Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-2062
(750 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC027993-1|AAH27993.1| 627|Homo sapiens CAPN9 protein protein. 120 7e-27
AY874864-1|AAW49735.1| 690|Homo sapiens calpain 9 protein. 120 7e-27
AL591291-1|CAI17214.1| 690|Homo sapiens calpain 9 protein. 120 7e-27
AL512328-2|CAI14865.1| 690|Homo sapiens calpain 9 protein. 120 7e-27
AF022799-1|AAB80762.1| 690|Homo sapiens digestive tract-specifi... 120 7e-27
X04366-1|CAA27881.1| 714|Homo sapiens protein ( Human mRNA for ... 114 3e-25
BC017200-1|AAH17200.1| 714|Homo sapiens calpain 1, (mu/I) large... 114 3e-25
BC008751-1|AAH08751.1| 714|Homo sapiens calpain 1, (mu/I) large... 114 3e-25
AY796340-1|AAV41878.1| 714|Homo sapiens calpain 1, (mu/I) large... 114 3e-25
AY550975-1|AAT52221.1| 714|Homo sapiens cell proliferation-indu... 114 3e-25
BC075862-1|AAH75862.1| 714|Homo sapiens CAPN1 protein protein. 114 4e-25
M23254-1|AAA35645.1| 700|Homo sapiens neutral protease large su... 113 5e-25
BC021303-1|AAH21303.1| 700|Homo sapiens calpain 2, (m/II) large... 113 5e-25
BC011828-1|AAH11828.1| 610|Homo sapiens Unknown (protein for IM... 113 5e-25
BC007686-1|AAH07686.1| 610|Homo sapiens Unknown (protein for IM... 113 5e-25
AY835586-1|AAV80421.1| 700|Homo sapiens calpain 2, (m/II) large... 113 5e-25
AF261089-1|AAF99682.1| 700|Homo sapiens calpain large polypepti... 113 5e-25
AB209855-1|BAD93092.1| 729|Homo sapiens Calpain 2, large [catal... 113 5e-25
AL591291-2|CAI17215.1| 664|Homo sapiens calpain 9 protein. 110 5e-24
AL512328-3|CAI14866.1| 664|Homo sapiens calpain 9 protein. 110 5e-24
AB038463-1|BAA92137.1| 664|Homo sapiens GC36 protein. 110 5e-24
X85030-1|CAA59403.1| 821|Homo sapiens calpain protein. 104 4e-22
BC146672-1|AAI46673.1| 821|Homo sapiens calpain 3, (p94) protein. 104 4e-22
BC146649-1|AAI46650.1| 821|Homo sapiens calpain 3, (p94) protein. 104 4e-22
AY902237-1|AAW69391.1| 821|Homo sapiens calpain 3, (p94) protein. 104 4e-22
AF209502-1|AAL40183.1| 821|Homo sapiens calpain protein. 104 4e-22
AF127765-1|AAD28254.3| 729|Homo sapiens calpain 3 protein. 104 4e-22
AF127764-1|AAD28253.1| 815|Homo sapiens calpain 3 protein. 104 4e-22
AB117940-1|BAD16649.1| 728|Homo sapiens hUp84 protein. 104 4e-22
BC033733-1|AAH33733.1| 702|Homo sapiens calpain 11 protein. 98 3e-20
AL365192-3|CAI20532.2| 739|Homo sapiens calpain 11 protein. 98 3e-20
AJ242832-1|CAB52137.1| 702|Homo sapiens calpain protein. 98 3e-20
Y10552-1|CAA71584.1| 634|Homo sapiens CAPN5 protein protein. 75 4e-13
BC018123-1|AAH18123.1| 640|Homo sapiens calpain 5 protein. 75 4e-13
AK128124-1|BAC87282.1| 680|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AB209087-1|BAD92324.1| 678|Homo sapiens Hypothetical protein FL... 74 5e-13
U94346-1|AAC51869.1| 639|Homo sapiens calpain-like protease pro... 73 8e-13
CR628412-1|CAM28354.1| 437|Homo sapiens calpain 8 protein. 71 6e-12
AB117941-1|BAD16650.1| 426|Homo sapiens hUp49 protein. 68 3e-11
BC007553-1|AAH07553.2| 672|Homo sapiens calpain 10 protein. 60 8e-09
BC004260-1|AAH04260.1| 672|Homo sapiens calpain 10 protein. 60 8e-09
AK074807-1|BAC11220.1| 672|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AF089088-1|AAG17966.1| 672|Homo sapiens calpain-like protease C... 60 8e-09
AC124862-2|AAX88944.1| 672|Homo sapiens unknown protein. 60 8e-09
AB058748-1|BAB47474.1| 705|Homo sapiens KIAA1845 protein protein. 60 8e-09
CR628412-2|CAM28355.1| 381|Homo sapiens calpain 8 protein. 56 1e-07
AF089090-1|AAG17968.1| 544|Homo sapiens calpain-like protease C... 56 2e-07
AF089092-1|AAG17970.1| 513|Homo sapiens calpain-like protease C... 54 7e-07
AK127398-1|BAC86959.1| 719|Homo sapiens protein ( Homo sapiens ... 52 3e-06
AF089091-1|AAG17969.1| 517|Homo sapiens calpain-like protease C... 51 5e-06
BT007322-1|AAP35986.1| 309|Homo sapiens calpain 3, (p94) protein. 48 4e-05
BC003169-1|AAH03169.1| 309|Homo sapiens calpain 3, (p94) protein. 48 4e-05
AF089093-1|AAG17971.1| 444|Homo sapiens calpain-like protease C... 46 1e-04
AK124751-1|BAC85936.1| 210|Homo sapiens protein ( Homo sapiens ... 46 2e-04
BC056202-1|AAH56202.1| 813|Homo sapiens calpain 7 protein. 40 0.013
AB028639-1|BAA78730.1| 813|Homo sapiens PalBH protein. 40 0.013
AF089096-1|AAG17974.1| 138|Homo sapiens calpain-like protease C... 33 0.83
L37378-1|AAA74451.1| 1108|Homo sapiens guanylyl cyclase protein. 32 1.9
AL031387-4|CAB41303.1| 1108|Homo sapiens guanylate cyclase 2F, r... 32 1.9
>BC027993-1|AAH27993.1| 627|Homo sapiens CAPN9 protein protein.
Length = 627
Score = 120 bits (288), Expect = 7e-27
Identities = 77/231 (33%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM---IASKGVWMLFSDFQRLFPRI 172
LIR+R P G E S + W+++ E+ RL + WM F DF+ F ++
Sbjct: 210 LIRIRNPWGQVEWNGSWSD-SSPEWRSVGPAEQKRLCHTALDDGEFWMAFQDFKAHFDKV 268
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + L KW++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E
Sbjct: 269 EICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEK 324
Query: 353 D------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINS 493
D + +++L Q + K IG+++Y+ P E N+ FF+ S S
Sbjct: 325 DEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARS 383
Query: 494 Q-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K + +D
Sbjct: 384 KTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMD 434
>AY874864-1|AAW49735.1| 690|Homo sapiens calpain 9 protein.
Length = 690
Score = 120 bits (288), Expect = 7e-27
Identities = 77/231 (33%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM---IASKGVWMLFSDFQRLFPRI 172
LIR+R P G E S + W+++ E+ RL + WM F DF+ F ++
Sbjct: 273 LIRIRNPWGQVEWNGSWSD-SSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKV 331
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + L KW++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E
Sbjct: 332 EICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEK 387
Query: 353 D------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINS 493
D + +++L Q + K IG+++Y+ P E N+ FF+ S S
Sbjct: 388 DEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARS 446
Query: 494 Q-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K + +D
Sbjct: 447 KTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMD 497
>AL591291-1|CAI17214.1| 690|Homo sapiens calpain 9 protein.
Length = 690
Score = 120 bits (288), Expect = 7e-27
Identities = 77/231 (33%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM---IASKGVWMLFSDFQRLFPRI 172
LIR+R P G E S + W+++ E+ RL + WM F DF+ F ++
Sbjct: 273 LIRIRNPWGQVEWNGSWSD-SSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKV 331
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + L KW++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E
Sbjct: 332 EICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEK 387
Query: 353 D------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINS 493
D + +++L Q + K IG+++Y+ P E N+ FF+ S S
Sbjct: 388 DEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARS 446
Query: 494 Q-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K + +D
Sbjct: 447 KTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMD 497
>AL512328-2|CAI14865.1| 690|Homo sapiens calpain 9 protein.
Length = 690
Score = 120 bits (288), Expect = 7e-27
Identities = 77/231 (33%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM---IASKGVWMLFSDFQRLFPRI 172
LIR+R P G E S + W+++ E+ RL + WM F DF+ F ++
Sbjct: 273 LIRIRNPWGQVEWNGSWSD-SSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKV 331
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + L KW++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E
Sbjct: 332 EICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEK 387
Query: 353 D------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINS 493
D + +++L Q + K IG+++Y+ P E N+ FF+ S S
Sbjct: 388 DEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARS 446
Query: 494 Q-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K + +D
Sbjct: 447 KTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMD 497
>AF022799-1|AAB80762.1| 690|Homo sapiens digestive tract-specific
calpain protein.
Length = 690
Score = 120 bits (288), Expect = 7e-27
Identities = 77/231 (33%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM---IASKGVWMLFSDFQRLFPRI 172
LIR+R P G E S + W+++ E+ RL + WM F DF+ F ++
Sbjct: 273 LIRIRNPWGQVEWNGSWSD-SSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKV 331
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + L KW++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E
Sbjct: 332 EICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEK 387
Query: 353 D------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINS 493
D + +++L Q + K IG+++Y+ P E N+ FF+ S S
Sbjct: 388 DEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARS 446
Query: 494 Q-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K + +D
Sbjct: 447 KTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMD 497
>X04366-1|CAA27881.1| 714|Homo sapiens protein ( Human mRNA for
calcium activated neutral protease large subunit
(muCANP, calpain, EC 3.4.22.17). ).
Length = 714
Score = 114 bits (275), Expect = 3e-25
Identities = 77/244 (31%), Positives = 116/244 (47%), Gaps = 26/244 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E + ++ W + YER +L + + WM F DF R F R+E
Sbjct: 291 LIRMRNPWGEVEWTGAWSD-SSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE 349
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L + ++ +KW +++G W+RG +AGGCRNY F NPQ +I L+E D
Sbjct: 350 ICNLTPDALKSRTI----RKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETD 405
Query: 356 T-------------VIISLNQHSIMEPK------VIGFSVYKMPKFL-----TETANQMF 463
V+ + +H E + IGF+VY++P L F
Sbjct: 406 DPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFF 465
Query: 464 FKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ Q+ N R+VS R +L G Y+++P+TFEP +E F L +S K LD
Sbjct: 466 LANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELD 525
Query: 644 DPPQ 655
D Q
Sbjct: 526 DQIQ 529
>BC017200-1|AAH17200.1| 714|Homo sapiens calpain 1, (mu/I) large
subunit protein.
Length = 714
Score = 114 bits (275), Expect = 3e-25
Identities = 77/244 (31%), Positives = 116/244 (47%), Gaps = 26/244 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E + ++ W + YER +L + + WM F DF R F R+E
Sbjct: 291 LIRMRNPWGEVEWTGAWSD-SSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE 349
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L + ++ +KW +++G W+RG +AGGCRNY F NPQ +I L+E D
Sbjct: 350 ICNLTPDALKSRTI----RKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETD 405
Query: 356 T-------------VIISLNQHSIMEPK------VIGFSVYKMPKFL-----TETANQMF 463
V+ + +H E + IGF+VY++P L F
Sbjct: 406 DPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFF 465
Query: 464 FKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ Q+ N R+VS R +L G Y+++P+TFEP +E F L +S K LD
Sbjct: 466 LANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELD 525
Query: 644 DPPQ 655
D Q
Sbjct: 526 DQIQ 529
>BC008751-1|AAH08751.1| 714|Homo sapiens calpain 1, (mu/I) large
subunit protein.
Length = 714
Score = 114 bits (275), Expect = 3e-25
Identities = 77/244 (31%), Positives = 116/244 (47%), Gaps = 26/244 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E + ++ W + YER +L + + WM F DF R F R+E
Sbjct: 291 LIRMRNPWGEVEWTGAWSD-SSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE 349
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L + ++ +KW +++G W+RG +AGGCRNY F NPQ +I L+E D
Sbjct: 350 ICNLTPDALKSRTI----RKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETD 405
Query: 356 T-------------VIISLNQHSIMEPK------VIGFSVYKMPKFL-----TETANQMF 463
V+ + +H E + IGF+VY++P L F
Sbjct: 406 DPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFF 465
Query: 464 FKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ Q+ N R+VS R +L G Y+++P+TFEP +E F L +S K LD
Sbjct: 466 LANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELD 525
Query: 644 DPPQ 655
D Q
Sbjct: 526 DQIQ 529
>AY796340-1|AAV41878.1| 714|Homo sapiens calpain 1, (mu/I) large
subunit protein.
Length = 714
Score = 114 bits (275), Expect = 3e-25
Identities = 77/244 (31%), Positives = 116/244 (47%), Gaps = 26/244 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E + ++ W + YER +L + + WM F DF R F R+E
Sbjct: 291 LIRMRNPWGEVEWTGAWSD-SSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE 349
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L + ++ +KW +++G W+RG +AGGCRNY F NPQ +I L+E D
Sbjct: 350 ICNLTPDALKSRTI----RKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETD 405
Query: 356 T-------------VIISLNQHSIMEPK------VIGFSVYKMPKFL-----TETANQMF 463
V+ + +H E + IGF+VY++P L F
Sbjct: 406 DPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFF 465
Query: 464 FKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ Q+ N R+VS R +L G Y+++P+TFEP +E F L +S K LD
Sbjct: 466 LANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELD 525
Query: 644 DPPQ 655
D Q
Sbjct: 526 DQIQ 529
>AY550975-1|AAT52221.1| 714|Homo sapiens cell proliferation-inducing
protein 30 protein.
Length = 714
Score = 114 bits (275), Expect = 3e-25
Identities = 77/244 (31%), Positives = 116/244 (47%), Gaps = 26/244 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E + ++ W + YER +L + + WM F DF R F R+E
Sbjct: 291 LIRMRNPWGEVEWTGAWSD-SSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE 349
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L + ++ +KW +++G W+RG +AGGCRNY F NPQ +I L+E D
Sbjct: 350 ICNLTPDALKSRTI----RKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETD 405
Query: 356 T-------------VIISLNQHSIMEPK------VIGFSVYKMPKFL-----TETANQMF 463
V+ + +H E + IGF+VY++P L F
Sbjct: 406 DPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFF 465
Query: 464 FKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ Q+ N R+VS R +L G Y+++P+TFEP +E F L +S K LD
Sbjct: 466 LANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELD 525
Query: 644 DPPQ 655
D Q
Sbjct: 526 DQIQ 529
>BC075862-1|AAH75862.1| 714|Homo sapiens CAPN1 protein protein.
Length = 714
Score = 114 bits (274), Expect = 4e-25
Identities = 77/244 (31%), Positives = 116/244 (47%), Gaps = 26/244 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E + ++ W + YER +L + + WM F DF R F R+E
Sbjct: 291 LIRMRNPWGEVEWTGAWSD-SSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE 349
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L + ++ +KW +++G W+RG +AGGCRNY F NPQ +I L+E D
Sbjct: 350 ICNLTPDALKSRTI----RKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETD 405
Query: 356 T-------------VIISLNQHSIME------PKVIGFSVYKMPKFL-----TETANQMF 463
V+ + +H E + IGF+VY++P L F
Sbjct: 406 DPDDYGDRESGCSFVLALMQKHRRRERPFGRDMETIGFAVYEVPPELVGQPAVHLKRDFF 465
Query: 464 FKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLD 643
+ Q+ N R+VS R +L G Y+++P+TFEP +E F L +S K LD
Sbjct: 466 LANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELD 525
Query: 644 DPPQ 655
D Q
Sbjct: 526 DQIQ 529
>M23254-1|AAA35645.1| 700|Homo sapiens neutral protease large
subunit protein.
Length = 700
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 281 LIRIRNPWGEVEWT-GRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 340 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 395
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 396 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 455
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 456 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 514
>BC021303-1|AAH21303.1| 700|Homo sapiens calpain 2, (m/II) large
subunit protein.
Length = 700
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 281 LIRIRNPWGEVEWT-GRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 340 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 395
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 396 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 455
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 456 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 514
>BC011828-1|AAH11828.1| 610|Homo sapiens Unknown (protein for
IMAGE:3833113) protein.
Length = 610
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 281 LIRIRNPWGEVEWT-GRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 340 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 395
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 396 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 455
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 456 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 514
>BC007686-1|AAH07686.1| 610|Homo sapiens Unknown (protein for
IMAGE:3637421) protein.
Length = 610
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 281 LIRIRNPWGEVEWT-GRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 340 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 395
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 396 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 455
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 456 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 514
>AY835586-1|AAV80421.1| 700|Homo sapiens calpain 2, (m/II) large
subunit protein.
Length = 700
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 281 LIRIRNPWGEVEWT-GRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 340 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 395
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 396 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 455
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 456 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 514
>AF261089-1|AAF99682.1| 700|Homo sapiens calpain large polypeptide
L2 protein.
Length = 700
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 281 LIRIRNPWGEVEWT-GRWNDSCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 340 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 395
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 396 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 455
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 456 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 514
>AB209855-1|BAD93092.1| 729|Homo sapiens Calpain 2, large [catalytic]
subunit precursor variant protein.
Length = 729
Score = 113 bits (273), Expect = 5e-25
Identities = 80/239 (33%), Positives = 119/239 (49%), Gaps = 24/239 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
LIR+R P G E W TI ER RL + WM FSDF R + R+E
Sbjct: 310 LIRIRNPWGEVEWT-GRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLE 368
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L +T L+ +KW++ G W+RG +AGGCRNY N F NPQ I L E D
Sbjct: 369 ICNLTPDT----LTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEED 424
Query: 356 ----------TVIISLNQ-HSIMEPKV------IGFSVYKMPKFLTETAN----QMFFKR 472
T ++ L Q H + K+ IGF +Y++P+ L+ N + FF
Sbjct: 425 EDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT 484
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
++ S + N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 485 NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 543
>AL591291-2|CAI17215.1| 664|Homo sapiens calpain 9 protein.
Length = 664
Score = 110 bits (265), Expect = 5e-24
Identities = 64/184 (34%), Positives = 103/184 (55%), Gaps = 14/184 (7%)
Frame = +2
Query: 134 MLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFF 313
M F DF+ F ++E+ +L + L KW++ +HQG W RG +AGGCRN+++ F
Sbjct: 293 MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTF 348
Query: 314 HTNPQVQIMLNEPD------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETAN 454
TNPQ+++ L E D + +++L Q + K IG+++Y+ P E N
Sbjct: 349 WTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLN 407
Query: 455 QMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKM 631
+ FF+ S S+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K
Sbjct: 408 KDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAIT 467
Query: 632 KVLD 643
+ +D
Sbjct: 468 RDMD 471
>AL512328-3|CAI14866.1| 664|Homo sapiens calpain 9 protein.
Length = 664
Score = 110 bits (265), Expect = 5e-24
Identities = 64/184 (34%), Positives = 103/184 (55%), Gaps = 14/184 (7%)
Frame = +2
Query: 134 MLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFF 313
M F DF+ F ++E+ +L + L KW++ +HQG W RG +AGGCRN+++ F
Sbjct: 293 MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTF 348
Query: 314 HTNPQVQIMLNEPD------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETAN 454
TNPQ+++ L E D + +++L Q + K IG+++Y+ P E N
Sbjct: 349 WTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLN 407
Query: 455 QMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKM 631
+ FF+ S S+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K
Sbjct: 408 KDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAIT 467
Query: 632 KVLD 643
+ +D
Sbjct: 468 RDMD 471
>AB038463-1|BAA92137.1| 664|Homo sapiens GC36 protein.
Length = 664
Score = 110 bits (265), Expect = 5e-24
Identities = 64/184 (34%), Positives = 103/184 (55%), Gaps = 14/184 (7%)
Frame = +2
Query: 134 MLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFF 313
M F DF+ F ++E+ +L + L KW++ +HQG W RG +AGGCRN+++ F
Sbjct: 293 MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTF 348
Query: 314 HTNPQVQIMLNEPD------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETAN 454
TNPQ+++ L E D + +++L Q + K IG+++Y+ P E N
Sbjct: 349 WTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPD-KDEHLN 407
Query: 455 QMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKM 631
+ FF+ S S+ + N R+VS R +L G Y+++P+TFEP +EA F L I+S K
Sbjct: 408 KDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAIT 467
Query: 632 KVLD 643
+ +D
Sbjct: 468 RDMD 471
>X85030-1|CAA59403.1| 821|Homo sapiens calpain protein.
Length = 821
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 353 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 411
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 412 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 467
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 468 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 527
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 528 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 577
>BC146672-1|AAI46673.1| 821|Homo sapiens calpain 3, (p94) protein.
Length = 821
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 353 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 411
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 412 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 467
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 468 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 527
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 528 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 577
>BC146649-1|AAI46650.1| 821|Homo sapiens calpain 3, (p94) protein.
Length = 821
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 353 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 411
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 412 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 467
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 468 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 527
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 528 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 577
>AY902237-1|AAW69391.1| 821|Homo sapiens calpain 3, (p94) protein.
Length = 821
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 353 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 411
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 412 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 467
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 468 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 527
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 528 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 577
>AF209502-1|AAL40183.1| 821|Homo sapiens calpain protein.
Length = 821
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 353 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 411
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 412 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 467
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 468 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 527
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 528 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 577
>AF127765-1|AAD28254.3| 729|Homo sapiens calpain 3 protein.
Length = 729
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 305 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 363
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 364 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 419
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 420 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 479
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 480 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 529
>AF127764-1|AAD28253.1| 815|Homo sapiens calpain 3 protein.
Length = 815
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 353 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 411
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 412 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 467
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 468 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 527
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 528 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 577
>AB117940-1|BAD16649.1| 728|Homo sapiens hUp84 protein.
Length = 728
Score = 104 bits (249), Expect = 4e-22
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 24/230 (10%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 266 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 324
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 325 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 380
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKR 472
D + +++L Q + + + IGF++Y++PK + + FF
Sbjct: 381 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLY 440
Query: 473 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 441 NASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 490
>BC033733-1|AAH33733.1| 702|Homo sapiens calpain 11 protein.
Length = 702
Score = 98.3 bits (234), Expect = 3e-20
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 25/197 (12%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
WM + DF F +E+ +L +T LS K W ++G W+RG SAGGCRN+
Sbjct: 322 WMSYQDFLNNFTLLEICNLTPDT----LSGDYKSYWHTTFYEGSWRRGSSAGGCRNHPGT 377
Query: 311 FHTNPQVQIMLNEPD-------------TVIISLNQ----HSIMEP---KVIGFSVYKMP 430
F TNPQ +I L E D T +++L Q H+ + + IGF +Y +P
Sbjct: 378 FWTNPQFKISLPEGDDPEDDAEGNVVACTCLVALMQKNWRHARQQGAQLQTIGFVLYAVP 437
Query: 431 KFL-----TETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQF 595
K + F K + +TNSR+VS + +L G Y+I+P+TFEP +A F
Sbjct: 438 KEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPSTFEPHRDADF 497
Query: 596 TLXIYSNKPLKMKVLDD 646
L +++ K + LD+
Sbjct: 498 LLRVFTEKHSESWELDE 514
>AL365192-3|CAI20532.2| 739|Homo sapiens calpain 11 protein.
Length = 739
Score = 98.3 bits (234), Expect = 3e-20
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 25/197 (12%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
WM + DF F +E+ +L +T LS K W ++G W+RG SAGGCRN+
Sbjct: 359 WMSYQDFLNNFTLLEICNLTPDT----LSGDYKSYWHTTFYEGSWRRGSSAGGCRNHPGT 414
Query: 311 FHTNPQVQIMLNEPD-------------TVIISLNQ----HSIMEP---KVIGFSVYKMP 430
F TNPQ +I L E D T +++L Q H+ + + IGF +Y +P
Sbjct: 415 FWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALMQKNWRHARQQGAQLQTIGFVLYAVP 474
Query: 431 KFL-----TETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQF 595
K + F K + +TNSR+VS + +L G Y+I+P+TFEP +A F
Sbjct: 475 KEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPSTFEPHRDADF 534
Query: 596 TLXIYSNKPLKMKVLDD 646
L +++ K + LD+
Sbjct: 535 LLRVFTEKHSESWELDE 551
>AJ242832-1|CAB52137.1| 702|Homo sapiens calpain protein.
Length = 702
Score = 98.3 bits (234), Expect = 3e-20
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 25/197 (12%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
WM + DF F +E+ +L +T LS K W ++G W+RG SAGGCRN+
Sbjct: 322 WMSYQDFLNNFTLLEICNLTPDT----LSGDYKSYWHTTFYEGSWRRGSSAGGCRNHPGT 377
Query: 311 FHTNPQVQIMLNEPD-------------TVIISLNQ----HSIMEP---KVIGFSVYKMP 430
F TNPQ +I L E D T +++L Q H+ + + IGF +Y +P
Sbjct: 378 FWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALMQKNWRHARQQGAQLQTIGFVLYAVP 437
Query: 431 KFL-----TETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQF 595
K + F K + +TNSR+VS + +L G Y+I+P+TFEP +A F
Sbjct: 438 KEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPSTFEPHRDADF 497
Query: 596 TLXIYSNKPLKMKVLDD 646
L +++ K + LD+
Sbjct: 498 LLRVFTEKHSESWELDE 514
>Y10552-1|CAA71584.1| 634|Homo sapiens CAPN5 protein protein.
Length = 634
Score = 74.5 bits (175), Expect = 4e-13
Identities = 70/245 (28%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 2 LIRLRRPLGHGET--PISHIVLXTALWKTIPQYERXRLMIASKG---VWMLFSDFQRLFP 166
+IRLR P G E P S + W+ + + ER ++ + + WM F D R F
Sbjct: 279 MIRLRNPWGEREWNGPWSDT---SEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFT 335
Query: 167 RIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQV 331
I + TS LS + W+ G W R GGC N+ + F NPQ
Sbjct: 336 DIIKCRV-INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQY 390
Query: 332 QIMLNEP-DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKST 484
+ +P D V+I + Q + IGF +YK+ + + + K S
Sbjct: 391 IFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI 450
Query: 485 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKV--LDDPPQM 658
Y NSR V R G Y+I+PTTFEP +F L ++++ P + LD+PP
Sbjct: 451 ----YINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHT 506
Query: 659 TKAAL 673
++L
Sbjct: 507 CWSSL 511
>BC018123-1|AAH18123.1| 640|Homo sapiens calpain 5 protein.
Length = 640
Score = 74.5 bits (175), Expect = 4e-13
Identities = 70/245 (28%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 2 LIRLRRPLGHGET--PISHIVLXTALWKTIPQYERXRLMIASKG---VWMLFSDFQRLFP 166
+IRLR P G E P S + W+ + + ER ++ + + WM F D R F
Sbjct: 279 MIRLRNPWGEREWNGPWSDT---SEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFT 335
Query: 167 RIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQV 331
I + TS LS + W+ G W R GGC N+ + F NPQ
Sbjct: 336 DIIKCRV-INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQY 390
Query: 332 QIMLNEP-DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKST 484
+ +P D V+I + Q + IGF +YK+ + + + K S
Sbjct: 391 IFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI 450
Query: 485 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKV--LDDPPQM 658
Y NSR V R G Y+I+PTTFEP +F L ++++ P + LD+PP
Sbjct: 451 ----YINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHT 506
Query: 659 TKAAL 673
++L
Sbjct: 507 CWSSL 511
>AK128124-1|BAC87282.1| 680|Homo sapiens protein ( Homo sapiens cDNA
FLJ46245 fis, clone TESTI4020596, highly similar to Homo
sapiens calpain 5 (CAPN5). ).
Length = 680
Score = 74.5 bits (175), Expect = 4e-13
Identities = 70/245 (28%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 2 LIRLRRPLGHGET--PISHIVLXTALWKTIPQYERXRLMIASKG---VWMLFSDFQRLFP 166
+IRLR P G E P S + W+ + + ER ++ + + WM F D R F
Sbjct: 319 MIRLRNPWGEREWNGPWSDT---SEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFT 375
Query: 167 RIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQV 331
I + TS LS + W+ G W R GGC N+ + F NPQ
Sbjct: 376 DIIKCRV-INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQY 430
Query: 332 QIMLNEP-DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKST 484
+ +P D V+I + Q + IGF +YK+ + + + K S
Sbjct: 431 IFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI 490
Query: 485 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKV--LDDPPQM 658
Y NSR V R G Y+I+PTTFEP +F L ++++ P + LD+PP
Sbjct: 491 ----YINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHT 546
Query: 659 TKAAL 673
++L
Sbjct: 547 CWSSL 551
>AB209087-1|BAD92324.1| 678|Homo sapiens Hypothetical protein
FLJ46245 variant protein.
Length = 678
Score = 74.1 bits (174), Expect = 5e-13
Identities = 70/245 (28%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 2 LIRLRRPLGHGET--PISHIVLXTALWKTIPQYERXRLMIASKG---VWMLFSDFQRLFP 166
+IRLR P G E P S + W+ + + ER ++ + + WM F D R F
Sbjct: 317 MIRLRNPWGEREWNGPWSDT---SEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFT 373
Query: 167 RIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQV 331
I + TS LS + W+ G W R GGC N+ + F NPQ
Sbjct: 374 DIIKCRV-INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQY 428
Query: 332 QIMLNEP-DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKST 484
+ +P D V+I + Q + IGF +YK+ + + + K
Sbjct: 429 IFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHK----A 484
Query: 485 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKV--LDDPPQM 658
S Y NSR V R G Y+I+PTTFEP +F L ++++ P + LD+PP
Sbjct: 485 AGSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHT 544
Query: 659 TKAAL 673
++L
Sbjct: 545 CWSSL 549
>U94346-1|AAC51869.1| 639|Homo sapiens calpain-like protease
protein.
Length = 639
Score = 73.3 bits (172), Expect = 8e-13
Identities = 70/245 (28%), Positives = 104/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 2 LIRLRRPLGHGET--PISHIVLXTALWKTIPQYERXRLMIASKG---VWMLFSDFQRLFP 166
+IRLR P G E P S + W+ + + ER ++ + + WM F D R F
Sbjct: 278 MIRLRNPWGEREWNGPWSDT---SEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFT 334
Query: 167 RIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQV 331
I + TS LS + W+ G W R GGC N+ + F NPQ
Sbjct: 335 DIIKCRV-INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQY 389
Query: 332 QIMLNEP-DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKST 484
+ +P D V+I + Q + IGF +YK+ + + + K S
Sbjct: 390 IFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI 449
Query: 485 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKV--LDDPPQM 658
Y NSR V R G Y+I+PTTFEP +F L ++++ P + LD PP
Sbjct: 450 ----YINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDKPPHT 505
Query: 659 TKAAL 673
++L
Sbjct: 506 CWSSL 510
>CR628412-1|CAM28354.1| 437|Homo sapiens calpain 8 protein.
Length = 437
Score = 70.5 bits (165), Expect = 6e-12
Identities = 44/120 (36%), Positives = 59/120 (49%), Gaps = 2/120 (1%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRL--MIASKGVWMLFSDFQRLFPRIE 175
LIRLR P G E + W I + L + WM SDF R F R+E
Sbjct: 281 LIRLRNPWGEVEWSGAWSD-DAPEWNHIDPRRKEELDKKVEDGEFWMSLSDFVRQFSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ +L ++ LS E KW + + G W RG +AGGC+NY + TNPQ +I L+E D
Sbjct: 340 ICNLSPDS----LSSEEVHKWNLVLFNGHWTRGSTAGGCQNYPATYWTNPQFKIRLDEVD 395
>AB117941-1|BAD16650.1| 426|Homo sapiens hUp49 protein.
Length = 426
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 20/164 (12%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLM--IASKG-VWMLFSDFQRLFPRI 172
L+RLR P G E S W + + E+ RL + G WM + DF F ++
Sbjct: 266 LVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKL 324
Query: 173 EMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEP 352
E+ +L + +++ + Q W + +++G W RG SAGGCRN+ + F TNPQ ++ L E
Sbjct: 325 EICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEE 380
Query: 353 D----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 433
D + +++L Q + + + IGF++Y++PK
Sbjct: 381 DDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 424
>BC007553-1|AAH07553.2| 672|Homo sapiens calpain 10 protein.
Length = 672
Score = 60.1 bits (139), Expect = 8e-09
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = +2
Query: 233 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 394
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 395 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 568
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 569 FEPREEAQFTLXI 607
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMKVL 640
+F L ++S + + +
Sbjct: 479 GEFLLRVFSTGRVSLSAI 496
>BC004260-1|AAH04260.1| 672|Homo sapiens calpain 10 protein.
Length = 672
Score = 60.1 bits (139), Expect = 8e-09
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = +2
Query: 233 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 394
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 395 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 568
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 569 FEPREEAQFTLXI 607
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMKVL 640
+F L ++S + + +
Sbjct: 479 GEFLLRVFSTGRVSLSAI 496
>AK074807-1|BAC11220.1| 672|Homo sapiens protein ( Homo sapiens
cDNA FLJ90326 fis, clone NT2RP2001903, weakly similar to
CALPAIN, LARGE [CATALYTIC] SUBUNIT (EC 3.4.22.17). ).
Length = 672
Score = 60.1 bits (139), Expect = 8e-09
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = +2
Query: 233 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 394
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 395 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 568
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 569 FEPREEAQFTLXI 607
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMKVL 640
+F L ++S + + +
Sbjct: 479 GEFLLRVFSTGRVSLSAI 496
>AF089088-1|AAG17966.1| 672|Homo sapiens calpain-like protease
CAPN10a protein.
Length = 672
Score = 60.1 bits (139), Expect = 8e-09
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = +2
Query: 233 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 394
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 395 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 568
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 569 FEPREEAQFTLXI 607
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMKVL 640
+F L ++S + + +
Sbjct: 479 GEFLLRVFSTGRVSLSAI 496
>AC124862-2|AAX88944.1| 672|Homo sapiens unknown protein.
Length = 672
Score = 60.1 bits (139), Expect = 8e-09
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = +2
Query: 233 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 394
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 395 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 568
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 569 FEPREEAQFTLXI 607
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMKVL 640
+F L ++S + + +
Sbjct: 479 GEFLLRVFSTGRVSLSAI 496
>AB058748-1|BAB47474.1| 705|Homo sapiens KIAA1845 protein protein.
Length = 705
Score = 60.1 bits (139), Expect = 8e-09
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Frame = +2
Query: 233 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 394
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 546 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 604
Query: 395 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 568
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 605 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 662
Query: 569 FEPREEAQFTLXI 607
+ P E FT+ I
Sbjct: 663 YLPDTEGAFTVTI 675
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 335 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 394
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 395 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 453
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 454 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 511
Query: 587 AQFTLXIYSNKPLKMKVL 640
+F L ++S + + +
Sbjct: 512 GEFLLRVFSTGRVSLSAI 529
>CR628412-2|CAM28355.1| 381|Homo sapiens calpain 8 protein.
Length = 381
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/102 (35%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRL--MIASKGVWMLFSDFQRLFPRIE 175
LIRLR P G E + W I + L + WM SDF R F R+E
Sbjct: 281 LIRLRNPWGEVEWSGAWSD-DAPEWNHIDPRRKEELDKKVEDGEFWMSLSDFVRQFSRLE 339
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNY 301
+ +L ++ LS E KW + + G W RG +AGGC+NY
Sbjct: 340 ICNLSPDS----LSSEEVHKWNLVLFNGHWTRGSTAGGCQNY 377
>AF089090-1|AAG17968.1| 544|Homo sapiens calpain-like protease
CAPN10b protein.
Length = 544
Score = 55.6 bits (128), Expect = 2e-07
Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 28/219 (12%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMKVLDDPPQMTKAALIKAXPGSDSN 703
+F L ++S + ++ L P + A P + S+
Sbjct: 479 GEFLLRVFSTGRVSLRAL-APAASASLCISTAGPVTPSS 516
>AF089092-1|AAG17970.1| 513|Homo sapiens calpain-like protease
CAPN10d protein.
Length = 513
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/196 (23%), Positives = 81/196 (41%), Gaps = 28/196 (14%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + ++EP V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREE 586
G ++K+ K + + T Y R+V RC+L G YL +P+TF
Sbjct: 421 GLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--DREVHLRCELSPGYYLAVPSTFLKDAP 478
Query: 587 AQFTLXIYSNKPLKMK 634
+F L ++S + ++
Sbjct: 479 GEFLLRVFSTGRVSLR 494
>AK127398-1|BAC86959.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ45489 fis, clone BRTHA2005448, highly similar
to Mus musculus calpain 12 (Capn12). ).
Length = 719
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Frame = +2
Query: 2 LIRLRRPLGHGETPISHIVLXTALWKTIPQYERXRLMIASKG--VWMLFSDFQRLFPRIE 175
L+RLR P G E + W T+P R L++ + WM DF F ++
Sbjct: 278 LLRLRNPWGCVEWTGAWSDSCPR-WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQ 336
Query: 176 MVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 355
+ L E E W + QG W RG ++GG + F TNPQ ++ L EPD
Sbjct: 337 ICSLSPEVLGPS---PEGGGWHVHTFQGRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPD 393
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Frame = +2
Query: 404 IGFSVYKMPKFLT----ETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTF 571
+GF V+++P+ L + R+ S + R V++RC L G YL++P+T
Sbjct: 448 VGFHVFQIPEELLGLWDSPRSHALLPRLLRADRSPLSARRDVTRRCCLRPGHYLVVPSTA 507
Query: 572 EPREEAQFTLXIYSNKPLKMKVLDD 646
+EA FTL ++S + +DD
Sbjct: 508 HAGDEADFTLRVFSERRHTAVEIDD 532
>AF089091-1|AAG17969.1| 517|Homo sapiens calpain-like protease
CAPN10c protein.
Length = 517
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/189 (23%), Positives = 87/189 (46%), Gaps = 30/189 (15%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN F
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGF 361
Query: 311 FHTNPQVQIMLNEPDTVIISLNQ--------------------HSIMEP--------KVI 406
+NP+ + +++P V I++ Q H+ P + +
Sbjct: 362 -PSNPKFWLRVSKPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420
Query: 407 GFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPR 580
G ++K+P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T+ P
Sbjct: 421 GLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPSTYLPD 478
Query: 581 EEAQFTLXI 607
E FT+ I
Sbjct: 479 TEGAFTVTI 487
>BT007322-1|AAP35986.1| 309|Homo sapiens calpain 3, (p94) protein.
Length = 309
Score = 48.0 bits (109), Expect = 4e-05
Identities = 19/41 (46%), Positives = 29/41 (70%)
Frame = +2
Query: 497 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 25 YINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 65
>BC003169-1|AAH03169.1| 309|Homo sapiens calpain 3, (p94) protein.
Length = 309
Score = 48.0 bits (109), Expect = 4e-05
Identities = 19/41 (46%), Positives = 29/41 (70%)
Frame = +2
Query: 497 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNK 619
Y N R+VSQR +L Y+I+P+T+EP +E +F L ++S K
Sbjct: 25 YINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 65
>AF089093-1|AAG17971.1| 444|Homo sapiens calpain-like protease
CAPN10e protein.
Length = 444
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Frame = +2
Query: 131 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 310
W+ +F R F + + + TE + +E+ + G W +G SAGGCRN +
Sbjct: 302 WVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNN-SG 360
Query: 311 FHTNPQVQIMLNEPDTVIISLNQHS 385
F +NP+ + +++P V I++ Q S
Sbjct: 361 FPSNPKFWLRVSKPSEVYIAVLQRS 385
>AK124751-1|BAC85936.1| 210|Homo sapiens protein ( Homo sapiens
cDNA FLJ42761 fis, clone BRAWH3002574, highly similar
to Calpain 2, large [catalytic] subunit precursor (EC
3.4.22.17). ).
Length = 210
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/50 (34%), Positives = 31/50 (62%)
Frame = +2
Query: 497 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXIYSNKPLKMKVLDD 646
+ N R+V R +L G Y+++P+TFEP ++ F + ++S K + +DD
Sbjct: 48 FINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDD 97
>BC056202-1|AAH56202.1| 813|Homo sapiens calpain 7 protein.
Length = 813
Score = 39.5 bits (88), Expect = 0.013
Identities = 35/132 (26%), Positives = 55/132 (41%)
Frame = +2
Query: 245 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYK 424
K G W G SAGGC N+ NP Q + + ++I L +GF V
Sbjct: 690 KRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYS---VGFEVVT 745
Query: 425 MPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLX 604
+ L + F ++ + Y + + SG + I+P+TF P++E F L
Sbjct: 746 VST-LGDPGPHGFLRKS----SGDYRCGFCYLELENIPSGIFNIIPSTFLPKQEGPFFLD 800
Query: 605 IYSNKPLKMKVL 640
S P+K+ L
Sbjct: 801 FNSIIPIKITQL 812
>AB028639-1|BAA78730.1| 813|Homo sapiens PalBH protein.
Length = 813
Score = 39.5 bits (88), Expect = 0.013
Identities = 35/132 (26%), Positives = 55/132 (41%)
Frame = +2
Query: 245 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYK 424
K G W G SAGGC N+ NP Q + + ++I L +GF V
Sbjct: 690 KRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYS---VGFEVVT 745
Query: 425 MPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLX 604
+ L + F ++ + Y + + SG + I+P+TF P++E F L
Sbjct: 746 VST-LGDPGPHGFLRKS----SGDYRCGFCYLELENIPSGIFNIIPSTFLPKQEGPFFLD 800
Query: 605 IYSNKPLKMKVL 640
S P+K+ L
Sbjct: 801 FNSIIPIKITQL 812
>AF089096-1|AAG17974.1| 138|Homo sapiens calpain-like protease
CAPN10h protein.
Length = 138
Score = 33.5 bits (73), Expect = 0.83
Identities = 13/34 (38%), Positives = 23/34 (67%)
Frame = +2
Query: 506 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLXI 607
+++VS+ C L +G Y ++P+T+ P E FT+ I
Sbjct: 75 AQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 108
>L37378-1|AAA74451.1| 1108|Homo sapiens guanylyl cyclase protein.
Length = 1108
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +1
Query: 148 LPAPLPPDRDGALGHGDQP--SGAFAVRETE 234
LP P P D+DG +GHG QP AF R+ E
Sbjct: 1070 LPVPPPVDKDGQVGHGLQPVEIAAFQRRKAE 1100
>AL031387-4|CAB41303.1| 1108|Homo sapiens guanylate cyclase 2F,
retinal protein.
Length = 1108
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +1
Query: 148 LPAPLPPDRDGALGHGDQP--SGAFAVRETE 234
LP P P D+DG +GHG QP AF R+ E
Sbjct: 1070 LPVPPPVDKDGQVGHGLQPVEIAAFQRRKAE 1100
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,535,828
Number of Sequences: 237096
Number of extensions: 2169323
Number of successful extensions: 5434
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 5098
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5352
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -