigroviridis|Rep: Pyruvate kinase - Tetraodon nigroviridis (Green puffer) Length = 569 Score = 202 bits (492), Expect = 9e-51 Identities = 101/171 (59%), Positives = 119/171 (69%), Gaps = 1/171 (0%) Frame = +1 Query: 211 GKNIKIISKIENHQGM-VNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G+ ++ + G + L + + SDGIMVARGDLGIEIP EKVFLAQK MI RCNR Sbjct: 300 GRLSNLVCNCRRYSGFFLGLMKSMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRA 359 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKP+ CATQMLESM+KKPRPTRAE SDVANA+LDGADC+MLSGETAKGDYP+E V T Sbjct: 360 GKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHM 419 Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 I +EAEA +HRQLF +L + DP KC ASA+VV+ Sbjct: 420 IAREAEAATFHRQLFEELRRHSQLTRDPSEAVAVGAVEASFKCCASALVVL 470 Score = 126 bits (305), Expect = 4e-28 Identities = 57/80 (71%), Positives = 68/80 (85%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 +N G LGS+KGVNLPG VDLPAVS+KD DL FGVEQGVDM+FASFIR A +H +R + Sbjct: 203 ENGGTLGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVHAVRAV 262 Query: 199 LGEKGKNIKIISKIENHQGM 258 LGEKGK+IKIISK+ENH+G+ Sbjct: 263 LGEKGKDIKIISKLENHEGV 282 >UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytoplasma|Rep: Pyruvate kinase - Onion yellows phytoplasma Length = 446 Score = 202 bits (492), Expect = 9e-51 Identities = 104/197 (52%), Positives = 136/197 (69%), Gaps = 1/197 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N + SR+GVN+P + +++ +S KD D++F +Q D I ASF+R + +IR IL Sbjct: 147 NTHSIKSRRGVNVPKVNLEMDFISPKDYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKIL 206 Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E+G NI+IISKIEN +G+ NL+EII ESDGIMVARGDLGIE+ E V L Q MI +C Sbjct: 207 QEQGNSNIQIISKIENQEGVDNLEEIIQESDGIMVARGDLGIEVDGELVPLYQTRMITKC 266 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 GKPV+ ATQMLESM + PRPT+AE SDV NA+ +G MLSGE+A G+YPVE V Sbjct: 267 LEYGKPVVVATQMLESMQRNPRPTKAETSDVFNAVREGTTFTMLSGESASGEYPVEAVTY 326 Query: 559 MANICKEAEAVIWHRQL 609 M I +AE V+ ++ L Sbjct: 327 MKKINYQAEKVVNYQAL 343 >UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organisms|Rep: Pyruvate kinase - Uncultured methanogenic archaeon RC-I Length = 583 Score = 201 bits (491), Expect = 1e-50 Identities = 99/192 (51%), Positives = 134/192 (69%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S+KG+NLP + +P+++EKD DL FG+E VDMI SF+R + ++R + + Sbjct: 147 GELKSKKGINLPQSTIRIPSITEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIED 206 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +I IISKIE H+ + N+D II DG+MVARGDLGIEIP +V + QK +I++C Sbjct: 207 NDSDIPIISKIEKHEAVKNIDGIIDVVDGVMVARGDLGIEIPMAEVPIVQKMIISKCIAR 266 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G PVI ATQML+SM++ P PTRAE +DVANA+ DG D +MLSGETA G+YPV+ V TMA Sbjct: 267 GIPVITATQMLDSMIRNPIPTRAEATDVANAVFDGTDALMLSGETAFGEYPVKAVETMAR 326 Query: 568 ICKEAEAVIWHR 603 I K E +++ Sbjct: 327 IAKYTEESTYYK 338 >UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis pacifica SIR-1 Length = 485 Score = 201 bits (490), Expect = 2e-50 Identities = 100/190 (52%), Positives = 133/190 (70%), Gaps = 2/190 (1%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G+L +RKGVNLP + LP++++KD DL F +E GVD + SF+R L E R I+ Sbjct: 152 NGGVLKARKGVNLPDSDLLLPSLTDKDAKDLRFALELGVDFVALSFVRRVEDLEECRKIM 211 Query: 202 GEKGKNIKIISKIENHQGMV--NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 E G+ + +++KIE + + NL +I+ ++GIM+ARGDLG+E+ PE+V L QK +I Sbjct: 212 NEVGRTVPLVAKIEKPEALEPENLPKILDAANGIMIARGDLGVEMGPEEVPLIQKELIKL 271 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 N GK VI ATQML+SM++ PRPTRAE SDVANAILDG+DCVMLSGETA G YP+ V Sbjct: 272 SNERGKLVITATQMLDSMIRNPRPTRAEASDVANAILDGSDCVMLSGETAAGKYPIRAVE 331 Query: 556 TMANICKEAE 585 TM I + E Sbjct: 332 TMDRIIRRIE 341 >UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae|Rep: Pyruvate kinase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 502 Score = 200 bits (488), Expect = 3e-50 Identities = 96/197 (48%), Positives = 138/197 (70%), Gaps = 3/197 (1%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ--GVDMIFASFIRNGAALHE 186 + N G++G +KGVN+P + PA++E+D +D+ FG+ Q G++ I SF+R + E Sbjct: 173 EAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKE 232 Query: 187 IRGILGEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKT 363 +R I E G ++++++KIEN QG+ NLDEII +DGIM+ARGD+GIE+P E V + QK Sbjct: 233 VRRICEETGNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKL 292 Query: 364 MIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPV 543 +I++ N+ GK V+ AT MLESM PR TR+EISDV NA++DG D MLSGE+A G YP Sbjct: 293 IISKVNKAGKIVVTATNMLESMTYNPRATRSEISDVFNAVIDGTDATMLSGESANGKYPR 352 Query: 544 ECVHTMANICKEAEAVI 594 E V TMA + K A+ ++ Sbjct: 353 ESVRTMATVNKNAQTML 369 >UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobacteria|Rep: Pyruvate kinase - Nitratiruptor sp. (strain SB155-2) Length = 458 Score = 198 bits (484), Expect = 9e-50 Identities = 97/190 (51%), Positives = 131/190 (68%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G+L SRKGVN P + L A++ KD+ DL FG ++GVD++ SF+ + + + R IL Sbjct: 140 NPGVLSSRKGVNFPHSNLRLSAITPKDEKDLRFGAKEGVDIVAISFVNSAQDIKKARSIL 199 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 ++ N I++KIE + + NL+ I+ SDG+MVARGDLGIE+ EKV + QK +I N Sbjct: 200 AQEEANPWIVAKIETKKAVENLESILQASDGVMVARGDLGIEVGIEKVPVIQKRIIKEAN 259 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 R+GKPVI ATQML SMV P PTRAE+SDVANA++DG+D VMLS ET G YPVE V T+ Sbjct: 260 RLGKPVITATQMLLSMVNSPFPTRAEVSDVANAVIDGSDAVMLSDETTVGKYPVEAVQTL 319 Query: 562 ANICKEAEAV 591 + E ++ Sbjct: 320 RKVIDETMSI 329 >UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Leptospira interrogans Length = 486 Score = 198 bits (483), Expect = 1e-49 Identities = 91/188 (48%), Positives = 134/188 (71%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G LGSRK +NLPGI V+LP+++ KD D+LFG+E+ VD I SF+R+ +++++ I+ Sbjct: 155 DGGRLGSRKHINLPGIRVNLPSITPKDHKDILFGLEEDVDFIALSFVRSVEDINQLKQII 214 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E + +II+KIE+ + + N+ EI+ +DG+MVARGDLG+E+P E++ + Q+ +I C Sbjct: 215 EENDGHAQIIAKIEDQEAVRNMKEIVEAADGVMVARGDLGVEVPIEELPILQRAIIKECA 274 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 GK VI AT +LESM+ P PTRAE++DVANAI + AD +MLSGETA G +P+ CV M Sbjct: 275 LKGKRVIVATHLLESMIHNPSPTRAEVTDVANAIYEEADAIMLSGETAAGKFPIRCVEMM 334 Query: 562 ANICKEAE 585 I + E Sbjct: 335 DKIAQRVE 342 >UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis ATCC BAA-548 Length = 357 Score = 198 bits (482), Expect = 1e-49 Identities = 99/186 (53%), Positives = 129/186 (69%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L + K VN+PG + +PA++ KD+ + + V+ +D I SF+R+ + +R IL Sbjct: 32 GELKNHKSVNVPGAELKMPALTRKDRDFIEYAVKNDLDFIAHSFVRSANDVLAVRSILDT 91 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +I+II+KIEN QG+ NLDEI+ +DG+MVARGDLGIEIP E+V L QK +I C Sbjct: 92 GDSDIRIIAKIENRQGVDNLDEILKAADGVMVARGDLGIEIPLEEVPLIQKKLIRACMAA 151 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GK VI ATQML+SM P PTRAEI+DVANA+ DG D VMLSGETA+G YPVE V M+ Sbjct: 152 GKSVITATQMLQSMENSPLPTRAEINDVANAVYDGTDAVMLSGETAEGVYPVEAVSVMSR 211 Query: 568 ICKEAE 585 I +E E Sbjct: 212 ILEETE 217 >UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep: Pyruvate kinase - Rhodopirellula baltica Length = 476 Score = 197 bits (481), Expect = 2e-49 Identities = 98/199 (49%), Positives = 134/199 (67%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L SR+ +NLPG+ V+LPA+++KD++DL GV+ G+D + SF+R + +R L E Sbjct: 157 GVLESRRHINLPGVQVNLPAITDKDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDE 216 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G +IISKIE+ G+ N+ II +SD IMVARGDLG+EI ++ L Q +I C Sbjct: 217 HGSPARIISKIEDQAGVRNMKAIIRQSDAIMVARGDLGVEIDYHRLPLVQTDLIRACQED 276 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI AT +LESM++ P PTRAE+SDV+NAI + AD VMLSGET G YP+E V + N Sbjct: 277 GKPVIIATHLLESMIQSPVPTRAEVSDVSNAIREQADAVMLSGETTTGKYPLESVGVLQN 336 Query: 568 ICKEAEAVIWHRQLFNDLV 624 I E + RQL + +V Sbjct: 337 IVASIEPTV-SRQLNSKIV 354 >UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 477 Score = 197 bits (480), Expect = 3e-49 Identities = 94/190 (49%), Positives = 131/190 (68%), Gaps = 1/190 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILG 204 G + S KG+N P + + ++EKD DL FG+E+ D + SF+R G + +++ + Sbjct: 150 GPVSSHKGLNFPDSSLSISGLTEKDLEDLRFGLEELRPDWVAISFVRTGEEVLDVKERIR 209 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 E G ++ +ISKIE H+ + N++E+I SDG+MVARGDL +E+ E+V + QK ++ARC R Sbjct: 210 ELGGDVPVISKIEKHEAIDNIEEVIEASDGVMVARGDLAVELSAERVPIEQKRIVARCRR 269 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 G+PVI ATQML+SM++ PRPTRAE+SDVANAI D D VMLSGETA G YP + V M Sbjct: 270 RGRPVIVATQMLDSMMRNPRPTRAEVSDVANAIFDRTDAVMLSGETAVGRYPTQSVMEMD 329 Query: 565 NICKEAEAVI 594 IC+ AE I Sbjct: 330 RICRAAEGAI 339 >UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber (strain DSM 13855) Length = 476 Score = 196 bits (478), Expect = 5e-49 Identities = 100/193 (51%), Positives = 130/193 (67%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L SRKGVNLP + P ++EKD DL G+E VD++ SF++ + + + + E Sbjct: 150 GPLRSRKGVNLPDLQASTPPMTEKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEE 209 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 GK +++KIE Q + N+DEI+ DGIMVARGDLGIE+P E+V QK +I + Sbjct: 210 TGKKTSVVAKIEKPQAVHNIDEILEVVDGIMVARGDLGIEMPMEEVPGTQKRLIRKSMEA 269 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KPVI ATQMLESMV+ PRPTRAE SDVANA+LDG+D VMLS ETA GD+PV V M Sbjct: 270 AKPVITATQMLESMVEDPRPTRAEASDVANAVLDGSDAVMLSAETAVGDHPVRVVEAMNQ 329 Query: 568 ICKEAEAVIWHRQ 606 I ++AE+ WH + Sbjct: 330 IIRQAES-YWHEE 341 >UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae bacterium TAV2 Length = 480 Score = 196 bits (478), Expect = 5e-49 Identities = 93/187 (49%), Positives = 128/187 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L SR+ +NLPG+ V+LP+++EKDK+DL G+ +G+D + SF+R A + +R +L Sbjct: 161 GELKSRRHINLPGVKVNLPSLTEKDKTDLAVGLIEGIDFVALSFVREAADIQLLRDVLHR 220 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 II+KIE+ + NLDEI+ +D +MVARGDLGIE P E++ + Q+ + C Sbjct: 221 YKSRAGIIAKIEDQSAIANLDEIVRTTDALMVARGDLGIECPFEELPIIQRRAVRMCFDY 280 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI AT MLESM+ P PTRAEI+DVANA+ + ADCVMLSGET G YP+ECV + Sbjct: 281 GKPVIIATHMLESMIASPMPTRAEITDVANAVYEKADCVMLSGETTIGRYPLECVQILDK 340 Query: 568 ICKEAEA 588 I + E+ Sbjct: 341 IARRIES 347 >UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: Pyruvate kinase - Anabaena sp. (strain PCC 7120) Length = 476 Score = 196 bits (477), Expect = 6e-49 Identities = 95/186 (51%), Positives = 127/186 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L +RKGVNLP + + +++EKD DL FG++ VD + SF+R+ L + ++ Sbjct: 148 GLLSTRKGVNLPATRLPVSSITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEA 207 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 GK I++I+KIE + + +D II +D IM+ARGDLG+E+P +V L QK +I RCN+ Sbjct: 208 AGKTIRVIAKIERPEAVEQIDSIIDVADAIMIARGDLGVEMPIHEVPLIQKDIIRRCNQA 267 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM+ P PTRAE +DVAN+ILDG D VMLSGETA G YPV V M + Sbjct: 268 GKPVITATQMLESMISAPDPTRAEATDVANSILDGTDAVMLSGETAVGQYPVAAVQVMHD 327 Query: 568 ICKEAE 585 I E Sbjct: 328 IAVTTE 333 >UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyruvate kinase - Anaeromyxobacter sp. Fw109-5 Length = 491 Score = 196 bits (477), Expect = 6e-49 Identities = 94/186 (50%), Positives = 128/186 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L KG+NLPG+ + A+SEKD++D+ FG+ GVD + SF+R+ + R + Sbjct: 154 GVLREHKGINLPGVALRAEALSEKDRADIAFGLAHGVDAVALSFVRSAEDIRACRDEMER 213 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G+ + +I+KIE + + +D II +DGIM+ARGDLG+EI PE+V L QK + R N Sbjct: 214 VGRVVPVIAKIEKPEALDAIDAIIEAADGIMIARGDLGVEILPERVPLLQKDICRRGNAA 273 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPV+ ATQMLESM++ PRPTRAE SDVANA+ DGAD VMLS E+A G +P+ V M Sbjct: 274 GKPVVIATQMLESMIEHPRPTRAEASDVANAVWDGADAVMLSAESASGRFPLNAVQMMDR 333 Query: 568 ICKEAE 585 I +EAE Sbjct: 334 IVREAE 339 >UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: Pyruvate kinase - Mesoplasma florum (Acholeplasma florum) Length = 478 Score = 194 bits (474), Expect = 1e-48 Identities = 102/206 (49%), Positives = 135/206 (65%), Gaps = 1/206 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N ++ + K VNLPG+ +P +++KD +D+ +GVEQGVD I ASF+ + + EIR IL Sbjct: 159 NNHLVKTNKRVNLPGVDFSMPFLAQKDINDIKYGVEQGVDYIAASFVNSAENVKEIRDIL 218 Query: 202 GE-KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E G +I+IISKIE+ G+ N+D II SDGIM+ARGDLG+EIP V +K MI +C Sbjct: 219 AEANGSDIQIISKIESQVGIDNIDAIIEASDGIMIARGDLGLEIPYYDVPYWEKIMIRKC 278 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 GK VI ATQMLE+M + P PTRAE++DV A GAD MLSGE+A GDYP V+T Sbjct: 279 REAGKVVIVATQMLETMTENPAPTRAEVTDVYFATELGADATMLSGESAAGDYPFITVNT 338 Query: 559 MANICKEAEAVIWHRQLFNDLVSEVK 636 MA I K AE + + + + K Sbjct: 339 MATINKRAEIEFYKKAYYQTQLENAK 364 >UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|Rep: Pyruvate kinase - Stigmatella aurantiaca DW4/3-1 Length = 481 Score = 194 bits (472), Expect = 2e-48 Identities = 98/186 (52%), Positives = 126/186 (67%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L KG+NLPG + +P ++EKD DL FG E GVD + SF+R +H+ R + + Sbjct: 163 GLLKDHKGLNLPGAAISVPTITEKDAEDLAFGQELGVDYVALSFVRTANDIHQARTHVSK 222 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +I+KIE Q + NL+ I +DG+MVARGDLG+E+P E++ QK M+A NR Sbjct: 223 L--KTPLIAKIEKPQALENLEAISEAADGVMVARGDLGVEMPLEQLPGIQKRMVAEVNRK 280 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G VI AT+MLESMV RPTRAE+SDVANAILDGAD VMLSGETA G YP++ TMA Sbjct: 281 GGLVIVATEMLESMVGNARPTRAEVSDVANAILDGADAVMLSGETAAGKYPIDAAATMAR 340 Query: 568 ICKEAE 585 I +E E Sbjct: 341 IVEETE 346 >UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Deinococcus radiodurans Length = 482 Score = 192 bits (469), Expect = 6e-48 Identities = 100/207 (48%), Positives = 130/207 (62%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L + KG+N+P + +PA+SEKD D+ FG GVD + SF+R+ L R L Sbjct: 152 GTLKNNKGINVPEADLTVPALSEKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLAR 211 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G K+++KIE Q + +I+ E DG+MVARGDLG+E+ PE+V QK +I C Sbjct: 212 FGSRAKLMAKIEKPQAVDRFADILKEVDGVMVARGDLGVEMRPEQVPTIQKRIIRMCREA 271 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM+ PRPTRAE SDVANAI DG D VMLS E+A G YPVE V M Sbjct: 272 GKPVITATQMLESMINLPRPTRAEASDVANAIYDGTDAVMLSAESAAGQYPVESVAMMDR 331 Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPID 648 I +EAEA ++ + +V + + D Sbjct: 332 IAREAEASELYQLMQRQVVMDTEQAQD 358 >UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organisms|Rep: Pyruvate kinase - Borrelia burgdorferi (Lyme disease spirochete) Length = 477 Score = 192 bits (469), Expect = 6e-48 Identities = 94/189 (49%), Positives = 130/189 (68%), Gaps = 1/189 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G + ++K +N PGI + L +V+EKDK + + VD I SF+R+ + +++ IL Sbjct: 142 NDGQIKNKKSINTPGISLKLQSVTEKDKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEIL 201 Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 G ++KIISKIEN +G+ N++EI S GIMVARGD+G+EIP E V +AQ + C Sbjct: 202 TASGNPDVKIISKIENQEGIDNIEEIAKASYGIMVARGDMGVEIPAEDVPIAQLKITQTC 261 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 + G PVI ATQML +M++ PRPTRAE+SD+ANAIL+G D +MLSGETA G YP+E V Sbjct: 262 IKYGIPVITATQMLHTMIENPRPTRAEVSDIANAILNGTDAIMLSGETAYGKYPIEAVKM 321 Query: 559 MANICKEAE 585 M +I K+ E Sbjct: 322 MTSIAKKVE 330 >UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia intracellularis (strain PHE/MN1-00) Length = 471 Score = 192 bits (468), Expect = 7e-48 Identities = 96/189 (50%), Positives = 133/189 (70%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G++ SRKG+ LPG + +PA++EKD+ DL G++ GVD + SF+++ + E + I+ Sbjct: 150 GIITSRKGLALPGKSIKVPAITEKDQKDLSDGLKLGVDAVAISFVQSAEDIIEAKRIIKA 209 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G +I +I+K+E + +L+EI+ E D IMVARGDLGIE P ++ QK +I CN+ Sbjct: 210 NGYDIPVIAKLERRNAIEHLEEILKEVDIIMVARGDLGIECPLPELPAIQKRIIRACNKA 269 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KPVI ATQML SMV P PTRAEI+DVANA+LDGADCVMLS ETA G++PVE V M + Sbjct: 270 SKPVIVATQMLLSMVSNPTPTRAEITDVANAVLDGADCVMLSEETAMGNHPVETVGFMRD 329 Query: 568 ICKEAEAVI 594 I +AE ++ Sbjct: 330 ITTKAEELM 338 >UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 492 Score = 191 bits (466), Expect = 1e-47 Identities = 98/187 (52%), Positives = 128/187 (68%), Gaps = 1/187 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L SRKGV P + P ++EKD +D FGV VDM+ SF+R+ + E+R L E Sbjct: 170 GQLRSRKGVIFPDSQLSFPLLNEKDATDARFGVFLDVDMVAMSFVRSATEIIEMRLRLAE 229 Query: 208 KG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 G KN II+KIE+H+G+ NLDEI+ +DG++VARGDLG+ +P EKV QK +I + N Sbjct: 230 WGQKNSFIIAKIEDHKGIDNLDEILQVADGVLVARGDLGVTLPREKVPNIQKAIIQKANA 289 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 G PVI ATQMLESM PTRAE++DV +A++ G+D VMLSGETA G YP++ V M Sbjct: 290 FGVPVITATQMLESMTHHDIPTRAEVNDVYHAVIGGSDAVMLSGETASGRYPIQAVQEMN 349 Query: 565 NICKEAE 585 IC+EAE Sbjct: 350 RICREAE 356 >UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio bacteriovorus Length = 495 Score = 191 bits (465), Expect = 2e-47 Identities = 91/186 (48%), Positives = 128/186 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L RKG+NLPG+ + + ++ KD DL FG+ VD I SF+R+ + ++R ++ Sbjct: 151 GILKDRKGMNLPGVNLPVDCMTPKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEA 210 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 N KI++KIE + + NL+EI SD +MVARGDL +E+ ++ QK +I+ CN++ Sbjct: 211 GNSNAKIVAKIEMVEAIENLEEICRLSDAVMVARGDLAVEVGQSRLPGYQKRIISVCNQL 270 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQML+SMV+ PRPTRAEI+DVANA+LDG D +MLS E+A G YP +C+ TM Sbjct: 271 GKPVITATQMLDSMVENPRPTRAEITDVANAVLDGTDALMLSAESASGKYPFKCIRTMHE 330 Query: 568 ICKEAE 585 I E E Sbjct: 331 IITEVE 336 >UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Pyruvate kinase - Desulfuromonas acetoxidans DSM 684 Length = 474 Score = 191 bits (465), Expect = 2e-47 Identities = 93/188 (49%), Positives = 127/188 (67%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G+ SRKGVN+P + +PA +EKD+ DL FG++QGVD++ SF+R L EIR +L Sbjct: 145 SGGVAYSRKGVNMPSSHLSIPAFTEKDRDDLRFGLQQGVDIVALSFVRGADDLKEIRTML 204 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E + K+++KIE Q + +++EI+ D +M+ARGDLG+E+P E+V + QK +I + Sbjct: 205 AEVPEAPKLVAKIEKPQAVAHIEEILDVVDVVMIARGDLGVEVPLEQVPVLQKQLIHKAR 264 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 GK VI ATQML SMV PRPTRAE +DVANAI DG D +MLS ETA GDYPV + Sbjct: 265 LKGKAVITATQMLSSMVSNPRPTRAEAADVANAIYDGTDALMLSDETASGDYPVAATRML 324 Query: 562 ANICKEAE 585 I + E Sbjct: 325 DRIARSTE 332 >UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: Pyruvate kinase - Mycoplasma mobile Length = 483 Score = 190 bits (464), Expect = 2e-47 Identities = 97/195 (49%), Positives = 138/195 (70%), Gaps = 1/195 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+ +L S K +N+PG + L +S+KDK D++FG++ V+ I ASF+ + + ++R +L Sbjct: 163 NSHVLKSNKRINIPGAQLSLEFLSKKDKEDIIFGIKNDVNYIAASFVNSKQDVLDLRKLL 222 Query: 202 GEK-GKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 + G++I+IISKIE+ G+ N+DEII SDGIM+ARGDLG+EIP +V +K +I +C Sbjct: 223 KDNNGEHIQIISKIESVFGIENIDEIIEASDGIMIARGDLGLEIPYFEVPFYEKQIIRKC 282 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 VGKPVI ATQML+SM K P+PTRAE+SDV A GAD MLSGE+A GD+PVE V Sbjct: 283 RNVGKPVIVATQMLDSMEKLPQPTRAEVSDVYWATELGADATMLSGESANGDFPVESVEV 342 Query: 559 MANICKEAEAVIWHR 603 M+ I + AE +++ Sbjct: 343 MSTINRRAEKEFYNK 357 >UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95 Length = 478 Score = 190 bits (464), Expect = 2e-47 Identities = 98/190 (51%), Positives = 126/190 (66%), Gaps = 1/190 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + R+G+N+PGI + LP ++EKD L VE VD I SF+R + R IL E Sbjct: 154 GSITHRRGINVPGIDISLPPLTEKDMEYLNKAVEWNVDYIAQSFVRKAEDITRTRRILTE 213 Query: 208 KGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 G ++ II+KIE Q + NL+ II E+DG+MVARGDLG+E P E++ L QK +I N Sbjct: 214 LGMPDLPIIAKIETLQALDNLESIIEEADGVMVARGDLGVEAPVEQIPLLQKRIIEIANT 273 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 + KP I ATQMLESMV P PTRAE +D+ANAILDG D VMLS ET+ G YP + V MA Sbjct: 274 MAKPAITATQMLESMVNNPFPTRAEATDIANAILDGTDAVMLSEETSIGKYPEQAVKVMA 333 Query: 565 NICKEAEAVI 594 N+ KE E ++ Sbjct: 334 NVAKETEKIL 343 >UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum lacusprofundi ATCC 49239 Length = 613 Score = 190 bits (462), Expect = 4e-47 Identities = 96/190 (50%), Positives = 127/190 (66%), Gaps = 1/190 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G L SRKGVNLPG+ +D+ ++ +D+++L D + ASF+RN ++ I L Sbjct: 170 SGGKLSSRKGVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRNANDVYRIADAL 229 Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E+G +I I++KIE + NLD II +DG+MVARGDLG+E P E V + QK +I +C Sbjct: 230 EERGGDDIPIVAKIERAGAVENLDGIIDAADGVMVARGDLGVECPLEDVPVIQKRIIRKC 289 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 G PVI AT+ML+SMV RPTRAE SDVANA+LDG D VMLSGETA GD PV V T Sbjct: 290 VNAGVPVITATEMLDSMVSSRRPTRAEASDVANAVLDGTDAVMLSGETAIGDDPVNVVET 349 Query: 559 MANICKEAEA 588 M I ++ E+ Sbjct: 350 MDRIVRQVES 359 >UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina mazei (Methanosarcina frisia) Length = 477 Score = 189 bits (461), Expect = 5e-47 Identities = 96/186 (51%), Positives = 121/186 (65%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S KG+NLPG + L AV+EKD L F +E+ +D SF+ N + ++R Sbjct: 152 GELYSHKGLNLPGAKIFLDAVTEKDFRILEFALEEDIDTFSISFVENAEDIRKVRNFAAS 211 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +GK + I+SKIE Q + N+ EI+ E+D +MVARGDLG+EIP ++V QK +I R + Sbjct: 212 RGKQVNIVSKIERRQAVENIGEILDETDALMVARGDLGVEIPIQEVPSVQKELIQRAKLL 271 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G PVI AT ML SM RPTRAE +DVANAILDG D VMLS ETA G+YPVE V MA Sbjct: 272 GVPVITATHMLASMTDNIRPTRAEATDVANAILDGTDAVMLSEETAVGNYPVEAVEMMAK 331 Query: 568 ICKEAE 585 I K E Sbjct: 332 IAKTTE 337 >UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep: Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis) Length = 482 Score = 189 bits (460), Expect = 7e-47 Identities = 95/188 (50%), Positives = 125/188 (66%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G L +RKGVN+PG +D+ ++ KD+ DL FG+E GVD + SF++ + E R ++ Sbjct: 152 NGGALSNRKGVNVPGAVLDISPLTAKDREDLEFGLELGVDWVALSFVQRARDMIEARSLV 211 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G++ +I+KIE + ++++I+ SD +MVARGDLG+EIPPE V QK +I C Sbjct: 212 GDRAG---LIAKIEKPSALDDIEDIVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACR 268 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 KPVI ATQML+SMV P PTRAE SDVA AI DGAD VMLS ETA G YPVE V M Sbjct: 269 LAAKPVIVATQMLDSMVSSPTPTRAEASDVAGAIYDGADAVMLSAETATGAYPVEAVEIM 328 Query: 562 ANICKEAE 585 I ++ E Sbjct: 329 NRIIEKTE 336 >UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacterium MLMS-1|Rep: Pyruvate kinase - delta proteobacterium MLMS-1 Length = 493 Score = 188 bits (459), Expect = 9e-47 Identities = 87/191 (45%), Positives = 130/191 (68%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192 Q + G+LGSR+ +N+ G DLPA++E+D +D+ FG+EQ VD I SF+R + ++ Sbjct: 157 QSLDEGVLGSRRHLNIRGKSADLPAITEQDWADIEFGMEQRVDFIALSFVRTAEPIQVVQ 216 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 L +G +++++KIE+ + LD IIA +DG+MVARGDLG E+P E+V L Q ++A Sbjct: 217 QHLAARGVTMEVMAKIESAASIAQLDAIIAAADGVMVARGDLGAELPYEEVPLLQDEIVA 276 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 +C R GKPV+ AT MLESM+ P PTRAE++D+ +A+ G+D +MLSGETA G YP + + Sbjct: 277 KCRRAGKPVVVATHMLESMIVNPTPTRAEVTDITHAVQQGSDAIMLSGETATGRYPYKAL 336 Query: 553 HTMANICKEAE 585 M + + E Sbjct: 337 EVMDAVARRIE 347 >UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase - uncultured delta proteobacterium DeepAnt-32C6 Length = 466 Score = 188 bits (457), Expect = 2e-46 Identities = 96/187 (51%), Positives = 126/187 (67%), Gaps = 1/187 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILG 204 GML RKG+N+PG + PA+++KDK DL F V+ GVD I SF+R A + E + + Sbjct: 148 GMLSERKGINVPGSALSTPALTDKDKRDLAFAVDTIGVDWIALSFVRTAADILEAKSL-- 205 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 KN +I+K+E + + NL I +DG MVARGDLG+E+ PEKV L QK +I N Sbjct: 206 --AKNTPVIAKLEKPEAIANLCAIADVADGAMVARGDLGVELGPEKVPLVQKRIIEEVNT 263 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 GK VI ATQML+SM++ PRPTRAE +D+ANA+LDG D +MLSGETA G YP++ V M Sbjct: 264 RGKLVITATQMLDSMIRNPRPTRAEAADIANAVLDGTDALMLSGETAVGRYPIKAVKMMD 323 Query: 565 NICKEAE 585 I +E E Sbjct: 324 VIIREVE 330 >UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain NBC37-1) Length = 488 Score = 188 bits (457), Expect = 2e-46 Identities = 94/189 (49%), Positives = 126/189 (66%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 +N GML SRKGVN P + + ++EKDK D+L+G++ VD + SF+++ + R + Sbjct: 150 ENNGMLSSRKGVNFPNTHLGINVLTEKDKKDILWGIKHEVDFMAISFVQHQKDMTAAREV 209 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 + G ++++++KIE + N+D I+ SDGIMVARGDLGIEIP V L QK +I R Sbjct: 210 ITSNGGSVQLLAKIEKFDAIENIDAILEASDGIMVARGDLGIEIPYYDVPLIQKMLIKRA 269 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N + KPVI ATQML SM K +RAEISDVANA+LDGAD VMLS E+A G YP+ V T Sbjct: 270 NNMSKPVIVATQMLLSMTTKVTASRAEISDVANAVLDGADAVMLSEESAIGHYPIRAVET 329 Query: 559 MANICKEAE 585 M + AE Sbjct: 330 MVQTIQSAE 338 >UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (class)|Rep: Pyruvate kinase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 475 Score = 186 bits (454), Expect = 4e-46 Identities = 92/186 (49%), Positives = 127/186 (68%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + + KGV+LPG+ + +PA+SEKD DL F ++ GVD I SF+R+ A + I+ E Sbjct: 149 GPVSNNKGVSLPGMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDE 208 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +G+ + +I+K+E + + +L+ I+ D +MVARGDLG+E+P E+V L QK I Sbjct: 209 EGRRVPVIAKLEKPEAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIAREN 268 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KPVI ATQML+SM++ RPTRAE SDVANA+LDGAD VMLSGET+ G P V TM+ Sbjct: 269 AKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSR 328 Query: 568 ICKEAE 585 I + AE Sbjct: 329 IVRFAE 334 >UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Pyruvate kinase - Mycobacterium tuberculosis Length = 472 Score = 186 bits (453), Expect = 5e-46 Identities = 89/181 (49%), Positives = 123/181 (67%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + KG++LPG+ V PA+SEKD DL F + GVDM+ SF+R+ A + + ++ Sbjct: 149 GPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDR 208 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G+ + +I+K+E + + NL+ I+ D +MVARGDLG+E+P E+V L QK I Sbjct: 209 IGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMAREN 268 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KPVI ATQML+SM++ RPTRAE SDVANA+LDGAD +MLSGET+ G YP+ V TM+ Sbjct: 269 AKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSR 328 Query: 568 I 570 I Sbjct: 329 I 329 >UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyruvate kinase - Acidobacteria bacterium (strain Ellin345) Length = 485 Score = 185 bits (450), Expect = 1e-45 Identities = 94/186 (50%), Positives = 120/186 (64%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L SRKG+NLPGI + + A +E D+ L F +E GVD + SF++N + +R Sbjct: 152 GELRSRKGLNLPGINLGISAFTEHDRDCLKFALENGVDAVSQSFVQNAHDIELVRTAAES 211 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G + I +KIE + + N DEI+ SDGIMVARGDLGIE+P E++ + QK +I+ N Sbjct: 212 LGHHPFIFAKIERAEAVQNYDEILRASDGIMVARGDLGIEVPMEEIAVIQKQLISGANAA 271 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM+ PTRAE +DVANAI DG DCVMLSGE A G +P E V + Sbjct: 272 GKPVITATQMLESMITNRLPTRAECTDVANAIFDGTDCVMLSGECAVGQFPEEAVAMLGK 331 Query: 568 ICKEAE 585 I E Sbjct: 332 IAAATE 337 >UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep: Pyruvate kinase - Flavobacteriales bacterium HTCC2170 Length = 480 Score = 184 bits (449), Expect = 1e-45 Identities = 88/187 (47%), Positives = 130/187 (69%), Gaps = 1/187 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S+KGVNLP + LPA++EKD D F + VD I SF+R+ + +++ I+ E Sbjct: 152 GPLKSKKGVNLPNTNISLPALTEKDVKDAKFAISLDVDWIALSFVRHSQDIIDLQNIIKE 211 Query: 208 KGKN-IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 ++ I II+KIE + + N+D+I++ DG+MVARGDLG+E+P +V L QK ++ R + Sbjct: 212 HAEHKIPIIAKIEKPEAVENIDKIVSYCDGLMVARGDLGVEVPAHEVPLIQKKLVLRAKK 271 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 PVI ATQM+E+M+ PTRAE++DVAN+++DGAD VMLSGET+ G+YPV+ + MA Sbjct: 272 ARIPVIIATQMMETMITSLTPTRAEVNDVANSVMDGADAVMLSGETSVGNYPVQVIEKMA 331 Query: 565 NICKEAE 585 +I + E Sbjct: 332 SILESVE 338 >UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep: Pyruvate kinase - Chlamydia trachomatis Length = 485 Score = 184 bits (448), Expect = 2e-45 Identities = 102/208 (49%), Positives = 133/208 (63%), Gaps = 3/208 (1%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+G + S K +++ I V LP ++EKD +DL FGVEQ +D+I ASF+R + +R +L Sbjct: 147 NSGEIKSNKSLSIKDIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVL 206 Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 G+ N+ II+KIENH G+ N EI +DGIM+ARGDLGIE+ +V QK M Sbjct: 207 ESFGRPNMPIIAKIENHLGVQNFQEIARAADGIMIARGDLGIELSIVEVPGLQKFMARAS 266 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 G+ I ATQMLESM++ P PTRAE+SDVANAI DG VMLSGETA G +PV V T Sbjct: 267 RETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHPVHAVKT 326 Query: 559 MANICKEAEAVIWHRQLF--NDLVSEVK 636 M +I +E E + F ND S +K Sbjct: 327 MRSIIQETEKTFDYHAFFQLNDKNSALK 354 >UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Pyruvate kinase - Monocercomonoides sp. PA203 Length = 516 Score = 184 bits (447), Expect = 3e-45 Identities = 97/191 (50%), Positives = 124/191 (64%), Gaps = 2/191 (1%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVD-LPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIR 192 + G + KG+NLP + LPA++EKD D F ++ VD SF+R + ++R Sbjct: 179 EQGGDVKDHKGINLPATDLGPLPALTEKDIEDAKFVLDTLEVDFFALSFVRKPQDVLDLR 238 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 ++ KGK ++II KIE + + NLDEI+A SD MVARGDL +E+ KV QK +I Sbjct: 239 HLIEAKGKEMRIIVKIEKPEAIKNLDEILAVSDACMVARGDLAVEVGTAKVPCLQKHIIR 298 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 C +G PVI ATQMLESM P PTRAE +DVANAI DG DCVMLSGETA G++PVE V Sbjct: 299 HCLEMGLPVITATQMLESMTHNPTPTRAEATDVANAIYDGTDCVMLSGETAAGEFPVETV 358 Query: 553 HTMANICKEAE 585 HTM +I E E Sbjct: 359 HTMQDIILETE 369 >UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium longum Length = 509 Score = 183 bits (446), Expect = 3e-45 Identities = 92/182 (50%), Positives = 120/182 (65%) Frame = +1 Query: 25 AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 204 AG + S KG+NLPG+ V LPA++EKD++DL + + G D+I SF+R + I+ Sbjct: 181 AGPVSSHKGINLPGVAVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMD 240 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 E+G+ I II+KIE Q + NL+EI+ DG+M ARGD+ +E P E+V LA K +I + Sbjct: 241 EEGRRIPIIAKIEKPQALENLEEIVKTFDGVMAARGDMAVECPLEEVPLATKRIIELARQ 300 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 KPVI AT++L SMV P PTRAE SD ANAILDG+D M S ETA G YP V TMA Sbjct: 301 YAKPVIVATEVLGSMVNSPVPTRAEASDCANAILDGSDATMTSNETAVGKYPDVTVATMA 360 Query: 565 NI 570 I Sbjct: 361 RI 362 >UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Pyruvate kinase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 477 Score = 183 bits (445), Expect = 5e-45 Identities = 91/189 (48%), Positives = 123/189 (65%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G + KG++LP IPV +P +S+KD DL F +E G DMI SF+R + I+ Sbjct: 148 DGGPVSDHKGISLPNIPVSVPPLSDKDIEDLKFALELGADMIAMSFVRAPEEVELAHKIM 207 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E G+ + +I+K+E + + +L I+ DG+MVARGDLG+E+P E++ L Q+ IA C Sbjct: 208 DEVGRRVPVIAKLEKPEAVSDLPAIVEAFDGLMVARGDLGVEMPLEQIPLVQRRAIALCR 267 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 + KPVI ATQML+SMV RPTRAE+SDVANA+ D AD VMLS ET+ G P V TM Sbjct: 268 QAAKPVIVATQMLDSMVSDRRPTRAEVSDVANAVFDRADAVMLSAETSVGADPAHAVATM 327 Query: 562 ANICKEAEA 588 A I AE+ Sbjct: 328 ARIVVAAES 336 >UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus group|Rep: Pyruvate kinase - Bacillus anthracis Length = 352 Score = 182 bits (444), Expect = 6e-45 Identities = 93/189 (49%), Positives = 127/189 (67%), Gaps = 1/189 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + S KGVNLPG V LPA++EKDK D+ F +E+ VD I SF+R + + EIR + + Sbjct: 143 GNISSHKGVNLPGAIVSLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQ 202 Query: 208 -KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 K + +I+KIE + + N +I E+DGIM+ARGDLG+E+P + + L QK MI CNR Sbjct: 203 YKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDLGVELPYQFIPLLQKMMIQECNR 262 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 VI ATQML+SMV PTRAE++DV A+LDG + VMLS E+A G++PVE V T+ Sbjct: 263 TNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPVESVSTLR 322 Query: 565 NICKEAEAV 591 + + AE V Sbjct: 323 LVSEFAEHV 331 >UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp. MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain MC-1) Length = 569 Score = 181 bits (441), Expect = 1e-44 Identities = 89/189 (47%), Positives = 124/189 (65%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 ++ G+L S KG+N+P + P+++ KD+ DL FGV+ VD + SF+R+ + ++ + Sbjct: 149 EHGGLLKSHKGINMPDASISAPSLTTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFM 208 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 L + II+KIE + + N+DEII DGIM+ARGD+ +EI +V Q+ +I +C Sbjct: 209 LHRRKIYKPIIAKIERPEAIRNIDEIIKVVDGIMIARGDMAVEIGNHRVPSVQRQIIQKC 268 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 GKPVI ATQMLESM++ P PTRAE SDVANAI DG D VMLS ET+ G P+ V T Sbjct: 269 RAKGKPVITATQMLESMIQNPSPTRAEASDVANAIWDGTDAVMLSAETSVGVDPINTVLT 328 Query: 559 MANICKEAE 585 M I +EAE Sbjct: 329 MGRIVEEAE 337 >UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep: Pyruvate kinase - Methylobacterium extorquens (Protomonas extorquens) Length = 483 Score = 181 bits (440), Expect = 2e-44 Identities = 93/192 (48%), Positives = 130/192 (67%), Gaps = 2/192 (1%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + +RKGV+LP + +PA++EKD+ DL G+ G D I SF++ + E++ + Sbjct: 156 GRISNRKGVSLPHTALPVPAMTEKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKVAA- 214 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 G+ + +++KIE Q + LDEII SDGIMVARGDLG+E+P E+V QK + R+ Sbjct: 215 -GRAL-VMAKIEKPQALTRLDEIIEISDGIMVARGDLGVEMPLEQVPGVQKRITRVARRL 272 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPV+ ATQMLESM+ P PTRAE+SDVA A+ +GAD VMLS E+A GD+PVE + TM Sbjct: 273 GKPVVVATQMLESMITSPVPTRAEVSDVATAVYEGADAVMLSAESAAGDFPVEAIGTMNR 332 Query: 568 ICKEAE--AVIW 597 I ++ E A+ W Sbjct: 333 IAEQVERDALYW 344 >UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep: Pyruvate kinase - Methanococcus jannaschii Length = 447 Score = 179 bits (435), Expect = 7e-44 Identities = 87/199 (43%), Positives = 126/199 (63%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + GVNLP ++LP + E D ++ F VE+ + I SF+RN + E++ I+ E Sbjct: 132 GEIKEGMGVNLPDTRIELPIIDETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISE 191 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + ++ISKIE +G+ N+ EI ESDG+MVARGDLG+E+P E + + QK ++ NR Sbjct: 192 YKGDCEVISKIETKEGLKNIKEIARESDGVMVARGDLGVEVPIENIPIEQKNILRIANRY 251 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G I ATQ+L+SM+ P PTRAE++D+ANAI DG DC+MLS ET G YP+E + + Sbjct: 252 GILSITATQILDSMINNPFPTRAEVTDIANAIYDGTDCLMLSNETTIGKYPIEAIKVLNK 311 Query: 568 ICKEAEAVIWHRQLFNDLV 624 + K A+ H + F D V Sbjct: 312 VAKVADE---HYEEFGDRV 327 >UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyruvate kinase - Chromobacterium violaceum Length = 468 Score = 178 bits (434), Expect = 1e-43 Identities = 87/186 (46%), Positives = 121/186 (65%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S KG NLP + L A++ KD+ D F +E+G D + SF++ A + +R I+G Sbjct: 148 GELSSNKGFNLPHTVLPLSAITGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIVG- 206 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 K + I++KIE + +L+ I +DG+MVARGDLG+E+PPE V + Q+ ++ C + Sbjct: 207 --KRVGIVAKIEKPSAVDDLEAIAELADGVMVARGDLGVELPPEDVPVVQRRIVHHCRHL 264 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G+PVI ATQMLESM+ P PTRAE +DVA A+ +GAD VMLS ETA G YP+E V M Sbjct: 265 GRPVIVATQMLESMITAPTPTRAEANDVATAVYEGADAVMLSAETAAGQYPLEAVQIMDR 324 Query: 568 ICKEAE 585 I + E Sbjct: 325 IIRRVE 330 >UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase - Candidatus Desulfococcus oleovorans Hxd3 Length = 478 Score = 177 bits (431), Expect = 2e-43 Identities = 84/191 (43%), Positives = 126/191 (65%) Frame = +1 Query: 13 QQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 192 + N+G++ S KG++ PG+ +DLPA++ KD+SD+ ++ G+D + SF++ + +++ Sbjct: 149 ETQNSGLVSSNKGISFPGLAIDLPALTAKDRSDVAAALDVGIDALALSFVQKSQDVVDLK 208 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 + G+ + +I KIE + + EI+AE+D IMVARGDLG+E + + QK +I Sbjct: 209 KEMEHHGRQVPVIVKIERMNAIDHFQEIVAEADVIMVARGDLGLECSLPALPVIQKRIID 268 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 C KPV+ ATQML SMV P PTRAE++DVANAI+DGAD VMLS ETA G+YPVE Sbjct: 269 MCAEHQKPVVVATQMLLSMVHNPLPTRAEVADVANAIMDGADAVMLSEETAVGEYPVEAA 328 Query: 553 HTMANICKEAE 585 +A + + E Sbjct: 329 GMLAQVAEHTE 339 >UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D Length = 507 Score = 177 bits (430), Expect = 3e-43 Identities = 92/208 (44%), Positives = 133/208 (63%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G L RKGVN+P + +PA++EKD DL F + GVD I SF++ + R I+ Sbjct: 164 DGGPLSDRKGVNVPDAVIPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVIAAREII 223 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G++ ++SKIE +++L++I+ SD +MVARGDLG+E+PPE+V QK ++ Sbjct: 224 GDRAG---LLSKIEKPAALLHLEDIVQASDALMVARGDLGVELPPERVPGVQKRILRMAR 280 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 + GKPV+ ATQMLESM++ P PTRAE SDVA+A+ DG D VMLS E+A G +PV V M Sbjct: 281 QHGKPVVVATQMLESMIEAPVPTRAEASDVASAVYDGTDAVMLSAESASGKHPVAAVSIM 340 Query: 562 ANICKEAEAVIWHRQLFNDLVSEVKPPI 645 I E E +R L + ++ +PP+ Sbjct: 341 NRIIAETERDPLYRNLID---AQHQPPL 365 >UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 579 Score = 176 bits (429), Expect = 4e-43 Identities = 88/191 (46%), Positives = 121/191 (63%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G L SR+ +N+ G LP+++EKD D+ FGVE VD SF+++ +HE++ L Sbjct: 254 DGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYL 313 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G +I +I KIE+ + NL II SDG MVARGDLG E+P E+V + Q+ +I C Sbjct: 314 QNSGADIHVIVKIESADSIPNLHSIITASDGAMVARGDLGAELPIEEVPILQEEIINLCR 373 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 +GK VI A MLESM+ P PTRAE+SD+A A+ +GAD VMLSGETA G +P++ M Sbjct: 374 SMGKAVIVAANMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLKAAGVM 433 Query: 562 ANICKEAEAVI 594 + EA I Sbjct: 434 HTVALRTEATI 444 >UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast precursor; n=58; Viridiplantae|Rep: Pyruvate kinase isozyme G, chloroplast precursor - Nicotiana tabacum (Common tobacco) Length = 562 Score = 176 bits (429), Expect = 4e-43 Identities = 88/189 (46%), Positives = 122/189 (64%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G L SR+ +N+ G LP+++EKD D+ FGV VD SF+++ +HE++ L Sbjct: 235 DGGELKSRRHLNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYL 294 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 +I +I KIE+ + NL II+ SDG MVARGDLG E+P E+V L Q+ +I RC Sbjct: 295 KSCNADIHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQ 354 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 + KPVI AT MLESM+ P PTRAE+SD++ A+ +GAD VMLSGETA G YP++ V M Sbjct: 355 SMQKPVIVATNMLESMIDHPTPTRAEVSDISIAVREGADAVMLSGETAHGKYPLKAVKVM 414 Query: 562 ANICKEAEA 588 + E+ Sbjct: 415 HIVALRTES 423 >UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1; unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown Length = 477 Score = 176 bits (428), Expect = 5e-43 Identities = 93/190 (48%), Positives = 126/190 (66%), Gaps = 2/190 (1%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 +AG + S KGVNLP + + + A+ + +K + F + +D I SF+++ + + + Sbjct: 146 SAGKISSHKGVNLPNVDLPVRAIGDYEKRCIDFAKKIDMDAISVSFVKDQRDVIDAKEYC 205 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 + II+KIE Q + N+DEI+ SDGIMVARGDLGIE P E + +AQK +I + N Sbjct: 206 NTIDYHPFIIAKIERPQALKNIDEILEASDGIMVARGDLGIETPIECIAMAQKHIIKKAN 265 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 GKPVI ATQMLESM++ PRPTRAE SDVANAILDG DC+M+S E+A G +P V T+ Sbjct: 266 LAGKPVITATQMLESMIESPRPTRAEASDVANAILDGTDCIMVSEESAIGKHPDLVVSTL 325 Query: 562 ANI--CKEAE 585 ANI C E E Sbjct: 326 ANIAACVEKE 335 >UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep: Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas pseudomallei) Length = 484 Score = 176 bits (428), Expect = 5e-43 Identities = 93/204 (45%), Positives = 124/204 (60%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G++ RKGV++P + +PA+S KD+ DL FG+ GVD + SF++ + + R ++G Sbjct: 159 GIVSDRKGVSVPDATLAIPALSAKDRDDLEFGLSLGVDWVALSFVQTAQDVRDARALIGA 218 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + I++KIE Q + N+ EI+ +D +MVARGDLG+E+ E V QK +I Sbjct: 219 RAA---IVAKIEKPQAVANIAEIVDAADAVMVARGDLGVEMSLEDVPSVQKQIIRLARAA 275 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQMLESM P PTRAE SDVA A+ DGAD VMLS E+A G YPVE V M Sbjct: 276 GKPVIVATQMLESMTLAPTPTRAEASDVAAAVYDGADAVMLSAESASGQYPVEAVDFMRK 335 Query: 568 ICKEAEAVIWHRQLFNDLVSEVKP 639 I EA QL +V+ P Sbjct: 336 IISTTEADPIQPQLMKAIVTAHAP 359 >UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae|Rep: Pyruvate kinase - Xylella fastidiosa Length = 501 Score = 175 bits (427), Expect = 7e-43 Identities = 93/188 (49%), Positives = 121/188 (64%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G+L RKG+N G + L A++++D+ + GVD I SF R+ +HE R I Sbjct: 165 NDGVLSDRKGLNKQGGGLSLGALTDRDRELIGIVSRMGVDFIAVSFCRHAEEMHEARRIA 224 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E G + ++SKIE + +VNL EI+A SD +MVARGDLG+EI ++ QK +I Sbjct: 225 RECGCDAALVSKIERAEAIVNLAEIVAASDVVMVARGDLGVEIGDAQLPGLQKKIIKEAL 284 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 K VI ATQML+SMV+ P PTRAE+ DVANA++DG D VMLS ETA GDYPV+ V M Sbjct: 285 LQNKVVITATQMLQSMVESPMPTRAEVLDVANAVIDGTDAVMLSAETATGDYPVKAVEAM 344 Query: 562 ANICKEAE 585 A IC AE Sbjct: 345 ARICLGAE 352 >UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep: Pyruvate kinase - Methanosarcina acetivorans Length = 489 Score = 175 bits (427), Expect = 7e-43 Identities = 90/186 (48%), Positives = 117/186 (62%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S KG+NLPG + L +V+E D L F + + VD + SF+ + ++R Sbjct: 164 GQLYSHKGLNLPGAKIYLDSVTEHDFKILEFALNEEVDAVSISFVEKAEDIRKVRNFAST 223 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 GK + ++SKIE Q + N++EI+ E+D +MVARGDLG+EIP ++V QK +I + Sbjct: 224 MGKPVYVVSKIERSQAVQNIEEILEETDALMVARGDLGVEIPIQEVPSVQKELIRSAKLL 283 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 PVI AT ML SM RPTRAE +DVANAILDG D VMLS ETA G+YPVE V MA Sbjct: 284 SIPVITATHMLASMTDNIRPTRAEATDVANAILDGTDAVMLSEETAVGNYPVETVEMMAK 343 Query: 568 ICKEAE 585 I K E Sbjct: 344 IAKTTE 349 >UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep: Pyruvate kinase - Magnetococcus sp. (strain MC-1) Length = 483 Score = 175 bits (426), Expect = 9e-43 Identities = 91/187 (48%), Positives = 119/187 (63%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L RKG+N+P + + A+++KD DL FG+E G+D SF++ L E R ++ Sbjct: 151 GILSDRKGLNVPAAMLPVKALTDKDLEDLEFGLELGIDWCALSFVQRPEDLREARKLIHG 210 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + +++KIE Q + NL+EI+ +DG+MVARGDLG+E PE+V QK +I C Sbjct: 211 RAA---LLAKIEKPQAVDNLEEIVKVADGVMVARGDLGVEYTPERVPAVQKRLIRMCREQ 267 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KPVI ATQMLESM+ P PTRAE SDVANAI DGAD VMLS ETA G Y V M Sbjct: 268 CKPVIVATQMLESMIDAPIPTRAEASDVANAIYDGADAVMLSAETAVGSYACNAVSVMDR 327 Query: 568 ICKEAEA 588 I + EA Sbjct: 328 IARVTEA 334 >UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula marina DSM 3645 Length = 490 Score = 175 bits (425), Expect = 1e-42 Identities = 82/189 (43%), Positives = 123/189 (65%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L SR+G+NLPG + + ++ +D+ + + E +D + SF+R + +++ +L Sbjct: 157 GILRSRQGINLPGTKLGVETITPRDRDHIRWAAETDLDYVSLSFVREADDIRQLKDLLQA 216 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +I+KIE + + NL+EI+ S+G+MVARGDLG+EI +V AQK ++ C R+ Sbjct: 217 HESRAMVIAKIEKREALDNLEEIVEVSNGVMVARGDLGVEIDVAEVAAAQKLIVKTCTRI 276 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G+PVI ATQML+SM K RPTRAE +DVANAILDGAD MLS ETA G++P+ + M Sbjct: 277 GRPVIVATQMLDSMTKNSRPTRAEATDVANAILDGADACMLSQETAVGEHPIVVIKMMNR 336 Query: 568 ICKEAEAVI 594 I E ++ Sbjct: 337 IMLATEKML 345 >UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans Length = 498 Score = 173 bits (422), Expect = 3e-42 Identities = 91/189 (48%), Positives = 123/189 (65%), Gaps = 1/189 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N +L K +NLP +P +S+KD++D++F ++ D I ASF+ G + EI+ IL Sbjct: 176 NTWILRENKRINLPDSNYSIPFMSDKDRNDIIFAIKNKFDYIAASFVNTGDNVREIKKIL 235 Query: 202 GEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 E G ++I+IISKIE G+ +LD+II ESD IMVARGDLG+E+P V +K +I C Sbjct: 236 KEHGGEHIQIISKIETMTGIKSLDDIIDESDSIMVARGDLGLEVPYYDVPTYEKYIIKDC 295 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 GK VI ATQML+S+ K +PTRAE++DV A+ G DC MLSGETA G YP+ V Sbjct: 296 RHKGKTVIVATQMLDSLETKIQPTRAEVTDVFFAVERGTDCTMLSGETANGMYPINAVEV 355 Query: 559 MANICKEAE 585 MA I +E Sbjct: 356 MAKIDVSSE 364 >UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 527 Score = 173 bits (420), Expect = 5e-42 Identities = 91/233 (39%), Positives = 139/233 (59%), Gaps = 3/233 (1%) Frame = +1 Query: 25 AGMLGSRKGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAALHEIRGIL 201 A + GS ++ + +DLP ++EKDK + +GV+ +D + S+ R+ + + R +L Sbjct: 183 ATLAGSLFTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREML 242 Query: 202 GEKG--KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 + G +I +KIEN +G+ + DEI+ E+DGI+++RG+LGI++PPEKVFL QK + + Sbjct: 243 KKLGDLSQTQIFAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYK 302 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 CN GKP + T++++SM RPTRAE +DVANA+LDG+D ++L ET +G YPVE + Sbjct: 303 CNMAGKPAV-LTRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETIS 361 Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIV 714 T+ IC EAE V F V V P+ K AS I+ Sbjct: 362 TVGRICAEAEKVFNQDLYFKKTVKYVGEPMTHLESIASSAVRAAIKVKASVII 414 >UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep: Pyruvate kinase - Vitis vinifera (Grape) Length = 621 Score = 171 bits (415), Expect = 2e-41 Identities = 84/171 (49%), Positives = 117/171 (68%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G L SR+ +N+ G LP++++KD D+ FGV+ VD SF+++ +HE++ L Sbjct: 310 DGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFVKDAEVVHELKDYL 369 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G +I +I KIE+ + NL II+ SDG MVARGDLG E+P E+V L Q+ +I RC+ Sbjct: 370 RSCGADIHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCH 429 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGD 534 + KPVI AT MLESM+ P PTRAE+SD+A A+ +GAD VMLSGETA G+ Sbjct: 430 SMQKPVIVATNMLESMINHPTPTRAEVSDIAIAVREGADAVMLSGETAHGN 480 >UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep: Pyruvate kinase - Thermotoga maritima Length = 466 Score = 169 bits (411), Expect = 6e-41 Identities = 81/186 (43%), Positives = 123/186 (66%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + R+GVN+P + + +++++D+ + G V+ SF+R + + + + + Sbjct: 148 GKITHRRGVNVPTADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRK 207 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 GK I +ISKIE + + L+EII SDGIMVARGDLG+EIP E+V + QK +I Sbjct: 208 HGKEIPVISKIETKKALERLEEIIKVSDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYY 267 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KPVI ATQ+LESM++ P PTRAE++D+ANAI DGAD ++L+ ETA G +P+E + ++ Sbjct: 268 SKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLEAIKVLSK 327 Query: 568 ICKEAE 585 + KEAE Sbjct: 328 VAKEAE 333 >UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM 8797 Length = 489 Score = 168 bits (408), Expect = 1e-40 Identities = 84/194 (43%), Positives = 129/194 (66%), Gaps = 2/194 (1%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 + G++ S++GVNLPG+ + P ++EKD SDL + VE G+D I SF+R+ + +++ Sbjct: 158 EREGIIRSKQGVNLPGVQLSTPCLTEKDLSDLAWAVEHGLDYIGLSFVRSADDIRQLKEE 217 Query: 199 LGEKGKNIK--IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 + + +++KIE + + ++++I+ +D +MVARGDLG+E+ E+V + QK +I Sbjct: 218 IEKLNPEDAPHVVAKIEKIEAVSDIEQILKLTDAVMVARGDLGVEVDIERVPIIQKRIIH 277 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 CN+ PVI ATQML+SM PTRAE SDVANA+LDG+D VMLSGETA G P+ V Sbjct: 278 LCNQYRVPVITATQMLDSMQFNTFPTRAEASDVANAVLDGSDAVMLSGETAVGVSPLAAV 337 Query: 553 HTMANICKEAEAVI 594 M+ I +EA ++ Sbjct: 338 EMMSRIVREAARIL 351 >UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep: Pyruvate kinase - Nosema bombycis Length = 441 Score = 168 bits (408), Expect = 1e-40 Identities = 83/189 (43%), Positives = 123/189 (65%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+ L + K +LPG+ + +DK D ++ +D++FASFI + + ++ ++ Sbjct: 144 NSHRLKNNKKASLPGLVFEDNESEARDKKDFEIILKHKIDVVFASFINSRKEVESLKKLI 203 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 G + ++ I SKIE +G+ N+DEII SDGIM+ARGDLG+E+ K+F QK + +C Sbjct: 204 GSE--DVLIFSKIETLRGVENIDEIIEVSDGIMIARGDLGVEMTASKMFSTQKKITIKCR 261 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 KPVICATQMLE+M++ P P+RAEI+DV NA+ D D ++LSGETA G +P V TM Sbjct: 262 EAKKPVICATQMLETMIQNPVPSRAEITDVGNAVFDQFDGLLLSGETAVGKFPTLTVRTM 321 Query: 562 ANICKEAEA 588 I ++AEA Sbjct: 322 RKIIEDAEA 330 >UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep: Pyruvate kinase - Thermoplasma acidophilum Length = 544 Score = 168 bits (408), Expect = 1e-40 Identities = 84/188 (44%), Positives = 121/188 (64%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G+L R VN+PG ++L ++++D++ + G+ GVD SF++ + +R + Sbjct: 131 NDGVLRDRSRVNIPGRFIELGTITDRDRAFIREGIADGVDFFALSFVQKSENVDSLRDFV 190 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 + G + IISKIE G+ N++EI+ SDGIMVARGDLG+E+P ++V LAQK +I + Sbjct: 191 IDSGGDQYIISKIETKSGLDNIEEIVKSSDGIMVARGDLGVELPLKEVVLAQKHIIKTAH 250 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 G I ATQ+LESMV PTRAEISD+ NAI+D AD +MLS E+A G YPV+ V T+ Sbjct: 251 EDGDFTIVATQVLESMVNNSSPTRAEISDITNAIIDNADALMLSEESAIGKYPVQAVRTL 310 Query: 562 ANICKEAE 585 + E Sbjct: 311 KEVSDYVE 318 >UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3 Length = 485 Score = 165 bits (401), Expect = 1e-39 Identities = 87/199 (43%), Positives = 124/199 (62%), Gaps = 5/199 (2%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+G L +RKG+NL G + PA++ KD D+ D + SF RN +H R Sbjct: 150 NSGKLSNRKGINLLGGGLSAPALTPKDIEDMSTAALLNADFLAISFPRNAQDIHYARKKA 209 Query: 202 GEKGKNIKIISKIENHQGMVN---LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 E G +++II+K+E + + + +DE+I +D IMVARGDLG+EI ++ QK +I+ Sbjct: 210 KEAGCDVQIIAKVERAEVVASEKAMDEMIQAADIIMVARGDLGVEIGDARLARIQKQLIS 269 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 R KPVI ATQM+ESM++ P PTRAE+ D+ANA++DG+D +MLS E+A G YPVE V Sbjct: 270 RSKYFAKPVITATQMMESMIENPMPTRAEVLDIANAVMDGSDAIMLSAESAAGRYPVEAV 329 Query: 553 HTMANICKEAEA--VIWHR 603 M I AE V+ H+ Sbjct: 330 QAMVRIAAGAEEPNVVMHK 348 >UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacteria|Rep: Pyruvate kinase II - Salmonella typhimurium Length = 480 Score = 164 bits (399), Expect = 2e-39 Identities = 87/198 (43%), Positives = 122/198 (61%), Gaps = 3/198 (1%) Frame = +1 Query: 7 FEQQDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHE 186 F + G L + KG+N G + A++EKDK+D+ GVD + SF R G L+ Sbjct: 147 FTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNY 206 Query: 187 IRGILGEKGKNIKIISKIENHQGMVN---LDEIIAESDGIMVARGDLGIEIPPEKVFLAQ 357 R + + G + KI++K+E + + + +D+II SD +MVARGDLG+EI ++ Q Sbjct: 207 ARRLARDAGCDAKIVAKVERAEAVCDQNAMDDIILASDVVMVARGDLGVEIGDPELVGIQ 266 Query: 358 KTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDY 537 K +I R ++ + VI ATQM+ESM+ P PTRAE+ DVANA+LDG D VMLS ETA G Y Sbjct: 267 KALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQY 326 Query: 538 PVECVHTMANICKEAEAV 591 P E V MA +C AE + Sbjct: 327 PSETVAAMARVCLGAEKI 344 >UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteobacteria|Rep: Pyruvate kinase family - Nitrosomonas europaea Length = 496 Score = 164 bits (398), Expect = 2e-39 Identities = 84/186 (45%), Positives = 113/186 (60%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L + KG+N G + PA++ KD D+ D + SF R+G + R ++ E Sbjct: 149 GILSNNKGINRKGGGLSAPALTAKDLLDIKTSAVIRADYLAVSFPRSGDDIRRARALMQE 208 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + +++KIE + ++ LD+I+ SD IMVARGDL +E+ V QK MI Sbjct: 209 AQGHSLLMAKIERSEAILALDDILEASDAIMVARGDLAVEVGDAAVPALQKRMIRSAREA 268 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 K VI ATQM+ESM+ P PTRAE+SDVANA+LDG D VMLS E+A G YPVE V MA Sbjct: 269 NKLVITATQMMESMISNPIPTRAEVSDVANAVLDGTDAVMLSAESAAGQYPVEAVEAMAR 328 Query: 568 ICKEAE 585 +C EAE Sbjct: 329 VCLEAE 334 >UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organisms|Rep: Pyruvate kinase - Phaeodactylum tricornutum Length = 665 Score = 163 bits (396), Expect = 4e-39 Identities = 91/195 (46%), Positives = 120/195 (61%), Gaps = 6/195 (3%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 D AGM+ RKGVN P +++ ++ KD+SDL + + GVD + SF++ A + EI + Sbjct: 297 DVAGMIKDRKGVNTPDSVLEISPLTPKDRSDLEYMLGIGVDWVALSFVQTPADMVEIHAL 356 Query: 199 LGEK---GK-NIKIISKIENHQGMV--NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQK 360 + EK G+ +++KIE NL I+ +GIMVARGDLG+E PPE V L QK Sbjct: 357 IDEKLPSGQFKPAVMAKIEKPSCFYDDNLQRIVGLCNGIMVARGDLGVECPPEDVPLLQK 416 Query: 361 TMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540 +I C G+PVI ATQMLESM++ P PTRAE SDVA AI DGAD +MLS E+A G +P Sbjct: 417 EIIDECRNQGRPVIVATQMLESMIEVPTPTRAEASDVATAIYDGADAIMLSAESAAGKFP 476 Query: 541 VECVHTMANICKEAE 585 E V I E Sbjct: 477 EESVAMQQRIINRVE 491 >UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pneumophila|Rep: Pyruvate kinase II - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 474 Score = 161 bits (392), Expect = 1e-38 Identities = 85/187 (45%), Positives = 121/187 (64%), Gaps = 1/187 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L KG+N G + ++EKD++DL +E VD I SF+++ + + R ++ + Sbjct: 150 GVLTDLKGLNRKGGGLAARTLTEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKD 209 Query: 208 KGKNIK-IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 G I II+KIE + + +L +II E+D IMVARGDLG+E+ +V QK +I + Sbjct: 210 YGAQITPIIAKIERMEALDHLTDIIREADAIMVARGDLGVEVGAAEVPAIQKHIIEQTRL 269 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 + K VI ATQM+ESM+ P+PTRAE+SDVANAILDG D VMLS ETA G +PV+ + + Sbjct: 270 LDKVVITATQMMESMISNPQPTRAEVSDVANAILDGTDAVMLSAETASGLFPVKVITMVN 329 Query: 565 NICKEAE 585 IC AE Sbjct: 330 KICLSAE 336 >UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium (strain ATCC 15444) Length = 474 Score = 161 bits (392), Expect = 1e-38 Identities = 81/203 (39%), Positives = 127/203 (62%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G LG +KG + G + + A++EKD++DL F +E GVD++ SF++ + E++ I+ Sbjct: 154 GKLGDKKGFTVRGKALPVRALTEKDRADLDFALEIGVDIVALSFVQTVEDVEEVKAIIAG 213 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + +++K+E +++L+ I+A +D +MVARGDLG+E PE+V + Q+ ++ + Sbjct: 214 RAP---LVAKLEKPAAIIHLEAIVAAADAVMVARGDLGVEFAPEEVPVIQRRIVRVARAL 270 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 G+PVI ATQMLESM++ PTRAE SDVA AI GAD VMLS ETA G +P V M+ Sbjct: 271 GRPVIVATQMLESMIENSAPTRAEASDVATAIYQGADAVMLSAETAVGRHPATAVAIMSR 330 Query: 568 ICKEAEAVIWHRQLFNDLVSEVK 636 I + E +R+ + E + Sbjct: 331 IIRATEGADDYRRSLAEFCGEAQ 353 >UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain Hrk 5) Length = 464 Score = 161 bits (390), Expect = 2e-38 Identities = 82/187 (43%), Positives = 121/187 (64%), Gaps = 1/187 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + RK V + G + LP ++EKD D+ F V+ G D I SF+R+ + + +R IL + Sbjct: 145 GEVKPRKTVTVRGKDIPLPTITEKDLRDIEFSVKAGFDAIALSFVRSSSDVQRLRDILFD 204 Query: 208 KG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 G +++KII+KIE + +LD I+ +SD +VARGDL E+++ Q+ +I+R R Sbjct: 205 YGAEDVKIIAKIETKSAVEDLDSILQKSDAALVARGDLANFYGLEEIYSIQRYIISRARR 264 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 GKP I ATQ+LESM+ P PTR+E+ DV A+ GAD ++L+GETA G YPVE V+ + Sbjct: 265 FGKPSIVATQLLESMISNPLPTRSEVVDVITAVRMGADALLLAGETAAGKYPVESVYWLR 324 Query: 565 NICKEAE 585 I +EAE Sbjct: 325 RIVEEAE 331 >UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: Pyruvate kinase - Mycoplasma pneumoniae Length = 508 Score = 159 bits (386), Expect = 6e-38 Identities = 86/200 (43%), Positives = 123/200 (61%), Gaps = 1/200 (0%) Frame = +1 Query: 40 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-K 216 ++K +NLP +P +S KD D+ FG+ +D I ASF+ + ++R L K K Sbjct: 183 TKKRLNLPNADYSIPFLSAKDLRDIDFGLTHQIDYIAASFVNTTENIKQLRDYLASKNAK 242 Query: 217 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 396 ++K+I+KIE++ + N+D II SDGIMVARGDLG+EIP KV Q+ MI C K Sbjct: 243 HVKLIAKIESNHALNNIDGIIKASDGIMVARGDLGLEIPYYKVPYWQRYMIKACRFFNKR 302 Query: 397 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 576 VI ATQML+S+ K +PTRAE++DV A+ G D MLSGETA G +P+ V+ M I K Sbjct: 303 VITATQMLDSLEKNIQPTRAEVTDVYFAVDRGNDATMLSGETANGAFPLNAVYVMKMIDK 362 Query: 577 EAEAVIWHRQLFNDLVSEVK 636 ++E ++ N ++ K Sbjct: 363 QSETFFDYQYNLNYYMANSK 382 >UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus torridus Length = 555 Score = 157 bits (381), Expect = 3e-37 Identities = 79/183 (43%), Positives = 120/183 (65%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 ++G L VN+PG + L +++++D+ + G++ V+ SF+++ ++E++ L Sbjct: 143 DSGSLRDNSRVNVPGKLLRLGSLTDRDRMFIEEGIKNNVNFYALSFVQSRENINELQDYL 202 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 E+ + ++ISKIE G N+DEI SD IMVARGDLG+E+P ++V +AQK +I Sbjct: 203 FERNCDAQLISKIETKSGYDNIDEIARASDFIMVARGDLGVEMPLKEVTIAQKKIIDESR 262 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 + P I ATQMLESMV PTRAE+SD+ NAI+DG D +MLS ETA G YPVE + + Sbjct: 263 KYATPTIVATQMLESMVNNDSPTRAEVSDITNAIIDGTDALMLSEETAIGRYPVEAIGYL 322 Query: 562 ANI 570 ++I Sbjct: 323 SSI 325 >UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr3 scaffold_95, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 573 Score = 156 bits (378), Expect = 6e-37 Identities = 80/180 (44%), Positives = 123/180 (68%), Gaps = 3/180 (1%) Frame = +1 Query: 76 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQ 252 +LP +S KD +D+ FG+ +GVD I SF+++ A+ +++ L K K+I +++KIE+ + Sbjct: 258 ELPTISTKDWADIEFGISEGVDFIAMSFVKDANAIKQLKSYLSNKSSKSIGVLAKIESLE 317 Query: 253 GMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 432 + +L+EII SDGIMVARGDLG+EIP E++ + Q + C ++ +PVI A+Q+LESMV Sbjct: 318 SLQHLEEIIEASDGIMVARGDLGVEIPLEQIPVVQAKITHVCRQLNRPVIVASQLLESMV 377 Query: 433 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVE--CVHTMANICKEAEAVIWHRQ 606 + P PTRAE++DV+ A+ AD +MLSGE+A G Y + CV MA+ E +W R+ Sbjct: 378 EYPTPTRAEVADVSEAVRQYADALMLSGESAIGSYGQKALCVLRMASSRME----LWSRE 433 >UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep: Pyruvate kinase - Sulfolobus solfataricus Length = 452 Score = 154 bits (374), Expect = 2e-36 Identities = 81/194 (41%), Positives = 121/194 (62%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+L SRKG+N+P + + +++ D L ++ G D I SF+ + + +++ +G+ Sbjct: 134 GILLSRKGINIPNVNLK-SGITDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGD 192 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + +I+KIE + + NL I+ ESDGIMVARGDLG+E E + L Q+ ++ Sbjct: 193 EAW---VIAKIEKSEALKNLTNIVNESDGIMVARGDLGVETGLENLPLIQRRIVRTSRVF 249 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPVI ATQ+L SM+ P PTRAEI D++N+I+ G D +MLS ETA G+YPVE V T+ N Sbjct: 250 GKPVILATQVLTSMINSPIPTRAEIIDISNSIMQGVDSIMLSDETAIGNYPVESVRTLHN 309 Query: 568 ICKEAEAVIWHRQL 609 I E + HR + Sbjct: 310 IISNVEKSVKHRPI 323 >UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 500 Score = 154 bits (374), Expect = 2e-36 Identities = 84/200 (42%), Positives = 121/200 (60%), Gaps = 1/200 (0%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G + GV +PG D+P + + G D I SF+ + + + R +L Sbjct: 174 SGGTIREGMGVVIPGRRPDVPYAGARFIDYIRQGAALRPDYIALSFVGSAEDIRDARTLL 233 Query: 202 GEKGK-NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 +G NI +I+KIE + + LD+II +D +MVARGDLG+E+P E+V QK +I C Sbjct: 234 TREGMGNIPLIAKIECRRAVEGLDDIIRHADAVMVARGDLGVELPLEEVPYIQKLIITTC 293 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 ++ G PVI AT+MLESMV + RPTRAE++DVANAI+DG D MLS ET+ G YP + V Sbjct: 294 SQQGIPVITATEMLESMVSRGRPTRAEVTDVANAIVDGTDATMLSAETSVGRYPGQAVVM 353 Query: 559 MANICKEAEAVIWHRQLFND 618 MA I E E + + ++ N+ Sbjct: 354 MARIAIEIEQHLPYLRILNE 373 >UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas eutropha (strain C71) Length = 483 Score = 154 bits (373), Expect = 2e-36 Identities = 87/210 (41%), Positives = 126/210 (60%), Gaps = 1/210 (0%) Frame = +1 Query: 25 AGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 204 +G + S G+N+P + ++ D+ L+F +EQ + I SF+++ L +R +L Sbjct: 159 SGTVTSGSGINVPESKRSVLIPTDDDRRHLVFALEQQAEWIGVSFVQSADDLIRVRTLL- 217 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 G+ +++KIE Q +V+LD I+A SDG+MVARGDLG+E ++ L QK +IA N Sbjct: 218 PPGQQPLLMAKIEKRQALVDLDAIMATSDGVMVARGDLGVETDLAEIPLVQKRIIALANA 277 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 +PVI ATQMLESMV + +PTRAE++DVANA+LDG D VMLS ETA G +PV + Sbjct: 278 QARPVITATQMLESMVTQEQPTRAEVTDVANAMLDGTDGVMLSAETAIGRFPVAAAEILQ 337 Query: 565 NICKEAEAVIWHRQLFNDL-VSEVKPPIDP 651 + E R + L SE P +P Sbjct: 338 RVLTATETEYAVRVARDRLRASESTPATNP 367 >UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep: Pyruvate kinase - Oryza sativa subsp. japonica (Rice) Length = 548 Score = 153 bits (371), Expect = 4e-36 Identities = 76/177 (42%), Positives = 118/177 (66%), Gaps = 1/177 (0%) Frame = +1 Query: 79 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQG 255 LP +S KD +D+ FG+ +GVD I SF+++ + ++ L K ++IKI +K+E+ + Sbjct: 232 LPTLSAKDWADIEFGIAEGVDCIALSFVKDANDIKYLKTYLSRKSLEHIKIFAKVESLES 291 Query: 256 MVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVK 435 + NL +II SDG+MVARGDLG++IP E++ Q+ ++ C R+ KPVI A+Q+LESMV+ Sbjct: 292 LKNLKDIIEASDGVMVARGDLGVQIPLEQIPAIQEAIVDLCRRLNKPVIVASQLLESMVE 351 Query: 436 KPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQ 606 P PTRAE++DV+ A+ AD VMLS E+A G YP + + + + E+ W R+ Sbjct: 352 YPTPTRAEVADVSEAVRQYADAVMLSAESAIGAYPQKALAVLRAASERMES--WSRE 406 >UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter eiseniae (strain EF01-2) Length = 496 Score = 150 bits (364), Expect = 3e-35 Identities = 86/196 (43%), Positives = 112/196 (57%), Gaps = 4/196 (2%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-- 201 G L + KG+N G + A++ KD D+ + D + SF +N + R + Sbjct: 170 GELSNNKGINKKGGGLTASALTAKDMEDIRTAMGFQADYVAVSFPKNATDMEMARQLCTV 229 Query: 202 --GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 E+ +I+KIE + + +L I+ SDGIMVARGDL +E+ V QK MI Sbjct: 230 AASEQRHKPGLIAKIERAEAIPHLQAILRVSDGIMVARGDLAVEVGNAAVPALQKKMIRM 289 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 + K VI ATQM+ESM+ P PTRAE+SDVANA+LDG D VMLS ETA G YP+E V Sbjct: 290 ARDMDKLVITATQMMESMITNPVPTRAEVSDVANAVLDGTDAVMLSAETAAGRYPLETVT 349 Query: 556 TMANICKEAEAVIWHR 603 MA IC AEA HR Sbjct: 350 EMATICAAAEAAEEHR 365 >UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase isozyme A, chloroplast precursor - Nicotiana tabacum (Common tobacco) Length = 593 Score = 149 bits (360), Expect = 9e-35 Identities = 71/184 (38%), Positives = 119/184 (64%), Gaps = 2/184 (1%) Frame = +1 Query: 79 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN--IKIISKIENHQ 252 LP +S KD D+ FG+ +GVD I SF+++ + ++ + + ++ I +I+KIE+ Sbjct: 287 LPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESID 346 Query: 253 GMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 432 + NL+EII SDG MVARGDLG +IP E+V Q+ ++ C ++ +PVI A+Q+LESM+ Sbjct: 347 SLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLESMI 406 Query: 433 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF 612 + P PTRAE++DV+ A+ D +MLSGE+A G +P + + + ++ E +W Q Sbjct: 407 EYPIPTRAEVADVSEAVRQRGDALMLSGESAMGQFPEKALTVLRSVSLRIER-MWREQKR 465 Query: 613 NDLV 624 ++++ Sbjct: 466 HEVI 469 >UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon GZfos3D4 Length = 588 Score = 146 bits (354), Expect = 5e-34 Identities = 73/132 (55%), Positives = 89/132 (67%) Frame = +1 Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405 +I+KIE Q N+DEII +DGIMVARGDLG+++ P++V QK +I CN GKPVI Sbjct: 256 VIAKIETKQAWRNIDEIIDVADGIMVARGDLGLQVDPQEVPSIQKKIIKLCNLRGKPVIT 315 Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585 AT+ML SM P PTRAE +DV NAILDG D VMLSGET+ G YP V M NI ++AE Sbjct: 316 ATEMLSSMENNPEPTRAESTDVFNAILDGTDAVMLSGETSSGKYPAHAVRMMVNIAEQAE 375 Query: 586 AVIWHRQLFNDL 621 + L DL Sbjct: 376 EYFEQKGLSTDL 387 >UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 466 Score = 144 bits (349), Expect = 2e-33 Identities = 76/185 (41%), Positives = 113/185 (61%) Frame = +1 Query: 40 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 219 SRK + + G LP +S++D + F ++ G D I S +R + +R I+ +G + Sbjct: 155 SRKAIAIRGKDPGLPTLSQRDVEHVKFALDNGFDYIALSHVRTRDDVDALRLIVLREGGD 214 Query: 220 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPV 399 I KIEN + NL +II +D ++VARGDLG+ E+V + Q+ ++A VGKPV Sbjct: 215 AGIAVKIENKSAVENLQDIIRAADLVVVARGDLGMTYGLEEVPVLQERIVAAARSVGKPV 274 Query: 400 ICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKE 579 I ATQ+LESM++ P PTRAE++DV A+ G D +ML+GETA G YP+E + + I Sbjct: 275 IVATQLLESMIENPVPTRAEVTDVYVAVRQGVDGLMLTGETAIGRYPIEAIRWLRKIITR 334 Query: 580 AEAVI 594 AE V+ Sbjct: 335 AEQVL 339 >UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|Rep: Pyruvate kinase - Aeropyrum pernix Length = 458 Score = 143 bits (347), Expect = 3e-33 Identities = 74/186 (39%), Positives = 114/186 (61%), Gaps = 1/186 (0%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G+LG RKGV + G DLP +S KD+ L F ++GV ++ SF R+ + ++R ++ Sbjct: 142 GVLGPRKGVVVRGKEPDLPPLSAKDRRALEFFADKGVSHVYVSFARSAEHVEKVRTVVRR 201 Query: 208 KG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 G + +I +KIE G+ + EI SDG+++ARGDLG+ E++ Q+ ++ + Sbjct: 202 LGLRQARIFAKIEGPSGVSRIGEIAEASDGVIIARGDLGMHYSLEELPEIQELIVWEARK 261 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 K V+ AT+ L SM++KP PTR+E+ D+ A+L AD +ML+GETA G YPV+ V MA Sbjct: 262 RYKTVVLATEFLSSMIEKPVPTRSEVVDIYQAVLQTADALMLTGETAIGKYPVKSVQWMA 321 Query: 565 NICKEA 582 I A Sbjct: 322 KISSRA 327 >UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum|Rep: Pyruvate kinase - Ureaplasma parvum (Ureaplasma urealyticum biotype 1) Length = 474 Score = 140 bits (340), Expect = 2e-32 Identities = 75/188 (39%), Positives = 113/188 (60%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N+ L + K +NLP LP +S+KD D+ V+ + + SFI N ++E++ +L Sbjct: 173 NSYSLKTNKRLNLPDANYSLPFLSKKDIDDINLAVKLKIPYLALSFISNIKQINEVKQLL 232 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 + K+I+KIE + + NL+EII +DGIMVARGDLG+E+P K+ + Q ++ C+ Sbjct: 233 KKSSFIPKLIAKIETQEAIDNLEEIIKNTDGIMVARGDLGLEVPFYKIPIYQNKIVELCH 292 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 + K I ATQML+S+ + PTRAE++DV A+ + MLSGETA G P+ V M Sbjct: 293 KYNKYCIIATQMLDSLERNIIPTRAEVTDVYYAVKQKVNATMLSGETAAGIDPINAVQVM 352 Query: 562 ANICKEAE 585 +I E E Sbjct: 353 KSIILETE 360 >UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus marinus F1|Rep: Pyruvate kinase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 469 Score = 137 bits (331), Expect = 3e-31 Identities = 74/196 (37%), Positives = 115/196 (58%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N +L K + + G +DLP +SEKD + + V + + + SF+R + + +R I+ Sbjct: 144 NDAVLYPHKTLVVFGKEIDLPVLSEKDVDLVNYSVSRKLTYLAISFVRRSSDIVIVRDIV 203 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 I +I+KIE + NL +I++ SD I++ARGDLG+ E++ Q+ + Sbjct: 204 SRLNGEIGLIAKIETRSAVKNLKDIMSVSDAIIIARGDLGMHYSLEELPGLQRKIAREAI 263 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 +GKP I ATQ+LESMV PRP+R+E+ DV NA+ D D ++L+ ETA G YPVE V + Sbjct: 264 MIGKPSIVATQLLESMVNYPRPSRSEVVDVVNAVYDLVDALLLTDETAIGKYPVESVKWL 323 Query: 562 ANICKEAEAVIWHRQL 609 I AE+ I R++ Sbjct: 324 KRIISSAESSIVERRI 339 >UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Pyruvate kinase, barrel domain containing protein - Tetrahymena thermophila SB210 Length = 747 Score = 132 bits (320), Expect = 6e-30 Identities = 62/182 (34%), Positives = 114/182 (62%) Frame = +1 Query: 88 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267 ++ KD +D+ + +D I S +R+ + +R ++GE + ++I++KI+ + + N Sbjct: 439 ITPKDITDINHCINNDIDCICVSNVRSARDIKAVRNLIGED-RGVRIMAKIQTPESVENF 497 Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447 +EI+ SDG+ +ARG L + +P EK+F QK MI +C+ KPV+ + +L+SMV P Sbjct: 498 EEIVKASDGVQIARGYLTVHMPVEKLFAKQKEMIHKCHEHLKPVLVSCNILDSMVSSLLP 557 Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 627 T E+ +++N + D D ++LS ET+ G++PV+ + T++ IC EAEA+ ++L N S Sbjct: 558 TMCEVGEISNLVNDYVDNIVLSSETSCGNHPVQAIKTLSRICVEAEALRIMKRLQNPSHS 617 Query: 628 EV 633 ++ Sbjct: 618 DI 619 >UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: Pyruvate kinase - Plasmodium falciparum (isolate 3D7) Length = 745 Score = 128 bits (309), Expect = 1e-28 Identities = 67/123 (54%), Positives = 82/123 (66%), Gaps = 1/123 (0%) Frame = +1 Query: 220 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN-RVGKP 396 I IISKIE + N++ II SDGIM+ARGDLGIE + + QK +I C + KP Sbjct: 442 IAIISKIEKPSAIKNIENIIKLSDGIMIARGDLGIETNLSNLPILQKKLINLCRIKYNKP 501 Query: 397 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 576 VI ATQM+ESM P PTRAE++DVA A+ DG+DCVMLS ETA G YP+ V T I K Sbjct: 502 VIVATQMMESMRFLPSPTRAEVTDVATALYDGSDCVMLSAETATGQYPILTVSTQNKIIK 561 Query: 577 EAE 585 + E Sbjct: 562 DVE 564 Score = 40.7 bits (91), Expect = 0.036 Identities = 20/60 (33%), Positives = 35/60 (58%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L S+KG +P + + + +SEKD D+LF + + VD + SF++ L +R I+ + Sbjct: 259 GKLYSKKGFCIPNMIMPIDVLSEKDIKDILFCINEEVDFLGYSFVQTEYDLIFLRNIIND 318 >UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Pyruvate kinase, barrel domain containing protein - Tetrahymena thermophila SB210 Length = 837 Score = 126 bits (305), Expect = 4e-28 Identities = 64/184 (34%), Positives = 106/184 (57%) Frame = +1 Query: 88 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267 +S KD +D+ + +D + S +R + ++ + K KII+KI+ +G+ N Sbjct: 532 ISAKDITDITNALNHDIDSVCVSNVRTAEDIRVVKRHC--QSKQTKIIAKIQTLEGVQNY 589 Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447 DEI+ SD +++ARG L + IP EK+ QK +I + N KPV+ + +L+SMV P Sbjct: 590 DEILKVSDAVLIARGYLTVHIPVEKLHFKQKELIQKSNESLKPVLVSCNILDSMVSSLLP 649 Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 627 T E+ +++N + D D ++LSGET+ G YP++ V T++ IC E EA RQ+ +L Sbjct: 650 TTCEVGEISNLVSDYVDAIILSGETSYGMYPIQAVETLSRICMETEA----RQILKNLND 705 Query: 628 EVKP 639 +P Sbjct: 706 TTRP 709 >UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform B - Apis mellifera Length = 538 Score = 121 bits (292), Expect = 2e-26 Identities = 66/230 (28%), Positives = 127/230 (55%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G++ K + L V LP +SEKD + + + D + + +RN L+ I+ E Sbjct: 199 GIVKDGKLIQLLDSLVPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLYTIKSRFKE 258 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 +++IISKI + QG+ NLDEI+ +D I++ R + +E+ +K+FL +K +IA+C ++ Sbjct: 259 M--SMRIISKISSQQGLENLDEILNAADAILLDRKGIEVEVGDKKLFLVEKIIIAKCIKM 316 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKP+I + ++ + K +++ +ANA+L+G D ++L + + + + + Sbjct: 317 GKPIILSFEVCDENDK----VNIDMNLIANAVLNGIDAILLKTGSLNVNDTSQLIKDIDI 372 Query: 568 ICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVV 717 +C+EAE W +++F++L ++ PIDP K A+AI++ Sbjct: 373 VCREAECARWQKEIFDELSYKIPIPIDPLHSIIIGGVNISLKSNAAAIII 422 >UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC 50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803 Length = 553 Score = 118 bits (284), Expect = 1e-25 Identities = 71/192 (36%), Positives = 107/192 (55%), Gaps = 6/192 (3%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G LG+RKG+ +P + L +S KD D+ G+D I SF++ A + E R + + Sbjct: 188 GKLGARKGITIPTRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKADVIEARDYIAK 247 Query: 208 -KGKNI-----KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMI 369 +N ++ SKIE ++++D+I SD +MVARGDL IE KV QK + Sbjct: 248 LHAENPASFCPRVCSKIEKPTAVLDIDDIALLSDMLMVARGDLAIETCLSKVCSIQKYIC 307 Query: 370 ARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVEC 549 R G + ATQM+ES+++ PTRAE++DVA+ DGA+ V+++ ETA G PV Sbjct: 308 ERARYHGCQAMVATQMVESLIENTVPTRAEVTDVASVCFDGANSVLVTAETAAGHDPVNV 367 Query: 550 VHTMANICKEAE 585 V + +I E Sbjct: 368 VKVLRSILTTTE 379 >UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquilingensis IC-167|Rep: Pyruvate kinase - Caldivirga maquilingensis IC-167 Length = 456 Score = 118 bits (284), Expect = 1e-25 Identities = 61/186 (32%), Positives = 101/186 (54%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G++ + K + + LP + ++DK + + ++ + S +R+ + R L Sbjct: 140 GIIRTHKSITIMNKDYPLPILGDRDKEAIKVAAKYNLEYLGLSHVRSVEDIESTREYLRS 199 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 + II K+E + ++ +I +D +MVARGDLG+ E+V Q+ +I + Sbjct: 200 LNYSPMIIVKVETASAIRSIKDIACNADYVMVARGDLGMVFNLEEVPKIQEKIITAAHSC 259 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 GKPV+ ATQ+LESMV P PTRAE+ D+ ++L G D ++L+ ET G+YPVE V + Sbjct: 260 GKPVMVATQLLESMVNNPVPTRAEVVDIMTSVLQGVDSLLLTDETTMGNYPVEAVEWLRR 319 Query: 568 ICKEAE 585 I E Sbjct: 320 IVSNYE 325 >UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Pyruvate kinase - Theileria parva Length = 699 Score = 116 bits (278), Expect = 8e-25 Identities = 61/123 (49%), Positives = 77/123 (62%), Gaps = 1/123 (0%) Frame = +1 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 E + II KIE + ++ EI+ SDG+MVARGDLGIE + + QK +I C Sbjct: 407 ENLSGVGIIPKIEKQAALDDIHEILKVSDGLMVARGDLGIETDLANLPIVQKRLIQLCRV 466 Query: 385 V-GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 561 V KP I ATQMLE+M P PTRAE+SDV+NA+ DGAD VMLS E+A G YP V+ Sbjct: 467 VYRKPCIVATQMLETMRSSPTPTRAEVSDVSNAVFDGADAVMLSAESATGHYPKASVNVQ 526 Query: 562 ANI 570 + Sbjct: 527 RRV 529 Score = 39.9 bits (89), Expect = 0.062 Identities = 19/58 (32%), Positives = 34/58 (58%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 L SRKG ++P + + + + EKD D +F + GVD + SF++N + + + IL + Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQNKSDILYLINILND 350 >UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_11, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 475 Score = 115 bits (276), Expect = 1e-24 Identities = 55/97 (56%), Positives = 70/97 (72%) Frame = +1 Query: 298 MVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVAN 477 MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+ P PTRAE+SD+A Sbjct: 243 MVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMINHPTPTRAEVSDIAI 302 Query: 478 AILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA 588 A+ +GAD VMLSGETA G YP++ V M + E+ Sbjct: 303 AVREGADAVMLSGETAHGKYPLKAVKVMHTVALRTES 339 Score = 40.7 bits (91), Expect = 0.036 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF-IRNGAALHE 186 + G L SR+ +N+ G LP++++KD D+ FGV+ VD SF +N +HE Sbjct: 112 DGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFWEKNYHMMHE 167 >UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Babesia bovis|Rep: Pyruvate kinase family protein - Babesia bovis Length = 693 Score = 115 bits (276), Expect = 1e-24 Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 1/123 (0%) Frame = +1 Query: 220 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKP 396 I II KIE + +++ I+ SDG+M+ARGDLG+E + + QK +I C V KP Sbjct: 403 IAIIPKIEKQPALDDINGILEVSDGMMIARGDLGVETEITNLPVIQKRLIQLCRLVYHKP 462 Query: 397 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 576 VI ATQMLESM P+P+RAE +D ANA+ DGAD VMLS E+A G YP V T + Sbjct: 463 VIVATQMLESMKSNPKPSRAEATDCANAVYDGADAVMLSAESATGAYPAHSVRTQRLLLY 522 Query: 577 EAE 585 AE Sbjct: 523 NAE 525 Score = 43.2 bits (97), Expect = 0.007 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G+L SRKG +P + + + SEKD D +F G+D + SF++ + ++ I+ Sbjct: 280 NDGVLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQRMTDILYLKNII 339 >UniRef50_Q8TGR8 Cluster: Uncharacterized protein YAL037C-B; n=1; Saccharomyces cerevisiae|Rep: Uncharacterized protein YAL037C-B - Saccharomyces cerevisiae (Baker's yeast) Length = 324 Score = 115 bits (276), Expect = 1e-24 Identities = 57/174 (32%), Positives = 101/174 (58%) Frame = -3 Query: 618 VIEELPVPDYSFSLLANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSGGTG 439 VI V D FS + H N +D +V LG +H+ VS+++D V + + SG + Sbjct: 139 VIVVWQVSDSLFSNDSGFSHSGNGVDWVVTLGGFTRQHNTVSTIQDSVTDIGNFSSGWSW 198 Query: 438 LLNHGFQHLSRTDHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTIGFSYNLV*ID 259 +++HGFQHL TD+W ++ + + LL + + D +TQ+++ NH+T+ + V + Sbjct: 199 VVSHGFQHLGSTDNWLTSQVRLSNQFLLDSQDFWGWDFNTQVTSGNHNTVSDLQDFVEVV 258 Query: 258 HSLVIFDLGDDLDVLAFFAEDAANLVQRGAVADE*RENHINALFDAEEQVRLVL 97 ++L++F+L +DLDVL F +D ++ +DE E+H++ + D E Q+ LVL Sbjct: 259 NTLLVFNLDNDLDVLTLFTQDFSDGQNIVGGSDERSEDHVDTVLDTESQIFLVL 312 >UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus tenax|Rep: Pyruvate kinase - Thermoproteus tenax Length = 446 Score = 111 bits (268), Expect = 1e-23 Identities = 62/190 (32%), Positives = 103/190 (54%), Gaps = 2/190 (1%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDL--LFGVEQGVDMIFASFIRNGAALHEIRG 195 ++G++ S K + + G + E+D L L VD + S +R+GA + ++R Sbjct: 140 SSGVISSNKAIVVKGKEYHIEQPVEEDIRALQTLSRFRDDVDYVALSLVRDGADVRKMRS 199 Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 ++ E G I++KIE + ++EII +D I++ARGDL + E + Q+ ++ R Sbjct: 200 VVEEAGLTSGIMAKIETKSAVDKIEEIINAADYIVIARGDLALHYGLEYIPKVQRLLVER 259 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 G+PV ATQ+L+SM PTRAE++DV G D + L+ ETA G++P+E V Sbjct: 260 SLSAGRPVAVATQLLDSMQTNTTPTRAEVNDVYTTASLGVDSLWLTNETASGEHPLEAVD 319 Query: 556 TMANICKEAE 585 + I + E Sbjct: 320 WLRRIVSQVE 329 >UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: Pyruvate kinase - Pyrobaculum aerophilum Length = 461 Score = 109 bits (263), Expect = 5e-23 Identities = 59/191 (30%), Positives = 103/191 (53%), Gaps = 2/191 (1%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDL--LFGVEQGVDMIFASFIRNGAALHEIR 192 +++G++ K + + G D+ +E+D L + + +D + S ++ + +R Sbjct: 156 ESSGVITGGKAIVVEGKDYDISTPAEEDVEALKAISPIRDNIDYVAISLAKSCKDVDSVR 215 Query: 193 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIA 372 +L E G ++ KIE + NL+E++ SD ++VARGDLG+ + + + Q+ ++ Sbjct: 216 SLLTELGFQSQVAVKIETKGAVNNLEELVQCSDYVVVARGDLGLHYGLDALPIVQRRIVH 275 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 + GKP+ ATQ+L+SM P PTRAEI+DV G D + L+ ETA G YP+ V Sbjct: 276 TSLKYGKPIAVATQLLDSMQSSPIPTRAEINDVFTTASMGVDSLWLTNETASGKYPLAAV 335 Query: 553 HTMANICKEAE 585 ++ I E Sbjct: 336 SWLSRILMNVE 346 >UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella aurantiaca DW4/3-1 Length = 515 Score = 108 bits (260), Expect = 1e-22 Identities = 46/103 (44%), Positives = 72/103 (69%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G L + KG+NLPG+ V A++ KD+ DL+FG+++GVD + SF+R A + R + E Sbjct: 159 GTLKNNKGINLPGVAVRADALTPKDREDLVFGIKEGVDFLALSFVRQPADIELARQAMAE 218 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPP 336 G+ + I++K+E + + LD I+ ++DG+MVARGDLG+EIPP Sbjct: 219 AGRQVPIVAKLEKPEAIARLDAILDKTDGVMVARGDLGVEIPP 261 Score = 38.3 bits (85), Expect = 0.19 Identities = 29/88 (32%), Positives = 34/88 (38%) Frame = +3 Query: 318 GYRDPSRKGIPRPEDHDRQMQSGWKTSDLCDSNAGIHG*EAPSHQSRDL*RSQRHPRRS* 497 G P R G RPE H +Q ++A + E P H R QR RR Sbjct: 256 GVEIPPRGGAGRPEGHHPALQPARPAGHRGHADAQLDDREPPPHARGGQRRGQRRVRRGG 315 Query: 498 LRDALRGDCQGRLSCRVCSHHGQHLQGG 581 AL D Q L RV + G H GG Sbjct: 316 RGHALGRDGQRPLPHRVGADDGPHRPGG 343 >UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Pyruvate kinase - Paramecium tetraurelia Length = 700 Score = 107 bits (257), Expect = 3e-22 Identities = 57/166 (34%), Positives = 91/166 (54%) Frame = +1 Query: 88 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267 ++ KD +D D I S + +HE++ +LG NI+I +I +G+ N Sbjct: 292 ITSKDINDFTIAKRLDFDSITLSNVSRPEEVHELKHLLGSS-TNIQIFVRITTQEGINNF 350 Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447 D+I+ +DG ++AR L E V Q MI C ++ KPV+ +TQ+LESM+ + P Sbjct: 351 DKIMEIADGCIIARAYLATWAQIEDVVQMQHDMILNCRKLVKPVLISTQILESMLTQTNP 410 Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585 T AE+ D+A+ + D +MLSGET G++P++ V +A I E Sbjct: 411 TFAEMGDIADVVEQHIDGIMLSGETTYGNHPIKVVQALARISTNIE 456 >UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jejuni|Rep: Pyruvate kinase - Campylobacter jejuni Length = 319 Score = 107 bits (256), Expect = 4e-22 Identities = 66/177 (37%), Positives = 99/177 (55%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 + G+L + KG+++ + ++P + EKDK + E + + ASF+R + + EI+ +L Sbjct: 129 STGLLLNNKGMHVRNLHDNIPFLFEKDKELIKLCNEFDIAYVGASFVRKASDIQEIKQVL 188 Query: 202 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 N KIISKIE + + NL I+ E + I++ RGDL EI EK+ Q ++ + Sbjct: 189 HS---NTKIISKIETLEAVNNLYSILQEVEYILIDRGDLSTEIGIEKIPRFQNYIVEMAH 245 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 V ATQ+L++M +KP PT AEI D+ N G V LS ETA G Y ECV Sbjct: 246 HNAIKVFLATQILKNMEEKPIPTIAEIDDLYNIAKSGVFGVQLSEETAVGHYVEECV 302 >UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate kinase, liver and RBC, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to pyruvate kinase, liver and RBC, partial - Ornithorhynchus anatinus Length = 339 Score = 106 bits (254), Expect = 6e-22 Identities = 46/80 (57%), Positives = 64/80 (80%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 ++ G LGSRKGVN+PG +DLPAVSE+D DL FG++Q VD++FASF+R A + E+R Sbjct: 60 ESGGRLGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAADVAEVRAA 119 Query: 199 LGEKGKNIKIISKIENHQGM 258 LG +G+ +K+ISKIENH+G+ Sbjct: 120 LGPRGRAVKVISKIENHEGV 139 >UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG7070-PB, isoform B - Tribolium castaneum Length = 535 Score = 104 bits (250), Expect = 2e-21 Identities = 67/234 (28%), Positives = 123/234 (52%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 + AG+L V LP +P+ LP +K + + +D++F + L ++ Sbjct: 213 EKAGLLTDNLSVKLPNVPITLPKTESHEKL-IQIKEKCEIDIVFVG----PSKLDMVKET 267 Query: 199 LGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARC 378 LG + II+K+E + D ++ +SDG+++ G+ + E+VFL QK++IA C Sbjct: 268 LGP---TVLIIAKLEYASSVDFFDSLVKKSDGVIID-GEKLMATSKERVFLVQKSVIANC 323 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 N++GKPV+ A + T++ ++D+AN ++DG D ++L + + + + Sbjct: 324 NKLGKPVLAA-------INCHAVTKSIVNDIANTVIDGIDGLLLPPDP-------DLIES 369 Query: 559 MANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVI 720 ++ ICK AE ++ ++LF+DLVS PPI+P K A+AI++I Sbjct: 370 ISLICKAAEGAVYQKRLFDDLVSLKPPPIEPIISIAISAVEASFKSNAAAIILI 423 >UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 710 Score = 103 bits (248), Expect = 3e-21 Identities = 75/186 (40%), Positives = 102/186 (54%), Gaps = 7/186 (3%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 210 LGS K +N+P + ++ KD DL + V DM+ SFIR+ + +R L + K Sbjct: 516 LGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGISFIRDVHDITVLRQELKKRK 574 Query: 211 GKNIKIISKIENHQGMVNLDEIIAESD------GIMVARGDLGIEIPPEKVFLAQKTMIA 372 ++ I+ KIE G NL I+ E+ GIM+ARGDL +E E++ Q+ +IA Sbjct: 575 LDDLGIVLKIETKSGFKNLSLILLEAMKCSNPLGIMIARGDLAVECGWERLANMQEEIIA 634 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 C PVI ATQ+LES+VK PTRAEI+D ANA A CVML+ KG VE V Sbjct: 635 ICKAARVPVIMATQVLESLVKSGVPTRAEITDAANA--KRASCVMLN----KGKNIVEAV 688 Query: 553 HTMANI 570 + I Sbjct: 689 SMLDTI 694 >UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus Length = 501 Score = 103 bits (246), Expect = 6e-21 Identities = 69/196 (35%), Positives = 107/196 (54%), Gaps = 7/196 (3%) Frame = +1 Query: 19 DNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGI 198 D L + KG+N P + L +SE+D L F V + D++ SF + ++ Sbjct: 295 DKGSRLAADKGINFPESRLKLRGLSEQDLEHLDF-VARRADIVGMSFANEPEDVFALQAA 353 Query: 199 LGEKGK-NIKIISKIENHQGMVNLDEIIAES-----DGIMVARGDLGIEIPPEKVFLAQK 360 LGE+G ++ I+ KIE +G L +I + G+M+ARGDL +E E+ Q+ Sbjct: 354 LGERGAGHLGILLKIETRRGFEQLPRLILAAMRSYPAGVMIARGDLAVECGWERTAEVQE 413 Query: 361 TMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540 ++ C PV+ ATQ+LE + KK P+RAEI+D A+ A+CVML+ KG + Sbjct: 414 EILWLCEAGHMPVVWATQVLEKLAKKGLPSRAEITDA--AMSQRAECVMLN----KGPHI 467 Query: 541 VECVHTMANI-CKEAE 585 VE VH++A+I C+ E Sbjct: 468 VEAVHSLADILCRMQE 483 >UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfringens|Rep: Pyruvate kinase - Clostridium perfringens Length = 364 Score = 101 bits (242), Expect = 2e-20 Identities = 66/194 (34%), Positives = 104/194 (53%), Gaps = 5/194 (2%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G++ KG NLP + VSEKD D+ F ++ VD+I S+ E + I+ + Sbjct: 161 GVVRKEKGCNLPNLDRKNWGVSEKDLEDIKFAIDNKVDIIDYSYCSYMEECREFKNIVFK 220 Query: 208 KGKNIKII----SKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 K+ + I KIE ++G+ N+ E+ E DGI++ARGDL EI V + Q+ ++ Sbjct: 221 NLKSNQFIPKLWGKIETNEGINNIKEVAKELDGIVIARGDLTAEIGILNVPIVQEKILYA 280 Query: 376 CNRVGKPVICATQMLESM-VKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 K +I AT +L S+ K+ +PT E+SD+ + I GA ML+GET+ G+ V Sbjct: 281 LKNENKSIIVATNVLSSIRNKQNKPTINELSDIYHFIRCGATGFMLTGETSTGENEEYVV 340 Query: 553 HTMANICKEAEAVI 594 T+ N K E ++ Sbjct: 341 TTLKNSIKYYEKLL 354 >UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_171, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 622 Score = 99.1 bits (236), Expect = 1e-19 Identities = 70/184 (38%), Positives = 104/184 (56%), Gaps = 8/184 (4%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 213 LG+ K +N+P + ++ KD DL F V DM+ SFIR+ + +R L EK Sbjct: 422 LGAEKSINIPESNIRFEGLTTKDLMDLEF-VAAHADMVGISFIRDVRDIVVLRAEL-EKR 479 Query: 214 K--NIKIISKIENHQGMVNLDEIIAESD------GIMVARGDLGIEIPPEKVFLAQKTMI 369 K N+ I+ KIE G L ++ E+ G+M+ARGDL +E E++ Q+ ++ Sbjct: 480 KLHNLGIVLKIETSSGFDKLPLLLLEAMKSPNPLGVMIARGDLAVECGWERLGDIQEEIL 539 Query: 370 ARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVEC 549 + C+ PVI ATQ+LES+VK PTRAE++DVAN A C+ML+ KG + V+ Sbjct: 540 SICSAAHVPVIWATQVLESLVKSGVPTRAELTDVANG--RRASCIMLN----KGKHIVDA 593 Query: 550 VHTM 561 V T+ Sbjct: 594 VSTL 597 >UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetraurelia|Rep: Pyruvate kinase - Paramecium tetraurelia Length = 509 Score = 96.7 bits (230), Expect = 5e-19 Identities = 50/166 (30%), Positives = 94/166 (56%) Frame = +1 Query: 88 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 267 ++E+D D+ + E D I S + + +++ L +K ++++ ++I L Sbjct: 200 MTEQDILDIDYACECNFDSITFSKVNTALDIIKVKERLEQKYPHVQVFARIAEKLKEEQL 259 Query: 268 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 447 +EII +DG ++AR + + P E V Q +I+ C ++ KPV +T +LESM + +P Sbjct: 260 EEIITLADGCIIARSHISMTQPVEDVVKYQTQIISSCRKLFKPVFVSTYILESMSVQLKP 319 Query: 448 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585 + A++ D++N + D ++LSGE + G +PV V T+ NIC++ E Sbjct: 320 SFADMGDISNIVKQYIDGILLSGEASFGKFPVLIVQTLNNICRKIE 365 >UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep: Pyruvate kinase - Mycobacterium sp. (strain JLS) Length = 615 Score = 95.1 bits (226), Expect = 2e-18 Identities = 62/187 (33%), Positives = 106/187 (56%), Gaps = 6/187 (3%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 213 LGS KGVN+P + + A+++KD DL V D++ SF++ + + ++ L G Sbjct: 411 LGSAKGVNVPDTHLPIAALTDKDVEDLATVVAIA-DIVQISFVQRPSDITQLHDELHRLG 469 Query: 214 -KNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIAR 375 ++ ++ KIE + +L +++ + G+M+ARGDL +E+ E++ Q+ ++ Sbjct: 470 GDHLGVVLKIETRRAFEHLPQLLLTAMRRPRVGVMIARGDLAVEVGYERLAEVQEEVLWL 529 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 C PVI ATQ+LES+ K P+RAEISD A + A+CVML+ KG + V+ V Sbjct: 530 CEAAHLPVIWATQVLESLAKSGLPSRAEISDAAMG--ERAECVMLN----KGPHIVDAVV 583 Query: 556 TMANICK 576 + +I + Sbjct: 584 VLDDILR 590 >UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp. BL107|Rep: Pyruvate kinase - Synechococcus sp. BL107 Length = 359 Score = 94.7 bits (225), Expect = 2e-18 Identities = 65/206 (31%), Positives = 106/206 (51%), Gaps = 3/206 (1%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G + ++ P+ L +E D + + IF SF + + R + Sbjct: 150 GTCEKNRAFDIANKPLILKPHTEFDIWAIKESTKHSCPAIFHSFAESAEDIKTTRSLC-- 207 Query: 208 KGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 387 KG++ K+I+KIE+ +G+ ++ EI SDGI++ RGDL EI V +A C + Sbjct: 208 KGQS-KVIAKIESRRGLESIKEIATASDGILIDRGDLSREISISMVPVAVNLATKLCVEI 266 Query: 388 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 567 KP+ AT +L+S++ P+RAEISD+ N + G ++L+ E A G P+E V + + Sbjct: 267 EKPIYVATNVLDSLMSNSLPSRAEISDIHNMLTMGVTGMVLAAEVAIGARPIESVQVVNH 326 Query: 568 ICKEAEA-VIWHRQLF--NDLVSEVK 636 I K EA + +F NDL +E+K Sbjct: 327 IRKIVEAQKLGILGIFNSNDLKTELK 352 >UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 626 Score = 93.5 bits (222), Expect = 5e-18 Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 6/190 (3%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 210 L + KG+NLP +++ +++ D S L F + + D + SF+ + + + L K Sbjct: 424 LRAGKGMNLPDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNSAHDVTLLDEALSRVK 482 Query: 211 GKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIAR 375 G ++ I+ KIE +G NL ++ + G+M+ARGDL +E E++ Q+ +++ Sbjct: 483 GDHLGIVLKIETRRGFENLPSMLLTAMRRPKVGVMIARGDLAVECGYERLAEVQEEILSV 542 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 C PVI ATQ+LE++ +K P+RAEISD A A+CVML+ KG + +E + Sbjct: 543 CEAAHVPVIWATQVLENLAQKGMPSRAEISDAVMA--HRAECVMLN----KGPHVIEALG 596 Query: 556 TMANICKEAE 585 + +I K E Sbjct: 597 VLDSILKRME 606 >UniRef50_O58306 Cluster: Putative uncharacterized protein PH0571; n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized protein PH0571 - Pyrococcus horikoshii Length = 181 Score = 93.1 bits (221), Expect = 6e-18 Identities = 57/118 (48%), Positives = 73/118 (61%) Frame = -1 Query: 587 ASASLQMLAMV*THSTG*SPLAVSPESITQSAPSRMALATSEISALVGRGFLTMDSSI*V 408 +S + +LA++ T S G P AVS ++IT S PS +ALATS SALVG + M++SI V Sbjct: 43 SSVTFAILAIISTASIGNFPTAVSSDNITASVPSSIALATSVTSALVGTFSIVMETSIWV 102 Query: 407 AQITGFPTRLHLAIMVFWARNTFSGGISIPRSPRATMIPSDSAIISSKLTIPW*FSIL 234 A ITGFP+ L I +FW + S GIS PRSP A +IPS + IS K SIL Sbjct: 103 AVITGFPSMLAFLINLFWRIGSCSIGISTPRSPLAIIIPSAAFRISLKFLTASGLSIL 160 >UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: Pyruvate kinase - Geobacillus kaustophilus Length = 660 Score = 92.3 bits (219), Expect = 1e-17 Identities = 62/187 (33%), Positives = 107/187 (57%), Gaps = 8/187 (4%) Frame = +1 Query: 49 GVNLPG--IPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-N 219 G++LP + + +P ++++D + F + + D++ SF++ L ++ +L E+G + Sbjct: 455 GIHLPDSFLHLTVPPLTDRDLEWIPF-IARWADIVGLSFVQAPHDLRKLYHLLAEQGAGS 513 Query: 220 IKIISKIENHQGMVNLDEIIAE-----SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384 + +I+KIE + N I+ E + G+M+ARGDL +EI E + AQ ++A C Sbjct: 514 LPVIAKIETRAALHNFVRILLEGLKFPAFGVMIARGDLALEIGFEHLAAAQNDVLALCRA 573 Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 564 PVI ATQ+LE M KK P+RAEISDV + A C+ML+ KG + E V ++ Sbjct: 574 AHIPVIWATQVLEQMAKKGIPSRAEISDV--FVGKQAQCIMLN----KGRHIAEAVRLLS 627 Query: 565 NICKEAE 585 ++ ++ E Sbjct: 628 SLLEKEE 634 >UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacteria|Rep: Pyruvate kinase - Stappia aggregata IAM 12614 Length = 512 Score = 92.3 bits (219), Expect = 1e-17 Identities = 63/181 (34%), Positives = 98/181 (54%), Gaps = 8/181 (4%) Frame = +1 Query: 16 QDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA---ALHE 186 +D+ + +KG+NLP + + ++ KDK+DL V DM+ SF+ L E Sbjct: 306 KDSGVKIKPQKGINLPDTALGVSPLTAKDKTDLKT-VTALADMVGYSFVSEPDDIDLLEE 364 Query: 187 IRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFL 351 +G + I++KIE + + NL +IA + G IM+ARGDL EI E++ Sbjct: 365 ALASIGAANHPLGIVAKIERPEAVQNLPALIARASGTRPLAIMIARGDLASEIGFERLAE 424 Query: 352 AQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKG 531 Q+ ++ C PVI ATQ+LES+VK P+R +++D A A A+CVML+ A G Sbjct: 425 MQEEILWICEAASTPVIWATQVLESLVKFGSPSRGDMTDAAMAA--RAECVMLNKGPAVG 482 Query: 532 D 534 + Sbjct: 483 E 483 >UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri (strain A1501) Length = 625 Score = 91.5 bits (217), Expect = 2e-17 Identities = 65/207 (31%), Positives = 106/207 (51%), Gaps = 6/207 (2%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-K 210 L S KG+N P + + A +E D L F + D++ SF + + E+ L Sbjct: 417 LASDKGINFPDNALPVRAPTEDDIETLAFAAKHA-DIVQMSFANSAEDVIELIDHLERLD 475 Query: 211 GKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIAR 375 ++ ++ KIE G NL +++ G+M+ARGDL +E E++ Q+ M+ Sbjct: 476 ATHLGVVLKIETRAGFENLPKMLLAGMRLPRFGVMIARGDLAVETGFERLAEIQEEMLCL 535 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 C PVI ATQ+LES+ KK P R+EI+D A ++ A+CVML+ KG Y ++ V Sbjct: 536 CEAAHVPVIWATQVLESLAKKGAPARSEITDAAMSV--RAECVMLN----KGPYILKAVT 589 Query: 556 TMANICKEAEAVIWHRQLFNDLVSEVK 636 T+ ++ + HR DL+ ++ Sbjct: 590 TLNDVLRRMRE---HRAKKRDLLRSLQ 613 >UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Pyruvate kinase - Flavobacteriales bacterium HTCC2170 Length = 624 Score = 91.1 bits (216), Expect = 3e-17 Identities = 62/195 (31%), Positives = 99/195 (50%), Gaps = 5/195 (2%) Frame = +1 Query: 16 QDNAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRG 195 +D L + KG+NLP + + ++ KD+ D+ F + + D + SF+ + + ++ Sbjct: 409 KDKGSKLKADKGINLPKSDLKISGLTNKDREDIKF-IAKHADAVNFSFVNSKEDILDLYN 467 Query: 196 ILGEKGKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQK 360 L + I +I KIE +G NL I+ + G+M ARGDL IE + Q+ Sbjct: 468 ELDKLDSKIGVILKIETEKGFSNLPSILLTAMRSFPIGVMTARGDLAIETGWKNFASIQQ 527 Query: 361 TMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540 ++ C P I ATQ+LE++ KK P+RAEI+D A+ A+CVML+ KG Y Sbjct: 528 EIMRICAAAHIPNIWATQVLENLAKKGTPSRAEITDA--ALAQQAECVMLN----KGYYI 581 Query: 541 VECVHTMANICKEAE 585 V + I + E Sbjct: 582 QRAVKMLDKILRRME 596 >UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Pyruvate kinase - Clostridium beijerinckii NCIMB 8052 Length = 340 Score = 89.8 bits (213), Expect = 6e-17 Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 4/185 (2%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 207 G++ KG N+ + ++E DK +++GV VD+I SF+ + +++ L Sbjct: 149 GVIRKWKGCNIKNLERKELPLNENDKDAIVWGVNNKVDIICQSFVEEKKDIDDVKLFLNN 208 Query: 208 KGKNI---KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR- 375 + N KI +KIE G+ N+ I++E+DGI++ RGDL E E + ++ +I Sbjct: 209 RKSNQFKPKIWAKIETLNGVNNIKSILSEADGIVIGRGDLIPETSIEDTPIYEERIIKEV 268 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 555 K +I AT +L SM P+ +E+ + N I GA +L+GET+ G P+ V Sbjct: 269 LGDKDKEIIIATHILNSMKNGKMPSISEVESIYNFIKIGATGFLLAGETSIGKAPIRTVE 328 Query: 556 TMANI 570 + N+ Sbjct: 329 FLNNL 333 >UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphaeroides|Rep: Pyruvate kinase - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 508 Score = 87.0 bits (206), Expect = 4e-16 Identities = 56/165 (33%), Positives = 96/165 (58%), Gaps = 9/165 (5%) Frame = +1 Query: 46 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 225 +GVNLPG +D+ A++E+D + L V + D++ SF++ + + + + + + Sbjct: 309 RGVNLPGSHLDVAALTEEDLAALDVVVAEA-DLVAFSFVQTPGDVRALIAAMEARACHPR 367 Query: 226 ----IISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARC 378 I+ KIE G+ L E+I E+ G +M+ARGDL +EI +++ Q+ ++ C Sbjct: 368 PLPAILLKIETPMGLHLLPELIVEAGGSLPVGVMIARGDLAVEIGFDRLSEIQEEILWLC 427 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLS 513 PV+ ATQ+LE MVK+ + +RAE++D A+ ADCVML+ Sbjct: 428 EAAKVPVVWATQVLEGMVKEGQASRAEVTDA--AMSQRADCVMLN 470 >UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep: Pyruvate kinase - Corynebacterium efficiens Length = 630 Score = 86.6 bits (205), Expect = 5e-16 Identities = 65/199 (32%), Positives = 107/199 (53%), Gaps = 14/199 (7%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA-------ALHEIR 192 L + KG+NLP + LP+++E+D L F V + D++ SFIR+ AL +I Sbjct: 417 LAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKHADIVNVSFIRDTGDVEYVLDALAQIA 475 Query: 193 GILGEKGK--NIKIISKIENHQGMVNLDEIIA-----ESDGIMVARGDLGIEIPPEKVFL 351 GE K + ++ KIE G NL +I+ E+ G+M+ARGDL +E+ +++ Sbjct: 476 EETGEHDKIRELGLVLKIETIPGYENLAQIMLTGMRHENFGVMIARGDLAVELGFDRMAE 535 Query: 352 AQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKG 531 + ++A P I ATQ+LE+M K P+RAEI+D A+ +CVML+ KG Sbjct: 536 VPQLIMALAEAAHIPTIFATQVLENMAKNGLPSRAEITDATLAL--RCECVMLN----KG 589 Query: 532 DYPVECVHTMANICKEAEA 588 + + + ++ + K+ A Sbjct: 590 PHINDAIKVLSRMSKKLGA 608 >UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep: Pyruvate kinase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 506 Score = 85.8 bits (203), Expect = 1e-15 Identities = 61/190 (32%), Positives = 102/190 (53%), Gaps = 9/190 (4%) Frame = +1 Query: 46 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAAL----HEIRGILGEKG 213 KG+N P + L ++ D+ L F D+I S++++ + E+ G+ Sbjct: 296 KGLNFPDSDLRLCPLTASDREHLAFACRYA-DIIGYSYVQSAEDIALLQRELAHCCGDCA 354 Query: 214 KNIKIISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARC 378 + II+KIE + + L E+I ++ G +M+ARGDL +EI +++ Q+ ++ C Sbjct: 355 DQMGIIAKIETPKAIRALPEMIIQAAGRQPFGVMIARGDLAVEIGYQRLAEMQEEILWLC 414 Query: 379 NRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHT 558 PV+ ATQ+LE++VKK P+RAEI+D A A + A+CVML+ KG Y V Sbjct: 415 EAAHVPVVWATQVLENLVKKGVPSRAEITDAAMA--ERAECVMLN----KGPYVGLAVDI 468 Query: 559 MANICKEAEA 588 + ++ EA Sbjct: 469 LDDVLARMEA 478 >UniRef50_Q19Q27 Cluster: Acyl-CoA desaturase-like; n=2; Belgica antarctica|Rep: Acyl-CoA desaturase-like - Belgica antarctica Length = 316 Score = 81.0 bits (191), Expect = 3e-14 Identities = 44/69 (63%), Positives = 52/69 (75%) Frame = -1 Query: 647 SIGGFTSDTRSLKSCLCQITASASLQMLAMV*THSTG*SPLAVSPESITQSAPSRMALAT 468 S+G DT+S LCQ+ ASAS+ +LAMV HS+G SPLAVSP++I QSAPSR ALAT Sbjct: 248 SMGVGWRDTKSRNRFLCQMAASASIWVLAMVVIHSSGYSPLAVSPDNIVQSAPSRTALAT 307 Query: 467 SEISALVGR 441 SEISA V R Sbjct: 308 SEISARVAR 316 >UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestinalis|Rep: Pyruvate kinase - Giardia lamblia (Giardia intestinalis) Length = 517 Score = 80.6 bits (190), Expect = 4e-14 Identities = 45/120 (37%), Positives = 66/120 (55%) Frame = +1 Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405 +++K+E ++NL +I+ DGIM+ARG LG E+ + QK++I GK Sbjct: 264 LMTKVETPLAVLNLKQIVTHVDGIMIARGALGDEMDFSYLPSIQKSIIQIARDSGKMCYI 323 Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585 AT + ESM + PTRAE+SDV N + DG D +L ET+ G + V V + I E Sbjct: 324 ATNVCESMSENVIPTRAEVSDVTNCLGDGCDGFVLCAETSTGHHSVATVKYLVEIIVAVE 383 >UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 476 Score = 79.8 bits (188), Expect = 6e-14 Identities = 57/180 (31%), Positives = 97/180 (53%), Gaps = 7/180 (3%) Frame = +1 Query: 34 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG 213 L + KG+N P + + ++++KD DL F V D++ SF++ A L + L + Sbjct: 276 LRAEKGLNFPDSQLQIRSLTDKDCQDLDFVVRHA-DLVGYSFVQQPADLQLLVSELERRQ 334 Query: 214 K--NIKIISKIENHQGMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIA 372 ++ +I K+E + + NL +IA G +M+ARGDL +EI ++ Q+ ++ Sbjct: 335 ARPDLGLILKMETQRAVKNLPALIATVAGCRPLGVMIARGDLAVEIGWLRLGEIQEELLW 394 Query: 373 RCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 552 C PV+ ATQ+L+ + K+ P+R E+SD + A+CVML+ KG Y +E V Sbjct: 395 ICEAAQVPVVWATQVLDQLTKEGLPSRPELSDAVMSA--RAECVMLN----KGPYLLEAV 448 >UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba histolytica HM-1:IMSS|Rep: pyruvate kinase - Entamoeba histolytica HM-1:IMSS Length = 321 Score = 64.9 bits (151), Expect = 2e-09 Identities = 50/173 (28%), Positives = 89/173 (51%), Gaps = 2/173 (1%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFA-SFIRNGAALHEIRGILG 204 G L KG NL P +SE+D ++++ ++ ++ FA SF+ + EI+ + Sbjct: 139 GELKPGKGFNLQPHPFVQNQLSERD-AEIVEKLKDVKEVCFALSFV---CVVEEIQDL-- 192 Query: 205 EKGKNIK-IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 381 +K N K I++KIE + L I ++ + I + RGD+G+++ + + Sbjct: 193 KKRSNGKYIVAKIEREMDLERLKAISSQCNEIWICRGDMGVQLGFVGMAKFVREYTTFMK 252 Query: 382 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYP 540 ++ P I A +++E + PTR+EI + N I DG + ++LS ET G YP Sbjct: 253 QLNCPSIMAGEVMEHLCDNTIPTRSEICYLGNLIADGYNGIVLSDETVFGKYP 305 >UniRef50_A7CFG4 Cluster: Putative uncharacterized protein; n=1; Ralstonia pickettii 12D|Rep: Putative uncharacterized protein - Ralstonia pickettii 12D Length = 1350 Score = 58.0 bits (134), Expect = 2e-07 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 7/137 (5%) Frame = -3 Query: 618 VIEELPVPDYSFSLL---ANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSG 448 ++EE+ + + LL A+ HG + LD + A G +HH + +VE GVG VR LG+ Sbjct: 510 LVEEVCIQMHGLRLLGFDADGSHGFDGLDGVAAGGGFRRQHHGIGTVEHGVGDVRHLGAR 569 Query: 447 GTGLLNHGFQHLSRTDHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTIGFSYNLV 268 + +H F HL D DH LL + Q++ +HD +G +L Sbjct: 570 RHRVDDHRFHHLRGGDGQLIVFAGQLDHALLQRRHGRVAHFHGQVATRDHDAVGGGQDL- 628 Query: 267 *IDHS----LVIFDLGD 229 +H+ L DLGD Sbjct: 629 -FEHARTDGLGTLDLGD 644 >UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 105 Score = 55.2 bits (127), Expect = 2e-06 Identities = 29/67 (43%), Positives = 43/67 (64%) Frame = -1 Query: 221 MFLPFSPRMPRISCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFR 42 M LP SP+ IS ++ + + +AKI+ T TP S +SFS+ AG+ST +PG+LTP Sbjct: 1 MSLPSSPKTFLISKTSLAVSIKEAKIMWTLFLTPNLISAISFSDKAGKSTSVPGKLTPLW 60 Query: 41 DPSIPAL 21 + +PAL Sbjct: 61 EEILPAL 67 >UniRef50_Q3JI08 Cluster: Putative uncharacterized protein; n=3; Burkholderia|Rep: Putative uncharacterized protein - Burkholderia pseudomallei (strain 1710b) Length = 989 Score = 44.8 bits (101), Expect = 0.002 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 1/115 (0%) Frame = +3 Query: 225 DHLQDRKSPGNGQFRRDYS*IRWYHGCSRRSGYRDPSRKGIPRPE-DHDRQMQSGWKTSD 401 D +DR++ G Q RRD R G +RRSG RD +R R E DH + + G +T D Sbjct: 251 DRREDREAAGGRQHRRDRRRGRCGDGRARRSGRRDVARGRAERAEADHPARARGG-QTGD 309 Query: 402 LCDSNAGIHG*EAPSHQSRDL*RSQRHPRRS*LRDALRGDCQGRLSCRVCSHHGQ 566 D++A I A + + R + RR DA+ G G +S R H Q Sbjct: 310 RRDADARIDDARADADARGGVRRRRGRLRRRRRGDAVGGIGVGPVSGRGGRFHAQ 364 >UniRef50_Q676G7 Cluster: Pyruvate kinase; n=1; Agrobacterium tumefaciens|Rep: Pyruvate kinase - Agrobacterium tumefaciens Length = 334 Score = 44.8 bits (101), Expect = 0.002 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 1/132 (0%) Frame = +1 Query: 145 IFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGI 324 I SF + + +++ I + +I II+KIE+ + NL I SDG+++ARGDLG Sbjct: 184 INVSFADSAIIIRQVKSIC--RFDHINIIAKIESKIAVDNLIGINEASDGLILARGDLGN 241 Query: 325 EIPPEKVF-LAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADC 501 + V +A K + R + G P+I AT K + +E + + A G + Sbjct: 242 FYDEQSVINIAHKIVELRPFQAG-PIIFATNYFTEPAKGLALSTSEQATIQEAFKLGVNT 300 Query: 502 VMLSGETAKGDY 537 ++++ ET+ + Sbjct: 301 ILVN-ETSSSQH 311 >UniRef50_A5P062 Cluster: Putative uncharacterized protein; n=2; Proteobacteria|Rep: Putative uncharacterized protein - Methylobacterium sp. 4-46 Length = 829 Score = 44.8 bits (101), Expect = 0.002 Identities = 37/116 (31%), Positives = 47/116 (40%) Frame = +3 Query: 234 QDRKSPGNGQFRRDYS*IRWYHGCSRRSGYRDPSRKGIPRPEDHDRQMQSGWKTSDLCDS 413 QDR++PG RRD+ + G RR RD G R E H + + D Sbjct: 246 QDREAPGARPSRRDHGGVGRADGRPRRPRRRDAPGTGAGRAEAHHPRGAPPRQARRGRDP 305 Query: 414 NAGIHG*EAPSHQSRDL*RSQRHPRRS*LRDALRGDCQGRLSCRVCSHHGQHLQGG 581 +A I R L R R R RDALR + G+ RV HH H + G Sbjct: 306 DARIDDQRPGPDPRRGLGRRHRGLRGGRCRDALRRERLGQFPGRVRRHHEPHRRAG 361 >UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep: Pyruvate kinase - Thermococcus litoralis Length = 220 Score = 44.0 bits (99), Expect = 0.004 Identities = 20/67 (29%), Positives = 39/67 (58%) Frame = +1 Query: 22 NAGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 201 N G+L S KG+N+P + + A++ +D + F +E GVD I SF+ + + +++ L Sbjct: 154 NGGILFSHKGINIPKANLPIEAITPRDFEIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFL 213 Query: 202 GEKGKNI 222 +K ++ Sbjct: 214 EKKSADL 220 >UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase - Endoriftia persephone 'Hot96_1+Hot96_2' Length = 246 Score = 43.2 bits (97), Expect = 0.007 Identities = 19/46 (41%), Positives = 27/46 (58%) Frame = +1 Query: 28 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 165 G L + KG+N G + PA++EKDK D+ F E D + SF+R Sbjct: 184 GKLSNNKGINKQGGGLSAPALTEKDKQDIKFAAEIDADYLAVSFVR 229 >UniRef50_A5BYI4 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep: Pyruvate kinase - Vitis vinifera (Grape) Length = 314 Score = 42.7 bits (96), Expect = 0.009 Identities = 18/37 (48%), Positives = 26/37 (70%) Frame = +1 Query: 391 KPVICATQMLESMVKKPRPTRAEISDVANAILDGADC 501 + I ATQML S++K P R + +D+ANA+L G+DC Sbjct: 207 RKAITATQMLGSIIKSLCPVRVKATDIANAVLGGSDC 243 >UniRef50_Q4JN61 Cluster: CG7362-PA; n=1; uncultured bacterium BAC13K9BAC|Rep: CG7362-PA - uncultured bacterium BAC13K9BAC Length = 254 Score = 39.1 bits (87), Expect = 0.11 Identities = 43/165 (26%), Positives = 75/165 (45%) Frame = +1 Query: 91 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 270 S+ DK + FG E + I + I NG L + I + GKNIK +++ LD Sbjct: 83 SDIDKY-IAFGKEISPE-IMSFDISNG--LDFFKTIKSKLGKNIKTCVRVKLGTSTEGLD 138 Query: 271 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 450 + E D M IE+ KV K ++ + + +P+ A ++ +++K + Sbjct: 139 DFFKECDYSM-------IEL-DSKVIHDDKIVMRSKDNMCEPIYLA--LMPTLMKGQVQS 188 Query: 451 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 585 R E ++ + + +G D + L ET+ G Y V + I E+E Sbjct: 189 REENFEIGHTLEEGFDLIALYQETSHGPYAARSVKCIDEISVESE 233 >UniRef50_Q8CA87 Cluster: Adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330017A19 product:hypothetical protein, full insert sequence; n=1; Mus musculus|Rep: Adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330017A19 product:hypothetical protein, full insert sequence - Mus musculus (Mouse) Length = 136 Score = 37.5 bits (83), Expect = 0.33 Identities = 23/75 (30%), Positives = 30/75 (40%) Frame = -1 Query: 335 GGISIPRSPRATMIPSDSAIISSKLTIPW*FSILEMILMFLPFSPRMPRISCSAAPLRMN 156 GG+ P PR + + + L W F L + L F PF +P CSA P R Sbjct: 3 GGVIAPPGPRRRKLQLEQ-LAREPLACLWVFFFLSLSLFFFPFPFSLPSPLCSAGPCRPG 61 Query: 155 DAKIISTPCSTPKSR 111 + P ST R Sbjct: 62 NPHPSCPPPSTAARR 76 >UniRef50_A0IJJ4 Cluster: HpcH/HpaI aldolase; n=2; Bacteria|Rep: HpcH/HpaI aldolase - Serratia proteamaculans 568 Length = 287 Score = 36.3 bits (80), Expect = 0.77 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 4/97 (4%) Frame = +1 Query: 112 LLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESD 291 +L G I S +R+ A + +R GK+ +I IE + + +LD++ A +D Sbjct: 85 MLCGGGTAPGFIVMSMVRSPAEVVFLRETFASAGKHPEIYLTIETVEAITDLDDVAAVAD 144 Query: 292 GIMVARGD----LGIEIPPEKVFLAQKTMIARCNRVG 390 G++ D LG+ I + A++ M+ R G Sbjct: 145 GLIFGSADLAATLGVPITWSGMLAARQAMVLASARHG 181 >UniRef50_Q54CD8 Cluster: Putative RNA helicase; n=2; Dictyostelium discoideum|Rep: Putative RNA helicase - Dictyostelium discoideum AX4 Length = 1091 Score = 35.5 bits (78), Expect = 1.3 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 94 EKDKSDLLF-GVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQ-GMVNL 267 +K S ++F + V+ I R G A I G L + I + +K +HQ G++ + Sbjct: 495 QKKSSTIIFVSTKYHVEFIHILLERAGIASTYIHGYLDPVARKINL-AKFRSHQVGVMVV 553 Query: 268 DEIIAESDGIMVARGDLGIEIPP-EKVFLAQKTMIARCNRVG 390 ++ A I + + + PP EK+F+ + +AR R G Sbjct: 554 TDLAARGIDIPLLDNVINFDFPPKEKIFIHRVGRVARAGRSG 595 >UniRef50_A6RIB2 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 6808 Score = 34.3 bits (75), Expect = 3.1 Identities = 18/48 (37%), Positives = 24/48 (50%) Frame = +3 Query: 348 PRPEDHDRQMQSGWKTSDLCDSNAGIHG*EAPSHQSRDL*RSQRHPRR 491 PR DR+ S +++ D A I E PSHQS+D Q P+R Sbjct: 1164 PRDTIEDREQTSSYRSQDKPSETAQIRE-ETPSHQSKDESHDQNRPKR 1210 >UniRef50_A3LQY4 Cluster: Predicted protein; n=1; Pichia stipitis|Rep: Predicted protein - Pichia stipitis (Yeast) Length = 1931 Score = 34.3 bits (75), Expect = 3.1 Identities = 28/98 (28%), Positives = 46/98 (46%) Frame = +1 Query: 226 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 405 +IS+ ++ +DE+I + DG++ G +EIP E KT + ++ +PV+ Sbjct: 767 VISERATNESKSRVDEVIVDGDGVIEEEGLCRLEIPNE------KTEMEELEKIERPVL- 819 Query: 406 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGE 519 E +R E S V A+ DG D V+ S E Sbjct: 820 EELATEEEDYTESDSRFEFSGV-EAVEDGNDEVVASHE 856 >UniRef50_Q0EZ03 Cluster: Putative uncharacterized protein; n=2; Mariprofundus ferrooxydans PV-1|Rep: Putative uncharacterized protein - Mariprofundus ferrooxydans PV-1 Length = 801 Score = 33.9 bits (74), Expect = 4.1 Identities = 23/73 (31%), Positives = 36/73 (49%) Frame = +1 Query: 433 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF 612 K+ + A+ SD++ L G D M E++ D+P + +H MA + + VI H +L Sbjct: 552 KESTVSPAKFSDLSRYFLSGFDTYM---ESSYLDHPEQVLHLMARLASDFPLVIDHSRLH 608 Query: 613 NDLVSEVKPPIDP 651 SEV P P Sbjct: 609 FVSSSEVVNPDGP 621 >UniRef50_A7TH49 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 394 Score = 33.9 bits (74), Expect = 4.1 Identities = 15/55 (27%), Positives = 30/55 (54%) Frame = +1 Query: 211 GKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 G + SK+ + +N+ + +S+G ++ G+ E+P EK++L K +AR Sbjct: 65 GTERSVKSKVTKPKSQLNITNMTYQSNGDYLSHGEYLNELPKEKIYLENKLELAR 119 >UniRef50_Q9LSA0 Cluster: Emb|CAB62463.1; n=3; Arabidopsis thaliana|Rep: Emb|CAB62463.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 653 Score = 33.5 bits (73), Expect = 5.4 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Frame = -1 Query: 194 PRISCSAAPLRMNDAKIISTPCS--TPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIP 27 P +SCS +P R + ++S PCS P SD+ T R P +P +D S P Sbjct: 350 PSVSCSPSPTRSDSHALVSHPCSRHLPPHPSDI---PTGRRKESYPEEYSPCQDFSPP 404 >UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|Rep: HDC11342 - Drosophila melanogaster (Fruit fly) Length = 1115 Score = 33.5 bits (73), Expect = 5.4 Identities = 13/23 (56%), Positives = 17/23 (73%) Frame = -1 Query: 140 STPCSTPKSRSDLSFSETAGRST 72 +TPCSTP+ DLSF E A ++T Sbjct: 949 TTPCSTPRGEDDLSFKEGAPKTT 971 >UniRef50_P23522 Cluster: 2-dehydro-3-deoxyglucarate aldolase; n=27; Proteobacteria|Rep: 2-dehydro-3-deoxyglucarate aldolase - Escherichia coli (strain K12) Length = 256 Score = 33.5 bits (73), Expect = 5.4 Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%) Frame = +1 Query: 205 EKGKNIKIISKIENHQGMVNLDEIIAES--DGIMVARGDL 318 + KNI I+ +IE+ QG+ N+D I A DGI V DL Sbjct: 141 QSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDL 180 >UniRef50_Q6VZK4 Cluster: CNPV143 ankyrin repeat protein; n=1; Canarypox virus|Rep: CNPV143 ankyrin repeat protein - Canarypox virus (CNPV) Length = 671 Score = 33.1 bits (72), Expect = 7.1 Identities = 22/66 (33%), Positives = 33/66 (50%) Frame = +1 Query: 79 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGM 258 +PA+S D L F ++ GVD+ + N A + I EK K IK+I + N+ Sbjct: 172 IPALSNNDNEMLQFLIDSGVDINQKNRYGNTALHYAI-----EKNKKIKLIETLVNNNAD 226 Query: 259 VNLDEI 276 VN +I Sbjct: 227 VNATDI 232 >UniRef50_Q893T5 Cluster: Flagellar hook-associated protein 1; n=1; Clostridium tetani|Rep: Flagellar hook-associated protein 1 - Clostridium tetani Length = 579 Score = 33.1 bits (72), Expect = 7.1 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = -3 Query: 462 DLGSGGTGLLNHGFQHLSRTDHWFSNPIASGDHGLLGEEYLFWRDLDTQISASNHDTI 289 +LG GT + + F L+ ++ FS P +G LLG+ Y W++L Q +SN T+ Sbjct: 88 ELGVQGTYVERNKF--LNEIENIFSEPSETGISTLLGKFYKGWQELSKQPHSSNARTV 143 >UniRef50_Q5YWM7 Cluster: Putative uncharacterized protein; n=1; Nocardia farcinica|Rep: Putative uncharacterized protein - Nocardia farcinica Length = 430 Score = 33.1 bits (72), Expect = 7.1 Identities = 14/57 (24%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Frame = +1 Query: 124 VEQGVDMIF--ASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAES 288 ++ G ++++ A N H +RG+LG G+ I ++ +G ++D+I+A + Sbjct: 125 LDDGDEILYSPADHASNVLPWHHLRGLLGRAGRRIDLVPYATTRRGTADIDDILARA 181 >UniRef50_Q1NHC0 Cluster: Putative uncharacterized protein; n=1; Sphingomonas sp. SKA58|Rep: Putative uncharacterized protein - Sphingomonas sp. SKA58 Length = 333 Score = 33.1 bits (72), Expect = 7.1 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Frame = -3 Query: 609 ELPVPDYSFSLLANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSGGTGLLN 430 + PVP +A +N + + G PG ++ DG G V +G G TG+ Sbjct: 21 DTPVPGPGEVRVALRAASINHRELFITHGQYPGMTVPITLGCDGAGVVDMIGEGVTGVRE 80 Query: 429 HGFQHLSRTDHWFSNPIA-SGDHGLLG 352 L +W SN A + D GLLG Sbjct: 81 GDEVVLYPARNWGSNRHAPAADFGLLG 107 >UniRef50_Q0YHY4 Cluster: Protein-glutamate O-methyltransferase; n=2; Geobacter|Rep: Protein-glutamate O-methyltransferase - Geobacter sp. FRC-32 Length = 300 Score = 33.1 bits (72), Expect = 7.1 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 8/98 (8%) Frame = +1 Query: 325 EIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI--SDVANAILDGAD 498 E PP + + + A C+ +P A +LES+ + P+ EI D+++A L A+ Sbjct: 107 ESPPSASIMKIRVLCAGCSTGEEPYSIAMALLESL-RYPKAWDVEILAGDLSSACLKKAE 165 Query: 499 CVMLSGETAKGDYP------VECVHTMANICKEAEAVI 594 GE KG P +ECV A + +E + +I Sbjct: 166 TGFYEGERLKGLPPAFREKYLECVDGGAMVREEVKKLI 203 >UniRef50_Q04GL6 Cluster: RecG-like helicase; n=5; Lactobacillales|Rep: RecG-like helicase - Oenococcus oeni (strain BAA-331 / PSU-1) Length = 676 Score = 33.1 bits (72), Expect = 7.1 Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Frame = +1 Query: 172 AALHEIRGILG--EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKV 345 A LH++RG +G +K ++S + G+ ++ I++ +DG +A DL + P + + Sbjct: 555 AQLHQLRGRVGRGKKQSYAILVSDPKTQYGIDRMEAIVSTNDGFALAEKDLKLRGPGDVI 614 Query: 346 FLAQKTM 366 + Q M Sbjct: 615 GIKQAGM 621 >UniRef50_A0Y985 Cluster: Zinc-containing alcohol dehydrogenase superfamily protein; n=1; marine gamma proteobacterium HTCC2143|Rep: Zinc-containing alcohol dehydrogenase superfamily protein - marine gamma proteobacterium HTCC2143 Length = 324 Score = 33.1 bits (72), Expect = 7.1 Identities = 19/48 (39%), Positives = 26/48 (54%) Frame = -3 Query: 579 LLANVGHGVNTLDRIVALGSLPGEHHAVSSVEDGVGYVRDLGSGGTGL 436 L+ N G N +D + G P + AV VE G G V ++G+G TGL Sbjct: 32 LVRNTVAGFNMIDTYMRKGLYPVKFPAVMGVE-GAGVVEEVGAGVTGL 78 >UniRef50_Q949D7 Cluster: Putative uncharacterized protein C555ERIPDS; n=4; Oryza sativa|Rep: Putative uncharacterized protein C555ERIPDS - Oryza sativa (Rice) Length = 691 Score = 33.1 bits (72), Expect = 7.1 Identities = 19/65 (29%), Positives = 26/65 (40%) Frame = -1 Query: 203 PRMPRISCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPA 24 P P +AA +M K + T S P+S + GR+ G G T + P Sbjct: 319 PSHPMTQQNAAAQQMQQNKDVKTNASNPRSNAKQDLGTGKGRAVGTGGSSTKSQGKQFPL 378 Query: 23 LSCCS 9 LS S Sbjct: 379 LSAAS 383 >UniRef50_Q8F846 Cluster: Putative uncharacterized protein; n=2; Leptospira interrogans|Rep: Putative uncharacterized protein - Leptospira interrogans Length = 892 Score = 32.7 bits (71), Expect = 9.4 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Frame = +1 Query: 199 LGEKGKNIK-IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 375 LG++ KN K ++ + + LDE +S G LG ++ PE++ K + Sbjct: 575 LGQRDKNGKPVLYSLPGSKSGDVLDESACQSHGPATVLASLGFKMTPEQINQYGKLNV-- 632 Query: 376 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAIL 486 + + V A QML KPRP+ I ++++ +L Sbjct: 633 --MITRMVAEAGQMLP---HKPRPSEMSIQEISDLVL 664 >UniRef50_A3XHP8 Cluster: Putative uncharacterized protein; n=1; Leeuwenhoekiella blandensis MED217|Rep: Putative uncharacterized protein - Leeuwenhoekiella blandensis MED217 Length = 526 Score = 32.7 bits (71), Expect = 9.4 Identities = 14/43 (32%), Positives = 23/43 (53%) Frame = +1 Query: 217 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKV 345 N +I K+ + G N +++ ESD + +L I IPPE + Sbjct: 391 NFPVIYKVYSRNGWYNKGDLLFESDATNLCAQELTITIPPESI 433 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 706,358,822 Number of Sequences: 1657284 Number of extensions: 15066243 Number of successful extensions: 52092 Number of sequences better than 10.0: 187 Number of HSP's better than 10.0 without gapping: 49586 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 51961 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 58677691418 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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