Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-1947
(750 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 232 9e-61
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 232 9e-61
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 232 9e-61
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 232 9e-61
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 232 9e-61
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 232 9e-61
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 232 9e-61
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 232 1e-60
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 231 2e-60
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 229 1e-59
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 225 1e-58
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 222 9e-58
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 222 9e-58
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 222 9e-58
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 222 9e-58
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 222 9e-58
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 222 9e-58
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 222 9e-58
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 222 9e-58
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 42 0.003
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 232 bits (568), Expect = 9e-61
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 232 bits (567), Expect = 1e-60
Identities = 112/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKRKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 231 bits (566), Expect = 2e-60
Identities = 111/198 (56%), Positives = 148/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AE+ELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPYLYRPVAVALDTKGPEIRTGLIKGSGTAELELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN LGS
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 229 bits (559), Expect = 1e-59
Identities = 111/198 (56%), Positives = 147/198 (74%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 331 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLTTSS 510
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELK G T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 511 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXMLGSX 690
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +EN L S
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLVSK 206
Query: 691 KGVNLXXIPVDLPAXSEK 744
KGVNL VDLPA SEK
Sbjct: 207 KGVNLPGAAVDLPAVSEK 224
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 225 bits (551), Expect = 1e-58
Identities = 112/201 (55%), Positives = 146/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 39 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 98
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
TI N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 99 TIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 155
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q +S + L +EN +L
Sbjct: 156 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKISPEGLVTQVENGGVL 215
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 216 GSRKGVNLPGAQVDLPGLSEQ 236
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 62 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 121
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 122 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 178
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 179 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 238
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 239 GSRKGVNLPGAQVDLPGLSEQ 259
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 83 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 142
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 143 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 199
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 200 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 259
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 260 GSRKGVNLPGAQVDLPGLSEQ 280
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 95 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 154
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 155 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 211
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 212 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 271
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 272 GSRKGVNLPGAQVDLPGLSEQ 292
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQ 267
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQ 267
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 81 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 140
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 141 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 197
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 198 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 257
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 258 GSRKGVNLPGAQVDLPGLSEQ 278
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 61 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 120
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 121 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 177
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 178 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 237
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 238 GSRKGVNLPGAQVDLPGLSEQ 258
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 222 bits (543), Expect = 9e-58
Identities = 110/201 (54%), Positives = 145/201 (72%), Gaps = 3/201 (1%)
Frame = +1
Query: 151 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 330
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 331 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKXGETIKLT 501
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL G + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 502 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENXXML 681
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +EN +L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 682 GSXKGVNLXXIPVDLPAXSEK 744
GS KGVNL VDLP SE+
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQ 267
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 41.5 bits (93), Expect = 0.003
Identities = 21/35 (60%), Positives = 22/35 (62%)
Frame = +1
Query: 640 ADTLTCTIENXXMLGSXKGVNLXXIPVDLPAXSEK 744
AD L +EN LGS KGVNL VDLPA SEK
Sbjct: 2 ADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEK 36
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,105,520
Number of Sequences: 237096
Number of extensions: 2098080
Number of successful extensions: 5329
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5176
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5319
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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